{"id":190641,"date":"2019-11-22T08:30:48","date_gmt":"2019-11-22T00:30:48","guid":{"rendered":"\/\/m.iemloyee.com\/?p=190641"},"modified":"2019-11-22T08:24:28","modified_gmt":"2019-11-22T00:24:28","slug":"%e5%8d%97%e5%bc%80%e5%a4%a7%e5%ad%a6%e6%9c%80%e6%96%b0science%e6%8a%a5%e9%81%93%ef%bc%9a%e5%88%a9%e7%94%a8%e4%b8%b2%e8%81%94%e5%82%ac%e5%8c%96%e5%89%82%e9%ab%98%e5%ba%a6%e5%af%b9%e6%98%a0%e9%80%89","status":"publish","type":"post","link":"\/\/m.iemloyee.com\/?p=190641","title":{"rendered":"\u5357\u5f00\u5927\u5b66\u6700\u65b0Science\u62a5\u9053\uff1a\u5229\u7528\u4e32\u8054\u50ac\u5316\u5242\u9ad8\u5ea6\u5bf9\u6620\u9009\u62e9\u6027\u7684\u5c06\u5361\u5bbe\u5d4c\u5165\u8102\u80aa\u80fa\u7684N-H\u952e\u4e2d"},"content":{"rendered":"<p><strong>\u3010\u80cc\u666f\u4ecb\u7ecd\u3011<\/strong><\/p>\n<p>\u5982\u4eca\uff0c\u5728\u5929\u7136\u4ea7\u7269\u3001\u5408\u6210\u836f\u7269\u548c\u519c\u836f\u4e2d\u65e0\u5904\u4e0d\u5b58\u5728\u5177\u6709\u624b\u6027\u7684\u80fa\u7ed3\u6784\u3002\u636e\u7edf\u8ba1\uff0c\u57282016\u5e74\u6392\u540d\u524d200\u4f4d\u7684\u5904\u65b9\u836f\u4e2d\u7ea6\u670943\uff05\u5305\u542b\u8102\u80aa\u80fa\u90e8\u5206\u3002\u56e0\u6b64\uff0c\u6784\u5efaC-N\u952e\u7684\u9ad8\u5bf9\u6620\u9009\u62e9\u6027\u8fc7\u6e21\u91d1\u5c5e\u50ac\u5316\u53cd\u5e94\u7684\u53d1\u5c55\u4e00\u76f4\u88ab\u5e7f\u6cdb\u7684\u5173\u6ce8\u548c\u7814\u7a76\u3002\u5176\u4e2d\uff0c\u8fc7\u6e21\u91d1\u5c5e\u50ac\u5316\u7684\u7c7b\u80e1\u841d\u535c\u7d20\u63d2\u5165N-H\u952e\u88ab\u8bc1\u660e\u662f\u4e00\u79cd\u7b80\u5355\u7684\u65b9\u6cd5\uff0c\u5177\u6709\u6e29\u548c\u7684\u53cd\u5e94\u6761\u4ef6\u3001\u826f\u597d\u7684\u5b98\u80fd\u56e2\u8010\u53d7\u6027\u548c\u53cd\u5e94\u7269\u6613\u5f97\u7b49\u4f18\u52bf\u3002\u6700\u8fd1\uff0c\u624b\u6027\u8fc7\u6e21\u91d1\u5c5e\u50ac\u5316\u5242\u5df2\u6210\u529f\u5730\u7528\u4e8e\u5929\u7136\u6216\u975e\u5929\u7136\u624b\u6027\u03b1-\u6c28\u57fa\u9178\u884d\u751f\u7269\u5408\u6210\u4e2d\u7684\u5bf9\u6620\u9009\u62e9\u6027N-H\u63d2\u5165\u53cd\u5e94\uff0c\u4f46\u662f\u8fd9\u4e9b\u53cd\u5e94\u4ec5\u9650\u4e8e\u82b3\u9999\u80fa\u6216\u9170\u80fa\u3002\u7136\u800c\uff0c\u7531\u4e8e\u8102\u80aa\u80fa\u5177\u6709\u5f88\u5f3a\u5730\u914d\u4f4d\u4f5c\u7528\uff0c\u56e0\u6b64\u8f83\u5bb9\u6613\u6291\u5236\u8fc7\u6e21\u91d1\u5c5e\u50ac\u5316\u5242\u7684\u6d3b\u6027\uff0c\u4ece\u800c\u5bf9\u6c2e-\u6c22\uff08N-H\uff09\u952e\u63d2\u5165\u53cd\u5e94\u63d0\u51fa\u4e86\u663e\u7740\u7684\u6311\u6218\u3002<\/p>\n<p><strong>\u3010\u6210\u679c\u7b80\u4ecb\u3011<\/strong><\/p>\n<p>\u4eca\u65e5\uff0c<strong>\u5357\u5f00\u5927\u5b66\u7684\u5468\u5176\u6797\u6559\u6388\u548c\u6731\u5b88\u975e\u6559\u6388\uff08\u5171\u540c\u901a\u8baf\u4f5c\u8005\uff09<\/strong>\u8054\u5408\u62a5\u9053\u4e86\u4ed6\u4eec\u5229\u7528\u4e24\u79cd\u50ac\u5316\u5242\uff08\u975e\u624b\u6027\u94dc\u914d\u5408\u7269\u548c\u624b\u6027\u6c28\u57fa-\u786b\u8132\uff09\u4e32\u8054\u50ac\u5316\uff0c\u9ad8\u5ea6\u5bf9\u6620\u9009\u62e9\u6027\u7684\u5c06\u5361\u5bbe\u63d2\u5165\u8102\u80aa\u80fa\u7684N-H\u952e\u4e2d\u3002\u5176\u4e2d\uff0c\u5229\u7528\u9ad8\u76d0\u914d\u4f53\u914d\u4f4d\u4fdd\u62a4\u6fc0\u6d3b\u5361\u5bbe\u524d\u4f53\u7684\u94dc\u4e2d\u5fc3\u3002\u800c\u624b\u6027\u6c28\u57fa-\u786b\u8132\u50ac\u5316\u5242\u4fc3\u8fdb\u5bf9\u6620\u9009\u62e9\u6027\u8d28\u5b50\u8f6c\u79fb\u751f\u6210\u63d2\u5165\u4ea7\u7269\u7684\u7acb\u4f53\u4e2d\u5fc3\u3002\u603b\u4e4b\uff0c\u8be5\u53cd\u5e94\u53ef\u4ee5\u5076\u8054\u591a\u79cd\u91cd\u6c2e\u916f\u7c7b\u5316\u5408\u7269\u548c\u80fa\u7c7b\u5316\u5408\u7269\uff0c\u4ee5\u4ea7\u751f\u624b\u6027\u03b1-\u70f7\u57fa-\u03b1-\u6c28\u57fa\u9178\u884d\u751f\u7269\u3002\u7814\u7a76\u6210\u679c\u4ee5\u9898\u76ee\u4e3a<strong>\u201cHighly enantioselective carbene insertion into N-H bonds of aliphatic amines\u201d<\/strong>\u53d1\u8868\u5728\u56fd\u9645\u9876\u7ea7\u671f\u520a<strong>Science<\/strong>\u4e0a\u3002<\/p>\n<p><strong>\u3010\u56fe\u6587\u901f\u9012\u3011<\/strong><\/p>\n<p><strong>\u56fe\u4e00\u3001\u8102\u80aa\u80fa\u4e0e\u5361\u5bbe\u7684N-H\u63d2\u5165\u53cd\u5e94\u7684\u5bf9\u6620\u9009\u62e9\u6027\u7b56\u7565<\/strong><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-190642\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2019\/11\/1-24.jpg\" alt=\"\" width=\"600\" height=\"530\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2019\/11\/1-24.jpg 600w, \/\/m.iemloyee.com\/wp-content\/uploads\/2019\/11\/1-24-300x265.jpg 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/p>\n<p><strong>\u56fe\u4e8c\u3001\u8102\u80aa\u80fa\u548c\u03b1-\u91cd\u6c2e\u916f\u5728\u5bf9\u6620\u9009\u62e9\u6027N-H\u63d2\u5165\u53cd\u5e94\u4e2d\u7684\u4f5c\u7528\u8303\u56f4<\/strong><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-190643\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2019\/11\/2-22.jpg\" alt=\"\" width=\"600\" height=\"694\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2019\/11\/2-22.jpg 600w, \/\/m.iemloyee.com\/wp-content\/uploads\/2019\/11\/2-22-259x300.jpg 259w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/p>\n<p><strong>\u56fe\u4e09\u3001N-H\u63d2\u5165\u4ea7\u7269\u7684\u5408\u6210\u8f6c\u5316<\/strong><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-190644\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2019\/11\/3-22.jpg\" alt=\"\" width=\"600\" height=\"319\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2019\/11\/3-22.jpg 600w, \/\/m.iemloyee.com\/wp-content\/uploads\/2019\/11\/3-22-300x160.jpg 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><br \/>\n <strong>\u56fe\u56db\u3001\u673a\u7406\u7814\u7a76<\/strong><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-190645\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2019\/11\/4-22.jpg\" alt=\"\" width=\"600\" height=\"873\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2019\/11\/4-22.jpg 600w, \/\/m.iemloyee.com\/wp-content\/uploads\/2019\/11\/4-22-206x300.jpg 206w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/p>\n<p><strong>\u6587\u732e\u94fe\u63a5\uff1a<a href=\"https:\/\/science.sciencemag.org\/content\/366\/6468\/990\" target=\"_blank\" rel=\"noopener\">Highly enantioselective carbene insertion into N-H bonds of aliphatic amines<\/a><\/strong>. (<em>Science<\/em>, <strong>2019<\/strong>, DOI: 10.1126\/science.aaw9939)<\/p>\n<p>\u672c\u6587\u7531CQR\u7f16\u8bd1\u3002<\/p>\n<p>\u6b22\u8fce\u5927\u5bb6\u5230\u6750\u6599\u4eba\u5ba3\u4f20\u79d1\u6280\u6210\u679c\u5e76\u5bf9\u6587\u732e\u8fdb\u884c\u6df1\u5165\u89e3\u8bfb\uff0c\u6295\u7a3f\u90ae\u7bb1\uff1atougao@cailiaoren.com.<\/p>\n<p>\u6295\u7a3f\u4ee5\u53ca\u5185\u5bb9\u5408\u4f5c\u53ef\u52a0\u7f16\u8f91\u5fae\u4fe1\uff1acailiaokefu.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u3010\u80cc\u666f\u4ecb\u7ecd\u3011 \u5982\u4eca\uff0c\u5728\u5929\u7136\u4ea7\u7269\u3001\u5408\u6210\u836f\u7269\u548c\u519c\u836f\u4e2d\u65e0\u5904\u4e0d\u5b58\u5728\u5177\u6709\u624b\u6027\u7684\u80fa\u7ed3\u6784\u3002\u636e\u7edf\u8ba1\uff0c\u57282016\u5e74\u6392\u540d\u524d200\u4f4d\u7684\u5904\u65b9\u836f\u4e2d\u7ea6\u670943\uff05\u5305\u542b\u8102\u80aa\u80fa\u90e8\u5206\u3002\u56e0\u6b64\uff0c\u6784\u5efaC-&#8230;<\/p>\n","protected":false},"author":7770,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[215,2],"tags":[4252],"class_list":["post-190641","post","type-post","status-publish","format-standard","hentry","category-jiedu","category-keji","tag-n-h"],"_links":{"self":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts\/190641"}],"collection":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/users\/7770"}],"replies":[{"embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=190641"}],"version-history":[{"count":3,"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts\/190641\/revisions"}],"predecessor-version":[{"id":190649,"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts\/190641\/revisions\/190649"}],"wp:attachment":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=190641"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=190641"},{"taxonomy":"post_tag","embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=190641"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}