{"id":185059,"date":"2019-09-05T08:05:46","date_gmt":"2019-09-05T00:05:46","guid":{"rendered":"\/\/m.iemloyee.com\/?p=185059"},"modified":"2019-10-18T18:25:47","modified_gmt":"2019-10-18T10:25:47","slug":"%e4%bb%8a%e6%97%a5%e6%9c%80%e6%96%b0nature-n-cf3%e5%8c%96%e9%85%b0%e8%83%ba%e5%8c%96%e5%90%88%e7%89%a9%e7%9a%84%e5%90%88%e6%88%90","status":"publish","type":"post","link":"\/\/m.iemloyee.com\/?p=185059","title":{"rendered":"\u4eca\u65e5\u6700\u65b0Nature: N\u2013CF3\u5316\u9170\u80fa\u5316\u5408\u7269\u7684\u5408\u6210"},"content":{"rendered":"<p><strong>\u3010\u5f15\u8a00\u3011<\/strong><\/p>\n<p>\u9170\u80fa\u53ca\u5176\u7fb0\u57fa\u884d\u751f\u7269\u5728\u7269\u7406\u548c\u751f\u547d\u79d1\u5b66\u4e2d\u4e00\u76f4\u5360\u636e\u7740\u91cd\u8981\u7684\u4f4d\u7f6e\u3002\u4f5c\u4e3a\u5173\u952e\u7684\u6784\u5efa\u6a21\u5757\uff0c\u9170\u80fa\u7684\u7a33\u5b9a\u6027\u548c\u6784\u8c61\u6df1\u523b\u5f71\u54cd\u7740\u591a\u80bd\u548c\u86cb\u767d\u8d28\u7684\u7ed3\u6784\u548c\u529f\u80fd\u3002\u7531\u4e8e\u9170\u80fa\u7684\u666e\u9002\u6027\uff0c\u5f00\u53d1\u80fd\u591f\u5bf9\u5176\u8fdb\u884c\u6539\u6027\u7684\u6280\u672f\u5728\u836f\u7269\u3001\u519c\u4e1a\u548c\u6750\u6599\u7b49\u9886\u57df\u5177\u6709\u91cd\u5927\u7684\u610f\u4e49\u3002\u76ee\u524d\uff0c\u6c1f\u5316\u4f5c\u7528\u4ee5\u53ca\u4f4d\u70b9\u7279\u5f02\u6027\u7684\u7532\u57fa\u5316\u53cd\u5e94\u5206\u522b\u662f\u80fd\u591f\u6539\u53d8\u6709\u673a\u5206\u5b50\u7406\u5316\u6027\u8d28\u7684\u4e3b\u8981\u624b\u6bb5\u3002\u7136\u800c\uff0c\u7531\u4e8e\u7f3a\u4e4f\u6709\u6548\u7684\u5408\u6210\u624b\u6bb5\uff0c\u540c\u65f6\u7ed3\u5408\u7532\u57fa\u5316\u548c\u6c1f\u5316\u4f5c\u7528\u7684\u6c1f\u7532\u57fa\u5316\uff08<em>N<\/em>\u2013CF<sub>3<\/sub>\uff09\u7fb0\u57fa\u6a21\u4f53\uff08motif\uff09\u8fd8\u5c1a\u672a\u88ab\u5f00\u53d1\u51fa\u6765\u3002<\/p>\n<p>\u3010<strong>\u6210\u679c\u7b80\u4ecb<\/strong>\u3011<\/p>\n<p><strong>\u5fb7\u56fd\u4e9a\u741b\u5de5\u4e1a\u5927\u5b66\u7684<\/strong><strong>F. Schoenebeck<\/strong>\u901a\u8baf\u4f5c\u8005\uff09\u7b49\u4eba\u62a5\u9053\u4e86\u80fd\u591f\u83b7\u5f97\u9170\u80fa\u53ca\u5176\u76f8\u5173\u7fb0\u57fa\u5316\u5408\u7269\u7684\u6c1f\u7532\u57fa\u7c7b\u4f3c\u7269\u7684\u65b9\u6cd5\u3002\u7814\u7a76\u9996\u5148\u53d1\u73b0\u5f02\u786b\u6c30\u9178\u916f\u4e0e\u6c1f\u5316\u94f6\u4f5c\u7528\u80fd\u591f\u8fdb\u884c\u8131\u786b\u4f5c\u7528\u800c\u751f\u6210\u542b\u6c1f\u7532\u57fa\u7684\u4e9a\u80fa\u5316\u5408\u7269\u3002\u8fd9\u5176\u4e2d\uff0c\u6c1f\u5316\u94f6\u7684\u52a0\u5165\u80fd\u591f\u4ea7\u751f\u4eb2\u6838\u884d\u751f\u7269\u3002\u8fdb\u4e00\u6b65\u5730\uff0c\u7814\u7a76\u4eba\u5458\u5229\u7528\u56fa\u4f53\u8bd5\u5242\u53cc(\u4e09\u6c2f\u7532\u57fa)\u78b3\u9178\u916f\uff08BTC\uff09\u4f5c\u4e3a\u7fb0\u57fa\u4eb2\u7535\u8bd5\u5242\u6210\u529f\u6355\u83b7\u4e86\u8fd9\u4e00\u4eb2\u6838\u884d\u751f\u7269\uff0c\u5e76\u6700\u7ec8\u4ea7\u751f\u6c1f\u7532\u57fa\u5316\u7684\u7fb0\u57fa\u6a21\u4f53\u3002\u7279\u522b\u662f\u5728\u542b\u6709\u8054\u82ef\u5f02\u786b\u6c30\u9178\u3001BTC\u4ee5\u53ca\u6c1f\u5316\u94f6\u7684\u4e59\u8148\u6eb6\u6db2\u4e2d\uff0c\u7ecf\u8fc716h\u7684\u53cd\u5e94\uff0c\u5176\u6c1f\u7532\u57fa\u5316\u7fb0\u57fa\u6c1f\u5316\u7269\u7684\u4ea7\u7387\u9ad8\u8fbe98%\uff0c\u5e76\u4e14\u8fd9\u4e00\u4ea7\u7269\u5728\u6e7f\u5ea6\u548c\u6709\u6c27\u73af\u5883\u4e2d\u8868\u73b0\u51fa\u4f18\u5f02\u7684\u7a33\u5b9a\u6027\u3002\u8be5\u7814\u7a76\u8ba4\u4e3a\uff0c\u8fd9\u4e00\u65b9\u6cd5\u53ef\u4ee5\u7b80\u5355\u6709\u6548\u5730\u5408\u6210\u6c1f\u7532\u57fa\u5316\u7684\u9170\u80fa\u3001\u6c28\u57fa\u7532\u9178\u76d0\u4ee5\u53ca\u5c3f\u7d20\u7b49\u5316\u5408\u7269\u30022019\u5e7409\u670804\u65e5\uff0c\u76f8\u5173\u6210\u679c\u4ee5\u9898\u4e3a\u201c<strong>Straightforward access to N-trifluoromethyl amides, carbamates, thiocarbamates and ureas<\/strong>\u201d\u7684\u6587\u7ae0\u5728\u7ebf\u53d1\u8868\u5728<strong>Nature<\/strong>\u4e0a\u3002<\/p>\n<p>\u3010<strong>\u56fe\u6587\u5bfc\u8bfb<\/strong>\u3011<\/p>\n<p><strong>\u56fe1 <\/strong><strong>\u9170\u80fa\u53ca\u5176\u76f8\u5173\u5316\u5408\u7269<\/strong><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-185060\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2019\/09\/1-4.jpg\" alt=\"\" width=\"579\" height=\"475\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2019\/09\/1-4.jpg 579w, \/\/m.iemloyee.com\/wp-content\/uploads\/2019\/09\/1-4-300x246.jpg 300w\" sizes=\"(max-width: 579px) 100vw, 579px\" \/><\/p>\n<p><strong>\u56fe<\/strong><strong>2<\/strong> <strong>\u6c1f\u7532\u57fa\u5316\u7fb0\u57fa\u6a21\u4f53\u7684\u5408\u6210<\/strong><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-185061\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2019\/09\/2-3.jpg\" alt=\"\" width=\"580\" height=\"533\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2019\/09\/2-3.jpg 580w, \/\/m.iemloyee.com\/wp-content\/uploads\/2019\/09\/2-3-300x276.jpg 300w\" sizes=\"(max-width: 580px) 100vw, 580px\" \/><\/p>\n<p><strong>\u56fe3\u6c1f\u7532\u57fa\u5316\uff08<em>N<\/em>\u2013CF<sub>3<\/sub>\uff09\u9170\u80fa\u7684\u5408\u6210<\/strong><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-185062\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2019\/09\/3-3.jpg\" alt=\"\" width=\"471\" height=\"546\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2019\/09\/3-3.jpg 471w, \/\/m.iemloyee.com\/wp-content\/uploads\/2019\/09\/3-3-259x300.jpg 259w\" sizes=\"(max-width: 471px) 100vw, 471px\" \/><\/p>\n<p><strong>\u56fe<\/strong><strong>4<\/strong> <strong>\u6c1f\u7532\u57fa\u5316\uff08<\/strong><strong><em>N<\/em><\/strong><strong>\u2013CF<sub>3<\/sub><\/strong><strong>\uff09\u884d\u751f\u7269\u7684\u5408\u6210<\/strong><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-185063\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2019\/09\/4-3.jpg\" alt=\"\" width=\"428\" height=\"546\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2019\/09\/4-3.jpg 428w, \/\/m.iemloyee.com\/wp-content\/uploads\/2019\/09\/4-3-235x300.jpg 235w\" sizes=\"(max-width: 428px) 100vw, 428px\" \/><\/p>\n<p>\u6587\u732e\u94fe\u63a5\uff1a<a href=\"https:\/\/www.nature.com\/articles\/s41586-019-1518-3\" target=\"_blank\" rel=\"noopener\">Straightforward access to N-trifluoromethyl amides, carbamates, thiocarbamates and ureas<\/a>\uff08Nature, 2019, DOI: 10.1038\/s41586-019-1518-3\uff09<\/p>\n<p>\u672c\u6587\u7531\u6750\u6599\u4eba\u5b66\u672f\u7ec4NanoCJ\u4f9b\u7a3f\u3002<\/p>\n<p>\u6750\u6599\u725b\u7f51\u4e13\u6ce8\u4e8e\u8ddf\u8e2a\u6750\u6599\u9886\u57df\u79d1\u6280\u53ca\u884c\u4e1a\u8fdb\u5c55\uff0c\u6b22\u8fce\u5927\u5bb6\u5230\u6750\u6599\u4eba\u5ba3\u4f20\u79d1\u6280\u6210\u679c\u5e76\u5bf9\u6587\u732e\u8fdb\u884c\u6df1\u5165\u89e3\u8bfb\uff0c\u6295\u7a3f\u90ae\u7bb1tougao@cailiaoren.com\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u3010\u5f15\u8a00\u3011 \u9170\u80fa\u53ca\u5176\u7fb0\u57fa\u884d\u751f\u7269\u5728\u7269\u7406\u548c\u751f\u547d\u79d1\u5b66\u4e2d\u4e00\u76f4\u5360\u636e\u7740\u91cd\u8981\u7684\u4f4d\u7f6e\u3002\u4f5c\u4e3a\u5173\u952e\u7684\u6784\u5efa\u6a21\u5757\uff0c\u9170\u80fa\u7684\u7a33\u5b9a\u6027\u548c\u6784\u8c61\u6df1\u523b\u5f71\u54cd\u7740\u591a\u80bd\u548c\u86cb\u767d\u8d28\u7684\u7ed3\u6784\u548c\u529f\u80fd\u3002\u7531\u4e8e\u9170\u80fa\u7684\u666e\u9002\u6027\uff0c&#8230;<\/p>\n","protected":false},"author":1076,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[215],"tags":[],"class_list":["post-185059","post","type-post","status-publish","format-standard","hentry","category-jiedu"],"_links":{"self":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts\/185059"}],"collection":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/users\/1076"}],"replies":[{"embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=185059"}],"version-history":[{"count":2,"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts\/185059\/revisions"}],"predecessor-version":[{"id":185067,"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts\/185059\/revisions\/185067"}],"wp:attachment":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=185059"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=185059"},{"taxonomy":"post_tag","embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=185059"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}