{"id":128676,"date":"2018-03-09T06:30:36","date_gmt":"2018-03-08T22:30:36","guid":{"rendered":"\/\/m.iemloyee.com\/?p=128676"},"modified":"2018-03-07T22:05:08","modified_gmt":"2018-03-07T14:05:08","slug":"adv-funct-mater-%e5%b0%81%e9%9d%a2%ef%bc%9a%e8%82%bf%e7%98%a4%e7%89%b9%e5%bc%82%e6%80%a7%e8%87%aa%e9%99%8d%e8%a7%a3%e7%ba%b3%e7%b1%b3%e5%87%9d%e8%83%b6%e4%bd%9c%e4%b8%ba%e6%8a%97%e8%82%bf%e7%98%a4","status":"publish","type":"post","link":"\/\/m.iemloyee.com\/?p=128676","title":{"rendered":"Adv. Funct. Mater.\u5c01\u9762\uff1a\u80bf\u7624\u7279\u5f02\u6027\u81ea\u964d\u89e3\u7eb3\u7c73\u51dd\u80f6\u4f5c\u4e3a\u6297\u80bf\u7624\u86cb\u767d\u7cfb\u7edf\u9012\u9001\u7684\u6f5c\u5728\u8f7d\u4f53"},"content":{"rendered":"

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f\uff09\u4e0d\u540c\u5236\u5242\u9996\u6b21\u7ed9\u836f30\u5929\u540e\uff0c\u7528Ki-67\u6297\u4f53\u67d3\u8272\u7684\u80bf\u7624\u56fe\u50cf\uff08\u6bd4\u4f8b\u5c3a\u4e3a100 \u00b5m\uff09\u3002<\/p>\n

\u3010\u5c0f\u7ed3\u3011<\/strong><\/p>\n

\u603b\u4e4b\uff0c\u8be5\u7814\u7a76\u8bbe\u8ba1\u4e86\u4e00\u79cd\u80bf\u7624\u7279\u5f02\u6027\u9178\u54cd\u5e94\u7684\u81ea\u964d\u89e3\u7eb3\u7c73\u51dd\u80f6\uff0c\u7528\u4e8e\u9ad8\u6548\u7684\u86cb\u767d\u8d28\u8f93\u9001\u548c\u764c\u75c7\u6cbb\u7597\u3002\u57fa\u4e8eHA\u7684\u534f\u540c\u4ea4\u8054\u7684\u7eb3\u7c73\u51dd\u80f6\u5177\u6709\u5185\u90e8\u6c34\u5408\u7f51\u7edc\u7ed3\u6784\uff0c\u5bf9\u4e8e\u4e0d\u540c\u5206\u5b50\u91cf\uff08MW\uff09\u548c\u7b49\u7535\u70b9\uff08pI\uff09\u7684\u86cb\u767d\u8d28\u5747\u5177\u6709\u9ad8\u8d1f\u8f7d\u80fd\u529b\uff0c\u800c\u4e14\u5177\u6709\u826f\u597d\u7684\u8840\u6d46\u7a33\u5b9a\u6027\u3002\u7eb3\u7c73\u51dd\u80f6\u4e2d\u5f15\u5165\u9178\u6d3b\u5316\u7684aHAase\uff0c\u53ef\u5b9e\u73b0\u6709\u6548\u7684\u7ea7\u8054\u86cb\u767d\u9012\u9001\uff1a\u80bf\u7624\u7ec4\u7ec7\u7684\u6df1\u5c42\u6e17\u900f\u3001\u7ec6\u80de\u6444\u53d6\u7684\u589e\u52a0\u3001\u7ec6\u80de\u5185\u86cb\u767d\u8d28\u7684\u53ef\u63a7\u91ca\u653e\u548c\u8f7d\u4f53\u6750\u6599\u7684\u6709\u6548\u964d\u89e3\u3002\u8fd9\u4e00\u7b56\u7565\u5c06\u4fc3\u8fdb\u5177\u6709\u7a0b\u5e8f\u6027\u81ea\u9a71\u52a8\u964d\u89e3\u6027\u7684\u7eb3\u7c73\u8f7d\u4f53\u7684\u5f00\u53d1\uff0c\u4e3a\u86cb\u767d\u836f\u7269\u7684\u9012\u9001\u548c\u80bf\u7624\u6cbb\u7597\u63d0\u4f9b\u65b0\u6280\u672f\u548c\u65b0\u624b\u6bb5\u3002<\/p>\n

\u6587\u732e\u94fe\u63a5\uff1a<\/strong>Tumor-Specific Self-Degradable Nanogels as Potential Carriers for Systemic Delivery of Anticancer Proteins<\/a>(Adv. Funct. Mater.,2018,DOI: 10.1002\/adfm.201707371)<\/p>\n

\u901a\u8baf\u4f5c\u8005\u7b80\u4ecb\uff1a<\/strong>\u83ab\u7136\uff0c\u4e2d\u56fd\u836f\u79d1\u5927\u5b66\u6559\u6388\uff0c\u535a\u5bfc\uff0c\u4e3b\u8981\u4ece\u4e8b\u65b0\u578b\u836f\u7528\u529f\u80fd\u6750\u6599\u53ca\u5176\u6784\u5efa\u7684\u667a\u80fd\u9012\u836f\u7cfb\u7edf\u7684\u521b\u65b0\u7814\u53d1\uff0c\u7279\u522b\u81f4\u529b\u4e8e\u6297\u80bf\u7624\u836f\u7269\u7684\u7cbe\u51c6\u9012\u9001\uff0c\u7528\u4e8e\u6076\u6027\u80bf\u7624\u7684\u9ad8\u6548\u6cbb\u7597\u3002\u4ee5\u901a\u8baf\u6216\u7b2c\u4e00\u4f5c\u8005\u5728Nature Nanotechnol.\u3001Nature Commun.\u3001J. Am. Chem. Soc.\u3001Angew. Chem. Int. Ed.\u3001Adv. Mater.\u3001Nano Lett.\u3001Adv. Funct. Mater.\u7b49\u56fd\u9645\u671f\u520a\u4e0a\u53d1\u8868SCI\u8bba\u658725\u7bc7\uff0c\u5176\u4e2d\u5f71\u54cd\u56e0\u5b50>30\u7684\u8bba\u65872\u7bc7\uff0c30>\u5f71\u54cd\u56e0\u5b50>10\u7684\u8bba\u658711\u7bc7\uff0c\u4ed6\u5f151000\u4f59\u6b21\uff0c\u5165\u9009ESI\u9ad8\u88ab\u5f15\u8bba\u65873\u7bc7\u3002\u7814\u7a76\u6210\u679c\u88abNature\u3001Nature Reviews Cancer\u3001Nature Reviews Drug Discovery\u3001F1000 Prime\u7b49\u56fd\u9645\u671f\u520a\u548c\u65b0\u95fb\u5a92\u4f53\u4eae\u70b9\u62a5\u9053\u3002\u66fe\u83b7\u4e2d\u56fd\u836f\u5b66\u4f1a\u4ee5\u5cad\u751f\u7269\u533b\u836f\u9752\u5e74\u5956\u3001\u4e2d\u56fd\u836f\u5b66\u4f1a\u9752\u5e74\u836f\u5242\u5b66\u5956\u3002<\/p>\n

\u611f\u8c22\u672c\u6587\u901a\u8baf\u4f5c\u8005\u4e2d\u56fd\u836f\u79d1\u5927\u5b66\u83ab\u7136\u6559\u6388\u5bf9\u672c\u6587\u7684\u65a7\u6b63\uff01<\/strong><\/p>\n

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\u6b22\u8fce\u5927\u5bb6\u5230\u6750\u6599\u4eba\u5ba3\u4f20\u79d1\u6280\u6210\u679c\u5e76\u5bf9\u6587\u732e\u8fdb\u884c\u6df1\u5165\u89e3\u8bfb\uff0c\u6295\u7a3f\u90ae\u7bb1tougao@cailiaoren.com\u3002<\/p>\n

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