{"id":86455,"date":"2017-06-14T06:30:20","date_gmt":"2017-06-13T22:30:20","guid":{"rendered":"\/\/m.iemloyee.com\/?p=86455"},"modified":"2017-06-14T18:52:45","modified_gmt":"2017-06-14T10:52:45","slug":"sci-china-mater-%e5%87%ba%e7%89%88%e7%94%9f%e7%89%a9%e6%9d%90%e6%96%99%e7%bb%99%e8%8d%af%e7%b3%bb%e7%bb%9f%e4%b8%93%e5%88%8a","status":"publish","type":"post","link":"\/\/m.iemloyee.com\/?p=86455","title":{"rendered":"Sci. China Mater. \u51fa\u7248\u201c\u751f\u7269\u6750\u6599\u7ed9\u836f\u7cfb\u7edf\u201d\u4e13\u520a"},"content":{"rendered":"<p><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-86456 aligncenter\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2017\/06\/1-37.jpg\" alt=\"\" width=\"587\" height=\"782\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2017\/06\/1-37.jpg 587w, \/\/m.iemloyee.com\/wp-content\/uploads\/2017\/06\/1-37-225x300.jpg 225w\" sizes=\"(max-width: 587px) 100vw, 587px\" 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height=\"210\" \/><\/p>\n<p style=\"text-align: center;\"><strong>HasanUluda<\/strong><strong>\u011f<\/strong><strong>\u6559\u6388\uff0c\u52a0\u62ff\u5927\u963f\u5c14\u4f2f\u5854\u5927\u5b66<\/strong><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-86548 aligncenter\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2017\/06\/0-1-1.jpg\" alt=\"\" width=\"150\" height=\"210\" \/><\/p>\n<p style=\"text-align: center;\"><strong>\u987e\u5b81\u6559\u6388\uff0c\u4e1c\u5357\u5927\u5b66<\/strong><\/p>\n<p><span style=\"color: #ff0000;\"><strong>\u7efc\u8ff0\uff1a<\/strong><strong>\u57fa\u4e8e\u78c1\u6027\u8d28\u7684\u836f\u7269\u9012\u9001\u7cfb\u7edf<\/strong><\/span><\/p>\n<p>\u968f\u7740\u8fc7\u53bb\u51e0\u5341\u5e74\u6765\u751f\u7269\u533b\u5b66\u7eb3\u7c73\u6280\u672f\u548c\u7eb3\u7c73\u6750\u6599\u9886\u57df\u7684\u6301\u7eed\u53d1\u5c55\uff0c\u57fa\u4e8e\u7eb3\u7c73\u9897\u7c92\u7684\u836f\u7269\u8f93\u9001\u7cfb\u7edf\u9010\u6e10\u5f00\u59cb\u6709\u671b\u5e94\u7528\u4e8e\u4e34\u5e8a\u7814\u7a76\u3002\u5176\u4e2d\uff0c\u7531\u4e8e\u5177\u6709\u826f\u597d\u7684\u751f\u7269\u76f8\u5bb9\u6027\u548c\u4f18\u5f02\u7684\u591a\u529f\u80fd\u8d1f\u8f7d\u80fd\u529b\uff0c\u57fa\u4e8e\u78c1\u6027\u7eb3\u7c73\u7c92\u5b50\u7684\u78c1\u6027\u836f\u7269\u4f20\u9012\u7cfb\u7edf\u53d7\u5230\u8d8a\u6765\u8d8a\u591a\u7684\u5173\u6ce8\u3002<strong>\u4e1c\u5357\u5927\u5b66\u987e\u5b81\u6559\u6388\u548c\u6768\u82b3\u6559\u6388\u7b49<\/strong>\u603b\u7ed3\u4e86\u78c1\u6027\u836f\u7269\u4f20\u9012\u7cfb\u7edf\u7684\u57fa\u672c\u7269\u7406\u5316\u5b66\u6027\u8d28\uff0c\u4ee5\u9610\u660e\u78c1\u6027\u836f\u7269\u4f20\u9012\u7cfb\u7edf\u9700\u8981\u4fdd\u6301\u9002\u5f53\u7684\u6027\u80fd\u4ee5\u6ee1\u8db3\u7279\u5b9a\u7684\u4e34\u5e8a\u9700\u8981\uff1b\u8ba8\u8bba\u4e86\u5728\u8bbe\u8ba1\u672a\u6765\u4e34\u5e8a\u5e94\u7528\u7684\u78c1\u6027\u836f\u7269\u4f20\u9012\u7cfb\u7edf\u65f6\u7684\u8868\u9762\u4fee\u9970\u548c\u529f\u80fd\u5316\u95ee\u9898\uff1b\u5e76\u91cd\u70b9\u7efc\u8ff0\u4e86\u78c1\u6027\u7eb3\u7c73\u9897\u7c92\u3001\u78c1\u6027\u7ec4\u88c5\u4f53\u4ee5\u53ca\u78c1\u6027\u5fae\u6ce1\u3001\u78c1\u6027\u8102\u8d28\u4f53\u548c\u751f\u7269\u819c\u4fee\u9970\u7684\u78c1\u6027\u8f7d\u4f53\u7cfb\u7edf\u7684\u8bbe\u8ba1\u548c\u5236\u5907\u6700\u65b0\u8fdb\u5c55\u3002\u672c\u7efc\u8ff0\u5bf9\u76ee\u524d\u7814\u7a76\u7684\u78c1\u6027\u8f7d\u4f53\u7cfb\u7edf\u7684\u8bbe\u8ba1\u3001\u5236\u5907\u548c\u5b89\u5168\u6027\u8fdb\u884c\u4e86\u603b\u7ed3\uff0c\u5e76\u5bf9\u672a\u6765\u8fdb\u4e00\u6b65\u89e3\u51b3\u78c1\u6027\u836f\u7269\u4f20\u9012\u7cfb\u7edf\u7684\u4e34\u5e8a\u5e94\u7528\u74f6\u9888\u548c\u524d\u666f\u8fdb\u884c\u4e86\u5c55\u671b\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-86550 aligncenter\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2017\/06\/0-2-1.jpg\" alt=\"\" width=\"349\" height=\"367\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2017\/06\/0-2-1.jpg 349w, \/\/m.iemloyee.com\/wp-content\/uploads\/2017\/06\/0-2-1-285x300.jpg 285w\" sizes=\"(max-width: 349px) 100vw, 349px\" \/><\/p>\n<p style=\"text-align: center;\"><strong>\u8bbe\u8ba1\u78c1\u6027\u836f\u7269\u4f20\u9012\u7cfb\u7edf\u9700\u8981\u8bc4\u4f30\u7684\u56e0\u7d20<\/strong><\/p>\n<p><span style=\"color: #ff0000;\"><strong>\u7efc\u8ff0\uff1a\u57fa\u4e8e\u6c34\u51dd\u80f6\u7684\u5149\u7597\uff1a\u5bf9\u6297\u764c\u75c7\u548c\u7ec6\u83cc\u611f\u67d3<\/strong><\/span><\/p>\n<p>\u6c34\u51dd\u80f6\u6784\u6210\u4e86\u4e00\u7c7b\u7279\u6b8a\u7684\u9ad8\u5206\u5b50\u6750\u6599\uff0c\u5b83\u4eec\u7684\u4eb2\u6c34\u7ed3\u6784\u4f7f\u5f97\u5176\u80fd\u591f\u5728\u4e09\u7ef4\u7f51\u7edc\u4e2d\u4fdd\u6709\u5927\u91cf\u7684\u6c34\u3002\u5728\u8fc7\u53bb\u51e0\u5e74\u4e2d\uff0c\u6c34\u51dd\u80f6\u5728\u751f\u7269\u533b\u5b66\u9886\u57df\u7684\u5e94\u7528\u83b7\u5f97\u4e86\u5f88\u5927\u7684\u5173\u6ce8\uff0c\u5982\u4f5c\u4e3a\u836f\u7269\u6216\u7ec6\u80de\u7684\u8f7d\u4f53\u3001\u7ec4\u7ec7\u5de5\u7a0b\u548c\u751f\u7269\u4f20\u611f\u5668\u7b49\u3002\u7279\u522b\u5730\uff0c\u6c34\u51dd\u80f6\u4f5c\u4e3a\u836f\u7269\u8f93\u8fd0\u7cfb\u7edf\u5728\u5149\u7597\u4e2d\u6709\u7740\u663e\u8457\u4f18\u70b9\u3002<strong>\u5bc6\u6b47\u6839\u5927\u5b66\u5b89\u5a1c\u5821\u5206\u6821\u9648\u6218\u6559\u6388\u548c\u4e1c\u5357\u5927\u5b66\u5434\u5bcc\u6839\u6559\u6388\u7b49<\/strong>\u603b\u7ed3\u4e86\u6c34\u51dd\u80f6\u5728\u5149\u7597\u5e94\u7528\u4e2d\u7684\u6700\u65b0\u8fdb\u5c55\uff0c\u5c24\u5176\u91cd\u70b9\u8ba8\u8bba\u4e86\u4e09\u79cd\u5149\u7597\u65b9\u6cd5\uff08\u5305\u62ec\u5149\u52a8\u529b\u6cbb\u7597\u3001\u5149\u70ed\u6cbb\u7597\u548c\u7ec4\u5408\u6cbb\u7597\uff09\u53ca\u5176\u5728\u6297\u764c\u548c\u6297\u83cc\u9886\u57df\u7684\u5e94\u7528\u3002\u672c\u7efc\u8ff0\u5c06\u6709\u52a9\u4e8e\u542f\u53d1\u672a\u6765\u7684\u76f8\u5173\u7814\u7a76\u4ee5\u8fdb\u4e00\u6b65\u62d3\u5c55\u8fd9\u79cd\u6750\u6599\u5728\u5149\u7597\u9886\u57df\u7684\u65b0\u5e94\u7528.<\/p>\n<p style=\"text-align: center;\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-86551 aligncenter\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2017\/06\/0-3-1.jpg\" alt=\"\" width=\"616\" height=\"420\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2017\/06\/0-3-1.jpg 616w, \/\/m.iemloyee.com\/wp-content\/uploads\/2017\/06\/0-3-1-300x205.jpg 300w\" sizes=\"(max-width: 616px) 100vw, 616px\" \/><\/p>\n<p style=\"text-align: center;\"><strong>\u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0\u4ee5\u58f3\u805a\u7cd6\u884d\u751f\u7269\u6c34\u51dd\u80f6\u4e3a\u4f8b\u5c55\u793a\u5149\u7597\u7528\u4e8e\u6cbb\u7597\u764c\u75c7\u7684\u673a\u7406<\/strong>\u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0<\/p>\n<p><span style=\"color: #ff0000;\"><strong>\u7efc\u8ff0\uff1a\u7528\u4e8e\u80bf\u7624\u9776\u5411\u9012\u836f\u7684\u7ec6\u80de\u819c\u5305\u8986\u7eb3\u7c73\u7c92\u5b50<\/strong><\/span><\/p>\n<p>\u7531\u4e8eEPR\u6548\u5e94\uff0c\u7eb3\u7c73\u7c92\u5b50\u80fd\u591f\u5728\u80bf\u7624\u90e8\u4f4d\u6d53\u96c6\u5e76\u63d0\u9ad8\u8bb8\u591a\u5316\u7597\u836f\u7269\u7684\u6cbb\u7597\u6307\u6570\u3002\u4f20\u7edf\u7eb3\u7c73\u9012\u836f\u7cfb\u7edf\u7684\u8f7d\u4f53\u6750\u6599\u4e3b\u8981\u901a\u8fc7\u5316\u5b66\u5408\u6210\u65b9\u6cd5\u5236\u5907\uff0c\u800c\u76ee\u524d\u5c06\u5316\u5b66\u5408\u6210\u8f7d\u4f53\u4e0e\u5929\u7136\u4eff\u751f\u8f7d\u4f53\u76f8\u7ed3\u5408\u7684\u7b56\u7565\u5f97\u5230\u8d8a\u6765\u8d8a\u591a\u7684\u5173\u6ce8\u3002\u7ec6\u80de\u819c\u5305\u8986\u7eb3\u7c73\u7c92\u5b50\u4f5c\u4e3a\u65b0\u4e00\u4ee3\u4eff\u751f\u7eb3\u7c73\u5236\u5242\uff0c\u5c06\u7ec6\u80de\u819c\u7279\u6709\u7684\u751f\u7269\u5b66\u529f\u80fd\u4e0e\u5316\u5b66\u5408\u6210\u6750\u6599\u7684\u7406\u5316\u6027\u8d28\u76f8\u7ed3\u5408\uff0c\u5f62\u6210\u66f4\u6709\u6548\u7684\u9012\u836f\u7cfb\u7edf\u3002<strong>\u590d\u65e6\u5927\u5b66\u9646\u4f1f\u8dc3\u6559\u6388\u548c\u535a\u58eb\u751f\u67f4\u829d\u5170<\/strong>\u7b49\u5c31\u7ec6\u80de\u819c\u5305\u8986\u7eb3\u7c73\u7c92\u5b50\u7684\u957f\u5faa\u73af\u6548\u679c\u53ca\u4e3b\u52a8\u9776\u5411\u4f5c\u7528\u5728\u80bf\u7624\u9776\u5411\u6cbb\u7597\u4e2d\u7684\u7814\u7a76\u8fdb\u884c\u4e86\u603b\u7ed3\uff0c\u5e76\u5c31\u5176\u5728\u8111\u90e8\u80bf\u7624\u6cbb\u7597\u4e2d\u7684\u5e94\u7528\u524d\u666f\u8fdb\u884c\u4e86\u5c55\u671b\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-86552 aligncenter\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2017\/06\/0-4.jpg\" alt=\"\" width=\"467\" height=\"378\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2017\/06\/0-4.jpg 467w, \/\/m.iemloyee.com\/wp-content\/uploads\/2017\/06\/0-4-300x243.jpg 300w\" sizes=\"(max-width: 467px) 100vw, 467px\" \/><\/p>\n<p style=\"text-align: center;\"><strong>\u7ec6\u80de\u819c\u5305\u8986\u7eb3\u7c73\u7c92\u5b50\u5b9e\u73b0\u957f\u5faa\u73af\u6548\u679c\u53ca\u4e3b\u52a8\u9776\u5411\u4f5c\u7528\u7684\u7b56\u7565<\/strong><\/p>\n<p><span style=\"color: #ff0000;\"><strong>\u7efc\u8ff0\uff1a\u57fa\u56e0\u7f16\u8f91\u7cfb\u7edf\u975e\u75c5\u6bd2\u8f7d\u4f53\u7684\u7814\u7a76\u8fdb\u5c55<\/strong><\/span><\/p>\n<p>II\u578bCRISPR-Cas9\u7cfb\u7edf\u4e1a\u5df2\u6210\u4e3a\u4e00\u4e2a\u98ce\u9761\u751f\u7269\u6280\u672f\u9886\u57df\u7684\u57fa\u56e0\u7f16\u8f91\u7cfb\u7edf\u3002\u4f46\u5c06CRISPR-Cas9\u7f16\u8f91\u7cfb\u7edf\u76f4\u63a5\u7528\u4e8e\u6d3b\u4f53\u6765\u8fdb\u884c\u75be\u75c5\u6cbb\u7597\u4ecd\u53d7\u5230\u6765\u81ea\u9012\u9001\u8f7d\u4f53\u7684\u5236\u7ea6\u3002\u5927\u5206\u5b50\u91cf\u591a\u7ec4\u4efd\u7684\u9012\u8fd0\u76ee\u6807\u7269\uff0c\u52a0\u4e0a\u5411\u7ec6\u80de\u6838\u9012\u9001\u836f\u7269\u8fc7\u7a0b\u7684\u591a\u91cd\u751f\u7406\u5c4f\u969c\u4f7f\u5f97\u5728\u6d3b\u4f53\u4e2d\u5e94\u7528CRISPR-Cas9 \u9762\u4e34\u6311\u6218\u3002\u76ee\u524d\u4e3b\u6d41\u7684\u9012\u9001\u4f53\u7cfb\u662f\u75c5\u6bd2\u8f7d\u4f53\uff0c\u4f46\u662f\u51fa\u4e8e\u5bf9\u75c5\u6bd2\u8f7d\u4f53\u5b89\u5168\u6027\u7684\u8003\u8651\uff0c\u975e\u75c5\u6bd2\u7c7b\u8f7d\u4f53\u4e9f\u5f85\u5f00\u53d1\u3002<strong>\u5317\u5361\u7f57\u83b1\u7eb3\u5dde\u7acb\u5927\u5b66\u987e\u81fb\u526f\u6559\u6388\u548c\u535a\u58eb\u751f\u5b59\u68a7\u8fdb<\/strong>\u603b\u7ed3\u4e86\u6700\u8fd1\u5728CRISPR-Cas9\u975e\u75c5\u6bd2\u8f7d\u4f53\u7814\u7a76\u9886\u57df\u7684\u8fdb\u5c55\uff0c\u5e76\u5bf9\u5176\u6280\u672f\u96be\u70b9\u53ca\u672a\u6765\u53d1\u5c55\u65b9\u5411\u5c55\u5f00\u4e86\u8ba8\u8bba\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-86553 aligncenter\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2017\/06\/0-5.jpg\" alt=\"\" width=\"473\" height=\"293\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2017\/06\/0-5.jpg 473w, \/\/m.iemloyee.com\/wp-content\/uploads\/2017\/06\/0-5-300x186.jpg 300w\" sizes=\"(max-width: 473px) 100vw, 473px\" \/><\/p>\n<p style=\"text-align: center;\"><strong>\u57fa\u4e8eDNA\u7eb3\u7c73\u56e2\u7684\u8f7d\u4f53\u901a\u8fc7\u6838\u9178\u4e92\u8865\u4f5c\u7528\u8c03\u8282\u9012\u9001Cas9\/sgRNA\u6838\u7cd6\u6838\u86cb\u767d<\/strong><\/p>\n<p><span style=\"color: #ff0000;\"><strong>\u7814\u7a76\u8bba\u6587\uff1a\u758f\u6c34\u57fa\u53d6\u4ee3\u7684\u5206\u679d\u72b6\u805a\u4e59\u9170\u4e9a\u80fa\u884d\u751f\u7269<\/strong><strong>:<\/strong><strong>\u4fc3\u8fdb\u539f\u53d1\u6027\u8840\u7ba1\u7ec6\u80de\u4e2d\u7684\u8f6c\u67d3<\/strong><\/span><\/p>\n<p>\u9488\u5bf9\u8840\u7ba1\u7ec6\u80de\u7684\u57fa\u56e0\u6cbb\u7597\u4ee3\u8868\u4e86\u4e00\u79cd\u6709\u671b\u7528\u4e8e\u9884\u9632\u548c\u6cbb\u7597\u5185\u819c\u589e\u751f\u3001\u8840\u7ba1\u652f\u67b6\u72ed\u7a84\u548c\u8840\u7ba1\u6210\u5f62\u672f\u540e\u72ed\u7a84\u7b49\u75c5\u7406\u72b6\u6001\u7684\u65b9\u6cd5\u3002\u805a\u5408\u7269\u975e\u75c5\u6bd2\u8f7d\u4f53\u7684\u57fa\u56e0\u4f20\u9012\u7cfb\u7edf\u53ef\u4ee5\u5b89\u5168\u66ff\u4ee3\u75c5\u6bd2\u8f7d\u4f53\uff0c\u4f46\u662f\u4e3a\u4e86\u63d0\u9ad8\u4e34\u5e8a\u6548\u679c\uff0c\u5b83\u4eec\u7684\u6cbb\u7597\u6548\u7387\u53ca\u7ec6\u80de\u76f8\u5bb9\u6027\u8fd8\u9700\u8981\u8fdb\u4e00\u6b65\u6539\u5584\u3002<strong>\u52a0\u62ff\u5927\u963f\u5c14\u4f2f\u5854\u5927\u5b66<\/strong><strong>Hasan Uluda\u011f<\/strong><strong>\u6559\u6388\u548c\u62c9\u74e6\u5c14\u5927\u5b66<\/strong><strong>Daniele Pezzoli<\/strong><strong>\u535a\u58eb\u7b49<\/strong>\u5408\u6210\u4e86\u4e00\u7cfb\u5217\u88ab\u4e0d\u540c\u758f\u6c34\u57fa\u56e2\u4fee\u9970\u7684\u5206\u679d\u72b6\u805a\u4e59\u9170\u4e9a\u80fa\u884d\u751f\u7269(<em>b<\/em>PEI)\uff0c\u5e76\u5bf9\u5b83\u4eec\u8fdb\u884c\u4e86\u8868\u5f81\u53ca\u5728\u4f53\u5916\u539f\u53d1\u6027\u8840\u7ba1\u7ec6\u80de\u5185\u7684\u6d4b\u8bd5\uff0c\u65e8\u5728\u7b5b\u9009\u51fa\u5177\u6709\u4f18\u5f02\u7684\u8f6c\u67d3\u6548\u7387\u548c\u4f4e\u7ec6\u80de\u6bd2\u6027\u7684\u4f20\u9012\u5242\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-86554 aligncenter\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2017\/06\/0-6.jpg\" alt=\"\" width=\"400\" height=\"405\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2017\/06\/0-6.jpg 400w, \/\/m.iemloyee.com\/wp-content\/uploads\/2017\/06\/0-6-296x300.jpg 296w\" sizes=\"(max-width: 400px) 100vw, 400px\" \/><\/p>\n<p style=\"text-align: center;\"><strong>\u758f\u6c34\u57fa\u53d6\u4ee3\u7684\u5206\u679d\u72b6\u805a\u4e59\u9170\u4e9a\u80fa\u884d\u751f\u7269\u4f5c\u4e3a\u57fa\u56e0\u8f7d\u4f53\u8f6c\u67d3\u539f\u53d1\u6027\u8840\u7ba1\u7ec6\u80de<\/strong><\/p>\n<p><span style=\"color: #ff0000;\"><strong>\u7814\u7a76\u8bba\u6587\uff1a<a style=\"color: #ff0000;\" name=\"OLE_LINK2\"><\/a><a style=\"color: #ff0000;\" name=\"OLE_LINK1\"><\/a>\u591a\u5b54\u65b9\u89e3\u77f3\u76f8\u78b3\u9178\u9499\u5fae\u7403\u7684\u81ea\u7ec4\u88c5\u5408\u6210\u53ca\u53e3\u8154\u4fee\u590d\u5e94\u7528<\/strong><\/span><\/p>\n<p>\u591a\u5b54\u78b3\u9178\u9499\u5fae\u7403\u7684\u5f31\u6c34\u6eb6\u6db2\u7a33\u5b9a\u6027\u548c\u4f4e\u518d\u77ff\u5316\u901f\u7387\u9650\u5236\u4e86\u5176\u5728\u751f\u7269\u533b\u836f\u9886\u57df\u7684\u5e94\u7528\u3002\u4e3a\u4e86\u89e3\u51b3\u8be5\u95ee\u9898\uff0c<strong>\u4e0a\u6d77\u7845\u9178\u76d0\u6240\u9648\u822a\u6995\u6559\u6388\u548c\u9a6c\u660e\u526f\u6559\u6388<\/strong>\u7b49\u901a\u8fc7\u201c\u6c14\u4f53\u6269\u6563-\u9648\u5316\u201d\u4e24\u6b65\u7b56\u7565\u5236\u5907\u4e86\u5177\u6709\u5927\u5b54\u7ed3\u6784\u548c\u65b9\u89e3\u77f3\u76f8\u7684\u78b3\u9178\u9499\u5fae\u7403\u6750\u6599\u3002\u8be5\u5408\u6210\u7b56\u7565\u53cd\u5e94\u6761\u4ef6\u6e29\u548c\uff0c\u540c\u65f6\u4e0d\u9700\u8981\u4f7f\u7528\u6a21\u677f\u5242\u548c\u6676\u578b\u5bfc\u5411\u5242\uff0c\u80fd\u591f\u786e\u4fdd\u5fae\u7403\u4ea7\u7269\u7684\u751f\u7269\u5b89\u5168\u6027\u3002\u6240\u5236\u5907\u7684\u78b3\u9178\u9499\u5fae\u7403\u53ef\u4ee5\u5438\u9644\u5927\u91cf\u7684\u514d\u75ab\u7403\u86cb\u767dIgY\uff0c\u5e76\u8868\u73b0\u51fa\u589e\u5f3a\u6291\u5236\u53e3\u8154\u53d8\u5f62\u94fe\u7403\u83cc\u7684\u80fd\u529b\u3002\u6b64\u5916\uff0c\u7814\u7a76\u663e\u793a\u8be5\u5fae\u7403\u53ef\u4ee5\u5728\u6c34\u6eb6\u6db2\u4e2d\u4fdd\u6301\u8f83\u9ad8\u7684\u7ed3\u6784\u7a33\u5b9a\u6027\uff0c\u800c\u5728\u4eba\u4f53\u4f53\u6db2\u548c\u553e\u6db2\u73af\u5883\u4e2d\u5feb\u901f\u518d\u77ff\u5316\u5e76\u8f6c\u53d8\u6210\u7f9f\u57fa\u78f7\u7070\u77f3\u7ed3\u6784\uff0c\u5bf9\u7259\u672c\u8d28\u5c0f\u7ba1\u5177\u6709\u8f83\u4f73\u7684\u5c01\u95ed\u6548\u679c\uff0c\u4e3a\u5176\u7528\u4e8e\u6cbb\u7597\u7259\u672c\u8d28\u8fc7\u654f\u75c7\u63d0\u4f9b\u4e86\u4f9d\u636e\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-86555\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2017\/06\/0-7.jpg\" alt=\"\" width=\"634\" height=\"177\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2017\/06\/0-7.jpg 634w, \/\/m.iemloyee.com\/wp-content\/uploads\/2017\/06\/0-7-300x84.jpg 300w\" sizes=\"(max-width: 634px) 100vw, 634px\" \/><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-86556 aligncenter\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2017\/06\/0-8.jpg\" alt=\"\" width=\"467\" height=\"236\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2017\/06\/0-8.jpg 467w, \/\/m.iemloyee.com\/wp-content\/uploads\/2017\/06\/0-8-300x152.jpg 300w\" sizes=\"(max-width: 467px) 100vw, 467px\" \/><\/p>\n<p style=\"text-align: center;\"><strong>\u591a\u5b54\u65b9\u89e3\u77f3\u76f8\u78b3\u9178\u9499\u5fae\u7403\u7684\u81ea\u7ec4\u88c5\u5408\u6210\u53ca\u5176\u7259\u9f7f\u4fee\u590d\u8fc7\u7a0b\u793a\u610f\u56fe<\/strong><\/p>\n<p><span style=\"color: #ff0000;\"><strong>\u7814\u7a76\u8bba\u6587\uff1a\u57fa\u4e8e\u4e73\u6db2\u5fae\u6d41\u63a7\u6280\u672f\u7684\u6838\u58f3\u7ed3\u6784\u590d\u5408\u5fae\u80f6\u56ca\u836f\u7269\u8f7d\u4f53\u5f00\u53d1\u7814\u7a76<\/strong><\/span><\/p>\n<p>\u5fae\u80f6\u56ca\u5728\u836f\u7269\u9012\u9001\u7cfb\u7edf\u4e2d\u5177\u6709\u91cd\u8981\u7684\u5e94\u7528\u4ef7\u503c\u3002<strong>\u4e1c\u5357\u5927\u5b66\u8d75\u8fdc\u9526\u6559\u6388\u8bfe\u9898\u7ec4<\/strong>\u63d0\u51fa\u4e86\u4e00\u79cd\u53ef\u534f\u540c\u8fd0\u8f93\u548c\u7f13\u6162\u91ca\u653e\u836f\u7269\u7684\u5fae\u80f6\u56ca\uff0c\u5176\u7531\u660e\u80f6\u7532\u57fa\u4e19\u70ef\u9178\u63a5\u679d\u5171\u805a\u7269(GelMa)\u5185\u6838\u548c\u805a\u4e73\u9178\u7f9f\u57fa\u4e59\u9178\u5171\u805a\u7269(PLGA)\u5916\u58f3\u7ec4\u6210\u3002\u5728\u5fae\u80f6\u56ca\u7684\u5236\u5907\u8fc7\u7a0b\u4e2d\uff0c\u53ef\u5206\u522b\u5728\u5185\u6838\u548c\u58f3\u5c42\u4e2d\u5305\u88f9\u4e0d\u540c\u7684\u836f\u7269\uff0c\u5b9e\u73b0\u534f\u540c\u7ed9\u836f\u3002\u8be5\u8fc7\u7a0b\u907f\u514d\u4e86\u4e73\u6db2\u7684\u7834\u635f\u53ca\u5305\u88f9\u6db2\u7684\u6d41\u51fa\uff0c\u56e0\u6b64\u53ef\u663e\u8457\u63d0\u9ad8\u836f\u7269\u7684\u5305\u88f9\u6548\u7387\u3002\u7531\u4e8e\u6240\u5236\u5907\u7684\u5fae\u80f6\u56ca\u5185\u6838\u548c\u5916\u58f3\u90fd\u4e3a\u56fa\u5316\u72b6\u6001\uff0c\u5176\u5305\u88f9\u7684\u6d3b\u6027\u836f\u7269\u53ea\u80fd\u968f\u7740\u8f7d\u4f53\u6750\u6599\u7684\u964d\u89e3\u800c\u7f13\u6162\u91ca\u653e\u51fa\u6765\uff0c\u8fd9\u5c31\u907f\u514d\u4e86\u5176\u4ed6\u79cd\u7c7b\u836f\u7269\u8f7d\u4f53\u6240\u9762\u4e34\u7684\u836f\u7269\u7a81\u91ca\u73b0\u8c61\u3002\u672c\u7814\u7a76\u6240\u5f00\u53d1\u7684\u5fae\u80f6\u56ca\u7684\u8fd9\u4e9b\u4f18\u826f\u7279\u6027\u4f7f\u5176\u6210\u4e3a\u836f\u7269\u9012\u9001\u7cfb\u7edf\u4e2d\u7684\u7406\u60f3\u9009\u62e9\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-86557 aligncenter\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2017\/06\/0-9.jpg\" alt=\"\" width=\"555\" height=\"312\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2017\/06\/0-9.jpg 555w, \/\/m.iemloyee.com\/wp-content\/uploads\/2017\/06\/0-9-300x169.jpg 300w\" sizes=\"(max-width: 555px) 100vw, 555px\" \/><\/p>\n<p style=\"text-align: center;\"><strong>\u4e73\u6db2\u5fae\u6d41\u63a7\u6280\u672f\u5236\u5907\u6838\u58f3\u7ed3\u6784\u590d\u5408\u5fae\u80f6\u56ca\u836f\u7269\u8f7d\u4f53\u7684\u8fc7\u7a0b\u793a\u610f\u56fe<\/strong><\/p>\n<p><span style=\"color: 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\/\/m.iemloyee.com\/wp-content\/uploads\/2017\/06\/0-12-300x71.jpg 300w\" sizes=\"(max-width: 650px) 100vw, 650px\" \/><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-86560 aligncenter\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2017\/06\/0-13.jpg\" alt=\"\" width=\"642\" height=\"238\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2017\/06\/0-13.jpg 642w, \/\/m.iemloyee.com\/wp-content\/uploads\/2017\/06\/0-13-300x111.jpg 300w\" sizes=\"(max-width: 642px) 100vw, 642px\" \/><\/p>\n<p style=\"text-align: center;\"><strong>\u5e72\u6270\u7d20<\/strong><strong>-\u03b1<\/strong><strong>\u7684<\/strong><strong>C<\/strong><strong>\u672b\u7aef\u539f\u4f4d\u805a\u5408<\/strong><strong>POEGMA<\/strong><strong>\u793a\u610f\u56fe\u53ca\u5176\u4f53\u5185\u6297\u80bf\u7624\u6548\u679c<\/strong><\/p>\n<p><strong>\u539f\u6587\u94fe\u63a5<\/strong><strong>http:\/\/engine.scichina.com\/publisher\/scp\/journal\/SCMs\/60\/6?slug=Browse<\/strong><\/p>\n<p><em>Science China 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