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src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2017\/08\/2-54.jpg\" alt=\"\" width=\"500\" height=\"397\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2017\/08\/2-54.jpg 500w, \/\/m.iemloyee.com\/wp-content\/uploads\/2017\/08\/2-54-300x238.jpg 300w\" sizes=\"(max-width: 500px) 100vw, 500px\" 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\u91d1\u7eb3\u7c73\u7c92\u5b50\uff0850 mg \u4e8ePBS\u4e2d\uff09\u6216\u76d0\u6c34\u8fdb\u5165C57B1\/6\u5c0f\u9f20\u4f53\u5185\uff08\u6bcf\u7ec44\u4e2a\u6837\u54c1\uff0c\u4ece\u4e24\u4e2a\u5355\u72ec\u7684\u5b9e\u9a8c\u6c47\u96c6\uff09\u3002\u7ed9\u836f\u4e24\u5c0f\u65f6\u540e\uff0c\u53d6\u80ba\u7ec4\u7ec7\u5e76\u7528\u6807\u8bb0\u6297\u4f53\u67d3\u8272\uff0c\u7136\u540e\u901a\u8fc7\u8d28\u8c31\u6d41\u5f0f\u7ec6\u80de\u6280\u672f\u6216\u6d41\u5f0f\u7ec6\u80de\u6280\u672f\u8fdb\u884c\u5206\u6790\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-97521\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2017\/08\/3-47.jpg\" alt=\"\" width=\"500\" height=\"784\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2017\/08\/3-47.jpg 500w, \/\/m.iemloyee.com\/wp-content\/uploads\/2017\/08\/3-47-191x300.jpg 191w\" sizes=\"(max-width: 500px) 100vw, 500px\" \/><\/p>\n<p>\uff08a\uff09\u5c06\u4e0e\u91d1\u5c5e\uff08<sup>165<\/sup>Ho\uff09\u87af\u5408\u7684\u6216\u7528FITC\u6807\u8bb0\u7684CD326\u6297\u4f53\u4e0e\u80ba\u7ec6\u80de\u4e00\u8d77\u8fdb\u884c\u67d3\u8272\uff0c\u540c\u65f6\u7528\u8d28\u8c31\u6d41\u5f0f\u7ec6\u80de\u6280\u672f\u548c\u6d41\u5f0f\u7ec6\u80de\u6280\u672f\u8fdb\u884c\u5206\u6790\uff1b<\/p>\n<p>\uff08b\uff09\u901a\u8fc7\u8d28\u8c31\u6d41\u5f0f\u7ec6\u80de\u6280\u672f\u68c0\u6d4b\u4e3aAuNP\u9633\u6027\u7684\u4e0a\u76ae\u7ec6\u80de\u4e0e\u975e\u4e0a\u76ae\u7ec6\u80de\u7684\u5e73\u5747\u767e\u5206\u6570\uff1b<\/p>\n<p>\uff08c\uff09\u91c7\u7528\u8d28\u8c31\u6d41\u5f0f\u7ec6\u80de\u6280\u672f\u65b9\u6cd5\u5bf9500\u4e07\u4e2a\u88ab\u5b9a\u4e49\u4e3aCD326<sup>&#8211;<\/sup>BODIPY<sup>&#8211;<\/sup>\u7684\u7ec6\u80de\u8fdb\u884c\u5206\u9009\uff0c\u5e76\u7528\u7535\u611f\u8026\u5408\u7b49\u79bb\u5b50\u4f53\u539f\u5b50\u53d1\u5c04\u5149\u8c31\u5bf9\u6bcf\u4e2a\u7ec6\u80de\u4e2d\u7684\u91d1\u7eb3\u7c73\u7c92\u5b50\u8fdb\u884c\u5b9a\u91cf\uff1b<\/p>\n<p>\uff08d\uff09\u901a\u8fc7\u8d28\u8c31\u6d41\u5f0f\u7ec6\u80de\u6280\u672f\u65b9\u6cd5\u76f4\u63a5\u6d4b\u5b9a\u5355\u4e2a\u7ec6\u80de\u4e2d\u7684\u91d1\u7eb3\u7c73\u7c92\u5b50\u6570\uff1b<\/p>\n<p>\uff08e-k\uff09\u901a\u8fc7\u80ba\u6c14\u7ba1\u5f80\u80ba\u4e2d\u6ce8\u51651 \u03bcg MUS\/OT \u91d1\u7eb3\u7c73\u7c92\u5b5024\u5c0f\u65f6\u540e,\u5c06\u7ec6\u80de\u5206\u79bb\u51fa\u6765\uff0c\u901a\u8fc7\u5178\u578b\u7684\u8d28\u8c31\u6d41\u5f0f\u7ec6\u80de\u6280\u672f\u65b9\u6cd5\u8fdb\u884c\u5206\u6790\uff1b<\/p>\n<p>\uff08l\uff09B\u7ec6\u80de\uff08CD45<sup>+<\/sup> B220<sup>+<\/sup> CD3<sup>&#8211;<\/sup>\uff09\u3001T\u7ec6\u80de\uff08CD45<sup>+<\/sup> B220<sup>&#8211;<\/sup> CD3<sup>+<\/sup>\uff09\u3001\u6811\u7a81\u72b6\u7ec6\u80de\uff08DCs\uff0cCD45<sup>+<\/sup> CD11c<sup>hi<\/sup>CD11b<sup>+<\/sup> CD64<sup>&#8211;<\/sup>\uff09\u548c\u80ba\u6ce1\u5de8\u566c\u7ec6\u80de\uff08AMs\uff0cCD45<sup>+<\/sup> CD11c<sup>hi<\/sup> CD11b<sup>+<\/sup> CD64<sup>+<\/sup>\uff09\u4e2d\u9ec4\u91d1\u5f3a\u5ea6\u76f4\u65b9\u56fe\u3002<\/p>\n<p><strong>\u56fe4\uff1a\u6811\u7a81\u72b6\u7ec6\u80de\u6444\u53d6\u4ee5\u53ca\u4e0e\u6709\u6548\u75ab\u82d7\u5e94\u7b54\u76f8\u5173\u7684MUS\/OT\u91d1\u7eb3\u7c73\u7c92\u5b50\u3002<\/strong><\/p>\n<p><strong><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-97522\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2017\/08\/4-39.jpg\" alt=\"\" width=\"500\" height=\"686\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2017\/08\/4-39.jpg 500w, \/\/m.iemloyee.com\/wp-content\/uploads\/2017\/08\/4-39-219x300.jpg 219w\" sizes=\"(max-width: 500px) 100vw, 500px\" \/><\/strong><\/p>\n<p>\uff08a\uff09\u5c06300 mg MUS\/OT\u6216PEG\u91d1\u7eb3\u7c73\u9897\u7c92\u5206\u522b\u6ce8\u5c04\u5230C57B1\/6\u5c0f\u9f20\uff08\u6bcf\u7ec45\u53ea\u5c0f\u9f20\uff09\u4f53\u5185\uff0c24\u5c0f\u65f6\u540e\u901a\u8fc7\u7535\u611f\u8026\u5408\u7b49\u79bb\u5b50\u4f53\u539f\u5b50\u53d1\u5c04\u5149\u8c31\u5bf9\u5728\u8170\u3001\u8179\u80a1\u6c9f\u3001\u814b\u7a9d\u4e2d\u6dcb\u5df4\u7ed3\u7684\u603b\u91d1\u7eb3\u7c73\u9897\u7c92\u6570\u8fdb\u884c\u5b9a\u91cf\u5206\u6790\uff1b<\/p>\n<p>\uff08b\uff0cc\uff09\u5c06300 mg MUS\/OT\u3001MPSA\u6216PEG\u91d1\u7eb3\u7c73\u9897\u7c92\u5206\u522b\u6ce8\u5c04\u5230C57B1\/6\u5c0f\u9f20\uff08\u6bcf\u7ec4\u5c0f\u9f20\u6570n\u22653\uff09\u4f53\u5185\uff0c24\u5c0f\u65f6\u540e\u5207\u9664\u6dcb\u5df4\u7ed3\u5e76\u5bf9\u5176\u8fdb\u884c\u67d3\u8272\u548c\u5206\u6790\u3002\u7528Au\u7684\u76f4\u65b9\u56fe\u663e\u793a\u4e0d\u540c\u767d\u7ec6\u80de\u7fa4\u4f53\u4e2d\u91d1\u7eb3\u7c73\u9897\u7c92\u7684\u6c34\u5e73\uff08b\uff09\u4ee5\u53ca\u6dcb\u5df4\u7ed3\u7ec6\u80de\u7fa4\u4f53\u5e73\u5747\u6bcf\u4e2a\u7ec6\u80de\u4e2d\u7684\u7eb3\u7c73\u9897\u7c92\u6570\u91cf\uff08c\uff09\uff1b<\/p>\n<p>\uff08d\uff09SIINFEKL\u80bd\u7ed3\u6784\u53ca\u5176\u4e0eMUS\/OT\u7eb3\u7c73\u9897\u7c92\u8868\u9762\u8026\u5408\u7684\u793a\u610f\u56fe\uff1b<\/p>\n<p>\uff08e-i\uff09\u5c068 mg CpG\u548c\u4e0eMUS\/OT\uff0810 mg \u80bd\uff09\u300150 mg SIINFEKL \u80bd\u300110 mg SIINFEKL \u80bd\u621610 mg SIINFEKL 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href=\"https:\/\/www.nature.com\/articles\/ncomms14069\" target=\"_blank\" rel=\"noopener\">High-throughput quantitation of inorganic nanoparticle biodistribution at the single-cell level using mass cytometry<\/a>\uff08Nat.Commun., \u00a02017, DOI: 10.1038\/ncomms14069\uff09<\/p>\n<p>\u672c\u6587\u7531\u6750\u6599\u4eba\u7f16\u8f91\u90e8\u65b0\u4eba\u7ec4\u96ea\u7430\u4f9b\u7a3f\uff0c\u6750\u6599\u725b\u7f16\u8f91\u6574\u7406\u3002<\/p>\n<p>\u6750\u6599\u725b\u7f51\u4e13\u6ce8\u4e8e\u8ddf\u8e2a\u6750\u6599\u9886\u57df\u79d1\u6280\u53ca\u884c\u4e1a\u8fdb\u5c55\uff0c\u8fd9\u91cc\u6c47\u96c6\u4e86\u5404\u5927\u9ad8\u6821\u7855\u535a\u751f\u3001\u4e00\u7ebf\u79d1\u7814\u4eba\u5458\u4ee5\u53ca\u884c\u4e1a\u4ece\u4e1a\u8005\uff0c\u5982\u679c\u60a8\u5bf9\u4e8e\u8ddf\u8e2a\u6750\u6599\u9886\u57df\u79d1\u6280\u8fdb\u5c55\uff0c\u89e3\u8bfb\u9ad8\u6c34\u5e73\u6587\u7ae0\u6216\u662f\u8bc4\u8ff0\u884c\u4e1a\u6709\u5174\u8da3\uff0c<a href=\"\/\/m.iemloyee.com\/25127.html\" target=\"_blank\" rel=\"noopener\">\u70b9\u6211\u52a0\u5165\u7f16\u8f91\u90e8<\/a>\u3002<\/p>\n<p>\u6750\u6599\u6d4b\u8bd5\uff0c\u6570\u636e\u5206\u6790\uff0c<a href=\"http:\/\/www.ceshigu.com\/\" target=\"_blank\" rel=\"noopener\">\u4e0a\u6d4b\u8bd5\u8c37<\/a>\uff01<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u3010\u5f15\u8a00\u3011 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