{"id":36319,"date":"2016-09-17T14:00:36","date_gmt":"2016-09-17T06:00:36","guid":{"rendered":"\/\/m.iemloyee.com\/?p=36319"},"modified":"2017-03-18T21:35:07","modified_gmt":"2017-03-18T13:35:07","slug":"%e5%86%b2%e5%87%bb%e5%b8%82%e5%9c%ba%e7%9a%84%e7%be%8e%e5%ae%b9%e6%8a%80%e6%9c%af%e4%b8%a8%e7%ac%ac%e4%ba%8c%e5%b1%82%e8%82%8c%e8%82%a4%ef%bc%8d%e5%8f%af%e7%a9%bf","status":"publish","type":"post","link":"\/\/m.iemloyee.com\/?p=36319","title":{"rendered":"\u51b2\u51fb\u5e02\u573a\u7684\u201c\u7f8e\u5bb9\u6280\u672f\u201d\u4e28\u201c\u7b2c\u4e8c\u5c42\u808c\u80a4\u201d\uff0d\u53ef\u7a7f\u6234\u5f0f\u9ad8\u5206\u5b50\u805a\u5408\u7269\uff1a\u76ae\u80a4\u66ff\u4ee3\u7269"},"content":{"rendered":"<p>\u76ae\u80a4\u7684\u4e3b\u8981\u4f5c\u7528\u662f\u7ed9\u4eba\u4f53\u7684\u5185\u90e8\u751f\u7406\u73af\u5883\u63d0\u4f9b\u4fdd\u62a4\u5c4f\u969c\uff0c\u907f\u514d\u66b4\u9732\u5728\u6076\u52a3\u73af\u5883\u4e0b\uff08\u5c24\u5176\u662f\u8f90\u5c04\uff0c\u5fae\u751f\u7269\uff0c\u9ad8\u6e29\uff0c\u6bd2\u7d20\u4ee5\u53ca\u673a\u68b0\u635f\u4f24\uff09\u3002\u540c\u65f6\uff0c\u76ae\u80a4\u7684\u7f8e\u5b66\u610f\u4e49\u4e5f\u662f\u6bcb\u5eb8\u7f6e\u7591\u7684\uff1a\u5b83\u51b3\u5b9a\u4e86\u4e00\u4e2a\u4eba\u7684\u7b2c\u4e00\u5370\u8c61\uff0c\u5728\u5fc3\u7406\u5c42\u9762\u4e0a\u5f71\u54cd\u81ea\u4fe1\u5fc3\u3002\u5728\u8fd9\u4e2a\u989c\u503c\u5f53\u9053\u3001\u201c\u9c9c\u8089\u201d\u6a2a\u884c\u7684\u65f6\u4ee3\uff0c\u76ae\u80a4\u8870\u8001\u65e0\u7591\u662f\u592a\u591a\u4eba\u6297\u4e89\u7684\u5bf9\u8c61\uff0c\u5373\u4f7f\u8fd9\u662f\u751f\u7269\u8fdb\u5316\u548c\u57fa\u56e0\u8868\u8fbe\u6240\u51b3\u5b9a\u7684\u4e0d\u4e89\u4e8b\u5b9e\u3002\u5e74\u8f7b\u7684\u76ae\u80a4\u6bd4\u8870\u8001\u7684\u8981\u539a\u5b9e\uff0c\u76ae\u80a4\u8868\u5c42\u80fd\u591f\u6563\u5c04\u5149\u7ebf\u800c\u5448\u73b0\u5982\u51dd\u8102\u822c\u7684\u5149\u6cfd\u3002\u5b83\u4eec\u7684\u533a\u522b\u540c\u6837\u5b58\u5728\u4e8e\u76ae\u80a4\u7684\u771f\u76ae\u5c42\u3002\u771f\u76ae\u5c42\u5b58\u5728\u7740\u5927\u91cf\u7684\u80f6\u539f\u548c\u5f39\u6027\u86cb\u767d\uff0c\u8fd9\u4e9b\u80f6\u539f\u548c\u5f39\u6027\u86cb\u767d\u8d4b\u4e88\u4e86\u808c\u80a4\u5f39\u6027\u548c\u7d27\u81f4\u611f\u3002\u7136\u800c\u5ea6\u8fc7\u9752\u6625\u671f\u7684\u6211\u4eec\u4ee51.5%\u7684\u901f\u5ea6\u5931\u53bb\u76ae\u80a4\u4e2d\u7684\u80f6\u539f\u86cb\u767d\uff0c\u7d2b\u5916\u7ebf\u4f24\u5bb3\u548c\u5438\u70df\u4e5f\u4f1a\u52a0\u901f\u8fd9\u4e00\u8fc7\u7a0b\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-36322\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2016\/08\/1-29.png\" alt=\"1\" width=\"520\" height=\"324\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2016\/08\/1-29.png 520w, \/\/m.iemloyee.com\/wp-content\/uploads\/2016\/08\/1-29-300x187.png 300w\" sizes=\"(max-width: 520px) 100vw, 520px\" \/><\/p>\n<p style=\"text-align: center;\"><strong>\u56fe1 <\/strong>\u80e1\u6b4c\u6b27\u5df4\u7684\u5267\u7167 (from baidu \u56fe\u7247\uff0cPS: \u5373\u4f7f\u7528\u7bad\u5934\u6807\u51fa\u4ed6\u7684\u75a4\u75d5\uff0c\u4f46\u4f5c\u8005\u975e\u5e38\u6b23\u8d4f\u4ed6\u52ab\u540e\u4f59\u751f\u7684\u98de\u8dc3)<\/p>\n<p>\u6240\u8c13\u9053\u9ad8\u4e00\u5c3a\uff0c\u9b54\u9ad8\u4e00\u4e08\u3002\u4e00\u65b9\u9762\u6211\u4eec\u7528\u60f3\u50cf\u53bb\u7be1\u6539\u8fd9\u4e2a\u4e0d\u592a\u6109\u5feb\u7684\u81ea\u7136\u8fc7\u7a0b\uff1a\u7a7f\u8d8a\u5267\u4e2d\u5973\u4e3b\u91cd\u8fd4\u4e8c\u516b\u5e74\u534e\uff0c\u91cd\u83b7\u5439\u5f39\u53ef\u7834\u3001\u80f6\u539f\u86cb\u767d\u7206\u68da\u7684\u808c\u80a4\uff1b\u300a\u7405\u740a\u699c\u300b\u4e2d\u610f\u6deb\u80e1\u6b4c\u6b27\u5df4\uff0c\u906d\u53d7\u706b\u5bd2\u4e4b\u6bd2\u540e\u6413\u9aa8\u78e8\u76ae\uff0c\u7528\u53e6\u4e00\u4ed8\u76ae\u56ca\u793a\u4eba \uff08\u56fe1\uff09\u3002\u53e6\u4e00\u65b9\u9762\uff0c\u5728\u8fd9\u4e9b\u7f8e\u597d\u613f\u671b\u7684\u9a71\u4f7f\u4e0b\uff0c\u5ef6\u7f13\u4ee5\u53ca\u6d88\u9664\u76ae\u80a4\u8870\u8001\u6210\u4e3a\u7099\u624b\u53ef\u70ed\u5374\u5145\u6ee1\u6311\u6218\u7684\u7814\u7a76\u8bfe\u9898\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-36323\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2016\/08\/2-29.png\" alt=\"2\" width=\"462\" height=\"270\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2016\/08\/2-29.png 462w, \/\/m.iemloyee.com\/wp-content\/uploads\/2016\/08\/2-29-300x175.png 300w\" sizes=\"(max-width: 462px) 100vw, 462px\" \/><\/p>\n<p style=\"text-align: center;\"><strong>\u56fe2 <\/strong>\u6ce8\u5c04\u73bb\u5c3f\u9178\u586b\u5145\u7269<\/p>\n<p>\u73bb\u5c3f\u9178 (hyaluronic acid)\u53ef\u8c13\u662f\u9ad8\u9891\u8bcd\u6c47\uff0c\u9891\u7e41\u51fa\u73b0\u5728\u5404\u5927\u5a31\u4e50\u7248\u9762\u3002\u5f53\u5927\u4f17\u770b\u5230\u4e00\u5f20\u5f20\u6ee1\u5c4f\u80f6\u539f\u86cb\u767d\u5374\u76ae\u7b11\u8089\u4e0d\u7b11\u7684\u86c7\u7cbe\u8138\u65f6\uff0c\u73bb\u5c3f\u9178\u4fbf\u65e0\u4e00\u4f8b\u5916\u5730\u6210\u4e3a\u4e86\u59cb\u4f5c\u4fd1\u8005\u3002\u73bb\u5c3f\u9178\u5e76\u4e0d\u795e\u79d8\uff0c\u5b83\u662f\u4e00\u79cd\u8d1f\u7535\u8377\u7684\u975e\u786b\u5316\u7684\u7c98\u591a\u7cd6\uff0c\u5e7f\u6cdb\u5730\u5b58\u5728\u4e8e\u8f6f\u9aa8\u7b49\u7ed3\u7f14\u7ec4\u7ec7\u4e2d\u3002\u6b63\u56e0\u4e3a\u5e26\u8d1f\u7535\u8377\uff0c\u5b83\u80fd\u591f\u5438\u6c34\u5e76\u5728\u5438\u6c34\u5931\u6c34\u7684\u8fc7\u7a0b\u4e2d\u8d4b\u4e88\u7ed3\u7f14\u7ec4\u7ec7\u5f39\u6027\u3002\u76ae\u80a4\u8868\u5c42\u7684\u73bb\u5c3f\u9178\u8c03\u8282\u5f97\u4e0d\u4ec5\u662f\u89d2\u8d28\u7ec6\u80de\u7684\u589e\u6b96\uff0c\u540c\u65f6\u635f\u4f24\u76ae\u80a4\u7684\u518d\u4e0a\u76ae\u5316\u3002\u57fa\u4e8e\u8fd9\u4e9b\u529f\u80fd\uff0c\u73bb\u5c3f\u9178\u88ab\u5f53\u4f5c\u586b\u5145\u7269\uff0c\u7528\u4f20\u7edf\u6ce8\u5c04\u5668\u7a7f\u8fc7\u795e\u7ecf\u548c\u8840\u7ba1\u6ce8\u5c04\u5230\u76ae\u4e0b \uff08\u56fe2\uff09\u3002\u4f46\u6ce8\u5c04\u73bb\u5c3f\u9178\u4f1a\u5bfc\u81f4\u75bc\u75db\uff0c\u7ea2\u80bf\u4ee5\u53ca\u8eab\u4f53\u7684\u8089\u82bd\u80bf\u5f02\u7269\u53cd\u5e94\u3002\u76ee\u524d\uff0c\u533b\u7528\u7684\u73bb\u5c3f\u9178\u4e3b\u8981\u901a\u8fc7\u57fa\u56e0\u6539\u7ec4\u7684\u67af\u8349\u82bd\u5b62\u6746\u83cc\u5408\u6210\uff0c\u4f46\u5b83\u4f7f\u7528\u5bff\u547d\u76f8\u5bf9\u6765\u8bb2\u6bd4\u8f83\u77ed\uff0c\u6240\u4ee5\u5236\u9020\u5de5\u827a\u901a\u8fc7\u5f15\u7528\u86cb\u767d\u94fe\u63d0\u9ad8\u5b83\u7684\u7a33\u5b9a\u6027 (Foschi et al., 1989; Smith and Ghosh, 1987)\u3002\u8fd9\u4e9b\u73bb\u5c3f\u9178\u7684\u5316\u5b66\u7279\u8d28\u95f4\u63a5\u51b3\u5b9a\u4e86\u6574\u5bb9\u7684\u9ad8\u6602\u8d39\u7528\uff0c\u540c\u65f6\u4e3a\u4e86\u89e3\u51b3\u8fd9\u79cd\u586b\u5145\u7269\u7684\u526f\u4f5c\u7528\uff0c\u8fd1\u671f\u7684\u7814\u7a76\u4e3b\u8981\u96c6\u4e2d\u5728\u5f00\u53d1\u65b0\u7684\u6ce8\u5c04\u8bbe\u5907\uff0c\u4f18\u5316\u6ce8\u5c04\u65b9\u6cd5\u548c\u5236\u9020\u5305\u542b\u5176\u5b83\u8c03\u63a7\u56e0\u5b50\u7684\u73bb\u5c3f\u9178\u586b\u5145\u7269(Mermin et al., 2016)\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-36324\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2016\/08\/3-30.png\" alt=\"3\" width=\"649\" height=\"278\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2016\/08\/3-30.png 649w, \/\/m.iemloyee.com\/wp-content\/uploads\/2016\/08\/3-30-300x129.png 300w\" sizes=\"(max-width: 649px) 100vw, 649px\" \/><\/p>\n<p style=\"text-align: center;\"><strong>\u56fe3 <\/strong>\u201c\u7b2c\u4e8c\u5c42\u808c\u80a4\u201d\u662f\u900f\u660e\u7684 \uff08\u5de6\u56fe\uff09\u3002\u548c\u53f3\u773c\u6bd4\u8f83\uff0c\u5728\u7528\u201c\u7b2c\u4e8c\u5c42\u808c\u80a4\u201d\u540e\u5de6\u773c\u7684\u773c\u888b\u4e0d\u89c1\u5566\uff08\u53f3\u56fe\uff09(Yu et al., 2016)<\/p>\n<p style=\"text-align: center;\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-40363\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2016\/08\/4-29-1.png\" alt=\"4-29\" width=\"600\" height=\"270\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2016\/08\/4-29-1.png 600w, \/\/m.iemloyee.com\/wp-content\/uploads\/2016\/08\/4-29-1-300x135.png 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/p>\n<p style=\"text-align: center;\"><strong>\u56fe4 <\/strong>\u5c06\u201c\u7b2c\u4e8c\u5c42\u808c\u80a4\u201d\u5e94\u7528\u5728\u773c\u89d2\u4e0b\u65b9\u533a\u57df\u65f6\uff0c\u5177\u4f53\u7684\u89c6\u89c9\u6548\u679c\u5bf9\u6bd4\u56fe(Yu et al., 2016)<\/p>\n<p style=\"text-align: center;\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-40365\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2016\/08\/5-24-2.png\" alt=\"5-24\" width=\"650\" height=\"427\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2016\/08\/5-24-2.png 650w, \/\/m.iemloyee.com\/wp-content\/uploads\/2016\/08\/5-24-2-300x197.png 300w\" sizes=\"(max-width: 650px) 100vw, 650px\" \/><\/p>\n<p style=\"text-align: center;\"><strong>\u56fe5 <\/strong>\u201c\u7b2c\u4e8c\u5c42\u808c\u80a4\u201d\u7a7f\u6234\u540e\u7684\u4e00\u4e9b\u4f7f\u7528\u6027\u80fd\u53c2\u6570(Yu et al., 2016)<\/p>\n<p>\u9ebb\u7701\u7406\u5de5\u6559\u6388Robert S. Langer \u7684\u7814\u7a76\u56e2\u961f\u548c\u5316\u5986\u54c1\u884d\u751f\u516c\u53f8Olivo\u521b\u9020\u6027\u5730\u5f00\u53d1\u51fa\u4e00\u79cd\u547d\u540d\u4e3a\u201c\u7b2c\u4e8c\u5c42\u808c\u80a4\u201d\u7684\u900f\u660e\u7684\u53ef\u7a7f\u6234\u5f0f\u805a\u5408\u7269(Yu et al., 2016)\u3002\u5b83\u80fd\u591f\u5ab2\u7f8e\u5e74\u8f7b\u7684\u81ea\u7136\u76ae\u80a4\uff0c\u62e5\u6709\u8f83\u597d\u7684\u5f39\u6027\u3001\u5149\u53cd\u5c04\u548c\u6563\u5c04\u6027\u80fd\u3002\u5b83\u7684\u5e94\u7528\u662f\u76f8\u5f53\u7b80\u5355\u65b9\u4fbf\u7684 \uff08\u56fe3\uff09\u3002\u9996\u5148\u5728\u4f60\u7684\u773c\u888b\u6216\u5176\u5b83\u76ae\u80a4\u4e0a\u6d82\u4e00\u5c42\u7c7b\u4f3c\u9762\u971c\u7684\u7845\u6811\u8102\u805a\u5408\u7269\uff0c\u7136\u540e\u518d\u5728\u4e0a\u9762\u62b9\u4e0a\u4e00\u5c42\u94c2\u50ac\u5316\u5242\uff0c\u94c2\u50ac\u5316\u5242\u4fc3\u4f7f\u5206\u5b50\u95f4\u5f62\u6210\u94fe\u63a5\u3002\u8fd9\u79cd\u7b2c\u4e8c\u5c42\u808c\u80a4\u4e0d\u4ec5\u80fd\u591f\u8212\u9002\u5730\u5b58\u5728\u4e8e\u8138\u4e0a\u8d85\u8fc724\u5c0f\u65f6\uff0c\u800c\u4e14\u53ef\u4ee5\u81ea\u7531\u547c\u5438\u3001\u9501\u4f4f\u6c34\u5206\u3001\u6563\u5c04\u5149\u7ebf\u3002\u9664\u4e86\u62e5\u6709\u4ee5\u4e0a\u7279\u6b8a\u6027\u80fd\uff0c\u8fd9\u79cd\u805a\u5408\u7269\u8fd8\u53ef\u4ee5\u6839\u636e\u5e74\u8f7b\u76ae\u80a4\u7684\u62c9\u4f38\u6027\u4ee5\u53ca\u6062\u590d\u6027\u56e0\u4eba\u800c\u5f02\u5730\u53bb\u8c03\u6574\u3002\u65e9\u671f\u7684\u8bd5\u9a8c\u6027\u7ed3\u679c\u8868\u660e\u5728\u773c\u888b\u5468\u56f4\u7528\u4e0a\u8fd9\u79cd\u201c\u7b2c\u4e8c\u5c42\u76ae\u80a4\u201d\u540e\uff0c\u773c\u5468\u7684\u76ae\u80a4\u53d8\u7d27\u81f4\u5e76\u4e14\u76b1\u7eb9\u4e5f\u968f\u4e4b\u51cf\u5c11\u3002\u7136\u800c\uff0c\u9700\u8981\u5f00\u5c55\u5927\u91cf\u7684\u4e34\u5e8a\u8bd5\u9a8c\u6765\u68c0\u9a8c\u8fd9\u79cd\u805a\u5408\u7269\u5bf9\u4eba\u4f53\u662f\u65e0\u5371\u5bb3\u7684\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-40372\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2016\/08\/6-23-1.png\" alt=\"6-23\" width=\"650\" height=\"469\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2016\/08\/6-23-1.png 650w, \/\/m.iemloyee.com\/wp-content\/uploads\/2016\/08\/6-23-1-300x216.png 300w\" sizes=\"(max-width: 650px) 100vw, 650px\" \/><\/p>\n<p style=\"text-align: center;\"><strong>\u56fe6 <\/strong>\u5728\u6b63\u5e38\u7684\u673a\u4f53\u6761\u4ef6\u4e0b\u76ae\u80a4\u53d7\u635f\u540e\u5f15\u8d77\u7684\u5feb\u901f\u4f24\u53e3\u4fee\u590d\u8fc7\u7a0b\uff0c\u4f46\u662f\u5728\u5fae\u751f\u7269\u7684\u611f\u67d3\u8fc7\u7a0b\u4e2d\uff0c\u8be5\u81ea\u52a8\u4fee\u590d\u8fc7\u7a0b\u4f1a\u53d7\u5230\u5e72\u6270\uff0c\u4ece\u800c\u4f1a\u8fdb\u4e00\u6b65\u5f15\u8d77\u4f24\u53e3\u7684\u6162\u6027\u708e\u75c7(Clark et al., 2007)<\/p>\n<p style=\"text-align: center;\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-40373\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2016\/08\/7-17-1.png\" alt=\"7-17\" width=\"650\" height=\"508\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2016\/08\/7-17-1.png 650w, \/\/m.iemloyee.com\/wp-content\/uploads\/2016\/08\/7-17-1-300x234.png 300w\" sizes=\"(max-width: 650px) 100vw, 650px\" \/><\/p>\n<p style=\"text-align: center;\"><strong>\u56fe7 <\/strong>\u4f53\u5185\u5408\u6210\u7684\u65e0\u7ec6\u80de\u751f\u7269\u6750\u6599\uff08\u5982\u751f\u7269\u9ad8\u805a\u7269\uff0c\u6c34\u51dd\u80f6\uff09\u5e94\u7528\u4e8e\u7ec4\u7ec7\u5668\u5b98\u7684\u4f24\u53e3\u4fee\u590d(Clark et al., 2007)<\/p>\n<p style=\"text-align: center;\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-40375\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2016\/08\/8-11-1.png\" alt=\"8-11\" width=\"650\" height=\"431\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2016\/08\/8-11-1.png 650w, 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2007)<\/p>\n<p>\u9020\u6210\u76ae\u80a4\u4e22\u5931\u7684\u8fd8\u6709\u70e7\u4f24\u548c\u7531\u7cd6\u5c3f\u75c5\u7b49\u5f15\u8d77\u7684\u6e83\u75a1\u3002\u5728\u8fd9\u4e9b\u75c5\u4f8b\u4e2d\uff0c\u4e3b\u8981\u89e3\u51b3\u7684\u96be\u9898\u662f\u518d\u751f\u51fa\u65e0\u75a4\u75d5\u3001\u4e0d\u4f1a\u4ea7\u751f\u7622\u75d5\u7624\u548c\u5177\u6709\u826f\u597d\u529f\u80fd\u7684\u76ae\u80a4\u3002\u5f53\u524d\u5e02\u573a\u4e0a\u5b58\u5728\u7740\u4e00\u4e9b\u5305\u542b\u91cd\u7ec4\u751f\u957f\u56e0\u5b50\u7684\u7ef7\u5e26\u3002\u5b83\u4eec\u53ef\u4ee5\u4fc3\u4f7f\u4f24\u53e3\u6108\u5408\uff0c\u4f46\u5374\u9700\u8981\u6bcf\u5929\u6216\u8005\u81f3\u5c11\u4e24\u5929\u66f4\u6362\u4e00\u6b21\uff0c\u9020\u6210\u5e94\u7528\u7684\u4e0d\u65b9\u4fbf\u3002\u6839\u636e\u518d\u751f\u7684\u76ae\u80a4\u5fc5\u987b\u540c\u65f6\u6ee1\u8db3\u529b\u5b66\u6027\u80fd\u548c\u751f\u7269\u6d3b\u6027\u7684\u8981\u6c42\uff0c\u7814\u7a76\u8005\u4eec\u63d0\u51fa\u4e86\u4f53\u5916\u6216\u8005\u4f53\u5185\u5236\u9020\u57fa\u4e8e\u7ec4\u7ec7\u5de5\u7a0b\u7684\u76ae\u80a4\u66ff\u4ee3\u7269(Clark et al., 2007)\u3002\u4f53\u5916\u5408\u6210\u7684\u65b9\u6cd5\u4e3b\u8981\u6307\u901a\u8fc7\u7ec4\u7ec7\u57f9\u517b\u6216\u8005\u7ec6\u80de\u53cd\u5e94\u5668\u6765\u57f9\u517b\u5e26\u6709\u7ec6\u80de\u7684\u5408\u6210\u76ae\u80a4\u3002\u7ec4\u7ec7\u57f9\u517b\u975e\u5e38\u5177\u6709\u6311\u6218\u6027\uff0c\u96be\u4ee5\u63a7\u5236\u7684\u57f9\u517b\u73af\u5883\u4f1a\u4fc3\u4f7f\u5408\u6210\u76ae\u80a4\u9000\u5316\uff0c\u5982\u7ec6\u80de\u6b7b\u4ea1\uff0c\u5408\u6210\u76ae\u80a4\u7684\u7ec4\u6210\u548c\u7ed3\u6784\u4e5f\u5f88\u96be\u548c\u81ea\u7136\u76ae\u80a4\u76f8\u5ab2\u7f8e\u3002\u4f53\u5185\u5408\u6210\u7684\u65e0\u7ec6\u80de\u751f\u7269\u6750\u6599\uff08\u5982\u751f\u7269\u9ad8\u805a\u7269\uff0c\u6c34\u51dd\u80f6\uff09\u9996\u5148\u80fd\u591f\u4fdd\u62a4\u76ae\u80a4\u5185\u7684\u5668\u5b98\uff0c\u5f53\u690d\u5165\u5230\u4eba\u4f53\u540e\u53ef\u4ee5\u62db\u52df\u7ec6\u80de\u5408\u6210\u65b0\u7684\u76ae\u80a4\u5e76\u5728\u8fd9\u4e00\u8fc7\u7a0b\u4e2d\u4e0d\u65ad\u5206\u89e3\u6389\u3002\u8fd9\u7c7b\u4ea7\u54c1\u7684\u5e94\u7528\u4e3b\u8981\u5b58\u5728\u7740\u5f02\u7269\u53cd\u5e94\u3001\u673a\u68b0\u5f3a\u5ea6\u5c0f\u548c\u5728\u539f\u751f\u4e0e\u65b0\u751f\u7684\u76ae\u80a4\u95f4\u65e0\u6cd5\u5f62\u6210\u201c\u65e0\u7f1d\u201d\u8fde\u63a5\u7684\u95ee\u9898\u3002<\/p>\n<p>\u5728\u611f\u6069\u65e0\u6570\u7814\u7a76\u8005\u4eec\u63a8\u52a8\u76ae\u80a4\u5de5\u7a0b\u6280\u672f\u4e0d\u65ad\u53d1\u5c55\u4e0e\u5b8c\u5584\u7684\u540c\u65f6\uff0c\u6211\u4eec\u4e5f\u9762\u4e34\u7740\u600e\u6837\u53ef\u4ee5\u5982\u5927\u81ea\u7136\u822c\u5236\u9020\u65e0\u7455\u75b5\u5e76\u62e5\u6709\u9002\u5ea6\u5f39\u6027\u4e0e\u97e7\u6027\u7684\u5408\u6210\u76ae\u80a4\u7684\u6311\u6218\u3002\u867d\u7136\u8fd9\u5df2\u7ecf\u6210\u4e3a\u81ed\u5927\u8857\u7684\u8bba\u8c03\uff0c\u4f46\u4f5c\u8005\u8fd8\u662f\u60f3\u5f3a\u8c03\u7ec4\u7ec7\/\u76ae\u80a4\u5de5\u7a0b\u7684\u8fdb\u6b65\u9700\u8981\u7814\u7a76\u8005\u4eecbrainstorm\u62d3\u5bbd\u5b9e\u73b0\u9014\u5f84\u5e76\u4e14\u52a0\u5f3a\u5404\u4e2a\u9886\u57df\uff08\u5982\u751f\u7269\u3001\u5316\u5b66\u3001\u533b\u5b66\u3001\u7269\u7406\u3001\u5de5\u7a0b\uff09\u7684\u5408\u4f5c\u3002\u6216\u8bb8\u5728\u672a\u6765\u7684\u4e8c\u4e09\u5341\u5e74\u91cc\uff0c\u70e7\u4f24\u7684\u75c5\u4eba\u672f\u540e\u4e0d\u518d\u6709\u75a4\u75d5\uff0c\u80e1\u6b4c\u6b27\u5df4\u56e0\u8f66\u7978\u800c\u9020\u6210\u7684\u773c\u76ae\u75a4\u75d5\u4e5f\u4f1a\u6d88\u5931\u4e0d\u89c1\uff0c\u66f4\u4ee4\u4eba\u6fc0\u52a8\u7684\u662f\uff0c\u5e73\u51e1\u5982\u4f60\u6211\u518d\u4e5f\u4e0d\u7528\u4e3a\u76b1\u7eb9\u722c\u6ee1\u989d\u5934\u800c\u4f24\u8111\u7b4b\uff0c\u53ef\u4ee5\u4f18\u96c5\u800c\u7f8e\u4e3d\u7684\u8001\u53bb\u3002<\/p>\n<p><strong>\u53c2\u8003\u6587\u732e\uff1a<\/strong><\/p>\n<p>[1] Rushmer, R. F.et al. The skin. Science \u2028154, 343\u2013348 (1966).<\/p>\n<p>[2] \u2028Xu, S. <em>et al<\/em>. Soft microfluidic assemblies of sensors, circuits, and radios for the \u2028skin. <em>Science<\/em> 344, 70\u201374 (2014).<\/p>\n<p>[3] Clark, R.A.et al. Tissue engineering for cutaneous wounds. Journal of Investigative Dermatology 127, 1018-1029(2007).<\/p>\n<p>[4] Foschi, D. et al. Hyaluronic acid prevents oxygen free-radical damage to granulation tissue: a study in rats. International journal of tissue reactions 12, 333-339(1989).<\/p>\n<p>[5] Mermin, D. et al.\u00a0A case of hyaluronic acid injections triggering cutaneous sarcoidosis at previously treated sites. Journal of the European Academy of Dermatology and Venereology 1468-3083, (2016).<\/p>\n<p>[6] Smith, M. et al. The synthesis of hyaluronic acid by human synovial fibroblasts is influenced by the nature of the hyaluronate in the extracellular environment. Rheumatology international 7, 113-122(1987).<\/p>\n<p>[7] Yu, B. et al. An elastic second skin.Nature materials 15(8), 911-8(2016).<\/p>\n<p>\u672c\u6587\u4ec5\u662f\u4e00\u5bb6\u4e4b\u8a00\uff0c\u5e0c\u671b\u5404\u4f4d\u8bfb\u8005\u8f7b\u62cd\uff0c\u6b22\u8fce\u63a2\u8ba8\u4e0e\u8865\u5145\u3002<\/p>\n<p>\u672c\u6587\u7531\u7f8e\u56fd\u5723\u8def\u6613\u65af\u534e\u76db\u987f\u5927\u5b66\u751f\u7269\u5de5\u7a0b\u7cfbPhD. 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