{"id":198245,"date":"2020-03-27T06:05:23","date_gmt":"2020-03-26T22:05:23","guid":{"rendered":"\/\/m.iemloyee.com\/?p=198245"},"modified":"2020-03-26T23:07:15","modified_gmt":"2020-03-26T15:07:15","slug":"%e7%ba%b3%e7%b1%b3%e9%85%b6%ef%bc%8c%e4%b8%8d%e4%b8%80%e6%a0%b7%e7%9a%84%e9%a3%8e%e9%87%87-%e7%ba%b3%e7%b1%b3%e9%85%b6%e6%9c%80%e6%96%b0%e6%88%90%e6%9e%9c%e9%80%9f%e9%80%92","status":"publish","type":"post","link":"\/\/m.iemloyee.com\/?p=198245","title":{"rendered":"\u7eb3\u7c73\u9176\uff0c\u4e0d\u4e00\u6837\u7684\u98ce\u91c7\u00a0\/ \u7eb3\u7c73\u9176\u6700\u65b0\u6210\u679c\u901f\u9012"},"content":{"rendered":"

\u960e\u9521\u8574\uff08\u4e2d\u56fd\u79d1\u5b66\u9662\u751f\u7269\u7269\u7406\u7814\u7a76\u6240\uff09<\/b><\/strong><\/p>\n

1. Nano Letters \u94c1\u86cb\u767d\u7eb3\u7c73\u9176\u4fdd\u62a4\u8840-\u8111\u5c4f\u969c\u7684\u5b8c\u6574\u6027\u62b5\u6297\u759f\u75be<\/strong><\/p>\n

\u8111\u90e8\u759f\u75be\u662f\u4e00\u79cd\u4ee5\u4e2d\u67a2\u795e\u7ecf\u7cfb\u7edf\u529f\u80fd\u969c\u788d\u4e3a\u7279\u5f81\u7684\u759f\u75be\u611f\u67d3\u4ea7\u751f\u7684\u81f4\u6b7b\u6027\u5e76\u53d1\u75c7\uff0c\u901a\u5e38\u4e0d\u80fd\u901a\u8fc7\u6297\u759f\u75be\u8054\u5408\u7597\u6cd5\u5f97\u5230\u6709\u6548\u6cbb\u7597\u3002\u5176\u4e2d\uff0c\u5bf9\u8111\u8840\u7ba1\u5185\u76ae\u7ec6\u80de\u4e0e\u88ab\u5bc4\u751f\u866b\u611f\u67d3\u7684\u7ea2\u7ec6\u80de\u76f8\u4e92\u4f5c\u7528\u7684\u9694\u79bb\u548c\u8840-\u8111\u5c4f\u969c\u7684\u7834\u574f\u5728\u53d1\u75c5\u673a\u7406\u4e2d\u8d77\u5173\u952e\u4f5c\u7528\u3002\u4e2d\u56fd\u79d1\u5b66\u9662\u751f\u7269\u7269\u7406\u7814\u7a76\u6240\u960e\u9521\u8574\u9662\u58eb\u8bfe\u9898\u7ec4\u5f00\u53d1\u4e86\u4e00\u79cd\u7531\u91cd\u7ec4\u4eba\u94c1\u86cb\u767d\u7ec4\u6210\u7684\u94c1\u86cb\u767d\u7eb3\u7c73\u9176\uff0c\u8be5\u94c1\u86cb\u767d\u7eb3\u7c73\u9176\u9488\u5bf9\u8840-\u8111\u5c4f\u969c\u5185\u76ae\u7ec6\u80de\u4ee5\u53ca\u5185\u90e8\u8fc7\u6c27\u5316\u6c22\u9176\u6837\u6d3b\u6027\u7684Fe3<\/sub>O4<\/sub>\u7eb3\u7c73\u9176\u7528\u4e8e\u6e05\u9664\u4f53\u5185\u6d3b\u6027\u6c27\u3002\u5f53\u5bf9\u60a3\u6709\u8111\u90e8\u759f\u75be\u7684\u5c0f\u9f20\u7ed9\u836f\u65f6\uff0c\u94c1\u86cb\u767d\u7eb3\u7c73\u9176\u901a\u8fc7\u4fdd\u62a4\u8840-\u8111\u5c4f\u969c\u5185\u76ae\u7ec6\u80de\u514d\u53d7\u6d3b\u6027\u6c27\u635f\u4f24\u5e76\u901a\u8fc7\u4f7f\u5de8\u566c\u7ec6\u80de\u6781\u5316\u4e3aM1\u578b\uff0c\u4fc3\u8fdb\u8840\u6db2\u4e2d\u759f\u75be\u7684\u6d88\u9664\uff0c\u964d\u4f4e\u5bc4\u751f\u866b\u8840\u75c7\uff0c\u4ece\u800c\u663e\u8457\u63d0\u9ad8\u4e86\u5b58\u6d3b\u7387\u3002\u8be5\u94c1\u86cb\u767d\u7eb3\u7c73\u9176\u663e\u8457\u51cf\u8f7b\u4e86\u7528\u84bf\u7532\u919a\u6cbb\u7597\u7684\u8111\u90e8\u759f\u75be\u5c0f\u9f20\u7684\u8111\u90e8\u708e\u75c7\u548c\u8bb0\u5fc6\u969c\u788d\uff0c\u94c1\u86cb\u767d\u7eb3\u7c73\u9176\u4e0e\u6297\u759f\u75be\u836f\u7269\u8054\u5408\u4f7f\u7528\u4e3a\u6cbb\u7597\u8111\u90e8\u759f\u75be\u63d0\u4f9b\u4e00\u79cd\u7684\u65b0\u7b56\u7565\u3002[1]<\/sup>\u00a0\u76f8\u5173\u7814\u7a76\u4ee5\u201cFenozyme Protects the Integrity of the Blood-Brain Barrier against\u00a0Experimental Cerebral Malaria\u201d\u4e3a\u9898\uff0c\u53d1\u8868\u5728Nano Letters\u3002<\/p>\n

https:\/\/pubs.acs.org\/doi\/abs\/10.1021\/acs.nanolett.9b03774\u00a0<\/p>\n

\u56fe\u4e00\uff1a\u94c1\u86cb\u767d\u7eb3\u7c73\u9176\u4fdd\u62a4\u5c0f\u9f20\u514d\u4e8e\u5b9e\u9a8c\u6027\u8111\u90e8\u759f\u75be\u793a\u610f\u56fe<\/b><\/strong><\/p>\n

\"\"<\/p>\n

2. Angew. Chem. Int. Ed.\u5355\u539f\u5b50\u7eb3\u7c73\u9176\u6297\u83cc<\/strong><\/p>\n

\u5355\u539f\u5b50\u50ac\u5316\u5242\u5df2\u5e7f\u6cdb\u7528\u4e8e\u5316\u5b66\u50ac\u5316\uff0c\u4f46\u5355\u539f\u5b50\u7eb3\u7c73\u9176\u662f\u5426\u5177\u6709\u826f\u597d\u7684\u50ac\u5316\u6d3b\u6027\u5177\u6709\u91cd\u8981\u7814\u7a76\u610f\u4e49\u3002\u4e2d\u56fd\u79d1\u5b66\u9662\u751f\u7269\u7269\u7406\u7814\u7a76\u6240\u960e\u9521\u8574\u9662\u58eb\u8bfe\u9898\u7ec4\u4e0e\u5317\u4eac\u5316\u5de5\u5927\u5b66\u5218\u60e0\u7389\u6559\u6388\u8bfe\u9898\u7ec4\u5408\u4f5c\u63d0\u51fa\u4e86\u542b\u6709\u539f\u5b50\u5206\u6563\u7684\u950c\u539f\u5b50\u7684\u950c\u57fa\u6cb8\u77f3-\u54aa\u5511\u76d0\u9aa8\u67b6\uff08ZIF-8\uff09\u884d\u751f\u7684\u78b3\u7eb3\u7c73\u6750\u6599\u53ef\u4ee5\u7528\u4f5c\u9ad8\u6548\u7684\u5355\u539f\u5b50\u8fc7\u6c27\u5316\u7269\u9176\u6a21\u62df\u7269\u3002\u5b9e\u9a8c\u8bc1\u660e\u8be5\u5355\u539f\u5b50\u7eb3\u7c73\u9176\u5177\u6709\u4e0e\u5929\u7136\u9176\u76f8\u4f3c\u7684\u50ac\u5316\u6d3b\u6027\u548cM-Nx<\/sub>\u6d3b\u6027\u4f4d\u70b9\uff0c\u5176\u4e2d\u9ad8\u50ac\u5316\u6d3b\u6027\u5f52\u56e0\u4e8e\u914d\u4f4d\u4e0d\u9971\u548c\u7684Zn-N4<\/sub>\u6d3b\u6027\u4f4d\u70b9\u3002\u8be5\u5355\u539f\u5b50\u7eb3\u7c73\u9176\u4fc3\u8fdb\u8fc7\u6c27\u5316\u6c22\u5206\u89e3\u548c\u7f9f\u57fa\u81ea\u7531\u57fa\u7684\u5f62\u6210\uff0c\u5bf9\u94dc\u7eff\u5047\u5355\u80de\u83cc\u7684\u6291\u5236\u7387\u9ad8\u8fbe99.87\uff05\uff0c\u5e76\u663e\u7740\u4fc3\u8fdb\u4f24\u53e3\u6108\u5408\u3002\u5728\u4f53\u5185\u611f\u67d3\u7684\u4f24\u53e3\u6a21\u578b\u4e2d\uff0c\u8be5\u5355\u539f\u5b50\u7eb3\u7c73\u9176\u53ef\u663e\u7740\u4fc3\u8fdb\u4f24\u53e3\u6108\u5408\uff0c\u5e76\u5bf9\u5404\u79cd\u7ec4\u7ec7\u548c\u5668\u5b98\u65e0\u660e\u663e\u6bd2\u6027\u3002\u8fd9\u9879\u5de5\u4f5c\u4e3a\u5355\u539f\u5b50\u50ac\u5316\u5242\u5728\u9176\u50ac\u5316\u9886\u57df\u548c\u751f\u7269\u5e94\u7528\u4e2d\u5f00\u8f9f\u4e86\u65b0\u7684\u89c6\u91ce\u3002[2] <\/sup>\u76f8\u5173\u7814\u7a76\u4ee5\u201cSingle-Atom Nanozyme for Wound Antibacterial Applications\u201d\u4e3a\u9898\uff0c\u53d1\u8868\u5728Angew. Chem. Int. Ed.\u3002<\/p>\n

https:\/\/onlinelibrary.wiley.com\/doi\/abs\/10.1002\/anie.201813994\u00a0<\/p>\n

\u56fe\u4e8c\uff1a\u5355\u539f\u5b50\u7eb3\u7c73\u9176\u7528\u4e8e\u4f24\u53e3\u6297\u83cc\u793a\u610f\u56fe<\/b><\/strong><\/p>\n

\"\"<\/p>\n

3. Nano Letters\u8fc7\u6c27\u5316\u6c22\u54cd\u5e94\u578b\u7684\u7eb3\u7c73\u9176\u7528\u4e8e\u9f3b\u54bd\u764c\u5149\u58f0\u6210\u50cf<\/strong><\/p>\n

\u7531\u4e8e\u5176\u5728\u6df1\u5c42\u7ec4\u7ec7\u7a7f\u900f\u548c\u7cbe\u7ec6\u7a7a\u95f4\u5206\u8fa8\u7387\u65b9\u9762\u7684\u4f18\u52bf\uff0c\u5149\u58f0\u6210\u50cf\u6709\u671b\u7528\u4e8e\u4e34\u5e8a\u764c\u75c7\u8bca\u65ad\u3002\u4e2d\u56fd\u79d1\u5b66\u9662\u751f\u7269\u7269\u7406\u7814\u7a76\u6240\u960e\u9521\u8574\u9662\u58eb\u8bfe\u9898\u7ec4\u4e0e\u6df1\u5733\u7b2c\u4e8c\u4eba\u6c11\u533b\u9662\u8042\u56fd\u8f89\u8bfe\u9898\u7ec4\u5408\u4f5c\u63d0\u51fa\u4e86\u4e00\u79cd\u5916\u6ccc\u4f53\u6837\u3001\u5177\u6709\u8fc7\u6c27\u5316\u6c22\u54cd\u5e94\u7684\u7eb3\u7c73\u9176\u56ca\u6ce1\u7528\u4e8e\u9f3b\u54bd\u764c\u5149\u58f0\u6210\u50cf\u3002\u5177\u6709\u8fc7\u6c27\u5316\u7269\u9176\u6837\u6d3b\u6027\u7684\u77f3\u58a8\u70ef\u91cf\u5b50\u70b9\u7eb3\u7c73\u9176\uff08GQDzyme\uff09\u53ef\u5728\u8fc7\u6c27\u5316\u6c22\u5b58\u5728\u4e0b\u5c062, 2\u2019-\u8054\u6c2e\u53cc(3-\u4e59\u57fa\u82ef\u5e76\u567b\u5511\u5549-6-\u78fa\u9178)\u4e8c\u94f5\u76d0\uff08ABTS\uff09\u6709\u6548\u5730\u8f6c\u5316\u4e3a\u5176\u6c27\u5316\u5f62\u5f0f\uff08oxABTS\uff09\uff0c\u5176\u4e2doxABTS\u5177\u6709\u5f88\u5f3a\u7684\u8fd1\u7ea2\u5916\u5438\u6536\u7387\uff0c\u4f7f\u5176\u6210\u4e3a\u5149\u58f0\u6210\u50cf\u7684\u7406\u60f3\u9020\u5f71\u5242\u3002\u901a\u8fc7\u7528\u53f6\u9178\u4fee\u9970\u7684\u5929\u7136\u7ea2\u7ec6\u80de\u819c\u5bf9GQDzyme \/ ABTS\u7eb3\u7c73\u9897\u7c92\u8fdb\u884c\u4eff\u751f\u529f\u80fd\u5316\u6765\u6784\u5efa\u5916\u6ccc\u4f53\u6837\u7eb3\u7c73\u9176\u56ca\u6ce1\u7528\u4e8e\u9f3b\u54bd\u764c\u7684\u5149\u58f0\u6210\u50cf\u3002\u8be5\u5916\u6ccc\u4f53\u6837\u7eb3\u7c73\u9176\u56ca\u6ce1\u80fd\u6709\u6548\u5730\u79ef\u805a\u5728\u9f3b\u54bd\u764c\u7ec4\u7ec7\u4e2d\uff0c\u5e76\u9009\u62e9\u6027\u89e6\u53d1\u9f3b\u54bd\u764c\u7ec4\u7ec7\u4e2d\u7684\u50ac\u5316\u578b\u5149\u58f0\u6210\u50cf\u3002\u4e0e\u6b63\u5e38\u7ec4\u7ec7\u76f8\u6bd4\uff0c\u7531\u4e8e\u80bf\u7624\u7684\u5feb\u901f\u4ee3\u8c22\uff0c\u8be5\u7eb3\u7c73\u9176\u56ca\u6ce1\u80fd\u591f\u7075\u654f\u5730\u68c0\u6d4b\u9f3b\u54bd\u764c\u4e2d\u8fc7\u6c27\u5316\u6c22\u7684\u76f8\u5bf9\u589e\u52a0\uff0c\u8fd8\u5177\u6709\u4f18\u5f02\u7684\u9690\u8eab\u80fd\u529b\uff0c\u5ef6\u957f\u4e86\u5faa\u73af\u65f6\u95f4\uff0c\u5e76\u6539\u5584\u4e86\u80bf\u7624\u4e2d\u7684\u84c4\u79ef\u3002\u8fd9\u9879\u5de5\u4f5c\u662f\u57fa\u4e8e\u7eb3\u7c73\u9176\u7684\u50ac\u5316\u6210\u50cf\u7b56\u7565\u5728\u4f53\u5185\u8fdb\u884c\u7684\u9996\u6b21\u5e94\u7528\uff0c\u4e3a\u9f3b\u54bd\u764c\u7684\u6cbb\u7597\u63d0\u4f9b\u4e00\u79cd\u65b0\u7684\u601d\u8def\u3002[3]<\/sup>\u00a0\u76f8\u5173\u7814\u7a76\u4ee5\u201cExosome-like Nanozyme Vesicles for H2<\/sub>O2<\/sub>\u2011Responsive Catalytic\u00a0Photoacoustic Imaging of Xenograft Nasopharyngeal Carcinoma\u201d\u4e3a\u9898\uff0c\u53d1\u8868\u5728Nano Letters\u3002<\/p>\n

https:\/\/pubs.acs.org\/doi\/abs\/10.1021\/acs.nanolett.8b03709\u00a0<\/p>\n

\u56fe\u4e09\uff1a\u50ac\u5316\u578b\u7eb3\u7c73\u9176\u56ca\u6ce1\u7528\u4e8e\u9f3b\u54bd\u764c\u80bf\u7624\u7684\u5149\u58f0\u6210\u50cf\u7684\u793a\u610f\u56fe<\/b><\/strong><\/p>\n

\"\"<\/p>\n

\u66f2\u6653\u521a\uff08\u4e2d\u56fd\u79d1\u5b66\u9662\u957f\u6625\u5e94\u7528\u5316\u5b66\u7814\u7a76\u6240\uff09<\/b><\/strong><\/p>\n

4. ACS Nano\u7eb3\u7c73\u9176\u4f5c\u4e3a\u4f53\u5185\u4f24\u53e3\u6108\u5408\u7684\u81ea\u6fc0\u6d3b\u7ea7\u8054\u8bd5\u5242<\/strong><\/p>\n

\u7531\u4e8e\u8fc7\u6c27\u5316\u7269\u9176\u7684\u6700\u4f73\u53cd\u5e94\u53d1\u751f\u5728pH\u503c\u4e3a3-4\u7684\u5f3a\u9178\u6027\u73af\u5883\u4e2d\uff0c\u4e25\u91cd\u9650\u5236\u4e86\u5177\u6709\u8fc7\u6c27\u5316\u7269\u9176\u6837\u6d3b\u6027\u7684\u91d1\u5c5e\u6709\u673a\u6846\u67b6\uff08MOF\uff09\u5728\u751f\u7269\u533b\u5b66\u9886\u57df\u4e2d\u6027pH\u7684\u4f53\u5185\u5e94\u7528\u5f88\u5c11\uff0c\u800c\u4e14\u76f4\u63a5\u5f15\u5165\u76f8\u5bf9\u8f83\u9ad8\u6d53\u5ea6\u548c\u6bd2\u6027\u7684\u53cd\u5e94\u8bd5\u5242H2<\/sub>O2<\/sub>\u4f1a\u5bf9\u6b63\u5e38\u7ec4\u7ec7\u9020\u6210\u4e00\u5b9a\u7684\u635f\u5bb3\u3002\u4e2d\u56fd\u79d1\u5b66\u9662\u957f\u6625\u5e94\u7528\u5316\u5b66\u7814\u7a76\u6240\u66f2\u6653\u521a\u6559\u6388\u8bfe\u9898\u7ec4\u901a\u8fc7\u8d85\u8584\u4e8c\u7ef4MOF\u7eb3\u7c73\u7247\u4f5c\u4e3a\u8fc7\u6c27\u5316\u7269\u9176\u6a21\u62df\u7269\uff0c\u4ee5\u7269\u7406\u5438\u9644\u8461\u8404\u7cd6\u6c27\u5316\u9176\u6765\u5236\u5907MOF\u7eb3\u7c73\u9176\u590d\u5408\u4f53\uff0c\u5e76\u6784\u5efa\u4e86\u57fa\u4e8eMOF\u7eb3\u7c73\u9176\u590d\u5408\u4f53\u4f5c\u4e3a\u826f\u6027\u548c\u81ea\u6d3b\u5316\u7684\u7ea7\u8054\u8bd5\u5242\u7528\u4e8e\u4f53\u5185\u548c\u4f53\u5916\u6297\u83cc\u3002\u8461\u8404\u7cd6\u6c27\u5316\u9176\u53ef\u4ee5\u5c06\u65e0\u6bd2\u7684\u8461\u8404\u7cd6\u8fde\u7eed\u8f6c\u5316\u4e3a\u4e30\u5bcc\u7684\u8461\u8404\u7cd6\u9178\u548cH2<\/sub>O2<\/sub>\uff0c\u907f\u514d\u4e86\u76f4\u63a5\u4f7f\u7528\u76f8\u5bf9\u8f83\u9ad8\u6d53\u5ea6\u548c\u6709\u6bd2\u7684H2<\/sub>O2<\/sub>\uff0c\u5e76\u5c06\u6574\u4e2a\u7cfb\u7edf\u7684pH\u503c\u964d\u4f4e\u81f33-4\uff0c\u628a\u526f\u4f5c\u7528\u964d\u81f3\u6700\u4f4e\u3002\u901a\u8fc7\u50ac\u5316\u8461\u8404\u7cd6\u4ee5\u81ea\u6fc0\u6d3b2D MOF\u7eb3\u7c73\u7247\u7684\u8fc7\u6c27\u5316\u7269\u9176\u6837\u6d3b\u6027\uff0c\u540c\u65f6\u4ea7\u751f\u7684\u5927\u91cfH2<\/sub>O2<\/sub>\u53ef\u7528\u4e8e\u968f\u540e\u76842D MOF\u7eb3\u7c73\u7247\u7684\u50ac\u5316\uff0c\u4ece\u800c\u4ea7\u751f\u63d0\u9ad8\u4e86\u5267\u6bd2\u2022OH\u7684\u4ea7\u751f\u6548\u7387\u548c\u6297\u83cc\u80fd\u529b\u3002\u8fd9\u79cd\u8bbe\u8ba1\u7684\u826f\u6027\u548c\u81ea\u6fc0\u6d3b\u7ea7\u8054\u8bd5\u5242\u5177\u6709\u5f3a\u5927\u7684\u6297\u83cc\u4f5c\u7528\uff0c\u5176\u751f\u7269\u6bd2\u6027\u53ef\u5ffd\u7565\u4e0d\u8ba1\uff0c\u5e76\u4e14\u4f1a\u4fc3\u8fdb\u57fa\u4e8eMOF\u7eb3\u7c73\u9176\u5728\u751f\u7269\u5316\u5b66\u548c\u751f\u7269\u533b\u5b66\u9886\u57df\u7684\u5e94\u7528\u3002[4]<\/sup>\u00a0\u76f8\u5173\u7814\u7a76\u4ee5\u201cTwo-Dimensional Metal-Organic Framework\/Enzyme Hybrid Nanocatalyst as a Benign and\u00a0Self-Activated Cascade Reagent for in Vivo\u00a0Wound Healing\u201d\u4e3a\u9898\uff0c\u53d1\u8868\u5728ACS Nano\u3002<\/p>\n

https:\/\/pubs.acs.org\/doi\/abs\/10.1021\/acsnano.8b09501\u00a0<\/p>\n

\u56fe\u56db\uff1aMOF\u7eb3\u7c73\u9176\u590d\u5408\u4f53\u7684\u5236\u5907\u53ca\u6297\u83cc\u793a\u610f\u56fe<\/b><\/strong><\/p>\n

\"\"<\/p>\n

5. Biomaterials\u7eb3\u7c73\u9176\u7834\u574f\u751f\u7269\u819c\u5e76\u963b\u788d\u7ec6\u83cc\u7684\u589e\u6b96<\/strong><\/p>\n

\u7ec6\u83cc\u751f\u7269\u819c\u6b63\u5bf9\u5168\u7403\u516c\u5171\u5065\u5eb7\u6784\u6210\u4e25\u91cd\u5a01\u80c1\u3002\u7ec6\u80de\u5916DNA\u4f5c\u4e3a\u751f\u7269\u819c\u7ec6\u80de\u5916\u805a\u5408\u7269\u4e2d\u7684\u91cd\u8981\u6210\u5206\u53ef\u4ee5\u5c06\u4e0d\u540c\u7684\u7ec6\u80de\u5916\u805a\u5408\u7269\u6210\u5206\u548c\u7ec6\u83cc\u8fde\u63a5\u5728\u4e00\u8d77\uff0c\u5bfc\u81f4\u751f\u7269\u819c\u96be\u4ee5\u6d88\u9664\u3002\u4e2d\u56fd\u79d1\u5b66\u9662\u957f\u6625\u5e94\u7528\u5316\u5b66\u7814\u7a76\u6240\u66f2\u6653\u521a\u6559\u6388\u8bfe\u9898\u7ec4\u8bbe\u8ba1\u5e76\u5408\u6210\u4e86\u4e00\u7cfb\u5217\u5177\u6709\u548c\u8fc7\u6c27\u5316\u7269\u9176\u6a21\u62df\u6d3b\u6027\u7684MOF\/Ce\u7eb3\u7c73\u9176\u7528\u4e8e\u5bf9\u6297\u751f\u7269\u819c\u3002\u5177\u6709\u8131\u6c27\u6838\u7cd6\u6838\u9178\u9176\u6d3b\u6027\u7684\u94c8\uff08IV\uff09\u590d\u5408\u7269\u80fd\u591f\u6c34\u89e3\u7ec6\u80de\u5916DNA\u5e76\u7834\u574f\u5df2\u5efa\u7acb\u7684\u751f\u7269\u819c\uff0c\u800c\u5177\u6709\u8fc7\u6c27\u5316\u7269\u9176\u6837\u6d3b\u6027\u7684MOF\u53ef\u4ee5\u6740\u6b7b\u5b58\u5728H2<\/sub>O2<\/sub>\u65f6\u5206\u6563\u5728\u751f\u7269\u819c\u4e2d\u7684\u7ec6\u83cc\uff0c\u8fd9\u6837\u53ef\u4ee5\u907f\u514d\u7ec6\u83cc\u7684\u91cd\u65b0\u5b9a\u6b96\u548c\u751f\u7269\u819c\u7684\u590d\u53d1\u3002\u4e24\u79cd\u7eb3\u7c73\u9176\u7684\u7ed3\u5408\u662f\u83b7\u5f97\u589e\u5f3a\u7684\u6297\u751f\u7269\u819c\u6027\u80fd\u7684\u5408\u7406\u7b56\u7565\uff0c\u8fd9\u79cd\u5177\u6709\u53cc\u91cd\u9176\u6a21\u62df\u6d3b\u6027\u7684\u7eb3\u7c73\u9176\u53ef\u4ee5\u7a7f\u900f\u751f\u7269\u819c\uff0c\u5e76\u5f3a\u70c8\u6291\u5236\u7ec6\u83cc\u751f\u7269\u819c\u7684\u5f62\u6210\u3002\u8be5\u5de5\u4f5c\u6709\u52a9\u4e8e\u534f\u540c\u591a\u7eb3\u7c73\u9176\u7cfb\u7edf\u7684\u8bbe\u8ba1\uff0c\u5e76\u4e3aMOF\u7eb3\u7c73\u9176\u7684\u66f4\u6df1\u5165\u7684\u5e94\u7528\u63d0\u4f9b\u65b0\u7684\u601d\u8def\u3002[5]<\/sup>\u00a0\u76f8\u5173\u7814\u7a76\u4ee5\u201cA series of MOF\/Ce-based nanozymes with dual enzyme-like activity\u00a0disrupting biofilms and hindering recolonization of bacteria\u201d\u4e3a\u9898\uff0c\u53d1\u8868\u5728Biomaterials\u3002<\/p>\n

https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0142961219302182\u00a0<\/p>\n

\u56fe\u4e94\uff1a<\/b><\/strong>MOF\/Ce<\/b><\/strong>\u7eb3\u7c73\u9176\u7528\u4e8e\u6297\u751f\u7269\u819c\u5e94\u7528\u7684\u793a\u610f\u56fe<\/b><\/strong><\/p>\n

\"\"<\/p>\n

6. Angew. Chem. Int. Ed.\u7f3a\u9677\u4e30\u5bcc\u7684\u7eb3\u7c73\u9176\u4f5c\u4e3a\u65b0\u578b\u6297\u751f\u7d20\u589e\u5f3a\u7ec6\u83cc\u6291\u5236\u4f5c\u7528<\/strong><\/p>\n

\u7eb3\u7c73\u9176\u662f\u5177\u6709\u5e7f\u8c31\u6297\u83cc\u7279\u6027\u548c\u4f4e\u7684\u751f\u7269\u6bd2\u6027\u7684\u65b0\u4e00\u4ee3\u6297\u751f\u7d20\u3002\u4f46\u662f\u7eb3\u7c73\u9176\u4e0d\u80fd\u6355\u83b7\u7ec6\u83cc\u800c\u4e14\u50ac\u5316\u6d3b\u6027\u8f83\u4f4e\uff0c\u5bfc\u81f4\u6297\u83cc\u6548\u679c\u4e0d\u4ee4\u4eba\u6ee1\u610f\u3002\u4e2d\u56fd\u79d1\u5b66\u9662\u957f\u6625\u5e94\u7528\u5316\u5b66\u7814\u7a76\u6240\u66f2\u6653\u521a\u6559\u6388\u8bfe\u9898\u7ec4\u63d0\u51fa\u4e86\u5177\u6709\u7c97\u7cd9\u8868\u9762\u548c\u7f3a\u9677\u4e30\u5bcc\u7684\u6d3b\u6027\u8fb9\u7f18\u7684\u7eb3\u7c73\u9176\u7528\u4e8e\u6297\u83cc\u7814\u7a76\u3002\u7531\u4e8eH2<\/sub>O2<\/sub>\u8f83\u4f4e\u7684\u5438\u9644\u80fd\u548cOH*\u7684\u89e3\u5438\u80fd\u4ee5\u53ca\u6574\u4e2a\u53cd\u5e94\u7684\u8f83\u5927\u653e\u70ed\u8fc7\u7a0b\uff0c\u4e0e\u539f\u59cb\u7684\u7eb3\u7c73\u9176\u76f8\u6bd4\uff0c\u7c97\u7cd9\u7684\u8868\u9762\u589e\u52a0\u4e86\u7ec6\u83cc\u7684\u9644\u7740\u529b\uff0c\u5e76\u4e14\u5bcc\u542b\u7f3a\u9677\u7684\u8fb9\u7f18\u8868\u73b0\u51fa\u66f4\u9ad8\u7684\u8fc7\u6c27\u5316\u7269\u9176\u6837\u6d3b\u6027\u3002\u6b64\u5916\uff0c\u5f15\u5165\u5148\u5929\u6027\u5149\u70ed\u6548\u5e94\u5728\u4f53\u5916\u548c\u4f53\u5185\u5747\u5bfc\u81f4\u66f4\u9ad8\u7684\u6cbb\u7597\u6548\u679c\u3002\u8be5\u5de5\u4f5c\u4e0d\u4ec5\u5f00\u53d1\u4e86\u4e00\u79cd\u65b0\u7684\u7b56\u7565\u6765\u751f\u4ea7\u5177\u6709\u7ec6\u83cc\u6355\u83b7\u80fd\u529b\u7684\u9ad8\u6548\u7eb3\u7c73\u9176\u4f5c\u4e3a\u66ff\u4ee3\u6297\u751f\u7d20\uff0c\u800c\u4e14\u8fd8\u901a\u8fc7\u6574\u5408\u7eb3\u7c73\u62d3\u6251\u3001\u7f3a\u9677\u63ba\u5165\u548c\u50ac\u5316\u6027\u80fd\u4e3a\u751f\u7269\u6750\u6599\u8bbe\u8ba1\u63d0\u4f9b\u4e86\u65b0\u7684\u89c1\u8bc6\u3002[6]<\/sup>\u00a0\u76f8\u5173\u7814\u7a76\u4ee5\u201cDefect-Rich Adhesive Nanozymes as Efficient Antibiotics for Enhanced Bacterial Inhibition\u201d\u4e3a\u9898\uff0c\u53d1\u8868\u5728Angew. Chem. Int. Ed.\u3002<\/p>\n

https:\/\/onlinelibrary.wiley.com\/doi\/abs\/10.1002\/anie.201908289\u00a0<\/p>\n

\u56fe\u516d\uff1a\u5236\u5907\u542b\u7f3a\u9677\u7684\u7c98\u6027\u7eb3\u7c73\u9176\u548c\u7ec6\u83cc\u7684\u6355\u83b7\u548c\u6d88\u706d\u793a\u610f\u56fe<\/b><\/strong><\/p>\n

\"\"<\/p>\n

7. JACS\u7eb3\u7c73\u9176\u7684H2<\/sub>O2<\/sub>\u7a33\u6001\u7834\u574f\u5668\u7528\u4e8e\u5f3a\u5316\u5316\u5b66\u52a8\u529b\u7597\u6cd5<\/strong><\/p>\n

\u5316\u5b66\u52a8\u529b\u7597\u6cd5\uff08CDT\uff09\u662f\u901a\u8fc7\u80bf\u7624\u5185\u6e90\u6027\u523a\u6fc0\u6fc0\u6d3b\u6740\u4f24\u764c\u7ec6\u80de\u83b7\u5f97\u5e7f\u6cdb\u7684\u5173\u6ce8\u3002\u5728\u80bf\u7624\u7ec6\u80de\u4e2dCDT\u5229\u7528Fe2+<\/sup>\u4ecb\u5bfc\u7684\u82ac\u987f\u53cd\u5e94\u6216Cu2+<\/sup>\u6216Mn2+<\/sup>\u4ecb\u5bfc\u7684\u82ac\u987f\u53cd\u5e94\u53ef\u4ee5\u5c06\u53cd\u5e94\u6027\u8f83\u4f4e\u7684\u8fc7\u6c27\u5316\u6c22\u8f6c\u5316\u4e3a\u7f9f\u57fa\u81ea\u7531\u57fa\uff0c\u4ea7\u751f\u7684\u6d3b\u6027\u6c27\uff08ROS\uff09\u53ef\u4ee5\u8bf1\u5bfc\u7ec6\u80de\u51cb\u4ea1\u548c\u574f\u6b7b\uff0c\u4ece\u800c\u5b9e\u73b0\u5bf9\u80bf\u7624\u7ec6\u80de\u7684\u6740\u4f24\u3002\u4e2d\u56fd\u79d1\u5b66\u9662\u957f\u6625\u5e94\u7528\u5316\u5b66\u7814\u7a76\u6240\u66f2\u6653\u521a\u6559\u6388\u8bfe\u9898\u7ec4\u63d0\u51fa\u4e86\u4e00\u79cd\u5229\u7528\u7eb3\u7c73\u9176\u63d0\u5347\u80bf\u7624\u7ec6\u80de\u5185\u53cc\u6c27\u6c34\u542b\u91cf\u7684\u65b9\u6cd5\u3002\u7eb3\u7c73\u9176\u53ef\u4ee5\u4fc3\u8fdb\u53cc\u6c27\u6c34\u7684\u4ea7\u751f\u540c\u65f6\u80fd\u6291\u5236\u53cc\u6c27\u6c34\u5206\u89e3\uff0c\u6765\u63d0\u9ad8\u80bf\u7624\u7ec6\u80de\u5185\u7684\u53cc\u6c27\u6c34\u542b\u91cf\uff0c\u53ef\u4ee5\u7528\u4e8e\u589e\u5f3aCDT\u5bf9\u80bf\u7624\u7ec6\u80de\u7684\u6740\u4f24\u4f5c\u7528\u3002\u5b9e\u9a8c\u8bc1\u660e\u4e86\u7eb3\u7c73\u9176\u590d\u5408\u4f53\u5728\u764c\u7ec6\u80de\u5185\u53ef\u4ee5\u4fc3\u8fdb\u53cc\u6c27\u6c34\u7684\u5408\u6210\u540c\u65f6\u6291\u5236\u53cc\u6c27\u6c34\u88ab\u8c37\u80f1\u7518\u80bd\u6d88\u8017\u548c\u88ab\u8fc7\u6c27\u5316\u6c22\u9176\u7684\u5206\u89e3\uff0c\u6709\u6548\u7684\u63d0\u9ad8\u80bf\u7624\u7ec6\u80de\u5185\u53cc\u6c27\u6c34\u7684\u6c34\u5e73\uff0c\u5e76\u901a\u8fc7\u82ac\u987f\u53cd\u5e94\u5c06\u53cc\u6c27\u6c34\u8f6c\u5316\u6210\u5bf9\u80bf\u7624\u7ec6\u80de\u6709\u6740\u4f24\u80fd\u529b\u7684\u7f9f\u57fa\u81ea\u7531\u57fa\u3002\u8be5\u65b9\u6cd5\u7684\u5f00\u53d1\u4e3a\u5176\u5b83\u6fc0\u6d3b\u65b9\u5f0f\u63d0\u9ad8CDT\u6cbb\u7597\u80fd\u529b\u63d0\u4f9b\u4e86\u4e00\u4e2a\u65b0\u7684\u601d\u8def\u3002[7] <\/sup>\u76f8\u5173\u7814\u7a76\u4ee5\u201cBioinspired Construction of a Nanozyme-Based H2<\/sub>O2<\/sub>\u00a0Homeostasis Disruptor for Intensive Chemodynamic Therapy\u201d\u4e3a\u9898\uff0c\u53d1\u8868\u5728J. Am. Chem. Soc.\u3002<\/p>\n

https:\/\/pubs.acs.org\/doi\/abs\/10.1021\/jacs.9b12873\u00a0<\/p>\n

\u56fe\u4e03\uff1a\u7eb3\u7c73\u9176\u590d\u5408\u4f53\u5408\u6210\u53ca\u5316\u5b66\u52a8\u529b\u7597\u6cd5\u793a\u610f\u56fe<\/b><\/strong><\/p>\n

\"\"<\/b><\/strong><\/p>\n

8. Adv. Funct. Mater.\u7eb3\u7c73\u9176\u6c34\u51dd\u80f6\u589e\u5f3a\u6355\u83b7\u548c\u6d88\u706d\u7ec6\u83cc\u7684\u80fd\u529b<\/strong><\/p>\n

\u6ee5\u7528\u6297\u751f\u7d20\u5f15\u8d77\u7684\u5e7f\u6cdb\u7684\u591a\u836f\u8010\u836f\u6027\u4fc3\u4f7f\u7814\u7a76\u4eba\u5458\u63a2\u7d22\u6cbb\u7597\u7ec6\u83cc\u611f\u67d3\u7684\u65b0\u65b9\u6cd5\u3002\u7eb3\u7c73\u9176\u53ef\u4ee5\u6a21\u62df\u5929\u7136\u9176\u7684\u529f\u80fd\uff0c\u4ee5\u8bf1\u5bfc\u4ea7\u751f\u9ad8\u6bd2\u6027\u7684\u6d3b\u6027\u6c27\uff08ROS\uff09\u4f5c\u4e3a\u6297\u83cc\u5242\u3002\u4f46\u662f\uff0c\u7eb3\u7c73\u9176\u548c\u7ec6\u83cc\u4e4b\u95f4\u7f3a\u4e4f\u6709\u6548\u7684\u76f8\u4e92\u4f5c\u7528\uff0c\u5e76\u4e14\u5185\u5728\u6d3b\u6027\u6c27\u7684\u56fa\u6709\u5bff\u547d\u77ed\u548c\u6269\u6563\u8ddd\u79bb\u6781\u5927\u5730\u51cf\u5f31\u4e86\u5b83\u4eec\u7684\u6740\u83cc\u6d3b\u6027\u3002\u4e2d\u56fd\u79d1\u5b66\u9662\u957f\u6625\u5e94\u7528\u5316\u5b66\u7814\u7a76\u6240\u66f2\u6653\u521a\u6559\u6388\u8bfe\u9898\u7ec4\u5f00\u53d1\u4e86\u5e26\u6b63\u7535\u8377\u4e14\u591a\u5b54\u7684MoS2<\/sub>\u7eb3\u7c73\u9176-\u6c34\u51dd\u80f6\u4ee5\u5b9e\u73b0\u589e\u5f3a\u7684\u6297\u83cc\u5242\u3002\u5177\u6709\u6b63\u7535\u8377\u548c\u5927\u5b54\u7279\u6027\u7684\u7eb3\u7c73\u9176-\u6c34\u51dd\u80f6\u53ef\u4ee5\u6355\u83b7\u548c\u9650\u5236ROS\u7834\u574f\u8303\u56f4\u5185\u7684\u7ec6\u83cc\u3002\u901a\u8fc7\u7ed3\u5408MoS2<\/sub>\u7eb3\u7c73\u9176\u7684\u8fd1\u7ea2\u5916\u5149\u70ed\u6027\u8d28\uff0c\u7eb3\u7c73\u9176-\u6c34\u51dd\u80f6\u53ef\u4ee5\u5b9e\u73b0\u534f\u540c\u7684\u6740\u83cc\u4f5c\u7528\uff0c\u5e76\u6d88\u9664\u7ec6\u83cc\u5e76\u964d\u4f4e\u53d1\u708e\u7684\u98ce\u9669\uff0c\u76ae\u80a4\u4f24\u53e3\u7684\u6108\u5408\u901f\u5ea6\u5c06\u52a0\u5feb\u3002\u901a\u8fc7MoS2<\/sub>\u7eb3\u7c73\u9176-\u6c34\u51dd\u80f6\u4f18\u826f\u7279\u6027\u63d0\u9ad8\u7eb3\u7c73\u9176\u6297\u83cc\u6027\u80fd\uff0c\u540c\u65f6\u4fc3\u8fdb\u4f24\u53e3\u6108\u5408\u7684\u539f\u59cb\u7b56\u7565\u3002\u7eb3\u7c73\u9176\u548c\u6c34\u51dd\u80f6\u7684\u7ed3\u5408\u51cf\u5c11\u4e86MoS2<\/sub>\u7eb3\u7c73\u9176\u5bf9\u7ec4\u7ec7\u7684\u635f\u4f24\uff0c\u4e3a\u6709\u6548\u6d88\u9664\u7ec6\u83cc\u548c\u66f4\u597d\u7684\u751f\u7269\u5b89\u5168\u6027\u63d0\u4f9b\u4e86\u66f4\u597d\u7684\u9009\u62e9\uff0c\u5e76\u4e14\u53ef\u4ee5\u4e3a\u7eb3\u7c73\u9176\u7684\u5e7f\u6cdb\u6297\u83cc\u7814\u7a76\u63d0\u4f9b\u65b0\u89c1\u89e3\u3002[8]<\/sup>\u00a0\u76f8\u5173\u7814\u7a76\u4ee5\u201cConstruction of Nanozyme-Hydrogel for Enhanced Capture\u00a0and Elimination of Bacteria\u201d\u4e3a\u9898\uff0c\u53d1\u8868\u5728Adv. Funct. Mater.\u3002<\/p>\n

https:\/\/onlinelibrary.wiley.com\/doi\/abs\/10.1002\/adfm.201900518<\/p>\n

\u56fe\u516b\uff1a\u5236\u5907MoS<\/b><\/strong>2<\/b><\/sub><\/strong>\u7eb3\u7c73\u9176-\u6c34\u51dd\u80f6\u53ca\u5176\u7528\u4e8e\u6e05\u9664\u7ec6\u83cc\u548c\u4f24\u53e3\u611f\u67d3\u7684\u6cbb\u7597\u793a\u610f\u56fe<\/b><\/strong><\/p>\n

\"\"<\/p>\n

\u9b4f\u8f89<\/b><\/strong>\uff08<\/b><\/strong>\u5357\u4eac\u5927\u5b66<\/b><\/strong>\uff09<\/b><\/strong><\/p>\n

9. Small\u7eb3\u7c73\u9176\u7528\u4e8e\u6e05\u9664\u9999\u70df\u70df\u96fe\u4e2d\u7684ROS<\/strong><\/p>\n

\u5168\u7403\u70df\u8349\u4ecd\u7136\u662f\u5bf9\u516c\u5171\u536b\u751f\u7684\u6bc1\u706d\u6027\u5a01\u80c1\u3002\u9999\u70df\u70df\u96fe\u4e2d\u7684\u6709\u6bd2\u6d3b\u6027\u6c27\uff08ROS\uff09\u65e0\u6cd5\u901a\u8fc7\u5f53\u524d\u53ef\u7528\u7684\u9999\u70df\u8fc7\u6ee4\u5634\u6709\u6548\u5730\u6d88\u9664\uff0c\u4ea7\u751f\u7684\u6c27\u5316\u5e94\u6fc0\u4f1a\u5bfc\u81f4\u4e25\u91cd\u7684\u80ba\u635f\u4f24\u548c\u5176\u4ed6\u75be\u75c5\u3002\u5357\u4eac\u5927\u5b66\u9b4f\u8f89\u6559\u6388\u8bfe\u9898\u7ec4\u63d0\u51fa\u4e86\u4f7f\u7528\u65b0\u578b\u94dc\u97a3\u9178\u914d\u4f4d\uff08CuTA\uff09\u7eb3\u7c73\u9176\u4f5c\u4e3a\u9ad8\u6d3b\u6027\u548c\u70ed\u7a33\u5b9a\u7684ROS\u6e05\u9664\u5242\u3002CuTA\u7eb3\u7c73\u9176\u8868\u73b0\u51fa\u8d85\u6c27\u5316\u7269\u6b67\u5316\u9176\u6837\u6d3b\u6027\uff0c\u8fc7\u6c27\u5316\u6c22\u9176\u6837\u6d3b\u6027\u548c\u7f9f\u57fa\u81ea\u7531\u57fa\u6d88\u9664\u80fd\u529b\u3002\u8fd9\u4e9b\u534f\u540c\u7684\u6297\u6c27\u5316\u80fd\u529b\u4f7fCuTA\u7eb3\u7c73\u9176\u6210\u4e3a\u6539\u5584\u5546\u7528\u9999\u70df\u8fc7\u6ee4\u5634\u6709\u6f5c\u529b\u7684\u5e94\u7528\u9886\u57df\u3002\u8f7d\u6709CuTA\u7eb3\u7c73\u9176\u7684\u5546\u7528\u5377\u70df\u53ef\u6709\u6548\u6e05\u9664\u5377\u70df\u70df\u6c14\u4e2d\u7684ROS\uff0c\u51cf\u5c11\u6c27\u5316\u5e94\u6fc0\u5f15\u8d77\u7684\u80ba\u90e8\u708e\u75c7\uff0c\u5e76\u6700\u5927\u7a0b\u5ea6\u51cf\u5c11\u6025\u6027\u80ba\u635f\u4f24\u3002CuTA\u7eb3\u7c73\u9176\u63d0\u4f9b\u4e86\u5177\u6709\u591a\u79cd\u6297\u6c27\u5316\u80fd\u529b\u7684\u6709\u6548ROS\u6e05\u9664\u5242\uff0c\u4e3a\u4fee\u9970\u9999\u70df\u8fc7\u6ee4\u5634\u4ee5\u51cf\u5c11\u9999\u70df\u70df\u96fe\u7684\u6bd2\u6027\u5f00\u521b\u4e86\u65b0\u7684\u673a\u9047\u3002[9]<\/sup>\u00a0\u76f8\u5173\u7814\u7a76\u4ee5\u201cCopper Tannic Acid Coordination Nanosheet: A Potent\u00a0Nanozyme for Scavenging ROS from Cigarette Smoke\u201d\u4e3a\u9898\uff0c\u53d1\u8868\u5728Small.<\/p>\n

https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1002\/smll.201902123<\/p>\n

\u56fe\u4e5d\uff1aCuTA\u7eb3\u7c73\u9176\u5e94\u7528\u4e8e\u9999\u70df\u8fc7\u6ee4\u5634ROS\u6e05\u9664\u7684\u8bbe\u8ba1\u548c\u5408\u6210\u793a\u610f\u56fe<\/b><\/strong><\/p>\n

\"\"<\/p>\n

10. Anal. Chem.\u7eb3\u7c73\u9176\u7528\u4e8e\u603b\u6297\u6c27\u5316\u80fd\u529b\u7684\u6d4b\u5b9a<\/strong><\/p>\n

\u7531\u4e8e\u5728\u6c2e\u63ba\u6742\u7684\u78b3\u7eb3\u7c73\u9176\u4e2d\u7684\u91cd\u6784\u7535\u5b50\u7ed3\u6784\u5bf9\u4e8e\u50ac\u5316\u8fc7\u7a0b\u662f\u6709\u5229\u7684\uff0c\u56e0\u6b64\u6c2e\u63ba\u6742\u7b56\u7565\u4ee5\u589e\u5f3a\u78b3\u7eb3\u7c73\u9176\u7684\u6d3b\u6027\u3002\u7136\u800c\uff0c\u7531\u4e8e\u6c2e\u5143\u7d20\u5728\u9ad8\u7145\u70e7\u6e29\u5ea6\u4e0b\u7684\u4e0d\u7a33\u5b9a\u6027\uff0c\u4ecd\u7136\u96be\u4ee5\u83b7\u5f97\u5177\u6709\u9ad8\u6c2e\u542b\u91cf\u7684\u78b3\u7eb3\u7c73\u9176\u3002\u5357\u4eac\u5927\u5b66\u9b4f\u8f89\u6559\u6388\u8bfe\u9898\u7ec4\u63d0\u51fa\u4e86\u4e00\u79cd\u65b0\u7684\u6c2e\u63ba\u6742\u7b56\u7565\uff0c\u4ee5\u9ad8\u542b\u6c2e\u805a\u5408\u7269\uff08\u805a\u4e59\u70ef\u4e9a\u80fa\uff08PEI\uff09\uff09\u4e3a\u6c2e\u6e90\u548c\u5929\u7136\u7c98\u571f\u77ff\u7269\uff08\u8499\u8131\u571f\uff08MMT\uff09\uff09\u4f5c\u4e3a\u6a21\u677f\uff0c\u4ee5\u5236\u5907\u9ad8\u6d3b\u6027\u7684\u8fc7\u6c27\u5316\u7269\u9176\u6837\u78b3\u7eb3\u7c73\u9176\u3002\u5e26\u6709PEI\u7684MMT\u7684\u7ec4\u88c5\u53ef\u5728\u9ad8\u7145\u70e7\u6e29\u5ea6\u4e0b\u4fdd\u62a4\u6c2e\u5143\u7d20\u7684\u635f\u5931\uff0c\u4ece\u800c\u4fdd\u7559\u66f4\u591a\u7684\u50ac\u5316\u6d3b\u6027\u6c2e\u4f4d\u70b9\u3002\u7f9f\u57fa\u81ea\u7531\u57fa\u662f\u8fc7\u6c27\u5316\u7269\u9176\u6837\u50ac\u5316\u4f5c\u7528\u7684\u5173\u952e\u4e2d\u95f4\u4f53\uff0c\u901a\u8fc7\u4f7f\u7528\u5177\u6709\u9ad8\u6d3b\u6027\u548c\u7279\u5b9a\u7684\u78b3\u7eb3\u7c73\u9176\u6765\u68c0\u6d4bH2<\/sub>O2<\/sub>\u3001\u8461\u8404\u7cd6\u548c\u6297\u574f\u8840\u9178\uff0c\u5e76\u68c0\u6d4b\u4e86\u56db\u79cd\u5546\u4e1a\u996e\u6599\u4e2d\u7684\u603b\u6297\u6c27\u5316\u80fd\u529b\u3002\u8be5\u7814\u7a76\u4e0d\u4ec5\u63d0\u4f9b\u4e86\u4e00\u79cd\u5236\u5907\u8fc7\u6c27\u5316\u7269\u9176\u6837\u7eb3\u7c73\u9176\u7684\u65b0\u7b56\u7565\uff0c\u800c\u4e14\u8fd8\u5f00\u53d1\u4e86\u4e00\u79cd\u7b80\u4fbf\u7684\u603b\u6297\u6c27\u5316\u80fd\u529b\u6d4b\u5b9a\u6cd5\uff0c\u53ef\u7528\u4e8e\u5c06\u6765\u8bc4\u4f30\u533b\u7597\u4fdd\u5065\u4e2d\u7684\u6297\u6c27\u5316\u5242\u98df\u54c1\u8d28\u91cf\u548c\u6c27\u5316\u5e94\u6fc0\u3002[10]<\/sup>\u00a0\u76f8\u5173\u7814\u7a76\u4ee5\u201cN\u2011Doped Carbon As Peroxidase-Like Nanozymes for Total\u00a0Antioxidant Capacity Assay\u201d\u4e3a\u9898\uff0c\u53d1\u8868\u5728Anal. Chem.\u3002<\/p>\n

https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.analchem.9b04333<\/p>\n

\u56fe\u5341\uff1a\u78b3\u7eb3\u7c73\u9176\u7684\u5236\u5907\u53ca\u5176\u603b\u6297\u6c27\u5316\u80fd\u529b\u6d4b\u5b9a<\/b><\/strong><\/p>\n

\"\"<\/p>\n

11. Anal. Chem.\u8367\u5149\u7eb3\u7c73\u9176\u6bd4\u7387\u751f\u7269\u4f20\u611f<\/strong><\/p>\n

\u5f53\u524d\u5927\u591a\u6570\u7eb3\u7c73\u9176\u751f\u7269\u4f20\u611f\u7cfb\u7edf\u5747\u57fa\u4e8e\u5355\u4fe1\u53f7\u8f93\u51fa\uff0c\u8fd9\u79cd\u68c0\u6d4b\u7cfb\u7edf\u5f88\u5bb9\u6613\u53d7\u5230\u73af\u5883\u548c\u4e2a\u4eba\u56e0\u7d20\u7684\u5f71\u54cd\uff0c\u4f46\u662f\u5177\u6709\u6bd4\u4f8b\u4fe1\u53f7\u8f93\u51fa\u7684\u7eb3\u7c73\u9176\u4f20\u611f\u7cfb\u7edf\u5c06\u63d0\u4f9b\u66f4\u53ef\u9760\uff0c\u66f4\u5f3a\u5927\u7684\u4f20\u611f\u6027\u80fd\u3002\u5357\u4eac\u5927\u5b66\u9b4f\u8f89\u6559\u6388\u8bfe\u9898\u7ec4\u5236\u5907\u4e86\u4e09\u79cd\u5177\u6709\u8fc7\u6c27\u5316\u7269\u9176\u6837\u6d3b\u6027\u7684g-C3<\/sub>N4<\/sub>\u7684\u8367\u5149\u7eb3\u7c73\u9176\uff0c\u5e76\u57fa\u4e8eg-C3<\/sub>N4<\/sub>-Ru\u7eb3\u7c73\u9176\u6784\u5efa\u4e86\u4e00\u79cd\u7528\u4e8e\u8fc7\u6c27\u5316\u6c22\u53ca\u5176\u76f8\u5173\u4ee3\u8c22\u4ea7\u7269\u7684\u6bd4\u4f8b\u8367\u5149\u4f20\u611f\u5668\u3002\u8367\u5149\u7eb3\u7c73\u9176\u5728385 nm\u6fc0\u53d1\u65f6\u53d1\u51fa438 nm\u7684\u8367\u5149\uff0c\u5728H2<\/sub>O2<\/sub>\u548c\u7eb3\u7c73\u9176\u7684\u5b58\u5728\u4e0b\u90bb\u82ef\u4e8c\u80fa\u88ab\u50ac\u5316\u6c27\u5316\u4e3aoxOPD\uff0c\u5176\u4e2doxOPD\u4e0d\u4ec5\u53ef\u4ee5\u53d1\u51fa564 nm\u5904\u7684\u8367\u5149\uff0c\u8fd8\u53ef\u4ee5\u731d\u706d\u8be5\u7eb3\u7c73\u9176\u4e0a438 nm\u5904\u7684\u8367\u5149\u3002\u5229\u7528\u5728564 nm\u548c438 nm\u5904\u7684\u8367\u5149\u5f3a\u5ea6\u4e4b\u6bd4\u4f5c\u4e3a\u4fe1\u53f7\u8f93\u51fa\uff0c\u4ee5\u6784\u5efa\u6bd4\u4f8b\u5f0f\u751f\u7269\u4f20\u611f\u7cfb\u7edf\u7528\u4e8e\u68c0\u6d4b\u78f7\u9178\u76d0\u548c\u8fc7\u6c27\u5316\u6c22\u53ca\u5176\u76f8\u5173\u4ee3\u8c22\u4ea7\u7269\u3002\u8fd9\u9879\u7814\u7a76\u63d0\u51fa\u4e86\u4e00\u79cd\u6784\u5efa\u6bd4\u4f8b\u7eb3\u7c73\u9176\u751f\u7269\u4f20\u611f\u7cfb\u7edf\u7684\u65b0\u65b9\u6cd5\u3002[11]<\/sup>\u00a0\u76f8\u5173\u7814\u7a76\u4ee5\u201cFluorescent Graphitic Carbon Nitride-Based Nanozymes with Peroxidase-Like Activities for Ratiometric Biosensing\u201d\u4e3a\u9898\uff0c\u53d1\u8868\u5728Anal. Chem.\u3002<\/p>\n

https:\/\/pubs.acs.org\/doi\/abs\/10.1021\/acs.analchem.9b01884\u00a0<\/p>\n

\u56fe\u5341\u4e00\uff1ag-C<\/b><\/strong>3<\/b><\/sub><\/strong>N<\/b><\/strong>4<\/b><\/sub><\/strong>\u8367\u5149\u7eb3\u7c73\u9176\u6bd4\u4f8b\u751f\u7269\u4f20\u611f\u793a\u610f\u56fe<\/b><\/strong><\/p>\n

\"\"<\/p>\n

12. Nature Communications eg<\/sub>\u5360\u6709\u7387\u4f5c\u4e3a\u9499\u949b\u77ff\u7eb3\u7c73\u9176\u50ac\u5316\u6d3b\u6027\u7684\u6709\u6548\u8bc4\u4f30<\/strong><\/p>\n

\u8fc7\u6c27\u5316\u7269\u9176\u7528\u4e8e\u50ac\u5316\u8fc7\u6c27\u5316\u7269\u5e95\u7269\u7684\u6c27\u5316\u3002\u4f46\u662f\u7f3a\u4e4f\u9884\u6d4b\u6027\u7684\u63cf\u8ff0\uff0c\u8fc7\u6c27\u5316\u7269\u9176\u7c7b\u548c\u5176\u4ed6\u9176\u7c7b\u7eb3\u7c73\u6750\u6599\uff08\u79f0\u4e3a\u7eb3\u7c73\u9176\uff09\u7684\u63a2\u7d22\u4e3b\u8981\u4f9d\u9760\u53cd\u590d\u8bd5\u9a8c\u7684\u7b56\u7565\u3002\u5357\u4eac\u5927\u5b66\u9b4f\u8f89\u6559\u6388\u8bfe\u9898\u7ec4\u7814\u7a76\u4e86eg<\/sub>\u8f68\u9053\u7684\u5360\u6709\u7387\u4f5c\u4e3a\u8fc7\u6e21\u91d1\u5c5e\u6c27\u5316\u7269\uff08\u5305\u62ec\u9499\u949b\u77ff\u6c27\u5316\u7269\uff09\u7eb3\u7c73\u9176\u8fc7\u6c27\u5316\u7269\u9176\u6837\u6d3b\u6027\u7684\u8bc4\u4f30\u6307\u6807\u3002\u7531\u4e8e\u6c27\u5728\u8fd9\u4e9b\u4eff\u751f\u50ac\u5316\u53cd\u5e94\u4e2d\u8d77\u7740\u6838\u5fc3\u4f5c\u7528\uff0ceg<\/sub>\u8f68\u9053\u5360\u6709\u7387\u53ef\u80fd\u63a7\u5236\u9499\u949b\u77ff\u578b\u8fc7\u6e21\u91d1\u5c5e\u6c27\u5316\u7269\u7684\u8fc7\u6c27\u5316\u7269\u9176\u6837\u6d3b\u6027\u3002\u5229\u7528\u5177\u6709BO6<\/sub>\u516b\u9762\u4f53\u4e9a\u57fa\u7684ABO3<\/sub>\u578b\u9499\u949b\u77ff\u578b\u8fc7\u6e21\u91d1\u5c5e\u6c27\u5316\u7269\u4f5c\u4e3a\u6a21\u578b\u7cfb\u7edf\u7814\u7a76\u5176\u50ac\u5316\u6d3b\u6027\u4e0eeg<\/sub>\u8f68\u9053\u5360\u6709\u7387\u7684\u5173\u7cfb\uff0c\u901a\u8fc7\u8c03\u8282ABO3<\/sub>\u7ec4\u6210\u6765\u4fc3\u8fdbeg<\/sub>\u8f68\u9053\u5360\u6709\u7387\u8c03\u8282\u3002\u5b9e\u9a8c\u6d4b\u8bd5\u548c\u5bc6\u5ea6\u6cdb\u51fd\u7406\u8bba\u8ba1\u7b97\u5747\u63ed\u793a\u4e86eg<\/sub>\u8f68\u9053\u7684\u5360\u6709\u7387\u4e0e\u7eb3\u7c73\u9176\u6d3b\u6027\u4e4b\u95f4\u7684\u706b\u5c71\u5173\u7cfb\uff0c\u5176\u4e2d\u8fc7\u6c27\u5316\u7269\u9176\u6837\u6d3b\u6027\u6700\u9ad8\uff0c\u5bf9\u5e94\u4e8eeg<\/sub>\u8f68\u9053\u7ea61.2\u7684\u5360\u6709\u7387\u3002\u8be5\u7814\u7a76\u63d0\u4f9b\u4e86\u5bf9\u7eb3\u7c73\u9176\u8fc7\u6c27\u5316\u7269\u9176\u6837\u6d3b\u6027\u50ac\u5316\u673a\u5236\u7684\u6df1\u5165\u4e86\u89e3\u4ee5\u53ca\u7eb3\u7c73\u9176\u7684\u9002\u5e94\u6027\u7ed3\u6784\u548c\u50ac\u5316\u6d3b\u6027\u7684\u5173\u7cfb\uff0c\u7ed9\u8fdb\u4e00\u6b65\u63a2\u7d22eg<\/sub>\u8f68\u9053\u7684\u5360\u6709\u7387\u6765\u9884\u6d4b\u5176\u4ed6\u91d1\u5c5e\u6c27\u5316\u7269\u7684\u9176\u6837\u6d3b\u6027\u63d0\u4f9b\u4e86\u65b0\u7684\u89c1\u89e3\u3002[12] <\/sup>\u76f8\u5173\u7814\u7a76\u4ee5\u201ceg<\/sub>\u00a0occupancy as an effective descriptor for the\u00a0catalytic activity of perovskite oxide-based\u00a0peroxidase mimics\u201d\u4e3a\u9898\uff0c\u53d1\u8868\u5728Nature Communications\u3002<\/p>\n

https:\/\/www.nature.com\/articles\/s41467-019-08657-5<\/p>\n

\u56fe\u5341\u4e8c\uff1a\u9499\u949b\u77ff\u578b\u8fc7\u6e21\u91d1\u5c5e\u6c27\u5316\u7269\u8fc7\u6c27\u5316\u7269\u9176\u6d3b\u6027\u7814\u7a76\u793a\u610f\u56fe<\/b><\/strong><\/p>\n

\"\"<\/p>\n

\u53c2\u8003\u6587\u732e<\/strong><\/p>\n

1. Zhao S., Duan H., Yang Y., et al. Fenozyme Protects the Integrity of the Blood-Brain Barrier againstExperimental Cerebral Malaria. [J] Nano Lett. 2019, 19, 8887-8895.<\/p>\n

2. Xu B., Wang H., Wang W., et al. Single-Atom Nanozyme for Wound Antibacterial Applications. [J] Angew. Chem. Int. Ed.2019, 58, 4911-4916.<\/p>\n

3. Ding H., Cai Y, GaoL., et al.Exosome-like Nanozyme Vesicles for H2<\/sub>O2<\/sub>\u2011Responsive Catalytic\u00a0Photoacoustic Imaging of Xenograft Nasopharyngeal Carcinoma. [J] Nano Lett. 2019, 19, 203-209.<\/p>\n

4. Liu X., Yan Z., Zhang Y., et al. Two-Dimensional Metal-Organic Framework\/Enzyme Hybrid Nanocatalyst as a Benign andSelf-Activated Cascade Reagent for in VivoWound Healing. [J] ACS Nano 2019, 13, 5222-5230.<\/p>\n

5. LiuZ., WangF., Ren J., et al. A series of MOF\/Ce-based nanozymes with dual enzyme-like activity\u00a0disrupting biofilms and hindering recolonization of bacteria. [J] Biomaterials 2019, 208,\u00a021-31.\u00a0<\/p>\n

6. Cao F., Zhang L., Wang H., et al. Defect-Rich Adhesive Nanozymes as Efficient Antibiotics forEnhanced Bacterial Inhibition. [J]Angew. Chem. Int. Ed. 2019, 58, 16236-16242.<\/p>\n

7. SangY.,Cao\u00a0F.,\u00a0Li\u00a0W., et al.\u00a0Bioinspired Construction of a Nanozyme-Based H2<\/sub>O2<\/sub> Homeostasis Disruptor for Intensive Chemodynamic Therapy. [J] J. Am. Chem. Soc.\u00a0DOI: 10.1021\/jacs.9b12873.<\/p>\n

8. Sang Y., Li W., Liu H.,et al. Construction of Nanozyme-Hydrogel for Enhanced Captureand Elimination of Bacteria. [J] Adv. Funct. Mater. 2019, 29, 1900518.<\/p>\n

9. Lin S., Cheng Y., Zhang H., et al.Copper Tannic Acid Coordination Nanosheet: A PotentNanozyme for Scavenging ROS from Cigarette Smoke. [J] Small 2019, 1902123.<\/p>\n

10. Lou Z., Zhao S., Wang Q.,et al. N\u2011Doped Carbon As Peroxidase-Like Nanozymes for TotalAntioxidant Capacity Assay. [J] Anal. Chem. 2019, 91, 15267-15274.<\/p>\n

11. Wang X., Qin L., Lin M., et al. Fluorescent Graphitic Carbon Nitride-Based Nanozymeswith Peroxidase-like Activities for Ratiometric Biosensing. [J] Anal. Chem. 2019, 91, 10648-10656.<\/p>\n

12. Wang X., Gao X., Qin L., et al.eg<\/sub>occupancy as an effective descriptor for the catalytic activity of perovskite oxide-based peroxidase mimics. [J] Nature Communications 2019, 10, 704.<\/p>\n

\u672c\u6587\u7531\u559c\u6b22\u957f\u9888\u9e7f\u7684\u9ad8<\/strong>\u4f9b\u7a3f\u3002<\/p>\n

\u6b22\u8fce\u5927\u5bb6\u5230\u6750\u6599\u4eba\u5ba3\u4f20\u79d1\u6280\u6210\u679c\u5e76\u5bf9\u6587\u732e\u8fdb\u884c\u6df1\u5165\u89e3\u8bfb\uff0c\u6295\u7a3f\u90ae\u7bb1: tougao@cailiaoren.com.<\/p>\n

\u6295\u7a3f\u4ee5\u53ca\u5185\u5bb9\u5408\u4f5c\u53ef\u52a0\u7f16\u8f91\u5fae\u4fe1\uff1acailiaorenVIP\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"

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