{"id":35071,"date":"2016-08-22T08:00:17","date_gmt":"2016-08-22T00:00:17","guid":{"rendered":"\/\/m.iemloyee.com\/?p=35071"},"modified":"2016-08-21T22:28:38","modified_gmt":"2016-08-21T14:28:38","slug":"%e9%a1%b6%e5%88%8a%e5%8a%a8%e6%80%81-%e7%94%9f%e7%89%a9%e6%9d%90%e6%96%99%e5%89%8d%e6%b2%bf%e6%9c%80%e6%96%b0%e7%a7%91%e7%a0%94%e6%88%90%e6%9e%9c%e7%b2%be%e9%80%89%e3%80%90%e7%ac%ac18%e6%9c%9f","status":"publish","type":"post","link":"\/\/m.iemloyee.com\/?p=35071","title":{"rendered":"\u9876\u520a\u52a8\u6001 | Nature\u5b50\u520a\/AM\u7b49\u751f\u7269\u6750\u6599\u524d\u6cbf\u6700\u65b0\u79d1\u7814\u6210\u679c\u7cbe\u9009\u3010\u7b2c18\u671f\u3011"},"content":{"rendered":"

\u672c\u671f\u7cbe\u9009\u9884\u89c8<\/strong>\uff1aAngew. Chem. Int. Ed.\u00a0\u4e2d\u79d1\u9662\u957f\u6625\u5e94\u5316\u6240\uff1a\u94dc\u79bb\u5b50\uff08Cu2+\uff09\u4e0e\u77f3\u58a8\u76f8\u6c2e\u5316\u78b3\uff08g-C3N4\uff09\u7ed3\u5408\u4ea7\u751f\u6d3b\u6027\u6c27\u548c\u51cf\u5c11\u8c37\u80f1\u7518\u80bd\u4ee5\u6539\u5584\u5149\u52a8\u529b\u6cbb\u7597\uff1bJACS \u787c\u9178\uff1a\u53d7\u751f\u7269\u542f\u53d1\u5f97\u5230\u7684\u589e\u5f3a\u8367\u5149 NADH\u63a2\u9488\u7075\u654f\u5ea6\u548c\u9009\u62e9\u6027\u7684\u7b56\u7565\uff1bACS Nano \u6297\u5fae\u751f\u7269\u56e2\u7c07\uff1aAg\u7eb3\u7c73\u56e2\u7c07\u4e0e\u8fbe\u6258\u9709\u7d20\u7ed3\u5408\uff1bACS Nano \u4eb2\u6c34\u6539\u6027\u7684\u91d1\uff08111\uff09\u4e0a\u5f62\u6210\u6709\u5e8f\u78f7\u8102\u5355\u5c42\uff1bACS Nano \u91cd\u590d\u6027\u6444\u5165\u767d\u70ad\u9ed1\u901a\u8fc7\u72ec\u7279\u7684\u6784\u6548\u5173\u7cfb\u4ee5\u53ca\u751f\u7269\u6301\u4e45\u6027\u5bfc\u81f4\u80ba\u90e8\u7ea4\u7ef4\u5316\u4f5c\u7528\uff1bAdv. Mater. DNA\u7ec4\u88c5\u7684\u91d1\u7eb3\u7c73\u68d2\u8d85\u7ed3\u6784\u8c03\u63a7\u836f\u7269\u7684\u8d1f\u8f7d\u548c\u91ca\u653e\uff1bACS Nano \u591a\u529f\u80fd\u78c1\u6027\u8102\u8d28\u4f53\u7684\u6709\u5e8f\u53ef\u63a7\u91ca\u653e\uff1bAdv. Mater. \u7ea2\u8272\u8367\u5149\u56e2\u6709\u673a\u7eb3\u7c73\u5fae\u9897\u7c92\u7528\u6765\u8bc4\u4f30\u8840\u8111\u5c4f\u969c\u7684\u635f\u574f\u7a0b\u5ea6\uff1bAngew. Chem. Int. Ed. \u4e0a\u8f6c\u6362\u7eb3\u7c73\u7c92\u5b50\u89e3\u51b3\u6d3b\u7ec6\u80de\u5185\u86cb\u767d\u8d28\u7684\u76f8\u4e92\u5f71\u54cd\uff1bNano Lett. \u5fae\u6d41\u4f53\u751f\u4ea7\u7684\u80f6\u539f\u86cb\u767d\u7ea4\u7ef4\u5c55\u73b0\u4f18\u5f02\u7684\u673a\u68b0\u6027\u80fd\uff1bAdv. Mater. \u53ef\u7528\u4e8e\u5fae\u521b\u624b\u672f\u7684\u8d85\u5206\u5b50\u91d1\u5c5e\u751f\u7269\u9ecf\u5408\u5242\uff1bNat. Nanotech. \u4e00\u7ef4DNA\u51dd\u805a\u3002<\/p>\n

1\u3001Angew. Chem. Int. Ed. \u94dc\u79bb\u5b50\uff08Cu2+\uff09\u4e0e\u77f3\u58a8\u76f8\u6c2e\u5316\u78b3\uff08g-C3N4\uff09\u7ed3\u5408\u4ea7\u751f\u6d3b\u6027\u6c27\u548c\u51cf\u5c11\u8c37\u80f1\u7518\u80bd\u4ee5\u6539\u5584\u5149\u52a8\u529b\u6cbb\u7597<\/strong><\/p>\n

\"\u56fe\u72471\"<\/p>\n

\u56fe1<\/strong> g-C3N4\u4f5c\u4e3a\u5149\u654f\u5242\u7528\u4e8e\u5149\u52a8\u529b\u6cbb\u7597\u4ee5\u53caCu2+- g-C3N4\u534f\u540c\u4f5c\u7528\u56fe\u89e3<\/p>\n

\u77f3\u58a8\u76f8\u6c2e\u5316\u78b3\uff08g-C3N4\uff09\u5728\u5149\u52a8\u529b\u6cbb\u7597\u4e2d\u7528\u4f5c\u5149\u654f\u5242\u4ee5\u4ea7\u751f\u6d3b\u6027\u6c27\uff08ROS\uff09\uff0c\u4f46\u662f\u5b83\u7684\u6cbb\u7597\u6548\u7387\u8fd8\u4e0d\u5c3d\u4eba\u610f\u3002\u5176\u4e2d\u6700\u5927\u7684\u96be\u70b9\u5728\u4e8e\u764c\u75c7\u7ec6\u80de\u8c37\u80f1\u7518\u80bd\uff08GSH\uff09\u7684\u8fc7\u5206\u8868\u8fbe\uff0c\u4f7f\u5f97ROS\u5728\u5230\u8fbe\u9776\u5fc3\u4f4d\u7f6e\u524d\u6d88\u8017\u6b86\u5c3d\uff0c\u5f71\u54cd\u5149\u52a8\u529b\u6cbb\u7597\u7684\u6548\u679c\u3002<\/p>\n

\u8fd1\u65e5\uff0c\u6765\u81ea\u4e2d\u79d1\u9662\u957f\u6625\u5e94\u5316\u6240\u7684\u4efb\u52b2\u677e\u7814\u7a76\u5458\uff08\u901a\u8baf\u4f5c\u8005\uff09\u548c\u66f2\u6653\u521a\u7814\u7a76\u5458\uff08\u901a\u8baf\u4f5c\u8005\uff09\u7b49\u4eba\u53d1\u73b0Cu2+\u4e0eGSH\u5171\u73b0\u53ef\u4ee5\u901a\u8fc7\u91d1\u5c5e\u8fd8\u539f\u53cd\u5e94\u63d0\u9ad8\u50ac\u5316\u6548\u7387\uff0cCu2+\u9650\u5236\u78f7\u8102\u9170\u4e59\u9187\u80fa\u4e2d\u7684\u80fa\u4e0e\u8fc7\u6c27\u5316\u6c22\uff08H2O2\uff09\u53d1\u751f\u53cd\u5e94\u589e\u52a0ROS\u7684\u6d53\u5ea6\u3002\u901a\u8fc7\u8fd9\u79cd\u91d1\u5c5e\u79bb\u5b50\u4e0e\u5149\u654f\u5242\u53d1\u751f\u6c27\u5316\u8fd8\u539f\u53cd\u5e94\u4f7f\u5f97GSH\u7684\u964d\u4f4e\u4ece\u800c\u63d0\u9ad8\u4e86\u764c\u75c7\u6cbb\u7597\u7684\u6548\u7387\u3002<\/p>\n

\u6587\u732e\u94fe\u63a5\uff1a<\/strong>Copper(II)\u2013Graphitic Carbon Nitride Triggered Synergy: Improved ROS Generation and Reduced Glutathione Levels for Enhanced Photodynamic Therapy<\/a>\uff08Angew. Chem. Int. Ed.\uff0c2016\uff0cDOI: 10.1002\/anie.201605509\uff09<\/p>\n

2\u3001JACS \u787c\u9178\uff1a\u53d7\u751f\u7269\u542f\u53d1\u5f97\u5230\u7684\u589e\u5f3a\u8367\u5149 NADH\u63a2\u9488\u7075\u654f\u5ea6\u548c\u9009\u62e9\u6027\u7684\u7b56\u7565<\/strong><\/p>\n

\"\u56fe\u72472\"<\/p>\n

\u56fe2 <\/strong>\uff08A\uff09\u9176\u50ac\u5316\u8367\u5149\u63a2\u9488\u4e0e\u76ee\u6807\u5206\u5b50\u7684\u53cd\u5e94\uff08B\uff09\u6536\u9176\u50ac\u5316\u53cd\u5e94\u8bbe\u8ba1\u7684\u8367\u5149\u63a2\u9488<\/p>\n

\u8367\u5149\u63a2\u9488\u662f\u8bc6\u522b\u751f\u7269\u5206\u5b50\u7684\u91cd\u8981\u5de5\u5177\uff0c\u4f46\u662f\u7531\u4e8e\u67d0\u4e9b\u5206\u5b50\u7684\u7ed3\u6784\u975e\u5e38\u975e\u5e38\u590d\u6742\uff0c\u7528\u5177\u5907\u7075\u654f\u5ea6\u548c\u9009\u62e9\u6027\u7684\u5c0f\u5206\u5b50\u8367\u5149\u63a2\u9488\u6765\u68c0\u6d4b\u4ed6\u4eec\u8fd8\u975e\u5e38\u56f0\u96be\u3002<\/p>\n

\u6700\u8fd1\uff0c\u65b0\u52a0\u5761\u56fd\u7acb\u5927\u5b66\u7684Young-Tae Chang\uff08\u901a\u8baf\u4f5c\u8005\uff09\u7b49\u4eba\u53d7\u5230\u9176\u50ac\u5316\u53cd\u5e94\u7684\u542f\u53d1\u8bbe\u8ba1\u4e86\u4e00\u79cd\u7ed3\u5408-\u53cd\u5e94\u4e24\u6b65\u6cd5\u6765\u63d0\u9ad8\u8367\u5149\u63a2\u9488\u7684\u7075\u654f\u5ea6\u548c\u9009\u62e9\u6027\u3002\u4ed6\u4eec\u5c06\u787c\u9178\u4e0e\u8367\u5149\u7269\u8d28\u76f8\u8fde\uff0c\u7528\u787c\u9178\u6765\u4e0e NADH\uff08\u8fd8\u539f\u578b\u70df\u9170\u80fa\u817a\u560c\u5464\u9178\u4e8c\u6838\u82f7\u9178\uff09\u7ed3\u5408\uff0c\u52a0\u901f\u4e86\u8367\u5149\u7269\u8d28\u4e0eNADH\u4e4b\u95f4\u7684\u53cd\u5e94\uff0c\u4ece\u800c\u63d0\u9ad8\u4e86\u7075\u654f\u5ea6\u548c\u9009\u62e9\u6027\u3002\u4f7f\u7528\u8fd9\u79cd\u7b56\u7565\u4ed6\u4eec\u4e0d\u4ec5\u5f97\u5230\u4e86\u4e00\u79cd\u4fdd\u5065\u4ea7\u54c1\u4e2dNADH\u7684\u542b\u91cf\uff0c\u8fd8\u8bc4\u4f30\u4e86\u6d3b\u7ec6\u80de\u4e2dNADH\u7684\u6c34\u5e73\uff0c\u56e0\u6b64\uff0c\u8fd9\u79cd\u7b56\u7565\u4e0d\u4f46\u6709\u52a9\u4e8e\u7814\u7a76NADH\u5728\u751f\u7269\u7cfb\u7edf\u4e2d\u7684\u4f5c\u7528\uff0c\u8fd8\u80fd\u7528\u6765\u68c0\u6d4b\u5176\u5b83\u7684\u590d\u6742\u751f\u7269\u5206\u5b50\u3002<\/p>\n

\u6587\u732e\u94fe\u63a5\uff1a<\/strong>Boronic Acid: A Bio-Inspired Strategy To Increase the Sensitivity and Selectivity of Fluorescent NADH Probe<\/a>\uff08JACS\uff0c2016\uff0cDOI\uff1a10.1021\/jacs.6b05810\uff09<\/p>\n

3\u3001ACS Nano \u6297\u5fae\u751f\u7269\u56e2\u7c07\uff1aAg\u7eb3\u7c73\u56e2\u7c07\u4e0e\u8fbe\u6258\u9709\u7d20\u7ed3\u5408<\/strong><\/p>\n

\"\u56fe\u72473\"<\/p>\n

\u56fe3 <\/strong>\uff08a\uff09AgNCs\uff08\u9ed1\u7ebf\uff09\u4e0eD-AgNCs\uff08\u7ea2\u7ebf\uff09\u7684\u5149\u5438\u6536\uff08\u5b9e\u7ebf\uff09\u548c\u5149\u6fc0\u53d1\uff08\u865a\u7ebf\uff09\u5149\u8c31\uff08b\uff09AgNCs\u548cD-AgNCs\u7684\u7c92\u5f84\u5206\u5e03<\/p>\n

\u8fbe\u6258\u9709\u7d20\u662f\u4ec5\u5b58\u7684\u5c11\u6570\u80fd\u6297\u51fb\u591a\u91cd\u8010\u836f\u6027\u7ec6\u83cc\u7684\u836f\u7269\uff0c\u76ee\u524d\u7ec6\u83cc\u5bf9\u5b83\u7684\u62b5\u6297\u80fd\u529b\u8fd8\u5f88\u5dee\uff0c\u4f46\u662f\u5728\u589e\u52a0\uff0c\u5e76\u4e14\u5728\u4e34\u5e8a\u5e94\u7528\u65f6\u5b83\u7684\u4f7f\u7528\u65f6\u95f4\u8981\u8d85\u8fc720\u5c0f\u65f6\u3002\u9ad8\u5242\u91cf\u3001\u6cbb\u7597\u65f6\u95f4\u957f\u52a0\u4e0a\u6740\u83cc\u673a\u5236\u5355\u4e00\uff0c\u662f\u7ec6\u83cc\u53d1\u5c55\u51fa\u8010\u836f\u6027\u7684\u901a\u5e38\u539f\u56e0\uff0c\u6240\u4ee5\u53ef\u4ee5\u9884\u89c1\u8fbe\u6258\u9709\u7d20\u7684\u6297\u83cc\u6548\u679c\u4f1a\u8d8a\u6765\u8d8a\u5dee\u3002<\/p>\n

\u6700\u8fd1\uff0c\u65b0\u52a0\u5761\u56fd\u7acb\u5927\u5b66\u7684Magdiel I. Setyawati\uff08\u901a\u8baf\u4f5c\u8005\uff09\u3001David Tai Leong\uff08\u901a\u8baf\u4f5c\u8005\uff09\u548c Jianping Xie\uff08\u901a\u8baf\u4f5c\u8005\uff09\u7b49\u4eba\u62a5\u5bfc\u4e86\u4e00\u79cd\u5c06Ag\u7eb3\u7c73\u56e2\u7c07\uff08AgNCs\uff09\u4e0e\u8fbe\u6258\u9709\u7d20\u901a\u8fc7\u5171\u4ef7\u952e\u7ed3\u5408\u8d77\u6765\u7684\u6297\u83cc\u836f\u7269\uff08D-AgNCs\uff09\uff0cD-AgNCs\u80fd\u6709\u6548\u7834\u574f\u7ec6\u83cc\u7684\u7ec6\u80de\u819c\u4f7f\u81ea\u5df1\u80fd\u591f\u5f88\u5bb9\u6613\u8fdb\u5165\u7ec6\u80de\u5185\uff0c\u968f\u540e\u7834\u574f\u7ec6\u83cc\u7684DNA\u3002D-AgNCs\u7684\u6548\u679c\u6bd4\u7528\u7b49\u91cfAg\u548c\u8fbe\u6258\u9709\u7d20\u6df7\u5408\u7269\u7684\u6548\u679c\u597d\uff0c\u8fd9\u5f52\u529f\u4e8e\u5728D-AgNCs\u4e2dAg\u548c\u8fbe\u6258\u9709\u7d20\u7d27\u7d27\u6328\u5728\u4e00\u8d77\uff0c\u589e\u5f3a\u4e86\u5b83\u4eec\u7684\u534f\u8c03\u4f5c\u7528\u3002<\/p>\n

\u6587\u732e\u94fe\u63a5\uff1a<\/strong>Antimicrobial Cluster Bombs: Silver Nanoclusters Packed with Daptomycin<\/a>\uff08ACS Nano\uff0c2016\uff0cDOI\uff1a10.1021\/acsnano.6b03862\uff09<\/p>\n

4\u3001ACS Nano \u4eb2\u6c34\u6539\u6027\u7684\u91d1\uff08111\uff09\u4e0a\u5f62\u6210\u6709\u5e8f\u78f7\u8102\u5355\u5c42<\/strong><\/p>\n

\"4\"<\/p>\n

\u56fe4 <\/strong>POPC\u4ee5\u53ca3-MPA\u5728\u91d1\uff08111\uff09\u9762\u6210\u5f62\u7684\u5f62\u6001\u793a\u610f\u56fe<\/p>\n

\u78f7\u8102\u5206\u5b50\u662f\u7ec6\u80de\u819c\u7684\u91cd\u8981\u6210\u5206\uff0c\u8fd9\u79cd\u7269\u8d28\u7684\u957f\u5ea6\u901a\u5e38\u57282-3\u7eb3\u7c73\uff0c\u62e5\u6709\u4e00\u4e2a\u4eb2\u6c34\u5934\u57fa\u56e2\u4ee5\u53ca\u4e24\u6761\u758f\u6c34\u78b3\u94fe\u3002\u957f\u671f\u4ee5\u6765\uff0c\u7814\u7a76\u4eba\u5458\u4e00\u76f4\u5e0c\u671b\u80fd\u591f\u5728\u57c3\u7c73\u5c3a\u5ea6\u4e0a\u89c2\u5bdf\u76f8\u4e92\u4e4b\u95f4\u53d1\u751f\u53cd\u5e94\u7684\u5355\u4e2a\u78f7\u8102\u5206\u5b50\u7684\u7279\u5f81\u3002\u73b0\u6709\u7684\u663e\u5fae\u5b66\uff0c\u5305\u62ec\u4f5c\u4e3a\u89c2\u5bdf\u751f\u7269\u5927\u5206\u5b50\u9996\u9009\u7684\u626b\u63cf\u63a2\u9488\u6280\u672f\uff08STM\uff09\u548c\u539f\u5b50\u529b\u663e\u5fae\u6280\u672f\uff08AFM\uff09\uff0c\u90fd\u9700\u8981\u4ee5\u5e73\u6574\u3001\u521a\u786c\u7684\u56fa\u4f53\u8868\u9762\u4f5c\u4e3a\u64cd\u4f5c\u5e73\u53f0\u3002<\/p>\n

\u65e5\u672c\u7406\u5316\u5b66\u7814\u7a76\u6240 T. Yamada\uff08\u901a\u8baf\u4f5c\u8005\uff09\u56e2\u961f\u6784\u60f3\u4e86\u901a\u8fc7\u6eb6\u6db2\u4e0e\u78f7\u8102\u7684\u758f\u6c34\u4f5c\u7528\u4fc3\u4f7f\u4eb2\u6c34\u6539\u6027\u7684\u91d1\uff08111\uff09\u8868\u9762\u548c\u78f7\u8102\u5206\u5b50\u4eb2\u6c34\u5934\u4e4b\u95f4\u80fd\u591f\u76f8\u4e92\u9760\u8fd1\u7684\u5b9e\u9a8c\u601d\u8def\u3002\u6839\u636e\u8fd9\u4e2a\u8bbe\u8ba1\u601d\u8def\uff0c\u7814\u7a76\u4eba\u5458\u75283-\u5def\u57fa\u4e19\u9178\uff083-MPA\uff09\u6539\u6027\u91d1\uff08111\uff09\u9762\uff0c\u5e76\u5c06\u5176\u6d78\u6ca1\u5728\u5375\u78f7\u8102POPC\u7eb3\u7c73\u9897\u7c92\u60ac\u6d6e\u6db2\u4e2d\u3002\u5728\u5176\u540e\u7684\u7535\u5316\u5b66STM\u8868\u5f81\u8fc7\u7a0b\u4e2d\uff0c\u7814\u7a76\u4eba\u5458\u89c2\u5bdf\u5230\u4e863-MPA\u5728\u91d1\u8868\u9762\u5f62\u6210\u5355\u5c42\u3001POPC\u56ca\u6ce1\u878d\u5408\u7684\u75d5\u8ff9\u4ee5\u53caPOPC\u5355\u5c42\u5728\u91d1\u8868\u9762\u5f62\u6210\u73af\u72b6\u4ee5\u53ca\u6a61\u80f6\u5708\u72b6\u7279\u5f81\u5f62\u8c8c\u3002<\/p>\n

\u6587\u732e\u94fe\u63a5\uff1a<\/strong>Permanent excimer superstructures by supramolecular networking of metal quantum clusters<\/a>\uff08ACS Nano\uff0c2016\uff0cDOI: 10.1021\/acsnano.6b03421\uff09<\/p>\n

5\u3001ACS Nano \u00a0\u91cd\u590d\u6027\u6444\u5165\u767d\u70ad\u9ed1\u901a\u8fc7\u72ec\u7279\u7684\u6784\u6548\u5173\u7cfb\u4ee5\u53ca\u751f\u7269\u6301\u4e45\u6027\u5bfc\u81f4\u80ba\u90e8\u7ea4\u7ef4\u5316\u4f5c\u7528<\/strong><\/p>\n

\"5\"<\/p>\n

\u56fe5 <\/strong>\u9f20\u79d1\u52a8\u7269\u80ba\u90e8\u5bf9\u4e0d\u540c\u767d\u70ad\u9ed1\u5242\u91cf\u7ba1\u7406\u7684\u80ba\u75c5\u8bc4\u4f30<\/p>\n

\u6c14\u76f8\u4e8c\u6c27\u5316\u7845\uff08fumed silica\uff09\u53c8\u79f0\u767d\u70ad\u9ed1\uff0c\u662f\u7528\u9014\u5e7f\u6cdb\u7684\u6c14\u6eb6\u80f6\u6750\u6599\u3002\u6839\u636e\u7f8e\u56fdFDA\u7684\u5b9a\u4e49\uff0c\u4e00\u822c\u8ba4\u4e3a\u5408\u6210\u7684\u975e\u6676\u7845\uff08SAS\uff09\u8bf8\u5982\u767d\u70ad\u9ed1\u3001\u7845\u51dd\u80f6\u7b49\u5747\u662f\u201c\u5b89\u5168\u53ef\u9760\uff08GRAS\uff09\u201d\u7684\u3002\u7136\u800c\u8fd1\u6765\u7684\u7814\u7a76\u53d1\u73b0\uff0c\u5982\u679c\u5c06\u4e0d\u540c\u79cd\u7c7b\u7684SAS\u5728\u6784\u6548\u5173\u7cfb\uff08SAR\uff09\u5c42\u9762\u4e0a\u8fdb\u884c\u6bd4\u8f83\u7684\u8bdd\uff0c\u767d\u70ad\u9ed1\u5728\u4ea7\u54c1\u5b89\u5168\u4e0a\u4f1a\u8868\u73b0\u51fa\u4e0e\u5176\u4ed6SAS\u622a\u7136\u4e0d\u540c\u7684\u7269\u7406\u5316\u5b66\u6027\u8d28\u3002\u66f4\u8fdb\u4e00\u6b65\u5730\u8bf4\uff0c\u5728\u5982\u5de5\u5382\u8f66\u95f4\u7b49\u516c\u5171\u573a\u6240\u91cd\u590d\u6027\u5730\u66b4\u9732\u5728\u6d3b\u6027\u767d\u70ad\u9ed1\u73af\u5883\u4e2d\u662f\u5426\u6709\u53ef\u80fd\u63d0\u9ad8\u60a3\u4e0a\u6162\u6027\u80ba\u75c5\u7684\u98ce\u9669\uff1f<\/p>\n

\u52a0\u5dde\u5927\u5b66\u6d1b\u6749\u77f6\u5206\u6821\u7684T. Xia\uff08\u901a\u8baf\u4f5c\u8005\uff09\u548cA. E. Nel\uff08\u901a\u8baf\u4f5c\u8005\uff09\u7b49\u4eba\u6bd4\u8f83\u4e86\u767d\u70ad\u9ed1\u5355\u5242\u91cf\u548c\u91cd\u590d\u6027\u5242\u91cf\u7ba1\u7406\u5bf9\u9f20\u79d1\u52a8\u7269\u80ba\u90e8\u635f\u4f24\u4ee5\u53caNLRP3\u6d3b\u6027\u7684\u5f71\u54cd\u3002\u5b9e\u9a8c\u8bc1\u660e\u5242\u91cf\u7ba1\u7406\u65b9\u5f0f\u7684\u5dee\u5f02\u80fd\u591f\u8bf1\u5bfc\u4e9a\u6162\u6027\u80ba\u90e8\u635f\u4f24\u51fa\u73b0\u4e0e\u5426\u3002\u6b64\u5916\uff0c\u901a\u8fc7\u63ba\u6742\u949b\u5143\u7d20\uff0c\u767d\u70ad\u9ed1\u5bf9\u8eab\u4f53\u7684\u6709\u5bb3\u4f5c\u7528\u5c06\u88ab\u6709\u6548\u5730\u51cf\u8f7b\u3002<\/p>\n

\u6587\u732e\u94fe\u63a5\uff1a<\/strong>Repetitive Dosing of Fumed Silica Leads to Profibrogenic Effects through Unique Structure\u2013Activity Relationships and Biopersistence in the Lung<\/a>\uff08ACS Nano\uff0c2016\uff0c DOI: 10.1021\/acsnano.6b04143\uff09<\/p>\n

6\u3001Adv. Mater. DNA\u7ec4\u88c5\u7684\u91d1\u7eb3\u7c73\u68d2\u8d85\u7ed3\u6784\u8c03\u63a7\u836f\u7269\u7684\u8d1f\u8f7d\u548c\u91ca\u653e<\/strong><\/p>\n

\"6\"<\/p>\n

\u56fe6 <\/strong>\u6838-\u536b\u661f\u7ed3\u6784\u836f\u7269\u8f7d\u4f53\u8bbe\u8ba1\u7684\u4e00\u822c\u6b65\u9aa4<\/p>\n

\u8fd1\u5e74\u6765\uff0c\u5173\u4e8e\u751f\u7269\u7cfb\u7edf\u4e0e\u7eb3\u7c73\u9897\u7c92\u76f8\u4e92\u4f5c\u7528\u7684\u7814\u7a76\u5bf9\u9776\u5411\u764c\u75c7\u7684\u836f\u7269\u8f7d\u4f53\u7684\u5316\u5b66\u8bbe\u8ba1\u63d0\u51fa\u4e86\u65b0\u7684\u6311\u6218\u3002\u8fd9\u4e9b\u65b0\u7684\u7814\u7a76\u8868\u660e\u9897\u7c92\u5c3a\u5bf8\u3001\u5f62\u72b6\u4ee5\u53ca\u8868\u9762\u5316\u5b66\u90fd\u4f1a\u5f71\u54cd\u9897\u7c92\u4e0e\u751f\u547d\u673a\u4f53\u7684\u4f5c\u7528\u3002\u7ed3\u5408\u8fd9\u4e9b\u57fa\u7840\u7814\u7a76\u8ba4\u8bc6\uff0c\u5229\u7528DNA\u7ec4\u88c5\u53d1\u5c55\u7eb3\u7c73\u9897\u7c92\u8d85\u7ed3\u6784\u662f\u8fd1\u6765\u9887\u53d7\u5173\u6ce8\u7684\u65b0\u578b\u8fd0\u8f7d\u7cfb\u7edf\u3002\u7136\u800c\uff0c\u4e3a\u4e86\u7b26\u5408\u4e34\u5e8a\u5e94\u7528\u7684\u8981\u6c42\uff0c\u638c\u63e1\u5982\u4f55\u8c03\u63a7\u8d85\u7ed3\u6784\u4e2d\u7684DNA\u548c\u7eb3\u7c73\u9897\u7c92\u7684\u7ed3\u5408\u6765\u6700\u4f18\u5316\u764c\u75c7\u6cbb\u7597\u6548\u679c\u662f\u5fc5\u987b\u8981\u653b\u514b\u7684\u96be\u9898\u3002<\/p>\n

\u591a\u4f26\u591a\u5927\u5b66\u7684W. C. W. Chan\uff08\u901a\u8baf\u4f5c\u8005\uff09\u6559\u6388\u8bfe\u9898\u7ec4\u7684\u7814\u7a76\u4eba\u5458\u5728\u5148\u524d\u201c\u6838-\u536b\u661f\u201d\u8d85\u7ed3\u6784\u7684\u8bbe\u8ba1\u57fa\u7840\u4e4b\u4e0a\uff0c\u901a\u8fc7\u5149\u70ed\u6fc0\u53d1\u6765\u63a7\u5236\u8fde\u63a5\u94fe\uff08linker\uff09\u7684\u70ed\u5b66\u8db3\u989d\u53d8\u6027\u4ece\u800c\u8fbe\u5230\u8c03\u63a7\u836f\u7269\u91ca\u653e\u901f\u7387\u7684\u76ee\u7684\u3002\u5b9e\u9a8c\u8868\u660e\u8fd9\u79cd\u5149\u70ed\u89e6\u53d1\u5feb\u901f\u91ca\u653e\u7684\u65b9\u6cd5\u6bd4\u65e0\u6fc0\u5149\u5904\u7406\u7684\u6cbb\u7597\u6548\u679c\u9ad8\u51fa2.1\u500d\u3002\u8fd9\u9879\u7814\u7a76\u4e3a\u4ee5DNA-\u7eb3\u7c73\u9897\u7c92\u8d85\u7ed3\u6784\u7ec4\u88c5\u6280\u672f\u4e3a\u57fa\u7840\u7684\u751f\u7269\u533b\u5b66\u5e94\u7528\u63d0\u4f9b\u4e86\u65b0\u7684\u7b56\u7565\u3002<\/p>\n

\u6587\u732e\u94fe\u63a5\uff1a<\/strong>Tuning the Drug Loading and Release of DNA-Assembled Gold-Nanorod Superstructures<\/a>\uff08Adv. Mater.\uff0c2016\uff0cDOI: 10.1002\/adma.201600773\uff09<\/p>\n

7\u3001ACS Nano \u591a\u529f\u80fd\u78c1\u6027\u8102\u8d28\u4f53\u7684\u6709\u5e8f\u53ef\u63a7\u91ca\u653e<\/strong><\/p>\n

\"7\"<\/p>\n

\u56fe7 <\/strong>\u529f\u80fd\u5316DDS\u7684\u6709\u5e8f\u63a7\u91ca\u673a\u7406<\/p>\n

\u7eb3\u7c73\u533b\u5b66\u88ab\u8ba4\u4e3a\u662f\u5b9e\u73b0\u65e9\u671f\u4e2a\u4f53\u8bca\u65ad\u548c\u7cbe\u51c6\u6cbb\u7597\u7684\u6280\u672f\u7684\u5e0c\u671b\u3002\u5982\u4f55\u5b9e\u73b0\u591a\u79cd\u6cbb\u7597\u5242\u6d3b\u6027\u6210\u5206\u7684\u540c\u65f6\u6216\u8005\u6709\u5e8f\u4f20\u9012\u662f\u7eb3\u7c73\u533b\u5b66\u9886\u57df\u7684\u4e3b\u8981\u6311\u6218\u4e4b\u4e00\u3002\u514b\u670d\u8fd9\u4e00\u6311\u6218\u9700\u8981\u6784\u5efa\u548c\u8bbe\u8ba1\u590d\u6742\u7684\u5668\u4ef6\u548c\u7cfb\u7edf\u3002\u591a\u79cd\u529f\u80fd\u590d\u5408\u7684\u8d85\u5206\u5b50\u81ea\u7ec4\u88c5\u5408\u6210\u65b9\u6cd5\u7b80\u5355\u6613\u884c\uff0c\u7ed3\u6784\u8c03\u63a7\u80fd\u529b\u7a81\u51fa\uff0c\u662f\u7406\u60f3\u7684\u836f\u7269\u8fd0\u8f93\u7cfb\u7edf\uff08DDS\uff09\u3002<\/p>\n

\u4f5b\u7f57\u4f26\u8428\u5927\u5b66\u7684D. Berti\u6559\u6388\uff08\u901a\u8baf\u4f5c\u8005\uff09\u56e2\u961f\u901a\u8fc7\u7b80\u5355\u7684\u81ea\u7ec4\u88c5\u65b9\u6cd5\u6784\u5efa\u4e86\u5177\u6709\u8102\u8d28\/DNA\/\u8d85\u987a\u78c1\u7eb3\u7c73\u9897\u7c92\u7eb3\u7c73\u7ed3\u6784\u5316\u6784\u9020\u7684\u836f\u7269\u8fd0\u8f93\u7cfb\u7edf\u3002\u8fd9\u4e2a\u7cfb\u7edf\u5305\u62ec\u8102\u8d28\u4f53\u652f\u67b6\u4ee5\u53caDNA\u62c9\u94fe\uff08DNA zipper\uff09\u4e24\u79cd\u8f7d\u4f53\uff0c\u53e6\u5916\u8fd8\u6709\u4e24\u79cd\u4f4d\u7f6e\u4e0d\u540c\u7684\u78c1\u6027\u7eb3\u7c73\u9897\u7c92\u4f5c\u4e3a\u78c1\u9a71\u52a8\u91ca\u653e\u7684\u89e6\u53d1\u5668\u3002\u8fd9\u79cd\u7cfb\u7edf\u6700\u5927\u7684\u7279\u70b9\u662f\u901a\u8fc7\u6539\u53d8\u4ea4\u53d8\u78c1\u573a\u7684\u9891\u7387\u53ef\u4ee5\u5b9e\u73b0\u6cbb\u7597\u6027\u5be1\u6838\u82f7\u9178\uff08therapeutic oligonucleotide\uff09\u6216\u8005\u836f\u7269\u7684\u6709\u5e8f\u91ca\u653e\u3002\u5728\u8be5\u9879\u5de5\u4f5c\u4e2d\uff0c\u78c1\u6027\u7eb3\u7c73\u9897\u7c92\u5728\u4f4e\u9891\u4ea4\u6d41\u7535\u573a\u4e2d\u7684\u6709\u6548\u63a7\u91ca\u5df2\u7ecf\u88ab\u6210\u529f\u8bc1\u660e\u3002\u4f46\u662f\u7814\u7a76\u4eba\u5458\u4f9d\u7136\u9700\u8981\u540e\u7eed\u7684\u8840\u6e05\u4ee5\u53ca\u6d3b\u4f53\u5b9e\u9a8c\u6765\u68c0\u6d4b\u8fd9\u79cd\u7cfb\u7edf\u7684\u7a33\u5b9a\u6027\u548c\u91ca\u653e\u7279\u6027\u3002<\/p>\n

\u6587\u732e\u94fe\u63a5\uff1a<\/strong>Multifunctional Magnetoliposomes for Sequential Controlled Release<\/a>\uff08ACS Nano\uff0c2016\uff0cDOI: 10.1021\/acsnano.6b03194\uff09<\/p>\n

8\u3001Adv. Mater. \u7ea2\u8272\u8367\u5149\u56e2\u6709\u673a\u7eb3\u7c73\u5fae\u9897\u7c92\u7528\u6765\u8bc4\u4f30\u8840\u8111\u5c4f\u969c\u7684\u635f\u574f\u7a0b\u5ea6<\/strong><\/p>\n

\"\u56fe\u72478\"
\n\u56fe8\u00a0<\/strong>\u4e0d\u540c\u5c3a\u5bf8\u9897\u7c92\u52a0\u5165TPETPAFN\u7684\u52a8\u6001\u5149\u6563\u5c04\u7ed3\u679c\uff08A:60nm B:30nm C:10nm\uff09<\/p>\n

\u8840\u8111\u5c4f\u969c\uff08BBB\uff09\u4f5c\u4e3a\u5927\u8111\u8109\u7ba1\u7684\u4e00\u4e2a\u7cfb\u7edf\uff0c\u8d1f\u8d23\u7cbe\u786e\u5730\u7ba1\u7406\u5916\u6765\u7ec6\u80de\u6e17\u900f\u800c\u4e14\u662f\u8840\u6e90\u6027\u7269\u8d28\u8fdb\u5165\u5927\u8111\u7684\u5fc5\u7ecf\u4e4b\u8def\uff0c\u5b83\u7684\u7834\u88c2\u7a0b\u5ea6\u76f4\u63a5\u5f71\u54cd\u4e2d\u67a2\u795e\u7ecf\u7684\u635f\u574f\u7a0b\u5ea6\uff0c\u56e0\u6b64\u5176\u5b8c\u6574\u6027\u5bf9\u8111\u635f\u4f24\u6cbb\u7597\u4e2d\u7684\u8bc4\u4f30\u81f3\u5173\u91cd\u8981\u3002\u4f0a\u6587\u6c0f\u84dd\u6cd5\u76ee\u524d\u5728\u8111\u635f\u4f24\u4e2d\u5e7f\u6cdb\u5e94\u7528\uff0c\u4f46\u662f\u7531\u4e8e\u5176\u5b58\u5728\u6709\u5267\u6bd2\u4ee5\u53ca\u5728\u5b9a\u91cf\u8bc4\u4f30\u4e2d\u4e0d\u7a33\u5b9a\u7b49\u9650\u5236\uff0c\u7ed3\u679c\u8fd8\u662f\u5dee\u5f3a\u4eba\u610f\u3002<\/p>\n

\u8fd1\u65e5\uff0c\u6765\u81ea\u65b0\u52a0\u5761\u56fd\u7acb\u5927\u5b66\u7684Bin Liu\uff08\u901a\u8baf\u4f5c\u8005\uff09\u548cLun-De Liao\uff08\u901a\u8baf\u4f5c\u8005\uff09\u7b49\u4eba\u7814\u53d1\u51fa\u53ef\u8c03\u5c3a\u5bf8\u7684\u5e76\u4e14\u80fd\u805a\u96c6\u5f15\u5bfc\u53d1\u5149\u7684\u7ea2\u8272\u8367\u5149\u56e2\u6709\u673a\u5fae\u9897\u7c92\u7528\u4e8e\u8840\u8111\u5c4f\u969c\u635f\u4f24\u7684\u8bc4\u4f30\u3002\u5b9e\u9a8c\u4e2d\u4ed6\u4eec\u628aTPETPAFN\u5316\u5b66\u8bd5\u5242\u52a0\u5165\u5230AIEgens\uff08\u5177\u6709\u805a\u96c6\u8bf1\u53d8\u53d1\u5149\u7279\u6027\u7684\u8367\u5149\u56e2\uff09\u4f7f\u4e4b\u53d8\u6210\u7ea2\u8272\uff0c\u5e76\u5c06\u8367\u5149\u56e2\u9897\u7c92\u63a7\u5236\u621030nm\uff0c60nm\uff0c10nm\u4e09\u7ec4\uff0c\u5728BBB\u635f\u4f24\u7684\u6a21\u578b\u4e0a\u8fdb\u884c\u6d4b\u8bd5\uff0c\u7ed3\u679c\u5728\u5927\u8111\u7684\u4e0d\u540c\u4f4d\u7f6e\u90fd\u53ef\u4ee5\u68c0\u6d4b\u5230BBB\u7684\u635f\u4f24\uff0c\u8fbe\u5230\u4e86\u9884\u671f\u7684\u76ee\u7684\u3002<\/p>\n

\u6587\u732e\u94fe\u63a5\uff1a<\/strong>Biocompatible Red Fluorescent Organic Nanoparticles with Tunable Size and Aggregation-Induced Emission for Evaluation of Blood-Brain Barrier Damage<\/a>\uff08Adv. Mater.\uff0c2016\uff0cDOI: 10.1002\/adma.201601191\uff09<\/p>\n

9\u3001Angew. Chem. Int. Ed. \u4e0a\u8f6c\u6362\u7eb3\u7c73\u7c92\u5b50\u89e3\u51b3\u6d3b\u7ec6\u80de\u5185\u86cb\u767d\u8d28\u7684\u76f8\u4e92\u5f71\u54cd<\/strong><\/p>\n

\"9\"<\/p>\n

\u56fe9 <\/strong>\u9567\u7cfb\u5143\u7d20\u5171\u632f\u80fd\u91cf\u8f6c\u79fb\u7cfb\u7edf\uff08LRET\uff09\u7684\u8bbe\u8ba1\u65b9\u7565<\/p>\n

\u4e0a\u8f6c\u6362\u7eb3\u7c73\u7c92\u5b50\uff08UCNP\uff09\u628a\u8fd1\u7ea2\u5916\uff08NIR\uff09\u8f6c\u53d8\u6210\u53ef\u89c1\u5149\u76f8\u5bf9\u4e8e\u4f7f\u7528\u4f20\u7edf\u7684\u4e24\u76f8\u5438\u6536\u663e\u5fae\u955c\u9700\u8981\u66f4\u4f4e\u7684\u6fc0\u53d1\u5bc6\u5ea6\u3002\u4f46\u662f\u7531\u4e8e\u6676\u683c\u7f3a\u9677\u4ee5\u53ca\u80fd\u529b\u8f6c\u79fb\u5f15\u8d77\u7684\u80fd\u529b\u635f\u5931\u5bfc\u81f4\u91cf\u5b50\u4ea7\u51fa\u4e0d\u8db3\u662fUCNP\u7684\u4e00\u5927\u9650\u5236\u3002<\/p>\n

\u8fd1\u65e5\uff0c\u6765\u81ea\u5fb7\u56fd\u5965\u65af\u7eb3\u5e03\u5415\u514b\u5927\u5b66\u7684Markus Haase\uff08\u901a\u8baf\u4f5c\u8005\uff09\u548cJacob Piehler\uff08\u901a\u8baf\u4f5c\u8005\uff09\u7b49\u4eba\u7814\u53d1\u51fa\u4e86\u9567\u7cfb\u5143\u7d20\u5171\u632f\u80fd\u91cf\u8f6c\u79fb\uff08LRET\uff09\u7cfb\u7edf\u3002\u4ed6\u4eec\u5c06\u5c0f\u4e8e50nm\u7684UCNPs\u4f5c\u4e3aLRET\u5bbf\u4e3b\u5728\u6d3b\u4f53\u7ec6\u80de\u4e0a\uff0c\u901a\u8fc7\u4f18\u5316\u63ba\u6742\u6d53\u5ea6\u548c\u6838\u58f3\u7ed3\u6784\u6765\u83b7\u53d6\u9ad8\u7684\u6fc0\u53d1\u5bc6\u5ea6\uff0c\u7ed3\u679c\u53d1\u73b0\u63d0\u9ad8UCNP\u7684\u91ca\u653e\u4f1a\u589e\u52a0\u7075\u654f\u7684\u53d7\u4f53\u8367\u5149\u56e2\uff0c\u5b9e\u73b0\u4e86\u5728\u6d3b\u4f53\u7ec6\u80de\u901a\u8fc7LRET\u68c0\u6d4b\u86cb\u767d\u8d28\u7684\u76f8\u4e92\u5173\u7cfb\u3002<\/p>\n

\u6587\u732e\u94fe\u63a5\uff1a<\/strong>Engineered Upconversion Nanoparticles for Resolving Protein Interactions inside Living Cells<\/a>\uff08Angew. Chem. Int. Ed.\uff0c 2016\uff0cDOI:10.1002\/anie.201603028\uff09<\/p>\n

10\u3001Nano Lett. \u5fae\u6d41\u4f53\u751f\u4ea7\u7684\u80f6\u539f\u86cb\u767d\u7ea4\u7ef4\u5c55\u73b0\u4f18\u5f02\u7684\u673a\u68b0\u6027\u80fd<\/strong><\/p>\n

\"\u56fe\u724710\"
\n\u56fe10 <\/strong>\u5fae\u6d41\u4f53\u88c5\u7f6e\u751f\u4ea7\u7ea4\u7ef4\u7684\u6d41\u7a0b<\/p>\n

\u80f6\u539f\u86cb\u767d\u7531\u4e8e\u5b83\u4eec\u7684\u673a\u68b0\u7a33\u5b9a\u6027\u3001\u751f\u7269\u53ef\u964d\u89e3\u6027\u548c\u751f\u7269\u76f8\u5bb9\u6027\u5e7f\u6cdb\u7684\u5e94\u7528\u4e8e\u836f\u7269\u8f93\u9001\u4e0e\u7ec4\u7ec7\u5de5\u7a0b\u5b66\uff0c\u901a\u5e38\u4eba\u9020\u7ea4\u7ef4\u662f\u901a\u8fc7\u6e7f\u6cd5\u7eba\u4e1d\u5f97\u5230\u7684\uff0c\u7ea4\u7ef4\u76f4\u5f84\u5927\u4e8e8\u03bcm\uff0c\u8fd9\u79cd\u65b9\u6cd5\u5f97\u5230\u7684\u7ea4\u7ef4\u673a\u68b0\u6027\u80fd\u4e0d\u662f\u5f88\u7406\u60f3\u3002<\/p>\n

\u8fd1\u65e5\uff0c\u6765\u81ea\u5fb7\u56fd\u62dc\u7f57\u4f0a\u7279\u5927\u5b66\u7684Thomas Scheibel\uff08\u901a\u8baf\u4f5c\u8005\uff09\u7b49\u4eba\u4f7f\u7528\u5fae\u6d41\u4f53\u82af\u7247\u88c5\u7f6e\u751f\u4ea7\u51fa\u4e86\u5177\u6709\u4f18\u5f02\u6027\u80fd\u7684\u7ea4\u7ef4\u3002\u5fae\u6d41\u4f53\u88c5\u7f6e\u5c06\u5728\u6570\u5341\u81f3\u6570\u767e\u5fae\u7c73\u8303\u56f4\u901a\u9053\u7684\u6d41\u4f53\u6709\u89c4\u5f8b\u5730\u5d4c\u5165\u5230\u5fae\u5c0f\u82af\u7247\u4e2d\u7ec4\u6210\u805a\u4e8c\u7532\u57fa\u7845\u6c27\u70f7\uff0c\u7528\u6b64\u79cd\u65b9\u6cd5\u4ea7\u51fa\u7684\u7ea4\u7ef4\u76f4\u5f84\u53ea\u67093\u03bcm\u3002\u5728\u5085\u91cc\u53f6\u53d8\u6362\u7ea2\u5916\u5149\u8c31\u4e2d\u663e\u793a\u7ea4\u7ef4\u7684\u53d6\u5411\u6cbf\u7740\u4e2d\u8f74\u7ebf\uff0c\u8fd9\u4f7f\u5f97\u7ea4\u7ef4\u5177\u6709\u975e\u5e38\u68d2\u7684\u673a\u68b0\u7a33\u5b9a\u6027\u80fd\u3002<\/p>\n

\u6587\u732e\u94fe\u63a5\uff1a<\/strong>Microfluidics-Produced Collagen Fibers Show Extraordinary Mechanical Properties<\/a>\uff08Nano Lett.\uff0c2016\uff0cDOI: 10.1021\/acs.nanolett.6b02828\uff09<\/p>\n

11\u3001Adv. Mater. \u53ef\u7528\u4e8e\u5fae\u521b\u624b\u672f\u7684\u8d85\u5206\u5b50\u91d1\u5c5e\u751f\u7269\u9ecf\u5408\u5242<\/strong><\/p>\n

\"\u56fe\u724711\"
\n\u56fe11 <\/strong>\u91d1\u5c5e\u751f\u7269\u9ecf\u5408\u5242\u7528\u4e8e\u5185\u810f\u635f\u4f24\u7684\u4f53\u5185\u4fee\u590d<\/p>\n

\u5c3d\u7ba1\u56fe\u50cf\u5f15\u5bfc\u7684\u4ecb\u5165\u6cbb\u7597\u3001\u5185\u7aa5\u955c\u65b9\u6cd5\u548c\u673a\u5668\u4eba\u624b\u672f\u6280\u672f\u5df2\u53d6\u5f97\u663e\u8457\u8fdb\u5c55\uff0c\u4f46\u662f\u7ee7\u53d1\u4e8e\u708e\u75c7\u6027\u75be\u75c5\u3001\u521b\u4f24\u6216\u624b\u672f\u7684\u6162\u6027\u5668\u5b98\u6e17\u6f0f\u548c\u7618\u7ba1\u4ecd\u7136\u96be\u4ee5\u6cbb\u7597\uff0c\u4f8b\u5982\u80f0\u7618\u3001\u80c6\u9053\u7618\u3001\u80a0\u7618\u3001\u652f\u6c14\u7ba1\u80f8\u819c\u7618\u53ca\u751f\u6b96\u5c3f\u9053\u7618\u7b49\u7b49\u3002\u7618\u7ba1\u4e00\u65e6\u5efa\u7acb\uff0c\u5176\u7597\u7a0b\u6f2b\u957f\u800c\u590d\u6742\uff0c\u4ece\u800c\u589e\u52a0\u4e86\u60a3\u8005\u7684\u7ecf\u6d4e\u8d1f\u62c5\u3002\u7531\u4e8e\u91cd\u590d\u624b\u672f\u4fb5\u5165\u6027\u5f3a\u800c\u4e14\u6548\u679c\u4e0d\u4f73\uff0c\u56e0\u6b64\u9700\u8981\u53d1\u5c55\u65b0\u7684\u66ff\u4ee3\u65b9\u6cd5\u3002\u5177\u6709\u9ecf\u7ed3\u6027\u7684\u7ec4\u7ec7\u5bc6\u5c01\u80f6\u5728\u56fe\u50cf\u5f15\u5bfc\u7684\u4ecb\u5165\u6cbb\u7597\u4e2d\u6709\u6f5c\u529b\u53d1\u6325\u91cd\u8981\u7684\u6cbb\u7597\u4f5c\u7528\uff0c\u4f46\u73b0\u6709\u7684\u6750\u6599\u8fd8\u4e0d\u591f\u7406\u60f3\u3002\u4f8b\u5982\uff0c\u76ee\u524d\u53ef\u7528\u4e8e\u6cbb\u7597\u7618\u7ba1\u7684\u9ecf\u5408\u5242\u6210\u529f\u7387\u53ea\u670960%\uff5e75%\u3002<\/p>\n

\u7f8e\u56fd\u9ebb\u7701\u603b\u533b\u9662\uff08Massachusetts General Hospital\uff09\u7684Ralph Weissleder\uff08\u901a\u8baf\u4f5c\u8005\uff09\u7b49\u4eba\u7814\u53d1\u4e86\u4e00\u79cd\u65b0\u578b\u7684\u91d1\u5c5e\u751f\u7269\u9ecf\u5408\u5242\uff0c\u53ef\u7528\u4f5c\u5fae\u521b\u624b\u672f\u7684\u7ec4\u7ec7\u5bc6\u5c01\u80f6\u3002\u91d1\u5c5e\u7edc\u5408\u4f5c\u7528\u53ef\u4f7f\u660e\u80f6\u884d\u751f\u7269\u4ea7\u751f\u9ecf\u7ed3\u6027\uff0c\u8fd9\u4e2a\u8fc7\u7a0b\u53d1\u751f\u5728\u51e0\u5206\u949f\u5185\uff0c\u9ecf\u5408\u6548\u7387\u9ad8\uff0c\u5e76\u53ef\u5728\u51e0\u4e2a\u661f\u671f\u5185\u5b8c\u5168\u751f\u7269\u964d\u89e3\u3002<\/p>\n

\u6587\u732e\u94fe\u63a5\uff1aSupramolecular Metallo-Bioadhesive for Minimally Invasive Use <\/a>(Adv. Mater.\uff0c2016\uff0cDOI: 10.1002\/adma.201602606\uff09<\/p>\n

12\u3001Nat. Nanotech. \u4e00\u7ef4DNA\u51dd\u805a<\/strong><\/p>\n

\"\u56fe\u724712\"
\n\u56fe12 <\/strong>\u7eb3\u7c73\u675f\u7684\u7ec4\u88c5\u548c\u7ed3\u6784<\/p>\n

DNA\u53ef\u4ee5\u6309\u7167\u7a0b\u5e8f\u5728\u7eb3\u7c73\u5c3a\u5ea6\u7ec4\u88c5\u6210\u5404\u79cd\u5f62\u72b6\u548c\u56fe\u6848\uff0c\u5e76\u53ef\u4f5c\u4e3a\u6df7\u5408\u7eb3\u7c73\u7ed3\u6784\u7684\u6a21\u677f\uff0c\u5982\u5bfc\u7ebf\u3001\u86cb\u767d\u8d28\u9635\u5217\u548c\u573a\u6548\u5e94\u6676\u4f53\u7ba1\u7b49\u3002\u76ee\u524d\u7684DNA\u7eb3\u7c73\u7ed3\u6784\u53d7\u5230\u5e8f\u5217\u7a7a\u95f4\u548c\u7ec4\u5408\u94fe\u957f\u5ea6\u7684\u9650\u5236\uff0c\u901a\u5e38\u662f\u5728\u4e9a\u5fae\u7c73\u8303\u56f4\u5185\u3002<\/p>\n

\u6700\u8fd1\uff0c \u6155\u5c3c\u9ed1\u5de5\u4e1a\u5927\u5b66\u7684 Friedrich C. Simmel\uff08\u901a\u8baf\u4f5c\u8005\uff09\u548c\u4ee5\u8272\u5217\u9b4f\u8328\u66fc\u79d1\u5b66\u7814\u7a76\u6240\u7684 Roy H. Bar-Ziv\uff08\u901a\u8baf\u4f5c\u8005\uff09\u7b49\u4eba\u5728\u4e00\u4e2a\u56fe\u6848\u5316\u7684\u751f\u7269\u82af\u7247\u4e0a\uff0cDNA\u94fe\u6298\u53e0\u6210\u7ea620nm\u5bbd\u300170\u03bcm\u957f\u7684\u4e00\u7ef4\uff081D\uff09\u7ea4\u7ef4\uff0c\u6bcf\u6761\u7ea4\u7ef4\u7684\u6a2a\u622a\u9762\u4e0a\u5305\u542b\u7ea635\u6761\u6392\u5217\u6574\u9f50\u7684\u94fe\u3002\u5728\u5149\u88c2\u89e3\u7684\u5355\u5c42\u4e0a\u5199\u5165\u7684\u7535\u5b50\u675f\u88ab\u7528\u6765\u56fa\u5b9aDNA\u5206\u5b50\u5e76\u4f7f\u5176\u5f62\u6210\u56fe\u6848\uff0cDNA\u5206\u5b50\u5728\u4e9a\u7cbe\u80fa\u5b58\u5728\u65f6\u4f1a\u51dd\u805a\u62101D\u7eb3\u7c73\u675f\u3002DNA\u51dd\u805a\u53ef\u4ee5\u6269\u6563\uff0c\u5e76\u5728\u8054\u7ed3\u70b9\u3001\u4ea4\u53c9\u7f1d\u5904\u65ad\u88c2\u3002\u8be5\u7cfb\u7edf\u9002\u7528\u4e8e\u89e3\u51b3\u6982\u7387\u95ee\u9898\uff0c\u5e76\u88ab\u7528\u6765\u5bfb\u627e\u901a\u8fc7\u8ff7\u5bab\u7684\u53ef\u80fd\u8def\u5f84\u548c\u8bc4\u4f30\u968f\u673a\u5f00\u5173\u7535\u8def\u3002\u8fd9\u9879\u6280\u672f\u4e0e\u7279\u5f02\u5e8f\u5217\u7684DNA\u7eb3\u7c73\u6280\u672f\u7ed3\u5408\uff0c\u53ef\u4ee5\u7528\u6765\u4f20\u64ad\u751f\u7269\u6216\u79bb\u5b50\u4fe1\u53f7\uff0c\u6216\u7528\u6765\u8c03\u8282\u65e0\u7ec6\u80deDNA\u533a\u57df\u7684\u57fa\u56e0\u8868\u8fbe\u3002<\/p>\n

\u6587\u732e\u94fe\u63a5\uff1a<\/strong>DNA condensation in one dimension<\/a>\u00a0\uff08Nat. Nanotech.\uff0c2016\uff0cDOI: 10.1038\/nnano.2016.142\uff09<\/p>\n

\u672c\u6587\u7531\u6750\u6599\u4eba\u751f\u7269\u6750\u6599\u5b66\u4e60\u5c0f\u7ec4\u9648\u4e16\u96c4\u3001\u9c81\u5065\u3001\u674e\u4f26\u3001\u9648\u662d\u94ed\u4f9b\u7a3f\uff0c\u6750\u6599\u725b\u7f16\u8f91\u6574\u7406\u3002<\/p>\n

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