{"id":166511,"date":"2019-01-31T06:30:32","date_gmt":"2019-01-30T22:30:32","guid":{"rendered":"\/\/m.iemloyee.com\/?p=166511"},"modified":"2019-01-30T18:17:44","modified_gmt":"2019-01-30T10:17:44","slug":"%e3%80%90%e5%b7%b2%e6%a0%a1%e7%a8%bf%e3%80%91-acc-chem-res-%ef%bc%9a%e5%9f%ba%e4%ba%8e%e5%8f%8c%e8%8a%98%e8%87%aa%e7%bb%84%e8%a3%85%e7%ba%b3%e7%b1%b3%e6%9d%90%e6%96%99%ef%bc%9a%e4%bd%93%e5%86%85","status":"publish","type":"post","link":"\/\/m.iemloyee.com\/?p=166511","title":{"rendered":"Acc. Chem. Res.\uff1a\u57fa\u4e8e\u53cc\u8298\u81ea\u7ec4\u88c5\u7eb3\u7c73\u6750\u6599\uff1a\u4f53\u5185\u81ea\u7ec4\u88c5\u3001\u8f6c\u5316\u53ca\u751f\u7269\u533b\u5b66\u6548\u5e94"},"content":{"rendered":"

\u3010\u7814\u7a76\u80cc\u666f\u3011<\/strong><\/p>\n

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\n \u57fa\u4e8eBP\u53ca\u5176\u805a\u96c6\u4f53\u7684\u5149\u7269\u7406\u6027\u8d28\uff0c\u4f5c\u8005\u53c8\u5408\u6210\u4e86\u4e00\u7cfb\u5217\u8bbe\u8ba1\u7684BP\u884d\u751f\u7269\u4f5c\u4e3a\u4f53\u5185\u539f\u4f4d\u6784\u5efa\u751f\u7269\u6210\u50cf\u548c\u6cbb\u7597\u7684\u529f\u80fd\u6027\u7eb3\u7c73\u6750\u6599\u3002\u7136\u540e\u89c2\u5bdf\u5230\u4e86\u51e0\u79cd\u65b0\u7684\u751f\u7269\u533b\u5b66\u6548\u5e94\uff0c\u5982\uff081\uff09\u7ec4\u88c5\/\u805a\u96c6\u8bf1\u5bfc\u7684\u4fdd\u7559\uff08AIR\uff09\u6548\u5e94\uff0c\u8fd9\u79cd\u6548\u5e94\u53cd\u6620\u4e86\u751f\u7269\u6d3b\u6027\u7eb3\u7c73\u6750\u6599\u5728\u76ee\u6807\u533a\u57df\u4e2d\u7684\u79ef\u7d2f\u548c\u4fdd\u7559\uff1b\uff082\uff09\u8f6c\u5316\u8bf1\u5bfc\u7684\u8868\u9762\u7c98\u9644\uff08TISA\uff09\u6548\u5e94\uff0c\u8fd9\u610f\u5473\u7740\u5927\u90e8\u5206BP NPs\u5728\u4e0e\u7279\u5b9a\u53d7\u4f53\u7ed3\u5408\u540e\u8f6c\u5316\u4e3a\u7ec6\u80de\u8868\u9762\u7684\u7eb3\u7c73\u7ea4\u7ef4\uff08NFs\uff09\uff0c\u800c\u901a\u8fc7\u4f20\u7edf\u5185\u541e\u4f5c\u7528\u5165\u80de\u7684BP NPs\u5927\u5927\u51cf\u5c11\uff1b\uff083\uff09\u5c06BP NPs\u8f6c\u5316\u4e3a\u80bf\u7624\u5fae\u73af\u5883\u4e2d\u7684NFs\uff0c\u663e\u793a\u51fa\u9ad8\u79ef\u7d2f\u548c\u957f\u4fdd\u7559\uff0c\u63ed\u793a\u8f6c\u5316\u589e\u5f3a\u7684\u79ef\u7d2f\u548c\u4fdd\u7559\uff08TEAR\uff09\u6548\u5e94\u3002<\/p>\n

\u3010\u6210\u679c\u7b80\u4ecb\u3011<\/strong><\/p>\n

\u5728\u672c\u8bba\u6587\u4e2d\uff0c\u56fd\u5bb6\u7eb3\u7c73\u4e2d\u5fc3\u738b\u6d69\u7814\u7a76\u5458\u3001\u738b\u78ca\u7814\u7a76\u5458\u548c\u4e2d\u5357\u6c11\u65cf\u5927\u5b66\u674e\u9999\u4e39\u6559\u6388<\/strong>\u603b\u7ed3\u4e86BP\u5355\u5143\u5728\u751f\u7269\u73af\u5883\u4e2d\u805a\u96c6\u65f6\u7684\u8367\u5149\u7279\u6027\u548c\u53d1\u5c04\u673a\u5236\u3002\u6b64\u5916\uff0c\u4f5c\u8005\u4ecb\u7ecd\u4e86\u7528\u4e8e\u4f53\u5185\u81ea\u7ec4\u88c5\u548c\u8f6c\u5316\u7684BP\u884d\u751f\u5316\u5408\u7269\uff0c\u6d89\u53ca\u8c03\u8282\u7b56\u7565\u3002\u968f\u540e\u53c8\u8ba8\u8bba\u4e86\u57fa\u4e8eBP\u7684\u7eb3\u7c73\u6750\u6599\u51fa\u4e4e\u610f\u6599\u7684\u751f\u7269\u533b\u5b66\u6548\u5e94\u548c\u6cbb\u7597\u8bca\u65ad\u7684\u5e94\u7528\u3002\u6700\u540e\uff0c\u4f5c\u8005\u8fd8\u603b\u7ed3\u4e86\u57fa\u4e8eBP\u7684\u81ea\u7ec4\u88c5\u7eb3\u7c73\u6750\u6599\u7684\u672a\u6765\u53d1\u5c55\u524d\u666f\u3002\u8be5\u6210\u679c\u8fd1\u65e5\u4ee5\u9898\u4e3a\u201cBispyrene-Based Self-Assembled Nanomaterials: In Vivo Self-Assembly, Transformation, and Biomedical Effects<\/strong>\u201d\u53d1\u8868\u5728\u77e5\u540d\u671f\u520aAcc. Chem. Res.<\/strong>\u4e0a\u3002<\/p>\n

\u3010\u56fe\u6587\u5bfc\u8bfb\u3011<\/strong><\/p>\n

\u57fa\u4e8e\u53cc\u8298\u7684\u539f\u4f4d\u81ea\u7ec4\u88c5\u548c\u8f6c\u5316\u7528\u4e8e\u764c\u75c7\u8bca\u65ad\u548c\u6cbb\u7597\u7684\u793a\u610f\u56fe<\/strong>
\n \"\"
\n \u56fe\u4e00\uff1a\u53cc\u8298\u5206\u5b50\u7ed3\u6784\u3001\u8367\u5149\u7279\u6027\u53ca\u81ea\u7ec4\u88c5\u6027\u8d28<\/strong>
\n \"\"
\n \uff08a\uff09BP\u7684\u5206\u5b50\u7ed3\u6784\uff1b
\n \uff08b\uff09\u5355\u4f53BP\u7684\u7b2c\u4e00\u6fc0\u53d1\u6001\u4e2d\u7684LUMO\u548cHOMO\u7684\u7b49\u503c\u7ebf\u56fe\uff1b
\n \uff08c\uff09\u901a\u8fc7XRD\u6d4b\u91cfBP\u5206\u5b50\u5806\u79ef\uff1b
\n \uff08d\uff09\u81ea\u7ec4\u88c5BP\u7eb3\u7c73\u9897\u7c92\u7684TEM\u56fe\u50cf\uff1b
\n \uff08e\uff09\u5728DMSO\/H2O\u6df7\u5408\u6eb6\u6db2\u4e2dBP\u7684\u8367\u5149\u5149\u8c31\uff0c\u63d2\u56fe\u4e3a365nm\u7d2b\u5916\u5149\u6fc0\u53d1\u4e0bBP\u7eb3\u7c73\u9897\u7c92\u7684\u53d1\u5c04\u56fe\u50cf\uff1b
\n \uff08f\uff09BP\u57281600 \u03bcm\u6a21\u62df\u7ec4\u7ec7\u4e0a\u7684\u53cc\u5149\u5b50\u8367\u5149\uff1b
\n \uff08g\uff09BP-\u5171\u8f6d\u82b1\u9752\u67d3\u6599\uff08BP-Cy\uff09\u81ea\u7ec4\u88c5\u6210\u7eb3\u7c73\u56ca\u6ce1\u7684\u793a\u610f\u56fe\uff1b
\n \uff08h\uff09BP-Cy\u7eb3\u7c73\u56ca\u6ce1\u7684TEM\u56fe\u50cf\u3002<\/p>\n

\u56fe\u4e8c\uff1a\u4f53\u5185\u5916\u539f\u4f4d\u81ea\u7ec4\u88c5\u53ca\u6210\u50cf<\/strong>
\n \"\"
\n \uff08a\uff09BP\u5206\u6563\u7684\u80f6\u675f\uff1b
\n \uff08b\uff09BP\u4ece\u80f6\u675f\u4e2d\u91ca\u653e\u53caBP\u5728\u6eb6\u9176\u4f53\u4e2d\u7684\u805a\u96c6\u7684\u793a\u610f\u56fe\uff1b
\n \uff08c\uff09\u5728365nm\u4e0b\u4e0d\u540cpH\u4e0bBP\u5206\u6563\u7684PbAE\u80f6\u675f\u7684\u8367\u5149\u5149\u8c31\u548c\u56fe\u50cf\uff1b\uff08d\uff09\u4ee5\u4e0d\u540c\u65f6\u95f4\u95f4\u9694\u4e0eHeLa\u7ec6\u80de\u4e00\u8d77\u5b75\u80b2\u7684PbAE\u80f6\u675f\u7684\u65cb\u8f6c\u76d8\u5171\u805a\u7126\u663e\u5fae\u955c\uff08SDCM\uff09\u56fe\u50cf\uff1b
\n \uff08e\uff09\u5728\u6d3b\u7ec6\u80de\u4e2d\u7528\u4e8e\u81ea\u566c\u68c0\u6d4b\u7684DP-BP\u7684\u5206\u5b50\u7ed3\u6784\uff1b
\n \uff08f\uff09DP-BP\u539f\u4f4d\u81ea\u7ec4\u88c5\u673a\u5236\u7684\u793a\u610f\u56fe\uff1b
\n \uff08g\uff09DP-BP\u7ed3\u6784\u8f6c\u5316\u7684TEM\u56fe\u50cf\uff1b
\n \uff08h\uff09\u53d7\u7cbe\u540e2\u5929\u7684\u6591\u9a6c\u9c7c\u80da\u80ce\u7528PBS\u6216Rapa\u5904\u740624\u5c0f\u65f6\uff0c\u7136\u540e\u7528DP-BP\u67d3\u82724\u5c0f\u65f6\u7684CLSM\u56fe\u50cf\u3002<\/p>\n

\u56fe\u4e09\uff1a\u70ed\u54cd\u5e94\u805a\u5408\u7269\u8c03\u63a7\u7684BP\u81ea\u7ec4\u88c5\u53ca\u5e94\u7528<\/strong>
\n \"\"
\n \uff08a\uff09\u7528\u4e8e\u76d1\u6d4b\u548c\u64cd\u7eb5HER2\u53d7\u4f53\u805a\u96c6\u7684\u7ec6\u80de\u8868\u9762\u4e0aBP\u81ea\u7ec4\u88c5\u7684\u70ed\u63a7\u5236\u7684\u793a\u610f\u56fe\uff1b
\n \uff08b\uff09\u542b\u6709BP\u7684PNIPAAm\u7684\u5206\u5b50\u7ed3\u6784\uff1b
\n \uff08c\uff09\u6d4a\u5ea6\u8bd5\u9a8c\uff1b
\n \uff08d\uff09\u5728\u4e0d\u540c\u6e29\u5ea6\u4e0bPNIPAAm\u7684PBS\u6eb6\u6db2\u7684\u8367\u5149\u53d8\u5316\uff1b
\n \uff08e\uff0940\u548c35\u2103\u4e0bSK-BR-3\u7ec6\u80de\u4e0aBP\u5f62\u6001\u53d8\u5316\u7684CLSM\u56fe\u50cf\u3002<\/p>\n

\u56fe\u56db\uff1a\u805a\u5408\u7269\u8f85\u52a9\u89e3\u7ec4\u88c5<\/strong>
\n \"\"
\n \uff08a\uff09P-BP\u7684\u5206\u5b50\u7ed3\u6784\u548c\u81ea\u7ec4\u88c5\u7684P-BP NPs\u7684\u793a\u610f\u56fe\uff1b
\n \uff08b\uff09P-BP\/NR\u5728\u4f4epH\u4e0b\u5177\u6709\u589e\u5f3a\u7684\u8367\u5149\u7684\u6eb6\u80c0\u793a\u610f\u56fe\uff1b
\n \uff08c\uff09P-BP\/NR\u5728\u5404\u79cdpH\u6761\u4ef6\u4e0b\u7684F418\/F635\uff1b
\n \uff08d\uff09\u7528P-BP\/NR\u5b75\u80b2\u4e0d\u540c\u65f6\u95f4\u7684U87\u7ec6\u80de\u7684CLSM\u56fe\u50cf\u3002<\/p>\n

\u56fe\u4e94\uff1a\u53cc\u53d1\u5c04\u7eb3\u7c73\u8367\u5149\u63a2\u9488\u7684\u5236\u5907\u3001\u6027\u8d28\u53ca\u6d3b\u4f53\u6210\u50cf\u5e94\u7528<\/strong>
\n \"\"
\n \uff08a\uff09\u57fa\u4e8eGSH\u7684\u751f\u7269\u6b63\u4ea4\u53cd\u5e94\u7684\u5316\u5b66\u7ed3\u6784\u548c\u793a\u610f\u56fe\uff1b
\n \uff08b\uff0cc\uff09\u5728820nm\u548c520nm\u7684\u7eb3\u7c73\u8367\u5149\u63a2\u9488\u968fGSH\u6d53\u5ea6\u589e\u52a0\u7684\u8367\u5149\u5149\u8c31\uff1b
\n \uff08d\uff09\u6ce8\u5c04PBS\u548c\u7eb3\u7c73\u8367\u5149\u63a2\u9488\u540e12\u5c0f\u65f6\u7684\u79bb\u4f53\u7ec4\u7ec7\u548c\u80bf\u7624\u7684\u8367\u5149\u56fe\u50cf\u3002<\/p>\n

\u56fe\u516d\uff1a\u4eb2\u758f\u6c34\u4f5c\u7528\u8bf1\u5bfc\u7684\u4eceNPs\u5230NFs\u7684\u5f62\u6001\u8f6c\u5316<\/strong>
\n \"\"
\n \uff08a\uff09BP-KP\u4ece\u5355\u4f53\u5230NPs\u5230NFs\u7684\u5f62\u6001\u8f6c\u5316\u7684\u793a\u610f\u56fe\uff1b
\n \uff08b\uff09BP-KP\u7684\u5206\u5b50\u7ed3\u6784\uff1b
\n \uff08c\uff09BP-KP2\u548cBP-KP3\u7ed3\u6784\u968f\u65f6\u95f4\u53d8\u5316\u7684TEM\u56fe\u50cf\u3002<\/p>\n

\u56fe\u4e03\uff1a\u914d\u4f53\u2212\u53d7\u4f53\u76f8\u4e92\u4f5c\u7528\u8bf1\u5bfc\u5f62\u6001\u8f6c\u53d8<\/strong>
\n \"\"
\n \uff08a\uff09\u901a\u8fc7\u914d\u4f53-\u53d7\u4f53\u4f5c\u7528\u5c06BP-KR\u4eceNPs\u8f6c\u5316\u4e3aNFs\u7684\u793a\u610f\u56fe\uff1b
\n \uff08b\uff09BP-KR\u7684\u5206\u5b50\u7ed3\u6784\uff1b
\n \uff08c\uff094\u5929\u540e\u901a\u8fc7TEM\u89c2\u5bdf\u6709\/\u65e0Ca2+\u6761\u4ef6\u4e0bBP-KR\u7684\u7ed3\u6784\u8f6c\u5316\uff1b
\n \uff08d\uff09\u6c34\u6eb6\u6db2\u4e2d\u6709\/\u65e0\u91d1\u5c5e\u79bb\u5b50\u65f6BP-KR\u7684\u8367\u5149\u5149\u8c31\uff1b
\n \uff08e\uff09SEM\u89c2\u5bdf\u5728U87\u7ec6\u80de\u8868\u9762BP-KR\u4eceNPs\u5230NFs\u7684\u5f62\u6001\u8f6c\u5316\u3002<\/p>\n

\u56fe\u516b\uff1a\u5f62\u6001\u8f6c\u53d8\u6291\u5236\u80bf\u7624\u8f6c\u79fb<\/strong>
\n \"\"
\n \uff08a\uff09BP-KRY NPs\u8f6c\u5316\u4e3aBP-KRY NFs\u6784\u5efa\u4eba\u5de5\u7ec6\u80de\u5916\u57fa\u8d28\u4ee5\u6291\u5236\u80bf\u7624\u8f6c\u79fb\u7684\u793a\u610f\u56fe\uff1b
\n \uff08b\uff09\u5728\u6c34\u6eb6\u6db2\u4e2dCa2+\u5b58\u5728\u4e0bBP-KRY NPs\u7684\u5f62\u6001\u8f6c\u5316TEM\u56fe\u50cf\uff1b
\n \uff08c\uff09BP-KRY NPs\u5728\u7ec6\u80de\u8868\u9762\u4e0a\u7684\u7ed3\u6784\u8f6c\u5316\u7684SEM\u56fe\u50cf\uff1b
\n \uff08d\uff09BP-KRY NPs\u5728\u79bb\u4f53\u7ec4\u7ec7\u548c\u80bf\u7624\u4e2d\u7684\u751f\u7269\u5206\u5e03\u3002<\/p>\n

\u56fe\u4e5d\uff1a\u5f62\u6001\u8f6c\u53d8\u4e0b\u7684\u4e24\u6b65\u7ed9\u836f\u7b56\u7565<\/strong>
\n \"\"
\n \uff08a\uff09pH\u5f15\u53d1\u7684BP-KPH\u4eceNPs\u5230NFs\u7684\u7ed3\u6784\u8f6c\u5316\u7684\u793a\u610f\u56fe\uff1b
\n \uff08b\uff09BP-KPH\u7684\u5206\u5b50\u7ed3\u6784\uff1b
\n \u5728\u4e0d\u540cpH\u4e0b\u4eceNPs\uff08c\uff09\u5230NFs\uff08d\uff09\u7684\u5f62\u6001\u8f6c\u5316\u7684TEM\u56fe\u50cf\uff1b
\n \uff08e\uff09BP-KPH NFs\u6eb6\u6db2\u7684\u7167\u7247\uff0c\u5728365nm\u7d2b\u5916\u706f\u4e0bNR\u4ece0\u52302\u03bcM\u9010\u6e10\u589e\u52a0\uff1b
\n \uff08f\uff09\u80bf\u7624\u5207\u7247\u4e2dBP-KPH NPs\u7684\u5f62\u6001\u8f6c\u5316\u7684\u751f\u7269TEM\u56fe\u50cf\uff1b
\n \uff08g\uff09CLSM\u56fe\u50cf\u89c2\u5bdf\u80bf\u7624\u7ec4\u7ec7\u4e2dBP-KPH\/NR NFs\u548cC-BP-KPH\/NR NPs\u7684FRET\u4fe1\u53f7\uff1b
\n \uff08h\uff09\u6709\/\u65e0BP-KPH NFs\u7684MCF-7\u8377\u7624\u5c0f\u9f20\u7684\u70ed\u56fe\u50cf\uff1b
\n \uff08i\uff09\u5728\u4e0d\u540c\u5149\u70ed\u5904\u7406\u4e0bMCF-7\u8377\u7624\u5c0f\u9f20\u7684\u76f8\u5bf9\u80bf\u7624\u4f53\u79ef\u968f\u65f6\u95f4\u53d8\u5316\u3002<\/p>\n

\u3010\u5c0f\u7ed3\u3011<\/strong><\/p>\n

\u81ea\u7ec4\u88c5\u7eb3\u7c73\u6750\u6599\u73b0\u5df2\u5e7f\u6cdb\u7528\u4e8e\u7eb3\u7c73\u533b\u5b66\u9886\u57df\u3002\u4f46\u7531\u4e8e\u81ea\u7ec4\u88c5\u7eb3\u7c73\u6750\u6599\u7684\u52a8\u6001\u6027\u8d28\uff0c\u5f53\u5728\u4f53\u5185\u63a5\u89e6\u751f\u7269\u754c\u9762\u65f6\uff0c\u5176\u5f62\u6001\u548c\u6027\u8d28\u90fd\u4f1a\u53d1\u751f\u53d8\u5316\u3002\u4e3a\u4e86\u6df1\u5165\u4e86\u89e3\u7eb3\u7c73\u7ec4\u88c5\u6750\u6599\u5728\u4f53\u5185\u53d1\u751f\u7684\u60c5\u51b5\uff0c\u4f5c\u8005\u63d0\u51fa\u4e86\u4e00\u79cd\u4f53\u5185\u81ea\u7ec4\u88c5\u7b56\u7565\uff0c\u4ee5\u89c2\u5bdf\u4f53\u5185\u81ea\u7ec4\u88c5\u8fc7\u7a0b\u5e76\u539f\u4f4d\u6784\u5efa\u81ea\u7ec4\u88c5\u7eb3\u7c73\u6750\u6599\u3002\u56e0\u6b64BP\u5206\u5b50\u5355\u5143\u5e94\u8fd0\u800c\u751f\uff0c\u5176\u5728\u7ec4\u88c5\u65f6\u663e\u793a\u51fa\u589e\u5f3a\u7684\u8367\u5149\uff0c\u5e76\u4e14\u7531\u4e8e\u8298\u7684\u5f3a\u758f\u6c34\u6027\u548c\u03c0-\u03c0\u76f8\u4e92\u4f5c\u7528\u800c\u503e\u5411\u4e8e\u8bf1\u5bfc\u81ea\u7ec4\u88c5\u3002\u6b64\u5916\uff0cBP NPs\u5728\u4e0eKLVFF\u5076\u8054\u65f6\u8f6c\u5316\u4e3aNFs\u3002\u539f\u4f4d\u81ea\u7ec4\u88c5\u901a\u5e38\u5728\u7279\u5b9a\u751f\u7406\u548c\u75c5\u7406\u533a\u57df\u7684\u523a\u6fc0\u4e0b\u5b9e\u73b0\uff0c\u5982\u9176\u3001pH\u548c\u6c27\u5316\u8fd8\u539f\u5e94\u6fc0\uff0c\u7528\u4e8e\u6784\u5efa\u529f\u80fd\u6027\u6cbb\u7597\u8bca\u65ad\u7eb3\u7c73\u7c92\u5b50\u7528\u4e8e\u63d0\u9ad8\u8840\u6db2\u5faa\u73af\uff0c\u9776\u5411\uff0c\u79ef\u7d2f\uff0c\u4fdd\u7559\u548c\u91ca\u653e\u3002\u539f\u4f4d\u81ea\u7ec4\u88c5\u53ef\u4ee5\u667a\u80fd\u5730\u76d1\u6d4b\u751f\u7269\u8fc7\u7a0b\uff0c\u751f\u7269\u5206\u5b50\u7684\u6d3b\u6027\u4ee5\u53ca\u8fdb\u884c\u4f53\u5185\u75be\u75c5\u8bca\u65ad\u3002\u6784\u5efa\u7eb3\u7c73\u6750\u6599\u7684\u539f\u4f4d\u8f6c\u5316\u663e\u793a\u51fa\u65b0\u7684\u751f\u7269\u533b\u5b66\u6548\u5e94\uff0c\u4f8b\u5982\u4e0e\u7ec6\u80de\u6444\u53d6\u4e0d\u540c\u7684\u8f6c\u5316\u8bf1\u5bfc\u7684\u8868\u9762\u7c98\u9644\uff08TISA\uff09\u6548\u5e94\uff0c\u663e\u793a\u51fa\u6bd4\u4f20\u7edfNPs\u7684EPR\u6548\u5e94\u66f4\u957f\u4fdd\u7559\u7684\u8f6c\u5316\u589e\u5f3a\u7684\u79ef\u7d2f\u548c\u4fdd\u7559\uff08TEAR\uff09\u6548\u5e94\u7b49\u3002\u57fa\u4e8e\u53cc\u8298\u81ea\u7ec4\u88c5\u7eb3\u7c73\u6750\u6599\u9664\u4e86\u4eceNPs\u5230NFs\u7684\u5f62\u6001\u8f6c\u6362\u5916\uff0c\u6839\u636e\u751f\u7269\u533b\u5b66\u6210\u50cf\u548c\u6cbb\u7597\u7684\u9700\u8981\uff0c\u53ef\u4ee5\u8fdb\u884c\u5305\u62ec\u5c3a\u5bf8\u3001\u8868\u9762\u7535\u8377\u548c\u5f62\u72b6\u8c03\u63a7\uff0c\u663e\u793a\u51fa\u6781\u5177\u524d\u9014\u7684\u667a\u80fd\u6027\u548c\u9488\u5bf9\u6027\u3002
\n \u76ee\u524d\uff0c\u8fd9\u4e2a\u9886\u57df\u4e5f\u51fa\u73b0\u4e86\u4e00\u4e9b\u65b0\u7684\u6311\u6218\uff0c\u4e3b\u8981\u5185\u5bb9\u5982\u4e0b\uff1a
\n \uff08i\uff09\u5b9e\u73b0\u751f\u7269\u9002\u5e94\u6027\u81ea\u7ec4\u88c5\u7684\u524d\u4f53\u7684\u8bbe\u8ba1\u539f\u5219\uff0c\u5e76\u7cbe\u786e\u63a7\u5236\u4f53\u5185\u4ea7\u751f\u7684\u76ee\u6807\u7ed3\u6784\uff1b
\n \uff08ii\uff09\u5f00\u53d1\u5148\u8fdb\u7684\u4f53\u5185\u5de5\u5177\u548c\u8868\u5f81\u81ea\u7ec4\u88c5\u7ed3\u6784\u52a8\u6001\u884c\u4e3a\u7684\u7b56\u7565\uff1b
\n \uff08iii\uff09\u7406\u89e3\u751f\u7269\u754c\u9762\u4e2d\u5916\u6e90\u81ea\u7ec4\u88c5\u6750\u6599\u7684\u7ed3\u6784\u6f14\u53d8\uff1b
\n \uff08iv\uff09\u5728\u4f53\u5185\u81ea\u7ec4\u88c5\u7eb3\u7c73\u6750\u6599\u7684\u5206\u89e3\u548c\u6392\u6cc4\u7684\u5f62\u6001\u548c\u7ed3\u6784\u8f6c\u53d8\u5e94\u5f15\u8d77\u5e7f\u6cdb\u5173\u6ce8\u3002
\n \u6700\u540e\uff0c\u4f5c\u8005\u8ba4\u4e3a\u5bf9\u81ea\u7ec4\u88c5\u7eb3\u7c73\u6750\u6599\u7684\u529f\u6548\u548c\u751f\u7269\u5b89\u5168\u6027\u7684\u7cfb\u7edf\u8bc4\u4f30\u5c06\u6781\u5927\u5730\u5e2e\u52a9\u5176\u4e34\u5e8a\u667a\u6cbb\u7597\u8bca\u65ad\u5e94\u7528\u7684\u8f6c\u5316\u3002<\/p>\n

\u6587\u732e\u94fe\u63a5\uff1aBispyrene-Based Self-Assembled Nanomaterials: In Vivo Self-Assembly, Transformation, and Biomedical Effects<\/a> (Acc. Chem. Res.<\/em>, 2019<\/strong>, DOI: 10.1021\/acs.accounts.8b00398)<\/p>\n

\u5173\u4e8eBP\u5206\u5b50\u7684\u76f8\u5173\u6587\u732e\uff1a<\/strong>
\n 1. Hongqian Cao, Yanfei Qi, Yang Yang,* Lei Wang, Jiaheng Sun, Yue Li, Jiarui Xia, Hao Wang and Junbai Li*, Assembled Nanocomplex for Improving Photodynamic Therapy through Intraparticle Fluorescence Resonance Energy Transfer, Chem. Asian J., 2018, 13(22), 3540-3546.
\n 2. Pei-Pei Yang, Chao Yang, Kuo Zhang, Lei Wang,* and Hao Wang* KLVFF Peptide Functionalized Nanoparticles Capture A\u03b242 by Co-Assembly for Decreasing Cytotoxicity, 2018 In press.
\n 3. Bing-Nan Li, Ping-Ping He, Pei-Pei Yang, Jing-Ping Zhang,* Lei Wang* and Hao Wang*, In situ construction of nano-networks from transformable nanoparticles for anti-angiogenic therapy, J. Mater. Chem. B, J. Mater. Chem. B, 2018, 6, 5282-5289.
\n 4. Qiang Luo,# Yao-Xin Lin,# Pei-Pei Yang,# Yi Wang, Guo-Bin Qi, Zeng-Ying Qiao, Bing-Nan Li, Kuo Zhang, Jing-Ping Zhang,* Lei Wang* and Hao Wang*, A Self-destructive Nanosweeper that Captures and Clears Amyloid \u03b2-Peptides, Nature Commun., 2018, 9, 1802. \u8bb2\u5de5\u4f5c
\n 5. Guo-Bin Qi, Yu-Juan Gao, Lei Wang* and Hao Wang*, Self-Assembled Peptide-Based Nanomaterials for Biomedical Imaging and Therapy, Adv. Mater., 2018, 30(22), 1703444.
\n 6. Hongqian Cao, Lei Wang, Yang Yang,* Juan Li, Yanfei Qi, Yue Li, Ying Li, Hao Wang and Junbai Li*, An Assembled Nano-complex for Improving both Therapeutic Efficiency and Treatment Depth in Photodynamic Therapy, Angew. Chem., Int. Ed. 2018, 57(26), 7759-7763.
\n 7. Yao-Xin Lin,# Xue-Feng Hu,# Yang Zhao, # Yu-Juan Gao, Chao Yang, Sheng-Lin Qiao, Jiao Yan, Pei-Pei Yang, Qian Zeng, Zeng-Ying Qiao, Li-Li Li, Jiang-Bing Xie, Si-Quan Zhu, Xiao-Chun Wu, Lei Wang* and Hao Wang*, Intraocular Lens with Amorphous Nanostructured Rim for High-Efficient Eye-Disease Treatment, Adv. Mater., 2017, 29(34), 1701617.
\n 8. Pei-Pei Yang,# Qiang Luo,# Guo-Bin Qi,# Yu-Juan Gao, Bing-Nan Li, Jing-Ping Zhang, Lei Wang* and Hao Wang*, Host Materials Transformable in Tumor Microenvironment for Homing Theranostics, Adv. Mater., 2017, 29(15), 1605869.
\n 9. Yao-Xin Lin, Sheng-Lin Qiao, Yi Wang, Ruo-Xin Zhang, Hong-Wei An, Zeng-Ying Qiao, Lei Wang* and Hao Wang*, An in situ Intracellular Self-Assembly Strategy for Quantitative and Temporal Monitoring Autophagy, ACS Nano, 2017, 11(2), 1826-1839.
\n 10. Xiao-Xue Hu, Guo-Bin Qi, Yu-Juan Gao, Yao-Xin Lin, Chao Yang, Pei-Pei Yang, Hong-Xun Hao*, Lei Wang* and Hao Wang*, Artificial Extracellular Matrix Based on Transformable Nanomaterials for High-Efficient Inhibition of Tumor Invasion and Metastasis, ACS Nano, 2017, 11(4), 4086-4096.
\n 11. Bingbing Sun, Lei Wang, Qi Li, Pingping He, Huiling Liu, Hao Wang, Yang Yang,* Junbai Li*, Bis(pyrene) Doped Cationic Dipeptide Nanoparticles for Two-Photon-Activated Photodynamic Therapy, Biomacromolecules, 2017, 18(11), 3506-3513.
\n 12. Hong-Wei An, Sheng-Lin Qiao, Li-Li Li, Chao Yang, Yao-Xin Lin, Yi Wang, Zeng-Ying Qiao, Lei Wang* and Hao Wang*, Bioorthogonal Reaction Drives Selective Segmentation of Components from Nanoaggregates for Specific Intracellular Bioimaging, ACS Appl. Mater. Interfaces, 2016, 8 (30), 19202\u201319207.
\n 13. An-Ping Xu,# Pei-Pei Yang,# Chao Yang, Yu-Juan Gao, Xiao-Xiao Zhao, Qiang Luo, Li-Zhong Li,* Lei Wang* and Hao Wang*, Bio-Inspired Metal Ions Regulate Morphological Transformation of Self-Assembled Peptide-Based Nanoparticles, Nanoscale, 2016, 8, 14078\u201314083.
\n 14. Pei-Pei Yang,# Yun-Gang Zhai,# Yao-Xin Lin, Xiao-Xiao Zhao, Yu-Juan Gao, Yang Yang, An-Ping Xu, Chao Yang, Yong-Sheng Li,* Lei Wang* and Hao Wang*, Janus Nanoparticles with Active Motion by NIR Light Propulsion for High Efficient Enhanced Photothermal Treatment, Small, 2016, 12(39), 5423\u20135430.
\n 15. Sheng-Lin Qiao, Yi Wang, Yao-Xin Lin, Hong-Wei An, Li-Li Li, Lei Wang* and Hao Wang*, Thermo-Control Over Self-Assembly of Polymeric Bis(pyrene)s on Cell Surfaces for Monitoring and Regulating Receptor Clustering, ACS Appl. Mater. Interfaces, 2016, 8(27), 17016\u201317022.
\n 16. Pei-Pei Yang, Xiao-Xiao Zhao, An-Ping Xu, Lei Wang* and Hao Wang*, Reorganization of Self-Assembled Polymeric Peptides Controlled by Hydrogen Bonding and Hydrophilic\/Hydrophobic Balance, J. Mater. Chem. B, 2016, 4, 2662\u20132668.
\n 17. Hong-Wei An, Sheng-Lin Qiao, Chun-Yuan Hou, Yao-Xin Lin, Lei Wang* and Hao Wang* Self-Assembled NIR Nanovesicles for Long-Term Photoacoustic Imaging In Vivo, Chem. Commun., 51, 13488\u201313491.
\n 18. Zeng-Ying Qiao, Chun-Yuan Hou, Wen-Jing Zhao, Di Zhang, Pei-Pei Yang, Lei Wang* and Hao Wang*, Synthesis of Self-Reporting Polymeric Nanoparticles for In Situ Monitoring Endocytic Microenvironmental pH, Chem. Commun., 51, 12609\u201312612.
\n 19. Zhongyu Duan,* Yu-Juan Gao, Zeng-Ying Qiao, Shenglin Qiao, Yongmei Wang, Chunyuan Hou, Lei Wang* and Hao Wang*, pH-Sensitive polymer assisted self-aggregation of bis(pyrene) in living cells in situ with turn-on fluorescence., Nanotechnology, 2015, 26, 355703.
\n 20. Pei-Pei Yang, Yang Yang, Yu-Juan Gao, Yi Wang, Ju-Chen Zhang, Yao-Xin Lin, Luru Dai, Junbai Li, Lei Wang* and Hao Wang*, Unprecedentedly High Tissue Penetration Capability of Co-Assembled Nanosystems for Two-Photon Fluorescence Imaging In Vivo, Adv. Optical. Mater., 2015, 3(5), 646\u2013651.
\n 21. Wei Li, Pei-Pei Yang, Lei Wang* and Hao Wang*, Bis-Pyrene Based Reversibly Multi-Responsive Fluorescence Switches, J. Mater. Chem. C. 2015, 3, 3783\u20133789.
\n 22. Lei Wang, Wei Li, Jing Lu, Jing-Ping Zhang* and Hao Wang* Bis-Pyrene Carbocations for Chromogenic and Fluorogenic Dual Detection of Fluoride Anion In Situ, Tetrahedron, 2014, 70(19), 3172\u20133177.
\n 23. Wei Li,# Lei Wang,# Jing-Ping Zhang* and Hao Wang*, Bis-Pyrene-Based Supramolecular Aggregates with Reversibly Mechanochromic and Vaporchromic Responsiveness, J. Mater. Chem. C, 2014, 2(10), 1887\u20131892.
\n 24. Lei Wang, Li-li Li, Yun-shan Fan and Hao Wang*, Host\u2013Guest Supramolecular Nanosystems for Cancer Diagnostics and Therapeutics, Adv. Mater., 2013, 25(28), 3888\u20133898.
\n 25. Lei Wang, Wei Li, Jing Lu, Ying-Xi Zhao, Gang Fan, Jing-Ping Zhang* and Hao Wang*, Supramolecular Nano-Aggregates Based on Bis(Pyrene) Derivatives for Lysosome-Targeted Cell Imaging, J. Phys. Chem. C, 2013, 117(50), 26811\u201326820.<\/p>\n

\u901a\u8baf\u4f5c\u8005\u7b80\u4ecb\uff1a<\/strong><\/p>\n

\u738b\u6d69\u7814\u7a76\u5458<\/strong>\uff0c\u56fd\u5bb6\u7eb3\u7c73\u79d1\u5b66\u4e2d\u5fc3\u7814\u7a76\u5458\uff0c\u535a\u58eb\u751f\u5bfc\u5e08\uff0c\u4e2d\u56fd\u79d1\u5b66\u9662\u201c\u767e\u4eba\u8ba1\u5212\u201d\u5f15\u8fdb\u6d77\u5916\u6770\u51fa\u4eba\u624d\uff0c\u56fd\u5bb6\u6770\u51fa\u9752\u5e74\u79d1\u5b66\u57fa\u91d1\u83b7\u5f97\u8005\u3002
\n 2005\u5e74\u5728\u5357\u5f00\u5927\u5b66\u83b7\u5f97\u7406\u5b66\u535a\u58eb\u5b66\u4f4d\u3002 2006\u5e74\u83b7\u5f97\u6d2a\u5821\u5956\u5b66\u91d1\uff0c2007\u5e74\u83b7\u5f97\u5168\u56fd\u4f18\u79c0\u767e\u7bc7\u535a\u58eb\u6bd5\u4e1a\u8bba\u6587\u63d0\u540d\u5956\uff0c\u5e76\u83b7\u5f97\u5929\u6d25\u5e02\u4f18\u79c0\u535a\u58eb\u6bd5\u4e1a\u8bba\u6587\u3002\u8fd15\u5e74\u6765\uff0c\u7814\u7a76\u4e3b\u8981\u96c6\u4e2d\u5728\u751f\u7269\u533b\u7528\u7eb3\u7c73\u6750\u6599\u7684\u5236\u5907\u53ca\u5176\u5728\u4f53\u5185\u5f71\u50cf\u5b66\u65b9\u9762\u7684\u5e94\u7528\u3002\u738b\u6d69\u7814\u7a76\u5458\u4ee5\u4e3b\u8981\u4f5c\u8005\u5148\u540e\u5728\u56fd\u9645\u8457\u540d\u5b66\u672f\u520a\u7269\u5982 Nat. Commun., Angew. Chem. Int. Ed., J. Am. Chem. Soc.\u7b49\u6742\u5fd7\u4e0a\u53d1\u8868\u8bba\u6587100\u4f59\u7bc7\uff0c\u53c2\u7f16\u4e13\u84574\u90e8\u3002 2010\u5e74\u53d1\u8868\u7684\u5173\u4e8e\u81ea\u52a8\u5316\u751f\u4ea7\u7eb3\u7c73\u57fa\u56e0\u9012\u9001\u8f66\u7684\u6587\u7ae0\u88ab\u300a\u79d1\u6280\u65e5\u62a5\u300b\u5728\u56fd\u9645\u65b0\u95fb\u7248\u5934\u6761\u62a5\u9053\u3002\u7533\u8bf7\u5e76\u83b7\u516c\u5f00\u56fd\u9645\u4e13\u52292\u9879\uff0c\u56fd\u5185\u4e13\u522914\u9879\uff0c\u5176\u4e2d\u4e00\u9879\u4e13\u5229\u5df2\u7ecf\u8fdb\u5165\u4e34\u5e8a\u8bd5\u9a8c\u3002\u4f5c\u4e3a\u9879\u76ee\u8d1f\u8d23\u4eba\u627f\u62c5\u4e86\u79d1\u6280\u90e8973\uff08\u7eb3\u7c73\u91cd\u5927\u7814\u7a76\u8ba1\u5212\uff09\u57fa\u91d1\uff0c\u56fd\u5bb6\u6770\u51fa\u9752\u5e74\u79d1\u5b66\u57fa\u91d1\uff0c\u4e2d\u79d1\u9662\u767e\u4eba\u8ba1\u5212\uff0c\u56fd\u5bb6\u57fa\u91d1\u59d4\u9762\u4e0a\u9879\u76ee\uff0c\u5317\u4eac\u5e02\u81ea\u7136\u79d1\u5b66\u57fa\u91d1\uff0c\u5317\u4eac\u5e02\u751f\u547d\u79d1\u5b66\u9886\u57df\u524d\u6cbf\u6280\u672f\u57f9\u80b2\u4e13\u9879\uff0c\u4e2d\u56fd\u79d1\u5b66\u9662\u4ea4\u53c9\u56e2\u961f\u9879\u76ee\uff0c\u4e2d\u56fd\u79d1\u5b66\u9662\u56fd\u9645\u5408\u4f5c\u5c40\u5bf9\u5916\u5408\u4f5c\u91cd\u70b9\u9879\u76ee\u7b49\u79d1\u7814\u9879\u76ee\u3002
\n \u4ee3\u8868\u6027\u8bba\u6587\uff08*\u4e3a\u901a\u8baf\u4f5c\u8005\uff09
\n 1. Li-Li Li\u2020, Sheng-Lin Qiao\u2020, Wei-Jiao Liu, Yang Ma, Dong Wan, Jie Pan, Hao Wang*,Intracellular Construction of Topology-Controlled Polypeptide Nanostructures with Diverse Biological Functions, Nat. Commun., 2017 8, 1276. (IF=12.12)
\n 2. Yang, P. P.; Luo, Q.; Qi, G. B.; Gao, Y. J.; Li, B. N.; Zhang, J. P.; Wang, L.*; Wang, H*., Host Materials Transformable in Tumor Microenvironment for Homing Theranostics. Adv Mater 2017, 29, 1605869. (IF=19.79)
\n 3. Qi, G.-B.; Zhang, D.; Liu, F.-H.; Qiao, Z.-Y.*; Wang, H*., An \u201cOn-Site Transformation\u201d Strategy for Treatment of Bacterial Infection. Adv. Mater. 2017, 29, 1703461. (IF=19.79)
\n 4. Lin, Y.-X.; Hu, X.-F.; Zhao, Y.; Gao, Y.-J.; Yang, C.; Qiao, S.-L.; Wang, Y.; Yang, P.-P.; Yan, J.; Sui, X.-C.; Qiao, Z.-Y.; Li, L.-L.; Xie, J.-B.; Zhu, S.-Q.; Wu, X.-C.; Li, Y.; Wang, L.*; Wang, H.*, Photothermal Ring Integrated Intraocular Lens for High-Efficient Eye Disease Treatment. Adv. Mater. 2017, 29, 1701617. (IF=19.79)
\n 5.Liu, Y.; Du, J.; Choi, J.-s.; Chen, K.-J.; Hou, S.; Yan, M.; Lin, W.-Y.; Chen, K. S.; Ro, T.; Lipshutz, G. S.; Wu, L.; Shi, L.; Lu, Y.; Tseng, H.-R.*; Wang, H.*, A High-Throughput Platform for Formulating and Screening Multifunctional Nanoparticles Capable of Simultaneous Delivery of Genes and Transcription Factors. Angew. Chem. Int. Ed. 2016, 55, 169-173. (IF=11.99)<\/p>\n

\u738b\u78ca\u7814\u7a76\u5458<\/strong>\uff0c\u56fd\u5bb6\u7eb3\u7c73\u79d1\u5b66\u4e2d\u5fc3\u7814\u7a76\u5458\u3002
\n 2008\u5e74\u5728\u97e9\u56fd\u5168\u5317\u56fd\u7acb\u5927\u5b66\u83b7\u5f97\u5de5\u5b66\u535a\u58eb\u5b66\u4f4d\u5e76\u83b7\u5f97\u4f18\u79c0\u535a\u58eb\u8bba\u6587\u79f0\u53f7\u3002\u8fd15\u5e74\u6765\uff0c\u7814\u7a76\u4e3b\u8981\u96c6\u4e2d\u5728\u539f\u4f4d\u6784\u7b51\u5f0f\u201c\u5728\u4f53\u201d\u4eff\u751f\u751f\u7269\u533b\u7528\u7eb3\u7c73\u6750\u6599\u7684\u5236\u5907\u53ca\u5176\u5728\u91cd\u5927\u75be\u75c5\u7684\u8bca\u7597\u4e2d\u7684\u5e94\u7528\u7814\u7a76\u3002\u738b\u78ca\u7814\u7a76\u5458\u4ee5\u4e3b\u8981\u4f5c\u8005\u5148\u540e\u5728\u56fd\u9645\u8457\u540d\u5b66\u672f\u520a\u7269\u5982 Nat. Commun., Adv. Mater., Angew. Chem. Int. Ed., \u7b49\u6742\u5fd7\u4e0a\u53d1\u8868\u8bba\u658750\u4f59\u7bc7\uff0c\u53c2\u7f16\u4e13\u84572\u90e8\u3002\u7533\u8bf7\u5e76\u83b7\u516c\u5f00\u53d1\u660e\u4e13\u52291\u9879\uff0c\u5b9e\u7528\u65b0\u578b\u4e13\u52291\u9879\u3002\u4f5c\u4e3a\u9879\u76ee\u8d1f\u8d23\u4eba\u627f\u62c5\u4e86\u56fd\u5bb6\u81ea\u7136\u79d1\u5b66\u57fa\u91d1\u9752\u5e74\u57fa\u91d1\u3001\u9762\u4e0a\u9879\u76ee\uff1b\u4f5c\u4e3a\u627f\u62c5\u5355\u4f4d\u8d1f\u8d23\u4eba\u548c\u7814\u7a76\u9aa8\u5e72\u7b49\u627f\u62c5\u53c2\u4e0e\u56fd\u5bb6\u81ea\u7136\u79d1\u5b66\u57fa\u91d1\u59d4\u91cd\u5927\u9879\u76ee\u3001\u5317\u4eac\u5e02\u751f\u547d\u79d1\u5b66\u9886\u57df\u524d\u6cbf\u6280\u672f\u57f9\u80b2\u4e13\u9879\u7b49\u79d1\u7814\u9879\u76ee\u3002
\n \u4ee3\u8868\u6027\u8bba\u6587\uff08*\u4e3a\u901a\u8baf\u4f5c\u8005\uff09
\n 1. Luo, Q.;# Lin, Y.-X.;# Yang, P.-P.;#, etc. Zhang, J.-P.;* Wang, L.;* and Wang, H.*, A Self-destructive Nanosweeper that Captures and Clears Amyloid \u03b2-Peptides, Nature Commun., 2018, 9, 1802. (IF=12.12)
\n 2. Qi, G.-B.; Gao, Y.-J.; Wang, L.;* and Wang, H.*, Self-Assembled Peptide-Based Nanomaterials for Biomedical Imaging and Therapy, Adv. Mater., 2018, 30(22), 1703444. (IF=19.79)
\n 3. Yang, P. P.; Luo, Q.; Qi, G. B.; Gao, Y. J.; Li, B. N.; Zhang, J. P.; Wang, L.*; Wang, H*., Host Materials Transformable in Tumor Microenvironment for Homing Theranostics. Adv Mater. 2017, 29, 1605869. (IF=19.79)
\n 4. Lin, Y.-X.; Hu, X.-F.; Zhao, Y.; Gao, Y.-J.; Yang, C.; Qiao, S.-L.; Wang, Y.; Yang, P.-P.; Yan, J.; Sui, X.-C.; Qiao, Z.-Y.; Li, L.-L.; Xie, J.-B.; Zhu, S.-Q.; Wu, X.-C.; Li, Y.; Wang, L.*; Wang, H.*, Photothermal Ring Integrated Intraocular Lens for High-Efficient Eye Disease Treatment. Adv. Mater. 2017, 29, 1701617. (IF=19.79)
\n 5. Lin, Y.-X.; Qiao, S.-L.;, Wang, Y.; Zhang, R.-X. An, H.-W.; Qiao, Z.-Y.; Wang, L.*; Wang, H.*, An in situ Intracellular Self-Assembly Strategy for Quantitative and Temporal Monitoring Autophagy, ACS Nano, 2017, 11(2), 1826-1839. (IF=13.94)
\n 6. Hu, X.-X.; Qi, G.-B.; Gao, Y.-J.; Lin, Y.-X.; Yang, C. Yang, P. P.; Hao H.-X.*, Wang, L.*; Wang, H.*, Artificial Extracellular Matrix Based on Transformable Nanomaterials for High-Efficient Inhibition of Tumor Invasion and Metastasis, ACS Nano, 2017, 11(4), 4086-4096. (IF=13.94)<\/p>\n

\u674e\u9999\u4e39<\/strong>\uff0c\u5973\uff0c\u535a\u58eb\uff0c\u6559\u6388\u30021982.9-1987.7\u4e1c\u5317\u5e08\u8303\u5927\u5b66\u5316\u5b66\u7cfb\uff0c\u672c\u79d1\uff0c\u83b7\u5b66\u58eb\u5b66\u4f4d\uff1b1990.7-1993.7\u5409\u6797\u519c\u5927\u81ea\u7136\u4e0e\u73af\u5883\u79d1\u5b66\u5b66\u9662\uff0c\u7855\u58eb\u7814\u7a76\u751f\uff0c\u83b7\u7855\u58eb\u5b66\u4f4d\uff1b1998.3-2000.2\u97e9\u56fd\u5168\u5317\u5927\u5b66\u9ad8\u5206\u5b50\u5de5\u5b66\u79d1\uff0c\u7855\u58eb\u7814\u7a76\u751f\uff0c\u83b7\u7855\u58eb\u5b66\u4f4d\uff1b2000.3-2003.2\u97e9\u56fd\u5168\u5317\u5927\u5b66\u9ad8\u5206\u5b50\u5de5\u5b66\u79d1\uff0c\u535a\u58eb\u7814\u7a76\u751f\uff0c\u83b7\u535a\u58eb\u5b66\u4f4d\u30022003.3\uff0d2005.6\u5728\u97e9\u56fd\u5168\u5317\u5927\u5b66\u65b0\u6750\u6599\u7814\u7a76\u4e2d\u5fc3\u535a\u58eb\u540e\u5de5\u4f5c\uff1b1987.7\uff0d1998.2\u5728\u5409\u6797\u519c\u4e1a\u5927\u5b66\u81ea\u7136\u4e0e\u73af\u5883\u79d1\u5b66\u5b66\u9662\u8bb2\u5e08\uff1b2005.10\uff0d\u81f3\u4eca\u53d7\u8058\u4e8e\u4e2d\u5357\u6c11\u65cf\u5927\u5b66\u5316\u5b66\u4e0e\u6750\u6599\u79d1\u5b66\u5b66\u9662\uff0c\u73b0\u4e3a\u6559\u6388\u3002\u4e3b\u8981\u4ece\u4e8b\u5149\u654f\u6027\u71c3\u6599\u7535\u6c60\u8d28\u5b50\u4ea4\u6362\u819c\u6750\u6599\u7684\u7814\u7a76\u548c\u5149\u654f\u6027\u805a\u5408\u7269\u5149\u6ce2\u5bfc\u6750\u6599\u7684\u7814\u7a76\u7b49\u5de5\u4f5c\u3002\u4e3b\u6301\u3001\u5b8c\u6210\u56fd\u5bb6\u81ea\u7136\u79d1\u5b66\u57fa\u91d1\u9879\u76ee\u4e00\u9879\u3001\u56fd\u5bb6\u6559\u80b2\u90e8\u7559\u5b66\u56de\u56fd\u4eba\u5458\u542f\u52a8\u57fa\u91d1\u9879\u76ee1\u9879\u3001\u56fd\u9645\u5408\u4f5c\u9879\u76ee2\u9879\u3001\u6e56\u5317\u7701\u81ea\u7136\u79d1\u5b66\u57fa\u91d1\u9879\u76ee1\u9879\u548c\u5b66\u6821\u81ea\u7136\u79d1\u5b66\u57fa\u91d1\u9879\u76ee1\u9879\uff0c\u53c2\u4e0e\u4e862\u9879\u56fd\u5bb6\u81ea\u7136\u79d1\u5b66\u57fa\u91d1\u9879\u76ee\u7b49\u3002\u5728\u56fd\u5185\u5916\u5b66\u672f\u520a\u7269\u4e0a\u53d1\u8868\u7cfb\u5217\u5b66\u672f\u8bba\u658740\u4f59\u7bc7\uff0c\u5176\u4e2d\u88abSCI\u6536\u5f55\u8bba\u658730\u4f59\u7bc7\u3002
\n \u4ee3\u8868\u6027\u8bba\u6587
\n 1. Rui He, Pushan Wen, Hai-Ning Zhang, Shumeng Guan, Guangyong Xie, Li-Zhong Li, Myong-Hoon Lee, Xiang-Dan Li, In-situ photocrosslinked hydroxide conductive membranes based on photosensitive poly(arylene ether sulfone) block copolymers for anion exchange membrane fuel cells, 2018, JOURNAL OF MEMBRANE SCIENCE, 556, 73-84.
\n 2. Danyun Lei, Xiang-Dan Li, Min-Kang Seo, Myung-Seob Khil, Hak-Yong Kim, Byoung-Suhk Kim, NiCo2O4 nanostructure- decorated PAN\/lignin based carbon nanofiber electrodes with excellent cyclability for flexible hybrid supercapacitors, 2017, POLYMER, 132, 31-40,
\n 3. Pushan Wen, Rui He, Xiang-Dan Li, Myong-Hoon Lee, Syntheses and characterizations of high refractive index and low birefringence polyimides containing spirobifluorene in the side chain, 2017, POLYMER, 117, 76-83.
\n 4. Danyun Lei, Kyung-Hun Song, Xiang-Dan Li, Hak-Yong Kim, Byoung-Suhk Kim, Nanostructured polyaniline\/kenaf-derived 3D porous carbon materials with high cycle stability for supercapacitor electrodes, JOURNAL OF MATERIALS SCIENCE, 52(4), 2158-2168
\n 5. An-Ping Xu,# Pei-Pei Yang,# Chao Yang, Yu-Juan Gao, Xiao-Xiao Zhao, Qiang Luo, Li-Zhong Li,* Lei Wang* and Hao Wang*, Bio-Inspired Metal Ions Regulate Morphological Transformation of Self-Assembled Peptide-Based Nanoparticles, Nanoscale, 2016, 8, 14078\u201314083.<\/p>\n

\u672c\u6587\u7531\u6750\u6599\u4eba\u9ad8\u5206\u5b50\u7ec4\u5927\u5175\u54e5\u4f9b\u7a3f\uff0c\u6750\u6599\u725b\u6574\u7406\u7f16\u8f91\u3002<\/p>\n

\u6b22\u8fce\u5927\u5bb6\u5230\u6750\u6599\u4eba\u5ba3\u4f20\u79d1\u6280\u6210\u679c\u5e76\u5bf9\u6587\u732e\u8fdb\u884c\u6df1\u5165\u89e3\u8bfb\uff0c\u6295\u7a3f\u90ae\u7bb1\uff1atougao@cailiaoren.com<\/a><\/p>\n

\u6295\u7a3f\u4ee5\u53ca\u5185\u5bb9\u5408\u4f5c\u53ef\u52a0\u7f16\u8f91\u5fae\u4fe1\uff1acailiaokefu<\/p>\n","protected":false},"excerpt":{"rendered":"

\u3010\u7814\u7a76\u80cc\u666f\u3011 \u81ea\u7ec4\u88c5\u7eb3\u7c73\u6750\u6599\u662f\u4e00\u7c7b\u5177\u6709\u9ad8\u6548\u6210\u50cf\u548c\u6cbb\u7597\u6548\u679c\u7684\u8bca\u7597\u5242\u3002\u7136\u800c\uff0c\u5728\u590d\u6742\u7684\u751f\u7406\u6761\u4ef6\u4e0b\uff0c\u9884\u7ec4\u88c5\u7684\u7eb3\u7c73\u6750\u6599\u7684\u8d85\u7ed3\u6784\u548c\u6027\u8d28\u4f1a\u6709\u4e9b\u53d7\u635f\u3002\u9274\u4e8e\u81ea\u7ec4\u88c5\u7cfb\u7edf\u7684\u52a8\u6001\u6027\u8d28\u548c…<\/p>\n","protected":false},"author":1004,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[533],"tags":[3862],"class_list":["post-166511","post","type-post","status-publish","format-standard","hentry","category-zongshu","tag-bp"],"_links":{"self":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts\/166511"}],"collection":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/users\/1004"}],"replies":[{"embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=166511"}],"version-history":[{"count":7,"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts\/166511\/revisions"}],"predecessor-version":[{"id":166625,"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts\/166511\/revisions\/166625"}],"wp:attachment":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=166511"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=166511"},{"taxonomy":"post_tag","embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=166511"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}