{"id":257874,"date":"2024-02-15T06:17:28","date_gmt":"2024-02-14T22:17:28","guid":{"rendered":"\/\/m.iemloyee.com\/?p=257874"},"modified":"2024-02-14T21:28:26","modified_gmt":"2024-02-14T13:28:26","slug":"%e6%bb%9a%e7%9f%b3%e7%94%9f%e8%8a%b1%ef%bc%81%e5%8d%97%e4%ba%ac%e5%b7%a5%e4%b8%9a%e5%a4%a7%e5%ad%a6%e9%ab%98%e5%85%b5%e5%85%b5adv-funct-mater-%ef%bc%9a%e5%9f%ba%e4%ba%8e%e6%bb%9a%e5%8a%a8%e5%be%ae","status":"publish","type":"post","link":"\/\/m.iemloyee.com\/?p=257874","title":{"rendered":"\u6eda\u77f3\u751f\u82b1\uff01\u5357\u4eac\u5de5\u4e1a\u5927\u5b66\u9ad8\u5175\u5175Adv. Funct. Mater.\uff1a\u57fa\u4e8e\u6eda\u52a8\u5fae\u9488\u5236\u5907\u4eff\u751f\u8d85\u7ed3\u6784\u7684\u5fae\u6d41\u4f53\u5fae\u9488\u8d34\u7247\u5e76\u7528\u4e8e\u9ad8\u6548\u4f24\u53e3\u7ba1\u7406"},"content":{"rendered":"<p>\u8fd1\u65e5\uff0c\u5357\u4eac\u5de5\u4e1a\u5927\u5b66\u836f\u5b66\u9662\u9ad8\u5175\u5175\u526f\u6559\u6388\u56e2\u961f\u5728\u56fd\u9645\u77e5\u540d\u6750\u6599\u79d1\u5b66\u5b66\u672f\u671f\u520a\u300aAdvanced Functional Materials\u300b\uff08IF=19.00\uff09\u53d1\u8868\u201cRolling Stone Gathers Moss: Rolling Microneedles Generate Meta Microfluidic Microneedles (MMMs)\u201d\u7684\u7814\u7a76\u6210\u679c\uff0c\u8be5\u56e2\u961f\u62a5\u9053\u4e86\u57fa\u4e8e\u6eda\u52a8\u5fae\u9488\u5236\u5907\u4eff\u751f\u8d85\u7ed3\u6784\u5fae\u6d41\u4f53\u5fae\u9488\u82af\u7247\uff08MMMs\uff09\u7528\u4e8e\u9ad8\u6548\u4f24\u53e3\u7ba1\u7406\u7684\u6700\u65b0\u7814\u7a76\u3002\u4f5c\u8005\u91c7\u7528\u5546\u54c1\u5316\u6eda\u52a8\u5fae\u9488\u5b9e\u73b0\u53cc\u9762\u6e17\u900f\u548c\u56fe\u6848\u5316\u8bbe\u8ba1\uff0c\u5b83\u65e2\u80fd\u7528\u4e8e\u5236\u5907\u5fae\u9488\uff0c\u53c8\u53ef\u4ee5\u6784\u5efa\u4e09\u7ef4\u591a\u5c42\u5fae\u6d41\u4f53\u901a\u9053\u3002\u8fd9\u79cd\u5236\u5907\u65b9\u6cd5\u5177\u6709\u5feb\u901f\u7b80\u4fbf\u9ad8\u6548\u7684\u4f18\u52bf\uff0c\u8be5\u751f\u7269\u542f\u53d1\u7684MMMs\u8d34\u7247\u7684\u4e0d\u4ec5\u5728\u4f24\u53e3\u7ba1\u7406\uff0c\u800c\u4e14\u5728\u4e34\u5e8a\u7ed9\u836f\u3001POCT\u7b49\u9886\u57df\u90fd\u5177\u6709\u5de8\u5927\u7684\u53d1\u5c55\u6f5c\u529b\u3002\u5357\u4eac\u5de5\u4e1a\u5927\u5b66\u836f\u5b66\u9662\u7855\u58eb\u4e8c\u5e74\u7ea7\u7814\u7a76\u751f\u5468\u94b1\uff08\u7814\u7a76\u751f\u56fd\u5bb6\u5956\u5b66\u91d1\u83b7\u5f97\u8005\uff09\u4e3a\u7b2c\u4e00\u4f5c\u8005\uff0c\u9ad8\u5175\u5175\u526f\u6559\u6388\u4e3a\u8be5\u8bba\u6587\u7684\u552f\u4e00\u901a\u8baf\u4f5c\u8005\u3002<\/p>\n<p><strong>Part.1\/<\/strong> <strong>\u7814\u7a76\u80cc\u666f<\/strong><strong>:<\/strong><\/p>\n<p>\u5728\u8fc7\u53bb\u7684\u51e0\u5341\u5e74\u4e2d\uff0c\u5fae\u6d41\u4f53\u82af\u7247\u4f5c\u4e3a\u5904\u7406\u5fae\u5c0f\u6db2\u6ef4\u6216\u5c0f\u578b\u6db2\u4f53\u6837\u54c1\u7684\u5c0f\u578b\u5b9e\u9a8c\u5ba4\u8bbe\u5907\uff0c\u5177\u6709\u5feb\u901f\u5206\u6790\u3001\u5c0f\u5bb9\u91cf\u5904\u7406\u548c\u6210\u672c\u6548\u76ca\u9ad8\u7b49\u4f18\u70b9\u3002\u7136\u800c\uff0c\u5fae\u6d41\u4f53\u82af\u7247\u5728\u4e34\u5e8a\u5206\u6790\u9886\u57df\u9762\u4e34\u7740\u8bf8\u591a\u5c40\u9650\u6027\u3002\u4e3a\u4e86\u63d0\u9ad8\u9002\u5e94\u6027\u548c\u96c6\u6210\u5ea6\uff0c\u6709\u5fc5\u8981\u5411\u66f4\u5c0f\u3001\u66f4\u590d\u6742\u7684\u5c3a\u5bf8\u53d1\u5c55\u3002\u73b0\u6709\u7684\u5fae\u6d41\u4f53\u82af\u7247\u7f3a\u4e4f<strong>\u4e09\u7ef4\uff08<\/strong><strong>3D<\/strong><strong>\uff09\u5206\u6790<\/strong>\u80fd\u529b\uff0c\u6025\u9700\u5f00\u53d1\u4e00\u79cd<strong>\u9ad8\u5ea6\u96c6\u6210<\/strong>\u7684<strong>\u8d85\u7ed3\u6784<\/strong>\u5fae\u6d41\u4f53\u82af\u7247\uff0c\u4ee5\u5b9e\u73b0\u591a\u7ef4\u6d41\u4f53\u63a7\u5236\u3002\u8fd1\u5e74\u6765\uff0c\u57fa\u4e8ePC\u819c\u7684\u5206\u6790\u65b9\u6cd5\u56e0\u5176\u5177\u6709\u975e\u63a5\u89e6\u3001<strong>\u53ef\u89c6\u5316<\/strong>\u7684\u4f20\u611f\u7279\u6027\u800c\u5907\u53d7\u5173\u6ce8\uff0c\u5177\u6709\u5c06\u751f\u7269\u5316\u5b66\u4fe1\u53f7\u8f6c\u6362\u6210\u5149\u4fe1\u53f7\u7684\u80fd\u529b\uff0c\u5f53\u5176\u7ed3\u5408\u4e0a\u5fae\u6d41\u4f53\u5fae\u9488\u65f6\uff0c\u53ef\u4ee5\u5b9e\u73b0\u4f24\u53e3\u90e8\u4f4d\u7684\u539f\u4f4d\u76d1\u6d4b\uff0c\u9ad8\u6548\u7ba1\u7406\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-257875\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2024\/02\/1-14.png\" alt=\"\" width=\"600\" height=\"326\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2024\/02\/1-14.png 600w, \/\/m.iemloyee.com\/wp-content\/uploads\/2024\/02\/1-14-300x163.png 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/p>\n<p>\u56fe1. \u8d85\u7ed3\u6784\u5fae\u6d41\u4f53\u5fae\u9488\uff08MMMs\uff09\u7528\u4e8e\u667a\u80fd\u4f24\u53e3\u7ba1\u7406\uff08\u5305\u62ec\u8fd0\u52a8\u4f20\u611f\u3001\u751f\u5316\u5206\u6790\u548c\u4f24\u53e3\u6108\u5408\uff09\u7684\u793a\u610f\u56fe\u3002A.\u5b9e\u9a8c\u4e2d\u4f7f\u7528\u7684\u5546\u54c1\u5316\u6eda\u52a8\u5fae\u9488\u6b63\u9762\uff0c\u4fa7\u9762\u548c\u7ec6\u8282\u56fe\u3002B.\u53d7\u751f\u7269\u542f\u53d1\u76841D,2D\u548c3DPCs\u3002C\u6eda\u52a8\u5fae\u9488\u5236\u5907\u57fa\u4e8ePC\u819c\u7684\u5fae\u6d41\u4f53\u5fae\u9488\u793a\u610f\u56fe\u3002D\u5728\u4f24\u53e3\u6108\u5408\u7684\u5e94\u7528\u793a\u610f\u56fe\u53ca\u591a\u5c42\u7ed3\u6784\u793a\u610f\u56fe\u3002<\/p>\n<p><strong>Part.2\/<\/strong><strong>\u8bbe\u8ba1\u601d\u8def\uff1a<\/strong><\/p>\n<p>\u4f5c\u8005\u63d0\u51fa\u4e86\u5229\u7528\u5546\u54c1\u5316\u7684\u6eda\u52a8\u5fae\u9488\uff08RMNs\uff09\u5728\u819c\u4e0a\u751f\u6210\u8d85\u7ed3\u6784\u6a21\u677f\u7684\u65b9\u6cd5\uff0c\u5236\u5907\u51fa\u591a\u529f\u80fd\u96c6\u6210\u7684\u5fae\u6d41\u4f53\u82af\u7247\uff08MMMs\uff09\uff08\u56fe1\uff09\u3002\u901a\u8fc7\u5728\u6240\u9700\u4f4d\u7f6e\u76f4\u63a5\u4f7f\u7528\u6eda\u52a8\u5fae\u9488\u5b9e\u73b0\u53cc\u9762\u6e17\u900f\u548c\u56fe\u6848\u5316\u8bbe\u8ba1\uff0c\u5b83\u65e2\u80fd\u7528\u4e8e\u5236\u4f5c\u5fae\u9488\uff0c\u53c8\u53ef\u4ee5\u6784\u5efa\u4e09\u7ef4\u591a\u5c42\u5fae\u6d41\u4f53\u901a\u9053\u3002\u5229\u7528\u5236\u4f5c\u51fa\u6765\u7684\u5fae\u6d41\u4f53\u5fae\u9488\u8d34\u7247\u6700\u7ec8\u5b9e\u73b0\u4e86\u5168\u9762\u7684\u4f24\u53e3\u7ba1\u7406\u3002<\/p>\n<p><strong>Part.3\/<\/strong><strong>\u7814\u7a76\u4eae\u70b9\uff1a<\/strong><\/p>\n<p>1.\u6eda\u52a8\u5fae\u9488<\/p>\n<p>\u672c\u6587\u4e2d\u7684\u5fae\u9488\uff08MNs\uff09\u7684\u5236\u5907\u65b9\u5f0f\u4e0e\u4f20\u7edf\u4e0d\u540c\uff0c\u5728\u8fd9\u91cc\u4f7f\u7528\u4e86\u4e00\u79cd\u7279\u6b8a\u7684\u5de5\u5177\uff0c\u6eda\u52a8\u5fae\u9488\uff08RMNs\uff09\u3002\u9996\u5148\u5728\u62c9\u4f38\u7684PDMS\u6a21\u5177\u4e0a\u5782\u76f4\u6eda\u52a8\u51fa\u8d1f\u6a21\uff0c\u518d\u586b\u5145\u6240\u9700\u7684\u6750\u6599\uff0c\u771f\u7a7a\u5e72\u71e5\uff0c\u6700\u7ec8\u5f97\u5230MNs\uff08\u56fe2\uff09\u3002\u5982RMNs\u5728\u672c\u6587\u7814\u7a76\u4e2d\u53d1\u6325\u4e86\u4e24\u79cd\u4f5c\u7528\uff0c\u9664\u4e86\u4e0a\u6587\u63d0\u53ca\u7684\u4f5c\u4e3a\u5236\u5907\u5fae\u9488\u7684\u6a21\u5177\uff0c\u53e6\u4e00\u4f5c\u7528\u662f\u5728\u819c\u4e0a\u521b\u5efa\u5b54\u6d1e\uff0c\u8fd9\u4e9b\u5b54\u6d1e\u88ab\u8bbe\u8ba1\u5728\u7279\u5b9a\u7684\u4f4d\u7f6e\uff0c\u5b8c\u62103D\u5fae\u6d41\u63a7\u901a\u9053\u7684\u6784\u5efa\uff0c\u5b9e\u73b0\u53cc\u9762\u6e17\u900f\u548c\u56fe\u6848\u5316\u8bbe\u8ba1, \u4ee5\u65b9\u4fbf\u836f\u7269\u548c\u5316\u9a8c\u7684\u8f93\u9001\u3002\u5f53\u5f85\u6d4b\u6db2\u987a\u7740\u5fae\u6d41\u63a7\u901a\u9053\u81ea\u9a71\u6d41\u52a8\uff0c\u5230\u5b54\u6d1e\u4f4d\u7f6e\u65f6\uff0c\u5f85\u6d4b\u6db2\u5c06\u4f1a\u6d41\u5165\u7b2c\u4e8c\u5c42\uff0c\u518d\u987a\u7740\u901a\u9053\u53ca\u5b54\u6d1e\u5230\u8fbe\u7b2c\u4e09\u5c42\uff0c\u76f4\u81f3\u5230\u8fbe\u68c0\u6d4b\u533a\u3002RMNs\u8fd9\u79cd\u7b80\u4fbf\u7684\u5de5\u5177\uff0c\u4e3a\u521b\u5efa\u591a\u5c42\u9762\u5fae\u6d41\u4f53\u901a\u9053\u63d0\u4f9b\u4e86\u65b0\u601d\u8def\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-257876\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2024\/02\/2-16.png\" alt=\"\" width=\"600\" height=\"428\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2024\/02\/2-16.png 600w, \/\/m.iemloyee.com\/wp-content\/uploads\/2024\/02\/2-16-300x214.png 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/p>\n<p>\u56fe2. MMMs \u8d34\u7247\u7684\u5236\u4f5c\u8fc7\u7a0b\u548c\u8868\u5f81\u3002(A) \u5728 PDMS \u6a21\u5177\u4e0a\u6eda\u52a8 RMNs \u540e\u5269\u4f59\u5b54\u7684\u793a\u610f\u56fe\u3002\u62c9\u4f38\u6a21\u5177\u540e\uff0c\u5206\u522b\u586b\u5145\u4e1d\u7ea4\u7ef4\u86cb\u767d\u6eb6\u6db2\u548cEPC\u5355\u5206\u6563\u7eb3\u7c73\u7c92\u5b50\u3002\u5e72\u71e5\u540e\uff0c\u7528 RMNs\u7a7f\u5b54\uff0c\u6700\u540e\u5f97\u5230\u4e0d\u540c\u6750\u6599\u7684\u5e26\u5b54 \u7684MNs\u8d34\u7247\u3002(B) (i) RMNs \u7684\u5934\u90e8\u548c\u9488\u7ec6\u8282\u7684\u6b63\u9762\u548c\u4fa7\u9762\u793a\u610f\u56fe\uff08\u6bd4\u4f8b\u5c3a\uff1a25 mm\uff09\u3002(ii) \u793a\u610f\u56fe\u4ec5\u663e\u793a MNs \u548c\u7279\u5b9a\u5c40\u90e8\u7ec6\u8282\u3002(iii) \u793a\u610f\u56fe\u4ec5\u663e\u793a\u5355\u4fa7\u5b54\u53ca\u5176\u5c40\u90e8\u7ec6\u8282\u3002(iv\uff09\u540c\u65f6\u663e\u793a MN \u5f62\u6001\u548c\u5b54\u53ca\u5176\u5c40\u90e8\u7ec6\u8282\u7684\u793a\u610f\u56fe\uff08\u4ece ii \u5230 iv\uff1b\u6bd4\u4f8b\u5c3a\uff1a500 \u03bcm\uff09\u3002(C) \u4f7f\u7528 RMN \u8fdb\u884c\u8f67\u5236\u7684\u56fe\u6848\u793a\u610f\u56fe\u5206\u522b\u4e3a &#8220;A&#8221;\u3001&#8221;F&#8221;\u3001&#8221;M&#8221;\u3001&#8221;\u5341&#8221;\u3001&#8221;N&#8221;\u3001&#8221;K&#8221;\u3001&#8221;\uff03&#8221;\u548c &#8220;\u4e00&#8221;\uff08\u6bd4\u4f8b\u5c3a\uff1a15 \u6beb\u7c73\uff09\u3002<\/p>\n<p>2.MMMs\u4e0a\u7684\u751f\u7269\u4f20\u611f\u5668<\/p>\n<p>\u53d7\u5230\u5927\u81ea\u7136\u4e2d\u751f\u7269\u4f53\uff08\u95ea\u8776\u7fc5\u8180\uff0c\u5b54\u96c0\u7fbd\u6bdb\uff09\u53ca\u5229\u7528\u5468\u671f\u6027\u5fae\u89c2\u7ed3\u6784\uff0c\u521b\u9020\u51fa\u8bb8\u591a\u5f15\u4eba\u6ce8\u76ee\u7684\u7ed3\u6784\u8272\u7684\u542f\u53d1\u3002\u5229\u7528\u6392\u5217\u6709\u5e8f\u7684\u5355\u5206\u6563EPC\u7eb3\u7c73\u7c92\u5b50\uff0c\u81ea\u7ec4\u88c5\u5e72\u71e5\u5236\u5907\u4e86\u4eba\u5de5\u5408\u6210\u7684PC\u3002\u540c\u6837\u5177\u5907\u5468\u671f\u6027\u7ed3\u6784\uff0c\u6709\u9009\u62e9\u6027\u5730\u900f\u8fc7\u6216\u53cd\u5c04\u7279\u5b9a\u6ce2\u957f\u7684\u5149\u3002\u4f5c\u8005\u5c06RMNs\u4e0ePC\u819c\u7ed3\u5408\uff0c\u8bbe\u8ba1\u76843D\u591a\u5c42\u5fae\u6d41\u4f53\u901a\u9053\u89e3\u51b3\u4e86\u6d41\u4f53\u81ea\u53d1\u6d41\u52a8\u7684\u95ee\u9898\u3002\u7531\u4e8e\u6bdb\u7ec6\u4f5c\u7528\u529b\u7684\uff0c\u6d41\u4f53\u65e0\u9700\u5916\u90e8\u9a71\u52a8\u529b\u5373\u53ef\u81ea\u53d1\u6d41\u52a8\u3002\u968f\u540e\u6d41\u8fc7 PC \u819c\u65f6\u4f1a\u4ea7\u751f\u660e\u663e\u7684\u989c\u8272\u53cd\u5e94\uff0c\u8fd8\u5177\u6709\u8367\u5149\u589e\u5f3a\u7684\u529f\u80fd\uff08\u56fe3\uff09\uff0c\u53ef\u5e94\u7528\u4e8e\u76d1\u6d4b\u5c0f\u9f20\u4f24\u53e3\u7684\u708e\u75c7\u56e0\u5b50\uff08IL-6\u3001CRP\uff09\u3002\u57fa\u4e8e\u8fd9\u4e9b\u7279\u70b9\uff0c\u8fd9\u79cdMMMs\u5728\u4fc3\u8fdb\u7ec4\u7ec7\u518d\u751f\uff0c\u521b\u9762\u6108\u5408\u548c\u4f24\u53e3\u7ba1\u7406\u65b9\u9762\u7684\u5b9e\u7528\u6027\u80fd\u5df2\u901a\u8fc7\u5c0f\u9f20\u4f24\u53e3\u6a21\u578b\u7684\u5168\u5c42\u76ae\u80a4\u521b\u9762\u5f97\u5230\u8bc1\u5b9e\uff08\u56fe4\uff09\u3002\u8fd9\u4e9b\u7ed3\u679c\u8868\u660e\uff0cMMM\u5728\u4f24\u53e3\u6108\u5408\u3001\u7ec4\u7ec7\u5de5\u7a0b\u7b49\u751f\u7269\u533b\u5b66\u9886\u57df\u5177\u6709\u5e7f\u9614\u7684\u5e94\u7528\u524d\u666f\u3002\u603b\u4f53\u800c\u8a00\uff0c\u901a\u8fc7RMNs\u7684\u5236\u5907\u65b9\u6cd5\uff0c\u4e3a\u5fae\u6d41\u4f53\u82af\u7247\u7684\u8bbe\u8ba1\u548c\u6d41\u4f53\u63a7\u5236\u5f00\u8f9f\u4e86\u4e00\u6761\u521b\u65b0\u4e4b\u8def\u3002\u8fd9\u79cd\u751f\u7269\u542f\u53d1\u8d34\u7247\u4e0d\u4ec5\u5728\u4f24\u53e3\u7ba1\u7406\uff0c\u800c\u4e14\u5728\u4e34\u5e8a\u7ed9\u836f\u3001POCT\u7b49\u9886\u57df\u90fd\u5177\u6709\u5de8\u5927\u7684\u53d1\u5c55\u6f5c\u529b\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-257877\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2024\/02\/3-13.png\" alt=\"\" width=\"600\" height=\"358\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2024\/02\/3-13.png 600w, \/\/m.iemloyee.com\/wp-content\/uploads\/2024\/02\/3-13-300x179.png 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/p>\n<p>\u56fe3. MMMs \u8d34\u7247\u5bf9\u8367\u5149\u7684\u9009\u62e9\u6027\u589e\u5f3a\u793a\u610f\u56fe\u3002(A) (i) \u4e2d\u56fe\u50cf\u7684\u6570\u7801\u7167\u7247\u3002(ii)\u4e2dPC\u7231\u5fc3\u7684\u56fe\u6848\u5bf9\u4e0d\u540c pH \u503c\u6eb6\u6db2\u7684\u76f8\u5e94\u53cd\u5c04\u5149\u8c31\u3002(iii) PC\u7231\u5fc3\u7684\u56fe\u6848\u5728 550 nm\u6ce2\u957f\u5904\u7684\u53cd\u5c04\u7387\u968f\u6eb6\u6db2\u7684 pH \u503c\u53d8\u5316\u3002(iv) \u4e2d\u4e0d\u540c\u989c\u8272 PC \u8584\u819c\u7684\u53cd\u5c04\u7387\u3002(B) \u84dd\u8272 PC \u8584\u819c\u5931\u6c34\u540e\u53d8\u4e3a\u900f\u660e\u7684\u8fc7\u7a0b\u793a\u610f\u56fe\u3002(C) \u7ea2\u8272\u548c\u7eff\u8272 PC \u8584\u819c\u5728 0\u30010.25\u30010.5\u30010.75 \u548c 1.0 \u03bcg\/L \u7f57\u4e39\u660e\u7ea2\u8367\u5149\u67d3\u6599\u4e0b\u7684\u8367\u5149\u5f3a\u5ea6\u793a\u610f\u56fe\u3002(D) \u7ea2\u8272\u548c\u7eff\u8272 PC \u8584\u819c\u5728 0\u30010.25\u30010.5\u30010.75 \u548c 1.0 \u03bcg\/L \u7eff\u8272\u8367\u5149\u67d3\u6599\u4f5c\u7528\u4e0b\u7684\u8367\u5149\u5f3a\u5ea6\u793a\u610f\u56fe\u3002(E) 1 \u03bcg\/L \u7ea2\u8272\u6216\u7eff\u8272\u8367\u5149\u67d3\u6599\u5206\u522b\u5728\u900f\u660e\u73bb\u7483\u3001\u7ea2\u8272\u6216\u7eff\u8272 PC \u8584\u819c\u4e0a\u7684\u8367\u5149\u5f3a\u5ea6\u793a\u610f\u56fe\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-257878\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2024\/02\/4-12.png\" alt=\"\" width=\"600\" height=\"309\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2024\/02\/4-12.png 600w, \/\/m.iemloyee.com\/wp-content\/uploads\/2024\/02\/4-12-300x155.png 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/p>\n<p>\u56fe4 MMNs \u6577\u6599\u5bf9\u8868\u76ae\u4f24\u53e3\u7684\u6d3b\u4f53\u6cbb\u7597\u8bc4\u4f30 (A) \u4e0d\u540c\u7ec4\u522b\u5728 0\u30013\u30015 \u548c 12 \u5929\u7684\u4ee3\u8868\u6027\u7167\u7247\u548c\u4f24\u53e3\u8f6e\u5ed3\u3002(\u6bd4\u4f8b\u5c3a\uff1a6 \u6beb\u7c73\uff09\uff08\u5e73\u5747\u503c \u00b1 SD\uff1bn = 6\uff09\u3002(B) \u4e0d\u540c\u7ec4\u4f24\u53e3\u7684 HE \u67d3\u8272\u548c Masson \u67d3\u8272\uff1b\u7ea2\u8272\u7bad\u5934\u8868\u793a\u4f24\u53e3\u8fb9\u7f18\uff08\u6bd4\u4f8b\u5c3a\uff1a6 \u6beb\u7c73\uff09\u3002(C) PC \u7684\u8367\u5149\u5bf9 IL-6 \u548c CRP \u4e0d\u540c\u5904\u7406\u65f6\u95f4\u7684\u53cd\u5e94\uff08i\uff09\u3002\u5b83\u4eec\u7684\u8367\u5149\u5f3a\u5ea6\u6bd4\u8f83\u89c1 (ii)\u3002(D) \u4f24\u53e3\u9762\u79ef\u7684\u91cf\u5316\uff08\u5e73\u5747\u503c \u00b1 SD\uff1bn = 6\uff09\u3002(E) CT26 \u7ec6\u80de\u7684\u6d3b\/\u6b7b\u67d3\u8272\u56fe\u50cf\u3002<\/p>\n<p><strong>Part.4\/<\/strong><strong>\u603b\u7ed3\u4e0e\u5c55\u671b\uff1a<\/strong><\/p>\n<p>\u7efc\u4e0a\u6240\u8ff0\uff0c\u8be5\u7814\u7a76\u53d7\u751f\u7269\u542f\u53d1\u4f7f\u7528\u4e86 RMNs \u8bbe\u8ba1\u57fa\u4e8ePC\u7684\u65b0\u578b \u8d85\u7ed3\u6784\u5fae\u6d41\u4f53\u5fae\u9488\uff08MMMs\uff09 \u8d34\u7247\u3002\u4ee5\u8f74\u5411\u9635\u5217\u6392\u5217\u7684 RMNs \u4f5c\u4e3a\u7b80\u4fbf\u7684\u5fae\u9488\u8bbe\u8ba1\u6a21\u677f\uff0c\u540c\u65f6\u5728 PC \u819c\u4e0a\u8fdb\u884c\u4e86\u56fe\u6848\u5316\u8bbe\u8ba1\u4fc3\u8fdb\u4e86\u53cc\u9762\u6e17\u900f\uff0c\u5f62\u6210\u4e863D\u8d85\u7ed3\u6784\u5fae\u6d41\u4f53\u901a\u9053\u3002\u4e0ePC \u819c\u7684\u7ed3\u5408\uff0c\u53ef\u4ee5\u4ea7\u751f\u72ec\u7279\u7684\u7ed3\u6784\u8272\u548c\u8367\u5149\u589e\u5f3a\u4f5c\u7528\u3002\u4f5c\u8005\u5bf9\u5c0f\u9f20\u4f24\u53e3\u4e2d\u7684\u708e\u75c7\u56e0\u5b50\uff08\u5982 IL-6 \u548c CRP\uff09\u8fdb\u884c\u7684\u5b9e\u65f6\u76d1\u6d4b\u8bc1\u660e\u4e86 MMMs \u8d34\u7247\u5728\u4f24\u53e3\u7ba1\u7406\u548c\u751f\u7269\u533b\u5b66\u5e94\u7528\u65b9\u9762\u7684\u6f5c\u529b\u3002\u672c\u7814\u7a76\u5728\u6d41\u4f53\u63a7\u5236\u65b9\u9762\u5b9e\u73b0\u4e86\u7a81\u7834\uff0c\u4e3a\u4e34\u5e8a\u7ed9\u836f\u548c\u62a4\u7406\u70b9\u68c0\u6d4b\u7684\u5e94\u7528\u63d0\u4f9b\u4e86\u65b0\u7684\u53ef\u80fd\u6027\u3002<\/p>\n<p>\u8be5\u7814\u7a76\u5de5\u4f5c\u5f97\u5230\u4e86\u56fd\u5bb6\u81ea\u7136\u57fa\u91d1\u3001\u6c5f\u82cf\u7701\u81ea\u7136\u79d1\u5b66\u57fa\u91d1\u3001\u5357\u4eac\u5de5\u4e1a\u5927\u5b66\u836f\u5b66\u9662\u5b66\u79d1\u57fa\u91d1\u7b49\u9879\u76ee\u7684\u652f\u6301\u3002<\/p>\n<p>\u8bba\u6587\u94fe\u63a5\uff1ahttps:\/\/doi.org\/10.1002\/adfm.202316565.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u8fd1\u65e5\uff0c\u5357\u4eac\u5de5\u4e1a\u5927\u5b66\u836f\u5b66\u9662\u9ad8\u5175\u5175\u526f\u6559\u6388\u56e2\u961f\u5728\u56fd\u9645\u77e5\u540d\u6750\u6599\u79d1\u5b66\u5b66\u672f\u671f\u520a\u300aAdvanced Functional Materials\u300b\uff08IF=19.00\uff09\u53d1\u8868\u201cRol&#8230;<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[215],"tags":[],"class_list":["post-257874","post","type-post","status-publish","format-standard","hentry","category-jiedu"],"_links":{"self":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts\/257874"}],"collection":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=257874"}],"version-history":[{"count":1,"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts\/257874\/revisions"}],"predecessor-version":[{"id":257879,"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts\/257874\/revisions\/257879"}],"wp:attachment":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=257874"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=257874"},{"taxonomy":"post_tag","embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=257874"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}