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Lieber\u6559\u6388\u4ece\u4e8b\u535a\u58eb\u8bba\u6587\u5de5\u4f5c\u3002\u6234\u5b8f\u67701997\u5e74\u52a0\u5165\u7f8e\u56fd\u65af\u5766\u798f\u5927\u5b66\uff0c\u5148\u540e\u62c5\u4efb\u52a9\u7406\u6559\u6388\u3001\u7ec8\u751f\u6559\u6388\u3001\u6b63\u6559\u6388\u3001\u8363\u8a89\u6559\u6388\uff1b2002\u5e74\u83b7\u5f97\u7f8e\u56fd\u5316\u5b66\u4f1a\u7eaf\u7cb9\u5316\u5b66\u5956\uff1b2005\u5e74\u73b0\u4efb\u804c\u4e8e\u7f8e\u56fd\u65af\u5766\u798f\u5927\u5b66\uff0c\u5e76\u4e8e2016\u5e74\u5f53\u9009\u4e3a\u7f8e\u56fd\u79d1\u5b66\u9662\u9662\u58eb\u3002\u57282000-2010\u5e74\u5168\u7403\u9876\u5c16\u4e00\u767e\u5316\u5b66\u5bb6\u540d\u4eba\u5802\u699c\u5355\u603b\u6392\u540d\u7b2c7\uff0c\u534e\u4eba\u7b2c1\u3002<\/p>\n<p>\u6234\u5b8f\u6770\u7684\u7814\u7a76\u65b9\u5411\u5305\u62ec\uff1a\u65b0\u578b\u4e00\u7ef4\u7eb3\u7c73\u6750\u6599\u4e0e\u5fae\u7c73\/\u7eb3\u7c73\u534a\u5bfc\u4f53\u7ed3\u6784\u7684\u96c6\u6210\uff1b\u5229\u7528\u65b0\u578b\u63a2\u9488\u548c\u65b0\u7684\u6210\u50cf\u673a\u7406\u7684\u626b\u63cf\u63a2\u9488\u663e\u5fae\u6280\u672f\u53ca\u5176\u5e94\u7528\u3002<\/p>\n<p>\u6234\u5b8f\u6770\u5728\u6210\u50cf\u9886\u57df\u7684\u7814\u7a76\u4e3b\u8981\u4e3a\u5229\u7528\u78b3\u7eb3\u7c73\u7ba1\u7684\u7ea2\u5916\u6ce2\u957f\u8367\u5149\u663e\u793a\u52a8\u7269\u5668\u5b98\u6210\u50cf\u3002\u6234\u5b8f\u6770\u56e2\u961f\u65e9\u57282008\u5e74\u5c31\u5c06\u78b3\u7eb3\u7c73\u7ba1\u8f7d\u836f\u5e94\u7528\u5728\u80bf\u7624\u6cbb\u7597\u4e2d\uff0c\u53c8\u57282011\u5e74\u5c06\u6210\u50cf\u529f\u80fd\u52a0\u5165\u3002\u56e0\u800c\u5728\u8f7d\u836f\u7684\u540c\u65f6\uff0c\u5b9e\u73b0\u836f\u7269\u7684\u8ffd\u8e2a\u3002\u8bfe\u9898\u7ec4\u5229\u7528\u78b3\u7eb3\u7c73\u7ba11000\u52301400\u7eb3\u7c73\u7684\u6ce2\u957f\u6210\u50cf\uff0c\u6539\u6ce2\u6bb5\u7684\u6ce2\u957f\u5177\u6709\u8f83\u5c0f\u7684\u6563\u5c04\uff0c\u53ef\u4ee5\u5728\u5c0f\u9f20\u4f53\u5185\u83b7\u5f97\u6e05\u6670\u7684\u6210\u50cf\u7ed3\u679c\u3002\u76f8\u5bf9\u4e8e\u4f20\u7edf\u7684CT\u6210\u50cf\u548cX\u5149\u6210\u50cf\uff0c\u78b3\u7eb3\u7c73\u7ba1\u7684\u7ea2\u5916\u6210\u50cf\u5bf9\u751f\u7269\u4f53\u7684\u8f90\u5c04\u66f4\u5c0f\uff0c\u4e14\u6210\u672c\u66f4\u4f4e\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-155846\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2018\/10\/fig1-1.jpg\" alt=\"\" width=\"600\" height=\"367\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2018\/10\/fig1-1.jpg 600w, \/\/m.iemloyee.com\/wp-content\/uploads\/2018\/10\/fig1-1-300x184.jpg 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/p>\n<p><strong><b>\u5218\u658c\uff08\u65b0\u52a0\u5761\u56fd\u7acb\u5927\u5b66\uff09<\/b><\/strong><\/p>\n<p>\u5218\u658c\u5206\u522b\u4e8e1995\u5e74\u548c1998\u5e74\u5728\u5357\u4eac\u5927\u5b66\u5316\u5b66\u7cfb\u83b7\u5f97\u5b66\u58eb\u548c\u7855\u58eb\u5b66\u4f4d\uff0c\u53c8\u4e8e2001\u5e74\u5728\u65b0\u52a0\u5761\u56fd\u7acb\u5927\u5b66\u83b7\u5f97\u535a\u58eb\u5b66\u4f4d\u3002\u4e4b\u540e\uff0c\u5218\u658c\u5728\u7f8e\u56fd\u52a0\u5dde\u5927\u5b66\u5723\u82ad\u82ad\u62c9\u5206\u6821\u8ddf\u968fGuillermo C. Bazan\u8fdb\u884c\u535a\u58eb\u540e\u7814\u7a76\u3002\u5218\u658c\u6559\u6388\u4ece2005\u5e74\u52a0\u5165\u65b0\u52a0\u5761\u56fd\u7acb\u5927\u5b66\uff0c\u73b0\u5728\u662f\u65b0\u52a0\u5761\u56fd\u7acb\u5927\u5b66\u5316\u5de5\u7cfb\u6b63\u6559\u6388\u548c\u7cfb\u4e3b\u4efb\uff0c\u540c\u65f6\u4e5f\u662fPolymer Chemistry\u7684\u526f\u4e3b\u7f16\u3002<\/p>\n<p>\u5218\u658c\u7684\u7814\u7a76\u9886\u57df\u5305\u62ec\u5177\u6709\u805a\u96c6\u8bf1\u5bfc\u53d1\u5149\u6027\u8d28\u7684\u8367\u5149\u63a2\u9488\u5728\u751f\u7269\u6210\u50cf\u9886\u57df\u4e2d\u7684\u5e94\u7528\u4ee5\u53ca\u5171\u8f6d\u9ad8\u5206\u5b50\u5728\u7ec6\u80de\u6210\u50cf\u548c\u68c0\u6d4b\u4e2d\u7684\u5e94\u7528\u3002<\/p>\n<p>\u5218\u658c\u56e2\u961f\u6700\u8fd1\u62a5\u5bfc\u4e86\u4e00\u79cd\u57fa\u4e8e\u805a\u96c6\u8bf1\u5bfc\u53d1\u5149\u7684\u8367\u5149\u201c\u70b9\u4eae\u201d\u63a2\u9488\uff0cBCN-TPET-TEG\uff0c\u4ee5\u751f\u7269\u6b63\u4ea4\u7684\u65b9\u5f0f\u5b9e\u73b0\u751f\u7269\u4f53\u5185\u80bf\u7624\u6807\u8bb0\u3002BCN-TPET-TEG\u7531AIE\u5149\u654f\u5242\u3001\u65e0\u94dc\u70b9\u51fb\u7684\u73af\u8f9b\u7094\u548c\u4eb2\u6c34\u4e09\u7518\u9187\u94fe\u7ec4\u6210\u3002\u8fd9\u4e2a\u63a2\u9488\u5177\u6709\u5728\u53ef\u89c1\u5149\u533a\u8f83\u5bbd\u7684\u5438\u6536\u5149\u8c31\uff0c\u8fd1\u7ea2\u5916\u53d1\u5c04\u548cROS\u4ea7\u7387\u9ad8\u8fbe59.1%\u7684\u4f18\u70b9\u3002\u7531\u4e8e\u4e09\u7518\u9187\u94fe\u7684\u4eb2\u6c34\u6027\u53caAIE\u8367\u5149\u5206\u5b50\u7684\u53d1\u5149\u7279\u6027\uff0cBCN-TPET-TEG\u5728\u6c34\u4e2d\u53d1\u5149\u8f83\u5f31\u3002\u4f46\u662f\u5f53\u5176\u4e0e\u901a\u8fc7\u7ec6\u80de\u4ee3\u8c22\u5f15\u5165\u80bf\u7624\u7ec6\u80de\u8868\u9762\u7684\u53e0\u6c2e\u57fa\u56e2\u53cd\u5e94\u540e\uff0c\u63a2\u9488\u7684\u8367\u5149\u589e\u5f3a\uff0c\u53ef\u5b9e\u73b0\u5feb\u901f\u7684\u80bf\u7624\u7279\u5f02\u6027\u6210\u50cf\uff0c\u548c\u5b9e\u73b0\u80bf\u7624\u5149\u52a8\u529b\u6cbb\u7597\u3002<\/p>\n<p><img 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Applied Bio 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loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-155848\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2018\/10\/fig3-1.jpg\" alt=\"\" width=\"600\" height=\"906\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2018\/10\/fig3-1.jpg 600w, \/\/m.iemloyee.com\/wp-content\/uploads\/2018\/10\/fig3-1-199x300.jpg 199w\" sizes=\"(max-width: 600px) 100vw, 600px\" 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Biotechnology\u3002\u6d66\u4f83\u88d4\u56e2\u961f\u81ea2015\u5e746\u6708\u6210\u7acb\u81f3\u4eca\uff0c\u8be5\u56e2\u961f\u5df2\u5728\u56fd\u9645\u4e3b\u6d41\u671f\u520a\u4e0a\u53d1\u8868\u9ad8\u6c34\u5e73\u6587\u7ae050\u591a\u7bc7\uff08\u5305\u62ecNat. Biotechnol., Nat. Nanotechnol., Nat. Commun., J. Am. Chem. Soc., Angew. Chem. Int. Ed., Adv. Mater., Nano. Lett.\u7b49\uff09\u3002\u6d66\u4f83\u88d4\u81f3\u4eca\u7d2f\u8ba1\u53d1\u8868\u9ad8\u6863\u6b21\u6587\u7ae0100\u591a\u7bc7\uff0cSCI H-index=48\u3002<\/p>\n<p>\u6d66\u4f83\u88d4\u56e2\u961f\u8fd1\u671f\u62a5\u5bfc\u4e86\u4e00\u79cd\u4eb2\u6c34\u6027\u7684PPV\u884d\u751f\u7269\uff0c\u53ef\u4ee5\u5728\u751f\u7269\u4ecb\u8d28\u4e2d\u81ea\u7ec4\u88c5\u5f62\u6210\u7eb3\u7c73\u7c92\u5b50\uff08SPPVN\uff09\u548c\u8fd1\u7ea2\u5916\u4f59\u8f89\u53d1\u5149\u3002\u6b64\u6750\u6599\u5728\u53ef\u5728\u5c0f\u9f20\u4f53\u5185\u5b9e\u73b0\u8f6c\u79fb\u80bf\u7624\u6210\u50cf\u3002\u76f8\u5bf9\u4e8e\u4ece\u758f\u6c34PPV\u884d\u751f\u7269\u5236\u5907\u5f97\u5230\u7684\u7eb3\u7c73\u7c92\u5b50\uff08PPVP\uff09\uff0cSPPVN\u62e5\u6709\u8f83\u5c0f\u7684\u7c92\u5f84\u3001\u66f4\u9ad8\u7684\u80fd\u91cf\u8f6c\u79fb\u6548\u7387\u548c\u66f4\u5f3a\u7684\u53d1\u5149\u5f3a\u5ea6\u3002\u9664\u6b64\u4e4b\u5916\uff0c\u56e0\u4e3aSPPVN\u6bd4PPVP-\u805a\u4e59\u70ef\u9187\u5177\u6709\u66f4\u9ad8\u7684PEG\u5bc6\u5ea6\uff0cSPPVN\u53ef\u4ee5\u5728\u80bf\u7624\u4e2d\u66f4\u597d\u5730\u79ef\u805a\u3002\u8fd9\u4e9b\u4f18\u70b9\u4f7f\u5f97SPPVN\u53ef\u5728\u80bf\u7624\u6210\u50cf\u4e2d\u5177\u6709\u975e\u5e38\u597d\u7684\u5e94\u7528\u524d\u666f\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-155849\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2018\/10\/fig4-1.jpg\" alt=\"\" width=\"600\" height=\"427\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2018\/10\/fig4-1.jpg 600w, \/\/m.iemloyee.com\/wp-content\/uploads\/2018\/10\/fig4-1-300x214.jpg 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/p>\n<p><strong><b>\u53c2\u8003\u6587\u732e<\/b><\/strong><\/p>\n<p><strong><b>1<\/b><\/strong><strong><b>.<\/b><\/strong><a href=\"https:\/\/www.researchgate.net\/publication\/323916888_A_bright_organic_NIR-II_nanofluorophore_for_three-dimensional_imaging_into_biological_tissues?_sg=z3FmJ1jL9s_ZRU7XP8WxAlCR23uWxtLyG4mjBphRQzogZHVYiczQU_noLJui67uT7s_2T5fMEFKKbglmOIGMgZRV2A38ZevNl-sgxoHw._ktx2GSzkobmC-zILiB62nfvPgQdW81eWaKekvfVXXkOy1TbIUIDgYhXrNlZ69e-odXR3ojKHSoZllS1DR4wWw\"><strong><b>A bright organic NIR-II nanofluorophore for three-dimensional imaging into biological tissues<\/b><\/strong><\/a><\/p>\n<p><strong><b>Nat<\/b><\/strong><strong><b>. C<\/b><\/strong><strong><b>o<\/b><\/strong><strong><b>m<\/b><\/strong><strong><b>mun<\/b><\/strong><strong><b>. 201<\/b><\/strong><strong><b>8<\/b><\/strong><strong><b>, <\/b><\/strong><strong><b>9<\/b><\/strong><strong><b>, <\/b><\/strong><strong><b>1171<\/b><\/strong><\/p>\n<p><strong><b>2.<a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/anie.201805446\" target=\"_blank\" rel=\"noopener\">A Light-Up Probe with Aggregation-Induced Emission for Real-Time Bio-orthogonal Tumor Labeling and Image-Guided Photodynamic Therapy<\/a><\/b><\/strong><\/p>\n<p><strong><b>Angew<\/b><\/strong><strong><b>. Chem. <\/b><\/strong><strong><b>Int. Ed<\/b><\/strong><strong><b>. 201<\/b><\/strong><strong><b>8<\/b><\/strong><strong><b>, <\/b><\/strong><strong><b>57<\/b><\/strong><strong><b>, <\/b><\/strong><strong><b>10182<\/b><\/strong><strong><b>&#8211;<\/b><\/strong><strong><b>10186<\/b><\/strong><\/p>\n<p><strong><b>3.<a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/anie.201807158\" target=\"_blank\" rel=\"noopener\">Conjugated Polymer Nanoparticles Appending Photo-Responsive Units for Controlled Drug Delivery, Release and Imaging<\/a><\/b><\/strong><\/p>\n<p><strong><b>Angew<\/b><\/strong><strong><b>. Chem. <\/b><\/strong><strong><b>Int. Ed<\/b><\/strong><strong><b>. 201<\/b><\/strong><strong><b>8<\/b><\/strong><strong><b>, <\/b><\/strong><strong><b>57<\/b><\/strong><strong><b>, <\/b><\/strong><strong><b>13114<\/b><\/strong><strong><b>&#8211;<\/b><\/strong><strong><b>13119<\/b><\/strong><\/p>\n<p><strong><b>4.<a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/adma.201801331\" target=\"_blank\" rel=\"noopener\">Self-assembled semiconducting polymer nanoparticles for ultrasensitive near-infrared afterglow imaging of metastatic tumors.<\/a><\/b><\/strong><\/p>\n<p><strong><b>Adv. Mater., 2018, 30, 1801331.<\/b><\/strong><\/p>\n<p><strong><b>\u00a0<\/b><\/strong><\/p>\n<p><strong><b>\u6ce8\uff1a\u4ee5\u4e0a\u4ec5\u4ecb\u7ecd\u4e86\u51e0\u4e2a\u5177\u6709\u4ee3\u8868\u6027\u7684\u7814\u7a76\u56e2\u961f\uff0c\u8fd8\u6709\u5f88\u591a\u5176\u4ed6\u4f18\u79c0\u7684\u56e2\u961f\u540c\u6837\u6709\u5f88\u591a\u4f18\u79c0\u7684\u5de5\u4f5c\uff0c\u4f46\u662f\u7531\u4e8e\u7bc7\u5e45\u7684\u5173\u7cfb\uff0c\u6211\u4eec\u5728\u8fd9\u91cc\u5c31\u4e0d\u80fd\u4e00\u4e00\u5217\u4e3e\u4e86\u3002<\/b><\/strong><\/p>\n<p>&nbsp;<\/p>\n<p>\u672c\u6587\u7531\u6750\u6599\u4eba\u7f16\u8f91\u90e8\u4f9b\u7a3f\uff0c\u6750\u6599\u725b\u7f16\u8f91\u6574\u7406\u3002<\/p>\n<p>\u6b22\u8fce\u5927\u5bb6\u5230\u6750\u6599\u4eba\u5ba3\u4f20\u79d1\u6280\u6210\u679c\u5e76\u5bf9\u6587\u732e\u8fdb\u884c\u6df1\u5165\u89e3\u8bfb\uff0c\u6295\u7a3f\u90ae\u7bb1tougao@cailiaoren.com\u3002<\/p>\n<p><strong><b>\u6295\u7a3f\u4ee5\u53ca\u5185\u5bb9\u5408\u4f5c\u53ef\u52a0\u7f16\u8f91\u5fae\u4fe1\uff1a<\/b><\/strong><strong><b>cailiaokefu<\/b><\/strong><strong><b>\uff0c\u6211\u4eec\u4f1a\u9080\u8bf7\u5404\u4f4d\u8001\u5e08\u52a0\u5165\u4e13\u5bb6\u7fa4\u3002<\/b><\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u5728\u521a\u521a\u843d\u4e0b\u5e37\u5e55\u7684\u8bfa\u8d1d\u5c14\u5956\u8bc4\u9009\u4e2d\uff0c\u201c\u5149\u5b66\u954a\u5b50\u201d\u6458\u53d6\u4e86\u8bfa\u8d1d\u5c14\u7269\u7406\u5b66\u5956\u7684\u6842\u51a0\u3002\u8fd9\u4e5f\u662f\u7ee7\u7eff\u8272\u8367\u5149\u86cb\u767d\u548c\u8d85\u5206\u8fa8\u5149\u5b66\u6210\u50cf\u4e4b\u540e\uff0c\u5149\u5b66\u76f8\u5173\u9886\u57df\u8fd1\u5e74\u6765\u7684\u7b2c\u4e09\u6b21\u8bfa\u5956\uff0c\u5145\u5206\u8bf4\u660e\u4e86\u5149\u5b66&#8230;<\/p>\n","protected":false},"author":7336,"featured_media":155846,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2810],"tags":[3609,3608],"class_list":["post-155845","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-huizong","tag-3609","tag-3608"],"_links":{"self":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts\/155845"}],"collection":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/users\/7336"}],"replies":[{"embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=155845"}],"version-history":[{"count":1,"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts\/155845\/revisions"}],"predecessor-version":[{"id":155850,"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts\/155845\/revisions\/155850"}],"wp:featuredmedia":[{"embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/media\/155846"}],"wp:attachment":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=155845"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=155845"},{"taxonomy":"post_tag","embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=155845"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}