{"id":78735,"date":"2017-05-08T06:30:47","date_gmt":"2017-05-07T22:30:47","guid":{"rendered":"\/\/m.iemloyee.com\/?p=78735"},"modified":"2017-05-06T18:07:21","modified_gmt":"2017-05-06T10:07:21","slug":"%e8%92%8b%e5%85%b4%e5%ae%87nat-commun-%ef%bc%9a%e9%87%91%e7%ba%b3%e7%b1%b3%e5%9b%a2%e7%b0%87%e8%be%85%e5%8a%a9%e9%80%92%e9%80%81ngf-sirna%e7%94%a8%e4%ba%8e%e8%83%b0%e8%85%ba%e7%99%8c%e6%b2%bb","status":"publish","type":"post","link":"\/\/m.iemloyee.com\/?p=78735","title":{"rendered":"\u848b\u5174\u5b87Nat. Commun.\uff1a\u91d1\u7eb3\u7c73\u56e2\u7c07\u8f85\u52a9\u9012\u9001NGF siRNA\u7528\u4e8e\u80f0\u817a\u764c\u6cbb\u7597"},"content":{"rendered":"

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\u3010\u6210\u679c\u7b80\u4ecb\u3011<\/strong><\/p>\n

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\u3010\u56fe\u6587\u5bfc\u8bfb\u3011<\/strong><\/p>\n

\u56fe1 GNCs\u548cGNC-siRNA\u590d\u5408\u7269\u7684XPS\u5206\u6790<\/strong><\/p>\n

\"\"<\/p>\n

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\u56fe2\u00a0GNC-siRNA\u4f53\u5916\u8868\u5f81<\/strong><\/p>\n

\"\"<\/p>\n

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\uff08b\uff09\u6e38\u79bbsiRNA\u548cGNC-siRNA\u8fdb\u5165Panc-1\u7ec6\u80de\u7684\u7ec6\u80de\u6444\u53d6<\/p>\n

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\"\"<\/p>\n

\uff08a\uff09\u6e38\u79bbsiRNA\u548cGNC-siRNA\u590d\u5408\u7269\u5728\u8840\u6db2\u4e2d\u7684\u5faa\u73af\u65f6\u95f4<\/p>\n

\uff08b\uff09\u4f53\u5185\u80bf\u7624\u9776\u5411<\/p>\n

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\uff08e\uff09\u901a\u8fc7ICP-MS\u6ce8\u5c04GNC-siRNA\u590d\u5408\u7269\u540e6\u5c0f\u65f6\u548c24\u5c0f\u65f6\u540e\uff0c\u4e3b\u8981\u5668\u5b98\u548c\u80bf\u7624\u4e2d\u7684\u91d1\u6d53\u5ea6\uff08\u4ee5\u7ed9\u5b9a\u5242\u91cf\u7684\u767e\u5206\u6570\u8868\u793a\uff09<\/p>\n

\u56fe4\u00a0GNC-siRNA\u590d\u5408\u7269\u5728\u76ae\u4e0b\u80f0\u817a\u80bf\u7624\u4e2d\u7684\u6297\u80bf\u7624\u6548\u5e94\u548c\u57fa\u56e0\u6291\u5236\u4f5c\u7528<\/strong><\/p>\n

\"\"<\/p>\n

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\uff08d\uff09NGF mRNA\u7684\u8868\u8fbe\u6c34\u5e73\u548c\uff08e\uff09\u76ae\u4e0b\u80bf\u7624\u4e2dNGF\u86cb\u767d\u6c34\u5e73<\/p>\n

\uff08f\uff09\u7ecf\u4e0d\u540csiRNA\u5904\u7406\u7684\u80bf\u7624\u7ec4\u7ec7\u4e2d\u7684\u795e\u7ecf\u7a81\u7684IF\u67d3\u8272<\/p>\n

\u56fe5\u00a0GNC-siRNA\u590d\u5408\u7269\u5bf9\u80f0\u817a\u764c\u6cbb\u7597\u7684\u9012\u9001\u673a\u5236<\/strong><\/p>\n

\"\"<\/p>\n

GNC-siRNA\u590d\u5408\u7269\u4fdd\u62a4NGF siRNA\u514d\u53d7\u8840\u6e05\u6838\u9178\u9176\u964d\u89e3\uff0c\u589e\u5f3aNGF siRNA\u5bf9\u80bf\u7624\u7ec6\u80de\u7684\u79ef\u7d2f\uff0c\u4f7f\u5f97\u80f0\u817a\u80bf\u7624\u4e2d\u6709\u6548\u7684\u6291\u5236NGF<\/p>\n

\u3010\u603b\u7ed3\u3011<\/strong><\/p>\n

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\u6587\u732e\u94fe\u63a5<\/strong>\uff1aGold nanoclusters-assisted delivery of NGF siRNA for effective treatment of pancreatic cancer<\/a>\uff08Nat. Commun., 2017, \u00a0DOI:10.1038\/ncomms15130)<\/p>\n

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