{"id":220995,"date":"2021-04-29T06:29:25","date_gmt":"2021-04-28T22:29:25","guid":{"rendered":"\/\/m.iemloyee.com\/?p=220995"},"modified":"2021-04-28T21:31:37","modified_gmt":"2021-04-28T13:31:37","slug":"%e4%b8%80%e6%9c%88%e4%b8%a4%e7%af%87nature%e7%b3%bb%e5%88%97%e9%a1%b6%e5%88%8a-%e6%ae%b5%e9%95%b6%e9%94%8b%e3%80%81%e6%bd%98%e9%94%8b%e3%80%81%e7%94%b3%e6%9c%89%e9%9d%92%e7%ad%89%e8%bf%91","status":"publish","type":"post","link":"\/\/m.iemloyee.com\/?p=220995","title":{"rendered":"\u4e00\u6708\u4e24\u7bc7Nature\u7cfb\u5217\u9876\u520a\u2014\u6bb5\u9576\u950b\u3001\u6f58\u950b\u3001\u7533\u6709\u9752\u7b49\u8fd1\u671f\u6210\u679c\u6c47\u603b"},"content":{"rendered":"<p><strong><b>\u6d59\u5927<\/b><\/strong><strong><b>N<\/b><\/strong><strong><b>at.<\/b><\/strong><strong><b>\u00a0C<\/b><\/strong><strong><b>ommun.\uff1a\u7b49\u79bb\u5b50\u7eb3\u7c73\u53cd\u5e94\u5668<\/b><\/strong><\/p>\n<p>\u5728\u5316\u7597-\u514d\u75ab\u8054\u5408\u7597\u6cd5\u4e2d\uff0c\u4eba\u4eec\u5e38\u7528\u4f4e\/\u6807\u51c6\u5242\u91cf\u7684\u5316\u7597\u6765\u907f\u514d\u5316\u7597\u8bf1\u5bfc\u7684\u9aa8\u9ad3\u6291\u5236\u548c\u5bf9\u4e3b\u4f53\u514d\u75ab\u7cfb\u7edf\u7684\u7834\u574f\u3002\u56e0\u6b64\uff0c\u5728\u8054\u5408\u6cbb\u7597\u4e2d\uff0c\u5982\u4f55\u5728\u4f4e\u5316\u7597\u5242\u91cf\u4e0b\u8bf1\u5bfc\u514d\u75ab\u539f\u6027\u7ec6\u80de\u6b7b\u4ea1\uff08\u7279\u522b\u662f\u5728\u8010\u836f\u764c\u7ec6\u80de\u4e2d\uff09\uff0c\u5c31\u6210\u4e3a\u5b9e\u73b0\u9ad8\u6548\u5316\u7597-\u514d\u75ab\u8054\u5408\u6cbb\u7597\u7684\u5173\u952e\u3002\u53e6\u5916\uff0c\u7531\u4e8e\u6297\u4f53\u7684\u80bf\u7624\u7a7f\u900f\u80fd\u529b\u8f83\u5dee\uff0c\u5982\u4f55\u63d0\u5347PD-1\/PD-L1\u7684\u6291\u5236\u6548\u7387\u4e5f\u662f\u63d0\u9ad8\u514d\u75ab\u68c0\u67e5\u70b9\u6291\u5236\u7597\u6cd5\u7684\u91cd\u8981\u8bfe\u9898\u3002<\/p>\n<p><strong><b><img 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loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-221334\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2021\/04\/\u56fe\u7247-3-13.png\" alt=\"\" width=\"600\" height=\"420\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2021\/04\/\u56fe\u7247-3-13.png 600w, \/\/m.iemloyee.com\/wp-content\/uploads\/2021\/04\/\u56fe\u7247-3-13-300x210.png 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/b><\/strong><\/p>\n<p style=\"text-align: center;\"><strong><b>OPDEA-PSN38\u80f6\u675f\u7684\u80bf\u7624\u4e3b\u52a8\u6e17\u900f\u673a\u7406\u793a\u610f\u56fe<\/b><\/strong><\/p>\n<p><strong><b>\u6d59\u6c5f\u5927\u5b66\u7533\u6709\u9752<\/b><\/strong>\uff08\u901a\u8baf\u4f5c\u8005\uff09\u56e2\u961f\u5728\u524d\u671f\u5de5\u4f5c\u7684\u57fa\u7840\u4e0a\uff0c\u6210\u529f\u8bbe\u8ba1\u5408\u6210\u4e86\u4e00\u79cd\u542b\u6709\u4e09\u7ea7\u80fa\u6c2e\u6c27\u7ed3\u6784\u7684\u4e24\u6027\u79bb\u5b50\u805a\u5408\u7269OPDEA\uff0c\u4e00\u65b9\u9762\uff0c\u5b83\u8868\u73b0\u51fa\u4e86\u4e0d\u4e0e\u86cb\u767d\u8d28\u5438\u9644\u800c\u4e0e\u7ec6\u80de\u819c\u53ef\u9006\u5438\u9644\u7684\u5438\u9644\u9009\u62e9\u6027\uff0c\u4ece\u800c\u201c\u9690\u853d\u201d\u5728\u8840\u6db2\u5faa\u73af\u7cfb\u7edf\u4e2d\u5b9e\u73b0\u957f\u5faa\u73af\u548c\u80bf\u7624\u5bcc\u96c6\uff1b\u53e6\u4e00\u65b9\u9762\uff0c\u5b83\u7684\u7ec6\u80de\u819c\u9009\u62e9\u6027\u5438\u9644\u53ef\u4fc3\u4f7f\u5176\u5feb\u901f\u5730\u88ab\u80bf\u7624\u8840\u7ba1\u5185\u76ae\u7ec6\u80de\u548c\u80bf\u7624\u7ec6\u80de\u6444\u53d6\uff0c\u4ece\u800c\u89e6\u53d1\u4e3b\u52a8\u8f6c\u80de\u541e\u4f5c\u7528\u5e76\u5b9e\u73b0\u9ad8\u6548\u7684\u80bf\u7624\u8840\u7ba1\u5916\u6e17\u548c\u80bf\u7624\u4e3b\u52a8\u6e17\u900f\u3002\u57fa\u4e8e\u8fd9\u4e00\u6750\u6599\uff0c\u7814\u7a76\u5236\u5907\u4e86\u4ee5OPDEA\u4e3a\u4eb2\u6c34\u5916\u5c42\u3001\u4ee5\u5316\u7597\u836f\u72697-\u4e59\u57fa-10-\u7f9f\u57fa\u559c\u6811\u78b1\uff08SN38\uff09\u524d\u836f\u805a\u5408\u7269\u4e3a\u758f\u6c34\u5185\u6838\u7684\u7eb3\u7c73\u8f7d\u836f\u80f6\u675f\uff08OPDEA-PSN38\uff09\u3002\u8be5\u80f6\u675f\u5728\u7ecf\u8fc7\u5c3e\u9759\u8109\u6ce8\u5c04\u540e\u80fd\u591f\u53ef\u9006\u5730\u5438\u9644\u5230\u7ea2\u7ec6\u80de\u4e0a\uff0c\u5e76\u7ee7\u800c\u5f31\u5438\u9644\u5728\u80bf\u7624\u8840\u7ba1\u5185\u76ae\u7ec6\u80de\u4e0a\u5e76\u89e6\u53d1\u5176\u8f6c\u80de\u541e\u4f5c\u7528\u3002\u8be5\u7eb3\u7c73\u836f\u7269\u5728\u591a\u79cd\u8377\u7624\u5c0f\u9f20\u6a21\u578b\uff08\u5305\u62ec\u809d\u764c\u539f\u4f4d\u6a21\u578b\u548c\u4eba\u6e90\u80bf\u7624\u5f02\u79cd\u79fb\u690d\u7624\u6a21\u578b\uff09\u4e2d\u5747\u8868\u73b0\u51fa\u4f18\u5f02\u7684\u6291\u7624\u4f5c\u7528\uff0c\u5728\u5e38\u89c4\u7ed9\u836f\u5242\u91cf\u4e0b\uff0c\u5b83\u4e0d\u4ec5\u80fd\u6e05\u9664\u8d77\u59cb\u80bf\u7624\u5927\u5c0f\u4e3a70 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width=\"600\" height=\"331\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2021\/04\/\u56fe\u7247-5-11.png 600w, \/\/m.iemloyee.com\/wp-content\/uploads\/2021\/04\/\u56fe\u7247-5-11-300x166.png 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/b><\/strong><\/p>\n<p style=\"text-align: center;\"><strong><b>\u5408\u6210\u5377\u66f2\u7ed3\u6784\u793a\u610f\u56fe<\/b><\/strong><\/p>\n<p><strong><b>\u6e56\u5357<\/b><\/strong><strong><b>\u5927\u5b66<\/b><\/strong><strong><b>\u7684\u6bb5\u66e6\u4e1c\u548c\u52a0\u5dde\u5927\u5b66\u6d1b\u6749\u77f6\u5206\u6821\u7684\u6bb5\u9576\u950b<\/b><\/strong>\uff08\u5171\u540c\u901a\u8baf\u4f5c\u8005\uff09\u8054\u5408\u63d0\u51fa\u4e86\u4e00\u79cd\u901a\u8fc7\u5377\u66f2\u8303\u5fb7\u534e\u5f02\u8d28\u7ed3\u6784\u6765\u5b9e\u73b0\u9ad8\u9636\u8303\u5fb7\u534e\u8d85\u6676\u683c\u7684\u76f4\u63a5\u65b9\u6cd5\u3002\u7814\u7a76\u5c06CVD\u751f\u957f\u7684SnS<sub>2<\/sub>\/WSe<sub>2<\/sub>\u8303\u5fb7\u534e\u5f02\u8d28\u7ed3\u66b4\u9732\u5728\u4e59\u9187-\u6c34-\u6c28\u6df7\u5408\u6eb6\u6db2\u4e2d\uff0c\u5229\u7528\u6bdb\u7ec6\u4f5c\u7528\u529b\uff0c\u9a71\u52a8\u5f02\u8d28\u7ed3\u4e0e\u886c\u5e95\u5206\u79bb\u5e76\u53d1\u751f\u81ea\u53d1\u5377\u66f2\u884c\u4e3a\uff0c\u4ece\u800c\u6210\u529f\u6784\u5efa\u9ad8\u9636\u4e8c\u7ef4\u8d85\u6676\u683c\u3002\u8fd9\u7c7b\u8d85\u6676\u683c\u7684\u5f62\u6210\u80fd\u591f\u8c03\u8282\u7535\u5b50\u80fd\u5e26\u7ed3\u6784\u53ca\u5176\u7ef4\u5ea6\uff0c\u5bfc\u81f4\u8f93\u8fd0\u7279\u6027\u53d1\u751f\u534a\u5bfc\u4f53-\u91d1\u5c5e\u8f6c\u53d8\uff0c\u5e76\u4ea7\u751f\u89d2\u5ea6\u4f9d\u8d56\u7684\u7ebf\u6027\u78c1\u81f4\u7535\u963b\u6548\u5e94\u3002\u8fd9\u4e00\u7b56\u7565\u53ef\u6269\u5c55\u5236\u5907\u591a\u79cd\u4e8c\u7ef4\/\u4e8c\u7ef4\u8303\u5fb7\u534e\u8d85\u6676\u683c\uff0c\u4ee5\u53ca\u5305\u62ec\u4e09\u7ef4\u8584\u819c\u5728\u5185\u7684\u8d85\u4e8c\u7ef4\u6750\u6599\uff0c\u4ece\u800c\u5f62\u6210\u6df7\u5408\u7ef4\u5ea6\u7684\u8303\u5fb7\u534e\u8d85\u6676\u683c\u3002\u8fd9\u4e00\u7814\u7a76\u9610\u91ca\u4e86\u751f\u4ea7\u9ad8\u9636\u8303\u5fb7\u534e\u8d85\u6676\u683c\u7684\u901a\u7528\u65b9\u6cd5\uff0c\u540c\u65f6\u4e5f\u4e3a\u57fa\u7840\u7814\u7a76\u548c\u6280\u672f\u5e94\u7528\u63d0\u4f9b\u4e86\u4e30\u5bcc\u7684\u6750\u6599\u5e73\u53f0\u3002<\/p>\n<p><strong><b>\u6587\u732e\u94fe\u63a5<\/b><\/strong>\uff1ahttps:\/\/www.nature.com\/articles\/s41586-021-03338-0<\/p>\n<p><strong><b>\u6e56\u5927&amp;<\/b><\/strong><strong><b>UCLA<\/b><\/strong><strong><b>&amp;\u4eba\u5927Nat.<\/b><\/strong><strong><b>\u00a0M<\/b><\/strong><strong><b>ater.\uff1a\u7852\u5316\u94ec\u7eb3\u7c73\u7247\u7684\u5916\u5ef6\u751f\u957f<\/b><\/strong><\/p>\n<p>\u4e8c\u7ef4\u8303\u5fb7\u534e\u6676\u4f53\u4e2d\u5185\u751f\u6027\u94c1\u78c1\u6027\u7684\u53d1\u73b0\u6fc0\u53d1\u4e86\u5bf9\u4e8c\u7ef4\u6781\u9650\u7684\u78c1\u5e8f\u7814\u7a76\uff0c\u5728\u78c1\u6027\u611f\u6d4b\u548c\u4fe1\u606f\u5b58\u50a8\u7b49\u65b9\u9762\u53ef\u80fd\u5177\u6709\u5de8\u5927\u7684\u524d\u666f\u3002\u7136\u800c\uff0c\u76ee\u524d\u5df2\u77e5\u7684\u5927\u591a\u6570\u4e8c\u7ef4\u8303\u5fb7\u534e\u94c1\u78c1\u4f53\u65e0\u6cd5\u5728\u5e73\u5e38\u73af\u5883\u4e2d\u6301\u4e45\u7a33\u5b9a\uff0c\u540c\u65f6\u673a\u68b0\u5265\u79bb\u7b49\u5e38\u89c1\u7684\u5236\u5907\u65b9\u6cd5\u53c8\u4e0d\u5177\u5907\u9ad8\u901a\u91cf\u3001\u6709\u9650\u53ef\u63a7\u7684\u80fd\u529b\u3002\u7531\u4e8e\u8fd9\u7c7b\u94c1\u78c1\u4f53\u7684\u539f\u5b50\u7ea7\u5355\u5c42\u5bf9\u4e8e\u5408\u6210\u8fc7\u7a0b\u6781\u5ea6\u654f\u611f\uff0c\u56e0\u6b64\u76f4\u63a5\u5408\u6210\u8fd9\u7c7b\u78c1\u6027\u6750\u6599\u96be\u5ea6\u975e\u5e38\u5927\u3002<\/p>\n<p><strong><b><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-221336\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2021\/04\/\u56fe\u7247-8-5.png\" alt=\"\" width=\"600\" height=\"341\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2021\/04\/\u56fe\u7247-8-5.png 600w, \/\/m.iemloyee.com\/wp-content\/uploads\/2021\/04\/\u56fe\u7247-8-5-300x171.png 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/b><\/strong><\/p>\n<p style=\"text-align: center;\"><strong><b>\u7852\u5316\u94ec\u7eb3\u7c73\u7247\u7684\u539a\u5ea6\u53ef\u8c03\u5408\u6210<\/b><\/strong><\/p>\n<p><strong><b>\u6e56\u5357\u5927\u5b66\u7684\u6bb5\u66e6\u4e1c\u3001\u4e2d\u56fd\u4eba\u6c11\u5927\u5b66\u7684\u5b63\u5a01\u548c\u52a0\u5dde\u5927\u5b66\u6d1b\u6749\u77f6\u5206\u6821\u7684\u6bb5\u9576\u950b<\/b><\/strong>\uff08\u5171\u540c\u901a\u8baf\u4f5c\u8005\uff09\u7b49\u4eba\u5c55\u793a\u4e86\u53ef\u5728\u65e0\u60ac\u6302\u952e\u7684\u7852\u5316\u94a8\u886c\u5e95\u4e0a\u8f7b\u677e\u751f\u957f\u73af\u5883\u7a33\u5b9a\u6027\u5f3a\u7684\u7852\u5316\u94ec\u7eb3\u7c73\u7247\u3002\u7531\u6b64\u751f\u957f\u7684\u7852\u5316\u94ec\u539a\u5ea6\u53ef\u8c03\u539a\u5ea6\u53ef\u8c03\uff0c\u6700\u4f4e\u53ef\u8c03\u81f3\u5355\u5c42\u6781\u9650\u3002\u8fd9\u4e9b\u7852\u5316\u94ec\/\u7852\u5316\u94a8\u5f02\u8d28\u7ed3\u6784\u754c\u9762\u5177\u6709\u8d85\u5206\u8fa8\u7684\u6469\u5c14\u8d85\u6676\u683c\uff0c\u540c\u65f6\u8fd8\u5c55\u73b0\u51fa\u4e86\u53ef\u89c2\u7684\u94c1\u78c1\u884c\u4e3a\u3002\u4e0d\u4ec5\u5982\u6b64\uff0c\u7814\u7a76\u8fd8\u53d1\u73b0\uff0c\u66b4\u9732\u5728\u7a7a\u6c14\u4e2d\u957f\u8fbe\u6570\u6708\u4e4b\u540e\uff0c\u8be5\u7eb3\u7c73\u7247\u7684\u8868\u9762\u7c97\u7cd9\u5ea6\u548c\u78c1\u6027\u6027\u8d28\u6ca1\u6709\u663e\u8457\u53d8\u5316\u3002\u8ba1\u7b97\u7814\u7a76\u8868\u660e\uff0c\u6765\u81ea\u7852\u5316\u94a8\u886c\u5e95\u548c\u4e0e\u7852\u5316\u94ec\u5939\u5c42\u7684\u7535\u8377\u8f6c\u79fb\u5728\u7eb3\u7c73\u7247\u78c1\u5e8f\u4e2d\u626e\u6f14\u8005\u91cd\u8981\u7684\u89d2\u8272\u3002\u7814\u7a76\u8ba4\u4e3a\uff0c\u9ad8\u5ea6\u53ef\u63a7\u3001\u539a\u5ea6\u53ef\u8c03\u7684\u7852\u5316\u94ec\u7eb3\u7c73\u7247\u4e3a\u57fa\u7840\u7814\u7a76\u63d0\u4f9b\u4e86\u7406\u60f3\u7684\u7814\u7a76\u5bf9\u8c61\uff0c\u4e5f\u5728\u78c1\u7535\u3001\u81ea\u65cb\u5668\u4ef6\u9886\u57df\u5c55\u73b0\u51fa\u4e86\u5e94\u7528\u524d\u666f\u3002<\/p>\n<p><strong><b>\u6587\u732e\u94fe\u63a5<\/b><\/strong>\uff1ahttps:\/\/www.nature.com\/articles\/s41563-021-00927-2<strong><b>\u00a0<\/b><\/strong><\/p>\n<p><strong><b>\u5317\u5927&amp;\u7f8e\u56fd\u9646\u519b\u7814\u7a76\u5b9e\u9a8c\u5ba4Nat.<\/b><\/strong><strong><b>\u00a0N<\/b><\/strong><strong><b>naotech.\uff1a\u94b4\u9178\u9502\u6b63\u6781\u6750\u6599\u7684\u7ed3\u6784\u7814\u7a76<\/b><\/strong><\/p>\n<p>\u9502\u7535\u6c60\u4f5c\u4e3a\u65b0\u4e00\u4ee3\u7eff\u8272\u50a8\u80fd\u5668\u4ef6\u5728\u65e5\u5e38\u751f\u6d3b\u4e2d\u626e\u6f14\u7740\u91cd\u8981\u7684\u89d2\u8272\uff0c\u8fd1\u671f\u9488\u5bf9\u94b4\u9178\u9502\u6b63\u6781\u7684\u6027\u80fd\u63d0\u5347\u7814\u7a76\u66f4\u662f\u53d1\u5c55\u8fc5\u901f\u3002\u4f46\u662f\uff0c\u8fd9\u4e9b\u7814\u7a76\u65e0\u6cd5\u4ece\u7ed3\u6784\u89d2\u5ea6\uff08\u8fd9\u4e9b\u6750\u6599\u7684X-\u5c04\u7ebf\u884d\u5c04\u6ca1\u6709\u660e\u663e\u7684\u5dee\u522b\uff09\u7ed9\u51fa\u94b4\u9178\u9502\u7a33\u5b9a\u6027\u63d0\u5347\u7684\u6839\u672c\u539f\u56e0\uff0c\u56e0\u6b64\u94b4\u9178\u9502\u5728\u9ad8\u7535\u538b\u4e0b\u7684\u6027\u80fd\u6539\u8fdb\u65b9\u5411\u4ecd\u4e0d\u660e\u6717\u3002\u73b0\u6709\u7684\u8868\u5f81\u6280\u672f\u5982X\u5c04\u7ebf\u884d\u5c04\u7b49\u96be\u4ee5\u63ed\u793a\u4e0e\u6027\u80fd\u76f8\u5173\u7684\u5fae\u89c2\u7ed3\u6784\u7ec6\u8282\uff1b\u540c\u65f6\u4ec5\u80fd\u53cd\u6620\u67d0\u4e2a\u5fae\u533a\u800c\u65e0\u6cd5\u7ed9\u51fa\u66f4\u5927\u5c3a\u5ea6\u5982\u5355\u9897\u7c92\u7684\u7ed3\u6784\u4fe1\u606f\u3002<\/p>\n<p><strong><b><img 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