{"id":189420,"date":"2019-11-17T06:30:53","date_gmt":"2019-11-16T22:30:53","guid":{"rendered":"\/\/m.iemloyee.com\/?p=189420"},"modified":"2019-11-16T07:57:11","modified_gmt":"2019-11-15T23:57:11","slug":"%e3%80%90%e5%b7%b2%e6%a0%a1%e7%a8%bf%e3%80%91acs-nano%ef%bc%9a%e5%9f%ba%e4%ba%8e%e5%8f%af%e6%b3%a8%e5%b0%84%e7%a3%81%e6%80%a7%e6%b0%b4%e5%87%9d%e8%83%b6%e7%9a%84%e7%a3%81%e6%84%9f%e5%ba%94%e7%83%ad","status":"publish","type":"post","link":"\/\/m.iemloyee.com\/?p=189420","title":{"rendered":"ACS Nano\uff1a\u57fa\u4e8e\u53ef\u6ce8\u5c04\u78c1\u6027\u6c34\u51dd\u80f6\u7684\u78c1\u611f\u5e94\u70ed\u548c\u7eb3\u7c73\u9176\u50ac\u5316\u534f\u540c\u589e\u5f3a\u80bf\u7624\u6cbb\u7597\u6548\u679c"},"content":{"rendered":"

\u3010\u7814\u7a76\u80cc\u666f\u3011<\/strong><\/p>\n

\u78c1\u611f\u5e94\u70ed\u7597\u4f5c\u4e3a\u65b0\u578b\u80bf\u7624\u6cbb\u7597\u7b56\u7565\uff0c\u4e3a\u80bf\u7624\u6cbb\u7597\u5e26\u6765\u4e86\u65b0\u7a81\u7834\uff0c\u5c24\u5176\u662f\u57fa\u4e8e\u78c1\u6027\u7eb3\u7c73\u6750\u6599\u7684\u78c1\u611f\u5e94\u70ed\u7597\uff0c\u5b83\u5229\u7528\u78c1\u6027\u7eb3\u7c73\u9897\u7c92\u4e3a\u78c1\u4ecb\u8d28\uff0c\u4ee5\u9759\u8109\u6ce8\u5c04\u6216\u539f\u4f4d\u4ecb\u5165\u7b49\u65b9\u5f0f\u8fdb\u5165\u80bf\u7624\u7ec4\u7ec7\u540e\uff0c\u5728\u5916\u52a0\u4ea4\u53d8\u78c1\u573a\u7684\u4f5c\u7528\u4e0b\uff0c\u78c1\u4ecb\u8d28\u7531\u4e8e\u5c3c\u5c14\u5f1b\u8c6b(N\u00e9el Relaxation) \u548c\u5e03\u6717\u5f1b\u8c6b(Brownian Relaxation)\u7b49\u6548\u5e94\u800c\u53d1\u70ed\uff0c\u4f7f\u80bf\u7624\u7ec4\u7ec7\u5feb\u901f\u8fbe\u5230\u4e00\u5b9a\u7684\u6e29\u5ea6\u800c\u6740\u706d\u6216\u8bf1\u5bfc\u80bf\u7624\u7ec6\u80de\u51cb\u4ea1\uff0c\u5e76\u4e14\u78c1\u573a\u7a7f\u900f\u6df1\u5ea6\u5f3a\uff0c\u526f\u4f5c\u7528\u5c0f\uff0c\u66f4\u9002\u5408\u6df1\u90e8\u80bf\u7624\u7ec4\u7ec7\u6cbb\u7597\u4e0e\u4e34\u5e8a\u8f6c\u5316\u3002\u4e00\u822c\u6765\u8bf4\uff0c\u80bf\u7624\u78c1\u611f\u5e94\u70ed\u7597\u4e3b\u8981\u6709\u4e24\u4e2a\u6e29\u5ea6\u7a97\u53e3\uff1a\u80bf\u7624\u7ec4\u7ec7\u6e29\u5ea6\u572850\u5ea6\u4ee5\u4e0a\u7684\u78c1\u611f\u5e94\u70ed\u6d88\u878d\u6cbb\u7597\u53ef\u4ee5\u975e\u5e38\u6709\u6548\u3001\u5feb\u901f\u5730\u6d88\u9664\u80bf\u7624\uff0c\u4f46\u4e5f\u5bb9\u6613\u5bf9\u5468\u56f4\u6b63\u5e38\u7ec4\u7ec7\u9020\u6210\u635f\u4f24\u300240-45\u2103\u5de6\u53f3\u7684\u4f4e\u6e29\u8303\u56f4\u53ef\u4ee5\u5728\u6b63\u5e38\u7ec6\u80de\u4e0d\u53d7\u635f\u4f24\u7684\u60c5\u51b5\u4e0b\u8bf1\u5bfc\u764c\u7ec6\u80de\u6b7b\u4ea1\uff0c\u4f46\u80bf\u7624\u7ec6\u80de\u5f80\u5f80\u4f1a\u4ea7\u751f\u5bf9\u70ed\u5e94\u6fc0\u7684\u62b5\u6297\u529b\u800c\u65e0\u6cd5\u5f7b\u5e95\u6740\u6b7b\u80bf\u7624\u7ec6\u80de\u3002\u4e0e\u5176\u4ed6\u6cbb\u7597\u65b9\u5f0f\u76f8\u7ed3\u5408\u53ef\u4ee5\u589e\u5f3a\u70ed\u7597\u7684\u7597\u6548\uff0c\u5982\u5149\u52a8\u529b\u7597\u6cd5\u548c\u5316\u7597\u7b49\uff0c\u7136\u800c\uff0c\u6cbb\u7597\u7cfb\u7edf\u8bbe\u8ba1\u7684\u590d\u6742\u6027\u548c\u968f\u540e\u7684\u80bf\u7624\u590d\u53d1\u4f9d\u7136\u4f7f\u5f97\u6cbb\u7597\u6548\u679c\u4e0d\u5c3d\u5982\u4eba\u610f\u3002\u56e0\u6b64\uff0c\u8fdb\u4e00\u6b65\u63a2\u7d22\u6e29\u548c\u70ed\u7597\u4e0b\u65b0\u7684\u6cbb\u7597\u7b56\u7565\u5177\u6709\u91cd\u8981\u610f\u4e49\u3002<\/p>\n

\u3010\u6210\u679c\u7b80\u4ecb\u3011<\/strong><\/p>\n

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\u3010\u56fe\u6587\u5bfc\u8bfb\u3011<\/strong><\/p>\n

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\"\"<\/p>\n

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\"\"<\/p>\n

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\"\"<\/p>\n

\uff08a\uff09\u03b1-CD\uff0cPFOB@DSPE-MPEG2000\u548cPLGA-MPEG\u7eb3\u7c73\u80f6\u56ca\u4ee5\u53ca\u51b7\u51bb\u5e72\u71e5\u7684MHZ\u6837\u54c1\u7684XRD\u66f2\u7ebf\u3002<\/p>\n

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\"\"<\/p>\n

\uff08a\uff09\u6bd4\u8f83\u4e09\u79cd\u4e0d\u540c\u7684\u8868\u9762\u6539\u6027\u7684Fe3<\/sub>O4<\/sub>\u7eb3\u7c73\u9897\u7c92\u7684\u50ac\u5316\u6027\u80fd\u3002<\/p>\n

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\u56fe\u4e94\uff1a<\/strong>MHZ<\/strong>\u5728\u80bf\u7624\u7ec4\u7ec7\u4e2d\u7684\u79bb\u4f53\u6269\u6563\u6027\u80fd<\/strong><\/p>\n

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\"\"<\/p>\n

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\"\"<\/p>\n

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\uff08c\uff09HSP 70\u5728\u4e09\u7ec4\u80bf\u7624\u7ec4\u7ec7\u4e2d\u7684\u514d\u75ab\u7ec4\u5316\u53ca\u5b9a\u91cf\u5bf9\u6bd4\u3002<\/p>\n

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\"\"<\/p>\n

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\uff08b\uff09\u7ecf\u8fc7\u4e0d\u540c\u6cbb\u7597\u8fc7\u7a0b\u540e\uff0c4T1\u8377\u7624\u5c0f\u9f20\u7684\u957f\u671f\u5b58\u6d3b\u7387\u3002<\/p>\n

\u3010\u7ed3\u8bba\u5c55\u671b\u3011<\/strong><\/p>\n

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\u6587\u732e\u94fe\u63a5\uff1aEnhanced Tumor Synergistic Therapy by Injectable Magnetic Hydrogel Mediated Generation of Hyperthermia and Highly Toxic Reactive Oxygen Species<\/a>(ACS Nano <\/em>2019<\/strong>, DOI: 10.1021\/acsnano.9b06134)<\/p>\n

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\u8bfe\u9898\u7ec4\u4e3b\u9875\uff1ahttp:\/\/lbmd.seu.edu.cn\/nano\/<\/a><\/strong><\/p>\n

\u56e2\u961f\u5728\u76f8\u5173\u9886\u57df\u7814\u7a76\u6587\u732e\uff1a<\/p>\n

\u80bf\u7624\u78c1\u611f\u5e94\u70ed\u6d88\u878d\uff1aWu, Haoan, et al. “Injectable thermosensitive magnetic nanoemulsion hydrogel for multimodal-imaging-guided accurate thermoablative cancer therapy.” Nanoscale 9.42 (2017): 16175-16182.<\/p>\n

\u78c1\u611f\u5e94\u70ed\u5316\u7597\u6e05\u9664\u80bf\u7624\u672f\u540e\u6b8b\u4f59\uff1aWu, Haoan, et al. “Injectable magnetic supramolecular hydrogel with magnetocaloric liquid-conformal property prevents post-operative recurrence in a breast cancer model.” Acta biomaterialia 74 (2018): 302-311.<\/p>\n

\u56db\u6c27\u5316\u4e09\u94c1\u7eb3\u7c73\u9897\u7c92\u53cc\u9176\u6d3b\u6027\uff1aChen, Zhongwen, et al. “Dual enzyme-like activities of iron oxide nanoparticles and their implication for diminishing cytotoxicity.” Acs Nano 6.5 (2012): 4001-4012.<\/p>\n

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