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MacMillan\uff08\u901a\u8baf\u4f5c\u8005\uff09\u6559\u6388\u56e2\u961f\u9996\u6b21\u8bc1\u660e\u4e86\u53ef\u4ee5\u4f7f\u7528\u7b80\u5355\u7684\u7fa7\u9178\u5206\u5b50\u548c\u70f7\u70c3\u7c7b\u5206\u5b50\u5206\u522b\u4f5c\u4e3a\u4eb2\u6838\u2014\u2014\u4eb2\u7535\u8026\u5408\u5bf9\uff0c\u5229\u7528\u954d\u50ac\u5316\u8fd8\u539f\u5242\u7684\u534f\u540c\u5408\u5e76\u4f5c\u7528\u5b9e\u73b0sp<sup>3<\/sup>-sp<sup>3<\/sup>\u952e\u7684\u76f4\u63a5\u5f62\u6210\u3002\u800c\u8fd9\u9879\u8026\u5408\u65b9\u6cd5\u7684\u4f18\u70b9\u4e4b\u4e00\u4fbf\u5728\u4e8e\u80fd\u591f\u4ece\u7b80\u5355\u7684\u8d77\u59cb\u7269\u51fa\u53d1\u53ea\u9700\u56db\u6b65\u5c31\u53ef\u4ee5\u5408\u6210\u836f\u7269\u66ff\u7f57\u975e\u73ed\u3002<\/p>\n<p><strong>\u56fe\u6587\u5bfc\u8bfb\uff1a<\/strong><\/p>\n<p><strong>\u56fe<\/strong><strong>1<\/strong><strong>\uff1a\u91d1\u5c5e\u5149\u50ac\u5316\u5242\u4ecb\u8d28\u50ac\u5316\u4f5c\u4e3a\u8026\u5408\u5bf9\u7684\u7fa7\u9178\u5206\u5b50\u5f62\u6210<\/strong><strong>sp<sup>3<\/sup>-sp<sup>3<\/sup><\/strong><strong>\u952e\u7684\u8fc7\u7a0b<\/strong><\/p>\n<p style=\"text-align: center;\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-34680\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2016\/08\/01-1.jpg\" alt=\"01\" width=\"500\" height=\"396\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2016\/08\/01-1.jpg 500w, \/\/m.iemloyee.com\/wp-content\/uploads\/2016\/08\/01-1-300x238.jpg 300w\" sizes=\"(max-width: 500px) 100vw, 500px\" 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decoding=\"async\" class=\"alignnone size-full wp-image-34683\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2016\/08\/02-1.jpg\" alt=\"02\" width=\"500\" height=\"473\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2016\/08\/02-1.jpg 500w, \/\/m.iemloyee.com\/wp-content\/uploads\/2016\/08\/02-1-300x284.jpg 300w\" sizes=\"(max-width: 500px) 100vw, 500px\" 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style=\"text-align: center;\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-34684\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2016\/08\/03-a.jpg\" alt=\"03-a\" width=\"500\" height=\"88\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2016\/08\/03-a.jpg 500w, \/\/m.iemloyee.com\/wp-content\/uploads\/2016\/08\/03-a-300x53.jpg 300w\" sizes=\"(max-width: 500px) 100vw, 500px\" \/> <img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-34685\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2016\/08\/03-b.jpg\" alt=\"03-b\" width=\"499\" height=\"228\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2016\/08\/03-b.jpg 499w, \/\/m.iemloyee.com\/wp-content\/uploads\/2016\/08\/03-b-300x137.jpg 300w\" sizes=\"(max-width: 499px) 100vw, 499px\" \/> <img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-34686\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2016\/08\/03-cd.jpg\" alt=\"03-cd\" width=\"500\" height=\"157\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2016\/08\/03-cd.jpg 500w, \/\/m.iemloyee.com\/wp-content\/uploads\/2016\/08\/03-cd-300x94.jpg 300w\" sizes=\"(max-width: 500px) 100vw, 500px\" \/><\/p>\n<p>a\uff0c\u603b\u53cd\u5e94\u8fc7\u7a0b\uff1b<\/p>\n<p>b-d\uff0c\u5e95\u7269\u4e0e\u76f8\u5173\u53c2\u6570\u3002<\/p>\n<p><strong>\u56fe<\/strong><strong>4<\/strong><strong>\uff1a\u4e24\u79cd\u4e0d\u540c\u7684\u8fc7\u6e21\u91d1\u5c5e\u5149\u50ac\u5316\u5242\u65b9\u6848\u5206\u522b\u5728\u5408\u6210\u836f\u7269\u66ff\u7f57\u975e\u73ed\u4e2d\u7684\u5e94\u7528<\/strong><\/p>\n<p style=\"text-align: center;\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-34687\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2016\/08\/04-1.jpg\" alt=\"04\" width=\"500\" height=\"280\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2016\/08\/04-1.jpg 500w, \/\/m.iemloyee.com\/wp-content\/uploads\/2016\/08\/04-1-300x168.jpg 300w\" sizes=\"(max-width: 500px) 100vw, 500px\" \/><\/p>\n<p>1\uff0c\u4f7f\u7528Ni\u548cIr\u50ac\u5316\u7fa7\u9178\uff0842\uff09\u548c\u5364\u4ee3\u70f7\uff0843\uff09\u50ac\u5316\u5f62\u6210\u65b0\u578b\u7684sp<sup>3<\/sup>-sp<sup>3<\/sup>\u952e\uff0c\u968f\u540e\u7684\u56db\u4e01\u57fa\u6c1f\u5316\u94f5\uff08TBAF\uff09\u63d0\u4f9b\u9152\u7cbe\uff0844\uff09\uff1b<\/p>\n<p>2\uff0c\u66ff\u7f57\u975e\u73ed\uff0845\uff09\u5728\u4e4b\u540e\u7684\u4e24\u6b65\u4e2d\u88ab\u5408\u6210\uff0c\u901a\u8fc7Ni\/Ir\u7684\u50ac\u5316\u53d1\u751f\u919a\u5316\u53cd\u5e94\u548c\u8131\u9178\u6027\u53cd\u5e94\uff0c\u6700\u7ec834%\u7684\u6eb4\u8d77\u59cb\u7269\u6599\u88ab\u56de\u6536\u3002<\/p>\n<p><strong>\u6587\u732e\u94fe\u63a5\uff1a<\/strong><a href=\"http:\/\/www.nature.com\/nature\/journal\/v536\/n7616\/full\/nature19056.html\" target=\"_blank\">Metallaphotoredox-catalysed sp<sup>3<\/sup>\u2013sp<sup>3<\/sup> cross-coupling of carboxylic acids with alkyl halides<\/a> \uff08Nature\uff0c 2016\uff0cDOI: 10.1038\/nature19056\uff09<\/p>\n<p>\u8be5\u6587\u732e\u5bfc\u8bfb\u7531\u6750\u6599\u4eba\u65b0\u80fd\u6e90\u5b66\u672f\u5c0f\u7ec4Carbon\u4f9b\u7a3f\uff0c\u6750\u6599\u725b\u7f51\u4e13\u6ce8\u4e8e\u8ddf\u8e2a\u6750\u6599\u9886\u57df\u79d1\u6280\u53ca\u884c\u4e1a\u8fdb\u5c55\uff0c\u8fd9\u91cc\u6c47\u96c6\u4e86\u5404\u5927\u9ad8\u6821\u7855\u535a\u751f\u3001\u4e00\u7ebf\u79d1\u7814\u4eba\u5458\u4ee5\u53ca\u884c\u4e1a\u4ece\u4e1a\u8005\uff0c\u5982\u679c\u60a8\u5bf9\u4e8e\u8ddf\u8e2a\u6750\u6599\u9886\u57df\u79d1\u6280\u8fdb\u5c55\uff0c\u89e3\u8bfb\u9ad8\u6c34\u5e73\u6587\u7ae0\u6216\u662f\u8bc4\u8ff0\u884c\u4e1a\u6709\u5174\u8da3\uff0c<a href=\"\/\/m.iemloyee.com\/25127.html\" target=\"_blank\">\u70b9\u6211\u52a0\u5165\u7f16\u8f91\u90e8<\/a>\u3002<\/p>\n<p><a href=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2016\/08\/\u6750\u6599\u4eba.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-34901\" 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