{"id":132179,"date":"2018-03-29T06:30:06","date_gmt":"2018-03-28T22:30:06","guid":{"rendered":"\/\/m.iemloyee.com\/?p=132179"},"modified":"2018-03-28T10:36:35","modified_gmt":"2018-03-28T02:36:35","slug":"adv-funct-mater%ef%bc%9a%e9%81%97%e4%bc%a0%e6%8e%a7%e5%88%b6%e7%9a%84%e8%b6%85%e9%a1%ba%e7%a3%81%e6%80%a7%e9%93%81%e8%9b%8b%e7%99%bd%e6%ba%b6%e9%85%b6%e4%bd%93%e5%8c%85%e8%a3%b9%e5%a4%9a%e6%a8%a1","status":"publish","type":"post","link":"\/\/m.iemloyee.com\/?p=132179","title":{"rendered":"Adv. Funct. Mater\uff1a\u9057\u4f20\u63a7\u5236\u7684\u8d85\u987a\u78c1\u6027\u94c1\u86cb\u767d\u6eb6\u9176\u4f53\u5305\u88f9\u591a\u6a21\u5f0f\u548c\u591a\u5c3a\u5ea6\u6210\u50cf\u548c\u4f4e\u7ec4\u7ec7\u8870\u51cf"},"content":{"rendered":"

\u3010\u5f15\u8a00\u3011<\/strong><\/p>\n

\u5206\u5b50\u6210\u50cf\u548c\u81f4\u52a8\u65b9\u6cd5\u5bf9\u4e8e\u7ec6\u80de\u7f51\u7edc\u7684\u529f\u80fd\u5206\u79bb\u662f\u6709\u4ef7\u503c\u7684\uff0c\u7279\u522b\u662f\u5982\u679c\u5b83\u4eec\u63d0\u4f9b\u6df1\u5ea6\u7ec4\u7ec7\u7a7f\u900f\u5e76\u4e14\u4e0e\u5b8c\u6574\u6a21\u578b\u7cfb\u7edf\u4e2d\u7684\u7eb5\u5411\u7814\u7a76\u517c\u5bb9\u3002\u6b64\u5916\uff0c\u5bf9\u5206\u5b50\u4f20\u611f\u5668\u548c\u81f4\u52a8\u5668\u7684\u8868\u8fbe\u6a21\u5f0f\u8fdb\u884c\u9057\u4f20\u63a7\u5236\u662f\u975e\u5e38\u9700\u8981\u7684\uff0c\u56e0\u4e3a\u5b83\u6709\u52a9\u4e8e\u786e\u5b9a\u7279\u5b9a\u7ec6\u80de\u7fa4\u4f53\u5bf9\u7ec4\u7ec7\u529f\u80fd\u7684\u8d21\u732e\u3002\u7eb3\u7c73\u6750\u6599\u7531\u4e8e\u5176\u53ef\u5b9a\u5236\u7684\u7279\u6027\u5bf9\u751f\u7269\u533b\u5b66\u5e94\u7528\u5177\u6709\u5de8\u5927\u7684\u4ef7\u503c\u3002\u7136\u800c\uff0c\u7eb3\u7c73\u6750\u6599\u7684\u6750\u6599\u7279\u6027\u53ef\u4ee5\u901a\u8fc7\u4e0e\u7ec4\u7ec7\u7684\u76f8\u4e92\u4f5c\u7528\u800c\u53d1\u751f\u663e\u8457\u7684\u6539\u53d8\uff0c\u56e0\u6b64\u5728\u7279\u5b9a\u7684\u751f\u7269\u73af\u5883\u4e2d\u8bc4\u4f30\u5b83\u4eec\u4ee5\u4e86\u89e3\u548c\u5b9a\u5236\u5b83\u4eec\u7684\u5f71\u54cd\u975e\u5e38\u91cd\u8981\u3002<\/p>\n

\u3010\u6210\u679c\u7b80\u4ecb\u3011<\/strong><\/p>\n

\u8fd1\u65e5\uff0c\u5fb7\u56fd\u4ea5\u59c6\u970d\u5179\u8054\u5408\u4f1aGil G. Westmeyer\uff08\u901a\u8baf\u4f5c\u8005\uff09<\/strong>\u7b49\u4eba\u5bf9\u9057\u4f20\u63a7\u5236\u7cfb\u7edf\u9488\u5bf9\u8d85\u987a\u78c1\u6027\u94c1\u86cb\u767d\u7684\u7ec6\u80de\u6444\u53d6\u548c\u968f\u540e\u5411\u6eb6\u9176\u4f53\u7684\u8fd0\u8f93\u8fdb\u884c\u4e86\u4f18\u5316\u3002\u5149\u5438\u6536\u78c1\u94c1\u86cb\u767d\u7684\u9ad8\u5c40\u90e8\u6d53\u5ea6\u5728\u5149\u58f0\u6210\u50cf\u4e2d\u4ea7\u751f\u5f3a\u70c8\u7684\u5bf9\u6bd4\u5e76\u5141\u8bb8\u8fc7\u8868\u8fbe\u94c1\u86cb\u767d\u53d7\u4f53\u7ec6\u80de\u7684\u9009\u62e9\u6027\u5149\u70e7\u8680\u3002\u751f\u7269\u78c1\u6027\u7eb3\u7c73\u9897\u7c92\u7684\u57fa\u56e0\u63a7\u5236\u6444\u53d6\u4e5f\u5f3a\u70c8\u5730\u589e\u5f3a\u4e86\u4e09\u6b21\u8c10\u6ce2\u7684\u4ea7\u751f\uff0c\u8fd9\u662f\u7531\u4e8e\u6eb6\u9176\u4f53\u4e2d\u5305\u88f9\u7684\u94c1\u86cb\u767d\u7684\u78c1\u94c1-\u86cb\u767d\u8d28\u754c\u9762\u5f15\u8d77\u7684\u6298\u5c04\u7387\u53d8\u5316\u3002\u78c1\u6027\u94c1\u86cb\u767d\u7684\u9009\u62e9\u6027\u5438\u6536\u8fd8\u4f7f\u5f97\u5176\u80fd\u591f\u901a\u8fc7\u78c1\u5171\u632f\u6210\u50cf\u7075\u654f\u68c0\u6d4b\u8868\u8fbe\u53d7\u4f53\u7684\u7ec6\u80de\uff0c\u4ee5\u53ca\u6709\u6548\u7684\u78c1\u6027\u7ec6\u80de\u5206\u9009\u548c\u64cd\u4f5c\u3002\u4ee4\u4eba\u60ca\u8bb6\u7684\u662f\uff0c\u89c2\u5bdf\u5230\u6eb6\u9176\u4f53\u5305\u88f9\u7684\u78c1\u6027\u94c1\u86cb\u767d\u7684\u963b\u65ad\u6e29\u5ea6\u663e\u8457\u589e\u52a0\uff0c\u8fd9\u5141\u8bb8\u901a\u8fc7\u5c40\u90e8\u78c1\u70ed\u7597\u5bf9\u57fa\u56e0\u5b9a\u4e49\u7684\u7ec6\u80de\u7fa4\u8fdb\u884c\u7279\u5f02\u6027\u6d88\u878d\u3002\u76f8\u5173\u7814\u7a76\u4ee5\u9898\u4e3a\u201cGenetically Controlled Lysosomal Entrapment of Superparamagnetic Ferritin for Multimodal and Multiscale Imaging and Actuation with Low Tissue Attenuation<\/strong>\u201d\u53d1\u8868\u5728\u4e86Adv. Funct. Mater.<\/strong>\u4e0a\u3002<\/p>\n

\u3010\u56fe\u6587\u5bfc\u8bfb\u3011<\/strong><\/p>\n

\u56fe1 \u57fa\u56e0\u63a7\u5236\u6444\u53d6\u548c\u94c1\u86cb\u767d\u53d8\u4f53\u6eb6\u9176\u4f53\u9776\u5411\u7684\u7b80\u56fe<\/strong><\/p>\n

\"\"<\/p>\n

A\uff09\u57fa\u56e0\u7cfb\u7edf\u7531\u57fa\u56e0\u7f16\u7801\u7684\u94c1\u86cb\u767d\u53d7\u4f53Tim-2\uff0cTfR1\u6216Scara5\u7ec4\u6210<\/p>\n

B\uff09\u5728\u4e0e\u8fc7\u8868\u8fbe\u94c1\u86cb\u767d\u53d7\u4f53Tim-2\u548c\u6eb6\u9176\u4f53\u9776\u5411mCherry\uff08mCherryLT\uff0c\u7ea2\u8272\uff09\u7684\u7ec6\u80de\u5b75\u80b2\u4e4b\u524d\uff0c\u7528Alexa-488\uff08\u7eff\u8272\uff09\u6807\u8bb0eFTH+L\u548chFTH-<\/p>\n

\u56fe2 \u94c1\u86cb\u767d\u6444\u53d6\u4f5c\u4e3a\u5149\u58f0\u7684\u62a5\u544a\u57fa\u56e0\u673a\u5236<\/strong><\/p>\n

\"\"A\uff09\u4e0e\u7f3a\u4e4fTim-2\u8fc7\u8868\u8fbe\u7684\u5bf9\u7167\u7ec6\u80de\u76f8\u6bd4\uff0c\u9057\u4f20\u63a7\u5236\u7684hFTH-Mag\u6444\u53d6\u548c\u6eb6\u9176\u4f53\u8fd0\u8f93\u5230Tim-2\u8fc7\u8868\u8fbe\u7ec6\u80de\u4e2d\u4ea7\u751f\u4e0d\u540c\u7684OA-\u5bf9\u6bd4\uff08\u7eff\u8272\uff09\u548c\u589e\u5f3a\u7684THG\u5bf9\u6bd4\uff08\u7070\u8272\u5230\u7ea2\u8272\uff09<\/p>\n

B\uff09\u7531\u4e8e\u78c1\u6027\u94c1\u86cb\u767d\u6444\u53d6\uff08\u7eff\u8272\uff09\u800c\u4ea7\u751f\u5f3aOA\u4fe1\u53f7\u7684\u7ec6\u80de\u5728OA\u6fc0\u5149\u529f\u7387\u589e\u52a0\u7ea615\u500d\u65f6\u53ef\u4ee5\u88ab\u7279\u5f02\u6027\u5730\u6d88\u878d<\/p>\n

\u56fe3 \u78c1\u70ed\u7597\u8bf1\u5bfc\u7ec6\u80de\u6d88\u878d<\/strong><\/p>\n

\"\"<\/p>\n

A\uff09\u8fc7\u8868\u8fbeTim-2\u5e76\u8f7d\u6709hFTH-Mag\uff08\u84dd\u8272\uff09\u7684\u7ec6\u80de\u53ef\u4ee5\u901a\u8fc7\u7528\u632f\u8361\u78c1\u573a\u8fdb\u884cRF\u5904\u7406\u6765\u6d88\u878d<\/p>\n

B\uff09\u6eb6\u9176\u4f53\u86cb\u767d\u9176\u7ec4\u7ec7\u86cb\u767d\u9176B\u7279\u5f02\u6027\u7684\u6291\u5236\u5242E64d\u963b\u6b62\u4e86\u8f7d\u6709hFTH-Mag\u7684\u7a33\u5b9aTim-2\u7ec6\u80de\u4e2dRF\u8bf1\u5bfc\u7684\u7ec6\u80de\u6b7b\u4ea1<\/p>\n

C\uff09\u4eceTim-2\u8868\u8fbe\u7ec6\u80de\u4e2d\u5206\u79bb\u8d1f\u8f7d\u6709hFTH-Mag\uff08lyso-hFTH-Mag\uff09\u7684\u6eb6\u9176\u4f53<\/p>\n

\u3010\u5c0f\u7ed3\u3011<\/strong><\/p>\n

\u8be5\u5de5\u4f5c\u5728\u57fa\u56e0\u63a7\u5236\u4e0b\u5f00\u53d1\u4e86\u4e00\u79cd\u7528\u4e8e\u751f\u7269\u5408\u6210\u7eb3\u7c73\u7c92\u5b50\u6444\u53d6\u7684\u534a\u9057\u4f20\u7cfb\u7edf\uff0c\u8be5\u7cfb\u7edf\u80fd\u591f\u901a\u8fc7THG\u663e\u5fae\u955c\u4ee5\u53caOA\u548cMR\u6210\u50cf\u5b9e\u73b0\u591a\u6a21\u5f0f\u548c\u591a\u5c3a\u5ea6\u68c0\u6d4b\u3002\u8be5\u57fa\u56e0\u63a7\u5236\u7cfb\u7edf\u8fdb\u4e00\u6b65\u63d0\u4f9b\u4e86\u901a\u8fc7\u78c1\u68af\u5ea6\u7684\u7ec6\u80de\u64cd\u4f5c\u548c\u901a\u8fc7\u5149\u70e7\u8680\u6216\u5c40\u90e8\u78c1\u70ed\u7597\u7684\u7ec6\u80de\u6d88\u878d\u3002\u8be5\u8fdb\u4e00\u6b65\u7a81\u51fa\u4e86\u5229\u7528\u7eb3\u7c73\u7ed3\u6784\u4e0e\u7ec6\u80de\u9694\u5ba4\u7684\u7279\u5f02\u6027\u76f8\u4e92\u4f5c\u7528\uff0c\u8fd9\u4e9b\u7cfb\u7edf\u901a\u8fc7\u5c40\u90e8\u6539\u53d8\u7eb3\u7c73\u9897\u7c92\u7279\u6027\u63d0\u4f9b\u9ad8\u7a7a\u95f4\u7cbe\u786e\u5ea6\u3002<\/p>\n

\u6587\u732e\u94fe\u63a5\uff1a<\/strong>Genetically Controlled Lysosomal Entrapment of Superparamagnetic Ferritin for Multimodal and Multiscale Imaging and Actuation with Low Tissue Attenuation<\/a>\uff08Adv. Funct. Mater.,2018,DOI:10.1002\/adfm.201706793\uff09<\/p>\n

\u672c\u6587\u7531\u6750\u6599\u4eba\u751f\u7269\u6750\u6599\u7ec4Allen\u4f9b\u7a3f\uff0c\u6750\u6599\u725b\u6574\u7406\u7f16\u8f91\u3002<\/p>\n

\u6750\u6599\u725b\u7f51\u4e13\u6ce8\u4e8e\u8ddf\u8e2a\u6750\u6599\u9886\u57df\u79d1\u6280\u53ca\u884c\u4e1a\u8fdb\u5c55\uff0c\u8fd9\u91cc\u6c47\u96c6\u4e86\u5404\u5927\u9ad8\u6821\u7855\u535a\u751f\u3001\u4e00\u7ebf\u79d1\u7814\u4eba\u5458\u4ee5\u53ca\u884c\u4e1a\u4ece\u4e1a\u8005\uff0c\u5982\u679c\u60a8\u5bf9\u4e8e\u8ddf\u8e2a\u6750\u6599\u9886\u57df\u79d1\u6280\u8fdb\u5c55\uff0c\u89e3\u8bfb\u9ad8\u6c34\u5e73\u6587\u7ae0\u6216\u662f\u8bc4\u8ff0\u884c\u4e1a\u6709\u5174\u8da3\uff0c\u70b9\u6211\u52a0\u5165\u7f16\u8f91\u90e8\u5927\u5bb6\u5ead<\/a>\u3002<\/p>\n

\u6b22\u8fce\u5927\u5bb6\u5230\u6750\u6599\u4eba\u5ba3\u4f20\u79d1\u6280\u6210\u679c\u5e76\u5bf9\u6587\u732e\u8fdb\u884c\u6df1\u5165\u89e3\u8bfb\uff0c\u6295\u7a3f\u90ae\u7bb1tougao@cailiaoren.com\u3002<\/p>\n

\u6295\u7a3f\u4ee5\u53ca\u5185\u5bb9\u5408\u4f5c\u53ef\u52a0\u7f16\u8f91\u5fae\u4fe1\uff1aRDD-2011-CHERISH\uff0c\u4efb\u4e39\u4e39\uff0c\u6211\u4eec\u4f1a\u9080\u8bf7\u5404\u4f4d\u8001\u5e08\u52a0\u5165\u4e13\u5bb6\u7fa4\u3002
\n <\/b><\/strong><\/p>\n

\u6750\u6599\u6d4b\u8bd5\uff0c\u6570\u636e\u5206\u6790\uff0c\u4e0a<\/strong>\u6d4b\u8bd5\u8c37<\/strong><\/a>\uff01<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"

\u3010\u5f15\u8a00\u3011 \u5206\u5b50\u6210\u50cf\u548c\u81f4\u52a8\u65b9\u6cd5\u5bf9\u4e8e\u7ec6\u80de\u7f51\u7edc\u7684\u529f\u80fd\u5206\u79bb\u662f\u6709\u4ef7\u503c\u7684\uff0c\u7279\u522b\u662f\u5982\u679c\u5b83\u4eec\u63d0\u4f9b\u6df1\u5ea6\u7ec4\u7ec7\u7a7f\u900f\u5e76\u4e14\u4e0e\u5b8c\u6574\u6a21\u578b\u7cfb\u7edf\u4e2d\u7684\u7eb5\u5411\u7814\u7a76\u517c\u5bb9\u3002\u6b64\u5916\uff0c\u5bf9\u5206\u5b50\u4f20\u611f\u5668\u548c\u81f4\u52a8\u5668\u7684\u8868\u8fbe…<\/p>\n","protected":false},"author":349,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[215],"tags":[2994],"class_list":["post-132179","post","type-post","status-publish","format-standard","hentry","category-jiedu","tag-2994"],"_links":{"self":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts\/132179"}],"collection":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/users\/349"}],"replies":[{"embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=132179"}],"version-history":[{"count":4,"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts\/132179\/revisions"}],"predecessor-version":[{"id":132348,"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts\/132179\/revisions\/132348"}],"wp:attachment":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=132179"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=132179"},{"taxonomy":"post_tag","embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=132179"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}