{"id":169132,"date":"2019-03-14T06:30:59","date_gmt":"2019-03-13T22:30:59","guid":{"rendered":"\/\/m.iemloyee.com\/?p=169132"},"modified":"2019-03-13T16:52:01","modified_gmt":"2019-03-13T08:52:01","slug":"%e5%b7%b2%e6%a0%a1%e7%a8%bf%e4%bb%b6-%e4%b8%ad%e7%a7%91%e9%99%a2%e8%bf%87%e7%a8%8b%e6%89%80-%e9%97%ab%e5%ad%a6%e6%b5%b7%e5%9b%a2%e9%98%9fam-%e5%86%85%e6%ba%90%e6%80%a7%e8%83%86%e7%bb%bf%e7%b4%a0","status":"publish","type":"post","link":"\/\/m.iemloyee.com\/?p=169132","title":{"rendered":"\u4e2d\u79d1\u9662\u8fc7\u7a0b\u6240 \u95eb\u5b66\u6d77\u56e2\u961fAM: 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BV)\u5f00\u53d1\u7684\u4e00\u79cd\u5149\u70ed\u7eb3\u7c73\u5236\u5242\uff0c\u4e3a\u80bf\u7624\u8bca\u65ad\u6cbb\u7597\u63d0\u4f9b\u4e86\u9ad8\u6548\u3001\u4ee3\u8c22\u660e\u786e\u7684\u5019\u9009\u836f\u7269\u3002\u7814\u7a76\u7ed3\u679c\u8868\u660e\uff0c\u901a\u8fc7\u8d85\u5206\u5b50\u7ec4\u88c5\u4ee5\u53ca\u91d1\u5c5e\u79bb\u5b50\u914d\u4f4d\u7ec4\u88c5\uff0c\u77ed\u80bd\u3001BV\u4e0e\u529f\u80fd\u6027\u91d1\u5c5e\u79bb\u5b50\u7ec4\u88c5\u5f62\u6210\u5177\u6709\u5f3aNIR\u5438\u6536\u3001\u5149\u7a33\u5b9a\u6027\u3001\u80f6\u4f53\u7a33\u5b9a\u6027\u548c\u9ad8\u5149\u70ed\u8f6c\u5316\u6548\u7387\u7684\u5149\u70ed\u7eb3\u7c73\u5236\u5242\u3002\u5c0f\u9f20\u4f53\u5185\u5b9e\u9a8c\u8bc1\u660e\uff0cBV\u7eb3\u7c73\u5236\u5242\u5728\u80bf\u7624\u5904\u9009\u62e9\u6027\u7684\u79ef\u7d2f\uff0c\u5728\u6e29\u548c\u7684NIR\u7167\u5c04\u4e0b\u80bf\u7624\u5c40\u90e8\u5347\u6e29\uff0c\u8fdb\u800c\u5b9e\u73b0\u80bf\u7624\u7ec6\u80de\u6d88\u878d\uff0c\u5176\u4ee3\u8c22\u673a\u5236\u660e\u786e\u4e14\u65e0\u660e\u663e\u6bd2\u526f\u4f5c\u7528\u3002\u6b64\u5916\uff0c\u57fa\u4e8eBV\u7eb3\u7c73\u5236\u5242\u7684\u5149\u58f0\u548c\u78c1\u5171\u632f\u6210\u50cf\uff0c\u5b9e\u73b0\u4e86\u80bf\u7624\u7684\u53ef\u89c6\u5316PTT\u3002BV\u7eb3\u7c73\u5236\u5242\u6709\u4f18\u5f02\u7684\u751f\u7269\u5b89\u5168\u6027\uff0c\u5c06\u975e\u5e38\u6709\u52a9\u4e8e\u7cbe\u51c6\u533b\u5b66\u7684\u8fdb\u4e00\u6b65\u53d1\u5c55\u3002\u7814\u7a76\u6210\u679c\u4ee5\u9898\u4e3a<strong>\u201cSelf-Assembling Endogenous Biliverdin as a Versatile Near-Infrared Photothermal Nanoagent for Cancer Theranostics\u201d<\/strong>\u53d1\u5e03\u5728\u56fd\u9645\u8457\u540d\u671f\u520a<strong>Adv. Mater.<\/strong>\u4e0a\u3002<\/p>\n<p><strong>\u3010\u56fe\u6587\u5bfc\u8bfb\u3011<\/strong><\/p>\n<p><strong>\u56fe\u4e00\u3001\u7528\u4e8e\u591a\u6a21\u6001\u80bf\u7624\u6210\u50cf\u548cNIR\u5149\u70ed\u6740\u6b7b\u80bf\u7624\u7684BV\u7eb3\u7c73\u5242<\/strong><br \/>\n <img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-169133\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2019\/03\/1-13.jpg\" alt=\"\" width=\"600\" height=\"596\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2019\/03\/1-13.jpg 600w, \/\/m.iemloyee.com\/wp-content\/uploads\/2019\/03\/1-13-150x150.jpg 150w, \/\/m.iemloyee.com\/wp-content\/uploads\/2019\/03\/1-13-300x298.jpg 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/>\uff08a\uff09\u5185\u6e90\u6027BV\u7684\u4ee3\u8c22\u9014\u5f84\uff1b<\/p>\n<p>\uff08b\uff09\u5355\u5206\u5b50BV\u53ca\u57fa\u4e8eBV\u7684\u7eb3\u7c73\u6750\u6599\uff08ZB NPs, ZBMn NPs\uff09\u7684\u7d2b\u5916-\u53ef\u89c1\u5438\u6536\u5149\u8c31\uff1b<\/p>\n<p>\uff08c\uff09BV\u3001\u77ed\u80bd\u548c\u91d1\u5c5e\u79bb\u5b50\u7684\u8d85\u5206\u5b50\u81ea\u7ec4\u88c5\u7b56\u7565\uff1b<\/p>\n<p>\uff08d\uff09BV\u7eb3\u7c73\u5242\u7684\u5c3a\u5bf8\u5206\u5e03\uff1b<\/p>\n<p>\uff08e\uff09\u591a\u6a21\u5f0f\u80bf\u7624\u6210\u50cf\u548cNIR\u80bf\u7624\u6cbb\u7597\uff1b<\/p>\n<p>\uff08f, g\uff09ZB NPs\u7684TEM\uff08f\uff09\u548cSEM\uff08g\uff09\u56fe\u50cf\uff1b<\/p>\n<p>\uff08h, i\uff09ZBMn NPs\u7684TEM\uff08h\uff09\u548cSEM\uff08i\uff09\u56fe\u50cf\u3002<\/p>\n<p><strong>\u56fe\u4e8c\u3001\u751f\u7269\u7a33\u5b9a\u6027\u548c\u4f53\u5916\u7ec6\u80de\u5b58\u6d3b\u7387<\/strong><br \/>\n <img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-169135\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2019\/03\/2.webp_.jpg\" alt=\"\" width=\"600\" height=\"433\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2019\/03\/2.webp_.jpg 600w, \/\/m.iemloyee.com\/wp-content\/uploads\/2019\/03\/2.webp_-300x217.jpg 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/>\uff08a\uff09ZBMn NPs\u5728\u751f\u7406\u57f9\u517b\u57fa\u4e2d\u5b75\u80b2\u4e00\u5b9a\u65f6\u95f4\u540e\u7684\u7d2b\u5916-\u53ef\u89c1\u5149\u8c31\uff1b<\/p>\n<p>\uff08b\uff09ZBMn NPs\u5728\u751f\u7406\u57f9\u517b\u57fa\u4e2d\u5b75\u80b2\u4e00\u5b9a\u65f6\u95f4\u540e\u7684DLS\u56fe\uff1b<\/p>\n<p>\uff08c\uff09ZBMn NPs\u62b5\u6297\u7a00\u91ca\u80fd\u529b\u7684DLS\u56fe\uff1b<\/p>\n<p>\uff08d\uff09\u57fa\u4e8eBV\u7684\u7eb3\u7c73\u9897\u7c92\u5bf9MCF-7\u7ec6\u80de\u7684\u6697\u6bd2\u6027\u53ca\u5149\u6bd2\u6027\u3002<\/p>\n<p><strong>\u56fe\u4e09\u3001ZB NPs\u548cZBMn NPs\u7684\u4f53\u5916\u5149\u70ed\u6027\u80fd<\/strong><br \/>\n <img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-169136\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2019\/03\/3.webp_.jpg\" alt=\"\" width=\"600\" height=\"300\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2019\/03\/3.webp_.jpg 600w, \/\/m.iemloyee.com\/wp-content\/uploads\/2019\/03\/3.webp_-300x150.jpg 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/>\uff08a\uff09\u5728\u6fc0\u5149\u7167\u5c04\uff08730 nm, 0.3 W cm<sup>-2<\/sup>\uff09\u4e0b\uff0c10 min \u5185ZB NPs\u3001ZBMn NPs\u548cH<sub>2<\/sub>O\u7684\u5347\u6e29\u60c5\u51b5<\/p>\n<p>\uff08b\uff09\u4e0d\u540c\u6d53\u5ea6\u7684BV\u7ec4\u88c5\u6210\u7684\u7eb3\u7c73\u9897\u7c92\u5728\u6fc0\u5149\u7167\u5c04\uff08730 nm, 0.3 W cm<sup>-2<\/sup>\uff09\u4e0b\u7684\u5347\u6e29\u60c5\u51b5\uff1b<\/p>\n<p>\uff08c\uff09\u4e0d\u540c\u6fc0\u5149\u5f3a\u5ea6\u7167\u5c04\u4e0b\uff0cZB NPs\u548cZBMn NPs\u7684\u6e29\u5ea6\u53d8\u5316\u3002<\/p>\n<p>\uff08d, e\uff09ZB NPs\uff08d\uff09\u548cZBMn NPs\uff08e\uff09\u7684\u5149\u7167\u5faa\u73af\u5347\u6e29\u66f2\u7ebf\uff1b<\/p>\n<p>\uff08f\uff09\u5149\u70ed\u6750\u6599\u5149\u70ed\u8f6c\u6362\u6548\u7387\u62df\u5408\u66f2\u7ebf\u3002<\/p>\n<p><strong>\u56fe\u56db\u3001ZB NPs\u548cZBMn NPs\u7684\u52a8\u7269\u4f53\u5185\u5b9e\u9a8c<\/strong><br \/>\n <img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-169137\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2019\/03\/4.webp_.jpg\" alt=\"\" width=\"600\" height=\"589\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2019\/03\/4.webp_.jpg 600w, \/\/m.iemloyee.com\/wp-content\/uploads\/2019\/03\/4.webp_-300x295.jpg 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/>\uff08a\uff09ZB NPs\u548cZBMn NPs\u7684\u4f53\u5185\u836f\u7269\u52a8\u529b\u5b66\u5b9e\u9a8c\uff1b<\/p>\n<p>\uff08b, c\uff09ZB NPs\uff08b\uff09\u548cZBMn 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href=\"https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1002\/adma.201900822\" target=\"_blank\" rel=\"noopener\">Self-Assembling Endogenous Biliverdin as a Versatile Near-Infrared Photothermal Nanoagent for Cancer Theranostics<\/a><\/strong>\uff08Adv. Mater., <strong>2019<\/strong>, DOI: 10.1002\/adma.201900822\uff09<\/p>\n<p style=\"text-align: center;\"><strong>\u901a\u8baf\u4f5c\u8005\u7b80\u4ecb<\/strong><\/p>\n<p><strong>\u95eb\u5b66\u6d77\uff0c\u4e2d\u56fd\u79d1\u5b66\u9662\u8fc7\u7a0b\u5de5\u7a0b\u7814\u7a76\u6240\u7814\u7a76\u5458\uff0c\u535a\u58eb\u751f\u5bfc\u5e08\uff0c\u751f\u5316\u5de5\u7a0b\u56fd\u5bb6\u91cd\u70b9\u5b9e\u9a8c\u5ba4\u526f\u4e3b\u4efb\u3001\u4ecb\u5c3a\u5ea6\u79d1\u5b66\u7814\u7a76\u4e2d\u5fc3\u526f\u4e3b\u4efb<\/strong>\u3002\u56fd\u5bb6\u201c\u9752\u5e74\u5343\u4eba\u8ba1\u5212\u201d\u5165\u9009\u8005\uff0c\u56fd\u5bb6\u81ea\u7136\u79d1\u5b66\u57fa\u91d1\u59d4\u201c\u4f18\u79c0\u9752\u5e74\u201d\u79d1\u5b66\u57fa\u91d1\u83b7\u5f97\u8005\uff0c\u4e2d\u56fd\u5316\u5b66\u4f1a\u751f\u7269\u7269\u7406\u5316\u5b66\u4e13\u4e1a\u59d4\u5458\u4f1a\u3001\u9752\u5e74\u5de5\u4f5c\u8005\u59d4\u5458\u4f1a\u59d4\u5458\u30022008\u5e74\u4e8e\u4e2d\u56fd\u79d1\u5b66\u9662\u5316\u5b66\u7814\u7a76\u6240\u83b7\u5f97\u535a\u58eb\u5b66\u4f4d\uff0c\u4e4b\u540e\u5728\u5fb7\u56fd\u9a6c\u666e\u80f6\u4f53\u4e0e\u754c\u9762\u7814\u7a76\u6240\u5148\u540e\u4ece\u4e8b\u535a\u58eb\u540e\u548c\u6d2a\u5821\u5b66\u8005\u7814\u7a76\u5de5\u4f5c\u30022013\u5e74\u56de\u56fd\u52a0\u5165\u4e2d\u79d1\u9662\u8fc7\u7a0b\u5de5\u7a0b\u7814\u7a76\u6240\u3002<strong>\u4e3b\u8981\u4ece\u4e8b\u751f\u7269\u5206\u5b50\u7ec4\u88c5\u548c\u5de5\u7a0b\u5316\u7814\u7a76\uff0c\u6d89\u53ca\uff1a\u80bd\u3001\u86cb\u767d\u8d28\u7b49\u751f\u7269\u5206\u5b50\u81ea\u7ec4\u88c5\u548c\u8d85\u5206\u5b50\u4f5c\u7528\u673a\u7406\uff0c\u751f\u7269\u6750\u6599\u53ef\u63a7\u5236\u5907\u6280\u672f\uff1b\u7eb3\u7c73\u836f\u7269\u548c\u5242\u578b\u3001\u75ab\u82d7\u4f50\u5242\u3001\u751f\u7269\u50ac\u5316\u5242\u4ee5\u53ca\u5149\u52a8\u529b\/\u5149\u70ed\u6cbb\u7597\u548c\u514d\u75ab\u6cbb\u7597\u7b49\u65b0\u6280\u672f\uff1b\u591a\u5c3a\u5ea6\u5206\u7ea7\u6709\u5e8f\u7ec4\u88c5\u548c\u529f\u80fd\u8c03\u63a7\uff0c\u6784\u5efa\u4eff\u751f\u529f\u80fd\u4f53\u7cfb\u548c\u539f\u7ec6\u80de\uff08protocell\uff09\u6a21\u578b\uff0c\u7814\u7a76\u751f\u5316\u53cd\u5e94\u53ca\u80fd\u91cf\u8f6c\u5316\u673a\u5236<\/strong>\u3002\u5728\u56fd\u9645\u91cd\u8981\u5b66\u672f\u671f\u520aChem. Soc. Rev.\u3001J. Am. Chem. Soc.\u3001Angew. Chem. Int. Ed.\u548cAdv. Mater.\u7b49\u53d1\u8868SCI\u8bba\u6587100\u4f59\u7bc7\uff0c\u4ed6\u5f155000\u4f59\u6b21\u3002\u64b0\u5199\u82f1\u6587\u4e13\u84571\u90e8\uff08Wiley-VCH\u51fa\u7248\u793e\uff09\uff0c\u82f1\u6587\u7ae0\u82825\u7ae0\u3002\u7533\u62a5\u53d1\u660e\u4e13\u522910\u4f59\u9879\u3002\u62c5\u4efb\u56fd\u9645\u671f\u520aColloids and Surfaces A \u526f\u4e3b\u7f16\uff0cChemSystemsChem\u3001Green Energ. Environ.\u3001\u8fc7\u7a0b\u5de5\u7a0b\u5b66\u62a5\u7f16\u59d4\uff0cBiomacromolecules\u3001Chem.-Asian J. \u5ba2\u5ea7\u7f16\u8f91\u3002\u83b7\u4e2d\u56fd\u80f6\u4f53\u4e0e\u754c\u9762\u5316\u5b66\u4f18\u79c0\u9752\u5e74\u6559\u5e08\u5956\u3001\u4e2d\u56fd\u79d1\u5b66\u9662\u4f18\u79c0\u5bfc\u5e08\u5956\u3002<\/p>\n<p><strong>\u8bfe\u9898\u7ec4\u7f51\u7ad9\uff1a<a href=\"http:\/\/www.yan-assembly.org\" target=\"_blank\" rel=\"noopener\">http:\/\/www.yan-assembly.org<\/a><\/strong><\/p>\n<p>\u672c\u6587\u7531\u6750\u6599\u4ebaCQR\u7f16\u8bd1\uff0c\u6750\u6599\u4eba\u6574\u7406\u3002<\/p>\n<p>\u6b22\u8fce\u5927\u5bb6\u5230\u6750\u6599\u4eba\u5ba3\u4f20\u79d1\u6280\u6210\u679c\u5e76\u5bf9\u6587\u732e\u8fdb\u884c\u6df1\u5165\u89e3\u8bfb\uff0c\u6295\u7a3f\u90ae\u7bb1tougao@cailiaoren.com.<\/p>\n<p>\u6295\u7a3f\u4ee5\u53ca\u5185\u5bb9\u5408\u4f5c\u53ef\u52a0\u7f16\u8f91\u5fae\u4fe1\uff1acailiaokefu.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u3010\u80cc\u666f\u4ecb\u7ecd\u3011 \u76ee\u524d\uff0c\u4e34\u5e8a\u4e0a\u6cbb\u7597\u764c\u75c7\u7684\u4e3b\u8981\u65b9\u6cd5\u662f\u624b\u672f\u3001\u653e\u7597\u548c\u5316\u7597\uff0c\u867d\u7136\u5176\u65b9\u6cd5\u5f97\u5230\u5f88\u5927\u6539\u8fdb\uff0c\u4f46\u662f\u5176\u56fa\u6709\u7684\u7f3a\u9677\u4e00\u76f4\u5b58\u5728\u3002\u5982\u4eca\uff0c\u5728\u4f17\u591a\u6cbb\u7597\u764c\u75c7\u7684\u65b0\u65b9\u6cd5\u4e2d\uff0c\u5149\u52a8\u529b\u7597\u6cd5\uff08P&#8230;<\/p>\n","protected":false},"author":7770,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[215,2],"tags":[3602,3931],"class_list":["post-169132","post","type-post","status-publish","format-standard","hentry","category-jiedu","category-keji","tag-ptt","tag-3931"],"_links":{"self":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts\/169132"}],"collection":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/users\/7770"}],"replies":[{"embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=169132"}],"version-history":[{"count":5,"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts\/169132\/revisions"}],"predecessor-version":[{"id":169638,"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts\/169132\/revisions\/169638"}],"wp:attachment":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=169132"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=169132"},{"taxonomy":"post_tag","embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=169132"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}