{"id":265756,"date":"2025-03-27T09:14:51","date_gmt":"2025-03-27T01:14:51","guid":{"rendered":"\/\/m.iemloyee.com\/?p=265756"},"modified":"2025-03-27T09:14:51","modified_gmt":"2025-03-27T01:14:51","slug":"%e4%bb%8a%e6%97%a5nature%ef%bc%9a%e5%8f%98%e5%ba%9f%e4%b8%ba%e5%ae%9d%ef%bc%8c%e6%a9%a1%e8%83%b6%e5%9b%9e%e6%94%b6%e6%96%b0%e6%8a%80%e6%9c%af%ef%bc%81","status":"publish","type":"post","link":"\/\/m.iemloyee.com\/?p=265756","title":{"rendered":"\u4eca\u65e5Nature\uff1a\u53d8\u5e9f\u4e3a\u5b9d\uff0c\u6a61\u80f6\u56de\u6536\u65b0\u6280\u672f\uff01"},"content":{"rendered":"<p><strong>\u4e00\u3001\u3010\u79d1\u5b66\u80cc\u666f\u3011<\/strong><\/p>\n<p>\u5168\u7403\u6bcf\u5e74\u4ea7\u751f\u5927\u91cf\u5e9f\u5f03\u8f6e\u80ce\uff0c\u4ec5\u7f8e\u56fd2021\u5e74\u5c31\u67092.74\u4ebf\u6761\u8f6e\u80ce\u88ab\u5e9f\u5f03\uff0c\u5176\u4e2d17%\u88ab\u586b\u57cb\u5904\u7406\uff0c\u4e0d\u4ec5\u5360\u7528\u5927\u91cf\u7a7a\u95f4\uff0c\u8fd8\u5b58\u5728\u5316\u5b66\u6d78\u51fa\u3001\u81ea\u71c3\u7b49\u95ee\u9898\u3002\u4f20\u7edf\u70ed\u89e3\u6cd5\u867d\u80fd\u56de\u6536\u90e8\u5206\u6750\u6599\uff0c\u4f46\u4f1a\u91ca\u653e\u82ef\u3001\u4e8c\u5641\u82f1\u7b49\u6709\u5bb3\u526f\u4ea7\u7269\u3002\u73b0\u6709\u5316\u5b66\u56de\u6536\u65b9\u6cd5\uff08\u5982\u8131\u786b\u6216\u4e3b\u94fe\u88c2\u89e3\uff09\u5b58\u5728\u6548\u7387\u4f4e\u3001\u4ea7\u7269\u4ef7\u503c\u4f4e\u6216\u4f9d\u8d56\u6602\u8d35\u50ac\u5316\u5242\u7b49\u95ee\u9898\u3002\u56e0\u6b64\uff0c\u4e9f\u9700\u5f00\u53d1\u9ad8\u6548\u3001\u73af\u4fdd\u7684\u6a61\u80f6\u5316\u5b66\u56de\u6536\u6280\u672f\u3002<\/p>\n<p><strong>\u4e8c\u3001\u3010\u521b\u65b0\u6210\u679c\u3011<\/strong><\/p>\n<p>\u8fd1\u671f\uff0c<strong>\u7f8e\u56fd\u5317\u5361\u7f57\u6765\u7eb3\u5927\u5b66\u6559\u5802\u5c71\u5206\u6821<\/strong><strong>Aleksandr V. Zhukhovitskiy<\/strong><strong>\u6559\u6388<\/strong>\u56e2\u961f\u5728<strong><em>Nature<\/em><\/strong>\u4e0a\u53d1\u8868\u4e86\u9898\u4e3a\u201c<strong>Deconstruction of rubber via C\u2013H amination and aza-Cope rearrangement<\/strong>\u201d\u7684\u8bba\u6587\uff0c\u62a5\u9053\u4e86\u4e00\u79cd\u5e94\u7528\u805a\u5408\u7269\u7684 C-H \u6c28\u5316\u548c\u9aa8\u67b6\u91cd\u6392\u5c06\u8f6e\u80ce\u4e2d\u4e8c\u70ef\u805a\u5408\u7269\u89e3\u6784\u4e3a\u73af\u6c27\u6811\u8102\u7684\u524d\u4f53\u7684\u7b56\u7565\u3002\u5177\u4f53\u5730\uff0c\u7814\u7a76\u4eba\u5458\u4f7f\u7528\u4e00\u79cd\u786b\u4e8c\u4e9a\u80fa\u8bd5\u5242\u8bd5\u5242\uff0c\u53ef\u4f7f\u4e8c\u70ef\u805a\u5408\u7269\u548c\u6a61\u80f6\u7684\u70ef\u4e19\u57fa\u80fa\u5316\u7387\u9ad8\u8fbe 35%\u3002\u7136\u540e\u5e94\u7528\u9633\u79bb\u5b50 2-aza-Cope \u91cd\u6392\uff08ACR\uff09\u6765\u89e3\u6784\u80fa\u5316\u4e8c\u70ef\u805a\u5408\u7269\u3002\u5b9e\u9a8c\u7ed3\u679c\u8868\u660e\uff0c\u5728\u4e00\u4e2a\u6a21\u578b\u4f53\u7cfb\u4e2d\u5206\u5b50\u91cf\u4ece 58,100 g\/mol \u964d\u4f4e\u5230\u5927\u7ea6 400 g\/mol\uff0c\u5e9f\u5f03\u8f6e\u80ce\u6a61\u80f6\u53ef\u4ee5\u57286\u5c0f\u65f6\u5185\u8f6c\u5316\u4e3a\u53ef\u6eb6\u6027\u7684\u80fa\u529f\u80fd\u5316\u805a\u5408\u7269\uff0c\u8fd9\u4e9b\u805a\u5408\u7269\u53ef\u4ee5\u7528\u4e8e\u5236\u5907\u4e0e\u5546\u4e1a\u53cc\u915aA\u884d\u751f\u73af\u6c27\u6811\u8102\u5177\u6709\u76f8\u4f3c\u521a\u6027\u7684\u73af\u6c27\u70ed\u56fa\u6027\u6750\u6599\u3002\u603b\u4e4b\uff0c\u8fd9\u9879\u7814\u7a76\u6210\u679c\u8bc1\u660e\u4e86 C-H \u6c28\u5316\u548c\u9aa8\u67b6\u91cd\u6392\u6280\u672f\u5728\u5b9e\u73b0\u5e9f\u5f03\u5316\u5b66\u54c1\u56de\u6536\u5229\u7528\u65b9\u9762\u7684\u5f3a\u5927\u529f\u80fd\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-265757\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2025\/03\/0-3.png\" alt=\"\" width=\"600\" height=\"303\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2025\/03\/0-3.png 600w, \/\/m.iemloyee.com\/wp-content\/uploads\/2025\/03\/0-3-300x152.png 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/p>\n<p><strong>\u4e09\u3001\u3010\u56fe\u6587\u89e3\u6790\u3011<\/strong><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-265758\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2025\/03\/1-4.png\" alt=\"\" width=\"600\" height=\"264\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2025\/03\/1-4.png 600w, \/\/m.iemloyee.com\/wp-content\/uploads\/2025\/03\/1-4-300x132.png 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/p>\n<p><strong>\u56fe<\/strong><strong>1\u00a0 <\/strong><strong>\u6a61\u80f6\u89e3\u6784\u7b56\u7565\u793a\u610f\u56fe<\/strong><strong> \u00a9 2025 Springer Nature<\/strong><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-265759\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2025\/03\/2-2.png\" alt=\"\" width=\"600\" height=\"456\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2025\/03\/2-2.png 600w, \/\/m.iemloyee.com\/wp-content\/uploads\/2025\/03\/2-2-300x228.png 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/p>\n<p><strong>\u56fe<\/strong><strong>2\u00a0 <\/strong><strong>\u6a21\u578b\u5e95\u7269<\/strong><strong>1<\/strong><strong>\u3001<\/strong><strong>5<\/strong><strong>\u548c<\/strong><strong>9<\/strong><strong>\u4e0a\u7684\u70ef\u4e19\u57fa\u80fa\u5316<\/strong> <strong>\u00a9 2025 Springer Nature<\/strong><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-265760\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2025\/03\/3-3.png\" alt=\"\" width=\"600\" height=\"285\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2025\/03\/3-3.png 600w, \/\/m.iemloyee.com\/wp-content\/uploads\/2025\/03\/3-3-300x143.png 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/p>\n<p><strong>\u56fe<\/strong><strong>3\u00a0 ACR<\/strong><strong>\u89e3\u6784\u7814\u7a76\u7ed3\u679c<\/strong><strong> \u00a9 2025 Springer Nature<\/strong><strong>\u00a0<img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-265761\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2025\/03\/4-3.png\" alt=\"\" width=\"600\" height=\"476\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2025\/03\/4-3.png 600w, \/\/m.iemloyee.com\/wp-content\/uploads\/2025\/03\/4-3-300x238.png 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/strong><\/p>\n<p><strong>\u56fe<\/strong><strong>4\u00a0 <\/strong><strong>\u4ea4\u8054\u6750\u6599\u7684\u89e3\u6784\u4e0e\u4ea7\u54c1\u7684\u5e94\u7528<\/strong><strong> \u00a9 2025 Springer Nature<\/strong><\/p>\n<p>&nbsp;<\/p>\n<p><strong>\u56db\u3001\u3010\u79d1\u5b66\u542f\u8fea\u3011<\/strong><\/p>\n<p>\u7efc\u4e0a\uff0c\u672c\u7814\u7a76\u6210\u529f\u5f00\u53d1\u4e86\u4e00\u79cd\u65b0\u7684\u5316\u5b66\u56de\u6536\u65b9\u6cd5\uff0c\u901a\u8fc7C-H\u6c28\u57fa\u5316\u548cACR\u53cd\u5e94\uff0c\u53ef\u4ee5\u5c06\u5e9f\u5f03\u7684\u4e8c\u70ef\u70c3\u805a\u5408\u7269\u89e3\u6784\u4e3a\u6709\u4ef7\u503c\u7684\u80fa\u529f\u80fd\u5316\u805a\u5408\u7269\u3002\u8fd9\u79cd\u65b9\u6cd5\u4e0d\u4ec5\u9002\u7528\u4e8e\u7ebf\u6027\u805a\u5408\u7269\uff0c\u8fd8\u53ef\u4ee5\u5904\u7406\u4ea4\u8054\u7684\u6a61\u80f6\u6750\u6599\u3002\u4e0e\u4f20\u7edf\u7684\u70ed\u89e3\u65b9\u6cd5\u76f8\u6bd4\uff0c\u8be5\u65b9\u6cd5\u5728\u6e29\u548c\u7684\u6761\u4ef6\u4e0b\u8fdb\u884c\uff0c\u4e0d\u4ea7\u751f\u6709\u5bb3\u526f\u4ea7\u54c1\uff0c\u4e14\u4e0d\u4f9d\u8d56\u4e8e\u6602\u8d35\u7684\u91d1\u5c5e\u50ac\u5316\u5242\u3002\u6b64\u5916\uff0c\u89e3\u6784\u540e\u7684\u805a\u5408\u7269\u53ef\u4ee5\u4f5c\u4e3a\u73af\u6c27\u6811\u8102\u7684\u56fa\u5316\u5242\uff0c\u5177\u6709\u6f5c\u5728\u7684\u9ad8\u9644\u52a0\u503c\u5e94\u7528\u3002\u5c3d\u7ba1\u8be5\u65b9\u6cd5\u5728\u5b9e\u9a8c\u5ba4\u4e2d\u53d6\u5f97\u4e86\u6210\u529f\uff0c\u4f46\u5728\u5b9e\u9645\u5e94\u7528\u4e2d\u4ecd\u9700\u89e3\u51b3\u4e00\u4e9b\u6311\u6218\uff0c\u5982\u80fa\u5316\u6548\u7387\uff08~35%\uff09\u548c\u89e3\u6784\u5206\u5b50\u91cf\u5206\u5e03\u9700\u8fdb\u4e00\u6b65\u63d0\u5347\uff1b\u6eb6\u5242\u4f7f\u7528\u91cf\u8f83\u5927\uff0c\u672a\u6765\u53ef\u901a\u8fc7\u8fde\u7eed\u6d41\u53cd\u5e94\u6216\u7eff\u8272\u6eb6\u5242\u4f18\u5316\u964d\u4f4e\u73af\u5883\u56e0\u5b50\uff1b\u5b9e\u9645\u5e9f\u5f03\u6a61\u80f6\u4e2d\u6dfb\u52a0\u5242\u5bf9\u53cd\u5e94\u7684\u5f71\u54cd\u9700\u8fdb\u4e00\u6b65\u7814\u7a76\u7b49\u3002\u603b\u4e4b\uff0c\u8be5\u7814\u7a76\u901a\u8fc7\u521b\u65b0\u6027\u7684\u5316\u5b66\u65b9\u6cd5\u5c06\u5e9f\u5f03\u6a61\u80f6\u8f6c\u5316\u4e3a\u529f\u80fd\u6027\u6750\u6599\uff0c\u4e0d\u4ec5\u89e3\u51b3\u4e86\u73af\u5883\u95ee\u9898\uff0c\u8fd8\u4e3a\u5faa\u73af\u7ecf\u6d4e\u63d0\u4f9b\u4e86\u6280\u672f\u652f\u6491\u3002\u672a\u6765\u9700\u5728\u89c4\u6a21\u5316\u751f\u4ea7\u3001\u6210\u672c\u63a7\u5236\u53ca\u5168\u751f\u547d\u5468\u671f\u5206\u6790\uff08LCA\uff09\u65b9\u9762\u6df1\u5316\u7814\u7a76\uff0c\u4ee5\u63a8\u52a8\u5de5\u4e1a\u5316\u5e94\u7528\u3002<\/p>\n<p>\u539f\u6587\u8be6\u60c5\uff1a<a href=\"https:\/\/www.nature.com\/articles\/s41586-025-08716-6\" target=\"_blank\" rel=\"noopener\">Deconstruction of rubber via C\u2013H amination and aza-Cope rearrangement<\/a> (<em>Nature<\/em> <strong>2025<\/strong>, DOI: 10.1038\/s41586-025-08716-6)<\/p>\n<p>\u672c\u6587\u7531\u8d5b\u6069\u65af\u4f9b\u7a3f\u3002<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u4e00\u3001\u3010\u79d1\u5b66\u80cc\u666f\u3011 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