{"id":62173,"date":"2017-01-22T06:30:16","date_gmt":"2017-01-21T22:30:16","guid":{"rendered":"\/\/m.iemloyee.com\/?p=62173"},"modified":"2017-01-20T16:51:16","modified_gmt":"2017-01-20T08:51:16","slug":"acc-chem-res-%e8%92%8b%e5%85%b4%e5%ae%87%e6%9c%80%e6%96%b0%e7%bb%bc%e8%bf%b0%ef%bc%9a%e5%b0%8f%e5%88%86%e5%ad%90%e8%a1%a8%e9%9d%a2%e4%bf%ae%e9%a5%b0%e9%87%91%e7%ba%b3%e7%b1%b3%e9%a2%97%e7%b2%92","status":"publish","type":"post","link":"\/\/m.iemloyee.com\/?p=62173","title":{"rendered":"Acc. Chem. Res. \u848b\u5174\u5b87\u6700\u65b0\u7efc\u8ff0\uff1a\u5c0f\u5206\u5b50\u8868\u9762\u4fee\u9970\u91d1\u7eb3\u7c73\u9897\u7c92\u7528\u4e8e\u751f\u5316\u5206\u6790"},"content":{"rendered":"<p><strong>\u3010\u5f15\u8bed\u3011<\/strong><\/p>\n<p>\u751f\u5316\u5206\u6790\uff08biochemical analysis\uff09\u5982\u4eca\u5728\u4e34\u5e8a\u8bca\u65ad\u3001\u98df\u54c1\u5b89\u5168\u4ee5\u53ca\u73af\u5883\u76d1\u6d4b\u7b49\u9886\u57df\u53d1\u6325\u7740\u8d8a\u6765\u8d8a\u91cd\u8981\u7684\u4f5c\u7528\u3002\u800c\u57fa\u4e8e\u7eb3\u7c73\u9897\u7c92\u7684\u751f\u5316\u5206\u6790\u6280\u672f\u968f\u7740\u7eb3\u7c73\u6280\u672f\u7684\u4e0d\u65ad\u53d1\u5c55\u4e5f\u5728\u4e0d\u65ad\u5730\u8fdb\u6b65\u3002\u529f\u80fd\u5316\u7684\u7eb3\u7c73\u9897\u7c92\u56e0\u5176\u72ec\u7279\u7684\u7269\u7406\u548c\u5316\u5b66\u6027\u8d28\u53ef\u4ee5\u52a0\u901f\u4fe1\u53f7\u8f6c\u5bfc\u3001\u589e\u5927\u4fe1\u53f7\u5f3a\u5ea6\u4ee5\u53ca\u5b9e\u73b0\u4fe1\u53f7\u7684\u4fbf\u6377\u8bfb\u53d6\uff0c\u4ece\u800c\u5927\u5e45\u63d0\u9ad8\u751f\u5316\u5206\u6790\u6027\u80fd\u3002\u8fd1\u671f\uff0c\u56fd\u5bb6\u7eb3\u7c73\u79d1\u5b66\u4e2d\u5fc3\u7684\u848b\u5174\u5b87\u8bfe\u9898\u7ec4\u5728\u9876\u7ea7\u7efc\u8ff0\u671f\u520a<strong><em>Acc. Chem. Res. <\/em><\/strong>\u4e0a\u53d1\u8868\u9898\u4e3a\u201cSurface Modification of Gold Nanoparticles with Small Molecules for Biochemical Analysis\u201d\u7684\u7efc\u8ff0\u3002\u8be5\u7bc7\u7efc\u8ff0\u7684\u4e3b\u9898\u662f<strong>\u603b\u7ed3\u73b0\u9636\u6bb5\u91d1\u7eb3\u7c73\u9897\u7c92\u7684\u4fee\u9970\u7b56\u7565\u5e76\u9610\u91ca\u5982\u4f55\u5229\u7528\u8fd9\u4e9b\u8868\u9762\u4fee\u9970\u7b56\u7565\u6765\u63d0\u9ad8\u91d1\u7eb3\u7c73\u9897\u7c92\u4ecb\u5bfc\u5206\u6790\u65b9\u6cd5\u7684\u6027\u80fd\u3002<\/strong><strong style=\"line-height: 1.5;\">\u00a0 \u00a0\u00a0<\/strong><\/p>\n<p><strong><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-62179\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2017\/01\/\u7efc\u8ff0\u5bfc\u89c8.jpg\" alt=\"\" width=\"700\" height=\"352\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2017\/01\/\u7efc\u8ff0\u5bfc\u89c8.jpg 700w, \/\/m.iemloyee.com\/wp-content\/uploads\/2017\/01\/\u7efc\u8ff0\u5bfc\u89c8-300x151.jpg 300w\" sizes=\"(max-width: 700px) 100vw, 700px\" \/><\/strong><\/p>\n<p style=\"text-align: center;\">\u7efc\u8ff0\u5bfc\u89c8\u56fe<\/p>\n<p><strong>1.\u7b80\u4ecb<\/strong><\/p>\n<p>\u51ed\u7740\u5de8\u5927\u7684\u6bd4\u8868\u9762\u79ef\u548c\u4f18\u5f02\u7684\u5149\u3001\u78c1\u4ee5\u53ca\u7535\u5b66\u6027\u80fd\uff0c\u529f\u80fd\u5316\u7684\u7eb3\u7c73\u9897\u7c92\u53ef\u4ee5\u4f5c\u4e3a\u6837\u54c1\u9884\u5904\u7406\u7684\u8f7d\u4f53\u3001\u4fe1\u53f7\u8bc6\u522b\u5143\u7d20\u6216\u8005\u4fe1\u53f7\u8bfb\u51fa\u63a2\u9488\u800c\u5728\u4f20\u611f\u9886\u57df\u5b58\u5728\u7740\u5e7f\u6cdb\u7684\u5e94\u7528\u3002\u800c\u8868\u9762\u5316\u5b66\u662f\u7eb3\u7c73\u9897\u7c92\u529f\u80fd\u5316\u6700\u4e3b\u8981\u7684\u5de5\u5177\uff0c\u7279\u522b\u662f\u5728\u751f\u5316\u5206\u6790\u9886\u57df\uff0c\u8868\u9762\u4fee\u9970\u7684\u7b56\u7565\u5bf9\u7eb3\u7c73\u9897\u7c92\u4ecb\u5bfc\u7684\u5206\u6790\u8fc7\u7a0b\u662f\u81f3\u5173\u91cd\u8981\u7684\u3002<\/p>\n<p>\u4f17\u6240\u5468\u77e5\uff0c\u91d1\u7eb3\u7c73\u9897\u7c92\u62e5\u6709\u4e0e\u5c3a\u5bf8\u3001\u5f62\u8c8c\u7b49\u76f8\u5173\u7684\u5149\u5b66\u6027\u8d28\u3002\u6bd4\u5982\u6eb6\u6db2\u4e2d\u76ee\u6807\u8bf1\u5bfc\u7684\u96c6\u805a\u80fd\u591f\u4fc3\u4f7f\u7c92\u5b50\u95f4\u7b49\u79bb\u6fc0\u5143\u8026\u5408\uff08plasmon coupling\uff09\u53d1\u751f\uff0c\u4ece\u800c\u5bfc\u81f4\u53ef\u89c1\u5149\u533a\u57df\u7684\u5438\u6536\u5e26\u79fb\u52a8\uff0c\u8868\u73b0\u5728\u5b8f\u89c2\u4e0a\u4fbf\u662f\u4f9d\u8d56\u4e8e\u76ee\u6807\u7269\u6d53\u5ea6\u7684\u6eb6\u6db2\u989c\u8272\u53d8\u5316\u3002\u56e0\u6b64\uff0c\u91d1\u7eb3\u7c73\u9897\u7c92\u6eb6\u6db2\u662f\u7528\u4e8e\u8bbe\u8ba1\u53ef\u89c1\u4f20\u611f\u5668\u7684\u7edd\u4f73\u5e73\u53f0\u3002\u73b0\u6709\u7684\u7efc\u8ff0\u5927\u591a\u5173\u6ce8\u5229\u7528\u805a\u5408\u7269\u548c\u751f\u7269\u5927\u5206\u5b50\u4f5c\u4e3a\u91d1\u7eb3\u7c73\u9897\u7c92\u8868\u9762\u4fee\u9970\u7269\uff0c\u800c\u4e0e\u5c0f\u5206\u5b50\u4fee\u9970\u91d1\u7eb3\u7c73\u9897\u7c92\u76f8\u5173\u7684\u7efc\u8ff0\u5374\u5c11\u6709\u51fa\u73b0\u3002\u5305\u62ec\u6c28\u57fa\u9178\u4ee5\u53ca\u5def\u57fa\u5316\u5408\u7269\u5728\u5185\u7684\u5c0f\u5206\u5b50\u7269\u8d28\u76f8\u6bd4\u8d77\u6297\u4f53\u3001\u9176\u3001\u591a\u7cd6\u7b49\u751f\u7269\u5927\u5206\u5b50\u5177\u6709\u66f4\u7b80\u5355\u7684\u7ed3\u6784\u4ee5\u53ca\u66f4\u5c0f\u7684\u4f4d\u963b\u6548\u5e94\uff0c\u66f4\u52a0\u5bb9\u6613\u548c\u53ef\u63a7\u5730\u5728\u91d1\u7eb3\u7c73\u9897\u7c92\u8868\u9762\u8fdb\u884c\u751f\u7269\u5076\u8054\u3002\u6b64\u5916\uff0c\u5c0f\u5206\u5b50\u7684\u5b9a\u5411\u548c\u53ef\u4eb2\u6027\uff08accessibility\uff09\u53ef\u4ee5\u5728\u4e0d\u964d\u4f4e\u751f\u7269\u6d3b\u6027\u7684\u524d\u63d0\u4e0b\u88ab\u51c6\u786e\u5730\u63a7\u5236\uff0c\u56e0\u6b64\u5c0f\u5206\u5b50\u529f\u80fd\u5316\u7684\u91d1\u7eb3\u7c73\u9897\u7c92\u5728\u751f\u5316\u5206\u6790\u8fc7\u7a0b\u4e2d\u53ef\u4ee5\u53d8\u5f97\u66f4\u52a0\u7a33\u5b9a\u548c\u53ef\u91cd\u590d\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-62174\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2017\/01\/\u56fe1-1.jpeg\" alt=\"\" width=\"700\" height=\"697\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2017\/01\/\u56fe1-1.jpeg 700w, \/\/m.iemloyee.com\/wp-content\/uploads\/2017\/01\/\u56fe1-1-150x150.jpeg 150w, \/\/m.iemloyee.com\/wp-content\/uploads\/2017\/01\/\u56fe1-1-300x300.jpeg 300w\" sizes=\"(max-width: 700px) 100vw, 700px\" \/><\/p>\n<p style=\"text-align: center;\"><strong>\u56fe<\/strong><strong>1 <\/strong>\u5229\u7528\u5c0f\u5206\u5b50\u529f\u80fd\u5316\u91d1\u7eb3\u7c73\u9897\u7c92\u7684\u8868\u9762\u5316\u5b66<\/p>\n<p><strong>2.\u91d1\u7eb3\u7c73\u9897\u7c92\u7684\u8868\u9762\u5316\u5b66<\/strong><\/p>\n<p><strong>2.1 <\/strong><strong>\u57fa\u4e8e\u70b9\u51fb\u5316\u5b66\u7684\u8868\u9762\u7ed3\u5408\uff08<\/strong><strong>conjugation<\/strong><strong>\uff09\u6280\u672f<\/strong><\/p>\n<p>\u70b9\u51fb\u5316\u5b66\uff08click chemistry\uff09\u5e7f\u6cdb\u7528\u4e8e\u6750\u6599\u79d1\u5b66\u548c\u751f\u7269\u5b66\u7684\u7ed3\u5408\u5e94\u7528\uff0c\u6bd4\u5982\u805a\u5408\u7269\u7684\u5408\u6210\u3001\u751f\u7269\u5076\u8054\uff08bioconjugation\uff09\u4ee5\u53ca\u751f\u7269\u6210\u50cf\u6280\u672f\u3002\u56e0\u4e3a\u4e0d\u4f1a\u5f71\u54cd\u7eb3\u7c73\u9897\u7c92\u7684\u7ed3\u6784\uff0c\u70b9\u51fb\u5316\u5b66\u4e00\u76f4\u90fd\u662f\u975e\u5e38\u91cd\u8981\u7684\u8868\u9762\u4fee\u9970\u7b56\u7565\u3002\u5728\u4f17\u591a\u7684\u70b9\u51fb\u53cd\u5e94\u7c7b\u578b\u4e2d\uff0cCu(I)\u50ac\u5316\u7684\u7094\u70c3\u548c\u53e0\u6c2e\u5316\u7269\uff08CuAAC\uff09\u5076\u6781\u73af\u52a0\u6210\u53cd\u5e94\uff08dipolar cycloaddition\uff09\u662f\u5e94\u7528\u6700\u4e3a\u5e7f\u6cdb\u7684\u3002\u5728Cu(I)\u7684\u50ac\u5316\u4e0b\uff0c\u7094\u70c3\u548c\u53e0\u6c2e\u5316\u7269\u7684\u53cd\u5e94\u53ef\u4ee5\u5728\u6e29\u548c\u7684\u6761\u4ef6\u4e0b\u5feb\u901f\u8fdb\u884c\uff0c\u4ece\u800c\u53ef\u4ee5\u7528\u6765\u53d1\u5c55\u4e00\u7cfb\u5217\u53ef\u4ee5\u88f8\u773c\u8bfb\u6570\u7684\u751f\u5316\u5206\u6790\u8fc7\u7a0b\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-62175\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2017\/01\/\u56fe2-1.jpeg\" alt=\"\" width=\"700\" height=\"519\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2017\/01\/\u56fe2-1.jpeg 700w, \/\/m.iemloyee.com\/wp-content\/uploads\/2017\/01\/\u56fe2-1-300x222.jpeg 300w\" sizes=\"(max-width: 700px) 100vw, 700px\" \/><\/p>\n<p style=\"text-align: center;\"><strong>\u56fe<\/strong><strong>2<\/strong> CuAAC\u4ecb\u5bfc\u7684\u91d1\u7eb3\u7c73\u9897\u7c92\u8868\u9762\u5316\u5b66\u7528\u4e8e\u53ef\u89c6\u5316\u68c0\u6d4b<\/p>\n<p><strong>2.2 <\/strong><strong>\u57fa\u4e8e\u914d\u4f4d\u8bc6\u522b\uff08<\/strong><strong>coordination-based recognition<\/strong><strong>\uff09\u7684\u8868\u9762\u4fee\u9970<\/strong><\/p>\n<p><strong>2.2.1 <\/strong><strong>\u6c28\u57fa\u9178\u4ecb\u5bfc\u7684\u8868\u9762\u4fee\u9970<\/strong><\/p>\n<p>\u901a\u8fc7Au-S\u952e\uff0c\u8bb8\u591a\u7c7b\u578b\u7684\u6c28\u57fa\u9178\u90fd\u53ef\u4ee5\u4fee\u9970\u91d1\u7eb3\u7c73\u9897\u7c92\u7684\u8868\u9762\u3002\u5e76\u4e14\u901a\u8fc7\u7fa7\u57fa\u6216\u8005\u6c28\u57fa\uff0c\u6c28\u57fa\u9178\u8fd8\u80fd\u4e0e\u91d1\u5c5e\u79bb\u5b50\u53d1\u751f\u5f3a\u70c8\u7684\u4f5c\u7528\u3002\u56e0\u6b64\uff0c\u57fa\u4e8e\u94f6\u79bb\u5b50\u53ef\u4e0e\u8d56\u6c28\u9178\u6216\u7cbe\u6c28\u9178\u4e0a\u7684\u6c28\u57fa\u6216\u8005\u7fa7\u57fa\u8fdb\u884c\u914d\u4f4d\u7684\u73b0\u8c61\uff0c\u53ef\u5c06\u7cbe\u6c28\u9178\u4fee\u9970\u91d1\u7eb3\u7c73\u9897\u7c92\uff0c\u518d\u5229\u7528\u94f6\u79bb\u5b50\u5f15\u53d1\u4fee\u9970\u91d1\u7eb3\u7c73\u9897\u7c92\u7684\u96c6\u805a\u3002\u6b64\u5916\uff0c\u534a\u80f1\u6c28\u9178\u540c\u65f6\u62e5\u6709\u5def\u57fa\u3001\u6c28\u57fa\u548c\u7fa7\u57fa\u3002\u8fd9\u6837\u4e00\u6765\uff0c\u901a\u8fc7Au-S\u952e\uff0c\u534a\u80f1\u6c28\u9178\u53ef\u4ee5\u975e\u5e38\u5bb9\u6613\u7684\u4e0e\u7eb3\u7c73\u9897\u7c92\u8868\u9762\u7ed3\u5408\uff0c\u540c\u65f6\u53c8\u80fd\u901a\u8fc7\u5e26\u7535\u57fa\u56e2\u4e4b\u95f4\u7684\u9759\u7535\u4f5c\u7528\u5c06\u91d1\u7eb3\u7c73\u9897\u7c92\u96c6\u805a\u8d77\u6765\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-62176\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2017\/01\/\u56fe3-1.jpeg\" alt=\"\" width=\"700\" height=\"331\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2017\/01\/\u56fe3-1.jpeg 700w, \/\/m.iemloyee.com\/wp-content\/uploads\/2017\/01\/\u56fe3-1-300x142.jpeg 300w\" sizes=\"(max-width: 700px) 100vw, 700px\" \/><\/p>\n<p style=\"text-align: center;\"><strong>\u56fe<\/strong><strong>3<\/strong> \u751f\u5316\u5206\u6790\u8fc7\u7a0b\u4e2d\u6c28\u57fa\u9178\u4ecb\u5bfc\u7684\u91d1\u7eb3\u7c73\u9897\u7c92\u8868\u9762\u4fee\u9970<\/p>\n<p><strong>2.2.2 <\/strong><strong>\u5def\u57fa\u5316\u5408\u7269\u4ecb\u5bfc\u7684\u8868\u9762\u4fee\u9970<\/strong><\/p>\n<p>\u87ba\u5421\u5583\uff08spiropyran\uff09\u4e0e\u94dc\u79bb\u5b50\u4e4b\u95f4\u7684\u87af\u5408\u4f5c\u7528\u53ef\u4ee5\u901a\u8fc7\u7d2b\u5916\u5149\u8fdb\u884c\u63a7\u5236\uff0c\u56e0\u6b64\u53ef\u4ee5\u6784\u5efa\u87ba\u5421\u5583-\u91d1\u7eb3\u7c73\u9897\u7c92\u6765\u5236\u9020\u57fa\u4e8e\u91d1\u7eb3\u7c73\u9897\u7c92\u805a\u96c6\u7684\u53ef\u5b9e\u73b0\u91cd\u7f6e\u548c\u591a\u6837\u5316\u8bfb\u53d6\u529f\u80fd\u7684\u903b\u8f91\u7cfb\u7edf\u3002\u53e6\u5916\uff0c\u5feb\u901f\u76f4\u63a5\u63a2\u6d4b\u4e09\u4ef7\u91d1\u5c5e\u79bb\u5b50\u4e5f\u662f\u4e00\u9879\u975e\u5e38\u91cd\u8981\u5e76\u4e14\u6781\u5177\u6311\u6218\u6027\u7684\u5de5\u4f5c\u3002\u4e3a\u4e86\u514b\u670d\u8fd9\u9879\u6311\u6218\uff0c\u53ef\u4ee5\u5229\u7528\u4e24\u6027\u79bb\u5b50\u578b\u5206\u5b50\uff08zwitterionic molecule\uff09\u4fee\u9970\u91d1\u7eb3\u7c73\u9897\u7c92\u3002\u56e0\u4e3a\u5206\u5b50\u95f4\u7684\u4e24\u6027\u79bb\u5b50\u578b\u8868\u9762\u7684\u5b58\u5728\uff0c\u4e09\u4ef7\u91d1\u5c5e\u79bb\u5b50\u53ef\u4ee5\u8bf1\u53d1\u5e26\u6709\u989c\u8272\u53d8\u5316\u7684\u7eb3\u7c73\u9897\u7c92\u96c6\u805a\u3002\u4e0d\u4ec5\u5982\u6b64\uff0c\u901a\u8fc7\u8c03\u8282\u9178\u78b1\u5ea6\u8fd8\u80fd\u8c03\u6574\u4e09\u4ef7\u79bb\u5b50\u7684\u72b6\u6001\u4ece\u800c\u5b9e\u73b0\u4e24\u6027\u79bb\u5b50\u578b\u91d1\u7eb3\u7c73\u9897\u7c92\u7684\u56de\u6536\u518d\u5229\u7528\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-62177\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2017\/01\/\u56fe4-1.jpeg\" alt=\"\" width=\"700\" height=\"513\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2017\/01\/\u56fe4-1.jpeg 700w, \/\/m.iemloyee.com\/wp-content\/uploads\/2017\/01\/\u56fe4-1-300x220.jpeg 300w\" sizes=\"(max-width: 700px) 100vw, 700px\" \/><\/p>\n<p style=\"text-align: center;\"><strong>\u56fe<\/strong><strong>4<\/strong> \u57fa\u4e8e\u5def\u57fa\u5316\u5408\u7269\u4fee\u9970\u91d1\u7eb3\u7c73\u9897\u7c92\u7684\u53ef\u89c6\u5316\u751f\u7269\u4f20\u611f\u5668<\/p>\n<p><strong>2.3 <\/strong><strong>\u57fa\u4e8e\u914d\u4f53\u4ea4\u6362\uff08<\/strong><strong>ligand exchange reaction<\/strong><strong>\uff09\u7684\u8868\u9762\u4fee\u9970<\/strong><\/p>\n<p>\u91d1\u7eb3\u7c73\u9897\u7c92\u8868\u9762\u4fee\u9970\u7b56\u7565\u4e2d\u7684\u914d\u4f53\u4ea4\u6362\u65b9\u6cd5\u662f\u6784\u5efa\u751f\u7269\u4f20\u611f\u5668\u7684\u9ad8\u6548\u7b56\u7565\u3002\u8fd9\u79cd\u65b9\u6cd5\u4e3b\u8981\u7528\u6765\u63a2\u6d4b\u94f6\u7eb3\u7c73\u7c92\u5b50\u548c\u4e00\u4e9b\u91cd\u8981\/\/m.iemloyee.com\/wp-admin\/post.php?post=62173&amp;action=edit\u7684\u751f\u5316\u6807\u8bb0\u7269\uff08biochemical markers\uff09\u3002\u6bd4\u5982\u8bf4\u7ecf\u8fc7\u672b\u7aef\u5e26\u6709\u5b63\u94f5\u7684\u786b\u9187\u4fee\u9970\u540e\u7684\u91d1\u7eb3\u7c73\u9897\u7c92\u5728\u9178\u6027\u6eb6\u6db2\u4e2d\u53ef\u4ee5\u51ed\u7740\u9759\u7535\u6392\u65a5\u4f5c\u7528\u800c\u7a33\u5b9a\u5b58\u5728\uff0c\u800c\u7531\u4e8e\u94f6\u79bb\u5b50\u6bd4\u5b63\u94f5\u57fa\u56e2\u66f4\u5bb9\u6613\u4e0e\u5def\u57fa\u4f5c\u7528\uff0c\u4e8e\u662f\u94f6\u79bb\u5b50\u53ef\u4ee5\u53d6\u4ee3\u91d1\u7eb3\u7c73\u9897\u7c92\u4e0a\u7684\u5b63\u94f5\u57fa\u56e2\u5e76\u5bfc\u81f4\u9897\u7c92\u7684\u96c6\u805a\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-62178\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2017\/01\/\u56fe5-1.jpeg\" alt=\"\" width=\"700\" height=\"530\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2017\/01\/\u56fe5-1.jpeg 700w, \/\/m.iemloyee.com\/wp-content\/uploads\/2017\/01\/\u56fe5-1-300x227.jpeg 300w\" sizes=\"(max-width: 700px) 100vw, 700px\" \/><\/p>\n<p style=\"text-align: center;\"><strong>\u56fe<\/strong><strong>5<\/strong> \u91d1\u7eb3\u7c73\u9897\u7c92\u7684\u914d\u4f53\u4ea4\u6362\u8868\u9762\u4fee\u9970\u7b56\u7565<\/p>\n<p><strong>3.\u8ba8\u8bba\u4e0e\u5c55\u671b<\/strong><\/p>\n<p>\u57fa\u4e8e\u91d1\u7eb3\u7c73\u9897\u7c92\u7684\u751f\u5316\u5206\u6790\u5177\u6709\u6210\u4e3a\u4e0b\u4e00\u4ee3\u5206\u6790\u6280\u672f\u7684\u6f5c\u529b\uff0c\u7136\u800c\u76ee\u524d\u8fd9\u4e00\u6280\u672f\u4f9d\u7136\u5b58\u5728\u7740\u8bf8\u591a\u7684\u95ee\u9898\u3002\u4e3a\u4e86\u5b9e\u73b0\u8fd9\u4e00\u65b0\u578b\u5206\u6790\u65b9\u6cd5\u4ece\u5b9e\u9a8c\u5ba4\u5f00\u53d1\u5230\u5b9e\u9645\u5e94\u7528\u573a\u666f\u7684\u8f6c\u53d8\uff0c\u4f9d\u7136\u9700\u8981\u505a\u51fa\u8bb8\u591a\u52aa\u529b\uff1a<\/p>\n<p>\uff081\uff09\u4e00\u7cfb\u5217\u7684\u8868\u9762\u5316\u5b66\u7b56\u7565\u5305\u62ec\u5c01\u7aef\u5242\uff08capping agent\uff09\u53ca\u5176\u751f\u7269\u5076\u8054\u65b9\u6cd5\u5728\u5185\u5747\u9700\u8981\u66f4\u8fdb\u4e00\u6b65\u7684\u53d1\u5c55\uff0c\u56e0\u4e3a\u8fd9\u7c7b\u5c01\u7aef\u5242\u80fd\u591f\u7a33\u5b9a\u91d1\u7eb3\u7c73\u9897\u7c92\u5728\u590d\u6742\u751f\u7269\u6837\u54c1\u73af\u5883\u4e2d\u7684\u6027\u80fd\uff0c\u5bf9\u68c0\u6d4b\u8d28\u91cf\u7684\u63d0\u9ad8\u81f3\u5173\u91cd\u8981\u3002<\/p>\n<p>\uff082\uff09\u4e3a\u4e86\u5b9e\u73b0\u9ad8\u6548\u3001\u4f4e\u6210\u672c\u3001\u89c4\u6a21\u5316\u7684\u91d1\u7eb3\u7c73\u9897\u7c92\u8868\u9762\u4fee\u9970\uff0c\u53ef\u5f15\u8fdb\u5fae\u6d41\u63a7\u7cfb\u7edf\u53c2\u4e0e\u4ea7\u54c1\u7684\u751f\u4ea7\u8fc7\u7a0b\u3002<\/p>\n<p>\uff083\uff09\u65b0\u578b\u7684\u7eb3\u7c73\u6750\u6599\u548c\u65b0\u578b\u7684\u53cd\u5e94\u7c7b\u578b\u5747\u80fd\u4e3a\u8868\u9762\u4fee\u9970\u63d0\u4f9b\u66f4\u591a\u7684\u7b56\u7565\u9009\u62e9\uff0c\u80fd\u591f\u4fc3\u8fdb\u65b0\u578b\u5206\u6790\u5de5\u5177\u7684\u51fa\u73b0\u548c\u53d1\u5c55\u3002<\/p>\n<p>\u6587\u732e\u94fe\u63a5\uff1a<a href=\"http:\/\/pubs.acs.org\/doi\/full\/10.1021\/acs.accounts.6b00506#showFigures\" target=\"_blank\"> Surface Modification of Gold Nanoparticles with Small Molecules for Biochemical Analysis<\/a>(Acc. Chem. Res., 2017, DOI: 10.1021\/acs.accounts.6b00506)<\/p>\n<p>\u672c\u6587\u7531\u6750\u6599\u4eba\u7f16\u8f91\u90e8\u5b66\u672f\u7ec4cailiaoniuer\u63d0\u4f9b\uff0c\u6750\u6599\u725b\u7f16\u8f91\u6574\u7406\u3002<\/p>\n<p>\u6750\u6599\u725b\u7f51\u4e13\u6ce8\u4e8e\u8ddf\u8e2a\u6750\u6599\u9886\u57df\u79d1\u6280\u53ca\u884c\u4e1a\u8fdb\u5c55\uff0c\u8fd9\u91cc\u6c47\u96c6\u4e86\u5404\u5927\u9ad8\u6821\u7855\u535a\u751f\u3001\u4e00\u7ebf\u79d1\u7814\u4eba\u5458\u4ee5\u53ca\u884c\u4e1a\u4ece\u4e1a\u8005\uff0c\u5982\u679c\u60a8\u5bf9\u4e8e\u8ddf\u8e2a\u6750\u6599\u9886\u57df\u79d1\u6280\u8fdb\u5c55\uff0c\u89e3\u8bfb\u9ad8\u6c34\u5e73\u6587\u7ae0\u6216\u662f\u8bc4\u8ff0\u884c\u4e1a\u6709\u5174\u8da3\uff0c<a href=\"\/\/m.iemloyee.com\/25127.html\" target=\"_blank\">\u70b9\u6211\u52a0\u5165\u6750\u6599\u4eba\u7f16\u8f91\u90e8<\/a>\u3002<\/p>\n<p>\u6750\u6599\u6d4b\u8bd5\uff0c\u6570\u636e\u5206\u6790\uff0c\u4e0a<a href=\"http:\/\/www.ceshigu.com\/\" target=\"_blank\">\u6d4b\u8bd5\u8c37<\/a>\uff01<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u3010\u5f15\u8bed\u3011 \u751f\u5316\u5206\u6790\uff08biochemical analysis\uff09\u5982\u4eca\u5728\u4e34\u5e8a\u8bca\u65ad\u3001\u98df\u54c1\u5b89\u5168\u4ee5\u53ca\u73af\u5883\u76d1\u6d4b\u7b49\u9886\u57df\u53d1\u6325\u7740\u8d8a\u6765\u8d8a\u91cd\u8981\u7684\u4f5c\u7528\u3002\u800c\u57fa\u4e8e\u7eb3\u7c73\u9897\u7c92\u7684\u751f\u5316\u5206\u6790\u6280\u672f\u968f\u7740&#8230;<\/p>\n","protected":false},"author":1076,"featured_media":62174,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[533],"tags":[33],"class_list":["post-62173","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-zongshu","tag-nano"],"_links":{"self":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts\/62173"}],"collection":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/users\/1076"}],"replies":[{"embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=62173"}],"version-history":[{"count":9,"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts\/62173\/revisions"}],"predecessor-version":[{"id":62557,"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts\/62173\/revisions\/62557"}],"wp:featuredmedia":[{"embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/media\/62174"}],"wp:attachment":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=62173"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=62173"},{"taxonomy":"post_tag","embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=62173"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}