{"id":157598,"date":"2018-11-01T06:30:31","date_gmt":"2018-10-31T22:30:31","guid":{"rendered":"\/\/m.iemloyee.com\/?p=157598"},"modified":"2018-10-31T18:26:19","modified_gmt":"2018-10-31T10:26:19","slug":"%e9%99%88%e5%b0%8f%e5%85%83%e3%80%81%e9%bb%84%e9%a3%9e%e9%b9%a4%e3%80%81%e6%af%9b%e5%b3%a5%e4%bc%9f-peter-j-stang-nat-commun-%e4%b8%80%e7%a7%8d%e7%a6%bb%e6%95%a3%e7%9a%84%e6%9c%89%e6%9c%ba","status":"publish","type":"post","link":"\/\/m.iemloyee.com\/?p=157598","title":{"rendered":"\u9648\u5c0f\u5143\u3001\u9ec4\u98de\u9e64\u3001\u6bdb\u5ce5\u4f1f&amp; Peter J. Stang Nat. Commun.: \u4e00\u79cd\u79bb\u6563\u7684\u6709\u673a\u94c2\uff08II\uff09\u91d1\u5c5e\u50ac\u5316\u5242\u4f5c\u4e3a\u764c\u75c7\u5149\u5316\u5b66\u7597\u6cd5\u7684\u591a\u6a21\u5f0f\u6cbb\u7597\u5e73\u53f0"},"content":{"rendered":"<p><strong>\u3010\u5f15\u8a00\u3011<\/strong><\/p>\n<p>\u5728\u8fc7\u53bb\u7684\u51e0\u5341\u5e74\u4e2d\uff0c\u968f\u7740\u751f\u7269\u533b\u5b66\u548c\u5206\u5b50\u751f\u7269\u5b66\u7684\u5feb\u901f\u53d1\u5c55\uff0c\u5bf9\u764c\u75c7\u751f\u7269\u5b66\u7684\u672c\u8d28\u6709\u4e86\u66f4\u6df1\u5c42\u6b21\u7684\u7406\u89e3\u3002\u5728\u5168\u7403\u764c\u75c7\u6b7b\u4ea1\u7387\u7684\u4e0d\u65ad\u4e0a\u5347\u60c5\u51b5\u4e0b\uff0c\u5f00\u53d1\u51fa\u6709\u6548\u7684\u764c\u75c7\u6cbb\u7597\u548c\u8bca\u65ad\u5242\uff0c\u4ee5\u6709\u6548\u7684\u964d\u4f4e\u764c\u75c7\u6b7b\u4ea1\u7387\u5df2\u6210\u4e3a\u91cd\u4e2d\u4e4b\u91cd\u3002\u4f46\u662f\uff0c\u7531\u4e8e\u5316\u7597\u836f\u7269\u6709\u7740\u4e25\u91cd\u7684\u526f\u4f5c\u7528\u548c\u8bf1\u5bfc\u8010\u836f\u6027\u4ea7\u751f\u7684\u7f3a\u9677\uff0c\u6545\u800c\u5316\u5b66\u7597\u6cd5\u5728\u5176\u4e34\u5e8a\u5e94\u7528\u4e2d\uff0c\u7ecf\u5e38\u51fa\u73b0\u80bf\u7624\u7684\u590d\u53d1\u548c\u8f6c\u79fb\u3002\u76ee\u524d\uff0c\u4e3a\u4e86\u52a0\u5f3a\u60a3\u8005\u7684\u6cbb\u7597\u6548\u679c\uff0c\u6bd4\u8f83\u6d41\u884c\u7684\u662f\u5c06\u5177\u6709\u4e0d\u540c\u6297\u764c\u673a\u5236\u4f18\u70b9\u7684\u6cbb\u7597\u65b9\u6cd5\u7ed3\u5408\u8d77\u6765\u4ee5\u5b9e\u73b0<strong>\u201c1+1\uff1e2\u201d<\/strong>\u7684\u6cbb\u7597\u6548\u679c\u3002\u4f8b\u5982\uff0c\u5149\u52a8\u529b\u7597\u6cd5\u7531\u4e8e\u5176\u5fae\u521b\u6027\u3001\u53ef\u5ffd\u7565\u7684\u5168\u8eab\u6bd2\u6027\u3001\u8f83\u5c11\u7684\u526f\u4f5c\u7528\u548c\u6709\u6548\u907f\u514d\u8010\u836f\u6027\u7684\u4f18\u70b9\uff0c\u80fd\u5f88\u597d\u7684\u6539\u5584\u4f20\u7edf\u6cbb\u7597\u6548\u679c\u3002\u4f46\u662f\uff0c\u7531\u4e8e\u758f\u6c34\u6027\u5149\u654f\u5242\u4f1a\u51fa\u73b0\u7684\u4e25\u91cd\u805a\u96c6\uff0c\u4f7f\u5f97\u5176\u5149\u52a8\u529b\u6cbb\u7597\u6548\u679c\u964d\u4f4e\u751a\u81f3\u6d88\u5931\u3002\u56e0\u6b64\u8bbe\u8ba1\u5177\u6709\u9ad8\u5355\u7ebf\u6001\u6c27\uff08<sup>1<\/sup>O<sub>2<\/sub>\uff09\u91cf\u5b50\u4ea7\u7387\uff08QY\uff09\u7684\u5149\u654f\u5242\u4ecd\u7136\u662f\u5177\u6709\u6311\u6218\u6027\u7684\u3002<\/p>\n<p><strong>\u3010\u6210\u679c\u7b80\u4ecb\u3011<\/strong><\/p>\n<p>\u8fd1\u65e5\uff0c<strong>\u7f8e\u56fd\u56fd\u7acb\u536b\u751f\u7814\u7a76\u9662\u7684\u9648\u5c0f\u5143\u6559\u6388\u3001\u6d59\u6c5f\u5927\u5b66\u7684\u9ec4\u98de\u9e64\u6559\u6388\u548c\u6bdb\u5ce5\u4f1f\u526f\u6559\u6388\u4ee5\u53ca\u7f8e\u56fd\u72b9\u4ed6\u5dde\u5927\u5b66\u7684Peter J. Stang\u6559\u6388\uff08\u5171\u540c\u901a\u8baf\u4f5c\u8005\uff09<\/strong>\u7b49\u62a5\u9053\u4e86\u4e00\u79cd\u5229\u7528\u987a\u5f0f\u2014(PEt<sub>3<\/sub>)<sub>2<\/sub>Pt(OTf)<sub>2<\/sub>\u6784\u5efa\u7684\u4e00\u79cd\u79bb\u6563\u7684\u6709\u673a\u94c2\uff08II\uff09\u91d1\u5c5e\u4e19\u70ef\u9178\u916f\u4ee5\u6539\u5584<sup>1<\/sup>O<sub>2<\/sub> QY\uff0c\u4ece\u800c\u5b9e\u73b0\u534f\u540c\u6297\u764c\u7684\u529f\u6548\u3002\u5177\u6709\u4e09\u6a21\u6001\u6210\u50cf\u80fd\u529b\u7684\u91d1\u5c5e\u586b\u5145\u7eb3\u7c73\u9897\u7c92\uff08MNPs\uff09\u53ef\u4ee5\u7cbe\u786e\u8bca\u65ad\u80bf\u7624\u5e76\u5b9e\u65f6\u76d1\u6d4bMNPs\u7684\u9012\u9001\u8fc7\u7a0b\u3001\u751f\u7269\u5206\u5e03\u548c\u6392\u6cc4\u60c5\u51b5\u3002MNPs\u5bf9U87MG\u3001\u8010\u836f\u6027A2780CIS\u548c\u539f\u4f4d\u80bf\u7624\u6a21\u578b\u90fd\u8868\u73b0\u51fa\u4f18\u5f02\u7684\u6297\u80bf\u7624\u8f6c\u79fb\u4f5c\u7528\u548c\u4f18\u5f02\u7684\u6297\u80bf\u7624\u6027\u80fd\uff0c\u5e76\u4e14\u5728\u5355\u6b21\u6cbb\u7597\u540e\u6d88\u9664\u7684\u80bf\u7624\u4e0d\u5728\u590d\u53d1\u3002\u901a\u8fc7\u57fa\u56e0\u82af\u7247\u5206\u6790\u5b9e\u9a8c\u8bc1\u5b9e\u4e86\u4e0d\u540c\u6cbb\u7597\u65b9\u5f0f\u5bf9\u80bf\u7624\u6d88\u9664\u7684\u5404\u81ea\u8d21\u732e\u3002 \u56e0\u6b64\u8fd9\u79cd\u8d85\u5206\u5b50\u5e73\u53f0\u5728\u7cbe\u786e\u7684\u764c\u75c7\u8bca\u65ad\u6cbb\u7597\u4e2d\u5177\u6709\u5de8\u5927\u7684\u6f5c\u529b\u3002\u7814\u7a76\u6210\u679c\u4ee5\u9898\u4e3a<strong>\u201cA discrete organoplatinum(II) metallacage as a multimodality theranostic platform for cancer photochemotherapy\u201d<\/strong>\u53d1\u8868\u5728\u56fd\u9645\u8457\u540d\u671f\u520a<strong>Nat. Commun.<\/strong>\u4e0a\u3002<strong>\u672c\u6587\u7b2c\u4e00\u4f5c\u8005\u4e3a\uff1a\u55bb\u56fd\u707f\u3002<\/strong><\/p>\n<p><strong>\u3010\u56fe\u6587\u5bfc\u8bfb\u3011<\/strong><\/p>\n<p><strong>\u56fe\u4e00\u3001\u7528\u4f5c\u591a\u529f\u80fd\u8bca\u65ad\u6cbb\u7597\u5e73\u53f0\u7684MNPs\u7684\u793a\u610f\u56fe<img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-157599\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2018\/10\/1-32.png\" alt=\"\" width=\"600\" height=\"634\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2018\/10\/1-32.png 600w, \/\/m.iemloyee.com\/wp-content\/uploads\/2018\/10\/1-32-284x300.png 284w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/strong><br \/>\n \uff08a\uff09 TPP\u3001cPt\u3001DSTP\u3001M\u3001mPEG-b-PEBP\u548cRGD-PEGb-PEBP\u7684\u5206\u5b50\u7ed3\u6784\uff1b<\/p>\n<p>\uff08b\uff09 \u80bf\u7624\u7ec4\u7ec7\u4e2dMNPs\u79ef\u805a\u968fEPR\u6548\u5e94\u548c\u53d7\u4f53\u4ecb\u5bfc\u5185\u541e\u4f5c\u7528\u7684\u793a\u610f\u56fe\u53ca\u5176\u5728\u76ae\u4e0b\uff08U87MG\uff09\u3001\u8010\u836f\uff08A2780CIS\uff09\u3001\u539f\u4f4d\uff084T1\u548cLM3\uff09\u80bf\u7624\u6cbb\u7597\u548c\u80ba\u8f6c\u79fb\u4e2d\u7684\u5e94\u7528\u3002<\/p>\n<p><strong>\u56fe\u4e8c\u3001MNPs\u7684\u8868\u5f81\u53ca\u5176PDT\u6548\u5e94<\/strong><br \/>\n <img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-157600\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2018\/10\/2-31.png\" alt=\"\" width=\"600\" height=\"601\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2018\/10\/2-31.png 600w, \/\/m.iemloyee.com\/wp-content\/uploads\/2018\/10\/2-31-150x150.png 150w, \/\/m.iemloyee.com\/wp-content\/uploads\/2018\/10\/2-31-300x300.png 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/>\uff08a\uff09 MNPs\u4e2d\u7684cPt\u7684<sup>31<\/sup>P{<sup>1<\/sup>H}(202.3 MHz, 293 K) \u8868\u5f81\uff1b<\/p>\n<p>\uff08b\uff09 MNPs\u4e2d\u7684M\u7684<sup>31<\/sup>P{<sup>1<\/sup>H}(202.3 MHz, 293 K) \u8868\u5f81\uff1b<\/p>\n<p>\uff08c\uff09 MNPs\u7684AFM\uff1b<\/p>\n<p>\uff08d\uff09 \u7531MPEG-b-PEBP\u548cRGD-PEG-b-PEBP\u5f62\u6210\u7684NPs\u7684DLS\uff0c\u5f62\u6210\u4e4b\u524d\uff08\u9ed1\u7ebf\uff09\u548c\u5f62\u6210\u4e4b\u540e\u5c01\u88c5M\uff08\u7ea2\u7ebf\uff09\uff1b<\/p>\n<p>\uff08e\uff09 \u7531MPEG-b-PEBP\u548cRGD-PEG-b-PEBP\u5f62\u6210\u7684NPs\u7684Zeta\u7535\u4f4d\uff0c\u5f62\u6210\u4e4b\u524d\uff08\u9ed1\u7ebf\uff09\u548c\u5f62\u6210\u4e4b\u540e\u5c01\u88c5M\uff08\u7ea2\u7ebf\uff09\uff1b<\/p>\n<p>\uff08f\uff09 \u4e0d\u540c\u7684\u7167\u5c04\u65f6\u95f4\uff08671 nm\uff0c0.5 W. cm<sup>-2<\/sup>\uff09\u540e\uff0c\u542b\u6709SOSG\u548cTPP\uff08M\u6216MNP\uff09\u7684\u6eb6\u6db2\u5728532 nm\u5904\u7684\u8367\u5149\u5f3a\u5ea6\u53d1\u751f\u53d8\u5316\uff1b<\/p>\n<p>\uff08g\uff09 \u4e0d\u5b58\u5728\u548c\u5b58\u5728NaN3\uff0810.0 \u03bcM\uff09\u7684\u60c5\u51b5\u4e0b\uff0c\u5728\u7167\u5c04\uff08671 nm\uff0c0.5 W.cm<sup>-2<\/sup>, 10 min\uff09\u540e\uff0c\u542b\u6709SOSG\u548cTPP\uff08M\u6216MNP\uff09\u7684\u6eb6\u6db2\u5728532 nm\u5904\u7684\u8367\u5149\u5f3a\u5ea6\u53d1\u751f\u53d8\u5316\uff1b<\/p>\n<p>\uff08h\uff09 M\u7684\u65f6\u95f4\u5bc6\u5ea6\u6cdb\u51fd\u7406\u8bba\u5206\u5b50\u6a21\u62df\u3002<\/p>\n<p><strong>\u56fe\u4e09\u3001MNPs\u7684\u4f53\u5916\u9776\u5411\u9012\u9001\u6d3b\u6027\u548c\u534f\u540c\u6297\u764c\u4f5c\u7528<img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-157601\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2018\/10\/3-32.png\" alt=\"\" width=\"600\" height=\"605\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2018\/10\/3-32.png 600w, \/\/m.iemloyee.com\/wp-content\/uploads\/2018\/10\/3-32-150x150.png 150w, \/\/m.iemloyee.com\/wp-content\/uploads\/2018\/10\/3-32-298x300.png 298w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/strong><br \/>\n \uff08a\uff09 \u7528MNPs\u57f9\u517b\u7684U87MG\u7ec6\u80de2 h\u7684CLSM\u56fe\u50cf\uff1b<\/p>\n<p>\uff08b\uff09 \u7528MNPs\u57f9\u517b\u7684U87MG\u7ec6\u80de4 h\u7684CLSM\u56fe\u50cf\uff1b<\/p>\n<p>\uff08c\uff09 \u7528MNPs\u57f9\u517b\u7684U87MG\u7ec6\u80de4 h\u5e76\u7528\u6e38\u79bbcRGDfK\u9884\u5904\u740630 min\u7684CLSM\u56fe\u50cf\uff1b<\/p>\n<p>\uff08d\uff09 \u5728\u4e0d\u4f7f\u7528cRGDfK\u7684MNPs\u6216NPs\u5904\u7406\u4e0d\u540c\u5b75\u80b2\u65f6\u95f4\u540e\uff0cU87MG\u7ec6\u80de\u7684\u5e73\u5747\u8367\u5149\u5f3a\u5ea6\uff08MFI\uff09\uff1b<\/p>\n<p>\uff08e\uff09 \u5728\u4e0d\u4f7f\u7528cRGDfK\u7684MNPs\u6216NPs\u5904\u7406\u4e0d\u540c\u5b75\u80b2\u65f6\u95f4\u540e\uff0cU87MG\u7ec6\u80de\u5185\u7684\u94c2\u542b\u91cf\uff1b<\/p>\n<p>\uff08f\uff09 \u7528\u4e0d\u540c\u7ed9\u836f\u5904\u7406\u7684U87MG\u7ec6\u80de\u7684\u7ec6\u80de\u6bd2\u6027\uff1b<\/p>\n<p>\uff08g\uff09 U87MG\u7ec6\u80de\u7684\u8367\u5149\u56fe\u50cf\u5728\u4e0d\u540c\u5904\u7406\u540e\u4e0e\u9499\u9ec4\u7eff\u7d20AM\/PI\u5171\u67d3\u8272\uff1b<\/p>\n<p>\uff08h\uff09 \u4e0d\u540c\u5904\u7406\u8bf1\u5bfcU87MG\u7ec6\u80de\u51cb\u4ea1\u7684FCM\u5206\u6790\u3002<\/p>\n<p><strong>\u56fe\u56db\u3001\u4f53\u5185\u4e09\u6001\u6210\u50cf<\/strong><br \/>\n <img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-157602\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2018\/10\/4-31.png\" alt=\"\" width=\"600\" height=\"743\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2018\/10\/4-31.png 600w, \/\/m.iemloyee.com\/wp-content\/uploads\/2018\/10\/4-31-242x300.png 242w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/>\uff08a\uff09 TPP\u3001M\u548cMNPs\u7684\u8367\u5149\u5149\u8c31\uff1b<\/p>\n<p>\uff08b\uff09 \u5728\u5c0f\u9f20\u8840\u6e05\u4e2d\u5b75\u80b224 h\u540e\uff0c<sup>64<\/sup>Cu@MNP\u7684\u653e\u5c04TLC\u8272\u8c31\u56fe\uff1b<\/p>\n<p>\uff08c\uff09 Mn@MNPs\uff08\u6216DTPA-Gd\uff09\u7684T1-1\u4e0eMn\uff08\u6216Gd\uff09\u6d53\u5ea6\u7684\u5173\u7cfb\u66f2\u7ebf\uff1b<\/p>\n<p>\uff08d\uff09 \u4ece\u4e0d\u540cMn\uff08\u6216Gd\uff09\u6d53\u5ea6\u7684Mn@MNPs\uff08\u6216DTPA-Gd\uff09\u6c34\u6eb6\u6db2\u4e2d\u83b7\u5f97\u7684T1\u52a0\u6743MRI\u7ed3\u679c\uff087T\uff09\uff1b<\/p>\n<p>\uff08e\uff09 \u9759\u8109\u6ce8\u5c04U87MG\u8377\u7624\u88f8\u9f20\u7684NIRFI\uff1b<\/p>\n<p>\uff08f\uff09 \u5728\u6ce8\u5c04MNPs\u540e24 h\uff0c\u4ece\u643a\u5e26U87MG\u80bf\u7624\u7684\u5c0f\u9f20\u5206\u79bb\u7684\u4e3b\u8981\u5668\u5b98\u7684\u79bb\u4f53\u56fe\u50cf\uff1b<\/p>\n<p>\uff08g\uff09 \u5728\u6ce8\u5c04<sup>64<\/sup>Cu@MNPs\uff08150 \u03bcCi\uff09\u540e2, 4, 6, 12, 24\u548c48 h\uff0c\u643a\u5e26U87MG\u80bf\u7624\u7684\u88f8\u9f20\u7684PET\u56fe\u50cf\uff1b<\/p>\n<p>\uff08h\uff09 \u5c0f\u9f20\u9884\u6ce8\u5c04\u548c\u6ce8\u5c04Mn@MNPs\u540e\u7684\u4f53\u5185T1\u52a0\u6743\u8f74\u5411MRI\u56fe\u50cf\uff087T\uff09\uff1b<\/p>\n<p>\uff08i\uff09 <sup>64<\/sup>Cu@MNPs\u5728\u8840\u6db2\u3001\u809d\u810f\u3001\u813e\u810f\u548c\u80bf\u7624\u4e2d\u7684\u751f\u7269\u5206\u5e03\u7684\u65f6\u95f4- \u6d3b\u6027\u66f2\u7ebf\uff08n = 3\uff09\uff1b<\/p>\n<p>\uff08j\uff09 \u6ce8\u5c04<sup>64<\/sup>Cu@MNPs\u540e48 h\uff0c\u4e3b\u8981\u5668\u5b98\u4e2d<sup>64<\/sup>Cu@MNPs\u7684\u5b9a\u91cf\u751f\u7269\u5206\u5e03\uff1b<\/p>\n<p>\uff08k\uff09 \u6ce8\u5c04Mn@MNPs\u6216DTPA-Gd\uff08n = 3\uff09\u540e2, 4, 6\u548c24 h\u80bf\u7624\u90e8\u4f4d\u7684SNR\u6bd4\u7387\u7684\u5b9a\u91cf\u5206\u6790\u3002<\/p>\n<p><strong>\u56fe\u4e94\u3001\u4f53\u5185\u534f\u540c\u6297\u80bf\u7624\u4f5c\u7528<img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-157603\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2018\/10\/5-17.png\" alt=\"\" width=\"600\" height=\"513\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2018\/10\/5-17.png 600w, \/\/m.iemloyee.com\/wp-content\/uploads\/2018\/10\/5-17-300x257.png 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/strong><br \/>\n \uff08a\uff09 \u6ce8\u5c04cPt\u548cMNPs\u540e\u8840\u6d46\u94c2\u6d53\u5ea6\u4e0e\u65f6\u95f4\u7684\u5173\u7cfb\uff1b<\/p>\n<p>\uff08b\uff09 \u6ce8\u5c04MNPs\u540e\u4e0d\u540c\u65f6\u95f4\u70b9Pt\u7684\u751f\u7269\u5206\u5e03\uff08n = 4\uff09\uff1b<\/p>\n<p>\uff08c\uff09 \u6ce8\u5c04cPt\uff082 mg Pt\/kg\uff09\u540e\u4e0d\u540c\u65f6\u95f4\u70b9Pt\u7684\u751f\u7269\u5206\u5e03\uff08n = 4\uff09\uff1b<\/p>\n<p>\uff08d\uff09 \u4e0d\u540c\u914d\u65b9\u540e\u5c0f\u9f20\u7684\u80bf\u7624\u751f\u957f\u66f2\u7ebf\uff08n = 9\uff09\uff1b<\/p>\n<p>\uff08e\uff09 \u63a5\u53d7\u4e0d\u540c\u7684\u5236\u5242\u540e\uff0c\u5c0f\u9f20\u7684U87MG\u80bf\u7624\u7684\u91cd\u91cf\uff1b<\/p>\n<p>\uff08f\uff09 \u7528\u4e0d\u540c\u5236\u5242\u5904\u7406\u540e\u643a\u5e26U87MG\u80bf\u7624\u7684\u5c0f\u9f20\u7684Kaplan-Meier\u56fe\uff1b<\/p>\n<p>\uff08g\uff09 \u7528\u5404\u79cd\u5236\u5242\u7ed9\u836f\u7684\u5c0f\u9f20\u6536\u96c6\u7684\u80bf\u7624\u7ec4\u7ec7\u7684H\uff06E\u3001TUNEL\u548cKi67\u67d3\u8272\u3002<\/p>\n<p><strong>\u56fe\u516d\u3001\u7528\u4e0d\u540c\u5236\u5242\u5904\u7406\u7684\u5c0f\u9f20\u7684\u80bf\u7624\u7684\u5168\u57fa\u56e0\u8868\u8fbe\u5206\u6790<img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-157604\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2018\/10\/6-12.png\" alt=\"\" width=\"600\" height=\"782\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2018\/10\/6-12.png 600w, \/\/m.iemloyee.com\/wp-content\/uploads\/2018\/10\/6-12-230x300.png 230w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/strong><br \/>\n \uff08a\uff09 GeneChip\u00aePrimeView\u2122\u4eba\u7c7b\u57fa\u56e0\u8868\u8fbe\u7684\u70ed\u56fe\u7528\u5316\u7597\u3001PDT\u6216\u5149\u5316\u5b66\u7597\u6cd5\u6cbb\u7597\u7684\u5c0f\u9f20\u9635\u5217\uff1b<\/p>\n<p>\uff08b\uff09 \u4e0e\u672a\u5904\u7406\u7684\u5bf9\u7167\u7ec4\u76f8\u6bd4\uff0c\u7528MNPs\u5904\u7406\u7684\u80bf\u7624\u7684\u6539\u53d8\u7684\u9057\u4f20\u8c31\uff1b<\/p>\n<p>\uff08c\uff09 \u4e0e\u672a\u5904\u7406\u7684\u5bf9\u7167\u7ec4\u76f8\u6bd4\uff0c\u7528TPPNPs+L\u5904\u7406\u7684\u80bf\u7624\u7684\u6539\u53d8\u7684\u9057\u4f20\u8c31\uff1b<\/p>\n<p>\uff08d\uff09 \u4e0e\u672a\u5904\u7406\u7684\u5bf9\u7167\u7ec4\u76f8\u6bd4\uff0c\u7528MNPs+L\u5904\u7406\u7684\u80bf\u7624\u7684\u6539\u53d8\u7684\u9057\u4f20\u8c31\uff1b<\/p>\n<p>\uff08e\uff09 \u7ef4\u6069\u56fe\u663e\u793a\u6765\u81ea\u4e09\u79cd\u4e0d\u540c\u5904\u7406\u7684\u663e\u7740\u6539\u53d8\u7684\u57fa\u56e0\u4e2d\u7684\u5171\u540c\u7279\u5f81\u7684\u6570\u91cf\uff1b<\/p>\n<p>\uff08f\uff09 \u9009\u62e9\u6f5c\u5728\u7684\u57fa\u56e0\u9776\u6807\u53c2\u4e0e\u80bf\u7624\u6d88\u9000\u4ee5\u54cd\u5e94\u4e0d\u540c\u7684\u6cbb\u7597\u65b9\u6cd5\u3002<\/p>\n<p><strong>\u56fe\u4e03\u3001\u9488\u5bf9\u6297\u6027\u764c\u75c7\u6a21\u578b\u7684\u4f53\u5185\u6297\u80bf\u7624\u529f\u6548<\/strong><br \/>\n <img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-157605\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2018\/10\/7-7.png\" alt=\"\" width=\"600\" height=\"497\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2018\/10\/7-7.png 600w, \/\/m.iemloyee.com\/wp-content\/uploads\/2018\/10\/7-7-300x249.png 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/>\uff08a\uff09 \u7528\u4e0d\u540c\u7ed9\u836f\u5904\u7406\u7684A2780CIS\u7ec6\u80de\u7684\u7ec6\u80de\u6bd2\u6027\uff1b<\/p>\n<p>\uff08b\uff09 \u4e0d\u540c\u5904\u7406\u540eA2780CIS\u7ec6\u80de\u819c\u8054\u86cb\u767dV\/PI\u5206\u6790\uff1b<\/p>\n<p>\uff08c\uff09 \u4e0d\u540c\u5904\u7406\u540e\u5c0f\u9f20\u7684\u4f53\u5185\u80bf\u7624\u751f\u957f\u6291\u5236\u66f2\u7ebf\uff08n = 9\uff09\uff1b<\/p>\n<p>\uff08d\uff09 \u4e0d\u540c\u5904\u7406\u540e\u5c0f\u9f20\u7684\u4f53\u5185\u80bf\u7624\u4f53\u91cd\u53d8\u5316\uff08n = 9\uff09\uff1b<\/p>\n<p>\uff08e\uff09 \u4e0d\u540c\u5904\u7406\u540eA2780CIS\u80bf\u7624\u7684\u91cd\u91cf\uff1b<\/p>\n<p>\uff08f\uff09 \u7528\u4e0d\u540c\u5904\u7406\u65b9\u6cd5\u5904\u7406\u7684\u5c0f\u9f20\u7684Kaplan-Meier\u56fe\uff1b<\/p>\n<p>\uff08g\uff09 H\uff06E\u548cKi67\u5206\u6790\u4e0d\u540c\u5904\u7406\u540e\u7684\u80bf\u7624\u7ec4\u7ec7\u3002<\/p>\n<p><strong>\u56fe\u516b\u3001\u539f\u4f4d\u4e73\u817a\u764c\u7684\u6cbb\u7597\u53ca\u5bf9\u80ba\u8f6c\u79fb\u7684\u6291\u5236\u4f5c\u7528<\/strong><br \/>\n <img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-157606\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2018\/10\/8-3.png\" alt=\"\" width=\"600\" height=\"662\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2018\/10\/8-3.png 600w, \/\/m.iemloyee.com\/wp-content\/uploads\/2018\/10\/8-3-272x300.png 272w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/>\uff08a\uff09 \u4e00\u6b21\u6ce8\u5c04\u540e\u7528PBS\u3001\u5149\u3001cPt\u3001MNPs\u3001TPPNPs+L\u6216MNPs+L\u5904\u7406\u7684\u5c0f\u9f20\u7684\u80bf\u7624\u4f53\u79ef\u53d8\u5316\uff08n = 8\uff09\uff1b<\/p>\n<p>\uff08b\uff09 \u7528\u4e0d\u540c\u5236\u5242\u5904\u7406\u7684\u5c0f\u9f20\u7684\u80bf\u7624\u91cd\u91cf\uff1b<\/p>\n<p>\uff08c\uff09 \u7528\u4e0d\u540c\u5236\u5242\u5904\u7406\u7684\u5e26\u6709\u539f\u4f4d4T1\u4e73\u817a\u80bf\u7624\u7684\u5c0f\u9f20\u7684Kaplan-Meier\u5b58\u6d3b\u66f2\u7ebf\uff1b<\/p>\n<p>\uff08d\uff09 \u6bcf\u7ec4\u80bf\u7624\u7ec4\u7ec7\u7684H\uff06E\u67d3\u8272\uff1b<\/p>\n<p>\uff08e\uff09 \u6bcf\u7ec4\u5207\u9664\u80ba\u7684\u4ee3\u8868\u6027\u56fe\u50cf\uff1b<\/p>\n<p>\uff08f\uff09 H\uff06E\u67d3\u8272\u540e\u5404\u7ec4\u80ba\u7ec4\u7ec7\u8f6c\u79fb\u7076\u7684\u7ec4\u7ec7\u5b66\u68c0\u67e5\uff1b<\/p>\n<p>\uff08g\uff09 \u7528\u4e0d\u540c\u5236\u5242\u5904\u7406\u7684\u5c0f\u9f20\u6536\u83b7\u7684\u539f\u4f4d\u80bf\u7624\u7684\u7167\u7247\u56fe\u50cf\uff1b<\/p>\n<p>\uff08h\uff09 \u6bcf\u7ec4\u80ba\u90e8\u5b58\u5728\u80bf\u7624\u7ed3\u8282\u7684\u6570\u91cf\uff1b<\/p>\n<p>\uff08i\uff09 \u5404\u7ec4\u80ba\u90e8\u80bf\u7624\u8986\u76d6\u7387\uff1b<\/p>\n<p>\uff08j\uff09 \u6ce8\u5c04\u540e\u7b2c14 d\u7528\u4e0d\u540c\u5236\u5242\u5904\u7406\u7684\u5c0f\u9f20\u7684PET\/CT\u56fe\u50cf\u3002<\/p>\n<p><strong>\u56fe\u4e5d\u3001\u6cbb\u7597\u539f\u4f4d\u809d\u764c<\/strong><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-157607\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2018\/10\/9-1.png\" alt=\"\" width=\"600\" height=\"565\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2018\/10\/9-1.png 600w, \/\/m.iemloyee.com\/wp-content\/uploads\/2018\/10\/9-1-300x283.png 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/>\uff08a\uff09 \u7528PBS\u5904\u7406\u7684\u539f\u4f4dLM3\u80bf\u7624\u7684\u5c0f\u9f20\u7684\u80bf\u7624\u4f53\u79ef\u53d8\u5316\uff1b<\/p>\n<p>\uff08b\uff09 \u7528cPt\u5904\u7406\u7684\u539f\u4f4dLM3\u80bf\u7624\u7684\u5c0f\u9f20\u7684\u80bf\u7624\u4f53\u79ef\u53d8\u5316\uff1b<\/p>\n<p>\uff08c\uff09 \u7528MNPs\u5904\u7406\u7684\u539f\u4f4dLM3\u80bf\u7624\u7684\u5c0f\u9f20\u7684\u80bf\u7624\u4f53\u79ef\u53d8\u5316\uff1b<\/p>\n<p>\uff08d\uff09 \u7528TPPNPs + L\u5904\u7406\u7684\u539f\u4f4dLM3\u80bf\u7624\u7684\u5c0f\u9f20\u7684\u80bf\u7624\u4f53\u79ef\u53d8\u5316\uff1b<\/p>\n<p>\uff08e\uff09 \u7528MNPs + L\u5904\u7406\u7684\u539f\u4f4dLM3\u80bf\u7624\u7684\u5c0f\u9f20\u7684\u80bf\u7624\u4f53\u79ef\u53d8\u5316\uff1b<\/p>\n<p>\uff08f\uff09 \u7528\u4e0d\u540c\u5236\u5242\u5904\u7406\u7684\u5e26\u6709\u539f\u4f4dLM3\u80bf\u7624\u7684\u5c0f\u9f20\u7684Kaplan-Meier\u5b58\u6d3b\u66f2\u7ebf\uff1b<\/p>\n<p>\uff08g\uff09 \u7528\u4e0d\u540c\u5236\u5242\u5904\u7406\u7684\u5c0f\u9f20\u6536\u96c6\u7684\u542b\u6709LM3\u80bf\u7624\u7684\u809d\u7ec4\u7ec7\u7684\u7167\u7247\u56fe\u50cf\uff1b<\/p>\n<p>\uff08h\uff09 \u6bcf\u7ec4\u809d\u7ec4\u7ec7\u7684H\uff06E\u548cKi67\u67d3\u8272\uff1b<\/p>\n<p>\uff08i\uff09 \u7528\u4e0d\u540c\u5236\u5242\u5904\u7406\u7684\u5c0f\u9f20\u7684PET\/CT\u56fe\u50cf\uff1b<\/p>\n<p>\uff08j\uff09 \u7528\u4e0d\u540c\u914d\u65b9\u5904\u7406\u7684\u5c0f\u9f20\u7684MRI\u56fe\u50cf\u3002<\/p>\n<p><strong>\u3010\u603b\u7ed3\u3011<\/strong><\/p>\n<p>\u7814\u7a76\u4e86\u591a\u7ec4\u5206\u534f\u8c03\u9a71\u52a8\u7684\u81ea\u7ec4\u88c5\u7b56\u7565\u5236\u5907\u4e86\u4e00\u79cd\u590d\u6742\u7684\u535f\u5549\u57fa\u91d1\u5c5e\uff0c\u4f5c\u4e3a\u5236\u9020MNPs\u7684\u8bca\u65ad\u6cbb\u7597\u5e73\u53f0\u3002\u901a\u8fc7\u4e24\u79cd\u7279\u6b8a\u7684\u4e24\u4eb2\u6027\u7684\u4e8c\u5d4c\u6bb5\u805a\u5408\u7269\uff08mPEG-b-PEBP\u548cRGD-PEG-b-PEBP\uff09\u7ec4\u88c5\u5f97\u5230\u7684MNPs\u8868\u73b0\u51fa\u8f83\u957f\u7684\u8840\u6db2\u5faa\u73af\u65f6\u95f4\u548c\u8f83\u9ad8\u7684\u80bf\u7624\u79ef\u7d2f\uff0c\u5e76\u5229\u7528EPR\u6548\u5e94\u548c\u4e3b\u52a8\u9776\u5411\u80fd\u529b\u5728\u6297\u764c\u529f\u6548\u63d0\u9ad8\u548c\u51cf\u5c11\u4e86\u5bf9\u6b63\u5e38\u7ec4\u7ec7\u7684\u526f\u4f5c\u7528\u3002\u540c\u65f6\uff0c MNPs\u4e2d\u7684\u535f\u5549\u7684\u8367\u5149\u53d1\u5c04\u548c<sup>1<\/sup>O<sub>2<\/sub>\u4ea7\u751f\u91cf\u5b50\u4ea7\u7387\u663e\u7740\u589e\u52a0\uff0c\u6709\u5229\u4e8eNIRFI\u548cPDT\u3002\u5e76\u4e14\u901a\u8fc7\u87af\u5408<sup>64<\/sup>Cu\u6216\u987a\u78c1\u6027Mn\uff0c\u4f7f\u5f97<sup>64<\/sup>Cu@MNPs\u6216Mn@MNPs\u6210\u4e3a\u5f88\u597d\u7684PET\u6210\u50cf\u548cMRI\u8bd5\u5242\uff0c\u53ef\u4ee5\u7cbe\u786e\u8bca\u65ad\u80bf\u7624\u5e76\u5b9e\u65f6\u76d1\u6d4bMNPs\u7684\u9012\u9001\u8fc7\u7a0b\u3001\u751f\u7269\u5206\u5e03\u548c\u6392\u6cc4\u7684MNPs\u3002\u5316\u7597\u548cPDT\u7684\u7ec4\u5408\u5728\u4f53\u5916\u548c\u4f53\u5185\u663e\u793a\u51fa\u4f18\u5f02\u7684\u534f\u540c\u529f\u6548\u3002\u5229\u7528U87MG\u3001\u8010\u987a\u94c2\u7684A2780CIS\u548c\u539f\u4f4d\uff084T1\u548cLM3\uff09\u80bf\u7624\u6a21\u578b\u8bc1\u660e\u4e86\u5176\u826f\u597d\u7684\u6297\u80bf\u7624\u6548\u679c\u3002\u8be5\u7814\u7a76\u4e3a\u5f00\u53d1\u591a\u529f\u80fd\u6cbb\u7597\u7cfb\u7edf\u63d0\u4f9b\u4e86\u4e00\u79cd\u65b0\u7684\u7b56\u7565\uff0c\u4e3a\u4e0b\u4e00\u4ee3\u7eb3\u7c73\u836f\u7269\u7684\u5236\u5907\u63d0\u4f9b\u4e86\u65b0\u65b9\u5411\u3002<\/p>\n<p><strong>\u6587\u732e\u94fe\u63a5\uff1a<a href=\"https:\/\/www.nature.com\/articles\/s41467-018-06574-7\" target=\"_blank\" rel=\"noopener\">A discrete organoplatinum(II) metallacage as a multimodality theranostic platform for cancer photochemotherapy<\/a><\/strong>\uff08Nat. Commun., <strong>2018<\/strong>, DOI: 10.1038\/s41467-018-06574-7\uff09<\/p>\n<p style=\"text-align: left;\"><strong>\u901a\u8baf\u4f5c\u8005\u7b80\u4ecb\uff1a<\/strong><\/p>\n<p><strong>\u9ec4\u98de\u9e64\u6559\u6388\uff1a\u6559\u80b2\u90e8\u957f\u6c5f\u5b66\u8005\u5956\u52b1\u8ba1\u5212\u7279\u8058\u6559\u6388\u3001\u56fd\u5bb6\u6770\u51fa\u9752\u5e74\u79d1\u5b66\u57fa\u91d1\u83b7\u5f97\u8005\u3001\u56fd\u5bb6\u4e07\u4eba\u8ba1\u5212\u9886\u519b\u4eba\u624d\u3001\u6d59\u6c5f\u5927\u5b66\u6c42\u662f\u7279\u8058\u6559\u6388\u3001\u535a\u58eb\u751f\u5bfc\u5e08\u3002<\/strong>2005\u5e7412\u6708\u8d77\u4efb\u6d59\u6c5f\u5927\u5b66\u5316\u5b66\u7cfb\u6559\u6388\uff0c\u7b79\u5efa\u8d85\u5206\u5b50\u5316\u5b66\u7814\u7a76\u5c0f\u7ec4\u30022008\u5e743\u6708\u8d77\u4efb\u6d59\u6c5f\u5927\u5b66\u6c42\u662f\u7279\u8058\u6559\u6388\u3002\u4e3b\u8981\u4ece\u4e8b\u8d85\u5206\u5b50\u5316\u5b66\u65b9\u9762\u7684\u7814\u7a76\u5de5\u4f5c\uff0c2003\u5e74\u81f3\u4eca\u5df2\u5728\u56fd\u9645\u6838\u5fc3\u5316\u5b66\u671f\u520a\u4e0a\u53d1\u8868\u8d85\u5206\u5b50\u5316\u5b66\u76f8\u5173SCI\u8bba\u6587230\u4f59\u7bc7\uff0c\u5305\u62ec5\u7bc7Accounts of Chemical Research\u30013\u7bc7Chemical Reviews\u30017\u7bc7Chemical Society Reviews\u30011\u7bc7Progress in Polymer Science\u30011\u7bc7Nature Chemistry\u30013\u7bc7PNAS\u300131\u7bc7Journal of the American Chemical Society\u30015\u7bc7Angewandte Chemie International Edition\u30019\u7bc7Advanced Materials\u3001\u548c2\u7bc7Nature Communications\u3002\u53d1\u8868\u7684\u8bba\u6587\u5df2\u88ab\u5f15\u752817747\u6b21\uff0ch-index\u4e3a71\u3002\u4e24\u7bc7\u901a\u8baf\u4f5c\u8005\u8bba\u6587\u5165\u9009\u201c\u4e2d\u56fd\u767e\u7bc7\u6700\u5177\u5f71\u54cd\u56fd\u9645\u5b66\u672f\u8bba\u6587\u201d\u3002\u5230\u76ee\u524d\u4e3a\u6b62\u83b7\u5f97\u7684\u4e3b\u8981\u5956\u52b1\u548c\u8363\u8a89\u6709\uff1a2004\u5e74\u83b7\u56fd\u5bb6\u4f18\u79c0\u81ea\u8d39\u7559\u5b66\u751f\u5956\u5b66\u91d1\u548cVirginia Polytechnic Institute &amp; State University \u4f18\u79c0\u7855\u58eb\u8bba\u6587William Preston \u5956\uff08William Preston Award for MS thesis\uff09\uff0c2005\u5e74\u83b7The Sigma Xi Society Research Award\uff0c2006\u5e74\u83b7Virginia Polytechnic Institute &amp; State University\u4f18\u79c0\u535a\u58eb\u8bba\u6587\u5956\uff08Outstanding Dissertation Award\uff09\uff0c2006\u5e74\u5165\u9009\u6d59\u6c5f\u7701\u201c\u94b1\u6c5f\u4eba\u624d\u8ba1\u5212\u201d\uff0c 2007\u5e74\u83b7\u7f8e\u56fd\u674e\u6c0f\u57fa\u91d1\u4f1a\u6770\u51fa\u6210\u5c31\u5956\u5e76\u5165\u9009\u6d59\u6c5f\u7701\u201c\u65b0\u4e16\u7eaa151\u4eba\u624d\u5de5\u7a0b\u201d\uff0c2008\u5e74\u88ab\u8bc4\u9009\u4e3a\u6d59\u6c5f\u5927\u5b66\u201c\u5341\u4f73\u9752\u5e74\u5c97\u4f4d\u80fd\u624b\u201d\uff0c2009\u5e74\u83b7Thieme Chemistry Journals Award\u5e76\u5165\u9009\u6559\u80b2\u90e8 \u201c\u65b0\u4e16\u7eaa\u4f18\u79c0\u4eba\u624d\u652f\u6301\u8ba1\u5212\u201d\uff0c2010\u5e74\u83b7\u5f97\u6d59\u6c5f\u7701\u6770\u51fa\u9752\u5e74\u79d1\u5b66\u57fa\u91d1\u9879\u76ee\u8d44\u52a9\u548cVirginia Polytechnic Institute &amp; State University\u7684the Outstanding Recent Graduate Alumnus Award\uff0c2010\u5e74\u5165\u9009\u6d59\u6c5f\u7701\u201c\u6d77\u5916\u9ad8\u5c42\u6b21\u4eba\u624d\u5f15\u8fdb\u8ba1\u5212\u201d\uff0c2011\u5e74\u83b7\u56fd\u5bb6\u6770\u51fa\u9752\u5e74\u79d1\u5b66\u57fa\u91d1\u9879\u76ee\u8d44\u52a9\uff0c\u6307\u5bfc\u535a\u58eb\u751f\u83b7\u5f972011\u5e74\u5168\u56fd\u767e\u7bc7\u4f18\u79c0\u535a\u58eb\u8bba\u6587\u63d0\u540d\u5956\uff0c2012\u5e74\u5165\u9009\u82f1\u56fd\u7687\u5bb6\u5316\u5b66\u4f1a\u4f1a\u58eb\uff08Fellow of the Royal Society of Chemistry, FRSC\uff09\uff0c2013\u5e74\u5165\u9009\u56fd\u5bb6\u521b\u65b0\u4eba\u624d\u63a8\u8fdb\u8ba1\u5212\u4e2d\u9752\u5e74\u79d1\u6280\u521b\u65b0\u9886\u519b\u4eba\u624d\uff0c2013\u5e74\u5165\u9009\u4e9a\u6d32\u5316\u5b66\u5927\u4f1aAsian Rising Star\uff0c2013\u5e74\u83b7\u5f97\u6d59\u6c5f\u7701\u9752\u5e74\u79d1\u6280\u5956\uff0c2014\u5e74\u83b7\u4e2d\u56fd\u5316\u5b66\u4f1a-\u963f\u514b\u82cf\u8bfa\u8d1d\u5c14\u5316\u5b66\u5956\uff0c2015\u5e74\u83b7\u82f1\u56fd\u7687\u5bb6\u5316\u5b66\u4f1aCram Lehn Pedersen Prize in Supramolecular Chemistry\uff0c2016\u5e74\u83b7\u82f1\u56fd\u7687\u5bb6\u5316\u5b66\u4f1aPolymer Chemistry Lectureship Award\uff0c2016\u5e74\u5165\u9009\u56fd\u5bb6\u4e07\u4eba\u8ba1\u5212\u9886\u519b\u4eba\u624d\uff0c2017\u5e74\u5165\u9009\u6559\u80b2\u90e8\u957f\u6c5f\u5b66\u8005\u5956\u52b1\u8ba1\u5212\u7279\u8058\u6559\u6388\uff0c2018\u5e74\u83b7\u82f1\u56fd\u7687\u5bb6\u5b66\u4f1aNewton Advanced Fellowship\u3002\u5e94\u9080\u62c5\u4efbChemical Society Reviews\u3001Accounts of Chemical Research\u3001Chemical Reviews\u3001Chemical Communications\u3001Advanced Materials\u3001\u548cMaterials Chemistry Frontiers\u7684\u5ba2\u5ea7\u7f16\u8f91\u3002\u5e94\u9080\u62c5\u4efbChemical Society Reviews\uff082012\u5e74\u8d77\uff09\u3001Chemical Communications\uff082012\u5e74\u8d77\uff09\u3001\u5316\u5b66\u5b66\u62a5\uff082012\u5e74-2018\u5e74\uff09\u3001Macromolecules \uff082014\u5e74-2017\u5e74\uff09\u3001ACS Macro Letters\uff082014\u5e74-2017\u5e74\uff09\u3001Polymer Chemistry\uff082014\u5e74\u8d77\uff09\u3001Materials Chemistry Frontiers\uff082016\u5e74\u8d77\uff09\u3001\u9ad8\u5206\u5b50\u5b66\u62a5\uff082016\u5e74\u8d77\uff09\u3001\u4e2d\u56fd\u5316\u5b66\u5feb\u62a5\uff082018\u5e74\u8d77\uff09\u7b49\u7684\u987e\u95ee\u7f16\u59d4\u6216\u7f16\u59d4\u3002\u73b0\u4efb\u4e2d\u56fd\u5316\u5b66\u4f1a\u9ad8\u5206\u5b50\u5b66\u79d1\u59d4\u5458\u4f1a\u59d4\u5458\uff0c\u4e2d\u56fd\u5316\u5b66\u4f1a\u8d85\u5206\u5b50\u5316\u5b66\u4e13\u4e1a\u59d4\u5458\u4f1a\u526f\u4e3b\u4efb\u59d4\u5458\uff0c\u6d59\u6c5f\u7701\u5316\u5b66\u4f1a\u7406\u4e8b\u3002<\/p>\n<p><strong>\u8bfe\u9898\u7ec4\u7f51\u9875\uff1a<a href=\"http:\/\/www.chem.zju.edu.cn\/~huangfeihe\/\" target=\"_blank\" rel=\"noopener\">http:\/\/www.chem.zju.edu.cn\/~huangfeihe\/<\/a><\/strong><\/p>\n<p><strong>\u672c\u6587\u7531\u6750\u6599\u4eba\u751f\u7269\u6750\u6599\u7ec4\u3001\u7eb3\u7c73\u7ec4\u5c0f\u80d6\u7eb8\u7f16\u8bd1\uff0c\u6750\u6599\u4eba\u6574\u7406\u3002<\/strong><\/p>\n<p>\u6b22\u8fce\u5927\u5bb6\u5230\u6750\u6599\u4eba\u5ba3\u4f20\u79d1\u6280\u6210\u679c\u5e76\u5bf9\u6587\u732e\u8fdb\u884c\u6df1\u5165\u89e3\u8bfb\uff0c\u6295\u7a3f\u90ae\u7bb1\uff1a<strong>tougao@cailiaoren.com.<\/strong><\/p>\n<p>\u6295\u7a3f\u4ee5\u53ca\u5185\u5bb9\u5408\u4f5c\u53ef\u52a0\u7f16\u8f91\u5fae\u4fe1\uff1a<strong>cailiaokefu.<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u3010\u5f15\u8a00\u3011 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