{"id":165854,"date":"2019-01-25T06:30:59","date_gmt":"2019-01-24T22:30:59","guid":{"rendered":"\/\/m.iemloyee.com\/?p=165854"},"modified":"2019-01-24T18:14:19","modified_gmt":"2019-01-24T10:14:19","slug":"%e5%af%86%e6%ad%87%e6%a0%b9%e5%a4%a7%e5%ad%a6sci-adv-%ef%bc%9a%e9%80%9a%e8%bf%87%e4%bd%93%e7%a7%af%e8%81%9a%e5%90%88%e6%8a%91%e5%88%b6%e5%9b%be%e6%a1%88%e5%8c%96%e5%ae%9e%e7%8e%b0%e5%bf%ab%e9%80%9f","status":"publish","type":"post","link":"\/\/m.iemloyee.com\/?p=165854","title":{"rendered":"\u5bc6\u6b47\u6839\u5927\u5b66Sci. Adv.\uff1a\u901a\u8fc7\u4f53\u79ef\u805a\u5408\u6291\u5236\u56fe\u6848\u5316\u5b9e\u73b0\u5feb\u901f\u3001\u8fde\u7eed\u5730\u589e\u6750\u5236\u9020"},"content":{"rendered":"

\u3010\u5f15\u8a00\u3011<\/strong><\/p>\n

\u589e\u6750\u5236\u9020\uff08AM\uff09\u65b9\u6cd5\u901a\u5e38\u79f0\u4e3a\u4e09\u7ef4\uff083D\uff09\u6253\u5370\uff0c\u53ef\u4ee5\u5236\u9020\u51fa\u4e00\u4e9b\u6bd4\u8f83\u590d\u6742\u7684\u7269\u4f53\uff0c\u5176\u5185\u90e8\u7279\u5f81\u662f\u4f20\u7edf\u65b9\u6cd5\u65e0\u6cd5\u83b7\u5f97\u7684\uff0c\u8be5\u6280\u672f\u901a\u5e38\u901a\u8fc7\u8fde\u7eed\u6dfb\u52a0\u8584\u5c42\u6750\u6599\u4ea7\u751f3D\u7ed3\u6784\u3002\u64cd\u4f5c\u7b80\u5355\u548c\u51e0\u4e4e\u65e0\u9650\u7684\u8bbe\u8ba1\u9009\u62e9\u4f7f\u5f97AM\u975e\u5e38\u9002\u5408\u7528\u4e8e\u751f\u4ea7\u5b9a\u5236\u548c\u539f\u578b\u96f6\u4ef6\uff0c\u5305\u62ec\u4ece\u5b9a\u5236\u533b\u7597\u8bbe\u5907\u5230\u6c7d\u8f66\u548c\u822a\u7a7a\u822a\u5929\u90e8\u4ef6\u7684\u5c0f\u6279\u91cf\u751f\u4ea7\u3002\u76ee\u524d\uff0c\u8bf8\u5982\u70ed\u5851\u6027\u5851\u6599\u3001\u805a\u5408\u7269\u6811\u8102\u548c\u65e0\u673a\u7c89\u672b\u7b49\u6750\u6599\u90fd\u5df2\u88ab\u7528\u4f5cAM\u4ecb\u8d28\u3002\u7acb\u4f53\u5149\u523bAM\u662f\u4e00\u79cd\u6709\u8da3\u7684\u65b9\u6cd5\uff0c\u901a\u8fc7\u4f7f\u7528\u53ef\u5149\u805a\u5408\u6811\u8102\u548c\u56fe\u6848\u5316\u7167\u660e\u6e90\u6765\u56fa\u5316\u6240\u9700\u51e0\u4f55\u5f62\u72b6\u7684\u6a2a\u622a\u9762\u5c42\u3002\u7acb\u4f53\u5149\u523bAM\u7684\u901f\u5ea6\u53d6\u51b3\u4e8e\u6784\u5efa\u5e73\u53f0\u7684\u5e73\u79fb\u65b9\u5411\uff0c\u4e3b\u8981\u53d7\u5230\u56fa\u5316\u805a\u5408\u7269\u7c98\u9644\u5230\u6295\u5f71\u7a97\u53e3\u6216\u6811\u8102\u8868\u9762\u5e72\u6270\u7684\u9650\u5236\uff0c\u56e0\u800c\u9700\u8981\u5728\u8fde\u7eed\u5c42\u4e4b\u95f4\u8fdb\u884c\u8017\u65f6\u7684\u5206\u79bb\u6216\u91cd\u6d82\u6b65\u9aa4\u3002\u56e0\u6b64\uff0c\u8fd9\u4e9b\u7cfb\u7edf\u4e2d\u7684\u6253\u5370\u901f\u5ea6\u8303\u56f4\u4ece\u6bcf\u5c0f\u65f6\u51e0\u6beb\u7c73\u5230\u51e0\u5398\u7c73\u4e0d\u7b49\u3002\u6700\u8fd1\u53d1\u5c55\u7684\u4e00\u79cd\u8fde\u7eed\u6db2\u4f53\u754c\u9762\u751f\u4ea7\u6280\u672f\u901a\u8fc7\u4f7f\u7528\u900f\u6c27\u6027\u6295\u5c04\u7a97\u53e3\u89e3\u51b3\u4e86\u8fd9\u4e00\u7f3a\u9677\uff0c\u4ece\u800c\u5b9e\u73b0\u4e86\u6bcf\u5c0f\u65f6\u51e0\u767e\u6beb\u7c73\u7684\u5e73\u79fb\u901f\u5ea6\u8fde\u7eed\u751f\u4ea7\u96f6\u4ef6\u3002\u7136\u800c\uff0cAM\u7cfb\u7edf\u8fd8\u4e0d\u80fd\u5b9e\u73b0\u65e0\u9700\u79fb\u52a8\u6784\u5efa\u5e73\u53f0\u7684\u4efb\u610f3D\u5bf9\u8c61\u751f\u4ea7\u3002<\/p>\n

\u3010\u6210\u679c\u7b80\u4ecb\u3011<\/strong><\/p>\n

\u8fd1\u65e5\uff0c\u7f8e\u56fd\u5bc6\u6b47\u6839\u5927\u5b66\u7684<\/strong>Martin P. de Beer<\/strong>\u6559\u6388\uff08\u901a\u8baf\u4f5c\u8005\uff09\u548c<\/strong>Harry L. van der Laan<\/strong>\u6559\u6388\uff08\u901a\u8baf\u4f5c\u8005\uff09<\/strong>\u5408\u4f5c\u5f00\u53d1\u4e86\u4e00\u79cdAM\u7cfb\u7edf\uff0c\u5176\u80fd\u591f\u4f7f\u7528\u5355\u6b21\u66dd\u5149\u6253\u53703D\u7ed3\u6784\uff0c\u8fd8\u53ef\u4ee5\u4ee5\u76f8\u5bf9\u8f83\u9ad8\u7684\u7ebf\u901f\u5ea6\u8fde\u7eed\u6253\u5370\u3002\u8be5\u5de5\u827a\u4f7f\u7528\u4e86\u4e00\u4e2a\u6210\u5f62\u5934\uff0c\u5e76\u5411\u4e0a\u62c9\u51fa\u53ef\u5149\u805a\u5408\u6811\u8102\u548c\u4e24\u4e2a\u4e0d\u540c\u6ce2\u957f\u7684\u7167\u660e\u6e90\u3002\u901a\u8fc7\u4ece\u4e0b\u65b9\u900f\u660e\u73bb\u7483\u7a97\u7684\u56fe\u6848\u5316\u7167\u660e\u5f15\u53d1\u6811\u8102\u805a\u5408\uff0c\u800c\u7b2c\u4e8c\u6ce2\u957f\u7684\u7167\u5c04\u6291\u5236\u7d27\u90bb\u73bb\u7483\u7a97\u7684\u805a\u5408\u53cd\u5e94\uff0c\u4ece\u800c\u8fbe\u5230\u6d88\u9664\u7c98\u9644\u548c\u8fde\u7eed\u64cd\u4f5c\u7684\u76ee\u7684\u3002\u8be5\u5de5\u827a\u7684\u6253\u5370\u901f\u5ea6\u7ea6\u4e3a2\u7c73\/\u5c0f\u65f6\uff0c\u800c\u4e14\u80fd\u591f\u4e0e\u591a\u79cd\u6811\u8102\u76f8\u5bb9\u3002\u6b64\u5916\uff0c\u901a\u8fc7\u8c03\u8282\u6bcf\u4e2a\u50cf\u7d20\u4e0a\u7684\u5149\u6e90\u5f3a\u5ea6\uff0c\u8fd8\u53ef\u4ee5\u5728\u6ca1\u6709\u9636\u6bb5\u5e73\u79fb\u7684\u6761\u4ef6\u4e0b\u5b9e\u73b0\u8868\u9762\u5f62\u8c8c\u7684\u56fe\u6848\u5316\u3002\u8be5\u6210\u679c\u4ee5\u9898\u4e3a” Rapid, continuous additive manufacturing by volumetric polymerization inhibition patterning<\/strong>“\u53d1\u8868\u5728\u56fd\u9645\u8457\u540d\u671f\u520aSci. Adv.<\/strong>\u4e0a\u3002<\/p>\n

\u3010\u56fe\u6587\u5bfc\u8bfb\u3011<\/strong><\/p>\n

\u56fe1 \u540c\u6b65\u53cc\u8272\u5149\u5f15\u53d1\u548c\u5149\u6291\u5236<\/strong><\/p>\n

\"\"<\/p>\n

(a) \u901a\u8fc7\u540c\u6b65\u5149\u805a\u5408\u548c\u5149\u6291\u5236\u5b9e\u73b0\u53cc\u8272SLA\u7684\u5149\u5b66\u88c5\u7f6e\uff1b<\/p>\n

(b) \u5149\u5f15\u53d1\u5242CQ\uff1b<\/p>\n

(c) \u5171\u540c\u5f15\u53d1\u5242EDAB\uff1b<\/p>\n

(d) \u5149\u6291\u5236o<\/em>-Cl-HABI\uff1b<\/p>\n

(e) CQ\uff08\u5b9e\u5fc3\u84dd\u7ebf\uff09\u548co<\/em>-Cl-HABI\uff08\u7d2b\u8272\u865a\u7ebf\uff09\u5728\u56db\u6c22\u544b\u5583\u4e2d\u7684\u7d2b\u5916-\u53ef\u89c1\u5149\u8c31\uff1b<\/p>\n

(f) \u4f7f\u7528\u53cc\u8272\u5149\u805a\u5408\/\u5149\u6291\u5236\u7acb\u4f53\u5149\u523b\u7cfb\u7edf\u5206\u522b\u4ee5500\u548c375\u6beb\u7c73\/\u5c0f\u65f6\u6253\u5370\u51fa\u56fa\u4f53\u5757M\uff08\u5de6\uff09\u548c\u62d6\u8239\uff08\u53f3\uff09\uff1b<\/p>\n

(g) \u805a\u5408\u6291\u5236\u4f53\u79ef\u539a\u5ea6\u4e0e\u5165\u5c04\u8f90\u5c04\u6ce2\u957f\u548c\u6811\u8102\u5438\u5149\u5ea6\u7684\u53d8\u5316\u5f3a\u5ea6\u6bd4\u7684\u5173\u7cfb\u3002<\/p>\n

\u56fe2 \u901a\u8fc7\u53cc\u8272\u5149\u5f15\u53d1\u548c\u5149\u6291\u5236\u5b9e\u73b0\u5feb\u901f\u3001\u8fde\u7eed\u7684\u6dfb\u52a0\u5242\u5236\u9020<\/strong><\/p>\n

\"\"<\/p>\n

(a) \u4f7f\u7528\u5149\u6291\u5236\u5b9e\u73b0Argyle\u6a21\u578b\u7684\u8fde\u7eed\u6253\u5370\uff1b<\/p>\n

(b) \u5bf9\u4e8e\u56db\u79cd\u4e19\u70ef\u9178\u916f\u57fa\u6811\u8102\u914d\u65b9\uff0c\u56fa\u5316\u539a\u5ea6\u4e0e\u84dd\u5149\u5242\u91cf\u7684\u5173\u7cfb\uff1b<\/p>\n

(c) \u6700\u5927\u5782\u76f4\u6253\u5370\u901f\u5ea6\u4e0e\u4e0d\u540c\u84dd\u8272\u5438\u5149\u5ea6\u9ad8\u5ea6\u7684\u5173\u7cfb\u3002<\/p>\n

\u56fe3 \u6ce2\u957f\u9009\u62e9\u6027\u5149\u5f15\u53d1\u548c\u81ea\u7531\u57fa\u4ecb\u5bfc\u7684\u94fe\u589e\u957f\u5149\u805a\u5408\u7684\u5149\u6291\u5236<\/strong><\/p>\n

\"\"<\/p>\n

(a) \u53cc\u915aA\u4e59\u6c27\u57fa\u5316\u4e8c\u4e19\u70ef\u9178\u916f(BPAEDA)\uff1b<\/p>\n

(b) \u4e09\u4e59\u4e8c\u9187\u4e8c\u7532\u57fa\u4e19\u70ef\u9178\u916f(TEGDMA)\uff1b<\/p>\n

(c) \u53cc\u915aA\u7518\u6cb9\u4e8c\u7532\u57fa\u4e19\u70ef\u9178\u916f(bisGMA)\uff1b<\/p>\n

(d) \u4e09\u7518\u9187\u4e8c\u4e59\u70ef\u57fa\u919a(TEGDVE)\uff1b<\/p>\n

(e) N-\uff08\u6b63\u4e19\u57fa\uff09\u9a6c\u6765\u9170\u4e9a\u80fa(NPM)\uff1b<\/p>\n

(f) \u5bf9\u4e8eBPAEDA\u6811\u8102\u914d\u65b9\uff0c\u70ef\u70c3\u8f6c\u5316\u7387\u4e0e\u65f6\u95f4\u7684\u5173\u7cfb\uff1b<\/p>\n

(g) \u5bf9\u4e8ebisGMA\/TEGDMA\u6811\u8102\u914d\u65b9\uff0c\u70ef\u70c3\u8f6c\u5316\u7387\u4e0e\u65f6\u95f4\u7684\u5173\u7cfb\uff1b<\/p>\n

(h) \u5bf9\u4e8eTEGDVE\/NPM\u6811\u8102\u914d\u65b9\uff0c\u70ef\u70c3\u8f6c\u5316\u7387\u4e0e\u65f6\u95f4\u7684\u5173\u7cfb\u3002<\/p>\n

\u56fe4 \u53cc\u8272\u5149\u5f15\u53d1\u548c\u5149\u6291\u5236\u5b9e\u73b0\u4e86\u590d\u67423D\u7ed3\u6784\u7684\u53ef\u63a7\u8fdc\u8868\u9762\u56fe\u6848\u5316<\/strong><\/p>\n

\"\"<\/p>\n

(a) \u7528\u4e8e\u5f3a\u5ea6\u56fe\u6848\u6253\u5370\u7684\u88c5\u7f6e\uff1b<\/p>\n

(b) \u4f7f\u7528\u53ef\u53d8\u5f3a\u5ea6\u56fe\u50cf\u53ef\u4ee5\u6309\u50cf\u7d20\u65b9\u5f0f\u8c03\u6574I<\/em>UV<\/sub>\uff0c<\/sub>0<\/sub> \/ I<\/em>blue<\/sub>\uff0c<\/sub>0<\/sub>\uff0c\u4ece\u800c\u4ea7\u751f\u6291\u5236\u9ad8\u5ea6\u7684\u53d8\u5316\u8fdb\u800c\u4ea7\u751f\u5370\u5237\u90e8\u5206\u5f62\u8c8c\uff1b<\/p>\n

(c) \u5bc6\u6b47\u6839\u5927\u5b66\u5bc6\u5c01\u7684\u56db\u7ea7\u5f3a\u5ea6\u56fe\u50cf\uff1b<\/p>\n

(d) \u901a\u8fc7\u5355\u6b21\u5f3a\u5ea6\u56fe\u6848\u66dd\u5149\u4ea7\u751f\u7684\u53ef\u53d8\u539a\u5ea6\u90e8\u4ef6\u3002<\/p>\n

\u3010\u5c0f\u7ed3\u3011<\/strong><\/p>\n

\u672c\u6587\u4e2d\uff0c\u4f5c\u8005\u5c55\u793a\u4e86\u4e00\u79cd\u5feb\u901f\u8fde\u7eed\u7acb\u4f53\u5149\u523b\u589e\u6750\u5236\u9020\u7684\u65b0\u65b9\u6cd5\uff0c\u5176\u901a\u8fc7\u4f7f\u7528\u542b\u6709\u4e92\u8865\u5149\u5f15\u53d1\u5242\u548c\u6291\u5236\u5242\u7269\u8d28\u7684\uff08\u7532\u57fa\uff09\u4e19\u70ef\u9178\u916f\u6811\u8102\u914d\u65b9\u7684\u53cc\u8272\u7167\u5c04\u6765\u5b9e\u73b0\u3002\u5728\u8be5\u65b9\u6cd5\u4e2d\uff0c\u901a\u8fc7\u5728\u4e00\u4e2a\u6ce2\u957f\u5904\u7684\u7167\u5c04\u4ea7\u751f\u7684\u5149\u81f4\u56fe\u6848\u5316\u7684\u805a\u5408\u6291\u5236\u4f53\u79ef\u5728\u7a7a\u95f4\u4e0a\u9650\u5236\u7531\u540c\u65f6\u7167\u5c04\u7684\u7b2c\u4e8c\u6ce2\u957f\u5f15\u53d1\u5149\u805a\u5408\u7684\u533a\u57df\u3002\u6b64\u5916\uff0c\u4f7f\u7528\u8be5\u65b9\u6cd5\u4ea7\u751f\u7684\u6291\u5236\u4f53\u79ef\u4f7f\u5f97\u80fd\u591f\u5c40\u90e8\u63a7\u5236\u805a\u5408\u533a\u57df\u539a\u5ea6\uff0c\u4ece\u800c\u5f71\u54cd\u5355\u6b21\u66dd\u5149\u548c\u5f62\u8c8c\u56fe\u6848\u5316\u3002\u4e0e\u4f20\u7edf\u7684\u5206\u5c42\u589e\u6750\u5236\u9020\u65b9\u6cd5\u53ea\u80fd\u63d0\u4f9b\u7f13\u6162\u7684\u7269\u4f53\u5236\u9020\u901f\u5ea6\u4e0d\u540c\uff0c\u8fde\u7eed\u7acb\u4f53\u6253\u5370\u5927\u5927\u63d0\u9ad8\u4e86\u6253\u5370\u901f\u5ea6\u5e76\u4ea7\u751f\u5177\u6709\u5149\u6ed1\u8868\u9762\u7684\u7269\u4f53\u3002<\/p>\n

\u6587\u732e\u94fe\u63a5\uff1aRapid, continuous additive manufacturing by volumetric polymerization inhibition patterning<\/a>\u00a0<\/strong>\u00a0(Sci. Adv. 2019, DOI: 10.1126\/sciadv.aau8723)<\/p>\n

 <\/p>\n

\u672c\u6587\u7531\u6750\u6599\u4eba\u751f\u7269\u5b66\u672f\u7ec4biotech\u4f9b\u7a3f\uff0c\u6750\u6599\u725b\u5ba1\u6838\u6574\u7406\u3002<\/p>\n

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