{"id":86743,"date":"2017-06-17T06:30:40","date_gmt":"2017-06-16T22:30:40","guid":{"rendered":"\/\/m.iemloyee.com\/?p=86743"},"modified":"2017-06-16T16:13:06","modified_gmt":"2017-06-16T08:13:06","slug":"%e7%a7%91%e6%8a%80%e8%b5%84%e8%ae%af%e5%86%99%e4%bd%9c%e5%a4%a7%e8%b5%9b%ef%bd%9c%e5%90%b4%e5%af%8c%e6%a0%b9%e9%99%88%e6%88%98sci-china-mater-%e6%9c%80%e6%96%b0%e7%bb%bc%e8%bf%b0%ef%bc%9a%e5%9f%ba","status":"publish","type":"post","link":"\/\/m.iemloyee.com\/?p=86743","title":{"rendered":"\u79d1\u6280\u8d44\u8baf\u5199\u4f5c\u5927\u8d5b\uff5c\u5434\u5bcc\u6839&#038;\u9648\u6218Sci.China Mater.\u6700\u65b0\u7efc\u8ff0\uff1a\u57fa\u4e8e\u6c34\u51dd\u80f6\u7684\u5149\u7597\uff0c\u5bf9\u6297\u764c\u75c7\u548c\u7ec6\u83cc\u611f\u67d3"},"content":{"rendered":"<p><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-81477 aligncenter\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2017\/05\/\u8d44\u8baf\u5927\u8d5b-\u526f\u672c-2-1.png\" alt=\"\" width=\"740\" height=\"416\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2017\/05\/\u8d44\u8baf\u5927\u8d5b-\u526f\u672c-2-1.png 740w, \/\/m.iemloyee.com\/wp-content\/uploads\/2017\/05\/\u8d44\u8baf\u5927\u8d5b-\u526f\u672c-2-1-300x169.png 300w\" sizes=\"(max-width: 740px) 100vw, 740px\" \/><\/p>\n<p>\u6750\u6599\u4eba\u9996\u5c4a\u79d1\u6280\u8d44\u8baf\u5199\u4f5c\u5927\u8d5b\u81ea5\u670813\u65e5\u53d1\u5e03\u5f81\u7a3f\u901a\u77e5\u4ee5\u6765\uff08<a href=\"\/\/m.iemloyee.com\/80668.html\" target=\"_blank\" rel=\"noopener noreferrer\">\u53c2\u8d5b\u8be6\u60c5\u8bf7\u6233\u6211<\/a>\uff09\uff0c\u53d7\u5230\u8bfb\u8005\u4eec\u7684\u5e7f\u6cdb\u5173\u6ce8\u3002\u53d7\u5230\u8bfb\u8005\u4eec\u7684\u5e7f\u6cdb\u5173\u6ce8\u3002\u611f\u8c22\u652f\u6301\u5355\u4f4dTaylor\u00a0&amp;\u00a0Francis\u00a0Group\uff0c\u79d1\u5b66\u51fa\u7248\u793e\uff0cMDPI\uff0cNational Science Review\uff0cChinese Science Bulletin\uff0cScience China Materials\uff0cScience China Chemistry \uff0cNano-Micro Letters\u5bf9\u672c\u6b21\u5927\u8d5b\u7684\u652f\u6301\uff01\u4e3a\u4e86\u7ed9\u66f4\u591a\u6750\u6599\u4eba\u63d0\u4f9b\u5145\u5206\u5c55\u793a\u7684\u7a97\u53e3\uff0c\u5927\u8d5b\u6295\u7a3f\u65f6\u95f4\u5c06\u5ef6\u671f\u81f37\u670820\u65e5\u3002\u672c\u6587\u7531<strong>\u4e1c\u5357\u5927\u5b66\u5f20\u6653\u4e1c<\/strong>\u6295\u7a3f\u3002<\/p>\n<p><strong>\u5f15\u8a00<\/strong><\/p>\n<p>\u5149\u7597\u662f\u5229\u7528\u5149\u7684\u8f90\u7167\u6765\u6cbb\u7597\u75be\u75c5\u7684\u65b9\u6cd5\uff0c\u4e3b\u8981\u5305\u62ec\u5149\u52a8\u529b\u7597\u6cd5\u548c\u5149\u70ed\u7597\u6cd5\u7b49\u3002\u8fd1\u4e9b\u5e74\u6765\uff0c\u5149\u7597\u53ca\u5176\u8054\u5408\u7597\u6cd5\u88ab\u9010\u6e10\u5e94\u7528\u4e8e\u6297\u764c\u548c\u6297\u83cc\u9886\u57df\u4e2d\u3002\u53e6\u4e00\u65b9\u9762\uff0c\u6c34\u51dd\u80f6\u56e0\u4e3a\u80fd\u591f\u5728\u5176\u5185\u90e8\u7684\u4e09\u7ef4\u7f51\u7edc\u4e2d\u4fdd\u6709\u5927\u91cf\u7684\u6c34\uff0c\u5e76\u5728\u7ec4\u6210\u6c34\u51dd\u80f6\u7684\u9ad8\u5206\u5b50\u548c\u6c34\u4ecb\u8d28\u4e2d\u8d1f\u8f7d\u5404\u79cd\u4e0d\u540c\u7684\u529f\u80fd\u6027\u5206\u5b50\uff0c\u6240\u4ee5\u5728\u751f\u7269\u533b\u5b66\u9886\u57df\u4e2d\u6709\u7740\u5e7f\u6cdb\u7684\u5e94\u7528\uff0c\u5982\u7528\u4e8e\u836f\u7269\u6216\u7ec6\u80de\u7684\u8f7d\u4f53\u3001\u7ec4\u7ec7\u5de5\u7a0b\u548c\u751f\u7269\u4f20\u611f\u5668\u7b49\u3002\u7279\u522b\u5730\uff0c\u5c06\u6c34\u51dd\u80f6\u4f5c\u4e3a\u836f\u7269\u8f93\u8fd0\u7cfb\u7edf\u5728\u5149\u7597\u4e2d\u62e5\u6709\u72ec\u7279\u7684\u4f18\u52bf\u3002<\/p>\n<p>\u6700\u8fd1\uff0c<strong>\u4e1c\u5357\u5927\u5b66\u7684\u5434\u5bcc\u6839\u6559\u6388\u548c\u7f8e\u56fd\u5bc6\u6b47\u6839\u5927\u5b66\u7684\u9648\u6218\u6559\u6388\uff08\u5171\u540c\u901a\u8baf\uff09<\/strong>\u7b49\u4eba\u7efc\u8ff0\u4e86\u6c34\u51dd\u80f6\u5728\u5149\u7597\u4e2d\u7684\u7814\u7a76\u8fdb\u5c55\uff0c\u5e76\u4ee5<strong>\u201cHydrogel-based phototherapy for fighting cancer and bacterial infection\u201d<\/strong>\u4e3a\u9898\u53d1\u8868\u5728<strong>Science China Materials<\/strong>\u671f\u520a\u4e0a\u3002\u8be5\u6587\u91cd\u70b9\u4ecb\u7ecd\u4e86\u4e09\u79cd\u57fa\u4e8e\u6c34\u51dd\u80f6\u7684\u5149\u7597\u65b9\u5f0f\uff1a\u5149\u52a8\u529b\u6cbb\u7597\uff08PDT\uff09\u3001\u5149\u70ed\u6cbb\u7597\uff08PDT\uff09\u548c\u542b\u6709\u5149\u7597\u7684\u8054\u5408\u7597\u6cd5\uff08PCCT\uff09\uff0c\u5e76\u603b\u7ed3\u4e86\u6c34\u51dd\u80f6\u4f5c\u4e3a\u836f\u7269\u8f7d\u4f53\u5728\u8fd9\u4e09\u79cd\u5149\u7597\u65b9\u5f0f\u4e2d\u7684\u4f18\u52bf\uff0c\u6700\u540e\u8ba8\u8bba\u4e86\u6c34\u51dd\u80f6\u5728\u5149\u7597\u5e94\u7528\u4e2d\u7684\u6311\u6218\uff0c\u5e76\u5c55\u671b\u4e86\u672a\u6765\u7684\u53d1\u5c55\u8d8b\u52bf\u3002\u5168\u6587\u7684\u7ed3\u6784\u6846\u67b6\u89c1\u56fe1\u3002<\/p>\n<p style=\"text-align: center;\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-86746 aligncenter\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2017\/06\/1-47.jpg\" alt=\"\" width=\"600\" height=\"369\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2017\/06\/1-47.jpg 600w, \/\/m.iemloyee.com\/wp-content\/uploads\/2017\/06\/1-47-300x185.jpg 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/p>\n<p style=\"text-align: center;\"><strong>\u56fe1 \u7efc\u8ff0\u603b\u89c8\u56fe<\/strong><\/p>\n<p><strong>1.\u00a0<\/strong><strong>\u7b80\u4ecb<\/strong><\/p>\n<p>\u5149\u7597\u4f5c\u4e3a\u4e00\u79cd\u65b0\u5174\u7684\u75be\u75c5\u6cbb\u7597\u65b9\u6cd5\uff0c\u5728\u764c\u75c7\u6cbb\u7597\u548c\u5bf9\u6297\u7ec6\u83cc\u611f\u67d3\u7b49\u65b9\u9762\u6709\u7740\u5e7f\u9614\u5e94\u7528\u524d\u666f\u3002\u5149\u7597\u901a\u5e38\u662f\u5229\u7528\u67d0\u4e9b\u836f\u7269\u5728\u7279\u5b9a\u5149\u7167\u5c04\u4e0b\u53d1\u751f\u53d8\u5316\uff0c\u5982\u5149\u654f\u5242\u53ef\u5728\u5149\u7167\u5c04\u4e0b\u53d1\u751f\u5149\u5316\u5b66\u53cd\u5e94\u5e76\u4ea7\u751f\u6d3b\u6027\u6c27\uff0c\u5bfc\u81f4\u764c\u7ec6\u80de\u548c\u7ec6\u83cc\u7684\u6b7b\u4ea1\uff1b\u8fd8\u6709\u4e00\u4e9b\u8bd5\u5242\u5728\u5149\u7167\u4e0b\u53ef\u4ee5\u4ea7\u751f\u70ed\u91cf\uff0c\u901a\u8fc7\u9ad8\u70ed\uff08hyperthermia\uff09\u6548\u5e94\u5b9e\u73b0\u6740\u6b7b\u7ec6\u80de\u7684\u76ee\u7684\u3002<\/p>\n<p>\u53e6\u4e00\u65b9\u9762\uff0c\u6c34\u51dd\u80f6\u662f\u7531\u9ad8\u5206\u5b50\u805a\u5408\u3001\u5185\u90e8\u542b\u6709\u5927\u91cf\u6c34\u7684\u4e09\u7ef4\u7f51\u7edc\u3002\u56e0\u4e3a\u5176\u7279\u6b8a\u7684\u6027\u8d28\uff0c\u6c34\u51dd\u80f6\u4f5c\u4e3a\u836f\u7269\u8f7d\u4f53\u6709\u7740\u72ec\u7279\u7684\u4f18\u52bf\u3002\u5bf9\u4e8e\u5b8f\u89c2\u51dd\u80f6\uff08macrogel\uff09\u6765\u8bf4\uff0c\u7531\u4e8e\u5176\u8f83\u4f4e\u7684\u6d41\u52a8\u6027\uff0c\u53ef\u4ee5\u957f\u65f6\u95f4\u505c\u7559\u5728\u7279\u5b9a\u90e8\u4f4d\uff0c\u5e76\u4e14\u5b9e\u73b0\u836f\u7269\u7f13\u91ca\u7684\u6548\u679c\uff1b\u800c\u7eb3\u7c73\u51dd\u80f6\uff08nanogel\uff09\u80fd\u591f\u6574\u5408\u7eb3\u7c73\u9897\u7c92\u548c\u6c34\u51dd\u80f6\u4e24\u8005\u72ec\u7279\u7684\u6027\u8d28\u3002\u5c06\u6c34\u51dd\u80f6\u4f5c\u4e3a\u5149\u7597\u836f\u7269\u7684\u8f7d\u4f53\uff0c\u53ef\u4ee5\u5b9e\u73b0\u66f4\u597d\u7684\u6cbb\u7597\u6548\u679c\u3002<\/p>\n<p><strong>2. \u57fa\u4e8e\u6c34\u51dd\u80f6\u7684\u5149\u52a8\u529b\u7597\u6cd5<\/strong><\/p>\n<p>\u5149\u52a8\u529b\u6cbb\u7597\u901a\u5e38\u5229\u7528\u901a\u8fc7\u5149\u654f\u5242\u5728\u5149\u7167\u4e0b\u4f1a\u53d1\u751f\u4e00\u7cfb\u5217\u5149\u5316\u5b66\u53cd\u5e94\uff0c\u4ea7\u751f\u5355\u7ebf\u6001\u6c27\u548c\u5176\u4ed6\u6d3b\u6027\u6c27\uff0c\u6c27\u5316\u7ec4\u7ec7\u548c\u7ec6\u80de\u4e2d\u7684\u5404\u79cd\u751f\u7269\u5927\u5206\u5b50\uff0c\u6700\u7ec8\u4f7f\u7ec6\u80de\u6b7b\u4ea1\uff0c\u8fbe\u5230\u6cbb\u7597\u76ee\u7684\u3002\u7531\u4e8e\u5355\u7ebf\u6001\u6c27\u548c\u5176\u4ed6\u6c27\u81ea\u7531\u57fa\u901a\u5e38\u4e0d\u5177\u6709\u9009\u62e9\u6027\u4e14\u5bff\u547d\u8f83\u77ed\uff0c\u6240\u4ee5\u5c06\u5149\u654f\u5242\u7cbe\u786e\u8f93\u9001\u5230\u75c5\u7076\u533a\u5341\u5206\u91cd\u8981\uff0c\u800c\u6c34\u51dd\u80f6\u6070\u597d\u53ef\u4ee5\u5b9e\u73b0\u8fd9\u4e00\u70b9\u3002<\/p>\n<p><strong>2.1 \u57fa\u4e8e\u7eb3\u7c73\u51dd\u80f6\u7684\u5149\u52a8\u529b\u6297\u764c\u7597\u6cd5<\/strong><\/p>\n<p>\u7eb3\u7c73\u51dd\u80f6\u540c\u65f6\u62e5\u6709\u6c34\u51dd\u80f6\u548c\u7eb3\u7c73\u9897\u7c92\u7684\u6027\u8d28\uff0c\u5728\u5149\u52a8\u529b\u6cbb\u7597\u4e2d\u901a\u5e38\u5177\u6709\u4ee5\u4e0b\u51e0\u4e2a\u4f18\u52bf\uff1a\uff081\uff09\u53ef\u6709\u6548\u5730\u8fbe\u5230\u80bf\u7624\u533a\uff1a\u7eb3\u7c73\u51dd\u80f6\u7684\u7c92\u5f84\u8f83\u4e3a\u5408\u9002\uff0c\u53ef\u4ee5\u5229\u7528\u5b9e\u4f53\u7624\u7684\u9ad8\u901a\u900f\u6027\u548c\u6ede\u7559\uff08EPR\uff09\u6548\u5e94\uff0c\u5c06\u836f\u7269\u5206\u5b50\u9012\u9001\u5230\u80bf\u7624\u533a\uff1b\uff082\uff09\u53ef\u964d\u4f4e\u5149\u654f\u5242\u7684\u5168\u8eab\u6bd2\u6027\uff1a\u5c06\u5149\u654f\u5242\u5206\u5b50\u5305\u88f9\u5728\u7eb3\u7c73\u51dd\u80f6\u5185\u90e8\u53ef\u4ee5\u6709\u6548\u9632\u6b62\u5149\u654f\u5242\u7684\u5916\u6cc4\uff0c\u51cf\u5c11\u5149\u654f\u5242\u5728\u6b63\u5e38\u7ec4\u7ec7\u7684\u5bcc\u96c6\uff1b\uff083\uff09\u53ef\u4fee\u9970\u6027\uff1a\u5728\u7eb3\u7c73\u51dd\u80f6\u7684\u5916\u90e8\u53ef\u4ee5\u4fee\u9970\u9776\u5411\u5206\u5b50\u3001\u6210\u50cf\u8bd5\u5242\u7b49\uff0c\u80fd\u591f\u5b9e\u73b0\u66f4\u597d\u7684\u6cbb\u7597\u6548\u679c\uff0c\u540c\u65f6\u53ef\u4ee5\u8ffd\u8e2a\u836f\u7269\u5206\u5b50\u7684\u5206\u5e03\u548c\u4ee3\u8c22\u60c5\u51b5\u3002\u6bd4\u5982\uff0c\u7814\u7a76\u4eba\u5458\u5728\u805a\u4e19\u70ef\u9170\u80fa\u7eb3\u7c73\u51dd\u80f6\u5f62\u6210\u8fc7\u7a0b\u4e2d\u63ba\u5165\u5149\u654f\u5242\u548c\u8367\u5149\u63a2\u9488\uff0c\u5e76\u4e14\u5728\u7eb3\u7c73\u51dd\u80f6\u8868\u9762\u4fee\u9970\u4e0a\u9776\u5411\u57fa\u56e2\uff0c\u5b9e\u73b0\u8bca\u7597\u4e00\u4f53\u5316\uff08\u56fe2\uff09\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-86747 aligncenter\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2017\/06\/2-43.jpg\" alt=\"\" width=\"600\" height=\"690\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2017\/06\/2-43.jpg 600w, \/\/m.iemloyee.com\/wp-content\/uploads\/2017\/06\/2-43-261x300.jpg 261w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/p>\n<p style=\"text-align: center;\"><strong>\u56fe2 \u805a\u4e19\u70ef\u9170\u80fa\u7eb3\u7c73\u51dd\u80f6\u4f5c\u4e3a\u5149\u654f\u5242\u8f7d\u4f53\u7684\u5236\u5907\u793a\u610f\u56fe\uff08\u56fe\u7247\u6765\u6e90\uff1aWang et al., ACS Nano 2012, 6, 6843\uff09<\/strong><\/p>\n<p><strong>2.2 \u57fa\u4e8e\u5b8f\u89c2\u51dd\u80f6\u7684\u5149\u52a8\u529b\u7597\u6cd5<\/strong><\/p>\n<p>\u4e0e\u7eb3\u7c73\u51dd\u80f6\u4e00\u6837\uff0c\u5b8f\u89c2\u51dd\u80f6\u53ef\u4ee5\u5728\u5185\u90e8\u5305\u88f9\u5177\u6709\u5149\u54cd\u5e94\u80fd\u529b\u7684\u5206\u5b50\uff0c\u751a\u81f3\u662f\u7eb3\u7c73\u9897\u7c92\u3002\u4f46\u662f\uff0c\u5b8f\u89c2\u51dd\u80f6\u4e00\u822c\u6ca1\u6709\u9776\u5411\u80fd\u529b\uff0c\u9700\u8981\u9884\u5148\u5224\u65ad\u51fa\u80bf\u7624\u7684\u4f4d\u7f6e\u3002\u7136\u540e\u5229\u7528\u5b8f\u89c2\u51dd\u80f6\u7684\u4f4e\u6d41\u52a8\u6027\u6216\u8005\u5149\u805a\u5408\u53cd\u5e94\u5f62\u6210\u6c34\u51dd\u80f6\uff0c\u5c06\u5149\u654f\u5242\u957f\u65f6\u95f4\u6ede\u7559\u5728\u80bf\u7624\u533a\u57df\uff0c\u6765\u51cf\u5c11\u5149\u654f\u5242\u5bf9\u6b63\u5e38\u7ec4\u7ec7\u7684\u6bd2\u6027\u3002Fraix\u7b49\u4eba\u5728\u5b8f\u89c2\u51dd\u80f6\u5f62\u6210\u4e2d\u540c\u65f6\u63ba\u5165\u4e86\u5149\u654f\u5242ZnPc\u548c\u4e00\u6c27\u5316\u6c2e\u7684\u5149\u4f9b\u4f53\uff0c\u5149\u7167\u4e0b\u53ef\u4ea7\u751f\u5355\u7ebf\u6001\u6c27\u548c\u4e00\u6c27\u5316\u6c2e\u4e24\u79cd\u6709\u6bd2\u7684\u7269\u8d28\uff0c\u6709\u671b\u7528\u4e8e\u6297\u764c\u548c\u6297\u83cc\uff08\u56fe3\uff09\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-86748 aligncenter\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2017\/06\/3-38.jpg\" alt=\"\" width=\"600\" height=\"557\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2017\/06\/3-38.jpg 600w, \/\/m.iemloyee.com\/wp-content\/uploads\/2017\/06\/3-38-300x279.jpg 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/p>\n<p><strong>\u56fe3 \uff08a\uff09<\/strong>\u4e00\u79cd\u5305\u88f9\u5149\u654f\u5242\u7684\u5b8f\u89c2\u51dd\u80f6\u7684\u5408\u6210\u65b9\u6cd5;<strong>\uff08b\uff09<\/strong>\u8be5\u5b8f\u89c2\u51dd\u80f6\u6210\u80f6\u524d\u540e\u7684\u7167\u7247\uff1b<strong>\uff08c\uff09<\/strong>\u5206\u522b\u7528470 nm\u548c650 nm\u7684\u5149\u7167\u5c04\u4e0b\u8be5\u51dd\u80f6\u7684\u7167\u7247\u56fe\uff08\u56fe\u7247\u6765\u6e90\uff1aFraix et al., J. Mater. Chem. B 2014, 2, 3443\uff09<\/p>\n<p><strong>2.3 \u57fa\u4e8e\u5b8f\u89c2\u51dd\u80f6\u7684\u5149\u52a8\u529b\u6297\u83cc\u7597\u6cd5<\/strong><\/p>\n<p>\u968f\u7740\u7ec6\u83cc\u8010\u836f\u6027\u7684\u4ea7\u751f\uff0c\u4f20\u7edf\u7684\u6297\u751f\u7d20\u5bf9\u7ec6\u83cc\u6740\u4f24\u6548\u679c\u660e\u663e\u4e0b\u964d\u3002\u800c\u5149\u52a8\u529b\u7597\u6cd5\u4e0d\u6613\u5f15\u8d77\u7ec6\u83cc\u7684\u8010\u836f\u6027\uff0c\u88ab\u8ba4\u4e3a\u662f\u4e00\u79cd\u53ef\u4ee5\u6709\u6548\u5bf9\u6297\u7ec6\u83cc\u611f\u67d3\u7684\u65b9\u6cd5\u3002\u540c\u6837\uff0c\u7531\u4e8e\u5149\u52a8\u529b\u6cbb\u7597\u6ca1\u6709\u9009\u62e9\u6027\uff0c\u5229\u7528\u5b8f\u89c2\u51dd\u80f6\u7684\u4f4e\u6d41\u52a8\u6027\uff0c\u65e2\u80fd\u591f\u4f7f\u5149\u654f\u5242\u957f\u65f6\u95f4\u6ede\u7559\u5728\u75c5\u7076\u533a\uff0c\u53c8\u53ef\u4ee5\u901a\u8fc7\u8c03\u8282\u5b8f\u89c2\u51dd\u80f6\u7684\u6027\u8d28\uff0c\u63a7\u5236\u5149\u654f\u5242\u5206\u5b50\u7684\u91ca\u653e\u901f\u7387\u3002<\/p>\n<p><strong>3. \u57fa\u4e8e\u6c34\u51dd\u80f6\u7684\u5149\u70ed\u7597\u6cd5<\/strong><\/p>\n<p>\u5728\u5149\u70ed\u6cbb\u7597\u4e2d\uff0c\u901a\u5e38\u4f7f\u7528\u5149\u70ed\u8bd5\u5242\u6765\u63d0\u9ad8\u75c5\u7076\u533a\u7684\u5347\u6e29\u6548\u679c\u3002\u6839\u636e\u75c5\u7076\u533a\u5347\u6e29\u7a0b\u5ea6\u7684\u4e0d\u540c\uff0c\u53ef\u5206\u4e3a\uff1a\u4e0d\u53ef\u9006\u7684\u635f\u4f24\u7597\u6cd5\uff08\u9ad8\u4e8e48\u2103\uff09\u3001\u9ad8\u70ed\u7597\u6cd5\uff0841\u201347\u2103\uff09\u548c\u4f4e\u70ed\u7597\u6cd5\uff08\u4f4e\u4e8e41\u2103\uff09\u3002\u4e0d\u53ef\u9006\u7684\u635f\u4f24\u7597\u6cd5\u80fd\u6709\u6548\u5f15\u8d77\u7ec6\u80de\u574f\u6b7b\uff0c\u4f46\u901a\u5e38\u7f3a\u4e4f\u9009\u62e9\u6027\uff1b\u9ad8\u70ed\u5904\u7406\u540e\uff0c\u7ec6\u80de\u5185\u7684\u751f\u5316\u53cd\u5e94\u901f\u5ea6\u5927\u5927\u63d0\u9ad8\uff0c\u5bfc\u81f4\u7ec6\u80de\u5185\u5206\u5b50\u6c27\u5316\u7a0b\u5ea6\u52a0\u5267\uff0c\u4f46\u8fd9\u4e00\u822c\u4e0d\u8db3\u4ee5\u6740\u6b7b\u7ec6\u80de\uff0c\u9700\u8981\u4e0e\u5176\u4ed6\u7597\u6cd5\u8054\u7528\uff1b\u4f4e\u70ed\u7597\u6cd5\u5bf9\u7ec6\u80de\u5f71\u54cd\u5c0f\uff0c\u4e3b\u8981\u7528\u4e8e\u7269\u7406\u7597\u6cd5\u4e2d\u3002\u6c34\u51dd\u80f6\u5728\u4e0d\u53ef\u9006\u7684\u635f\u4f24\u7597\u6cd5\u4e2d\uff0c\u53ef\u51cf\u5c11\u5149\u70ed\u5bf9\u6b63\u5e38\u7ec4\u7ec7\u7684\u635f\u4f24\uff0c\u540c\u65f6\u53ef\u5b9e\u73b0\u4e00\u6b21\u6ce8\u5c04\u591a\u6b21\u6cbb\u7597\u7684\u6548\u679c\uff08\u56fe4\uff09\uff1b\u5728\u9ad8\u70ed\u7597\u6cd5\u4e2d\uff0c\u53ef\u4f5c\u4e3a\u836f\u7269\u8f7d\u4f53\uff0c\u540c\u65f6\u643a\u5e26\u591a\u79cd\u836f\u7269\uff0c\u5b9e\u73b0\u8054\u5408\u6cbb\u7597\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-86749 aligncenter\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2017\/06\/4-27.jpg\" alt=\"\" width=\"600\" height=\"423\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2017\/06\/4-27.jpg 600w, \/\/m.iemloyee.com\/wp-content\/uploads\/2017\/06\/4-27-300x212.jpg 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/p>\n<p style=\"text-align: center;\"><strong>\u56fe4 \u53ef\u6ce8\u5c04\u6c34\u51dd\u80f6\u7528\u4e8e\u591a\u6b21\u5149\u70ed\u6cbb\u7597\u7684\u793a\u610f\u56fe\uff08\u56fe\u7247\u6765\u6e90\uff1aHsiao et al., Biomaterials 2015, 56, 26\uff09<\/strong><\/p>\n<p style=\"text-align: left;\"><strong>4. \u57fa\u4e8e\u6c34\u51dd\u80f6\u7684\u8054\u5408\u7597\u6cd5<\/strong><\/p>\n<p>\u4e0e\u5355\u72ec\u7597\u6cd5\u76f8\u6bd4\uff0c\u8054\u5408\u7597\u6cd5\u80fd\u591f\u4ea7\u751f\u534f\u540c\u6cbb\u7597\u7684\u6548\u679c\uff0c\u51cf\u5c11\u5355\u4e00\u836f\u7269\u7684\u4f7f\u7528\u5242\u91cf\uff0c\u540c\u65f6\u80fd\u6709\u6548\u6291\u5236\u8010\u836f\u6027\u7684\u4ea7\u751f\u3002\u800c\u6c34\u51dd\u80f6\u56e0\u4e3a\u80fd\u8f83\u4e3a\u5bb9\u6613\u5730\u5305\u88f9\u591a\u79cd\u836f\u7269\uff0c\u5e38\u7528\u4f5c\u8054\u5408\u7597\u6cd5\u7684\u836f\u7269\u8f7d\u4f53\u3002<\/p>\n<p><strong>4.1 \u5149\u52a8\u529b\u4e0e\u5149\u70ed\u8054\u5408\u7597\u6cd5<\/strong><\/p>\n<p>\u5149\u5728\u5149\u52a8\u529b\u6cbb\u7597\u548c\u5149\u70ed\u6cbb\u7597\u4e2d\u90fd\u9700\u8981\u4f7f\u7528\uff0c\u5982\u679c\u9009\u62e9\u4e00\u4e2a\u5408\u9002\u6ce2\u957f\u7684\u5149\u6fc0\u53d1\uff0c\u53ef\u4ee5\u4ee4\u5149\u654f\u5242\u548c\u5149\u70ed\u8bd5\u5242\u540c\u65f6\u53d1\u6325\u4f5c\u7528\u3002\u9664\u6b64\u4e4b\u5916\uff0c\u57fa\u4e8e\u6c34\u51dd\u80f6\u7684\u5149\u70ed\u548c\u5149\u52a8\u529b\u8054\u5408\u7597\u6cd5\u8fd8\u6709\u4ee5\u4e0b\u4f18\u52bf\uff1a\u9996\u5148\uff0c\u8054\u5408\u7597\u6cd5\u6bd4\u5355\u4e00\u7597\u6cd5\u7684\u6cbb\u7597\u6548\u679c\u597d\uff1b\u5176\u6b21\uff0c\u5229\u7528\u5149\u70ed\u6548\u5e94\u53ef\u4ee5\u8c03\u63a7\u6c34\u51dd\u80f6\u4e2d\u5149\u654f\u5242\u7684\u91ca\u653e\uff0c\u8fd8\u80fd\u589e\u52a0\u80bf\u7624\u533a\u57df\u7684\u901a\u900f\u6027\u548c\u6c27\u542b\u91cf\uff0c\u589e\u5f3a\u5149\u52a8\u529b\u6cbb\u7597\u7684\u6548\u679c\u3002Xing\u7b49\u4eba\u5728\u5b8f\u89c2\u51dd\u80f6\u4e2d\u540c\u65f6\u5f15\u5165\u5149\u654f\u5242\u548c\u5149\u70ed\u8bd5\u5242\uff0c\u4e0d\u4ec5\u589e\u52a0\u4e86\u836f\u7269\u7684\u6ede\u7624\u65f6\u95f4\uff0c\u800c\u4e14\u5149\u52a8\u529b\u548c\u5149\u70ed\u8054\u5408\u6cbb\u7597\u7684\u6548\u679c\u8981\u660e\u663e\u597d\u4e8e\u5355\u4e00\u6cbb\u7597\u7684\u6548\u679c\uff08\u56fe5\uff09\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-86750 aligncenter\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2017\/06\/5-18.jpg\" alt=\"\" width=\"600\" height=\"334\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2017\/06\/5-18.jpg 600w, \/\/m.iemloyee.com\/wp-content\/uploads\/2017\/06\/5-18-300x167.jpg 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/p>\n<p><strong>\u56fe5\uff08a-b\uff09<\/strong>\u7624\u5185\u6ce8\u5c04\u540e\uff0c\u8f7d\u6709\u5149\u654f\u5242\u548c\u5149\u70ed\u8bd5\u5242\u7684\u6c34\u51dd\u80f6\u7684\u836f\u7269\u91ca\u653e\u6bd4\u8f83\uff1b<strong>\uff08c-d\uff09<\/strong>\u4f53\u5185\u6291\u7624\u6548\u679c\u56fe\u3002\uff08\u56fe\u7247\u6765\u6e90\uff1aXing et al., Adv. Mater. 2016, 28, 3669\uff09<\/p>\n<p><strong>4.2 \u5149\u52a8\u529b\u548c\u5316\u7597\u8054\u5408\u7597\u6cd5<\/strong><\/p>\n<p>\u5149\u52a8\u529b\u7597\u6cd5\u548c\u5316\u7597\u90fd\u5bf9\u6b63\u5e38\u7ec4\u7ec7\u6709\u5f88\u5f3a\u7684\u6bd2\u526f\u4f5c\u7528\uff0c\u7528\u6c34\u51dd\u80f6\u4f5c\u4e3a\u836f\u7269\u8f7d\u4f53\uff0c\u53ef\u4ee5\u51cf\u5c11\u836f\u7269\u7684\u91ca\u653e\uff0c\u540c\u65f6\u5b9e\u73b0\u5c40\u90e8\u5149\u52a8\u529b\u548c\u5c40\u90e8\u5316\u7597\u7684\u6548\u679c\u3002<\/p>\n<p><strong>4.3 \u5149\u70ed\u4e0e\u5316\u7597\u8054\u5408\u7597\u6cd5<\/strong><\/p>\n<p>\u5982\u524d\u6587\u6240\u8ff0\uff0c\u9ad8\u70ed\u7597\u6cd5\u5e38\u7528\u4e8e\u8054\u5408\u7597\u6cd5\u4e2d\uff0c\u5c24\u5176\u662f\u4e0e\u5316\u7597\u8054\u7528\u3002\u9ad8\u70ed\u5904\u7406\u540e\u7684\u7ec6\u80de\u4e00\u822c\u5bf9\u5316\u7597\u836f\u7269\u7684\u654f\u611f\u7a0b\u5ea6\u63d0\u5347\uff0c\u56e0\u6b64\u53ef\u4ee5\u8f83\u5c11\u5316\u7597\u836f\u7269\u7684\u5242\u91cf\u3002\u540c\u65f6\uff0c\u4e00\u4e9b\u70ed\u54cd\u5e94\u7684\u6c34\u51dd\u80f6\u53ef\u8c03\u8282\u5316\u7597\u836f\u7269\u7684\u91ca\u653e\u901f\u7387\uff0c\u5b9e\u73b0\u53ef\u63a7\u836f\u7269\u91ca\u653e\u3002\u4f8b\u5982\uff0c\u7814\u7a76\u4eba\u5458\u5c06\u5177\u6709\u5149\u70ed\u6548\u5e94\u7684\u805a\u591a\u5df4\u80fa\u7eb3\u7c73\u9897\u7c92\u3001\u6297\u764c\u836f\u7269\u963f\u9709\u7d20\u548cbortezomib\uff08BTZ\uff09\u540c\u65f6\u5305\u88f9\u4e8e\u6c34\u51dd\u80f6\u4e2d\uff0c\u5229\u7528\u80bf\u7624\u533a\u57df\u7684\u5f31\u9178\u6027\u548c\u5149\u70ed\u53cc\u91cd\u54cd\u5e94\uff0c\u63a7\u5236\u836f\u7269\u91ca\u653e\uff08\u56fe6\uff09\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-86751 aligncenter\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2017\/06\/6-14.jpg\" alt=\"\" width=\"600\" height=\"320\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2017\/06\/6-14.jpg 600w, \/\/m.iemloyee.com\/wp-content\/uploads\/2017\/06\/6-14-300x160.jpg 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/p>\n<p style=\"text-align: center;\"><strong>\u56fe6 \u5229\u7528\u591a\u5df4\u80fa\u7eb3\u7c73\u9897\u7c92\u5149\u70ed\u7684\u6027\u8d28\uff0c\u63a7\u5236\u91ca\u653e\u6c34\u51dd\u80f6\u4e2d\u963f\u9709\u7d20\u7684\u793a\u610f\u56fe\u3002\uff08\u56fe\u7247\u6765\u6e90\uff1a GhavamiNejad et al., Sci. Rep. 2016, 6, 33594\uff09<\/strong><\/p>\n<p><strong>4.4 \u5176\u4ed6\u8054\u5408\u7597\u6cd5<\/strong><\/p>\n<p>\u7531\u4e8e\u75be\u75c5\u7684\u590d\u6742\u6027\uff0c\u6709\u4e9b\u75be\u75c5\u4ec5\u7528\u5355\u4e00\u7597\u6cd5\u5f88\u96be\u6709\u6548\u6cbb\u7597\uff0c\u6240\u4ee5\u901a\u5e38\u9700\u8981\u591a\u79cd\u7597\u6cd5\u540c\u65f6\u4f7f\u7528\u3002\u9664\u4e0a\u8ff0\u8054\u5408\u7597\u6cd5\u5916\uff0c\u6c34\u51dd\u80f6\u4f5c\u4e3a\u836f\u7269\u8f7d\u4f53\u5df2\u88ab\u8bc1\u660e\u53ef\u4e8e\u5149\u52a8\u529b\/\u5149\u70ed\u7597\u6cd5\/\u5316\u7597\u3001\u5149\u70ed\/\u57fa\u56e0\/\u5316\u7597\u7b49\u8054\u5408\u7597\u6cd5\u4e2d\u3002<\/p>\n<p><strong>5. \u603b\u7ed3\u4e0e\u5c55\u671b<\/strong><\/p>\n<p>\u7531\u4e8e\u5149\u7597\u6709\u4e00\u5b9a\u7684\u526f\u4f5c\u7528\uff0c\u6240\u4ee5\u8feb\u5207\u9700\u6c42\u5c40\u90e8\u6cbb\u7597\u7684\u65b9\u6cd5\u3002\u57fa\u4e8e\u6c34\u51dd\u80f6\u7684\u836f\u7269\u9012\u9001\u7cfb\u7edf\u662f\u5b9e\u73b0\u8fd9\u4e00\u76ee\u7684\u7684\u6709\u6548\u9014\u5f84\u3002\u5b8f\u89c2\u51dd\u80f6\u56e0\u4e3a\u5176\u56fa\u6709\u7684\u4f4e\u6d41\u52a8\u6027\uff0c\u53ef\u4ee5\u957f\u65f6\u95f4\u505c\u7559\u5728\u7279\u5b9a\u90e8\u4f4d\uff1b\u7eb3\u7c73\u51dd\u80f6\u7ee7\u627f\u4e86\u7eb3\u7c73\u9897\u7c92\u8f7d\u836f\u7684\u4f18\u52bf\uff0c\u5982\u9ad8\u6bd4\u8868\u9762\u79ef\u3001EPR\u6548\u5e94\u3001\u78c1\u6027\u548c\u8367\u5149\u6027\u8d28\u7b49\uff0c\u8d4b\u4e88\u8f7d\u836f\u4f53\u7cfb\u66f4\u591a\u7684\u6027\u8d28\u3002\u540c\u65f6\uff0c\u5b8f\u89c2\u51dd\u80f6\u548c\u7eb3\u7c73\u51dd\u80f6\u90fd\u53ef\u4ee5\u8f83\u4e3a\u5bb9\u6613\u5730\u5305\u88f9\u836f\u7269\uff0c\u5b9e\u73b0\u5355\u4e00\u6216\u591a\u79cd\u65b9\u5f0f\u7684\u6cbb\u7597\u3002\u5c3d\u7ba1\u5982\u6b64\uff0c\u6c34\u51dd\u80f6\u4f5c\u4e3a\u5149\u7597\u7684\u8f7d\u4f53\uff0c\u8fd8\u6709\u8bb8\u591a\u95ee\u9898\u9700\u8981\u89e3\u51b3\u3002\u9996\u5148\uff0c\u6c34\u51dd\u80f6\u5bf9\u5149\u654f\u5242\u4ea7\u751f\u5355\u7ebf\u6001\u6c27\u7684\u6548\u7387\u548c\u5149\u70ed\u8bd5\u5242\u4ea7\u70ed\u6548\u7387\u7684\u5f71\u54cd\u9700\u8981\u7814\u7a76\u3002\u4e3a\u4e86\u4e34\u5e8a\u9700\u6c42\uff0c\u9700\u8981\u4ece\u66f4\u591a\u89d2\u5ea6\u8bc4\u4ef7\u6c34\u51dd\u80f6\u7684\u751f\u7269\u5b89\u5168\u6027\u3002\u6700\u540e\uff0c\u5149\u7597\u5728\u6297\u83cc\u65b9\u9762\u6709\u7740\u72ec\u7279\u7684\u4f18\u52bf\uff0c\u4f46\u5229\u7528\u6c34\u51dd\u80f6\u7528\u4f5c\u5149\u7597\u6297\u83cc\u7684\u7814\u7a76\u8f83\u5c11\uff0c\u672a\u6765\u9700\u8981\u4f1a\u5728\u6b64\u65b9\u9762\u6709\u66f4\u591a\u7684\u7814\u7a76\u3002<\/p>\n<p><strong>\u6587\u732e\u94fe\u63a5\uff1a<a href=\"http:\/\/engine.scichina.com\/publisher\/scp\/journal\/SCMs\/doi\/10.1007\/s40843-017-9025-3?slug=full%20text\" target=\"_blank\" rel=\"noopener noreferrer\">Xiaodong Zhang, Liu-Yuan Xia, Xiaokai Chen, Zhan Chen*, Fu-Gen Wu*. Hydrogel-based phototherapy for fighting cancer and bacterial infection.<\/a><\/strong>\u00a0Science China Materials 2017, 60(6), 487\u2212503\uff0cDOI:10.1007\/s40843-017-9025-3<\/p>\n<p>\u672c\u6587\u7531\u5f20\u6653\u4e1c\u6295\u7a3f\uff0c\u6750\u6599\u4eba\u7f16\u8f91\u90e8\u5927\u57ce\u5c0f\u7231\u7f16\u8f91\u6574\u7406\u3002\u6750\u6599\u4eba\u7f51\u5c0a\u91cd\u6240\u6709\u8fdb\u884c\u77e5\u8bc6\u4f20\u64ad\u7684\u5a92\u4f53\uff0c\u5408\u4f5c\u8f6c\u8f7d\u8bf7\u8054\u7cfbtougao@cailiaoren.com\u3002<\/p>\n<p>\u6750\u6599\u725b\u7f51\u4e13\u6ce8\u4e8e\u8ddf\u8e2a\u6750\u6599\u9886\u57df\u79d1\u6280\u53ca\u884c\u4e1a\u8fdb\u5c55\uff0c\u8fd9\u91cc\u6c47\u96c6\u4e86\u5404\u5927\u9ad8\u6821\u7855\u535a\u751f\u3001\u4e00\u7ebf\u79d1\u7814\u4eba\u5458\u4ee5\u53ca\u884c\u4e1a\u4ece\u4e1a\u8005\uff0c\u5982\u679c\u60a8\u5bf9\u4e8e\u8ddf\u8e2a\u6750\u6599\u9886\u57df\u79d1\u6280\u8fdb\u5c55\uff0c\u89e3\u8bfb\u9ad8\u6c34\u5e73\u6587\u7ae0\u6216\u662f\u8bc4\u8ff0\u884c\u4e1a\u6709\u5174\u8da3\uff0c<a href=\"http:\/\/cailiaoren.mikecrm.com\/6qSdMU\" target=\"_blank\" rel=\"noopener noreferrer\">\u70b9\u6211\u52a0\u5165\u7f16\u8f91\u90e8<\/a>\u3002<\/p>\n<p><strong>\u6750\u6599\u6d4b\u8bd5\uff0c\u6570\u636e\u5206\u6790\uff0c\u4e0a<\/strong><a href=\"http:\/\/www.ceshigu.com\/\" target=\"_blank\" rel=\"noopener noreferrer\"><strong>\u6d4b\u8bd5\u8c37<\/strong><\/a><strong>\uff01<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u6750\u6599\u4eba\u9996\u5c4a\u79d1\u6280\u8d44\u8baf\u5199\u4f5c\u5927\u8d5b\u81ea5\u670813\u65e5\u53d1\u5e03\u5f81\u7a3f\u901a\u77e5\u4ee5\u6765\uff08\u53c2\u8d5b\u8be6\u60c5\u8bf7\u6233\u6211\uff09\uff0c\u53d7\u5230\u8bfb\u8005\u4eec\u7684\u5e7f\u6cdb\u5173\u6ce8\u3002\u53d7\u5230\u8bfb\u8005\u4eec\u7684\u5e7f\u6cdb\u5173\u6ce8\u3002\u611f\u8c22\u652f\u6301\u5355\u4f4dTaylor\u00a0&amp;\u00a0Fr&#8230;<\/p>\n","protected":false},"author":1369,"featured_media":86747,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[533],"tags":[],"class_list":["post-86743","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-zongshu"],"_links":{"self":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts\/86743"}],"collection":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/users\/1369"}],"replies":[{"embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=86743"}],"version-history":[{"count":3,"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts\/86743\/revisions"}],"predecessor-version":[{"id":92157,"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts\/86743\/revisions\/92157"}],"wp:featuredmedia":[{"embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/media\/86747"}],"wp:attachment":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=86743"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=86743"},{"taxonomy":"post_tag","embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=86743"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}