{"id":52241,"date":"2016-11-19T06:30:23","date_gmt":"2016-11-18T22:30:23","guid":{"rendered":"\/\/m.iemloyee.com\/?p=52241"},"modified":"2016-11-18T21:48:35","modified_gmt":"2016-11-18T13:48:35","slug":"%e9%85%b6%ef%bc%8c%e5%bc%80%e5%90%af%e5%8f%af%e9%99%8d%e8%a7%a3%e5%a1%91%e6%96%99%e4%b9%8b%e9%97%a8","status":"publish","type":"post","link":"\/\/m.iemloyee.com\/?p=52241","title":{"rendered":"\u9176\uff0c\u5f00\u542f\u53ef\u964d\u89e3\u5851\u6599\u4e4b\u95e8"},"content":{"rendered":"<p><strong>\u6750\u6599\u725b\u6ce8\uff1a<\/strong><span style=\"color: #333333;\">\u81ea\u5851\u6599\u4ea7\u54c1\u8d70\u8fdb\u6211\u4eec\u7684\u751f\u6d3b\u4ee5\u6765\uff0c\u201c\u767d\u8272\u6c61\u67d3\u201d\u5c31\u5f00\u59cb\u65e0\u5904\u4e0d\u5728\u3002\u4f7f\u7528\u53ef\u964d\u89e3\u5851\u6599\u662f\u4e00\u4e2a\u7edd\u4f73\u7684\u89e3\u51b3\u65b9\u6848\uff0c\u800c\u9176\u5728\u5176\u4e2d\u626e\u6f14\u7740\u91cd\u8981\u7684\u89d2\u8272\u3002<\/span><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-52243\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2016\/11\/plasticimage2ee.png\" alt=\"plasticimage2ee\" width=\"615\" height=\"467\" \/><\/p>\n<p>MIT\u7684\u5316\u5b66\u5bb6\u4eec\u6b63\u5728\u7814\u7a76\u8c03\u6574\u4e00\u79cd\u9176\u7ed3\u6784\u3002\u5b83\u80fd\u591f\u50ac\u5316\u53ef\u964d\u89e3\u5851\u6599\u7684\u5408\u6210\uff0c\u5bf9\u4e8e\u63a8\u5e7f\u5546\u4e1a\u5316\uff0c\u4fdd\u62a4\u5730\u7403\u73af\u5883\u6709\u7740\u91cd\u8981\u7684\u610f\u4e49\u3002\u5728\u9176\u7684\u50ac\u5316\u4e0b\uff0c\u9996\u5148\u5f62\u6210\u4e00\u6761\u9ad8\u5206\u5b50\u957f\u94fe\uff0c\u7136\u540e\u6839\u636e\u8d77\u59cb\u539f\u6599\u7684\u4e0d\u540c\u5f62\u6210\u786c\u6027\u6216\u8005\u8f6f\u6027\u5851\u6599\u3002\u4e86\u89e3\u9176\u7684\u7ed3\u6784\u80fd\u591f\u8fdb\u4e00\u6b65\u63a7\u5236\u5851\u6599\u6210\u5206\u548c\u5c3a\u5bf8\uff0c\u8fd9\u662f\u5c06\u5176\u5546\u4e1a\u5316\u7684\u5fc5\u7ecf\u4e4b\u8def\u3002<\/p>\n<p>\u6559\u6388Catherine Drennan\u662fMIT\u5316\u5b66\u751f\u7269\u65b9\u5411\u7684\u4e13\u5bb6\uff0c\u4ed6\u8bf4\uff1a\u201c\u6211\u5e0c\u671b\u6211\u4eec\u80fd\u591f\u4ece\u5927\u81ea\u7136\u4e2d\u83b7\u5f97\u542f\u793a\uff0c\u5e76\u4ee5\u6b64\u6765\u6539\u5584\u6211\u4eec\u7684\u751f\u5b58\u5bb6\u56ed\u3002\u5728\u8bbe\u8ba1\u548c\u6539\u9020\u9176\u4e4b\u524d\uff0c\u6211\u4eec\u4e00\u5b9a\u8981\u5145\u5206\u5730\u4e86\u89e3\u5b83\u7684\u7ed3\u6784\u3002\u201d<\/p>\n<p>\u6b64\u9879\u6210\u679c\u53d1\u8868\u5728\u671f\u520a<em>Journal of Biological Chemistry<\/em>\u4e0a\uff0c\u8d44\u6df1\u5b66\u8005Drennan\u548cJoAnne Stubbe\u662f\u5176\u4e2d\u7684\u4e24\u4f4d\u4f5c\u8005\uff0c\u7b2c\u4e00\u4f5c\u8005\u662f\u540d\u4e3aElizabeth Wittenborn\u7684\u7814\u7a76\u751f\u3002<\/p>\n<p><strong>\u590d\u6742\u7684\u7ed3\u6784<\/strong><\/p>\n<p>\u805a\u7f9f\u57fa\u70f7\u916f\uff08PHA\uff09\u5408\u6210\u9176\u662f\u4e00\u79cd\u975e\u5e38\u666e\u901a\u7684\u9176\uff0c\u5b83\u5b58\u5728\u4e8e\u5927\u591a\u6570\u7ec6\u83cc\u7684\u5185\u90e8\u3002\u8fd9\u79cd\u9176\u80fd\u591f\u5408\u6210\u4e00\u79cd\u7279\u6b8a\u7684\u805a\u5408\u7269\uff0c\u7528\u6765\u5728\u98df\u7269\u7f3a\u4e4f\u7684\u72b6\u6001\u4e0b\u5b58\u50a8\u78b3\u5143\u7d20\u3002\u6bd4\u5982\u94a9\u866b\u8d2a\u94dc\u83cc\u80fd\u591f\u901a\u8fc7\u8fd9\u79cd\u9176\u5b58\u50a8\u76f8\u5f53\u4e8e\u81ea\u8eab\u5e72\u91cd85%\u7684\u201c\u98df\u7269\u201d\u3002<\/p>\n<p>\u91c7\u7528\u4e0d\u540c\u7684\u8d77\u59cb\u539f\u6599\uff0c\u5c31\u4f1a\u5f97\u5230\u4e0d\u540c\u7c7b\u578b\u7684\u5851\u6599\uff0c\u800c\u8fd9\u4e9b\u8d77\u59cb\u539f\u6599\u901a\u5e38\u662f\u70f7\u70c3\u57fa\u8f85\u9176A\u7684\u4e00\u79cd\u6216\u51e0\u79cd\u884d\u751f\u7269\uff08\u70f7\u70c3\u662f\u4e00\u79cd\u5316\u5b66\u57fa\u56e2\uff0c\u5b83\u80fd\u591f\u51b3\u5b9a\u805a\u5408\u7269\u7684\u6027\u8d28\uff09\u3002\u5236\u5f97\u7684\u5851\u6599\u7c7b\u578b\u4e5f\u591a\u79cd\u591a\u6837\uff0c\u6709\u786c\u6027\u5851\u6599\uff0c\u8f6f\u6027\u5851\u6599\uff0c\u4ee5\u53ca\u7c7b\u4f3c\u6a61\u80f6\u7684\u5f39\u6027\u5851\u6599\u3002<\/p>\n<p>\u5316\u5b66\u5bb6\u548c\u5316\u5b66\u5de5\u7a0b\u5e08\u4eec\u5bf9PHA\u5408\u6210\u9176\u6709\u7740\u6781\u5927\u7684\u5174\u8da3\uff0c\u56e0\u4e3a\u5b83\u80fd\u53ef\u63a7\u5730\u5c063000\u4e2a\u5355\u4f53\u7cbe\u786e\u5730\u8fde\u7ed3\u8d77\u6765\u3002Stubbe\u8bf4\uff1a\u201c\u5728\u8fd9\u79cd\u60c5\u51b5\u4e0b\uff0c\u81ea\u7136\u754c\u80fd\u591f\u5408\u6210\u51fa\u8d85\u5927\u7684\u805a\u5408\u7269\uff0c\u6bd4\u4eba\u7c7b\u5408\u6210\u7684\u4efb\u4f55\u4e00\u79cd\u805a\u5408\u7269\u90fd\u8981\u5927\uff0c\u5b83\u4eec\u6709\u7740\u540c\u6837\u7684\u5206\u5b50\u91cd\u91cf\uff0c\u5982\u6b64\u72ec\u7279\u65b0\u5947\u3002\u201d<\/p>\n<p>\u7531\u4e8e\u8fd9\u79cd\u86cb\u767d\u8d28\u5f88\u96be\u7ed3\u6676\uff0c\u6240\u4ee5\u867d\u7136Drennan, Stubbe\u4ee5\u53ca\u4f17\u591a\u79d1\u5b66\u5bb6\u5df2\u7ecf\u7814\u7a76\u8fd9\u79cd\u9176\u7ed3\u6784\u5f88\u4e45\u4e86\uff0c\u4f46\u662f\u5176\u7ed3\u6784\u4ecd\u7136\u590d\u6742\u96be\u61c2\u3002\u6211\u4eec\u77e5\u9053\uff0c\u82e5\u60f3\u901a\u8fc7XRD\u7814\u7a76\u86cb\u767d\u8d28\u7684\u5206\u5b50\u539f\u5b50\u7ed3\u6784\uff0c\u7ed3\u6676\u7684\u6b65\u9aa4\u5fc5\u4e0d\u53ef\u5c11\u3002<\/p>\n<p>Marco Jost and Yifeng Wei\u4e5f\u662f\u8be5\u6210\u679c\u7684\u5408\u4f5c\u4f5c\u8005\uff0c\u4ed6\u4eec\u662fMIT\u7684\u5386\u5c4a\u7814\u7a76\u751f\u3002\u6bd5\u4e1a\u4e4b\u524d\u4ed6\u4eec\u7814\u7a76\u4e86\u5173\u4e8e\u7ed3\u6676\u7684\u8bfe\u9898\uff0c\u5e76\u5728\u6bd5\u4e1a\u4e4b\u524d\u6210\u529f\u5b8c\u6210\u3002<\/p>\n<p>\u4e00\u65e6\u6709\u4e86\u6676\u4f53\u7ed3\u6784\u6570\u636e\uff0c\u4e00\u5207\u8fce\u5203\u800c\u89e3\u3002Wittenborn\u5206\u6790\u4e86\u8fd9\u4e9b\u6676\u4f53\u5b66\u6570\u636e\uff0c\u60f3\u51fa\u4e86\u8fd9\u79cd\u9176\u7ed3\u6784\u3002\u5206\u6790\u663e\u793a\uff0cPHA\u5408\u6210\u9176\u542b\u6709\u4e24\u4e2a\u5b8c\u5168\u4e00\u6837\u7684\u5355\u5143\u7ed3\u6784\uff0c\u5373\u5f62\u6210\u4e00\u4e2a\u4e8c\u805a\u4f53\u3002\u6bcf\u4e00\u4e2a\u5355\u5143\u90fd\u6709\u4e00\u4e2a\u7f29\u805a\u53cd\u5e94\u7684\u6d3b\u6027\u4f4d\u70b9\uff0c\u56e0\u6b64\u63a8\u7ffb\u4e86\u4e4b\u524d\u7684\u63a8\u6d4b\uff1a\u6d3b\u6027\u4f4d\u70b9\u5904\u4e8e\u4e8c\u805a\u7269\u7684\u8868\u9762\u3002<\/p>\n<p>\u5206\u6790\u8fd8\u6307\u51fa\uff0c\u8fd9\u79cd\u9176\u6709\u4e24\u4e2a\u7aef\u53e3\uff0c\u4e00\u4e2a\u662f\u8d77\u59cb\u539f\u6599\u7684\u8fdb\u5165\u7aef\uff0c\u4e00\u4e2a\u662f\u805a\u5408\u7269\u957f\u94fe\u7684\u7ed3\u675f\u7aef\u3002<\/p>\n<p>Stubbe\u8bf4\uff1a\u201c\u8f85\u9176A\u4f5c\u4e3a\u5e95\u7269\uff0c\u9700\u53ca\u65f6\u9000\u51fa\u4ee5\u5f15\u5165\u5355\u4f53\u3002\u8fd9\u4e2a\u53cd\u5e94\u5305\u542b\u4e86\u8bb8\u591a\u8fd0\u52a8\u8fc7\u7a0b\uff0c\u5341\u5206\u6709\u8da3\u3002\u201d<\/p>\n<p>\u8fdb\u5165\u901a\u9053\u7684\u4f4d\u7f6e\u5341\u5206\u660e\u663e\uff0c\u6b64\u5904\u6709\u4e00\u4e2a\u5927\u7684\u5b54\u6d1e\uff0c\u5468\u56f4\u6709\u4fdd\u5b88\u6c28\u57fa\u9178\u3002\u9000\u51fa\u901a\u9053\u7684\u5b54\u6d1e\u5f88\u5c0f\uff0c\u56e0\u6b64\u96be\u4ee5\u53d1\u73b0\u3002\u4f46\u5b83\u7684\u5468\u56f4\u4e5f\u73af\u7ed5\u7740\u4fdd\u5b88\u6c28\u57fa\u9178\uff0c\u56e0\u6b64\u6700\u7ec8\u4e5f\u88ab\u627e\u5230\u3002<\/p>\n<p>Wittenborn\u8bf4\uff1a\u201c\u9000\u51fa\u901a\u9053\u5904\u7684\u4fdd\u5b88\u6c28\u57fa\u9178\u7b49\u5f62\u6210\u4e86\u4e00\u4e2a\u5f27\u5f62\u7684\u7f51\u72b6\u7ed3\u6784\uff0c\u5b83\u4eec\u51e0\u4e4e\u5c06\u72ed\u7a84\u7684\u901a\u9053\u5305\u56f4\u8d77\u6765\u3002\u6211\u4eec\u63a8\u6d4b\u5b83\u5728\u805a\u5408\u7269\u901a\u8fc7\u7ba1\u9053\u65f6\uff0c\u8d77\u5230\u4e86\u4fdd\u62a4\u86cb\u767d\u8d28\u7684\u4f5c\u7528\u3002\u201d<\/p>\n<p><strong>\u65b0\u6846\u67b6<\/strong><\/p>\n<p>\u9176\u7684\u7ed3\u6784\u5bf9\u4e8e\u57fa\u5e95\u548c\u4ea7\u7269\u81f3\u5173\u91cd\u8981\uff0c\u56e0\u6b64Drennan\u7684\u5b9e\u9a8c\u5ba4\u8ba1\u5212\u7814\u7a76PHA\u9176\u7ed3\u6784\uff0c\u83b7\u5f97\u66f4\u591a\u66f4\u91cd\u8981\u7684\u4fe1\u606f\uff0c\u4ece\u800c\u7814\u7a76\u5b83\u7684\u5de5\u4f5c\u673a\u7406\u3002Drennan\u8bf4\uff1a\u201c\u8fd9\u662f\u5b66\u4e60\u8fd9\u4e9b\u9176\u7cfb\u7edf\u7684\u5f00\u7aef\uff0c\u6211\u4eec\u505a\u7684\u6bcf\u4e00\u4e2a\u5b9e\u9a8c\u90fd\u4f1a\u52a0\u6df1\u6211\u4eec\u5bf9\u5b83\u7684\u7406\u89e3\u3002\u201d<\/p>\n<p>\u4e00\u4e9b\u751f\u7269\u79d1\u6280\u516c\u53f8\u5f00\u59cb\u4f7f\u7528PHA\u5408\u6210\u9176\u7b49\u5176\u5b83\u9176\u7c7b\u5236\u5907\u5851\u6599\u5236\u54c1\uff0c\u6709\u4e00\u5bb6\u516c\u53f8\u6b63\u5728\u7528\u5176\u751f\u4ea7\u533b\u7597\u7528\u54c1\u3002\u5c3d\u7ba1\u5728\u5f88\u5927\u7a0b\u5ea6\u4e0a\u4e0e\u4f20\u7edf\u7684\u5851\u6599\u5236\u54c1\u76f8\u6bd4\uff0c\u8fd9\u6837\u505a\u662f\u4e0d\u5408\u7b97\u7684\uff0c\u4f46\u662f\u7528\u8fd9\u79cd\u9176\u5408\u6210\u7684\u805a\u5408\u7269\u53ef\u4ee5\u7528\u4e8e\u7279\u6b8a\u7684\u9886\u57df\uff0c\u5982\u4e13\u7528\u805a\u5408\u7269\u6dfb\u52a0\u5242\uff0c\u4e73\u80f6\u4ee5\u53ca\u4e00\u4e9b\u533b\u5b66\u5e94\u7528\u3002<\/p>\n<p>\u867d\u7136\u4e86\u89e3\u9176\u7684\u7ed3\u6784\u4fe1\u606f\u5bf9\u4e8e\u964d\u4f4e\u6210\u672c\u4f5c\u7528\u4e0d\u5927\uff0c\u4f46\u5b83\u80fd\u591f\u4e3a\u5f00\u53d1\u65b0\u6750\u6599\u548c\u65b0\u7528\u9014\u63d0\u4f9b\u53ef\u80fd\u3002Kristi Snell\u662f\u4e00\u5bb6\u6709\u540d\u7684\u751f\u7269\u79d1\u6280\u516c\u53f8\u7684\u526f\u7406\u4e8b\u957f\uff0c\u4ed6\u8bf4\uff1a\u201c\u9176\u7684\u7ed3\u6784\u548c\u50ac\u5316\u673a\u7406\u80fd\u4e3a\u7814\u7a76\u4eba\u5458\u5f00\u53d1\u65b0\u6750\u6599\u63d0\u4f9b\u65b0\u7684\u65b9\u5411\u3002\u201d<\/p>\n<p>\u539f\u6587\u94fe\u63a5\uff1a<a href=\"http:\/\/www.eedesignit.com\/enzyme-tweaking-leads-to-biodegradable-plastics\/\" target=\"_blank\">Enzyme tweaking leads to biodegradable plastics<\/a>.<\/p>\n<p>\u6587\u732e\u94fe\u63a5\uff1a<a href=\"http:\/\/www.jbc.org\/search?fulltext=enzyme&amp;author1=Elizabeth+Wittenborn&amp;pubdate_year=2016&amp;volume=&amp;firstpage=&amp;submit=yes\" target=\"_blank\">Structure of the Catalytic Domain of the Class I Polyhydroxybutyrate Synthase from Cupriavidus necator<\/a>.<\/p>\n<p>\u672c\u6587\u7531\u7f16\u8f91\u90e8\u6768\u6811\u63d0\u4f9b\u7d20\u6750\uff0c\u738b\u601d\u8fea\u7f16\u8bd1\uff0c<a href=\"\/\/m.iemloyee.com\/25127.html\" target=\"_blank\">\u70b9\u6211\u52a0\u5165\u6750\u6599\u4eba\u7f16\u8f91\u90e8<\/a>\u3002<\/p>\n<p>\u6750\u6599\u6d4b\u8bd5\uff0c\u6570\u636e\u5206\u6790\uff0c\u4e0a<a href=\"http:\/\/www.ceshigu.com\/\" target=\"_blank\">\u6d4b\u8bd5\u8c37<\/a>\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u6750\u6599\u725b\u6ce8\uff1a\u81ea\u5851\u6599\u4ea7\u54c1\u8d70\u8fdb\u6211\u4eec\u7684\u751f\u6d3b\u4ee5\u6765\uff0c\u201c\u767d\u8272\u6c61\u67d3\u201d\u5c31\u5f00\u59cb\u65e0\u5904\u4e0d\u5728\u3002\u4f7f\u7528\u53ef\u964d\u89e3\u5851\u6599\u662f\u4e00\u4e2a\u7edd\u4f73\u7684\u89e3\u51b3\u65b9\u6848\uff0c\u800c\u9176\u5728\u5176\u4e2d\u626e\u6f14\u7740\u91cd\u8981\u7684\u89d2\u8272\u3002 MIT\u7684\u5316\u5b66\u5bb6\u4eec\u6b63\u5728\u7814\u7a76\u8c03&#8230;<\/p>\n","protected":false},"author":284,"featured_media":52243,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2],"tags":[],"class_list":["post-52241","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-keji"],"_links":{"self":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts\/52241"}],"collection":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/users\/284"}],"replies":[{"embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=52241"}],"version-history":[{"count":5,"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts\/52241\/revisions"}],"predecessor-version":[{"id":52551,"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts\/52241\/revisions\/52551"}],"wp:featuredmedia":[{"embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/media\/52243"}],"wp:attachment":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=52241"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=52241"},{"taxonomy":"post_tag","embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=52241"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}