{"id":43079,"date":"2016-10-05T14:00:23","date_gmt":"2016-10-05T06:00:23","guid":{"rendered":"\/\/m.iemloyee.com\/?p=43079"},"modified":"2016-09-30T20:38:28","modified_gmt":"2016-09-30T12:38:28","slug":"%e9%a1%b6%e5%88%8a%e5%8a%a8%e6%80%81-nature%e5%ad%90%e5%88%8aampnas%e7%ad%89%e7%94%9f%e7%89%a9%e6%9d%90%e6%96%99%e5%89%8d%e6%b2%bf%e6%9c%80%e6%96%b0%e7%a7%91%e7%a0%94%e6%88%90%e6%9e%9c%e7%b2%be","status":"publish","type":"post","link":"\/\/m.iemloyee.com\/?p=43079","title":{"rendered":"\u9876\u520a\u52a8\u6001 | Nature\u5b50\u520a\/AM\/PNAS\u7b49\u751f\u7269\u6750\u6599\u524d\u6cbf\u6700\u65b0\u79d1\u7814\u6210\u679c\u7cbe\u9009\u3010\u7b2c24\u671f\u3011"},"content":{"rendered":"

1\u3001Adv. Mater. \u751f\u7269\u6a21\u62df\u764c\u7ec6\u80de\u7684\u7eb3\u7c73\u9897\u7c92\u5b9e\u73b0\u540c\u7c7b\u578b\u764c\u7ec6\u80de\u7684\u9776\u5411\u6cbb\u7597<\/strong><\/p>\n

\"\u56fe\u72471\"<\/p>\n

\u56fe1 <\/strong>\u751f\u7269\u6a21\u62df\u764c\u7ec6\u80de\u7684\u7eb3\u7c73\u9897\u7c92\u5b9e\u73b0\u540c\u7c7b\u578b\u764c\u7ec6\u80de\u7684\u9776\u5411\u6cbb\u7597\u7684\u793a\u610f\u56fe<\/p>\n

\u6700\u8fd1\uff0c\u4e2d\u56fd\u79d1\u5b66\u9662\u4e0a\u6d77\u836f\u7269\u7814\u7a76\u6240\u674e\u4e9a\u5e73\u7814\u7a76\u5458\uff08\u901a\u8baf\u4f5c\u8005\uff09\u548c\u6c88\u9633\u836f\u79d1\u5927\u5b66\u836f\u5b66\u9662\u738b\u601d\u73b2\u6559\u6388\uff08\u901a\u8baf\u4f5c\u8005\uff09\u5f00\u53d1\u51fa\u4e00\u79cd\u65b0\u7684\u7eb3\u7c73\u836f\u7269\u8d1f\u8f7d\u7cfb\u7edf\uff0c\u5b9e\u73b0\u4e86\u540c\u7c7b\u578b\u764c\u7ec6\u80de\u7684\u9776\u5411\u6cbb\u7597\u3002\u8fd9\u79cd\u7eb3\u7c73\u836f\u7269\u8d1f\u8f7d\u7cfb\u7edf\u4ee54T1\u4e73\u817a\u764c\u7ec6\u80de\u819c\u4f5c\u4e3a\u5916\u58f3\uff0c\u8d1f\u8f7d\u7d2b\u6749\u9187\u836f\u7269\u7684\u9ad8\u5206\u5b50\u4f5c\u4e3a\u4e2d\u5fc3\u6838\uff0c\u80fd\u51cf\u5c11\u5de8\u566c\u7ec6\u80de\u7684\u5185\u5316\uff0c\u5ef6\u957f\u5728\u8840\u6db2\u5faa\u73af\u4e2d\u7684\u6ede\u7559\u65f6\u95f4\uff0c\u5b9e\u73b0\u540c\u7c7b\u578b4T1\u4e73\u817a\u7ec6\u80de\u8f6c\u79fb\u6027\u764c\u75c7\u7684\u9776\u5411\u6cbb\u7597\uff0c\u6709\u52a9\u4e8e\u764c\u75c7\u4e2a\u4f53\u5316\u6cbb\u7597\u3002<\/p>\n

\u6587\u732e\u94fe\u63a5\uff1aCancer-Cell-Biomimetic Nanoparticles for Targeted Therapy of Homotypic Tumors<\/a>\uff08Adv. Mater., 2016, DOI: 10.1002\/adma.201602173\uff09<\/p>\n

2\u3001Nano Lett. \u5229\u7528\u8d85\u58f0\u6ce2\u5f15\u53d1\u5168\u6c1f\u78b3\u5316\u7269\u4ea7\u751f\u80bf\u7624\u6c27\u5316\u514b\u670d\u764c\u75c7\u6cbb\u7597\u4e2d\u7f3a\u6c27\u76f8\u5173\u6297\u529b<\/strong><\/p>\n

\"\u56fe\u72472\"<\/p>\n

\u56fe2 <\/strong>\u5168\u6c1f\u78b3\u5316\u7269(PFC)\u7eb3\u7c73\u4e73\u6db2\u7684\u5236\u5907\u548c\u6c27\u6c14\u7684\u91ca\u653e<\/strong><\/p>\n

\u82cf\u5dde\u5927\u5b66\u5218\u5e84\u6559\u6388\uff08\u901a\u8baf\u4f5c\u8005\uff09\u7b49\u4eba\u901a\u8fc7\u9759\u8109\u6ce8\u5c04\u5c06\u8840\u6e05\u767d\u86cb\u767d\u56fa\u5b9a\u7684\u5168\u6c1f\u78b3\u5316\u7269(PFC)\u7eb3\u7c73\u6db2\u6ef4\u6ce8\u5165\u8377\u7624\u5c0f\u9f20\uff0c\u5229\u7528PFC\u9ad8\u6eb6\u89e3\u6c27\u7684\u80fd\u529b\u8c03\u8282\u80bf\u7624\u7f3a\u6c27\u73af\u5883\u3002PFC\u7eb3\u7c73\u6db2\u6ef4\u5438\u9644\u80ba\u91cc\u7684\u6c27\u6c14\uff0c\u5728\u8d85\u58f0\u6ce2\u7684\u523a\u6fc0\u4e0b\u5728\u80bf\u7624\u4e2d\u5feb\u901f\u91ca\u653e\u6c27\u6c14\uff0c\u518d\u5faa\u73af\u56de\u80ba\u4e2d\u8fdb\u884c\u518d\u6c27\u5316\uff0c\u8fd9\u79cd\u5faa\u73af\u53ef\u589e\u5f3a\u80bf\u7624\u6c27\u5316\u5e76\u63d0\u9ad8PDT\u548cRT\u7684\u6cbb\u7597\u6548\u679c\u3002\u53ef\u514b\u670d\u80bf\u7624\u6cbb\u7597\u4e2d\u4ea7\u751f\u7684\u7f3a\u6c27\u76f8\u5173\u7684\u6297\u529b\u3002<\/p>\n

\u6587\u732e\u94fe\u63a5\uff1aUltrasound Triggered Tumor Oxygenation with Oxygen-Shuttle\u00a0Nanoperfluorocarbon to Overcome Hypoxia-Associated Resistance in Cancer Therapies<\/a>\uff08Nano Lett.,\u00a02016,\u00a0DOI: 10.1021\/acs.nanolett.6b02365\uff09<\/p>\n

3\u3001Adv. Mater. \u52a8\u6001\u63a7\u5236\u7684\u94f6\u7eb3\u7c73\u7ebf\u9635\u5217\u63a2\u6d4b\u57fa\u5e95\u8bf1\u5bfc\u7ec6\u80de\u62c9\u4f38\u751f\u957f\u7684\u5206\u5b50\u4fe1\u606f<\/strong><\/p>\n

\"\u56fe\u72473\"<\/p>\n

\u56fe3 <\/strong>\u6c7d\u5316\u8bf1\u5bfc\u7eb3\u7c73\u9897\u7c92\u7ec4\u88c5<\/p>\n

\u4e2d\u56fd\u79d1\u5b66\u9662\u5316\u5b66\u7814\u7a76\u6240\u7684\u738b\u94c1\u7814\u7a76\u5458\uff08\u901a\u8baf\u4f5c\u8005\uff09\u8bfe\u9898\u7ec4\u8fd1\u671f\u53d1\u5c55\u4e86\u4e00\u79cd\u5236\u5907\u9ad8\u5747\u4e00\u5ea6\u3001\u957f\u7a0b\u6709\u5e8f\u94f6\u7eb3\u7c73\u7ebf\u9635\u5217\u7684\u52a8\u6001\u63a7\u5236\u7b56\u7565\u3002\u8fd9\u4e00\u7b56\u7565\u4e3b\u8981\u6709\u4e24\u4e2a\u4f18\u52bf\uff1a\u4e00\u662f\u5229\u7528\u6db2\u76f8\u57fa\u8d28\u63d0\u9ad8\u94f6\u7eb3\u7c73\u7ebf\u60ac\u6d6e\u6db2\u7684\u8fc1\u79fb\u901f\u7387\uff08convection velocity\uff09\u4ece\u800c\u5b9e\u73b0\u77ed\u65f6\u6709\u5e8f\u7ec4\u88c5\uff1b\u4e8c\u662f\u5236\u5907\u7684\u5b9a\u5411\u94f6\u7eb3\u7c73\u7ebf\u9635\u5217\u662f\u5b9e\u73b0\u7ec6\u80de\u9ecf\u9644\u751f\u957f\u7684\u8868\u9762\u589e\u5f3a\u62c9\u66fc\u6563\u5c04\uff08SERS\uff09\u76d1\u6d4b\u7684\u7406\u60f3\u819c\u6750\u6599\u3002\u6b64\u5916\uff0c\u7531\u4e8e\u5176\u81ea\u8eab\u4f18\u5f02\u7684\u5bfc\u70ed\u5bfc\u7535\u6027\u80fd\uff0c\u8fd9\u4e00\u5b9a\u5411\u94f6\u7eb3\u7c73\u7ebf\u6750\u6599\u4e3a\u5b9e\u73b0\u7535\u3001\u70ed\u523a\u6fc0\u4e0b\u7684\u795e\u7ecf\u6216\u7ec4\u7ec7\u884c\u4e3a\u7814\u7a76\u63d0\u4f9b\u4e86\u53ef\u80fd\u3002<\/p>\n

\u6587\u732e\u94fe\u63a5\uff1aDynamically Regulated Ag Nanowire Arrays for Detecting Molecular Information of Substrate-Induced Stretched Cell Growth<\/a>\uff08Adv. Mater., 2016, DOI: 10.1002\/adma.201603223\uff09<\/p>\n

4\u3001Nano lett. \u78c1\u529b\u9a71\u52a8\u86cb\u767d\u9176\u4f20\u611f\u5668\u7528\u4e8e\u4f53\u5185\u80bf\u7624\u5206\u6790<\/strong><\/p>\n

\"\u56fe\u72474\"<\/p>\n

\u56fe4 <\/strong>\u78c1\u529b\u9a71\u52a8\u86cb\u767d\u9176\u751f\u7269\u4f20\u611f\u5668<\/p>\n

\u9ebb\u7701\u7406\u5de5\u5b66\u9662\u7684P. Anikeeva\u548cS. N. Bhatia\u7b49\u4eba\u8bbe\u8ba1\u4e86\u4e00\u79cd\u53ef\u4ee5\u68c0\u6d4b\u86cb\u767d\u9176\u6d3b\u6027\u5e76\u4e14\u53ef\u4ee5\u8fdc\u7a0b\u6d3b\u5316\u7684\u751f\u7269\u4f20\u611f\u5668\u3002\u8fd9\u79cd\u7eb3\u7c73\u4f20\u611f\u5668\u7531\u70ed\u654f\u6027\u7684\u8102\u8d28\u4f53\u7ec4\u6210\uff0c\u8102\u8d28\u4f53\u5185\u5305\u88f9\u6709\u7ecf\u8fc7\u529f\u80fd\u5316\u5904\u7406\u7684\u86cb\u767d\u9176\u5e95\u7269\u4e0e\u78c1\u6027\u7eb3\u7c73\u9897\u7c92\u3002\u5728\u764c\u75c7\u75c5\u53d8\u4f4d\u70b9\u5916\u52a0\u4ea4\u53d8\u78c1\u573a\u7684\u4f5c\u7528\u4e0b\uff0c\u78c1\u6027\u7eb3\u7c73\u9897\u7c92\u7531\u4e8e\u78c1\u6ede\u635f\u8017\u5c06\u70ed\u80fd\u4f20\u9012\u5230\u8102\u8d28\u5c42\uff0c\u8102\u8d28\u5c42\u53d7\u70ed\u5206\u89e3\u91ca\u653e\u591a\u80bd\u5e95\u7269\u3002\u901a\u8fc7\u5c3f\u6db2\u53ef\u4ee5\u5b9a\u91cf\u5206\u6790\u76f8\u5e94\u86cb\u767d\u9176\u88c2\u89e3\u76ee\u6807\u591a\u80bd\u7a0b\u5ea6\uff0c\u4ece\u800c\u68c0\u6d4b\u86cb\u767d\u9176\u6d3b\u6027\u3002\u8fd9\u79cd\u6750\u6599\u8fd8\u53ef\u4ee5\u7ed3\u5408\u78c1\u5171\u632f\u9020\u5f71\u8fdb\u884c\u764c\u75c7\u7684\u591a\u6a21\u5f0f\u8bca\u7597\u3002<\/p>\n

\u6587\u732e\u94fe\u63a5\uff1aMagnetically Actuated Protease Sensors for in Vivo Tumor Profiling<\/a>\uff08Nano lett., 2016, DOI: 10.1021\/acs.nanolett.6b02670\uff09<\/p>\n

5\u3001Nat. Commun. \u7535\u5149\u5b50\u7845\u751f\u7269\u4f20\u611f\u5668<\/strong><\/p>\n

\"\u56fe\u72475\"<\/p>\n

\u56fe5 <\/strong>\u7535\u5149\u73af\u5f62\u8154<\/p>\n

\u82f1\u56fd\u7ea6\u514b\u5927\u5b66J. J. -Cola\u00b4s\u548cA. Parkin\u7b49\u4eba\u53d1\u8868\u6587\u7ae0\u62a5\u9053\u4e86\u4e00\u79cd\u53ef\u4ee5\u5bf9\u751f\u7269\u6807\u5fd7\u7269\u8fdb\u884c\u9ad8\u7075\u654f\u5ea6\u548c\u591a\u53c2\u6570\u5206\u6790\u7684\u7535\u5316\u5b66\u7845\u5149\u5b50\u4f20\u611f\u5668\u3002\u5229\u7528\u7535\u5316\u5b66\u63a7\u5236\uff0c\u7814\u7a76\u4eba\u5458\u5b9e\u73b0\u4e86\u5bf9\u4e0d\u540c\u751f\u7269\u5206\u5b50\u5728\u4f20\u611f\u5668\u9635\u5217\u5355\u5fae\u73af\u4e0a\u7684\u4f4d\u70b9\u7279\u5f02\u6027\u56fa\u5b9a\uff0c\u518d\u901a\u8fc7\u5149\u5b50\u548c\u7535\u5316\u5b66\u8868\u5f81\u6280\u672f\u7684\u7ed3\u5408\u53ef\u4ee5\u83b7\u5f97\u72ec\u4e00\u65e0\u4e8c\u7684\u5b9a\u91cf\u4fe1\u606f\u548c\u5316\u5b66\u53cd\u5e94\u4fe1\u606f\u3002\u901a\u8fc7\u5bf9\u5149\u7535\u6027\u8d28\u7684\u5f00\u53d1\uff0c\u7845\u4f20\u611f\u5668\u4e3a\u5fae\u5c3a\u5ea6\u611f\u6d4b\u521b\u9020\u4e86\u65b0\u7684\u6a21\u5f0f\u3002<\/p>\n

\u6587\u732e\u94fe\u63a5\uff1aThe electrophotonic silicon biosensor<\/a>\uff08Nat. Commun., 2016, DOI: 10.1038\/ncomms12769\uff09<\/p>\n

6\u3001Nat. Nanotech. \u5728\u5bc6\u96c6\u7fa4\u4e2d\u5b9e\u73b0\u5355\u4e2a\u751f\u7269\u5206\u5b50\u7684\u5149\u5b66\u6210\u50cf<\/strong><\/p>\n

\"\u56fe\u72476\"<\/p>\n

\u56fe6 <\/strong>\u8d85\u5206\u8fa8\u7387DMI(\u79bb\u6563\u5206\u5b50\u6210\u50cf)\u6982\u5ff5\u793a\u610f\u56fe<\/p>\n

\u7f8e\u56fd\u54c8\u4f5b\u5927\u5b66Peng Yin\u7b49\u4eba\u5229\u7528DNA-PAINT(\u7eb3\u7c73\u5c3a\u5ea6\u70b9\u79ef\u7d2f\u6210\u50cf)\u5b9e\u73b0\u5bf9\u5355\u4e2a\u751f\u7269\u5206\u5b50\u7684\u76f4\u63a5\u5149\u5b66\u89c2\u5bdf\u3002\u5229\u7528\u8fd9\u79cd\u8d85\u5206\u8fa8\u7387\u8367\u5149\u663e\u5fae\u6280\u672f\u5f97\u5230\u4e00\u79cd\u504f\u79fb\u4fee\u6b63\u65b9\u6cd5\uff0c\u53ef\u4ee5\u5206\u6790DNA\u6298\u7eb8\u7ed3\u6784\u5728<2 \u00c5\u7cbe\u5ea6\u8303\u56f4\u7684\u504f\u79fb\u3002\u8fd9\u79cdDMI\u6280\u672f\u65e8\u5728\u5bf9\u5206\u5b50\u7ec4\u4ef6\u5b9e\u73b0\u79bb\u6563\u7684\u53ef\u89c6\u5316\uff0c\u5728\u590d\u6742\u751f\u7269\u6216\u5408\u6210\u7eb3\u7c73\u7ea7\u7cfb\u7edf\u4e2d\u51c6\u786e\u5b9a\u4f4d\u5206\u5b50\u7ec4\u4ef6\uff0c\u5177\u6709\u826f\u597d\u7684\u5355\u5206\u5b50\u654f\u611f\u6027\u548c\u76ee\u6807\u5206\u8fa8\u80fd\u529b\u3002<\/p>\n

\u6587\u732e\u94fe\u63a5\uff1aOptical imaging of individual biomolecules in densely packed clusters<\/a>\uff08Nat. Nanotech.,\u00a02016,\u00a0DOI: 10.1038\/nnano.2016.95\uff09<\/p>\n

7\u3001Nat. Nanotech. \u5b58\u5728\u4e8e\u8102\u591a\u7cd6\u4e2d\u7684\u91d1\u5c5e\u7eb3\u7c73\u9897\u7c92\u5f15\u53d1\u5c0f\u9f20\u7684\u91d1\u5c5e\u8fc7\u654f<\/strong><\/p>\n

\"\u56fe\u72477\"<\/p>\n

\u56fe7 <\/strong>\u4e0d\u540c\u7eb3\u7c73\u94f6\u7c92\u5b50\u81f4\u654f\u4f5c\u7528\uff08\u9020\u6210\u8033\u6c34\u80bf\u7a0b\u5ea6\uff09\u793a\u610f\u56fe<\/p>\n

\u65e5\u672c\u5927\u962a\u5927\u5b66Yasuo Yoshioka\uff08\u901a\u8baf\u4f5c\u8005\uff09\u548cYasuo Tsutsumi\uff08\u901a\u8baf\u4f5c\u8005\uff09\u7b49\u4eba\u4f7f\u7528\u7eb3\u7c73\u94f6\u7c92\u5b50(nAg)\u548c\u8102\u591a\u7cd6\u5904\u7406\u5c0f\u9f20\uff0c\u7814\u7a76nAg\u5f15\u8d77\u7684\u514d\u75ab\u53cd\u5e94\u3002\u7814\u7a76\u53d1\u73b0\u5c0f\u5c3a\u5bf8\u7684nAg(\u226410nm)\u4f1a\u8f6c\u79fb\u5230\u6dcb\u5df4\u7ed3\u4e2d\uff0c\u76f8\u6bd4\u5927\u5c3a\u5bf8\u7684nAg(>10nm)\u66f4\u6613\u91ca\u653e\u94f6\u79bb\u5b50\uff0c\u8bf1\u53d1\u5c0f\u9f20\u7684\u514d\u75ab\u53cd\u5e94\u3002\u540c\u6837\uff0c\u954d\u7eb3\u7c73\u7c92\u5b50\u4e5f\u4f1a\u5bf9\u5c0f\u9f20\u4ea7\u751f\u81f4\u654f\u4f5c\u7528\u3002\u7814\u7a76\u8bc1\u5b9e\u4e86\u91d1\u5c5e\u7eb3\u7c73\u7c92\u5b50\u4f5c\u4e3a\u79bb\u5b50\u8f7d\u4f53\u4f1a\u4ea7\u751f\u91d1\u5c5e\u81f4\u654f\uff0c\u662f\u4e00\u79cd\u6f5c\u5728\u5f15\u53d1\u91d1\u5c5e\u81f4\u654f\u7684\u65b0\u7684\u81f4\u654f\u7269\u8d28\u3002<\/p>\n

\u6587\u732e\u94fe\u63a5\uff1aMetal nanoparticles in the presence of lipopolysaccharides trigger the onset of metal allergy in mice<\/a>\uff08Nat. Nanotech.,\u00a02016,\u00a0DOI: 10.1038\/nnano.2016.88\uff09<\/p>\n

8\u3001PNAS\uff1a\u529f\u80fd\u6027\u805a\u916f\u9009\u62e9\u6027\u5730\u8d8a\u8fc7\u5339\u914d\u7684\u6b63\u5e38\u7ec6\u80de\u8fd0\u8f7dsiRNA\u81f3\u80ba\u764c\u7ec6\u80de<\/strong><\/p>\n

\"\u56fe\u72478\"<\/p>\n

\u56fe8 <\/strong>\u529f\u80fd\u6027\u805a\u916f\u7eb3\u7c73\u9897\u7c92\u7684\u7b5b\u9009\u53ca\u9009\u62e9\u6027\u5730\u8fd0\u8f7dsiRNA\u81f3\u80ba\u764c\u7ec6\u80de<\/p>\n

\u6700\u8fd1\u7f8e\u56fd\u5fb7\u514b\u8428\u65af\u5927\u5b66\u897f\u5357\u533b\u5b66\u4e2d\u5fc3Daniel J. Siegwart\uff08\u901a\u8baf\u4f5c\u8005\uff09\u62a5\u9053\u4e00\u79cd\u529f\u80fd\u6027\u805a\u916f\u80fd\u9009\u62e9\u6027\u5730\u8d8a\u8fc7\u5339\u914d\u7684\u6b63\u5e38\u7ec6\u80de\u800c\u8fd0\u8f7dsiRNA\u836f\u7269\u81f3\u80ba\u764c\u7ec6\u80de\uff0c\u4e14\u65e0\u9700\u4efb\u4f55\u9776\u5411\u914d\u4f53\u3002\u529f\u80fd\u6027\u805a\u916f\u662f\u4ece\u7ec4\u5408\u6587\u5e93\u4e2d\u901a\u8fc7\u9ad8\u901a\u91cf\u7b5b\u9009\u60a3\u8005\u7684\u764c\u75c7\u7ec6\u80de\u548c\u6b63\u5e38\u7ec6\u80de\u7cfb\u5bf9\u83b7\u5f97\u7684\u3002\u5c06\u5176\u6ce8\u5165\u5c0f\u9f20\u7684\u79fb\u690d\u7624\u4e2d\uff0c\u53d1\u73b0\u8fd9\u79cd\u9009\u62e9\u6027\u7eb3\u7c73\u9897\u7c92\u5728\u80bf\u7624\u90e8\u4f4d\u80fd\u6ede\u7559\u4e00\u5468\u4ee5\u4e0a\uff0c\u800c\u975e\u9009\u62e9\u6027\u7eb3\u7c73\u9897\u7c92\u51e0\u4e2a\u5c0f\u65f6\u5185\u5c31\u88ab\u6e05\u9664\u3002\u8fd9\u79cd\u9009\u62e9\u6027\u9897\u7c92\u80fd\u5728\u79fb\u690d\u7624\u548c\u539f\u4f4d\u7624\u4e2d\u4ecb\u5bfc\u57fa\u56e0\u6c89\u9ed8\uff0c\u5b9e\u73b0\u6cbb\u7597\u764c\u75c7\u7684\u76ee\u7684\uff0c\u5c06\u6709\u52a9\u4e8e\u764c\u75c7\u4e2a\u4f53\u5316\u6cbb\u7597\u3002<\/p>\n

\u6587\u732e\u94fe\u63a5\uff1aFunctional polyesters enable selective siRNA delivery to lung cancer over matched normal cells <\/a>( PNAS, 2016, DOI: 10.1073\/pnas.1606886113)<\/p>\n

9\u3001Adv. Mater. \u5229\u7528\u4e9a\u80fa\u57fa\u5171\u4ef7\u6709\u673a\u9aa8\u67b6\u7684\u975e\u5171\u4ef7\u76f8\u4e92\u4f5c\u7528\u8fdb\u884c\u69f2\u76ae\u7d20\u8f93\u9001<\/strong><\/p>\n

\"\u56fe\u72479\"<\/p>\n

\u56fe9 <\/strong>\u4e9a\u80fa\u57fa\u5171\u4ef7\u6709\u673a\u9aa8\u67b6\u7528\u4e8e\u69f2\u76ae\u7d20\u8f93\u9001<\/p>\n

\u5171\u4ef7\u6709\u673a\u9aa8\u67b6\uff08COFs\uff09\u662f\u4e00\u79cd\u5177\u6709\u9ad8\u88c5\u8f7d\u5bb9\u91cf\u548c\u826f\u597d\u751f\u7269\u76f8\u5bb9\u6027\u7684\u7eb3\u7c73\u591a\u5b54\u805a\u5408\u7269\u836f\u7269\u8f93\u9001\u8f7d\u4f53\u3002\u5fb7\u56fd\u9a6c\u514b\u601d\u666e\u6717\u514b\u56fa\u4f53\u7814\u7a76\u6240\u7684Bettina V. Lotsch\uff08\u901a\u8baf\u4f5c\u8005\uff09\u7b49\u4eba\u901a\u8fc7\u6c22\u952e\u5728\u5206\u5b50\u6c34\u5e73\u4e0a\u5bf9\u8f7d\u4f53\u548c\u8f93\u9001\u836f\u7269\u4e4b\u95f4\u7684\u76f8\u4e92\u4f5c\u7528\u8fdb\u884c\u4e86\u8c03\u63a7\u3002\u7ec6\u80de\u589e\u6b96\u7814\u7a76\u8868\u660e\u91c7\u7528COF\u4f5c\u4e3a\u7eb3\u7c73\u8f93\u9001\u8f7d\u4f53\uff0c\u836f\u7269\u5728\u80bf\u7624\u7ec6\u80de\u4e2d\u5177\u6709\u66f4\u9ad8\u7684\u8f93\u9001\u6548\u7387\u3002<\/p>\n

\u6587\u732e\u94fe\u63a5\uff1aExploiting Noncovalent Interactions in an Imine-Based Covalent Organic Framework for Quercetin Delivery<\/a> (Adv. Mater., 2016, DOI: 10.1002\/adma.201603006\uff09<\/p>\n

10\u3001PNAS\uff1a\u4e8c\u7532\u53cc\u80cd\u548c\u7eb3\u7c73\u9897\u7c92\u7ed3\u5408\u9776\u5411\u6cbb\u7597\u80f0\u817a\u764c<\/strong><\/p>\n

\"\u56fe\u724710\"<\/p>\n

\u56fe10 <\/strong>BPTES-NPs\u4f7f\u5c0f\u9f20\u7684\u80f0\u817a\u80bf\u7624\u5177\u6709\u8f83\u9ad8\u7684\u836f\u7269\u6d53\u5ea6<\/p>\n

\u7ea6\u7ff0\u970d\u666e\u91d1\u65af\u5927\u5b66\u533b\u5b66\u9662\u7684Gregg L. Semenza\u3001Justin Hanes\u3001Barbara S. Slusher\u548cAnne Le\uff08\u5171\u540c\u901a\u8baf\u4f5c\u8005\uff09\u7b49\u4eba\u7814\u7a76\u53d1\u73b0\u591a\u79cd\u6297\u764c\u836f\u7269\u7ec4\u5408\u7684\u6cbb\u7597\u6548\u679c\u597d\u4e8e\u5355\u79cd\u836f\u7269\u6cbb\u7597\u3002\u4ed6\u4eec\u5c06\u4e00\u79cd\u53eb\u505aBPTES\u7684\u8bd5\u9a8c\u6027\u836f\u7269\u5305\u88c5\u5230\u7531\u805a\u4e59\u4e8c\u9187\u5305\u88ab\u7684\u7eb3\u7c73\u9897\u7c92\u80f6\u56ca\u4e2d\uff0c\u8fd9\u79cd\u7eb3\u7c73\u9897\u7c92\u80fd\u591f\u5e2e\u52a9\u836f\u7269\u7a7f\u8fc7\u9760\u8fd1\u764c\u7ec6\u80de\u7684\u6bdb\u7ec6\u8840\u7ba1\uff0c\u4f7f\u836f\u7269\u5728\u80bf\u7624\u7ec4\u7ec7\u4e2d\u7684\u505c\u7559\u65f6\u95f4\u66f4\u957f\u3002\u7136\u540e\u5c06\u6297\u7cd6\u5c3f\u75c5\u836f\u7269\u4e8c\u7532\u53cc\u80cd\u4e0e\u80f6\u56ca\u5316\u7684BPTES\u8054\u5408\u4f7f\u7528\uff0c\u7528\u4ee5\u6cbb\u7597\u79fb\u690d\u4e86\u4eba\u7c7b\u80f0\u817a\u80bf\u7624\u7684\u5c0f\u9f20\uff0c\u7ed3\u679c\u8868\u660e\u836f\u7269\u7ec4\u5408\u4f7f\u80bf\u7624\u7f29\u5c0f\u4e86\u81f3\u5c1150%\uff0c\u6548\u679c\u597d\u4e8e\u5355\u79cd\u836f\u7269\u6cbb\u7597\u3002<\/p>\n

\u6587\u732e\u94fe\u63a5\uff1aCombination therapy with BPTES nanoparticles and metformin targets the metabolic heterogeneity of pancreatic cancer<\/a> (PNAS, 2016, DOI: 10.1073\/pnas.1611406113\uff09<\/p>\n

11\u3001Angew. Chem. Int. Ed. \u5177\u6709\u9009\u62e9\u6e17\u900f\u6027\u7684\u4eff\u751f\u590d\u5408\u7eb3\u7c73\u5bb9\u5668<\/strong><\/p>\n

\"\u56fe\u724711\"<\/p>\n

\u56fe11 <\/strong>\u7531\u4e24\u4eb2\u6027\u5d4c\u6bb5\u5171\u805a\u7269\u548cDNA\u7eb3\u7c73\u5b54\u7ec4\u6210\u7684\u529f\u80fd\u590d\u5408\u7eb3\u7c73\u5bb9\u5668<\/p>\n

\u82f1\u56fd\u4f26\u6566\u5927\u5b66\u5b66\u9662\u7684Giuseppe Battaglia\u548cStefan Howorka\uff08\u5171\u540c\u901a\u8baf\u4f5c\u8005\uff09\u7b49\u4eba\u5c06\u4e24\u4eb2\u6027\u5d4c\u6bb5\u5171\u805a\u7269\u548c\u8584\u819c\u72b6DNA\u7eb3\u7c73\u5b54\u590d\u5408\uff0c\u5f62\u6210\u4e86\u4e00\u79cd\u529f\u80fd\u6027\u4eff\u751f\u590d\u5408\u7eb3\u7c73\u5bb9\u5668\u3002\u8be5\u805a\u5408\u7269\u56ca\u6ce1\u548cDNA\u7eb3\u7c73\u5b54\u7684\u9ad8\u5ea6\u53ef\u8c03\u63a7\u6027\u5c06\u6210\u4e3a\u7eb3\u7c73\u5bb9\u5668\u7528\u4e8e\u836f\u7269\u8f93\u9001\u3001\u751f\u7269\u6210\u50cf\u3001\u751f\u7269\u50ac\u5316\u548c\u7ec6\u80de\u6a21\u62df\u7b49\u5e94\u7528\u7684\u5173\u952e\u3002<\/p>\n

\u6587\u732e\u94fe\u63a5\uff1aBiomimetic Hybrid Nanocontainers with Selective Permeability<\/a> (Angew. Chem. Int. Ed., 2016, DOI: 10.1002\/anie.201604677\uff09<\/p>\n

12\u3001Nat. Commun. \u8fc7\u6e21\u91d1\u5c5e\u5143\u7d20\u5728\u6d3b\u7ec6\u80de\u7ebf\u7c92\u4f53\u4e2d\u7684\u50ac\u5316\u4f5c\u7528<\/strong><\/p>\n

\"\u56fe\u724712\"<\/p>\n

\u56fe12 <\/strong>(a) \u70ef\u4e19\u57fa\u8fc7\u6e21\u91d1\u5c5e\u5143\u7d20\u5316\u5408\u7269\uff1b(b) \u9776\u5411\u5242\u4f5c\u7528\u4e0b\u91d1\u5c5e\u50ac\u5316\u5242\u5728\u7ec6\u80de\u7ebf\u7c92\u4f53\u7684\u4f18\u5148\u5bcc\u96c6<\/p>\n

\u897f\u73ed\u7259\u5723\u5730\u4e9a\u54e5\u5fb7\u5b54\u6ce2\u65af\u7279\u62c9\u5927\u5b66\u6709\u673a\u5316\u5b66\u7cfb\u7684\u7684Jos\u00e9 L. Mascare\u0144as\uff08\u901a\u8baf\u4f5c\u8005\uff09\u7b49\u4eba\u8bbe\u8ba1\u4e86\u4e00\u79cd\u8fc7\u6e21\u91d1\u5c5e\u948c\u914d\u5408\u7269\uff0c\u5b83\u53ef\u4ee5\u4f18\u5148\u7684\u5728\u54fa\u4e73\u52a8\u7269\u7684\u7ec6\u80de\u7ebf\u7c92\u4f53\u4e2d\u79ef\u7d2f\uff0c\u5e76\u80fd\u5177\u6709\u548c\u5728\u5916\u754c\u4e00\u6837\u53cd\u5e94\u80fd\u529b\u3002\u66f4\u91cd\u8981\u7684\u662f\uff0c\u8fd9\u79cd\u5728\u7ec6\u80de\u7ebf\u7c92\u4f53\u4e2d\u7684\u6d3b\u6027\u53ef\u4ee5\u7528\u6765\u9650\u5236\u8367\u5149\u7684\u53d1\u5c04\uff0c\u901a\u8fc7\u524d\u4f53\u7ec6\u80de\u7684\u5c40\u90e8\u7684\u8f6c\u53d8\u53ef\u4ee5\u5b9e\u73b0\u9009\u62e9\u6027\u7684\u529f\u80fd\u5316\u8f6c\u53d8\u3002<\/p>\n

\u6587\u732e\u94fe\u63a5\uff1a Cancer-Cell-Biomimetic Nanoparticles for Targeted Therapy of Homotypic Tumors<\/a>(Nat. Commun., 2016, DOI:10.1038\/ncomms12538)<\/p>\n

\u672c\u6587\u7531\u6750\u6599\u4eba\u751f\u7269\u6750\u6599\u5b66\u4e60\u5c0f\u7ec4\u4f9b\u7a3f\uff0c\u6750\u6599\u725b\u7f16\u8f91\u6574\u7406\u3002<\/p>\n

\u6b22\u8fce\u52a0\u5165\u6750\u6599\u4eba\u751f\u7269\u6750\u6599\u5b66\u4e60\u5c0f\u7ec4\uff0c\u4e00\u8d77\u63a2\u8ba8\u751f\u7269\u6750\u6599\u7684\u4e13\u4e1a\u95ee\u9898\uff0c\u5173\u6ce8\u751f\u7269\u6750\u6599\u7684\u6700\u65b0\u52a8\u6001\u3002\u52a0\u5165\u65b9\u5f0f\uff1a\uff081\uff09\u6dfb\u52a0\u6750\u6599\u4eba\u751f\u7269\u6750\u6599\u4ea4\u6d41\u7fa4\uff08124806506\uff09\uff0c\u79c1\u4fe1\u7ba1\u7406\u5458\u201c\u9648\u662d\u94ed\uff08QQ\uff1a1982342885\uff09\u201d\u62a5\u540d\uff1b\uff082\uff09\u70b9\u6b64\u5904\u62a5\u540d<\/a>\u3002<\/p>\n

\u6750\u6599\u4eba\u7f51\u5c0a\u91cd\u6240\u6709\u8fdb\u884c\u77e5\u8bc6\u4f20\u64ad\u7684\u5a92\u4f53\uff0c\u8f6c\u8f7d\u8bf7\u8054\u7cfbtougao@cailiaoren.com<\/p>\n","protected":false},"excerpt":{"rendered":"

1\u3001Adv. Mater. \u751f\u7269\u6a21\u62df\u764c\u7ec6\u80de\u7684\u7eb3\u7c73\u9897\u7c92\u5b9e\u73b0\u540c\u7c7b\u578b\u764c\u7ec6\u80de\u7684\u9776\u5411\u6cbb\u7597 \u56fe1 \u751f\u7269\u6a21\u62df\u764c\u7ec6\u80de\u7684\u7eb3\u7c73\u9897\u7c92\u5b9e\u73b0\u540c\u7c7b\u578b\u764c\u7ec6\u80de\u7684\u9776\u5411\u6cbb\u7597\u7684\u793a\u610f\u56fe \u6700\u8fd1\uff0c\u4e2d\u56fd\u79d1\u5b66…<\/p>\n","protected":false},"author":382,"featured_media":43081,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[67],"tags":[75],"class_list":["post-43079","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-zhoubao","tag-biomaterial"],"_links":{"self":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts\/43079"}],"collection":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/users\/382"}],"replies":[{"embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=43079"}],"version-history":[{"count":5,"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts\/43079\/revisions"}],"predecessor-version":[{"id":44521,"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts\/43079\/revisions\/44521"}],"wp:featuredmedia":[{"embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/media\/43081"}],"wp:attachment":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=43079"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=43079"},{"taxonomy":"post_tag","embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=43079"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}