{"id":72066,"date":"2017-03-22T06:30:16","date_gmt":"2017-03-21T22:30:16","guid":{"rendered":"\/\/m.iemloyee.com\/?p=72066"},"modified":"2017-03-19T21:52:10","modified_gmt":"2017-03-19T13:52:10","slug":"angew-chem-int-ed-%e5%8f%91%e8%89%b2%e5%9b%a2%e5%85%b1%e8%bd%ad%e7%9a%84%e4%b8%8a%e8%bd%ac%e6%8d%a2%e7%ba%b3%e7%b1%b3%e9%a2%97%e7%b2%92%e5%ae%9e%e6%97%b6%e7%9b%91%e6%8e%a7%e4%bd%93%e5%86%85","status":"publish","type":"post","link":"\/\/m.iemloyee.com\/?p=72066","title":{"rendered":"Angew. Chem. Int. Ed.: \u53d1\u8272\u56e2\u5171\u8f6d\u7684\u4e0a\u8f6c\u6362\u7eb3\u7c73\u9897\u7c92\u5b9e\u65f6\u76d1\u63a7\u4f53\u5185\u7684\u809d\u6bd2\u6027"},"content":{"rendered":"<p><strong>\u3010\u80cc\u666f\u7b80\u4ecb\u3011<\/strong><\/p>\n<p>\u836f\u7269\u8bf1\u5bfc\u7684\u809d\u635f\u4f24\u662f\u73b0\u4ee3\u533b\u7597\u7684\u4e00\u5927\u96be\u9898\u3002\u6251\u70ed\u606f\u75db\uff08APAP\uff09\u662f\u4e00\u79cd\u5e38\u7528\u7684\u6297\u75db\/\u6297\u9ad8\u70e7\u7684\u836f\u7269\uff0c\u4f46\u662f\u5f53APAP\u8fc7\u91cf\u4f7f\u7528\u65f6\u7531\u4e8e\u4ea7\u751f\u6d3b\u6027\u6c2e\uff08RNS\uff09\u800c\u4f1a\u5bfc\u81f4\u4e25\u91cd\u7684\u809d\u6bd2\u6027\u3002ONOO<sup>&#8211;<\/sup>\u662fRNS\u4e2d\u7684\u4e00\u79cd\uff0c\u53ef\u4ee5\u4f5c\u4e3a\u809d\u6bd2\u6027\u7684\u751f\u7269\u6807\u8bb0\u7269\u3002\u4f46\u662fONOO<sup>&#8211;<\/sup>\u7684\u5bff\u547d\u5f88\u77ed\uff0c\u5728\u4f53\u5185\u76d1\u63a7\u5b83\u4eec\u5f88\u56f0\u96be\u3002<\/p>\n<p><strong>\u3010\u6210\u679c\u7b80\u4ecb\u3011<\/strong><\/p>\n<p>\u6700\u8fd1<strong>\u4e2d\u56fd\u836f\u79d1\u5927\u5b66\u7684Juanjuan Peng\u3001\u6e56\u5357\u5927\u5b66\u7684\u8881\u6797\u3001\u65b0\u52a0\u5761\u56fd\u7acb\u5927\u5b66\u7684\u5218\u5c0f\u521a\u548cYoung-Tae Chang\uff08\u5171\u540c\u901a\u8baf\u4f5c\u8005\uff09<\/strong>\u7b49\u4eba\u7528\u805a\u4e59\u70ef\u4e9a\u80fa\u8986\u76d6\u6838-\u58f3\u7ed3\u6784\u7684\u4e0a\u8f6c\u6362\u7eb3\u7c73\u9897\u7c92\u7684\u8868\u9762\uff0c\u7136\u540e\u518d\u5171\u8f6d\u9752\u8272\u7d20\uff08Cy7\uff09\u3002\u4e0a\u8f6c\u6362\u7eb3\u7c73\u9897\u7c92\u80fd\u5438\u6536980nm\u7684\u6fc0\u5149\u800c\u53d1\u51fa800nm\u7684\u8367\u5149\uff0c\u5f53Cy7\u5b58\u5728\u4e8e\u8868\u9762\u65f6\uff0c\u5b83\u53ef\u4ee5\u5438\u6536800nm\u7684\u8367\u5149\u3002\u9047\u5230ONOO<sup>&#8211;<\/sup>\u65f6\uff0cCy7\u88ab\u5206\u88c2\u6210\u4e24\u90e8\u5206\uff0c\u4e0d\u80fd\u518d\u5438\u6536\u8367\u5149\uff0c\u8fd9\u65f6\u6574\u4e2a\u7eb3\u7c73\u9897\u7c92\u53ef\u4ee5\u53d1\u51fa\u8367\u5149\uff0c\u4e14\u8367\u5149\u7684\u5f3a\u5ea6\u968fONOO<sup>&#8211;<\/sup>\u7684\u542b\u91cf\u7684\u589e\u52a0\u800c\u589e\u5f3a\u3002\u8fd9\u79cd\u7eb3\u7c73\u9897\u7c92\u7684\u751f\u7269\u76f8\u5bb9\u6027\u597d\uff0c\u5728\u4f53\u5185\u7a33\u5b9a\uff0c\u4e14\u5bf9\u5176\u5b83\u7684\u6d3b\u6027\u6c27\/\u6c2e\u4e0d\u654f\u611f\uff0c\u53ef\u4ee5\u5728\u4f53\u5916\u548c\u4f53\u5185\u5bf9RNs\u8fdb\u884c\u76d1\u63a7\u3002<\/p>\n<p><strong>[\u81f4\u6b49\uff1a\u5c0f\u7f16\u672a\u80fd\u627e\u5230\u901a\u8baf\u4f5c\u8005Juanjuan Peng\u548cYoung-Tae Chang\u7684\u786e\u5207\u4e2d\u6587\u540d\u5b57\uff0c\u5728\u6b64\u8868\u793a\u8bda\u631a\u7684\u6b49\u610f\uff01]<\/strong><\/p>\n<p><strong>\u3010\u56fe\u6587\u5bfc\u8bfb\u3011<\/strong><\/p>\n<p><strong>\u56fe1 \u7eb3\u7c73\u9897\u7c92\u7684\u8bbe\u8ba1\u53ca\u4f5c\u7528\u673a\u7406<\/strong><\/p>\n<p><a href=\"\/\/m.iemloyee.com\/?attachment_id=72067\" rel=\"attachment wp-att-72067\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-72067\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2017\/03\/\u56fe\u72471-15.jpg\" alt=\"\" width=\"700\" height=\"395\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2017\/03\/\u56fe\u72471-15.jpg 700w, \/\/m.iemloyee.com\/wp-content\/uploads\/2017\/03\/\u56fe\u72471-15-300x169.jpg 300w\" sizes=\"(max-width: 700px) 100vw, 700px\" \/><\/a><\/p>\n<p>\uff08a\uff09\u7eb3\u7c73\u9897\u7c92\u7684\u8bbe\u8ba1\uff1b<\/p>\n<p>\uff08b\uff09Cy7\u5728ONOO-\u6216ClO-\u4f5c\u7528\u4e0b\u5206\u88c2\u7684\u53ef\u80fd\u673a\u7406<\/p>\n<p>\uff08c\uff09\u5728ONOO-\u4e0d\u5b58\u5728\uff08\u7eff\u7ebf\uff09\u6216\u5b58\u5728\uff08\u7ea2\u7ebf\uff09\u65f6Cy7\u7684\u7d2b\u5916\/\u53ef\u89c1\u5438\u6536\u5149\u8c31\uff0c\u7d2b\u7ebf\u4e3a980nm\u6fc0\u5149\u7167\u5c04\u4e0b\u4e0a\u8f6c\u6362\u7eb3\u7c73\u9897\u7c92\u7684\u53d1\u5c04\u5149\u8c31\uff1b<\/p>\n<p>\uff08d\uff09APAP\u8bf1\u5bfc\u4ea7\u751f\u809d\u6bd2\u6027\u7684\u673a\u5236<\/p>\n<p><strong>\u56fe2\u7eb3\u7c73\u9897\u7c92\u7684\u6027\u80fd\u8868\u5f81<\/strong><\/p>\n<p><a href=\"\/\/m.iemloyee.com\/?attachment_id=72068\" rel=\"attachment wp-att-72068\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-72068\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2017\/03\/\u56fe\u72472-11.jpg\" alt=\"\" width=\"700\" height=\"339\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2017\/03\/\u56fe\u72472-11.jpg 700w, \/\/m.iemloyee.com\/wp-content\/uploads\/2017\/03\/\u56fe\u72472-11-300x145.jpg 300w\" sizes=\"(max-width: 700px) 100vw, 700px\" \/><\/a><\/p>\n<p>\uff08a\uff09\u7eb3\u7c73\u9897\u7c92\u4fee\u9970Cy7\u524d\u548c\u540e\u7684800nm\u8367\u5149\u4fe1\u53f7\uff0c\u63d2\u56fe\u4e3a\u4fee\u9970\u524d\u548c\u540e\u7684\u6eb6\u6db2\u989c\u8272\u5bf9\u6bd4\uff1b<\/p>\n<p>\uff08b\uff09\u7eb3\u7c73\u9897\u7c92\u4fee\u9970Cy7\u524d\u548c\u540e\u7684\u8367\u5149\u5bff\u547d\uff1b<\/p>\n<p>\uff08c\uff09HeLa \u7ec6\u80de\u5728\u4e0d\u540c\u6d53\u5ea6\u7684\u7eb3\u7c73\u9897\u7c92\u4e2d\u57f9\u517b24h\u540e\u7684\u5b58\u6d3b\u7387\uff1b<\/p>\n<p>\uff08d\uff09\u7eb3\u7c73\u9897\u7c92\u7684\u8367\u5149\u54cd\u5e94\u4e0eONOO<sup>&#8211;<\/sup>\u6d53\u5ea6\u7684\u5173\u7cfb\uff0c\u63d2\u56fe\u662f\u76f8\u5e94\u6eb6\u6db2\u7684\u989c\u8272\u53d8\u5316\uff1b<\/p>\n<p>\uff08e\uff09800nm\u8367\u5149\u5f3a\u5ea6\u4e0eONOO<sup>&#8211;<\/sup>\u6d53\u5ea6\u7684\u5173\u7cfb\u66f2\u7ebf\uff1b<\/p>\n<p>\uff08f\uff09\u9010\u6e10\u6dfb\u52a0ONOO<sup>&#8211;<\/sup>\u65f6\u67d3\u6599\uff08Cy7\uff09\u7684\u5438\u6536\u5149\u8c31\uff0c\u63d2\u56fe\u662f\u5438\u6536\u5f3a\u5ea6\u4e0eONOO<sup>&#8211;<\/sup>\u6d53\u5ea6\u7684\u5173\u7cfb\u66f2\u7ebf<\/p>\n<p><strong>\u56fe3 \u7eb3\u7c73\u9897\u7c92\u7528\u4e8e\u4f53\u5185\u68c0\u6d4b\u809d\u6bd2\u6027<\/strong><\/p>\n<p><a href=\"\/\/m.iemloyee.com\/?attachment_id=72069\" rel=\"attachment wp-att-72069\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-72069\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2017\/03\/\u56fe\u72473-8.jpg\" alt=\"\" width=\"700\" height=\"276\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2017\/03\/\u56fe\u72473-8.jpg 700w, \/\/m.iemloyee.com\/wp-content\/uploads\/2017\/03\/\u56fe\u72473-8-300x118.jpg 300w\" sizes=\"(max-width: 700px) 100vw, 700px\" \/><\/a><\/p>\n<p>\uff08a\uff09\u7eb3\u7c73\u9897\u7c92\u5bf9PBS\u7f13\u51b2\u6db2\u6216\u4e0d\u540c\u6d53\u5ea6\u836f\u7269\uff08500, 250 mg kg<sup>-1<\/sup>\uff09\u6cbb\u7597\u540e\u7684\u8001\u9f20\u6210\u50cf\u7684\u4ee3\u8868\u56fe\u50cf\uff0c\u6fc0\u53d1\u6ce2\u957f\u4e3a980nm\uff0c\u6d4b\u91cf\u7684\u6ce2\u957f\u4e3a790\u00b140nm\uff1b<\/p>\n<p>\uff08b\uff09\u6263\u9664\u80cc\u5e95\u540e\u809d\u810f\u533a\u57df\u7684\u8367\u5149\u5f3a\u5ea6\u968f\u65f6\u95f4\u7684\u53d8\u5316\uff08\u6ce8\u5c04\u7eb3\u7c73\u9897\u7c92\u540e\u5f00\u59cb\u8ba1\u65f6\uff09<\/p>\n<p><strong>\u3010\u603b\u7ed3\u4e0e\u5c55\u671b\u3011<\/strong><\/p>\n<p>\u4f5c\u8005\u8bbe\u8ba1\u4e86\u4e00\u79cd\u7528\u4e8e\u5feb\u901f\u3001\u7075\u654f\u68c0\u6d4bONOO-\u7684\u63a2\u9488\uff0c\u8be5\u63a2\u9488\u7684\u68c0\u6d4b\u6781\u9650\u4f4e\u81f30.08\u03bcM\uff0c\u54cd\u5e94\u65f6\u95f4\u7ea6\u4e3a1s\u3002\u5229\u7528\u8be5\u63a2\u9488\u4f5c\u8005\u63a2\u6d4b\u5230\u4e86\u52a8\u7269\u6a21\u578b\u4e2dAPAP\u8bf1\u5bfc\u4ea7\u751f\u7684RNS\uff0c\u8fd9\u79cd\u63a2\u9488\u6709\u671b\u7528\u4e8e\u5feb\u901f\u786e\u5b9a\u65b0\u578b\u836f\u7269\u7684\u809d\u6bd2\u6027\u3002<\/p>\n<p><strong>\u6587\u732e\u94fe\u63a5<\/strong>\uff1a<a href=\"http:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/anie.201612020\/full\" target=\"_blank\">Real-Time In\u2005Vivo Hepatotoxicity Monitoring Through Chromophore-Conjugated Photon-Upconverting Nanoprobes<\/a>\uff08Angew. Chem. Int. Ed., 2017, DOI:10.1002\/anie.201612020\uff09<\/p>\n<p>\u672c\u6587\u7531\u6750\u6599\u4eba\u751f\u7269\u6750\u6599\u7ec4\u9648\u662d\u94ed\u4f9b\u7a3f\uff0c\u6750\u6599\u725b\u7f16\u8f91\u6574\u7406\u3002<\/p>\n<p>\u53c2\u4e0e\u751f\u7269\u6750\u6599\u8bdd\u9898\u8ba8\u8bba\u6216\u4e86\u89e3\u751f\u7269\u6750\u6599\u5c0f\u7ec4\u62db\u52df\u8be6\u60c5\uff0c\u8bf7\u52a0\u5165\u6750\u6599\u4eba\u751f\u7269\u6750\u6599\u4ea4\u6d41\u7fa4\uff08124806506\uff09\u3002<\/p>\n<p>\u6750\u6599\u725b\u7f51\u4e13\u6ce8\u4e8e\u8ddf\u8e2a\u6750\u6599\u9886\u57df\u79d1\u6280\u53ca\u884c\u4e1a\u8fdb\u5c55\uff0c\u8fd9\u91cc\u6c47\u96c6\u4e86\u5404\u5927\u9ad8\u6821\u7855\u535a\u751f\u3001\u4e00\u7ebf\u79d1\u7814\u4eba\u5458\u4ee5\u53ca\u884c\u4e1a\u4ece\u4e1a\u8005\uff0c\u5982\u679c\u60a8\u5bf9\u4e8e\u8ddf\u8e2a\u6750\u6599\u9886\u57df\u79d1\u6280\u8fdb\u5c55\uff0c\u89e3\u8bfb\u9ad8\u6c34\u5e73\u6587\u7ae0\u6216\u662f\u8bc4\u8ff0\u884c\u4e1a\u6709\u5174\u8da3\uff0c<a href=\"\/\/m.iemloyee.com\/25127.html\" target=\"_blank\">\u70b9\u6211\u52a0\u5165\u7f16\u8f91\u90e8<\/a>\u3002<\/p>\n<p><strong>\u6750\u6599\u6d4b\u8bd5\uff0c\u6570\u636e\u5206\u6790\uff0c\u4e0a<\/strong><a href=\"http:\/\/www.ceshigu.com\/\" target=\"_blank\"><strong>\u6d4b\u8bd5\u8c37<\/strong><\/a><strong>\uff01<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u3010\u80cc\u666f\u7b80\u4ecb\u3011 \u836f\u7269\u8bf1\u5bfc\u7684\u809d\u635f\u4f24\u662f\u73b0\u4ee3\u533b\u7597\u7684\u4e00\u5927\u96be\u9898\u3002\u6251\u70ed\u606f\u75db\uff08APAP\uff09\u662f\u4e00\u79cd\u5e38\u7528\u7684\u6297\u75db\/\u6297\u9ad8\u70e7\u7684\u836f\u7269\uff0c\u4f46\u662f\u5f53APAP\u8fc7\u91cf\u4f7f\u7528\u65f6\u7531\u4e8e\u4ea7\u751f\u6d3b\u6027\u6c2e\uff08RNS\uff09\u800c\u4f1a\u5bfc\u81f4&#8230;<\/p>\n","protected":false},"author":382,"featured_media":72067,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[215],"tags":[75],"class_list":["post-72066","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-jiedu","tag-biomaterial"],"_links":{"self":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts\/72066"}],"collection":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/users\/382"}],"replies":[{"embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=72066"}],"version-history":[{"count":8,"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts\/72066\/revisions"}],"predecessor-version":[{"id":72215,"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts\/72066\/revisions\/72215"}],"wp:featuredmedia":[{"embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/media\/72067"}],"wp:attachment":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=72066"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=72066"},{"taxonomy":"post_tag","embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=72066"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}