{"id":257209,"date":"2024-01-16T06:38:00","date_gmt":"2024-01-15T22:38:00","guid":{"rendered":"\/\/m.iemloyee.com\/?p=257209"},"modified":"2024-01-15T16:42:16","modified_gmt":"2024-01-15T08:42:16","slug":"%e5%a4%9a%e6%a8%a1%e5%9d%97%e9%9b%86%e6%88%90%e7%9a%84%e8%b6%85%e5%88%86%e5%ad%90%e5%85%89%e6%95%8f%e5%89%82%e5%8d%8f%e5%90%8c%e5%a2%9e%e5%bc%ba%e5%85%89%e5%8a%a8%e5%8a%9b%e6%b2%bb%e7%96%97","status":"publish","type":"post","link":"\/\/m.iemloyee.com\/?p=257209","title":{"rendered":"\u591a\u6a21\u5757\u96c6\u6210\u7684\u8d85\u5206\u5b50\u5149\u654f\u5242\u534f\u540c\u589e\u5f3a\u5149\u52a8\u529b\u6cbb\u7597"},"content":{"rendered":"<p>\u5149\u52a8\u529b\u6cbb\u7597\uff08PDT\uff09\u662f\u5229\u7528\u5149\u654f\u5242\u5206\u5b50\u4ece\u5149\u4e2d\u83b7\u53d6\u80fd\u91cf\u751f\u6210\u6d3b\u6027\u6c27\uff0c\u4ece\u800c\u6740\u6b7b\u764c\u7ec6\u80de\u7684\u80bf\u7624\u6cbb\u7597\u65b9\u6cd5\uff0c\u56e0\u5176\u5177\u6709\u65f6\u7a7a\u9009\u62e9\u6027\u548c\u975e\u4fb5\u5165\u6027\u7b49\u4f18\u52bf\uff0c\u8fd1\u5e74\u6765\u53d7\u5230\u5e7f\u6cdb\u5173\u6ce8\u3002\u5149\u52a8\u529b\u6cbb\u7597\u4e2d\u5149\u654f\u5242\u6750\u6599\u7684\u6d3b\u6027\u6c27\u4ea7\u751f\u6548\u7387\u81f3\u5173\u91cd\u8981\u3002\u56e0\u6b64\uff0c\u76ee\u524d\u7684\u7814\u7a76\u5de5\u4f5c\u4e3b\u8981\u96c6\u4e2d\u4e8e\u5f00\u53d1\u65b0\u7684\u5149\u654f\u5242\u5206\u5b50\uff0c\u901a\u8fc7\u5f15\u5165\u5927\u5e73\u9762\u5171\u8f6d\u7ed3\u6784\u548c\u91cd\u539f\u5b50\u7b49\u5143\u7d20\u4fc3\u8fdb\u5206\u5b50\u5185\u7535\u8377\u5206\u79bb\u53ca\u63d0\u5347\u7cfb\u95f4\u8e7f\u8d8a\u6548\u7387\uff0c\u4ece\u800c\u5b9e\u73b0\u5149\u654f\u5242\u529f\u6548\u7684\u63d0\u5347\u3002\u9664\u4e86\u4ece\u5934\u8bbe\u8ba1\u5149\u654f\u5242\u5206\u5b50\u5916\uff0c\u5982\u80fd\u901a\u8fc7\u96c6\u6210\u5df2\u6709\u7684\u5149\u654f\u5242\u5206\u5b50\u7684\u65b9\u5f0f\u5b9e\u73b0\u6d3b\u6027\u6c27\u4ea7\u751f\u6548\u7387\u7684\u534f\u540c\u63d0\u9ad8\uff0c\u5c06\u4e3a\u5149\u654f\u5242\u6750\u6599\u7684\u53d1\u5c55\u63d0\u4f9b\u65b0\u601d\u8def\u3002<\/p>\n<p>\u8fd1\u65e5\uff0c\u6df1\u5733\u5927\u5b66\u738b\u6052\u526f\u6559\u6388\/\u7279\u8058\u7814\u7a76\u5458\u5728\u56fd\u9645\u77e5\u540d\u5b66\u672f\u671f\u520a\u300a<em><i>Angew. Chem. Int. Ed<\/i><\/em><em><i>.<\/i><\/em>\u300b\u4e0a\u53d1\u8868\u9898\u4e3a\u201cCombining Multiple Photosensitizer Modules into One Supramolecular System for Synergetic Enhancement of Photodynamic Therapy\u201d\uff08DOI: org\/10.1002\/anie.202400049\uff09\u7684\u7814\u7a76\u8bba\u6587\u3002\u8be5\u8bba\u6587\u5229\u7528\u5421\u5583-\u5421\u5576\u76d0\u5316\u5b66\u548c\u914d\u4f4d\u9a71\u52a8\u81ea\u7ec4\u88c5\u76f8\u7ed3\u5408\u7684\u7b56\u7565\uff08<em><i>J. Am. Chem. Soc. <\/i><\/em><strong><b>2023<\/b><\/strong>, <em><i>145<\/i><\/em>, 5191; <em><i>J. Am. Chem. Soc.<\/i><\/em>\u00a0<strong><b>2019<\/b><\/strong>, <em><i>141<\/i><\/em>, 16108; <em><i>J. Am. Chem. Soc.<\/i><\/em>\u00a0<strong><b>2019<\/b><\/strong>, <em><i>141<\/i><\/em>, 13187; <em><i>Nature Commun.<\/i><\/em><strong><b>\u00a02018<\/b><\/strong>, <em><i>9<\/i><\/em>, 1815\uff09\u5c06PDT\u5e38\u7528\u5149\u654f\u5242\u5206\u5b50\uff08\u56db\u82ef\u4e59\u70ef\u3001\u535f\u5549\u6216\u950c\u535f\u5549\uff09\u548c\u5421\u5576\u76d0\u5149\u654f\u5242\u5206\u5b50\u9ad8\u6548\u96c6\u6210\uff0c\u6784\u7b51\u4e86\u4e00\u7c7b\u65b0\u578b\u7684\u8d85\u5206\u5b50\u5149\u654f\u5242\uff0c\u5b9e\u73b0\u4e86\u5149\u52a8\u529b\u6cbb\u7597\u7684\u534f\u540c\u589e\u5f3a\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-257211\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2024\/01\/\u56fe\u7247-1-10.png\" alt=\"\" width=\"800\" height=\"389\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2024\/01\/\u56fe\u7247-1-10.png 800w, \/\/m.iemloyee.com\/wp-content\/uploads\/2024\/01\/\u56fe\u7247-1-10-300x146.png 300w, \/\/m.iemloyee.com\/wp-content\/uploads\/2024\/01\/\u56fe\u7247-1-10-768x373.png 768w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/><\/p>\n<p><strong><b>\u56fe1<\/b><\/strong>.\u00a0\u8d85\u5206\u5b50\u5149\u654f\u5242\u7684\u7ed3\u6784\u53ca\u5408\u6210\u8def\u7ebf\u3002<\/p>\n<p>\u57fa\u4e8e\u7ed3\u6784\u8bbe\u8ba1\u4ee5\u53ca\u591a\u7ef4\u6838\u78c1\u548c\u8d28\u8c31\u8bc1\u660e\uff0c\u6b64\u7c7b\u7b3c\u72b6\u914d\u4f4d\u8d85\u5206\u5b50\u5149\u654f\u5242\uff08S1\u2212S3\uff09\u5305\u542b\u4e24\u4e2a\u56db\u82ef\u4e59\u70ef\u3001\u535f\u5549\u6216\u950c\u535f\u5549\u5149\u654f\u5242\u6a21\u5757\u548c\u516b\u4e2a\u5421\u5576\u76d0\u5149\u654f\u5242\u6a21\u5757\uff08\u56fe1\uff09\u3002\u5149\u7269\u7406\u6027\u8d28\u7814\u7a76\u8868\u660e\u6a21\u5757\u96c6\u6210\u4e00\u65b9\u9762\u62d3\u5bbd\u4e86\u5438\u6536\u5149\u7684\u6ce2\u957f\u8303\u56f4\uff0c\u53e6\u4e00\u65b9\u9762\u4fc3\u8fdb\u4e86\u6a21\u5757\u95f4\u7684\u80fd\u91cf\u8f6c\u79fb\uff08\u56fe2\uff09\u3002\u5176\u4e2d\uff0c\u57fa\u4e8e\u535f\u5549\u7684\u8d85\u5206\u5b50\u5149\u654f\u5242S2\u5177\u6709\u4f18\u5f02\u7684\u7d2b\u5916-\u53ef\u89c1\u5149\u5438\u6536\u3001\u6700\u5927\u7684Stokes\u4f4d\u79fb\u4ee5\u53ca\u8f83\u5f3a\u7684\u8367\u5149\u91cf\u5b50\u4ea7\u7387\uff0c\u8868\u73b0\u51fa\u4e86\u5728PDT\u65b9\u9762\u7684\u5e94\u7528\u6f5c\u529b\u3002\u968f\u540e\uff0c\u5176\u5e94\u7528\u6f5c\u529b\u901a\u8fc7DFT\u7406\u8bba\u8ba1\u7b97\uff08\u56fe2\uff09\u548c\u6d3b\u6027\u6c27\u7269\u8d28\uff08ROS\uff09\u751f\u6210\u80fd\u529b\u7814\u7a76\uff08\u56fe3\uff09\u5f97\u5230\u4e86\u8bc1\u5b9e\u3002\u5f15\u4eba\u6ce8\u76ee\u7684\u662f\uff0cS2\u7684ROS\u751f\u6210\u80fd\u529b\u53ef\u4ee5\u8fbe\u5230\u5546\u4e1a\u5316\u5b5f\u52a0\u62c9\u73ab\u7470\u7ea2\uff08RB\uff09\u5149\u654f\u5242\u5206\u5b50\u768420\u500d\u3002\u5728\u4e0a\u8ff0\u7814\u7a76\u57fa\u7840\u4e0a\uff0c\u8fdb\u4e00\u6b65\u901a\u8fc7\u4e00\u7cfb\u5217\u7ec6\u80de\u548c\u52a8\u7269\u5b9e\u9a8c\u5bf9\u8d85\u5206\u5b50\u5149\u654f\u5242S2\u8fdb\u884c\u4e86\u8be6\u7ec6\u8bc4\u4f30\uff0c\u7ed3\u679c\u8868\u660eS2\u5177\u6709\u4f18\u5f02\u7684PDT\u7597\u6548\u3001\u751f\u7269\u76f8\u5bb9\u6027\u548c\u751f\u7269\u5b89\u5168\u6027\uff08\u56fe4\u548c5\uff09\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-257212\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2024\/01\/\u56fe\u7247-2-9.png\" alt=\"\" width=\"800\" height=\"565\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2024\/01\/\u56fe\u7247-2-9.png 800w, \/\/m.iemloyee.com\/wp-content\/uploads\/2024\/01\/\u56fe\u7247-2-9-300x212.png 300w, \/\/m.iemloyee.com\/wp-content\/uploads\/2024\/01\/\u56fe\u7247-2-9-768x542.png 768w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/><\/p>\n<p><strong><b>\u56fe<\/b><\/strong><strong><b>2<\/b><\/strong>.\u00a0\u8d85\u5206\u5b50\u5149\u654f\u5242\u53ca\u5176\u914d\u4f53\u7684\u5149\u7269\u7406\u6027\u8d28\u7814\u7a76\u548cDFT\u7406\u8bba\u8ba1\u7b97\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-257213\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2024\/01\/\u56fe\u7247-3-7.png\" alt=\"\" width=\"800\" height=\"649\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2024\/01\/\u56fe\u7247-3-7.png 800w, \/\/m.iemloyee.com\/wp-content\/uploads\/2024\/01\/\u56fe\u7247-3-7-300x243.png 300w, \/\/m.iemloyee.com\/wp-content\/uploads\/2024\/01\/\u56fe\u7247-3-7-768x623.png 768w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/><\/p>\n<p><strong><b>\u56fe<\/b><\/strong><strong><b>3<\/b><\/strong>.\u00a0\u8d85\u5206\u5b50\u5149\u654f\u5242\u53ca\u5bf9\u7167\u7ec4\u7684\u6d3b\u6027\u6c27\u7269\u8d28\u751f\u6210\u80fd\u529b\u8bc4\u4f30\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-257214\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2024\/01\/\u56fe\u7247-4-6.png\" alt=\"\" width=\"800\" height=\"443\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2024\/01\/\u56fe\u7247-4-6.png 800w, \/\/m.iemloyee.com\/wp-content\/uploads\/2024\/01\/\u56fe\u7247-4-6-300x166.png 300w, \/\/m.iemloyee.com\/wp-content\/uploads\/2024\/01\/\u56fe\u7247-4-6-768x425.png 768w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/><\/p>\n<p><strong><b>\u56fe<\/b><\/strong><strong><b>4<\/b><\/strong>.\u00a0\u4f53\u5916\u5149\u52a8\u529b\u6cbb\u7597\u8bc4\u4f30\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-257215\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2024\/01\/\u56fe\u7247-5-3.png\" alt=\"\" width=\"800\" height=\"938\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2024\/01\/\u56fe\u7247-5-3.png 800w, \/\/m.iemloyee.com\/wp-content\/uploads\/2024\/01\/\u56fe\u7247-5-3-256x300.png 256w, \/\/m.iemloyee.com\/wp-content\/uploads\/2024\/01\/\u56fe\u7247-5-3-768x900.png 768w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/><\/p>\n<p><strong><b>\u56fe<\/b><\/strong><strong><b>5<\/b><\/strong>.\u00a0\u4f53\u5185\u5149\u52a8\u529b\u6cbb\u7597\u8bc4\u4f30\u3002<\/p>\n<p>\u7efc\u4e0a\u6240\u8ff0\uff0c\u672c\u8bba\u6587\u901a\u8fc7\u7b80\u5355\u7684\u6a21\u5757\u96c6\u6210\u7b56\u7565\u6210\u529f\u5730\u5236\u5907\u4e86\u4e00\u7c7b\u9ad8\u6548\u7684\u8d85\u5206\u5b50\u5149\u654f\u5242\uff0c\u5b9e\u73b0\u4e86\u5149\u52a8\u529b\u6cbb\u7597\u7684\u534f\u540c\u589e\u5f3a\u3002\u57fa\u4e8e\u6b64\uff0c\u5c06\u6765\u6709\u671b\u901a\u8fc7\u6539\u53d8\u6a21\u5757\u7684\u5f62\u72b6\u3001\u5c3a\u5bf8\u3001\u5438\u6536\u6ce2\u957f\u8303\u56f4\u3001\u764c\u7ec6\u80de\u7684\u9776\u5411\u6027\u548c\u6c34\u6eb6\u6027\u7b49\u7279\u6027\uff0c\u5b9e\u73b0\u8d85\u5206\u5b50\u5149\u654f\u5242\u7684\u6027\u8d28\u548c\u529f\u80fd\u7684\u6309\u9700\u8c03\u63a7\uff0c\u4e3a\u5f00\u53d1\u80fd\u591f\u5728\u4e34\u5e8a\u5e94\u7528\u7684\u9ad8\u6548\u5149\u654f\u5242\u5f00\u8f9f\u4e86\u4e00\u6761\u65b0\u7684\u9053\u8def\u3002<\/p>\n<p>\u6587\u7ae0\u7684\u7b2c\u4e00\u4f5c\u8005\u662f\u6df1\u5733\u5927\u5b66\u7684\u674e\u5fd7\u51ef\u535a\u58eb\u548c\u5f20\u5fd7\u519b\u52a9\u7406\u6559\u6388\/\u7279\u8058\u7814\u7a76\u5458\uff0c\u7406\u8bba\u8ba1\u7b97\u7531\u90d1\u5dde\u5927\u5b66\u7684\u5f20\u6587\u9759\u526f\u6559\u6388\u5b8c\u6210\u3002<\/p>\n<p>\u8bba\u6587\u94fe\u63a5\uff1a<a href=\"https:\/\/doi.org\/10.1002\/anie.202400049\">https:\/\/doi.org\/10.1002\/anie.202400049<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u5149\u52a8\u529b\u6cbb\u7597\uff08PDT\uff09\u662f\u5229\u7528\u5149\u654f\u5242\u5206\u5b50\u4ece\u5149\u4e2d\u83b7\u53d6\u80fd\u91cf\u751f\u6210\u6d3b\u6027\u6c27\uff0c\u4ece\u800c\u6740\u6b7b\u764c\u7ec6\u80de\u7684\u80bf\u7624\u6cbb\u7597\u65b9\u6cd5\uff0c\u56e0\u5176\u5177\u6709\u65f6\u7a7a\u9009\u62e9\u6027\u548c\u975e\u4fb5\u5165\u6027\u7b49\u4f18\u52bf\uff0c\u8fd1\u5e74\u6765\u53d7\u5230\u5e7f\u6cdb\u5173\u6ce8\u3002\u5149\u52a8\u529b\u6cbb\u7597\u4e2d&#8230;<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[215],"tags":[],"class_list":["post-257209","post","type-post","status-publish","format-standard","hentry","category-jiedu"],"_links":{"self":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts\/257209"}],"collection":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=257209"}],"version-history":[{"count":2,"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts\/257209\/revisions"}],"predecessor-version":[{"id":257216,"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts\/257209\/revisions\/257216"}],"wp:attachment":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=257209"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=257209"},{"taxonomy":"post_tag","embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=257209"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}