{"id":171093,"date":"2019-04-01T06:37:48","date_gmt":"2019-03-31T22:37:48","guid":{"rendered":"\/\/m.iemloyee.com\/?p=171093"},"modified":"2019-03-31T22:10:32","modified_gmt":"2019-03-31T14:10:32","slug":"%e5%b7%b2%e5%8f%91%e9%80%81%e4%b8%a4%e6%ac%a1%e9%82%ae%e4%bb%b6%e9%83%bd%e6%9c%aa%e5%9b%9e%e5%a4%8d-%e4%b8%ad%e7%a7%91%e9%99%a2%e9%95%bf%e6%98%a5%e5%ba%94%e5%8c%96%e6%89%80-%e6%9b%b2%e6%99%93%e5%88%9a","status":"publish","type":"post","link":"\/\/m.iemloyee.com\/?p=171093","title":{"rendered":"\u4e2d\u79d1\u9662\u957f\u6625\u5e94\u5316\u6240 \u66f2\u6653\u521a\u56e2\u961f Angew: 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Heterogeneous MOF-Cu Catalyst Used for In Vivo Drug Synthesis at Targeted Subcellular Organelles\u201d<\/strong>\u53d1\u5e03\u5728\u56fd\u9645\u8457\u540d\u671f\u520a<strong>Angew. Chem. Int. Ed.<\/strong>\u4e0a\u3002<\/p>\n<p><strong>\u3010\u56fe\u6587\u89e3\u8bfb\u3011<\/strong><\/p>\n<p><strong>\u56fe\u4e00\u3001\u6784\u5efa\u9776\u5411\u7ebf\u7c92\u4f53\u7684CuAAC\u53cd\u5e94\u50ac\u5316\u5242\u548c\u4e9a\u7ec6\u80de\u5668\u4e0b\u539f\u4f4d\u836f\u7269\u5408\u6210<\/strong><br \/>\n <img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-171095\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2019\/03\/1-35.jpg\" alt=\"\" width=\"600\" height=\"585\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2019\/03\/1-35.jpg 600w, \/\/m.iemloyee.com\/wp-content\/uploads\/2019\/03\/1-35-300x293.jpg 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" 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\/>\uff08a\uff09MOF-Cu\u50ac\u5316\u9999\u8c46\u7d20\u53e0\u6c2e\u548c\u82ef\u4e59\u7094\u751f\u6210\u9999\u8c46\u7d20\u8367\u5149\u5206\u5b50\u76841, 3-\u5076\u6781\u73af\u52a0\u6210\u53cd\u5e94\u7684\u793a\u610f\u56fe\uff1b<\/p>\n<p>\uff08b\uff09\u6ca1\u6709\uff08\u9ed1\u7ebf\uff09\u548c\u6709\uff08\u7ea2\u7ebf\uff09MOF-Cu\u50ac\u5316\u5242\u7684\u70b9\u51fb\u53cd\u5e94\u7684\u8367\u5149\u5149\u8c31\u548c\u76f8\u5e94\u7684\u5b9e\u9a8c\u8367\u5149\u7167\u7247\uff08\u63d2\u5165\u7167\u7247\uff09\uff1b<\/p>\n<p>\uff08c\uff09\u5728\u6ca1\u6709\u50ac\u5316\u5242\u7684\u53cd\u5e94\u7684\u4e0d\u540c\u65f6\u95f4\uff080-120 min\uff09\u4e0b\u8367\u5149\u5149\u8c31\u7684\u53d8\u5316\uff1b<\/p>\n<p>\uff08d\uff09\u6709MOF-Cu\u50ac\u5316\u5242\u7684\u53cd\u5e94\u7684\u4e0d\u540c\u65f6\u95f4\uff080-120 min\uff09\u4e0b\u8367\u5149\u5149\u8c31\u7684\u53d8\u5316\u3002<\/p>\n<p><strong>\u56fe\u4e09\u3001 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MOF-Cu\u50ac\u5316\u5242\u5904\u7406MCF-7\u7ec6\u80de\u7684\u8367\u5149\u56fe\u50cf\u3002<\/p>\n<p><strong>\u56fe\u56db\u3001\u5236\u5907\u7684\u9776\u5411\u6027\u94dc\u50ac\u5316\u5242\u5728\u7ebf\u7c92\u4f53\u4e2d\u539f\u4f4d\u5408\u6210\u767d\u85dc\u82a6\u9187\u884d\u751f\u7269<\/strong><br \/>\n <img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-171098\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2019\/03\/4-33.jpg\" alt=\"\" width=\"600\" height=\"678\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2019\/03\/4-33.jpg 600w, \/\/m.iemloyee.com\/wp-content\/uploads\/2019\/03\/4-33-265x300.jpg 265w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/>\uff08a\uff09\u7ebf\u7c92\u4f53\u4e2d\u767d\u85dc\u82a6\u9187\u884d\u751f\u7269\u7684\u539f\u4f4d\u5408\u6210\u793a\u610f\u56fe\uff1b<\/p>\n<p>\uff08b\uff09 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href=\"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/anie.201901760\" target=\"_blank\" rel=\"noopener\">Biocompatible Heterogeneous MOF-Cu Catalyst Used for In Vivo Drug Synthesis at Targeted Subcellular Organelles<\/a><\/strong>\uff08Angew. Chem. Int. Ed., <strong>2019<\/strong>, DOI:10.1002\/anie.201901760\uff09<\/p>\n<p>\u672c\u6587\u7531\u6750\u6599\u4ebaCQR\u7f16\u8bd1\uff0c\u6750\u6599\u4eba\u6574\u7406\u3002<\/p>\n<p>\u6b22\u8fce\u5927\u5bb6\u5230\u6750\u6599\u4eba\u5ba3\u4f20\u79d1\u6280\u6210\u679c\u5e76\u5bf9\u6587\u732e\u8fdb\u884c\u6df1\u5165\u89e3\u8bfb\uff0c\u6295\u7a3f\u90ae\u7bb1\uff1atougao@cailiaoren.com.<\/p>\n<p>\u6295\u7a3f\u4ee5\u53ca\u5185\u5bb9\u5408\u4f5c\u53ef\u52a0\u7f16\u8f91\u5fae\u4fe1\uff1acailiaokefu.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u3010\u5f15\u8a00\u3011 \u751f\u7269\u6b63\u4ea4\u53cd\u5e94\u662f\u6307\u90a3\u4e9b\u80fd\u591f\u5728\u6d3b\u4f53\u7ec6\u80de\u6216\u7ec4\u7ec7\u4e2d\u4e14\u5728\u4e0d\u5e72\u6270\u751f\u7269\u81ea\u8eab\u751f\u5316\u53cd\u5e94\u6761\u4ef6\u4e0b\u53ef\u4ee5\u8fdb\u884c\u7684\u5316\u5b66\u53cd\u5e94\u3002\u5176\u4e2d\uff0c\u751f\u7269\u6b63\u4ea4\u53cd\u5e94\u7684\u70b9\u51fb\u5316\u5b66\u7531\u4e8e\u5177\u6709\u8f83\u9ad8\u7684\u9009\u62e9\u6027\u548c\u53cd\u5e94\u6548&#8230;<\/p>\n","protected":false},"author":7770,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[215,2],"tags":[3960],"class_list":["post-171093","post","type-post","status-publish","format-standard","hentry","category-jiedu","category-keji","tag-mof-cu"],"_links":{"self":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts\/171093"}],"collection":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/users\/7770"}],"replies":[{"embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=171093"}],"version-history":[{"count":2,"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts\/171093\/revisions"}],"predecessor-version":[{"id":171558,"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts\/171093\/revisions\/171558"}],"wp:attachment":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=171093"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=171093"},{"taxonomy":"post_tag","embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=171093"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}