{"id":221499,"date":"2021-05-13T06:39:20","date_gmt":"2021-05-12T22:39:20","guid":{"rendered":"\/\/m.iemloyee.com\/?p=221499"},"modified":"2021-05-12T21:39:40","modified_gmt":"2021-05-12T13:39:40","slug":"%e4%b8%8a%e6%b5%b7%e4%ba%a4%e9%80%9a%e5%a4%a7%e5%ad%a6%e5%8c%bb%e5%ad%a6%e9%99%a2%e6%9d%a8%e6%9c%9d%e5%8b%87%e7%8e%8b%e7%82%9cacc-chem-res-%e8%82%a0%e9%81%93%e4%b8%ad%e7%9a%84%e5%85%b1%e7%94%9f","status":"publish","type":"post","link":"\/\/m.iemloyee.com\/?p=221499","title":{"rendered":"\u4e0a\u6d77\u4ea4\u901a\u5927\u5b66\u533b\u5b66\u9662\u6768\u671d\u52c7&#038;\u738b\u709cAcc. Chem. Res.:\u80a0\u9053\u4e2d\u7684\u5171\u751f\u5fae\u751f\u7269\u548c\u81f4\u75c5\u7ec6\u83cc\u7684\u6210\u50cf"},"content":{"rendered":"<p>\u3010<strong><b>\u5f15\u8a00<\/b><\/strong>\u3011<\/p>\n<p>\u4f5c\u4e3a\u4e00\u4e2a\u65b0\u53d1\u73b0\u7684\u5668\u5b98\uff0c\u5728\u8fc7\u53bb\u7684\u4e8c\u5341\u5e74\u4e2d\uff0c\u80a0\u9053\u83cc\u7fa4\u5f97\u5230\u4e86\u5e7f\u6cdb\u7684\u7814\u7a76\uff0c\u5b83\u4eec\u5728\u5bbf\u4e3b\u4f17\u591a\u5668\u5b98\u548c\u7cfb\u7edf\u7684\u751f\u7406\u75c5\u7406\u8fc7\u7a0b\u4e2d\u7684\u9ad8\u5ea6\u591a\u6837\u5316\u548c\u57fa\u7840\u6027\u7684\u4f5c\u7528\u9010\u6e10\u88ab\u63ed\u793a\u3002\u4f46\u662f\uff0c\u5f53\u524d\u5927\u591a\u6570\u7814\u7a76\u4e25\u91cd\u4f9d\u8d56\u4e8eDNA\u6d4b\u5e8f\u7684\u65b9\u6cd5\u3002\u4e3a\u4e86\u771f\u6b63\u4e86\u89e3\u5171\u751f\u548c\u81f4\u75c5\u6027\u80a0\u9053\u7ec6\u83cc\u8868\u73b0\u51fa\u7684\u590d\u6742\u529f\u80fd\uff0c\u6211\u4eec\u9700\u8981\u66f4\u5f3a\u5927\u7684\u65b9\u6cd5\u548c\u5de5\u5177\uff0c\u5176\u4e2d\u6700\u9002\u5408\u7684\u6210\u50cf\u7b56\u7565\u662f\u80fd\u591f\u5728\u4e0d\u540c\u73af\u5883\u4e2d\u63a5\u8fd1\u8be5\u751f\u6001\u7cfb\u7edf\u539f\u4f4d\u72b6\u6001\u7684\u7b56\u7565\u3002\u5c3d\u7ba1 \u201c\u6697\u7269\u8d28\u201d\u8fd9\u4e00\u8bf4\u6cd5\u7ecf\u5e38\u88ab\u7528\u6765\u6307\u8bb8\u591a\u80a0\u9053\u7ec6\u83cc\u7684\u4e0d\u53ef\u57f9\u517b\u6027\uff0c\u4f46\u5b83\u4e5f\u53ef\u7528\u4e8e\u63cf\u8ff0\u5728\u80a0\u9053\u4e2d\u53ef\u89c6\u5316\u8fd9\u4e9b\u5fae\u751f\u7269\u65f6\u7684\u5de8\u5927\u56f0\u96be\u3002\u4e3a\u4e86\u5f00\u53d1\u5408\u9002\u7684\uff0c\u591a\u529f\u80fd\u7684\u5316\u5b66\u548c\u751f\u7269\u5b66\u5de5\u5177\u6765\u5bf9\u80a0\u9053\u7ec6\u83cc\u8fdb\u884c\u6210\u50cf\uff0c\u79d1\u7814\u5de5\u4f5c\u8005\u5728\u8fc7\u53bb\u7684\u51e0\u5e74\u4e2d\u4ed8\u51fa\u4e86\u5de8\u5927\u7684\u52aa\u529b\u3002<\/p>\n<p>\u3010<strong><b>\u6210\u679c\u7b80\u4ecb<\/b><\/strong>\u3011<\/p>\n<p>\u5728\u6b64\u7efc\u8ff0\u4e2d\uff0c<strong><b>\u4e0a\u6d77\u4ea4\u901a\u5927\u5b66<\/b><\/strong><strong><b>\u533b\u5b66\u9662\u6768\u671d\u52c7<\/b><\/strong><strong><b>&amp;<\/b><\/strong><strong><b>\u738b\u709c<\/b><\/strong>\u91cd\u70b9\u4ecb\u7ecd\u4e86\u5176\u56e2\u961f\u548c\u5176\u4ed6\u5b9e\u9a8c\u5ba4\u5728\u5f00\u53d1\u80a0\u9053\u4e2d\u5171\u751f\u5fae\u751f\u7269\u548c\u81f4\u75c5\u83cc\u53ef\u89c6\u5316\u7b56\u7565\u65b9\u9762\u7684\u6700\u65b0\u8fdb\u5c55\u3002\u9996\u5148\uff0c\u4f5c\u8005\u603b\u7ed3\u4e86\u5728\u5f00\u53d1\u6297\u751f\u7d20\u884d\u751f\u7684\u8367\u5149\u63a2\u9488\u65b9\u9762\u6240\u505a\u7684\u52aa\u529b\uff0c\u8be5\u63a2\u9488\u76f4\u63a5\u7ed3\u5408\u7279\u5b9a\u7684\u7ec6\u83cc\u8868\u9762\u7ed3\u6784\uff0c\u4ee5\u5b9e\u73b0\u9009\u62e9\u6027\u6807\u8bb0\u4e0d\u540c\u79cd\u7c7b\u7684\u80a0\u9053\u7ec6\u83cc\u3002\u63a5\u4e0b\u6765\uff0c\u8be6\u7ec6\u8ba8\u8bba\u4e86\uff0c\u57fa\u4e8e\u4ee3\u8c22\u6807\u8bb0\u7684\u975e\u5929\u7136\u7cd6\u548c\u7a33\u5b9a\u540c\u4f4d\u7d20\u7684\u6210\u50cf\u7b56\u7565\uff0c\u5728\u4e0d\u540c\u60c5\u666f\u4e2d\u548c\u591a\u79cd\u5c3a\u5ea6\u4e0a\u5bf9\u80a0\u9053\u7ec6\u83cc\u8fdb\u884c\u6210\u50cf\u3002\u7136\u540e\uff0c\u6587\u7ae0\u4ecb\u7ecd\u4e86\u57fa\u4e8e\u6838\u9178\u67d3\u8272\u7684\u7ec6\u83cc\u6210\u50cf\uff0c\u4f7f\u7528\u4e00\u822c\u7684\u6838\u9178\u7ed3\u5408\u8bd5\u5242\u6216\u9009\u62e9\u6027\u6807\u8bb0\u6280\u672f\uff08\u4f8b\u5982\u8367\u5149\u539f\u4f4d\u6742\u4ea4\uff08FISH\uff09\uff09\u6765\u6ee1\u8db3\u5404\u79cd\u5e94\u7528\u573a\u666f\u4e2d\u80a0\u9053\u83cc\u7fa4\u7814\u7a76\u7684\u9700\u6c42\u3002\u8fd1\u5e74\u6765\uff0c\u7531\u4e8e\u4e00\u7cfb\u5217\u65b0\u6280\u672f\u7684\u8fdb\u6b65\uff0c\u6838\u9178\u67d3\u8272\u8fd9\u79cd\u7ecf\u5178\u7684\u6210\u50cf\u7b56\u7565\u4e5f\u8fce\u6765\u4e86\u590d\u5174\u3002\u6b64\u5916\uff0c\u5c3d\u7ba1\u5728\u8bb8\u591a\u7684\u80a0\u9053\u5171\u751f\u7ec6\u83cc\u4e2d\u8fdb\u884c\u57fa\u56e0\u64cd\u4f5c\u5b58\u5728\u6781\u5927\u7684\u56f0\u96be\uff0c\u4f46\u79d1\u5b66\u754c\u6700\u8fd1\u5728\u5229\u7528\u8367\u5149\u86cb\u767d\u548c\u58f0\u54cd\u5e94\u86cb\u767d\u7b49\u62a5\u544a\u57fa\u56e0\u6765\u6539\u9020\u80a0\u9053\u7ec6\u83cc\u65b9\u9762\u4e5f\u505a\u51fa\u4e86\u5de8\u5927\u7684\u52aa\u529b\u3002\u6700\u540e\uff0c\u6587\u7ae0\u8fd8\u4ecb\u7ecd\u4e86\u5bf9\u8fd9\u4e00\u65b0\u5174\u9886\u57df\u5f53\u524d\u7684\u5c40\u9650\u6027\u4ee5\u53ca\u53d1\u5c55\u8d8b\u52bf\u7684\u770b\u6cd5\u3002\u8be5\u6210\u679c\u4ee5\u9898\u4e3a<strong>\u201c<\/strong><strong>Imaging Commensal Microbiota and Pathogenic Bacteria in the Gut<\/strong><strong>\u201d<\/strong>\u53d1\u8868\u5728<strong><b>Acc. Chem. Res.<\/b><\/strong><strong>\u4e0a<\/strong>\u3002<\/p>\n<p><strong><b>\u3010\u56fe\u6587\u5bfc\u8bfb\u3011<\/b><\/strong><\/p>\n<p><strong><b>Fig<\/b><\/strong><strong>u<\/strong><strong><b>r<\/b><\/strong><strong>e 1.\u7528\u4e8e\u7814\u7a76\u80a0\u9053\u7ec6\u83cc\u7684\u6210\u50cf\u5de5\u5177\u4e3b\u8981\u5305\u62ec\u6297\u751f\u7d20\u884d\u751f\u7684\u8367\u5149\u63a2\u9488\u3001\u4ee3\u8c22\u6807\u8bb0\u63a2\u9488\u3001\u6838\u9178\u67d3\u8272\u63a2\u9488\u548c\u57fa\u56e0\u7f16\u7801\u7684\u62a5\u544a\u57fa\u56e0<\/strong><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-221500\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2021\/05\/r1-2.jpg\" alt=\"\" width=\"600\" height=\"407\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2021\/05\/r1-2.jpg 600w, \/\/m.iemloyee.com\/wp-content\/uploads\/2021\/05\/r1-2-300x204.jpg 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/p>\n<p>\uff08a\uff09\u4e07\u53e4\u9709\u7d20\uff08Vanco\uff09\u884d\u751f\u7684\u8367\u5149\u63a2\u9488\u9776\u5411\u9769\u5170\u6c0f\u9633\u6027\u83cc\u7ec6\u80de\u58c1\u80bd\u805a\u7cd6\u4e2d\u7684D-Ala-D-Ala\u7ed3\u6784\uff0c\u591a\u7c98\u83cc\u7d20B\uff08PxB\uff09\u548c\u5341\u4e09\u78b3\u7d20A\uff08TriA\uff09\u884d\u751f\u7684\u8367\u5149\u63a2\u9488\u5219\u5206\u522b\u7ed3\u5408\u5230\u9769\u5170\u6c0f\u9634\u6027\u83cc\u7684\u8102\u591a\u7cd6\u548c\u8102\u8d28II\u7ed3\u6784\u4e0a\u3002\uff08b\uff09\u8367\u5149D-\u6c28\u57fa\u9178\u63a2\u9488\uff08FDAA\uff09\u53ef\u901a\u8fc7\u7ec6\u83cc\u8f6c\u80bd\u9176\u4ee3\u8c22\u63ba\u5165\u5230\u80bd\u805a\u7cd6\u4e94\u80bd\u7ed3\u6784\u672b\u7aef\u3002\u643a\u5e26\u751f\u7269\u6b63\u4ea4\u57fa\u56e2\u7684\u975e\u5929\u7136\u7cd6\u53ef\u901a\u8fc7\u8865\u6551\u5408\u6210\u9014\u5f84\u6574\u5408\u5230\u7ec6\u83cc\u8868\u9762\u7684\u591a\u7cd6\u7ed3\u6784\u4e2d\uff0c\u968f\u540e\u5229\u7528\u70b9\u51fb\u5316\u5b66\u8fdb\u884c\u8367\u5149\u6807\u8bb0\u6210\u50cf\u3002\u80a0\u9053\u83cc\u7fa4\u89c5\u98df\u5e26\u6709\u540c\u4f4d\u7d20\u6807\u8bb0\u7684\u5bbf\u4e3b\u7c98\u86cb\u767d\u540e\uff0c\u53ef\u88ab\u8d28\u8c31\u6210\u50cf\u3002\uff08c\uff09\u4e5f\u53ef\u4f7f\u7528\u6838\u9178\u67d3\u8272\u63a2\u9488\uff08\u4f8b\u5982DAPI\u67d3\u8272\u548cFISH\u8367\u5149\u63a2\u9488\uff09\u5bf9\u80a0\u9053\u7ec6\u83cc\u8fdb\u884c\u6210\u50cf\u3002\uff08d\uff09\u6216\u8005\u5229\u7528\u9057\u4f20\u64cd\u4f5c\u5de5\u5177\u4f7f\u80a0\u9053\u7ec6\u83cc\u8868\u8fbe\u8367\u5149\u86cb\u767d\u3001\u8367\u5149\u7d20\u9176\u6216\u8005\u6c14\u6ce1\uff0c\u6765\u5bf9\u80a0\u9053\u7ec6\u83cc\u8fdb\u884c\u8367\u5149\u6210\u50cf\u6216\u8d85\u58f0\u6210\u50cf\u3002<\/p>\n<p><strong><b>Figure 2.\u6297\u751f\u7d20\u884d\u751f\u7684\u8367\u5149\u63a2\u9488\u7528\u4e8e\u6210\u50cf\u80a0\u9053\u83cc\u7fa4<\/b><\/strong><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-221501\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2021\/05\/r2-2.jpg\" alt=\"\" width=\"600\" height=\"666\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2021\/05\/r2-2.jpg 600w, \/\/m.iemloyee.com\/wp-content\/uploads\/2021\/05\/r2-2-270x300.jpg 270w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/p>\n<p>\uff08a-b\uff09\u4e07\u53e4\u9709\u7d20\uff08Vanco\uff09\u548c\u591a\u7c98\u83cc\u7d20B\uff08PxB\uff09\u8367\u5149\u884d\u751f\u7269\u7684\u7ed3\u6784\u5f0f\u3002\uff08c\uff09PxB-Cy3\u63a2\u9488\uff08\u7eff\u8272\uff09\u548cVanco-Cy5\u63a2\u9488\uff08\u7ea2\u8272\uff09\u5206\u522b\u9776\u5411\u6807\u8bb0\u5c0f\u9f20\u80a0\u9053\u83cc\u7fa4\u7684\u9634\u6027\u83cc\u548c\u9633\u6027\u83cc\u3002\uff08d\uff09\u5341\u4e09\u78b3\u7d20A\uff08TriA\uff09\u8367\u5149\u884d\u751f\u7269\u7684\u7ed3\u6784\u5f0f\u3002\uff08e\uff09TriA-TAMRA\uff08\u7ea2\u8272\uff09\u548cVanco-BODIPY\uff08\u7eff\u8272\uff09\u5206\u522b\u6807\u8bb0\u5c0f\u9f20\u80a0\u9053\u83cc\u7fa4\u7684\u9634\u6027\u83cc\u548c\u9633\u6027\u83cc\u3002<\/p>\n<p><strong><b>Figure 3.FDAA\u7684\u4ee3\u8c22\u6807\u8bb0\u63a2\u9488\u7528\u4e8e\u6210\u50cf\u80a0\u9053\u7ec6\u83cc<\/b><\/strong><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-221503\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2021\/05\/r3-2.jpg\" alt=\"\" width=\"600\" height=\"427\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2021\/05\/r3-2.jpg 600w, \/\/m.iemloyee.com\/wp-content\/uploads\/2021\/05\/r3-2-300x214.jpg 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/p>\n<p>\uff08a\uff09FDAA\u63a2\u9488\u5728\u7ec6\u83cc\u7ec6\u80de\u58c1\u7684\u5408\u6210\u4ee3\u8c22\u8fc7\u7a0b\u4e2d\u63ba\u5165\u5230\u80bd\u805a\u7cd6\u4e94\u80bd\u7ed3\u6784\u672b\u7aef\u3002\uff08b\uff09\u8367\u5149\u6210\u50cf\u89c2\u5bdf\u5c0f\u9f20\u7ed3\u80a0\u7ec4\u7ec7\u5207\u7247\u4e2dHADA\u6807\u8bb0\u7684\u7caa\u80a0\u7403\u83cc\u3002\uff08c\uff09\u4e24\u79cdFDAA\u8367\u5149\u7684\u6807\u8bb0\u60c5\u51b5\u53cd\u6620\u4e86\u7caa\u83cc\u79fb\u690d\u540e\u690d\u5165\u83cc\u7684\u5b58\u6d3b\u60c5\u51b5\u3002\uff08d\uff09STAMP\u6807\u8bb0\u7b56\u7565\u4e0eFISH\u67d3\u8272\u76f8\u7ed3\u5408\u53ef\u4ee5\u63ed\u793a\u5c0f\u9f20\u4e0d\u540c\u80a0\u9053\u7ec6\u83cc\u5728\u4f53\u539f\u4f4d\u7684\u751f\u957f\u5206\u88c2\u6a21\u5f0f\u3002\uff08e\uff09FDAA\u7684\u8367\u5149\u6807\u8bb0\u5f3a\u5ea6\uff08\u7ea2\u8272\u7ebf\uff09\u4e0e\u6a21\u5f0f\u83cc\u682a\u7684\u751f\u957f\u4ee3\u8c22\u6c34\u5e73\uff08\u84dd\u8272\u7ebf\uff09\u9ad8\u5ea6\u76f8\u5173\u3002\uff08f\uff09\u5c06\u8fd1\u7ea2\u5916\u4e8c\u533a\u8367\u5149\u8fde\u63a5\u7684D-\u578b\u6c28\u57fa\u9178\uff08DAA-NIR-II\uff09\u63a2\u9488\u6807\u8bb0\u7684\u6c99\u95e8\u6c0f\u83cc\u79fb\u690d\u5230\u5c0f\u9f20\u80a0\u9053\u4e2d\uff0c\u53ef\u6d3b\u4f53\u6210\u50cf\u89c2\u5bdf\u6c99\u95e8\u6c0f\u83cc\u5728\u80a0\u9053\u4e2d\u7684\u6d3b\u52a8\u8f68\u8ff9\u3002\uff08g\uff093D\u91cd\u6784\u7ed3\u679c\u663e\u793a\u690d\u5165\u83cc\uff08\u7ea2\u8272\/\u84dd\u8272\uff09\u5728\u80a0\u9053\u7ec4\u7ec7\u4e0a\u7684\u751f\u7269\u5730\u7406\u4fe1\u606f\u3002<\/p>\n<p><strong><b>Figure 4.\u5176\u4ed6\u4ee3\u8c22\u6807\u8bb0\u7b56\u7565\u7528\u4e8e\u6210\u50cf\u80a0\u9053\u7ec6\u83cc<\/b><\/strong><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-221504\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2021\/05\/r4-3.jpg\" alt=\"\" width=\"600\" height=\"583\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2021\/05\/r4-3.jpg 600w, \/\/m.iemloyee.com\/wp-content\/uploads\/2021\/05\/r4-3-300x292.jpg 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/p>\n<p>\uff08a\uff09\u5c06\u643a\u5e26\u751f\u7269\u6b63\u4ea4\u57fa\u56e2\u7684\u975e\u5929\u7136\u6c28\u57fa\u9178\u4ee3\u8c22\u63ba\u5165\u57fa\u56e0\u5de5\u7a0b\u6539\u9020\u7684\u5927\u80a0\u6746\u83cc\u7684\u8868\u9762\u86cb\u767d\uff0c\u8fde\u63a5\u8367\u5149\u56e2\u540e\uff0c\u53ef\u6210\u50cf\u8ffd\u8e2a\u80a0\u9053\u4e2d\u7684\u5927\u80a0\u6746\u83cc\u3002\uff08b-c\uff09\u5229\u7528\u4ee3\u8c22\u5be1\u7cd6\u5de5\u7a0b(MOE)\u5bf9\u80a0\u9053\u7ec6\u83cc\u8fdb\u884c\u6210\u50cf\u3002\uff08d\uff09RNA\u63a2\u9488\u4ee3\u8c22\u6807\u8bb0\u80a0\u9053\u7ec6\u83cc\u65b0\u5408\u6210\u7684RNA\u3002\uff08e\uff09NanoSIMS\u6210\u50cf\u89c5\u98df\u4e86\u540c\u4f4d\u7d20\u6807\u8bb0\u7684\u5bbf\u4e3b\u9ecf\u86cb\u767d\u7684\u80a0\u9053\u7ec6\u83cc\u3002<\/p>\n<p><strong><b>Figure 5.\u6838\u9178\u67d3\u8272\u7528\u4e8e\u6210\u50cf\u80a0\u9053\u83cc\u7fa4<\/b><\/strong><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-221505\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2021\/05\/r5-1.jpg\" alt=\"\" width=\"600\" height=\"630\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2021\/05\/r5-1.jpg 600w, \/\/m.iemloyee.com\/wp-content\/uploads\/2021\/05\/r5-1-286x300.jpg 286w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/p>\n<p>\uff08a\uff09\u5229\u7528DAPI\u67d3\u8272\u6210\u50cf\u5c0f\u9f20\u80a0\u8154\u4e2d\u7684\u80a0\u9053\u7ec6\u83cc\u3002\uff08b\uff09\u57fa\u4e8eCLASI-FISH\u7b56\u7565\u540c\u65f6\u6210\u50cf\u89c2\u5bdf\u80a0\u9053\u5207\u7247\u4e0a15\u79cd\u80a0\u9053\u7ec6\u83cc\u7684\u7a7a\u95f4\u5206\u5e03\u3002\uff08c\uff09\u6539\u8fdb\u7684HiPR-FISH\u7b56\u7565\u80fd\u591f\u540c\u65f6\u6210\u50cf\u80a0\u9053\u4e2d1024\u79cd\u80a0\u9053\u7ec6\u83cc\u3002<\/p>\n<p><strong><b>Figure 6.\u9057\u4f20\u64cd\u4f5c\u5de5\u5177\u7528\u4e8e\u6210\u50cf\u80a0\u9053\u7ec6\u83cc<\/b><\/strong><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-221506\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2021\/05\/r6-1.jpg\" alt=\"\" width=\"600\" height=\"333\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2021\/05\/r6-1.jpg 600w, \/\/m.iemloyee.com\/wp-content\/uploads\/2021\/05\/r6-1-300x167.jpg 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/p>\n<p>\uff08a\uff09\u6784\u5efa\u5408\u6210\u751f\u7269\u5b66\u5e73\u53f0\uff0c\u5bf9\u5b9a\u6b96\u5728\u5c0f\u9f20\u80a0\u9053\u4e2d\u76846\u79cd\u62df\u6746\u83cc\u5c5e\u83cc\u682a\u8fdb\u884c\u6210\u50cf\u3002\uff08b\uff09\u5229\u7528\u57fa\u56e0\u5de5\u7a0b\u6280\u672f\u4f7f\u5927\u80a0\u6746\u83cc\u5f62\u6210\u5145\u6c14\u7684\u86cb\u767d\u8d28\u7eb3\u7c73\u7ed3\u6784\uff08\u6c14\u6ce1\uff09\u6765\u53cd\u5c04\u8d85\u58f0\u6ce2\uff0c\u8fdb\u800c\u8d85\u58f0\u6210\u50cf\u5c0f\u9f20\u4f53\u5185\u7684\u5927\u80a0\u6746\u83cc\u3002\uff08c\uff09MAGIC\u7b56\u7565\u901a\u8fc7\u64cd\u7eb5\u79fb\u52a8\u57fa\u56e0\u5143\u4ef6\u5e93\uff0c\u53ef\u5bf9\u54fa\u4e73\u52a8\u7269\u80a0\u9053\u83cc\u7fa4\u8fdb\u884c\u539f\u4f4d\u57fa\u56e0\u64cd\u4f5c\u3002<\/p>\n<p><strong><b>\u3010<\/b><\/strong><strong><b>\u5c0f\u7ed3<\/b><\/strong><strong><b>\u3011<\/b><\/strong><\/p>\n<p>\u5728\u8fd9\u7bc7\u7efc\u8ff0\u4e2d\uff0c<strong><b>\u4e0a\u6d77\u4ea4\u901a\u5927\u5b66<\/b><\/strong><strong><b>\u533b\u5b66\u9662\u6768\u671d\u52c7<\/b><\/strong><strong><b>&amp;<\/b><\/strong><strong><b>\u738b\u709c<\/b><\/strong>\u91cd\u70b9\u4ecb\u7ecd\u4e86\u5176\u56e2\u961f\u548c\u5176\u4ed6\u8bfe\u9898\u7ec4\u5728\u8fc7\u53bb\u4e94\u5e74\u4e2d\u5f00\u53d1\u7684\u5bf9\u80a0\u9053\u5171\u751f\u548c\u81f4\u75c5\u6027\u7ec6\u83cc\u8fdb\u884c\u6210\u50cf\u7684\u5316\u5b66\u751f\u7269\u5b66\u5de5\u5177\u548c\u65b0\u65b9\u6cd5\uff0c\u5e76\u63d0\u4f9b\u4e86\u5bf9\u8fd9\u4e00\u7814\u7a76\u9886\u57df\u4e2d\u7684\u6311\u6218\u548c\u8d8b\u52bf\u7684\u770b\u6cd5\u3002<\/p>\n<p><strong><b>\u6587\u732e\u94fe\u63a5<\/b><\/strong>\uff1aImaging Commensal Microbiota and Pathogenic Bacteria in the Gut, <strong><b>Acc. Chem. Res.<\/b><\/strong>,<em>\u00a0<\/em>2021, DOI:10.1021\/acs.accounts.1c00068<\/p>\n<p>\u672c\u6587\u7531\u6750\u6599\u4eba\u5b66\u672f\u7ec4tt\u4f9b\u7a3f\uff0c\u6750\u6599\u725b\u6574\u7406\u7f16\u8f91\u3002 \u00a0<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u3010\u5f15\u8a00\u3011 \u4f5c\u4e3a\u4e00\u4e2a\u65b0\u53d1\u73b0\u7684\u5668\u5b98\uff0c\u5728\u8fc7\u53bb\u7684\u4e8c\u5341\u5e74\u4e2d\uff0c\u80a0\u9053\u83cc\u7fa4\u5f97\u5230\u4e86\u5e7f\u6cdb\u7684\u7814\u7a76\uff0c\u5b83\u4eec\u5728\u5bbf\u4e3b\u4f17\u591a\u5668\u5b98\u548c\u7cfb\u7edf\u7684\u751f\u7406\u75c5\u7406\u8fc7\u7a0b\u4e2d\u7684\u9ad8\u5ea6\u591a\u6837\u5316\u548c\u57fa\u7840\u6027\u7684\u4f5c\u7528\u9010\u6e10\u88ab\u63ed\u793a\u3002\u4f46\u662f\uff0c&#8230;<\/p>\n","protected":false},"author":7336,"featured_media":221500,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[215],"tags":[4344],"class_list":["post-221499","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-jiedu","tag-4344"],"_links":{"self":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts\/221499"}],"collection":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/users\/7336"}],"replies":[{"embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=221499"}],"version-history":[{"count":2,"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts\/221499\/revisions"}],"predecessor-version":[{"id":221944,"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts\/221499\/revisions\/221944"}],"wp:featuredmedia":[{"embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/media\/221500"}],"wp:attachment":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=221499"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=221499"},{"taxonomy":"post_tag","embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=221499"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}