{"id":232722,"date":"2022-02-04T08:34:37","date_gmt":"2022-02-04T00:34:37","guid":{"rendered":"\/\/m.iemloyee.com\/?p=232722"},"modified":"2022-02-04T08:34:37","modified_gmt":"2022-02-04T00:34:37","slug":"%e4%bb%8a%e6%97%a5sciencec-h%e9%94%ae%e8%bd%ac%e6%8d%a2%e5%ae%9e%e7%8e%b0%e9%87%8d%e5%a4%a7%e7%aa%81%e7%a0%b4","status":"publish","type":"post","link":"\/\/m.iemloyee.com\/?p=232722","title":{"rendered":"\u4eca\u65e5Science:C-H\u952e\u8f6c\u6362\u5b9e\u73b0\u91cd\u5927\u7a81\u7834"},"content":{"rendered":"<p><strong><b>\u3010\u5f15\u8a00\u3011<\/b><\/strong><\/p>\n<p>\u9009\u62e9\u6027\u5730\u5c06\u4e0d\u540c\u5b98\u80fd\u56e2\u5f15\u5165C-H\u5316\u5408\u7269\u7684\u80fd\u529b\u5728\u5c0f\u5206\u5b50\u548c\u805a\u5408\u7269\u7684\u5408\u6210\u4e2d\u5177\u6709\u91cd\u8981\u4ef7\u503c\uff0c\u53ef\u4ee5\u4ece\u73b0\u6210\u7684\u5316\u5408\u7269\u4e2d\u83b7\u53d6\u5177\u6709\u589e\u5f3a\u7279\u6027\u7684\u590d\u6742\u5206\u5b50\u548c\u6750\u6599\u3002\u5c3d\u7ba1\u53d6\u5f97\u4e86\u5b9e\u8d28\u6027\u8fdb\u5c55\uff0c\u4f46\u4ecd\u7136\u8feb\u5207\u9700\u8981\u8102\u80aa\u65cfC-H\u591a\u6837\u5316\u3002\u636e\u4f30\u8ba1\uff0c\u5851\u6599\u5728\u4e00\u6b21\u4f7f\u7528\u540e\u4f1a\u635f\u593195%\u7684\u7ecf\u6d4e\u4ef7\u503c\u3002\u5177\u4f53\u6765\u8bf4\uff0c\u652f\u94fe\u805a\u70ef\u70c3\u5360\u5168\u7403\u751f\u4ea7\u805a\u5408\u7269\u7684 35%\u4ee5\u4e0a\uff0c\u4f46\u5728\u673a\u68b0\u518d\u52a0\u5de5\u6216\u805a\u5408\u7269\u529f\u80fd\u5316\u8fc7\u7a0b\u4e2d\u4f1a\u53d1\u751f\u6709\u5bb3\u7684\u65ad\u94fe\uff0c\u8fd9\u4f1a\u964d\u4f4e\u5176\u70ed\u673a\u68b0\u6027\u80fd\u5e76\u5bfc\u81f4\u5176\u56de\u6536\u7387\u4f4e\u3002\u5f00\u53d1\u5408\u6210\u65b9\u6cd5\u4ee5\u5728\u4f7f\u7528\u540e\u7684\u652f\u5316\u805a\u70ef\u70c3\u4e0a\u6dfb\u52a0\u6240\u9700\u7684\u5b98\u80fd\u56e2\u5c06\u4f7f\u5f97\u4ece\u6df7\u5408\u5851\u6599\u5e9f\u6599\u4e2d\u83b7\u53d6\u6027\u80fd\u4f18\u8d8a\u7684\u70ed\u5851\u6027\u5851\u6599\u3002\u76ee\u524d\uff0c\u5b58\u5728\u8bb8\u591a\u8102\u80aa\u65cfC-H\u952e\u7684\u8f6c\u53d8\uff0c\u5e76\u7528\u4e8e\u836f\u7269\u6837\u5206\u5b50\u548c\u5546\u54c1\u805a\u5408\u7269\u7684\u540e\u671f\u591a\u6837\u5316\uff0c\u4f46\u5176\u4e2d\u5927\u591a\u6570\u4f7f\u7528\u5bfc\u5411\u57fa\u56e2\u6765\u63a7\u5236\u53cd\u5e94\u4f4d\u70b9\u9009\u62e9\u6027\u6216\u6d89\u53ca\u6df7\u6742\u7684\u53cd\u5e94\u4e2d\u95f4\u4f53\uff0c\u8fd9\u9650\u5236\u4e86\u65b9\u6cd5\u9009\u62e9\u7684\u8303\u56f4\u3002\u65e0\u8bba\u91c7\u7528\u4f55\u79cd\u65b9\u6cd5\uff0c\u51e0\u79cd\u6709\u4ef7\u503c\u7684C-H\u8f6c\u5316\uff0c\u4f8b\u5982\u8102\u80aa\u65cfC-H\u7898\u5316\u548cC-H\u7532\u57fa\u5316\uff0c\u90fd\u4ecd\u7136\u53d7\u5230\u9650\u5236\u3002\u6700\u8fd1\u7684\u7814\u7a76\u8868\u660e\uff0c\u6742\u539f\u5b50\u4e2d\u5fc3\u81ea\u7531\u57fa\u53ef\u4fc3\u8fdb\u5404\u79cd\u5c0f\u5206\u5b50\u548c\u6750\u6599\u4e0a\u672a\u6d3b\u5316\u7684\u8102\u80aa\u65cfC-H\u952e\u7684\u4f4d\u70b9\u9009\u62e9\u6027\u3001\u5206\u5b50\u95f4\u529f\u80fd\u5316\uff0c\u6784\u6210\u91d1\u5c5e\u50ac\u5316\u65b9\u6cd5\u7684\u8865\u5145\u7b56\u7565\u3002\u8fd9\u4e9b\u53cd\u5e94\u4e3b\u8981\u5229\u7528\u8c03\u8c10\u7684\u3001\u4ee5\u6c2e\u4e3a\u4e2d\u5fc3\u7684\u81ea\u7531\u57fa\u7684\u80fd\u529b\uff0c\u4ee5\u5b9e\u73b0\u4ece\u5f3a\u7684\u3001\u672a\u6d3b\u5316\u7684\u8102\u80aa\u65cfC-H\u4f4d\u70b9\u8f7b\u677e\u8f6c\u79fb\u6c22\u539f\u5b50\uff08HAT\uff09\u3002\u8fd9\u4e9b\u5148\u524d\u7814\u7a76\u7684\u4e00\u4e2a\u5173\u952e\u7f3a\u70b9\u662f\u9700\u8981\u76f4\u63a5\u57fa\u56e2\u8f6c\u79fb\u9644\u52a0\u5728\u6c2e\u4e0a\u7684\u529f\u80fd\uff0c\u8fd9\u6781\u5927\u5730\u9650\u5236\u4e86\u53ef\u901a\u8fc7HAT\u5f97\u5230\u4ea7\u54c1\u591a\u6837\u6027\u7684\u53ef\u80fd\u6027\u3002<\/p>\n<p>\u4eca\u65e5\uff0c<strong><b>\u7f8e\u56fd<\/b><\/strong><strong><b>\u5317\u5361\u7f57\u6765\u7eb3\u5927\u5b66\u6559\u5802\u5c71\u5206\u6821Erik J. Alexanian<\/b><\/strong><strong><b>\u6559\u6388\u548cFrank A. Leibfarth\u6559\u6388<\/b><\/strong><strong><b>\uff08<\/b><\/strong><strong><b>\u5171\u540c<\/b><\/strong><strong><b>\u901a\u8baf\u4f5c\u8005\uff09<\/b><\/strong>\u62a5\u544a\u4e86\u4e00\u79cd\u4f7f\u7528\u81ea\u7531\u57fa\u94fe\u8f6c\u79fb\u6765\u5b9e\u73b0\u8102\u80aa\u65cf\u78b3\u6c22\u952e\u591a\u6837\u5316\u7684\u65b9\u6cd5\uff0c\u8be5\u65b9\u6cd5\u4f7f\u7528\u5177\u6709\u6613\u4e8e\u5236\u5907\u7684O-alkenylhydroxamate\u8bd5\u5242\uff0c\u5728\u6e29\u548c\u52a0\u70ed\u540e\u53ef\u4fc3\u8fdb\u5c0f\u5206\u5b50\u548c\u805a\u70ef\u70c3\u7684\u4e00\u7cfb\u5217\u5177\u6709\u6311\u6218\u6027\u6216\u4ee5\u524d\u672a\u5f00\u53d1\u7684\u8102\u80aa\u65cf\u78b3-\u6c22\u952e\u529f\u80fd\u5316\u3002\u5b9e\u9645\u4e0a\uff0c\u53ef\u4ee5\u5728\u4e0d\u7acb\u5373\u6355\u83b7\u78b3\u7684\u60c5\u51b5\u4e0b\u53bb\u9664\u6c22\uff0c\u8bd5\u5242\u7684\u52a0\u70ed\u6216\u5149\u89e3\u4ea7\u751f\u4e00\u5bf9\u81ea\u7531\u57fa\uff0c\u5176\u4e2d\u4e00\u4e2a\u8fc5\u901f\u88c2\u89e3C-H\u952e\uff0c\u800c\u53e6\u4e00\u4e2a\u4fdd\u6301\u76f8\u5bf9\u60f0\u6027\u3002\u7136\u540e\uff0c\u5404\u79cd\u5404\u6837\u7684\u5176\u4ed6\u81ea\u7531\u57fa\u6e90\u53ef\u4ee5\u4ecb\u5165\u5f62\u6210\u78b3-\u5364\u7d20\u3001\u78b3-\u78b3\u548c\u78b3-\u786b\u952e\u3002\u5c06\u54aa\u5511\u9393\u57fa\u56e2\u6dfb\u52a0\u5230\u805a\u4e59\u70ef\u6ce1\u6cab\u4e2d\u7684\u4e24\u6b65\u5347\u7ea7\u5faa\u73af\u5e8f\u5217\u4ea7\u751f\u4e86\u6f5c\u5728\u6709\u4ef7\u503c\u7684\u79bb\u805a\u7269\u3002\u8fd9\u79cd\u5e7f\u6cdb\u7684\u53cd\u5e94\u5e73\u53f0\u4f7f\u7528\u4e8e\u5904\u7406\u5851\u6599\u5e9f\u7269\u7684\u57fa\u7840\u8bbe\u65bd\u4e2d\u6d88\u8d39\u540e\u7684\u805a\u70ef\u70c3\u529f\u80fd\u5316\u3002\u6b64\u5916\uff0c\u4f7f\u7528\u78b3\u6c22\u952e\u529f\u80fd\u5316\u5c06\u79bb\u5b50\u5b98\u80fd\u56e2\u5316\u5b66\u9009\u62e9\u6027\u5730\u653e\u7f6e\u5230\u652f\u5316\u805a\u70ef\u70c3\u4e0a\uff0c\u5c06\u6750\u6599\u4ece\u70ed\u5851\u6027\u5851\u6599\u5347\u7ea7\u4e3a\u5177\u6709\u9ad8\u4ef7\u503c\u805a\u70ef\u70c3\u79bb\u805a\u7269\u62c9\u4f38\u6027\u80fd\u7684\u575a\u97e7\u5f39\u6027\u4f53\u3002\u76f8\u5173\u7814\u7a76\u6210\u679c\u4ee5\u201c<strong><em><b><i>Diversification of aliphatic C-H bonds in small molecules and polyolefins through radical chain transfer<\/i><\/b><\/em><\/strong>\u201d\u4e3a\u9898\u53d1\u8868\u5728<strong><em><b><i>Science<\/i><\/b><\/em><\/strong>\u4e0a\u3002<img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-232723\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2022\/02\/\u5c01\u9762.jpg\" alt=\"\" width=\"600\" height=\"233\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2022\/02\/\u5c01\u9762.jpg 600w, \/\/m.iemloyee.com\/wp-content\/uploads\/2022\/02\/\u5c01\u9762-300x117.jpg 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/p>\n<p><strong><b>\u3010\u56fe\u6587\u5bfc\u8bfb\u3011<\/b><\/strong><\/p>\n<p><strong><b>\u56fe\u4e00<\/b><\/strong><strong><b>\u3001\u4f7f\u7528<\/b><\/strong><strong><b>N<\/b><\/strong><strong><b>-\u529f\u80fd\u5316\u9170\u80fa\u7684\u8102\u80aa\u65cfC-H\u591a\u6837\u5316<\/b><\/strong><strong><b><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-232724\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2022\/02\/\u56fe1.jpg\" alt=\"\" width=\"600\" height=\"617\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2022\/02\/\u56fe1.jpg 600w, \/\/m.iemloyee.com\/wp-content\/uploads\/2022\/02\/\u56fe1-292x300.jpg 292w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/b><\/strong><\/p>\n<p><strong><b>\u56fe\u4e8c<\/b><\/strong><strong><b>\u3001\u4f7f\u7528\u8bd5\u52421\u5bf9\u5c0f\u5206\u5b50\u8fdb\u884cC-H\u591a\u6837\u5316<\/b><\/strong><strong><b><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-232725\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2022\/02\/\u56fe2.jpg\" alt=\"\" width=\"600\" height=\"701\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2022\/02\/\u56fe2.jpg 600w, \/\/m.iemloyee.com\/wp-content\/uploads\/2022\/02\/\u56fe2-257x300.jpg 257w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/b><\/strong><\/p>\n<p><strong><b>\u56fe\u4e09<\/b><\/strong><strong><b>\u3001\u4f7f\u7528\u8bd5\u52421\u5bf9\u805a\u70ef\u70c3\u8fdb\u884cC-H\u591a\u6837\u5316<\/b><\/strong><strong><b><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-232726\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2022\/02\/\u56fe3.jpg\" alt=\"\" width=\"600\" height=\"369\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2022\/02\/\u56fe3.jpg 600w, \/\/m.iemloyee.com\/wp-content\/uploads\/2022\/02\/\u56fe3-300x185.jpg 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/b><\/strong><\/p>\n<p><strong><b>\u56fe<\/b><\/strong><strong><b>\u56db<\/b><\/strong><strong><b>\u3001\u901a\u8fc7C-H\u5b98\u80fd\u5316\u83b7\u5f97\u805a\u70ef\u70c3\u79bb\u805a\u7269<\/b><\/strong><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-232727\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2022\/02\/\u56fe4.jpg\" alt=\"\" width=\"600\" height=\"245\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2022\/02\/\u56fe4.jpg 600w, \/\/m.iemloyee.com\/wp-content\/uploads\/2022\/02\/\u56fe4-300x123.jpg 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/p>\n<p><strong><b>\u6587\u732e\u94fe\u63a5<\/b><\/strong>\uff1a\u201c<a href=\"https:\/\/www.science.org\/doi\/10.1126\/science.abh4308\"><strong><u><b>Diversification of aliphatic C-H bonds in small molecules and polyolefins through radical chain transfer<\/b><\/u><\/strong><\/a>\u201d<strong><b>(<\/b><\/strong><strong><b>Science<\/b><\/strong><strong><b>\uff0c202<\/b><\/strong><strong><b>2<\/b><\/strong><strong><b>\uff0c<\/b><\/strong><a href=\"https:\/\/doi.org\/10.1126\/science.abh4308\"><strong><b>10.1126\/science.abh4308<\/b><\/strong><\/a><strong><b>)<\/b><\/strong><\/p>\n<p>\u672c\u6587\u7531\u6750\u6599\u4ebaCYM\u7f16\u8bd1\u4f9b\u7a3f\u3002\u6b22\u8fce\u5927\u5bb6\u5230\u6750\u6599\u4eba\u5ba3\u4f20\u79d1\u6280\u6210\u679c\u5e76\u5bf9\u6587\u732e\u8fdb\u884c\u6df1\u5165\u89e3\u8bfb\uff0c\u6295\u7a3f\u90ae\u7bb1tougao@cailiaoren.com\u3002<\/p>\n<p>\u6750\u6599\u4eba\u6295\u7a3f\u4ee5\u53ca\u5185\u5bb9\u5408\u4f5c\u53ef\u52a0\u7f16\u8f91\u5fae\u4fe1\uff1acailiaokefu\u3002<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u3010\u5f15\u8a00\u3011 \u9009\u62e9\u6027\u5730\u5c06\u4e0d\u540c\u5b98\u80fd\u56e2\u5f15\u5165C-H\u5316\u5408\u7269\u7684\u80fd\u529b\u5728\u5c0f\u5206\u5b50\u548c\u805a\u5408\u7269\u7684\u5408\u6210\u4e2d\u5177\u6709\u91cd\u8981\u4ef7\u503c\uff0c\u53ef\u4ee5\u4ece\u73b0\u6210\u7684\u5316\u5408\u7269\u4e2d\u83b7\u53d6\u5177\u6709\u589e\u5f3a\u7279\u6027\u7684\u590d\u6742\u5206\u5b50\u548c\u6750\u6599\u3002\u5c3d\u7ba1\u53d6\u5f97\u4e86\u5b9e\u8d28\u6027&#8230;<\/p>\n","protected":false},"author":9629,"featured_media":232723,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[215],"tags":[155],"class_list":["post-232722","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-jiedu","tag-science"],"_links":{"self":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts\/232722"}],"collection":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/users\/9629"}],"replies":[{"embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=232722"}],"version-history":[{"count":1,"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts\/232722\/revisions"}],"predecessor-version":[{"id":232728,"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts\/232722\/revisions\/232728"}],"wp:featuredmedia":[{"embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/media\/232723"}],"wp:attachment":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=232722"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=232722"},{"taxonomy":"post_tag","embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=232722"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}