{"id":65689,"date":"2017-02-20T06:30:11","date_gmt":"2017-02-19T22:30:11","guid":{"rendered":"\/\/m.iemloyee.com\/?p=65689"},"modified":"2017-03-18T21:47:10","modified_gmt":"2017-03-18T13:47:10","slug":"acc-chem-res-%e7%bb%bc%e8%bf%b0%ef%bc%9a%e5%88%86%e6%9e%90%e7%89%a9%e5%93%8d%e5%ba%94%e5%9e%8b%e6%b0%b4%e5%87%9d%e8%83%b6%ef%bc%9a%e7%94%a8%e4%ba%8e%e7%94%9f%e7%89%a9%e4%bc%a0%e6%84%9f%e5%92%8c","status":"publish","type":"post","link":"\/\/m.iemloyee.com\/?p=65689","title":{"rendered":"Acc. Chem. Res.\u7efc\u8ff0\uff1a\u5206\u6790\u7269\u54cd\u5e94\u578b\u6c34\u51dd\u80f6\uff1a\u7528\u4e8e\u751f\u7269\u4f20\u611f\u548c\u836f\u7269\u8f93\u9001\u7684\u667a\u80fd\u6750\u6599"},"content":{"rendered":"

\u3010\u5f15\u8a00\u3011<\/strong><\/p>\n

\u5927\u81ea\u7136\u638c\u63e1\u4e86\u5206\u5b50\u8bc6\u522b\u7684\u827a\u672f\u3002\u6211\u4eec\u7684\u79d1\u5b66\u5bb6\u5df2\u7ecf\u5f00\u53d1\u5e76\u7ee7\u7eed\u5f00\u53d1\u6280\u672f\u6765\u7814\u7a76\u548c\u66f4\u597d\u5730\u7406\u89e3\u5206\u5b50\u8bc6\u522b\u3002\u56e0\u6b64\uff0c\u5206\u6790\u7269\u54cd\u5e94\u578b\u6c34\u51dd\u80f6\u5df2\u4f5c\u4e3a\u4e00\u7c7b\u667a\u80fd\u6750\u6599\u6765\u6a21\u62df\u5206\u5b50\u8bc6\u522b\u8fc7\u7a0b\u3002\u4f20\u7edf\u7684\u6c34\u51dd\u80f6\u6839\u636e\u529f\u80fd\u5355\u4f53\u7684\u6027\u8d28\u5bf9\u73af\u5883\u56e0\u5b50\u5982pH\u3001\u6e29\u5ea6\u548c\u79bb\u5b50\u5f3a\u5ea6\u8fdb\u884c\u54cd\u5e94\u3002\u800c\u5206\u6790\u7269\u54cd\u5e94\u578b\u6c34\u51dd\u80f6\u80fd\u6574\u5408\u751f\u7269\u5206\u5b50\u56fa\u6709\u7684\u8bc6\u522b\u6027\u8d28\u3001\u51dd\u80f6\u6eb6\u80c0\u548c\u8131\u6c34\u6536\u7f29\u53cd\u5e94\u7b49\u8fdb\u884c\u54cd\u5e94\uff0c\u5177\u6709\u5e7f\u9614\u7684\u5e94\u7528\u524d\u666f\u3002<\/p>\n

\u6700\u8fd1\uff0c\u7f8e\u56fd\u5fb7\u514b\u8428\u65af\u5927\u5b66\u5965\u65af\u6c40\u5206\u6821\u7684Nicholas A. Peppas\uff08\u901a\u8baf\u4f5c\u8005\uff09<\/strong>\u7b49\u4eba\u7efc\u8ff0\u4e86\u56db\u79cd\u4e0d\u540c\u7c7b\u578b\u7684\u5206\u6790\u7269\u54cd\u5e94\u578b\u7684\u6c34\u51dd\u80f6\u3001\u5e76\u63a2\u8ba8\u8fd9\u4e9b\u6750\u6599\u662f\u5982\u4f55\u6574\u5408\u5230\u751f\u7269\u4f20\u611f\u548c\u836f\u7269\u8f93\u9001\u7cfb\u7edf\u4e2d\u3002\u8fd9\u4e9b\u5185\u5bb9\u4ee5\u201cAnalyte-Responsive Hydrogels: Intelligent Materials for Biosensing and Drug Delivery\u201d<\/strong>\u4e3a\u9898\u4e8e2\u67087\u65e5\u53d1\u8868\u5728\u9876\u7ea7\u7efc\u8ff0\u671f\u520aAccounts of Chemical Research<\/strong>\u4e0a\u3002<\/p>\n

\"\"\u00a0<\/strong><\/p>\n

\u7efc\u8ff0\u603b\u89c8\u56fe<\/strong><\/p>\n

1.\u7b80\u4ecb<\/strong><\/p>\n

\u523a\u6fc0\u54cd\u5e94\u578b\u7684\u6c34\u51dd\u80f6\u5df2\u7ecf\u7814\u7a76\u4e86\u51e0\u5341\u5e74\uff0c\u4e3a\u4e86\u5229\u7528\u4ea4\u8054\u805a\u5408\u7269\u7f51\u7edc\u7684\u73af\u5883\u654f\u611f\u6027\uff0c\u79d1\u5b66\u5bb6\u4eec\u63a7\u5236\u548c\u64cd\u4f5c\u8fd9\u4e9b\u6750\u6599\u7684\u884c\u4e3a\u548c\u5c5e\u6027\u5e76\u8fdb\u884c\u4e86\u5e7f\u6cdb\u5730\u5e94\u7528\u3002\u591a\u529f\u80fd\u7684\u5206\u6790\u7269\u54cd\u5e94\u578b\u6c34\u51dd\u80f6\u6839\u636e\u5206\u5b50\u7684\u8bc6\u522b\u539f\u7406\uff0c\u5e76\u5728\u5206\u6790\u7269\u7684\u591a\u6837\u6027\u3001\u54cd\u5e94\u884c\u4e3a\u548c\u751f\u7269\u533b\u5b66\u5e94\u7528\u7b49\u65b9\u9762\u8bc1\u660e\u6709\u5f88\u591a\u65b9\u5f0f\u5b9e\u73b0\u5206\u5b50\u8bc6\u522b\u3002\u4f20\u7edf\u805a\u5408\u7269\u7cfb\u7edf\u4e2d\u5206\u5b50\u8bc6\u522b\u662f\u901a\u8fc7\u6574\u5408\u529f\u80fd\u5355\u4f53\u6765\u6709\u5229\u4e8e\u5206\u6790\u7269\u8fdb\u884c\u4ea4\u4e92\u3002\u4e3a\u4e86\u66f4\u597d\u5730\u63a7\u5236\u6574\u5408\u5b98\u80fd\u57fa\u56e2\u5e76\u63d0\u9ad8\u4eb2\u548c\u529b\uff0c\u53ef\u4ee5\u91c7\u7528\u5206\u5b50\u5370\u8ff9\u7b56\u7565\u3002\u53e6\u5916\uff0c\u751f\u7269\u5206\u5b50\u548c\u67d0\u4e00\u5206\u6790\u7269\u5177\u6709\u826f\u597d\u7684\u4eb2\u548c\u529b\uff0c\u53ef\u4ee5\u901a\u8fc7\u5171\u8f6d\u805a\u5408\u7269\u5b9e\u73b0\u8bc6\u522b\u548c\u4f20\u9012\u54cd\u5e94\u4fe1\u53f7\u3002<\/p>\n

\u8fd9\u4e9b\u7cfb\u7edf\u53ef\u4ee5\u8bbe\u8ba1\u7528\u6765\u54cd\u5e94\u4ece\u91cd\u91d1\u5c5e\u79bb\u5b50\u5230\u5927\u5206\u5b50\u548c\u7ec6\u80de\u7684\u5404\u79cd\u5206\u6790\u7269\u3002\u6b64\u5916\uff0c\u6c34\u51dd\u80f6\u6709\u591a\u79cd\u65b9\u5f0f\u5bf9\u5206\u6790\u7269\u8fdb\u884c\u54cd\u5e94\uff0c\u56e0\u54cd\u5e94\u884c\u4e3a\u53ea\u7ed1\u5b9a\u76ee\u6807\u5206\u6790\u7269\uff0c\u5927\u90e8\u5206\u5206\u5b50\u8bc6\u522b\u4e8b\u4ef6\u4f34\u968f\u7740\u6784\u8c61\u7684\u53d8\u5316\u3002\u4f8b\u5982\uff0c\u4e0e\u6a21\u677f\u53d1\u751f\u4ea4\u4e92\u5bfc\u81f4\u6c34\u51dd\u80f6\u5185\u7684pH\u3001\u51c0\u7535\u8377\u7b49\u5fae\u73af\u5883\u7684\u53d8\u5316\u5f15\u8d77\u6eb6\u80c0\u6216\u6d88\u6eb6\u80c0\u7b49\u3002<\/p>\n

\u5206\u6790\u7269\u54cd\u5e94\u578b\u6c34\u51dd\u80f6\u8fd9\u4e00\u7c7b\u667a\u80fd\u6750\u6599\u5177\u6709\u5e7f\u6cdb\u7684\u5e94\u7528\uff0c\u5982\u751f\u7269\u4f20\u611f\u548c\u836f\u7269\u8f93\u9001\u7cfb\u7edf\u3002<\/p>\n

\"\"
\n\u56fe1 \u6c34\u51dd\u80f6\u5728\u751f\u7269\u4f20\u611f\u548c\u836f\u7269\u8f93\u9001\u7cfb\u7edf\u7684\u5e94\u7528<\/strong><\/p>\n

2.\u5206\u6790\u7269\u654f\u611f\u578b\u6750\u6599\u7684\u79cd\u7c7b<\/strong><\/p>\n

2.1 \u975e\u5370\u8ff9\u578b\u8bc6\u522b\u7684\u6c34\u51dd\u80f6<\/strong><\/p>\n

\u4e00\u4e2a\u975e\u5e38\u57fa\u672c\u7684\u8bc6\u522b\u5f62\u5f0f\u662f\u4f53\u79ef\u6392\u963b\uff0c\u901a\u8fc7\u6e10\u8fdb\u5f0f\u52a0\u5165\u5206\u5b50\u969c\u788d\u7269\u5982\u4ea4\u8054\u3001\u8fde\u7ed3\u70b9\u548c\u5fae\u6676\u6765\u5b9e\u73b0\u3002\u8fd9\u4e9b\u969c\u788d\u5141\u8bb8\u5206\u5b50\u4f4e\u4e8e\u7279\u5b9a\u5206\u5b50\u91cf\u7684\u7269\u8d28\u5728\u7f51\u7edc\u7a7a\u9699\u4e2d\u6269\u6563\uff0c\u800c\u66f4\u5927\u7684\u7269\u8d28\u5219\u6392\u9664\u5728\u5916\u3002\u6b64\u5916\uff0c\u5355\u4f53\u4e0e\u76ee\u6807\u5206\u6790\u7269\u5f62\u6210\u826f\u597d\u7684\u975e\u5171\u4ef7\u4f5c\u7528\u53ef\u4ee5\u878d\u5165\u5230\u6c34\u51dd\u80f6\u4e2d\u3002\u4e3a\u4e86\u83b7\u5f97\u66f4\u9ad8\u4eb2\u548c\u529b\u548c\u7279\u5f02\u6027\uff0c\u591a\u529f\u80fd\u5206\u5b50\u5728\u6c34\u51dd\u80f6\u805a\u5408\u8fc7\u7a0b\u4e2d\u6216\u5408\u6210\u540e\u4fee\u9970\u8fdb\u884c\u6574\u5408\u3002<\/p>\n

2.2 \u5206\u5b50\u5370\u8ff9\u5408\u6210\u6c34\u51dd\u80f6<\/strong><\/p>\n

\u5206\u5b50\u5370\u8ff9\u805a\u5408\u7269\uff08MIPS\uff09\u6700\u521d\u5e94\u7528\u4e8e\u8272\u8c31\u9886\u57df\uff0c\u662f\u5bf9\u6a21\u677f\u5206\u5b50\u5177\u6709\u9009\u62e9\u6027\u4eb2\u548c\u529b\u7684\u4ea4\u8054\u7f51\u7edc\u3002\u5206\u5b50\u5370\u8ff9\u805a\u5408\u7269\u5728\u529f\u80fd\u5355\u4f53\u805a\u5408\u4e4b\u524d\u4e0e\u6a21\u677f\u5206\u6790\u7269\u5171\u540c\u5b75\u80b2\uff0c\u805a\u5408\u540e\u9664\u53bb\u5305\u57cb\u5728\u6a21\u677f\u5185\u7684\u6eb6\u5242\u5206\u79bb\u7eaf\u5316MIP\u3002\u901a\u8fc7\u826f\u597d\u7684\u5206\u5b50\u95f4\u7684\u76f8\u4e92\u4f5c\u7528\u548c\u5f62\u72b6\u4e92\u8865\u7684\u534f\u540c\u6548\u5e94\uff0cMIP\u7cfb\u7edf\u5177\u6709\u591a\u79cd\u5206\u6790\u7269\u7684\u9009\u62e9\u6027\u4eb2\u548c\u529b\u3002<\/p>\n

\u4f20\u7edf\u7684\u5206\u5b50\u5370\u8ff9\u5229\u7528\u5c0f\u5206\u5b50\u3001\u86cb\u767d\u8d28\u6216\u7ec6\u80de\u4f5c\u4e3a\u6a21\u677f\uff0c\u4f46\u6297\u539f\u51b3\u5b9a\u57fa\u5370\u8ff9\u65b9\u6cd5\u4f7f\u7528\u4e00\u90e8\u5206\u6216\u591a\u80bd\u800c\u4e0d\u662f\u6574\u4e2a\u5206\u5b50\u3002\u6574\u4e2a\u5206\u5b50\u6216\u6297\u539f\u51b3\u5b9a\u57fa\u53ef\u4ee5\u904d\u5e03\u805a\u5408\u7269\u6eb6\u6db2\u4e2d\uff0c\u5bfc\u81f4\u5927\u91cf\u5370\u8ff9\u6216\u8005\u9650\u5236\u5728\u805a\u5408\u7269\u6eb6\u6db2\u7684\u754c\u9762\u4e0a\uff0c\u5f15\u8d77\u8868\u9762\u5370\u8ff9\u3002<\/p>\n

2.3 \u751f\u7269\u5206\u5b50\u5c01\u88c5\u578b\u6c34\u51dd\u80f6<\/strong><\/p>\n

\u9664\u4e86\u5229\u7528\u7eaf\u7cb9\u7684\u5408\u6210\u65b9\u6cd5\u751f\u6210\u5206\u5b50\u8bc6\u522b\u5143\u7d20\uff0c\u8fd8\u53ef\u4ee5\u901a\u8fc7\u5171\u8f6d\u6216\u5c01\u88c5\u5728\u6c34\u51dd\u80f6\u7f51\u7edc\u4e2d\u3002\u751f\u7269\u5206\u5b50\u4e19\u70ef\u9178\u5316\u4e14\u5305\u542b\u5728\u6574\u4e2a\u805a\u5408\u8fc7\u7a0b\u4e2d\uff0c\u8fd9\u9002\u7528\u4e8e\u751f\u7269\u5206\u5b50\u5728\u53cd\u5e94\u4ecb\u8d28\u4e2d\u53ef\u6eb6\u4e14\u7a33\u5b9a\u7684\u60c5\u51b5\u3002\u53e6\u5916\uff0c\u5408\u6210\u540e\u7684\u4fee\u9970\u53ef\u4ee5\u5728\u6c34\u51dd\u80f6\u4e2d\u4fee\u9970\u8bc6\u522b\u6027\u7684\u751f\u7269\u5206\u5b50\u3002\u8fd9\u4e9b\u7b56\u7565\u5c24\u5176\u9002\u5408\u86cb\u767d\u8d28\uff0c\u56e0\u4e3a\u5176\u7cbe\u5de7\u7684\u4e09\u7ea7\u7ed3\u6784\u53ca\u5728\u5267\u70c8\u7684\u805a\u5408\u6761\u4ef6\u4e0b\u53ef\u4ee5\u53d8\u6027\u7684\u7279\u70b9\u3002<\/p>\n

\u5728\u4e00\u4e9b\u60c5\u51b5\u4e0b\uff0c\u9700\u8981\u751f\u7269\u5206\u5b50\u80fd\u5728\u6c34\u51dd\u80f6\u7684\u5b54\u5185\u81ea\u7531\u79fb\u52a8\u3002\u56e0\u6b64\uff0c\u9700\u8981\u5c06\u751f\u7269\u5206\u5b50\u5728\u6c34\u51dd\u80f6\u7684\u51dd\u80f6\u5316\u524d\u540e\u8fdb\u884c\u5c01\u88c5\u3002<\/p>\n

2.4 \u9176\u54cd\u5e94\u578b\u6c34\u51dd\u80f6<\/strong><\/p>\n

\u9664\u4e86\u901a\u8fc7\u5171\u4ef7\u952e\u6216\u5c01\u88c5\u5c06\u9176\u6574\u5408\u5165\u6c34\u51dd\u80f6\u4e2d\uff0c\u8fd8\u53ef\u4ee5\u5229\u7528\u591a\u80bd-\u5e95\u7269\u8fde\u63a5\u80bd\u4e0e\u6c34\u51dd\u80f6\u76f4\u63a5\u4f5c\u7528\u3002\u8fde\u63a5\u80bd\u53ef\u4ee5\u8026\u5408\u6cbb\u7597\u836f\u7269\u81f3\u805a\u5408\u7269\u8f7d\u4f53\u4e2d\uff0c\u901a\u8fc7\u9176\u964d\u89e3\u8fde\u63a5\u80bd\u91ca\u653e\u836f\u7269\u3002\u53e6\u5916\uff0c\u591a\u80bd\u4ea4\u8054\u5242\u53ef\u4ee5\u5f62\u6210\u805a\u5408\u7269\u7f51\u7edc\uff0c\u9176\u7cfb\u7edf\u6027\u5730\u88c2\u89e3\u8fde\u63a5\u80bd\uff0c\u964d\u4f4e\u6709\u6548\u7684\u4ea4\u8054\uff0c\u589e\u52a0\u805a\u5408\u7269\u81a8\u80c0\u6bd4\u7387\uff0c\u589e\u5f3a\u5206\u5b50\u6e17\u900f\u6027\u3002\u5178\u578b\u7684\u5316\u5b66\u65b9\u6cd5\u5229\u7528\u786b\u9187-\u51b0\u7247\u70ef\u70b9\u51fb\u53cd\u5e94\u8fdb\u884c\u4ea4\u8054\u3002\u8fde\u63a5\u80bd\u5df2\u8bbe\u8ba1\u6210\u5404\u79cd\u53ef\u8c03\u7684\u9176\u964d\u89e3\u4f53\u7cfb\u5982\u57fa\u8d28\u91d1\u5c5e\u86cb\u767d\u9176\u3001\u80f0\u86cb\u767d\u9176\u548c\u5f39\u6027\u86cb\u767d\u9176\u3002<\/p>\n

3.\u5206\u6790\u7269\u54cd\u5e94\u6c34\u51dd\u80f6\u5728\u4f20\u611f\u4e2d\u7684\u5e94\u7528<\/strong><\/p>\n

3.1 \u8bc6\u522b\u5206\u5b50\u5370\u8ff9\u805a\u5408\u7269\u7684\u4f20\u611f\u5e94\u7528<\/strong><\/p>\n

\u5408\u6210\u6c34\u51dd\u80f6\u53ef\u4ee5\u901a\u8fc7\u6574\u5408\u8bf1\u9975\u5206\u5b50\u6216\u5206\u5b50\u5370\u8ff9\u8fdb\u884c\u5206\u5b50\u8bc6\u522b\u3002\u4e00\u65e6\u6c34\u51dd\u80f6\u7ed3\u5408\u5206\u6790\u7269\uff0c\u5c24\u5176\u662f\u5229\u7528\u6eb6\u80c0\u6216\u6d88\u6eb6\u80c0\u8fdb\u884c\u4fe1\u53f7\u8f6c\u5bfc\u65f6\uff0c\u6c34\u51dd\u80f6\u4f1a\u53d1\u751f\u6eb6\u80c0\u6216\u6d88\u6eb6\u80c0\uff0c\u8fd9\u65f6\u4f1a\u6709\u4e24\u4e2a\u660e\u663e\u7684\u53d8\u5316\uff1a\u4f53\u79ef\u53d8\u5316\u548c\u6298\u5c04\u7387\u53d8\u5316\u3002\u6574\u5408\u7684\u6750\u6599\u5bf9\u8fd9\u4e9b\u53d8\u5316\u7075\u654f\uff0c\u901a\u8fc7\u5206\u6790\u7269\u7ed3\u5408\u6765\u5b9e\u73b0\u4fe1\u53f7\u8f6c\u5bfc\u3002<\/p>\n

\"\"<\/p>\n

\u56fe2 \u7518\u9732\u7cd6\u6c34\u51dd\u80f6-\u805a\u82ef\u4e59\u70ef\u7eb3\u7c73\u7c92\u5b50\u7684\u4e8c\u7ef4\u9635\u5217\u626b\u63cf\u7535\u955c\u56fe<\/strong><\/p>\n

3.2 \u751f\u7269\u5206\u5b50\u5c01\u88c5\u578b\u6c34\u51dd\u80f6\u7684\u4f20\u611f\u5e94\u7528<\/strong><\/p>\n

\u8bc6\u522b\u5206\u5b50\u5370\u8ff9\u805a\u5408\u7269\u7279\u522b\u9002\u7528\u4e8e\u4f4e\u6210\u672c\u4f20\u611f\u5e94\u7528\u548c\u5206\u6790\u7269\u6ca1\u6709\u5df2\u77e5\u7ed3\u5408\u914d\u4f53\u7684\u60c5\u51b5\u3002\u751f\u7269\u5206\u5b50\u5c01\u95ed\u578b\u6c34\u51dd\u80f6\u901a\u5e38\u66f4\u6602\u8d35\uff0c\u8fd9\u5229\u7528\u4e86\u751f\u7269\u5206\u5b50\u826f\u597d\u7684\u8bc6\u522b\u6027\u8d28\u3002\u8fd9\u4e9b\u6750\u6599\uff0c\u4e3b\u8981\u7684\u5e94\u7528\u9886\u57df\u662f\u5229\u7528\u4fe1\u53f7\u8f6c\u5bfc\uff0c\u76ee\u7684\u662f\u6539\u5584\u4f20\u611f\u5668\u7684\u68c0\u6d4b\u9650\u3002\u4e00\u4e9b\u8bfe\u9898\u7ec4\u5229\u7528\u5927\u5206\u5b50\u5355\u4f53\u4e19\u70ef\u9178\u916f\u6216\u7532\u57fa\u4e19\u70ef\u9178\u916f\u7684\u6838\u9178\u9002\u914d\u4f53\u7528\u4e8e\u5206\u5b50\u5370\u8ff9\u3002<\/p>\n

\u9664\u4e86\u5229\u7528\u751f\u7269\u5206\u5b50\u56fa\u6709\u7684\u8bc6\u522b\u6027\u8d28\uff0c\u751f\u7269\u5206\u5b50\u4e5f\u53ef\u4ee5\u81ea\u7ec4\u88c5\u8fdb\u884c\u51c6\u786e\u7684\u914d\u4f53\u8bc6\u522b\u3002<\/p>\n

3.3 \u9176\u5305\u542b\u548c\u9176\u54cd\u5e94\u6c34\u51dd\u80f6\u7684\u4f20\u611f\u5e94\u7528<\/strong><\/p>\n

\u9176\u5305\u542b\u548c\u9176\u54cd\u5e94\u6c34\u51dd\u80f6\u662f\u5206\u6790\u7269\u54cd\u5e94\u6750\u6599\u4f20\u611f\u5e94\u7528\u4e2d\u975e\u5e38\u6709\u7528\u7684\u7c7b\u578b\u3002\u8bb8\u591a\u5e38\u89c4\u68c0\u9a8c\u5982\u9176\u8054\u514d\u75ab\u5438\u9644\u68c0\u6d4b\uff0c\u4f9d\u8d56\u9176-\u5e95\u7269\u76f8\u4e92\u4f5c\u7528\u4ea7\u751f\u4e00\u4e2a\u68c0\u6d4b\u4fe1\u53f7\uff0c\u5982\u751f\u6210\u4e00\u4e2a\u6709\u989c\u8272\u7684\u4ea7\u7269\u3002\u5206\u6790\u7269\u54cd\u5e94\u578b\u6c34\u51dd\u80f6\u7684\u53cd\u5e94\u9176\u6216\u9632\u62a4\u9176\u4e00\u65e6\u52a0\u5165\u5206\u6790\u7269\u53ef\u80fd\u4f1a\u4ea7\u751f\u6784\u8c61\u7684\u53d8\u5316\u800c\u5b9e\u73b0\u4fe1\u53f7\u7684\u68c0\u6d4b\u3002\u6b64\u5916\uff0c\u9176\u5904\u4e8e\u5c0f\u4f53\u79ef\u7684\u6c34\u51dd\u80f6\u4e2d\uff0c\u9176\u7684\u5c40\u90e8\u6d53\u5ea6\u9ad8\uff0c\u53cd\u800c\u53ef\u4ee5\u5b9e\u73b0\u7075\u654f\u68c0\u6d4b\u3002<\/p>\n

\"\"<\/p>\n

\u56fe3 \u8461\u7cd6\u6dc0\u7c89\u9176\u68c0\u6d4b\u7684\u793a\u610f\u56fe<\/strong><\/p>\n

4.\u5206\u6790\u7269\u7684\u6355\u83b7\u548c\u91ca\u653e\u7528\u4e8e\u836f\u7269\u6cbb\u7597<\/strong><\/p>\n

\u5206\u6790\u7269\u54cd\u5e94\u7684\u805a\u5408\u7269\u5df2\u5728\u5404\u79cd\u53ef\u63a7\u6216\u9776\u5411\u836f\u7269\u8fd0\u8f7d\u7cfb\u7edf\u4e2d\u91c7\u7528\u3002\u8fd9\u4e9b\u667a\u80fd\u6750\u6599\u53ef\u4ee5\u901a\u8fc7\u7f51\u7edc\u964d\u89e3\u7b49\u4e3a\u7279\u5f81\u3002\u6700\u8fd1\u5206\u6790\u7269\u54cd\u5e94\u578b\u6750\u6599\u5728\u5c0f\u5206\u5b50\u548c\u86cb\u767d\u836f\u7269\u8fd0\u8f7d\u4e2d\u8fdb\u884c\u4e86\u5e7f\u6cdb\u5e94\u7528\u3002<\/p>\n

\"\"
\n\u56fe4 \u54cd\u5e94\u578b\u6c34\u51dd\u80f6\u836f\u7269\u8fd0\u8f7d\u7cfb\u7edf\u7684\u673a\u7406\u56fe<\/strong><\/p>\n

4.1 \u8bc6\u522b\u5206\u5b50\u5370\u8ff9\u805a\u5408\u7269\u7684\u836f\u7269\u8f93\u9001<\/strong><\/p>\n

\u6c34\u51dd\u80f6\u672c\u8eab\u5728\u7f3a\u4e4f\u5148\u8fdb\u7684\u6784\u9020\u65f6\u5177\u6709\u5206\u5b50\u76f8\u4e92\u4f5c\u7528\u548c\u8bc6\u522b\u7684\u80fd\u529b\u3002\u5408\u6210\u7684\u805a\u5408\u7269\u4e0e\u751f\u7269\u6807\u8bb0\u7269\u6216\u8005\u836f\u7269\u5177\u6709\u826f\u597d\u7684\u9759\u7535\u76f8\u4e92\u4f5c\u7528\u3001\u758f\u6c34\u4f5c\u7528\u548c\u6c22\u952e\u4f5c\u7528\u3002<\/p>\n

\u5206\u5b50\u5370\u8ff9\u5229\u7528\u5927\u91cf\u7814\u7a76\u63d0\u9ad8\u667a\u80fd\u7f51\u7edc\u5bf9\u7279\u5b9a\u6cbb\u7597\u5242\u7684\u4eb2\u548c\u529b\u3002\u968f\u7740\u805a\u5408\u7269-\u836f\u7269\u7684\u4eb2\u548c\u529b\u589e\u5f3a\uff0c\u836f\u7269\u91ca\u653e\u6301\u7eed\u65f6\u95f4\u66f4\u957f\u3002\u4e00\u4e9b\u539f\u521b\u6027\u7684\u5de5\u4f5c\u901a\u8fc7\u5206\u5b50\u5370\u8ff9\u5ef6\u957f\u773c\u90e8\u7ed9\u836f\u7684\u6301\u7eed\u65f6\u95f4\u3002\u4e0e\u5229\u7528\u6cbb\u7597\u836f\u7269\u4f5c\u4e3a\u5370\u8ff9\u6a21\u677f\u76f8\u6bd4\uff0c\u79d1\u7814\u4eba\u5458\u53ef\u4ee5\u5370\u4e0a\u751f\u7269\u6807\u8bb0\u7269\u4fc3\u8fdb\u9776\u5411\u836f\u7269\u7684\u91ca\u653e\u3002\u5229\u7528\u86cb\u767d\u8d28\u6216\u6297\u539f\u51b3\u5b9a\u57fa\u7684\u8868\u9762\u5370\u8ff9\u83b7\u5f97\u5728\u805a\u5408\u7269\u5185\u6750\u6599\u9776\u5411\u5c01\u88c5\u6216\u5438\u5165\u5c0f\u5206\u5b50\u836f\u7269\u3002<\/p>\n

\"\"
\n\u56fe5 \u6297\u539f\u51b3\u5b9a\u57fa\u5370\u8ff9\u805a\u5408\u7269\u7eb3\u7c73\u7c92\u5b50\u7279\u5f02\u6027\u8bc6\u522bp32\u53d7\u4f53\uff0c\u5e76\u8fd0\u8f7d\u5c0f\u5206\u5b50\u5149\u654f\u5242\u7684\u793a\u610f\u56fe<\/strong><\/p>\n

4.2 \u751f\u7269\u5206\u5b50\u5c01\u88c5\u578b\u6c34\u51dd\u80f6\u7684\u836f\u7269\u8f93\u9001<\/strong><\/p>\n

\u589e\u5f3a\u805a\u5408\u7269-\u836f\u7269\u7684\u4eb2\u548c\u529b\u7528\u4e8e\u836f\u7269\u91ca\u653e\u7684\u53e6\u4e00\u4e2a\u7b56\u7565\u662f\u4fee\u9970\u5176\u4ed6\u7684\u975e\u7279\u5f02\u6027\u7684\u76ee\u6807\u914d\u4f53\u805a\u5408\u7269\u3002\u6b64\u5916\uff0c\u751f\u7269\u5206\u5b50\u5229\u7528\u7269\u7406\u4ea4\u8054\u7684\u65b9\u6cd5\u5305\u542b\u5728\u6c34\u51dd\u80f6\u7f51\u7edc\u4e2d\u3002<\/p>\n

4.3 \u9176\u5305\u542b\u6216\u9176\u54cd\u5e94\u6c34\u51dd\u80f6\u7684\u836f\u7269\u8f93\u9001<\/strong><\/p>\n

\u7814\u7a76\u4eba\u5458\u53ef\u4ee5\u5171\u8f6d\u751f\u7269\u6d3b\u6027\u7684\u9176\u81f3\u5408\u6210\u6216\u5929\u7136\u6c34\u51dd\u80f6\u7f51\u7edc\uff0c\u5728\u751f\u7269\u4f53\u5185\u76f4\u63a5\u4e0e\u751f\u7269\u6807\u8bb0\u7269\u4f5c\u7528\u5e76\u901a\u8fc7\u805a\u5408\u7269\u7f51\u7edc\u7684\u7269\u7406\u53d8\u5316\u89e6\u53d1\u836f\u7269\u7684\u91ca\u653e\u3002\u53e6\u5916\uff0c\u5728\u6b63\u5e38\u7684\u751f\u7406\u73af\u5883\u4e0b\u9176\u53ef\u4ee5\u4e0e\u54cd\u5e94\u578b\u6c34\u51dd\u80f6\u76f8\u4e92\u4f5c\u7528\u53ca\u4fee\u9970\u3002<\/p>\n

\"\"
\n\u56fe6 \u7cd6\u5c3f\u75c5\u5c0f\u9f20\u6ce8\u5c04\u8d1f\u8f7d\u80f0\u5c9b\u7d20\u7684\u8461\u8404\u7cd6\u54cd\u5e94\u7eb3\u7c73\u7f51\u7edc\u540e\u7ef4\u6301\u8840\u7cd6\u6b63\u5e38\u6c34\u5e73\u7684\u65f6\u95f4\u54cd\u5e94\u56fe<\/strong><\/p>\n

4.4 \u805a\u5408\u7269\u4fee\u9970\u5206\u5b50\u8bc6\u522b\u7684\u9776\u5411\u836f\u7269\u8f93\u9001<\/strong><\/p>\n

\u7ed3\u5408\u9776\u5411\u914d\u4f53\u5982\u6297\u4f53\u3001\u6838\u9178\u9002\u914d\u4f53\u6216\u591a\u80bd\u662f\u5b9e\u73b0\u9776\u5411\u836f\u7269\u8f93\u9001\u7684\u4e00\u79cd\u666e\u904d\u7684\u65b9\u6cd5\u3002\u914d\u4f53\u7ed3\u5408\u836f\u7269\u8fd0\u8f7d\u4f53\u540e\u9776\u5411\u75c5\u53d8\u7ec4\u7ec7\u662f\u4e00\u4e2a\u5e7f\u6cdb\u7684\u7814\u7a76\u9886\u57df\u4e14\u662f\u5927\u91cf\u7efc\u8ff0\u4e2d\u7684\u552f\u4e00\u8bdd\u9898\u3002\u867d\u7136\u672c\u7efc\u8ff0\u4e3b\u8981\u662f\u7a81\u51fa\u5206\u6790\u7269\u54cd\u5e94\u6027\u6750\u6599\u9886\u57df\u7684\u8fdb\u5c55\uff0c\u4f46\u662f\u5982\u679c\u4e0d\u7a81\u51fa\u5206\u6790\u7269\u54cd\u5e94\u6750\u6599\u548c\u76ee\u6807\u914d\u4f53\u7ed3\u5408\u7b56\u7565\u7684\u8fdb\u5c55\u5c31\u662f\u6211\u4eec\u4f5c\u8005\u7684\u758f\u5ffd\u3002<\/p>\n

\u3010\u603b\u7ed3\u3011<\/strong><\/p>\n

\u4f5c\u8005\u603b\u7ed3\u4e86\u5206\u6790\u7269\u54cd\u5e94\u578b\u6c34\u51dd\u80f6\u7684\u4e0d\u540c\u7c7b\u578b\uff0c\u5e76\u7efc\u8ff0\u4e86\u8fd9\u4e9b\u6750\u6599\u5728\u751f\u7269\u4f20\u611f\u548c\u836f\u7269\u8f93\u9001\u9886\u57df\u7684\u5e94\u7528\u3002\u5728\u4f20\u611f\u9886\u57df\uff0c\u9ad8\u7075\u654f\u5ea6\u548c\u9009\u62e9\u6027\u53ca\u4f4e\u751f\u4ea7\u6210\u672c\u7684\u6f5c\u529b\u4f7f\u5206\u6790\u7269\u54cd\u5e94\u578b\u6c34\u51dd\u80f6\u5728\u4ef7\u503c\u5bfc\u5411\u7684\u533b\u7597\u65f6\u4ee3\u6210\u4e3a\u91cd\u8981\u7684\u8bca\u65ad\u5de5\u5177\u3002\u6b64\u5916\uff0c\u53ef\u63a7\u7684\u6216\u9776\u5411\u7684\u836f\u7269\u91ca\u653e\u4f7f\u6c34\u51dd\u80f6\u6210\u4e3a\u65b0\u836f\u7269\u7ba1\u7406\u7b56\u7565\u548c\u964d\u4f4e\u975e\u76ee\u6807\u526f\u4f5c\u7528\u7684\u6709\u5438\u5f15\u529b\u7684\u5e73\u53f0\u3002\u6211\u4eec\u671f\u5f85\u521b\u9020\u6027\u548c\u7ec4\u5408\u7684\u65b9\u6cd5\u5e94\u7528\u4e8e\u6c34\u51dd\u80f6\u7684\u8bbe\u8ba1\u5e76\u7ee7\u7eed\u5f00\u53d1\u51fa\u5728\u4f20\u611f\u548c\u836f\u7269\u8f93\u9001\u7cfb\u7edf\u4e2d\u4ea7\u751f\u5de8\u5927\u6f5c\u529b\u7684\u6750\u6599\u3002<\/p>\n

\u6587\u732e\u94fe\u63a5\uff1a<\/strong> Analyte-Responsive Hydrogels: Intelligent Materials for Biosensing and Drug Delivery<\/a>\u00a0(Acc. Chem. Res.,2017,DOI: 10.1021\/acs.accounts.6b00533)<\/p>\n

\u672c\u6587\u7531\u6750\u6599\u4eba\u751f\u7269\u6750\u6599\u7ec4\u9093\u5b8f\u534e\u4f9b\u7a3f\uff0c\u6750\u6599\u725b\u7f16\u8f91\u6574\u7406\u3002<\/p>\n

\u6750\u6599\u725b\u7f51\u4e13\u6ce8\u4e8e\u8ddf\u8e2a\u6750\u6599\u9886\u57df\u79d1\u6280\u53ca\u884c\u4e1a\u8fdb\u5c55\uff0c\u8fd9\u91cc\u6c47\u96c6\u4e86\u5404\u5927\u9ad8\u6821\u7855\u535a\u751f\u3001\u4e00\u7ebf\u79d1\u7814\u4eba\u5458\u4ee5\u53ca\u884c\u4e1a\u4ece\u4e1a\u8005\uff0c\u5982\u679c\u60a8\u5bf9\u4e8e\u8ddf\u8e2a\u6750\u6599\u9886\u57df\u79d1\u6280\u8fdb\u5c55\uff0c\u89e3\u8bfb\u9ad8\u6c34\u5e73\u6587\u7ae0\u6216\u662f\u8bc4\u8ff0\u884c\u4e1a\u6709\u5174\u8da3\uff0c\u70b9\u6211\u52a0\u5165\u7f16\u8f91\u90e8<\/a>\u3002<\/p>\n

\u6750\u6599\u6d4b\u8bd5\uff0c\u6570\u636e\u5206\u6790\uff0c\u4e0a\u6d4b\u8bd5\u8c37<\/a>\uff01<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"

\u3010\u5f15\u8a00\u3011 \u5927\u81ea\u7136\u638c\u63e1\u4e86\u5206\u5b50\u8bc6\u522b\u7684\u827a\u672f\u3002\u6211\u4eec\u7684\u79d1\u5b66\u5bb6\u5df2\u7ecf\u5f00\u53d1\u5e76\u7ee7\u7eed\u5f00\u53d1\u6280\u672f\u6765\u7814\u7a76\u548c\u66f4\u597d\u5730\u7406\u89e3\u5206\u5b50\u8bc6\u522b\u3002\u56e0\u6b64\uff0c\u5206\u6790\u7269\u54cd\u5e94\u578b\u6c34\u51dd\u80f6\u5df2\u4f5c\u4e3a\u4e00\u7c7b\u667a\u80fd\u6750\u6599\u6765\u6a21\u62df\u5206\u5b50\u8bc6\u522b\u8fc7\u7a0b…<\/p>\n","protected":false},"author":1745,"featured_media":65706,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[533],"tags":[1411,20,75],"class_list":["post-65689","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-zongshu","tag-nicholas-a-peppas","tag-zhineng","tag-biomaterial"],"_links":{"self":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts\/65689"}],"collection":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/users\/1745"}],"replies":[{"embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=65689"}],"version-history":[{"count":11,"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts\/65689\/revisions"}],"predecessor-version":[{"id":65974,"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts\/65689\/revisions\/65974"}],"wp:featuredmedia":[{"embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/media\/65706"}],"wp:attachment":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=65689"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=65689"},{"taxonomy":"post_tag","embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=65689"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}