{"id":74116,"date":"2017-04-01T12:42:40","date_gmt":"2017-04-01T04:42:40","guid":{"rendered":"\/\/m.iemloyee.com\/?p=74116"},"modified":"2017-04-01T12:48:44","modified_gmt":"2017-04-01T04:48:44","slug":"%e5%8c%97%e4%ba%ac%e7%a7%91%e6%8a%80%e5%a4%a7%e5%ad%a6%e7%b2%be%e5%87%86%e5%8c%bb%e7%96%97%e4%b8%8e%e5%81%a5%e5%ba%b7%e7%a0%94%e7%a9%b6%e9%99%a2%e6%88%90%e7%ab%8b%ef%bc%8c%e8%af%ba%e5%a5%96%e5%be%97","status":"publish","type":"post","link":"\/\/m.iemloyee.com\/?p=74116","title":{"rendered":"\u5317\u4eac\u79d1\u6280\u5927\u5b66\u7cbe\u51c6\u533b\u7597\u4e0e\u5065\u5eb7\u7814\u7a76\u9662\u6210\u7acb\uff0c\u8bfa\u5956\u5f97\u4e3b\u52a0\u76df\uff0c\u53ef\u7a7f\u6234\u4f20\u611f\u5668\u7814\u7a76\u5165\u9009"},"content":{"rendered":"<p>\u6628\u65e5\uff0c\u5317\u4eac\u79d1\u6280\u5927\u5b66\u7cbe\u51c6\u533b\u7597\u4e0e\u5065\u5eb7\u7814\u7a76\u9662\u6b63\u5f0f\u6302\u724c\u6210\u7acb\u3002\u8be5\u7814\u7a76\u9662\u4ee5\u56fd\u9645\u548c\u56fd\u5185\u9876\u5c16\u7684\u76f8\u5173\u79d1\u7814\u4eba\u5458\u4e3a\u7814\u7a76\u56e2\u961f\uff0c\u9488\u5bf9\u7cbe\u51c6\u533b\u7597\u9886\u57df\u5b58\u5728\u7684\u8bf8\u591a\u91cd\u5927\u5173\u952e\u79d1\u6280\u95ee\u9898\uff0c\u5b9e\u65bd\u7cbe\u51c6\u533b\u5b66\u7814\u7a76\u7684\u5168\u521b\u65b0\u94fe\u534f\u540c\u653b\u5173\uff0c\u4ee5\u671f\u5b9e\u73b0\u80bf\u7624\u75be\u75c5\u7684\u7cbe\u51c6\u533b\u7597\u3002<\/p>\n<p>\u8be5\u9662\u4e0b\u8bbe\u516d\u4e2a\u7814\u7a76\u4e2d\u5fc3\uff0c\u5206\u522b\u7531\u56fd\u9645\u77e5\u540d\u5b66\u8005\u51fa\u4efb\u4e2d\u5fc3\u4e3b\u4efb\uff1a<\/p>\n<ul>\n<li>\u6590\u91cc\u5fb7\u533b\u5b66\u7814\u7a76\u4e2d\u5fc3\uff1a\u8bfa\u8d1d\u5c14\u751f\u7406\u5b66\u6216\u533b\u5b66\u5956\u83b7\u5f97\u8005<strong>\u6590\u91cc\u5fb7\u00b7<\/strong><strong>\u7a46\u62c9\u5fb7\uff08<\/strong><strong>Ferid Murad<\/strong><strong>\uff09<\/strong><\/li>\n<li>\u7f57\u4f2f\u7279\u836f\u7269\u7814\u7a76\u4e2d\u5fc3\uff1a\u7f8e\u56fd\u9ebb\u7701\u7406\u5de5\u5b66\u9662\u6559\u6388<strong>\u7f57\u4f2f\u7279\u00b7<\/strong><strong>\u5170\u683c\uff08<\/strong><strong>Robert Langer<\/strong><strong>\uff09<\/strong><\/li>\n<li>\u7ea6\u745f\u592b\u53ef\u7a7f\u6234\u5f0f\u4f20\u611f\u5668\u7814\u7a76\u4e2d\u5fc3:\u7f8e\u56fd\u52a0\u5dde\u5927\u5b66\u5723\u5730\u4e9a\u54e5\u5206\u6821\u6559\u6388<strong>\u7ea6\u745f\u592b\u00b7<\/strong><strong>\u738b\uff08<\/strong><strong>Joseph Wang<\/strong><strong>\uff09<\/strong><\/li>\n<li>\u5fb7\u7c73\u7279\u91cc\u7cbe\u51c6\u6cbb\u7597\u7814\u7a76\u4e2d\u5fc3\uff1a\u5168\u7403\u767e\u5f3a\u8457\u540d\u764c\u75c7\u5916\u79d1\u4e13\u5bb6<strong>\u5fb7\u7c73\u7279\u91cc\u00b7<\/strong><strong>\u5965\u5c14\u767b\uff08<\/strong><strong>Dmitri Alden<\/strong><strong>\uff09<\/strong><\/li>\n<li>\u5317\u4eac\u7cbe\u51c6\u8bca\u65ad\u533b\u5b66\u7814\u7a76\u4e2d\u5fc3\uff1a\u5317\u4eac\u79d1\u6280\u5927\u5b66\u751f\u7269\u5de5\u7a0b\u4e0e\u4f20\u611f\u6280\u672f\u4e2d\u5fc3\u4e3b\u4efb<strong>\u5f20\u5b66\u8bb0<\/strong><\/li>\n<li>\u5317\u4eac\u836f\u7269\u4e0e\u5065\u5eb7\u7814\u7a76\u4e2d\u5fc3\uff1a\u5317\u4eac\u79d1\u6280\u5927\u5b66\u5316\u5b66\u4e0e\u751f\u7269\u5de5\u7a0b\u5b66\u9662\u7279\u5c97\u6559\u6388<strong>\u4e07\u5411\u5143<\/strong><\/li>\n<\/ul>\n<p>\u636e\u6089\uff0c\u5317\u4eac\u79d1\u6280\u5927\u5b66\u5c06\u4e0e\u53d7\u8058\u4e13\u5bb6\u5728\u764c\u75c7\u7cbe\u51c6\u6cbb\u7597\u836f\u7269\u6750\u6599\u7814\u53d1\u3001\u4e00\u6c27\u5316\u6c2e\u4fe1\u606f\u4f20\u9012\u7cfb\u7edf\u3001\u7eb3\u7c73\u673a\u5668\u4eba\u548c\u7535\u5316\u5b66\u751f\u7269\u4f20\u611f\u5668\u7b49\u65b9\u9762\u5c55\u5f00\u5168\u9762\u800c\u7d27\u5bc6\u7684\u5408\u4f5c\u3002\u6b64\u5916\uff0c\u5916\u7c4d\u4e13\u5bb6\u6bcf\u5e74\u8fd8\u4f1a\u9080\u8bf7\u6570\u540d\u56fd\u9645\u7cbe\u51c6\u533b\u7597\u7814\u7a76\u9886\u57df\u7684\u77e5\u540d\u4e13\u5bb6\u548c\u5b66\u8005\u6765\u6821\u8bb2\u5b66\uff0c\u5e76\u4e3a\u7814\u7a76\u9662\u7684\u7814\u7a76\u4eba\u5458\u548c\u7814\u7a76\u751f\u5230\u56fd\u5916\u4ea4\u6d41\u3001\u8fdb\u4fee\u3001\u53c2\u52a0\u56fd\u9645\u6027\u5b66\u672f\u4f1a\u8bae\u521b\u9020\u6761\u4ef6\uff0c\u63d0\u4f9b\u673a\u4f1a\uff0c\u5f62\u6210\u5e38\u89c4\u5316\u7684\u56fd\u9645\u4ea4\u6d41\u5408\u4f5c\u5173\u7cfb\u3002\u53cc\u65b9\u8fd8\u5c06\u6574\u5408\u56fd\u9645\u4e0a\u7814\u7a76\u3001\u4eba\u529b\u8d44\u6e90\u4ee5\u6253\u9020\u690d\u6839\u4e8e\u5317\u4eac\u79d1\u6280\u5927\u5b66\u56fd\u9645\u9ad8\u6c34\u5e73\u7684\u7cbe\u51c6\u533b\u7597\u7814\u7a76\u56e2\u961f\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-74117  aligncenter\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2017\/04\/WeChat-Image_20170331180106-1024x768.jpg\" alt=\"\" width=\"598\" height=\"449\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2017\/04\/WeChat-Image_20170331180106-1024x768.jpg 1024w, \/\/m.iemloyee.com\/wp-content\/uploads\/2017\/04\/WeChat-Image_20170331180106-300x225.jpg 300w, \/\/m.iemloyee.com\/wp-content\/uploads\/2017\/04\/WeChat-Image_20170331180106-768x576.jpg 768w\" sizes=\"(max-width: 598px) 100vw, 598px\" \/><\/p>\n<p style=\"text-align: center\">Ferid Murad\u5728\u5317\u4eac\u79d1\u6280\u5927\u5b66\u53c2\u52a0\u201c\u7406\u5b66\u4e4b\u7f8e\u201d\u540d\u5e08\u8bb2\u575b\u5e76\u83b7\u8d60\u201c\u6c42\u5b9e\u9f0e\u65b0\u201d\u5317\u79d1\u6821\u8bad\u4e66\u6cd5\u4f5c\u54c1<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-74118  aligncenter\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2017\/04\/WeChat-Image_20170331180124-1024x768.jpg\" alt=\"\" width=\"599\" height=\"449\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2017\/04\/WeChat-Image_20170331180124-1024x768.jpg 1024w, \/\/m.iemloyee.com\/wp-content\/uploads\/2017\/04\/WeChat-Image_20170331180124-300x225.jpg 300w, \/\/m.iemloyee.com\/wp-content\/uploads\/2017\/04\/WeChat-Image_20170331180124-768x576.jpg 768w, \/\/m.iemloyee.com\/wp-content\/uploads\/2017\/04\/WeChat-Image_20170331180124.jpg 1280w\" sizes=\"(max-width: 599px) 100vw, 599px\" \/><\/p>\n<p>\u4e13\u5bb6\u5ea7\u8c08\uff08\u4ece\u5de6\u81f3\u53f3\uff09\uff1aFerid Murad, \u5f20\u5b66\u8bb0, Joseph Wang, Dmitri Alden, \u5b59\u9e3f\uff08Dmitri Alden\u7ecf\u7eaa\u4eba\uff09<\/p>\n<p><span style=\"color: #ff0000\"><strong>\u3010\u53d7\u8058\u4e13\u5bb6\u7b80\u4ecb\u3011<\/strong><\/span><\/p>\n<p><span style=\"color: #0000ff\"><strong>\u6590\u91cc\u5fb7<\/strong><strong>\u00b7<\/strong><strong>\u7a46\u62c9\u5fb7\uff08<\/strong><strong>Ferid Murad<\/strong><strong>\uff09<\/strong><\/span><\/p>\n<p>1936\u5e749\u6708\u51fa\u751f\uff0c\u533b\u751f\u548c\u836f\u7406\u5b66\u5bb6\uff0c1998\u5e74\u8bfa\u8d1d\u5c14\u751f\u7406\u5b66\u6216\u533b\u5b66\u5956\u5f97\u4e3b\u4e4b\u4e00\u3002\u7f8e\u56fd\u56fd\u5bb6\u79d1\u5b66\u9662\u3001\u56fd\u5bb6\u533b\u5b66\u79d1\u5b66\u9662\u548c\u827a\u672f\u4e0e\u79d1\u5b66\u9662\u4e09\u9662\u9662\u58eb\uff0c2007\u5e74\u83b7\u8058\u4e3a\u4e2d\u56fd\u79d1\u5b66\u9662\u5916\u7c4d\u9662\u58eb\u3002Murad\u6559\u6388\u957f\u671f\u4ece\u4e8b\u7ec6\u80de\u4fe1\u53f7\u7814\u7a76\uff0c\u5176\u7814\u7a76\u5de5\u4f5c\u4e3b\u8981\u96c6\u4e2d\u5728\u4e00\u6c27\u5316\u6c2e\u4fe1\u606f\u4f20\u9012\u7cfb\u7edf\u7814\u7a76\u9886\u57df\uff0c\u5e76\u5f00\u8f9f\u4e86\u4e00\u6c27\u5316\u6c2e\u75c5\u7406\u5b66\u53ca\u708e\u75c7\u533b\u5b66\u7684\u65b0\u65b9\u5411\uff0c\u4ee5\u4fc3\u8fdb\u65b0\u6cbb\u7597\u624b\u6bb5\u7684\u53d1\u73b0\u548c\u53d1\u5c55\u3002<\/p>\n<p><span style=\"color: #0000ff\"><strong>\u7f57\u4f2f\u7279<\/strong><strong>\u00b7<\/strong><strong>\u5170\u683c\uff08<\/strong><strong>Robert Langer<\/strong><strong>\uff09<\/strong><\/span><\/p>\n<p>\u7f8e\u56fd\u79d1\u5b66\u5bb6\uff0c\u751f\u7269\u5de5\u7a0b\u5b66\u8005\uff0c\u9ebb\u7701\u7406\u5de5\u5b66\u9662\uff08MIT\uff09\u7684\u6234\u7ef4\u00b7H\u00b7\u79d1\u514b\u5b66\u9662\u6559\u6388\u3002\u7ec4\u7ec7\u5de5\u7a0b\u548c\u836f\u7269\u91ca\u653e\u7814\u7a76\u7684\u5148\u9a71\uff0c\u7f8e\u56fd\u6700\u5e74\u8f7b\u7684\u201c\u4e09\u9662\u9662\u58eb\u201d\uff08\u533b\u5b66\u7814\u7a76\u9662\u3001\u5de5\u7a0b\u9662\u548c\u79d1\u5b66\u9662\uff09\uff0c \u88ab\u300a\u798f\u5e03\u65af\u300b\u7b49\u5a92\u4f53\u8bc4\u4e3a\u5168\u7403\u751f\u7269\u6280\u672f\u9886\u57df\u6700\u6709\u5f71\u54cd\u7684\u4eba\u7269\u4e4b\u4e00\u3002\u53d1\u8868\u5b66\u672f\u8bba\u6587\u903e\u5343\u7bc7\uff0c\u62e5\u6709\u8d85\u8fc7800\u4e2a\u4e13\u5229\u3002\u8fd9\u4e9b\u4e13\u5229\u6388\u6743\u7ed9\u4e86\u8d85\u8fc7250\u4e2a\u5236\u836f\u3001\u5316\u5b66\u3001\u751f\u7269\u6280\u672f\u548c\u533b\u5b66\u4eea\u5668\u516c\u53f8\u3002\u5170\u683c\u6559\u6388\u662f\u8fc4\u4eca\u88ab\u5f15\u7528\u6b21\u6570\u6700\u591a\u7684\u5de5\u7a0b\u5b66\u5bb6\u5e76\u4e8e2008\u5e74\u83b7\u82ac\u5170\u201c\u5343\u5e74\u6280\u672f\u5956\u201d\u3002<\/p>\n<p><span style=\"color: #0000ff\"><strong>\u7ea6\u745f\u592b<\/strong><strong>\u00b7<\/strong><strong>\u738b\uff08<\/strong><strong>Joseph Wang<\/strong><strong>\uff09<\/strong><\/span><\/p>\n<p>\u7f8e\u56fd\u52a0\u5dde\u5927\u5b66\u5723\u5730\u4e9a\u54e5\u5206\u6821\uff08UCSD\uff09\u7eb3\u7c73\u5de5\u7a0b\u5b66\u7cfb\u7279\u8058\u6559\u6388\u548c\u4e3b\u4efb\u3001\u53ef\u7a7f\u6234\u5f0f\u4f20\u611f\u5668\u4e2d\u5fc3\u4e3b\u4efb\uff0c\u53ef\u7a7f\u6234\u6280\u672f\u7814\u7a76\u9886\u57df\u7684\u56fd\u9645\u9876\u5c16\u4e13\u5bb6\u3002\u5df2\u53d1\u8868\u8d85\u8fc7980\u7bc7\u7814\u7a76\u8bba\u6587\uff0c\u62e5\u670935\u9879\u4e13\u5229\uff0c\u64b0\u519912\u672c\u4e13\u8457\uff0c\u53c2\u4e0e\u7f16\u519940\u591a\u672c\u8457\u4f5c\u3002\u7f8e\u56fd\u533b\u5b66\u4e0e\u751f\u7269\u5de5\u7a0b\u9662\u9662\u58eb\uff0c\u82f1\u56fd\u7687\u5bb6\u5316\u5b66\u4f1a\u4f1a\u58eb\u3002\u7814\u7a76\u9886\u57df\uff1a\u7eb3\u7c73\u751f\u7269\u7535\u5b50\u5b66\u548c\u7eb3\u7c73\u673a\u68b0\uff0c\u5305\u62ec\u7eb3\u7c73\u751f\u7269\u6280\u672f\u3001\u7eb3\u7c73\u6750\u6599\u4e3a\u57fa\u7840\u7684\u4f20\u611f\u5668\u3001\u7eb3\u7c73\u53d1\u52a8\u673a\u548c\u7eb3\u7c73\u5236\u52a8\u5668\u3001\u7eb3\u7c73\u7c92\u5b50\u6807\u8bb0\u6269\u589e\/\u590d\u7528\u751f\u7269\u68c0\u6d4b\u3001\u7eb3\u7c73\u6761\u5f62\u7801\u3001\u7eb3\u7c73\u836f\u7269\u3001DNA\u548c\u86cb\u767d\u8d28\u7684\u8bca\u65ad\u3001\u8fdc\u7a0b\u4f20\u611f\u5668\u3001\u7eb3\u7c73\u4f20\u611f\u5668\u548c\u751f\u7269\u533b\u5b66\u7b49\u3002<\/p>\n<p><span style=\"color: #0000ff\"><strong>\u5fb7\u7c73\u7279\u91cc\u00b7\u5965\u5c14\u767b\uff08<\/strong><strong>Dmitri Alden<\/strong><strong>\uff09<\/strong><\/span><\/p>\n<p>\u5168\u7403\u8457\u540d\u764c\u75c7\u5916\u79d1\u4e13\u5bb6\uff0c\u4f5c\u4e3a\u809d\u764c\u3001\u80c6\u9053\u764c\u3001\u80f0\u817a\u764c\u3001\u5375\u5de2\u764c\u7b49\u9886\u57df\u7684\u4e13\u5bb6\uff0c\u5728\u809d\u80c6\u5916\u79d1\u624b\u672f\u548c\u809d\u79fb\u690d\u6709\u7740\u5927\u91cf\u4e34\u5e8a\u7ecf\u9a8c\u3002\u88ab\u7f8e\u56fd\u6d88\u8d39\u8005\u7814\u7a76\u59d4\u5458\u4f1a\u8bc4\u4e3a\u7f8e\u56fd100\u5f3a\u5916\u79d1\u533b\u751f\uff0c\u83b7\u7f8e\u56fd\u5916\u79d1\u533b\u5e08\u5b66\u9662\uff08FACS\uff09\u8363\u8a89\u5956\u3002\u5176\u7814\u7a76\u9886\u57df\u4e3a\u809d\u764c\u53ca\u5176\u5b83\u764c\u75c7\u5916\u79d1\u4e2a\u4f53\u5316\u8bca\u7597\u65b9\u6848\uff0c\u81f4\u529b\u4e8e\u7cbe\u51c6\u533b\u7597\u521b\u65b0\u524d\u6cbf\u6280\u672f\u7814\u7a76\uff0c\u4ee5\u56fd\u9645\u6700\u5148\u8fdb\u7684\u624b\u672f\u548c\u6280\u672f\u5bfb\u6c42\u6cbb\u6108\u590d\u6742\u764c\u75c7\u7684\u6700\u4f73\u65b9\u6848\u3002<\/p>\n<p><span style=\"color: #0000ff\"><strong>\u5f20\u5b66\u8bb0<\/strong><\/span><\/p>\n<p>\u4f20\u611f\u5668\u9886\u57df\u4e13\u5bb6\uff0c\u56fd\u5bb6\u201c\u5343\u4eba\u8ba1\u5212\u201d\u7279\u8058\u6559\u6388\u3002\u73b0\u4efb\u5317\u4eac\u79d1\u6280\u5927\u5b66\u5316\u5b66\u4e0e\u751f\u7269\u5de5\u7a0b\u5b66\u9662\u9662\u957f\u3001\u6559\u6388\u3001\u535a\u58eb\u751f\u5bfc\u5e08\u3002\u56fd\u5bb6\u81ea\u7136\u79d1\u5b66\u57fa\u91d1\u59d4\u5458\u4f1a\u91cd\u5927\u7814\u7a76\u8ba1\u5212\u9879\u76ee\u6d77\u5916\u8bc4\u59d4\u59d4\u5458\uff0c\u5317\u4eac\u5e02\u653f\u5e9c\u7279\u8058\u987e\u95ee\u4e13\u5bb6\uff0c\u65e5\u672c\u4e1c\u4eac\u5927\u5b66\u6559\u6388\u3001\u540d\u53e4\u5c4b\u5927\u5b66\u6559\u6388\uff0cNIH\u3001NSF\u3001\u6b27\u76df\u57fa\u91d1\u3001\u65b0\u52a0\u5761\u56fd\u5bb6\u5956\u548c\u7f8e\u56fd\u4e2d\u5c0f\u4f01\u4e1a\u521b\u65b0\u5956\u8bc4\u59d4\u3002\u62c5\u4efb<em>Am. J. of Biomed. 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