{"id":128565,"date":"2018-03-07T06:30:46","date_gmt":"2018-03-06T22:30:46","guid":{"rendered":"\/\/m.iemloyee.com\/?p=128565"},"modified":"2018-03-23T20:56:01","modified_gmt":"2018-03-23T12:56:01","slug":"adv-mater-adv-funct-mater-%e7%ad%89%e7%94%9f%e7%89%a9%e6%9d%90%e6%96%99%e6%9c%80%e6%96%b0%e7%a0%94%e7%a9%b6%e6%88%90%e6%9e%9c%e7%b2%be%e9%80%892018%e5%b9%b42%e6%9c%88%e5%88%8a","status":"publish","type":"post","link":"\/\/m.iemloyee.com\/?p=128565","title":{"rendered":"Adv. Mater.\/Adv. Funct. Mater.\u7b49\u751f\u7269\u6750\u6599\u6700\u65b0\u7814\u7a76\u6210\u679c\u7cbe\u9009|2018\u5e742\u6708\u520a"},"content":{"rendered":"<p>\u6750\u6599\u4eba\u63a8\u51fa\u751f\u7269\u6750\u6599\u6210\u679c\u6c47\u7f16\uff08\u6708\u520a\uff09\uff0c\u62a5\u9053\u8fd1\u671f\u751f\u7269\u6750\u6599\u76f8\u5173\u91cd\u5927\u6210\u679c\u3002<\/p>\n<p><strong>1. Adv. Mater.:\u7f13\u89e3\u8c37\u6c28\u9178\u8bf1\u5bfc\u7684\u5174\u594b\u6027\u6bd2\u6027\uff0c\u751f\u7269\u53ef\u964d\u89e3\u7403\u4f53\u4fdd\u62a4\u521b\u4f24\u6027\u810a\u9ad3\u635f\u4f24<\/strong><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-128567\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2018\/03\/1-7.jpg\" alt=\"\" width=\"600\" height=\"510\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2018\/03\/1-7.jpg 600w, \/\/m.iemloyee.com\/wp-content\/uploads\/2018\/03\/1-7-300x255.jpg 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/p>\n<p>\u8fd1\u65e5\uff0c<strong>\u5357\u4eac\u533b\u79d1\u5927\u5b66\u7b2c\u4e00\u9644\u5c5e\u533b\u9662Fan Jin\u3001\u6bb7\u56fd\u52c7\u548c\u82ac\u5170\u8d6b\u5c14\u8f9b\u57fa\u5927\u5b66H\u00e9lder A. Santos\uff08\u5171\u540c\u901a\u8baf\u4f5c\u8005\uff09<\/strong>\u7b49\u4eba\u79ef\u6781\u63a2\u7d22\u6cbb\u7597\u810a\u9ad3\u635f\u4f24\u7684\u65b0\u7597\u6cd5\uff0c\u901a\u8fc7\u4fee\u9970\u8461\u805a\u7cd6\u7684\u90bb\u4f4d\u4e8c\u9187\uff0c\u83b7\u5f97\u7684\u751f\u7269\u53ef\u964d\u89e3\u805a\u5408\u7269\u7f29\u919b\u5316\u8461\u805a\u7cd6\uff08AcDX\uff09\u88ab\u8bc1\u5b9e\u53ef\u4ee5\u4fdd\u62a4\u5916\u4f24\u6027\u810a\u9ad3\u3002\u901a\u8fc7\u5fae\u6d41\u4f53\u6280\u672f\u5c06AcDX\u914d\u5236\u6210\u5fae\u7403\u4f53\uff08\u76f4\u5f84\u22487.2\u03bcm\uff09\uff0c\u9798\u5185\u6ce8\u5c04AcDX\u5fae\u7403\u53ef\u6709\u6548\u51cf\u5c11\u635f\u4f24\u810a\u9ad3\u7684\u521b\u4f24\u6027\u635f\u4f24\u4f53\u79ef\u548c\u708e\u75c7\u53cd\u5e94\uff0c\u4fdd\u62a4\u810a\u9ad3\u795e\u7ecf\u5143\u514d\u4e8e\u51cb\u4ea1\uff0c\u6700\u7ec8\u6062\u590d\u635f\u4f24\u5927\u9f20\u7684\u8fd0\u52a8\u529f\u80fd\u3002AcDX\u5fae\u7403\u4f53\u7684\u795e\u7ecf\u4fdd\u62a4\u7279\u5f81\u662f\u901a\u8fc7\u9694\u79bb\u8111\u810a\u6db2\u4e2d\u7684\u8c37\u6c28\u9178\u76d0\u548c\u9499\u79bb\u5b50\u5b9e\u73b0\u7684\u3002\u8c37\u6c28\u9178\u548c\u9499\u79bb\u5b50\u7684\u6e05\u9664\u51cf\u5c11\u4e86\u9499\u79bb\u5b50\u6d41\u5165\u795e\u7ecf\u5143\uff0c\u5e76\u6291\u5236\u6d3b\u6027\u6c27\u7684\u5f62\u6210\u3002\u56e0\u6b64\uff0cAcDX\u5fae\u7403\u51cf\u5f31\u4e86\u4fc3\u51cb\u4ea1\u86cb\u767d\u3001\u9499\u86cb\u767d\u9176\u548cBax\u7684\u8868\u8fbe\uff0c\u5e76\u589e\u5f3a\u6297\u51cb\u4ea1\u86cb\u767dBcl-2\u7684\u8868\u8fbe\u3002\u603b\u4f53\u800c\u8a00\uff0cAcDX\u5fae\u7403\u901a\u8fc7\u7f13\u89e3\u8c37\u6c28\u9178\u8bf1\u5bfc\u7684\u5174\u594b\u6027\u6bd2\u6027\u4fdd\u62a4\u521b\u4f24\u6027\u810a\u9ad3\u635f\u4f24\u3002\u8fd9\u9879\u7814\u7a76\u4e3a\u5e94\u7528\u795e\u7ecf\u4fdd\u62a4\u6027AcDX\u6cbb\u7597\u4e25\u91cd\u795e\u7ecf\u75be\u75c5\u5f00\u8f9f\u4e86\u65b0\u9014\u5f84\u3002<\/p>\n<p>\u6587\u732e\u94fe\u63a5\uff1a<a href=\"http:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/adma.201706032\/full\" target=\"_blank\" rel=\"noopener\">Biodegradable Spheres Protect Traumatically Injured Spinal Cord by Alleviating the Glutamate-Induced Excitotoxicity <\/a>\uff08Adv. Mater.\uff0c2018\uff0cDOI: 10.1002\/adma.201706032\uff09<\/p>\n<p><strong>2. Adv. Mater.:\u901a\u8fc73D NIR-II\u5206\u5b50\u6210\u50cf\u6280\u672f\u533a\u5206\u9776\u5411\u5668\u5b98\u4e0e\u9ad8\u6027\u80fdNIR-II\u751f\u7269\u7f00\u5408\u7269<\/strong><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-128568\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2018\/03\/2-8.jpg\" alt=\"\" width=\"600\" height=\"495\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2018\/03\/2-8.jpg 600w, \/\/m.iemloyee.com\/wp-content\/uploads\/2018\/03\/2-8-300x248.jpg 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/p>\n<p>\u7b2c\u4e8c\u4e2a\u8fd1\u7ea2\u5916\uff08NIR-II\uff09\u533a\u57df\uff081000-1700 nm\uff09\u7684\u6563\u5c04\u5927\u5927\u51cf\u5c11\uff0c\u4e3a\u751f\u7269\u6210\u50cf\u7814\u7a76\u5f00\u8f9f\u4e86\u8bb8\u591a\u65b0\u9014\u5f84\u3002\u4f46NIR-II\u8367\u5149\u6210\u50cf\u4e3b\u8981\u901a\u8fc7\u4f7f\u7528\u975e\u5b9a\u5411\u8367\u5149\u56e2\u6216\u5e7f\u89d2\u6210\u50cf\u88c5\u7f6e\uff0c\u9650\u5236\u4e86\u4fe1\u53f7\u80cc\u666f\u6bd4\u548c\u6210\u50cf\u7a7f\u900f\u6df1\u5ea6\u3002\u8fd1\u65e5\uff0c<strong>\u7f8e\u56fd\u65af\u5766\u798f\u5927\u5b66\u6234\u5b8f\u6770\u9662\u58eb\u3001Aaron J. Hsueh\u548c\u5357\u65b9\u79d1\u6280\u5927\u5b66\u6881\u6c38\u6654\u6559\u6388\uff08\u5171\u540c\u901a\u8baf\u4f5c\u8005\uff09<\/strong>\u7b49\u4eba\u65b0\u5f00\u53d1\u7684\u9ad8\u6027\u80fdNIR-II\u751f\u7269\u7f00\u5408\u7269\u53ef\u4ee5\u9ad8\u8d28\u91cf\u5730\u5bf9\u6d3b\u4f53\u5185\u7279\u5b9a\u5668\u5b98\u8fdb\u884c\u6709\u9488\u5bf9\u6027\u7684\u6210\u50cf\u3002\u7ed3\u5408\u81ea\u5236\u7684NIR-II\u5171\u7126\u8bbe\u7f6e\uff0c\u65e0\u9700\u7269\u7406\u5207\u7247\u6216\u6e05\u9664\u5904\u7406\uff0c\u589e\u5f3a\u6210\u50cf\u6280\u672f\u53ef\u5b9e\u73b0900\u03bcm\u6df1\u76843D\u5668\u5b98\u6210\u50cf\u3002\u5728\u4f20\u7edf\u53ef\u89c1NIR-I\u8303\u56f4\u5916\uff0c\u7814\u7a76\u4e3a\u590d\u6742\u751f\u7269\u7cfb\u7edf\u5f00\u8f9f\u4e86\u66f4\u591a\u4e14\u66f4\u6df1\u7684\u975e\u91cd\u53e0\u5206\u5b50\u6210\u50cf\u901a\u9053\uff0c\u589e\u52a0\u4e86\u57fa\u4e8e\u8367\u5149\u6280\u672f\u7684\u6210\u50cf\u591a\u6837\u6027\u548c\u5206\u5b50\u6210\u50cf\u80fd\u529b\u3002<\/p>\n<p>\u6587\u732e\u94fe\u63a5\uff1a<a href=\"http:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/adma.201705799\/full\" target=\"_blank\" rel=\"noopener\">3D NIR-II Molecular Imaging Distinguishes Targeted Organs with High-Performance NIR-II Bioconjugates<\/a>\uff08Adv. Mater.\uff0c2018\uff0cDOI: 10.1002\/adma.201705799\uff09<\/p>\n<p><strong>3. Adv. Funct. Mater.:\u7528\u591a\u529f\u80fd\u8fd1\u7ea2\u5916\u805a\u5408\u7269\u70b9\u5feb\u901f\u51c6\u786e\u5730\u663e\u793a\u6dcb\u5df4\u7ed3\u8f6c\u79fb<\/strong><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-128569\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2018\/03\/3-4-1.jpg\" alt=\"\" width=\"600\" height=\"725\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2018\/03\/3-4-1.jpg 600w, \/\/m.iemloyee.com\/wp-content\/uploads\/2018\/03\/3-4-1-248x300.jpg 248w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/p>\n<p>\u5411\u533a\u57df\u6dcb\u5df4\u7ed3\u8f6c\u79fb\u662f\u764c\u75c7\u8fdb\u5c55\u7684\u91cd\u8981\u9884\u540e\u6307\u6807\uff0c\u80fd\u591f\u5feb\u901f\u51c6\u786e\u8bca\u65ad\u6dcb\u5df4\u7ed3\u8f6c\u79fb\u76f8\u5f53\u91cd\u8981\u30022018\u5e742\u670815\u65e5\uff0c<strong>\u4e0a\u6d77\u4ea4\u901a\u5927\u5b66\u718a\u4e3d\u7434\uff08\u901a\u8baf\u4f5c\u8005\uff09<\/strong>\u7b49\u4eba\u901a\u8fc7\u4e00\u9505\u518d\u6c89\u6dc0\u6cd5\u5236\u5907\u8367\u5149\u805a\u5408\u7269\u70b9\uff0c\u7528\u4e8e\u4f53\u5185NIR \/ PA \/ MR\u6210\u50cf\u548c\u5149\u52a8\u529b\u6cbb\u7597\u3002\u5171\u7126\u663e\u5fae\u955c\u5206\u6790\u548c\u6d41\u5f0f\u7ec6\u80de\u672f\u8868\u660e\uff0c\u5177\u6709\u53f6\u9178\u53d7\u4f53\u8868\u8fbe\u7684\u80ba\u7c98\u819c\u4e0a\u76ae\u7ec6\u80de\u764cNCI-H292\u5bf9\u53f6\u9178\u5b98\u80fd\u805a\u5408\u7269\u70b9\u5448\u9633\u6027\u3002\u4f53\u5185\u548c\u4f53\u5916NIR\u6210\u50cf\u7ed3\u679c\u8bc1\u5b9e\uff0c\u805a\u5408\u7269\u70b9\u5728\u6ce8\u5c04\u540e1\u5c0f\u65f6\u80fd\u591f\u6709\u6548\u533a\u5206\u8f6c\u79fb\u6dcb\u5df4\u7ed3\u548c\u6b63\u5e38\u6dcb\u5df4\u7ed3\uff0c\u5728\u5b9e\u65f6\u6210\u50cf\u624b\u672f\u4e2d\u6709\u6f5c\u5728\u7684\u5e94\u7528\u524d\u666f\u3002\u6b64\u5916\uff0c\u4f53\u5185MR\u548cPA\u6210\u50cf\u8bc1\u5b9e\u8f6c\u79fb\u6dcb\u5df4\u7ed3\u4e2d\u805a\u5408\u7269\u70b9\u7684MR\u548cPA\u4fe1\u53f7\u589e\u5f3a\u3002\u4e0eNIR\u6210\u50cf\u76f8\u6bd4\uff0cMR\u548cPA\u6210\u50cf\u663e\u793a\u9ad8\u5206\u8fa8\u7387\uff0c\u5e76\u4e14\u89c2\u5bdf\u5230\u5c0f\u9f20\u4f53\u5185\u80bf\u7624\u4fa7\u7684\u6dcb\u5df4\u7ed3\u80bf\u5927\u3002\u8fd9\u9879\u7814\u7a76\u63d0\u4f9b\u4e86\u4e00\u4e2a\u72ec\u7279\u7684\u65b9\u6cd5\uff0c\u4f7f\u7528\u591a\u529f\u80fd\u805a\u5408\u7269\u70b9\u5feb\u901f\u548c\u7cbe\u786e\u5730\u8bca\u65ad\u4f53\u5185\u6dcb\u5df4\u7ed3\u8f6c\u79fb\u3002<\/p>\n<p>\u6587\u732e\u94fe\u63a5\uff1a<a href=\"http:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/adfm.201707174\/full\" target=\"_blank\" rel=\"noopener\">Fast and Accurate Imaging of Lymph Node Metastasis with Multifunctional Near-Infrared Polymer Dots<\/a>\uff08Adv. Funct. Mater.\uff0c2018\uff0cDOI: 10.1002\/adfm.201707174\uff09<\/p>\n<p><strong>4. Adv. Funct. Mater.:PpIX\u5305\u8986\u7684SPION\u7eb3\u7c73\u56e2\u7c07\uff0c\u7528\u4e8e\u78c1\u5171\u632f\u6210\u50cf\u548c\u5149\u52a8\u529b\u6cbb\u7597<\/strong><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-128570\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2018\/03\/4-5-1.jpg\" alt=\"\" width=\"600\" height=\"296\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2018\/03\/4-5-1.jpg 600w, \/\/m.iemloyee.com\/wp-content\/uploads\/2018\/03\/4-5-1-300x148.jpg 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/p>\n<p>\u5927\u89c4\u6a21\u751f\u4ea7\u7eb3\u7c73\u6cbb\u7597\u836f\u7269\u7684\u80fd\u529b\u5bf9\u4e8e\u4e34\u5e8a\u8f6c\u8bd1\u81f3\u5173\u91cd\u8981\u3002\u7136\u800c\uff0c\u5927\u591a\u6570\u57fa\u4e8e\u7eb3\u7c73\u9897\u7c92\u7684\u6cbb\u7597\u5242\u5408\u6210\u8fc7\u7a0b\u590d\u6742\u3001\u7a33\u5b9a\u6027\u4f4e\u4e14\u6210\u672c\u9ad8\u30022018\u5e742\u670815\u65e5\uff0c<strong>\u5bbe\u5915\u6cd5\u5c3c\u4e9a\u5927\u5b66\u751f\u7269\u5de5\u7a0b\u7cfbAndrew Tsourkas\u548c\u7a0b\u5fd7\u4eae\u535a\u58eb\uff08\u5171\u540c\u901a\u8baf\u4f5c\u8005\uff09<\/strong>\u7b49\u4eba\u5229\u7528\u4e00\u79cd\u7b80\u5355\u7684\u65b9\u6cd5\u5236\u5907\u591a\u529f\u80fd\u7eb3\u7c73\u7c92\u5b50\uff0c\u65e2\u53ef\u4ee5\u4f5c\u4e3a\u78c1\u5171\u632f\u6210\u50cf\u7684\u9020\u5f71\u5242\uff0c\u53c8\u53ef\u4ee5\u4f5c\u4e3a\u6cbb\u7597\u764c\u75c7\u7684\u5149\u52a8\u529b\u6cbb\u7597\u7684\u5149\u654f\u5242\u3002\u5177\u4f53\u800c\u8a00\uff0c\u7528\u5149\u654f\u5242\u539f\u535f\u5549IX\uff08PpIX\uff09\u6eb6\u89e3\u8d85\u987a\u78c1\u6027\u6c27\u5316\u94c1\u7eb3\u7c73\u9897\u7c92\uff08SPION\uff09\u7684\u5c0f\u7eb3\u7c73\u56e2\u7c07\uff0c\u4e0d\u9700\u8981\u4f7f\u7528\u4efb\u4f55\u989d\u5916\u7684\u8f7d\u4f53\u6750\u6599\u3002\u8fd9\u4e9b\u7eb3\u7c73\u56e2\u7c07\u5177\u6709\u9ad8PpIX\u8d1f\u8f7d\u6548\u7387\uff0c\u627f\u8f7d\u80fd\u529b\u9ad8\uff0c\u7a33\u5b9a\u6027\u597d\uff0c\u9002\u5408\u5927\u89c4\u6a21\u7684\u751f\u4ea7\uff0c\u5728\u4e34\u5e8a\u8f6c\u8bd1\u7684\u7eb3\u7c73\u6cbb\u7597\u836f\u7269\u4e2d\u6709\u6781\u5927\u7684\u5e94\u7528\u524d\u666f\u3002<\/p>\n<p>\u6587\u732e\u94fe\u63a5\uff1a<a href=\"http:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/adfm.201707030\/full\" target=\"_blank\" rel=\"noopener\">Protoporphyrin IX (PpIX)-Coated Superparamagnetic Iron Oxide Nanoparticle (SPION) Nanoclusters for Magnetic Resonance Imaging and Photodynamic Therapy<\/a>\uff08Adv. Funct. Mater.\uff0c2018\uff0cDOI: 10.1002\/adfm.201707030\uff09<\/p>\n<p><strong>5.Adv. Funct. Mater.: \u7528\u4e8e\u86cb\u767d\u8d28\u8f93\u9001\u7684\u7eb3\u7c73\u5c3a\u5bf8Zr-MOFs<\/strong><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-128571\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2018\/03\/5-6-1.jpg\" alt=\"\" width=\"600\" height=\"316\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2018\/03\/5-6-1.jpg 600w, \/\/m.iemloyee.com\/wp-content\/uploads\/2018\/03\/5-6-1-300x158.jpg 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/p>\n<p>\u5728\u53ef\u8c03\u8282\u7c92\u5f84\u7684\u539f\u59cb\u5fae\u5b54\u91d1\u5c5e\u6709\u673a\u9aa8\u67b6\uff08MOF\uff09\u4e2d\u5f15\u5165\u5927\u5b54\uff0c\u53ef\u5f00\u53d1\u5b83\u4eec\u5728\u7ec6\u80de\u5185\u9012\u9001\u819c\u4e0d\u53ef\u6e17\u900f\u86cb\u767d\u8d28\u7684\u6f5c\u5728\u5e94\u7528\u30022018\u5e742\u670814\u65e5\uff0c<strong>\u534e\u4e1c\u7406\u5de5\u5927\u5b66\u987e\u91d1\u697c\u6559\u6388\u548c\u4e0a\u6d77\u4ea4\u901a\u5927\u5b66\u533b\u5b66\u9662\u6881\u963f\u5a1f\uff08\u5171\u540c\u901a\u8baf\u4f5c\u8005\uff09<\/strong>\u7b49\u4eba\u5f00\u53d1\u4e86\u4e00\u5143\u7fa7\u9178\uff08MA\uff09\u548c\u6709\u673a\u78b1\u8c03\u5236\u7b56\u7565\u6765\u5408\u6210\u5206\u7ea7\u591a\u5b54UiO-66\u7eb3\u7c73\u9897\u7c92\u3002\u4f7f\u7528\u5341\u4e8c\u70f7\u9178\u7684MA\u6765\u63a7\u5236\u5b54\u5f84\uff0c\u800c\u4e09\u7532\u80fa\uff08TEA\uff09\u5728\u8c03\u8282\u7ed3\u6676\u6210\u6838\u7c92\u5ea6\u65b9\u9762\u8d77\u5173\u952e\u4f5c\u7528\u3002\u4e0e\u5fae\u5b54UiO-66\u76f8\u6bd4\uff0c\u7ec6\u80de\u8272\u7d20c\u6a21\u578b\u86cb\u767d\uff08Cyt c\uff09\u53ef\u4ee5\u6709\u6548\u5730\u88c5\u8f7d\u5230\u4ecb\u5b54MOFs\uff08mesoMOFs\uff09\u4e2d\u3002\u5177\u670990nm\u7c92\u5f84\u7684mesoMOFs\u53ef\u4ee5\u4ee5\u6700\u9ad8\u6548\u7387\u88ab\u80de\u541e\u5165\u6d3b\u7ec6\u80de\u4e2d\u3002\u8fd9\u4e9b\u7a81\u51fa\u7684\u4f18\u70b9\u4f7f\u76ee\u524d\u7684mesoMOFs\u4e0d\u4ec5\u80fd\u5c55\u73b0Cyt c\u7684\u9ad8\u6548\u5305\u88f9\uff0c\u800c\u4e14\u8fd8\u4fc3\u8fdb\u86cb\u767d\u8d28\u8fdb\u5165\u80de\u8d28\u6eb6\u80f6\u548c\u968f\u540e\u7684\u5185\u4f53\u9003\u9038\u3002\u9274\u4e8e\u5353\u8d8a\u7684\u5316\u5b66\u7a33\u5b9a\u6027\u3001\u7b49\u7ea7\u591a\u5b54\u7ed3\u6784\u4ee5\u53ca\u53ef\u8c03\u8282\u7684\u7c92\u5f84\uff0cmesoUiO-66\u7eb3\u7c73\u7c92\u5b50\u53ef\u80fd\u4e3a\u5404\u79cd\u751f\u7269\u533b\u5b66\u5e94\u7528\u63d0\u4f9b\u4e86\u4e00\u4e2a\u6709\u524d\u9014\u7684\u5e73\u53f0\u3002<\/p>\n<p>\u6587\u732e\u94fe\u63a5\uff1a<a href=\"http:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/adfm.201707356\/full\" target=\"_blank\" rel=\"noopener\">Nanoscale Zr-Based MOFs with Tailorable Size and Introduced Mesopore for Protein Delivery<\/a>\uff08Adv. Funct. Mater.\uff0c2018\uff0cDOI: 10.1002\/adfm.201707356\uff09<\/p>\n<p><strong>6. Nano Lett.:\u80bd\u529f\u80fd\u5316\u76f8\u53d8\u7eb3\u7c73\u7c92\u5b50\u7684\u4f4e\u5f3a\u5ea6\u805a\u7126\u8d85\u58f0\u8f85\u52a9\u80bf\u7624\u6210\u50cf\u548c\u6cbb\u7597<\/strong><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-128572\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2018\/03\/6-9.jpg\" alt=\"\" width=\"600\" height=\"138\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2018\/03\/6-9.jpg 600w, \/\/m.iemloyee.com\/wp-content\/uploads\/2018\/03\/6-9-300x69.jpg 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/p>\n<p>2018\u5e742\u67088\u65e5\uff0c<strong>\u91cd\u5e86\u533b\u79d1\u5927\u5b66\u9644\u5c5e\u7b2c\u4e8c\u533b\u9662\u8d85\u58f0\u79d1\u4efb\u5efa\u4e3d\uff08\u901a\u8baf\u4f5c\u8005\uff09<\/strong>\u7b49\u4eba\u4e3a\u4f4e\u5f3a\u5ea6\u805a\u7126\u8d85\u58f0\uff08LIFU\uff09\u8f85\u52a9\u80bf\u7624\u8d85\u58f0\u5206\u5b50\u6210\u50cf\u548c\u7cbe\u786e\u6cbb\u7597\uff0c\u7814\u53d1\u4e86\u65b0\u578b\u80bf\u7624\u5f52\u5de2\u7a7f\u900f\u80bd\u529f\u80fd\u5316\u836f\u7269\u8d1f\u8f7d\u76f8\u53d8\u7eb3\u7c73\u9897\u7c92\uff08tLyP-1-10-HCPT-PFP NPs\uff09\u3002\u7eb3\u7c73\u7ea7\u7c92\u5f84\u7684tLyP-1-10-HCPT-PFP NPs\u53ef\u901a\u8fc7\u80bf\u7624\u8840\u7ba1\u5185\u76ae\u7ec6\u80de\u95f4\u9699\u3002\u901a\u8fc7\u9776\u5411\u548c\u7a7f\u900f\u6548\u7387\u7684tLyP-1\u80bd\u8bf1\u5bfc\uff0ctLyP-1-10-HCPT-PFP NPs\u53ef\u4ee5\u589e\u52a0\u80bf\u7624\u7684\u79ef\u805a\uff0c\u6df1\u5165\u8840\u7ba1\u5916\u80bf\u7624\u7ec4\u7ec7\uff0c\u7a7f\u900f\u7ec6\u80de\u5916\u57fa\u8d28\u548c\u7ec6\u80de\u819c\u8fdb\u5165\u7ec6\u80de\u8d28\u3002\u5728LIFU\u7684\u534f\u52a9\u4e0b\uff0ctLyP-1-10-HCPT-PFP\u7eb3\u7c73\u9897\u7c92\u53ef\u4ee5\u76f8\u53d8\u6210\u5fae\u6ce1\uff0c\u5e76\u589e\u5f3a\u80bf\u7624\u8d85\u58f0\u5206\u5b50\u6210\u50cf\u5bf9\u80bf\u7624\u7684\u8bca\u65ad\u3002\u6b64\u5916\uff0c\u5728LIFU\u8fdb\u4e00\u6b65\u7167\u5c04\u540e\uff0c\u58f0\u6ce2\u6db2\u6ef4\u6c7d\u5316\u5728\u7ec6\u80de\u5185\u5f15\u53d1\u201c\u7206\u70b8\u6548\u5e94\u201d\uff0c\u8d85\u58f0\u9776\u5411\u5fae\u6ce1\u7834\u574f\u548c10-HCPT\u7684\u91ca\u653e\u53ef\u5b9e\u73b0\u7269\u7406\u5316\u5b66\u534f\u540c\u6297\u80bf\u7624\u6cbb\u7597\u3002<\/p>\n<p>\u6587\u732e\u94fe\u63a5\uff1a<a href=\"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.nanolett.7b05087\" target=\"_blank\" rel=\"noopener\">Peptide-Functionalized Phase-Transformation Nanoparticles for Low Intensity Focused Ultrasound-Assisted Tumor Imaging and Therapy<\/a>\uff08Nano Lett.\uff0c2018\uff0cDOI: 10.1021\/acs.nanolett.7b05087\uff09<\/p>\n<p><strong>7. Nat. Mater.:\u7ec6\u80de\u819c\u51e0\u4f55\u4f9d\u8d56\u6027\u7684\u53d8\u5316\u76f4\u63a5\u5f15\u53d1\u5e72\u7ec6\u80de\u4fe1\u53f7\u4f20\u5bfc<\/strong><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-128573\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2018\/03\/7-2-1.jpg\" alt=\"\" width=\"600\" height=\"935\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2018\/03\/7-2-1.jpg 600w, \/\/m.iemloyee.com\/wp-content\/uploads\/2018\/03\/7-2-1-193x300.jpg 193w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/p>\n<p>\u7ec6\u80de\u7684\u5927\u5c0f\u548c\u5f62\u72b6\u4f1a\u5f71\u54cd\u7ec6\u80de\u7684\u751f\u957f\u3001\u5b58\u6d3b\u548c\u5206\u5316\u7b49\u884c\u4e3a\u6d3b\u52a8\uff0c\u56e0\u6b64\u6784\u5efa\u7ec6\u80de\u51e0\u4f55\u53ef\u4f5c\u4e3a\u7ec6\u80de\u751f\u7406\u5b66\u7684\u57fa\u672c\u8c03\u8282\u5668\u3002\u7ec6\u80de\u9aa8\u67b6\uff0c\u7279\u522b\u662f\u808c\u52a8\u7403\u86cb\u767d\u5f20\u529b\u7684\u76f8\u5173\u6548\u5e94\u5df2\u7ecf\u6709\u8fc7\u62a5\u9053\u3002\u4f46\u662f\u5c06\u7ec6\u80de\u51e0\u4f55\u5f62\u72b6\u7684\u53d8\u5316\u8f6c\u53d8\u4e3a\u7ec6\u80de\u884c\u4e3a\u53d8\u5316\u7684\u786e\u5207\u751f\u7269\u7269\u7406\u5b66\u673a\u5236\u4ecd\u672a\u5f97\u5230\u89e3\u51b3\u3002\u4f7f\u7528\u5404\u79cd\u521b\u65b0\u6750\u6599\u6280\u672f\uff0c<strong>\u82f1\u56fd\u4f26\u6566\u5e1d\u56fd\u7406\u5de5\u5b66\u9662\u751f\u7269\u533b\u5b66\u5de5\u7a0b\u7814\u7a76\u6240Molly M. Stevens\u548cSilvia Goldoni\uff08\u5171\u540c\u901a\u8baf\u4f5c\u8005\uff09<\/strong>\u7b49\u4eba\u8bc1\u5b9e\u901a\u8fc7\u7ec6\u80de\u51e0\u4f55\u5b66\u4ee5\u914d\u4f53\u975e\u4f9d\u8d56\u6027\u7684\u65b9\u5f0f\uff0c\u53ef\u8c03\u8282\u7ec6\u80de\u8d28\u819c\u5185\u7684\u7eb3\u7c73\u7ed3\u6784\u548c\u8102\u8d28\u7ec4\u88c5\u3002\u7814\u7a76\u7ed3\u679c\u5bf9\u518d\u751f\u533b\u5b66\u548c\u7ec4\u7ec7\u5de5\u7a0b\u5e94\u7528\u5177\u6709\u5e7f\u6cdb\u7684\u610f\u4e49\u3002<\/p>\n<p>\u6587\u732e\u94fe\u63a5\uff1a<a href=\"https:\/\/www.nature.com\/articles\/s41563-017-0014-0\" target=\"_blank\" rel=\"noopener\">Cell-geometry-dependent changes in plasma membrane order direct stem cell signalling and fate<\/a>\uff08Nat. Mater.\uff0c2018\uff0cdoi:10.1038\/s41563-017-0014-0\uff09<\/p>\n<p><strong>8. Nat. Nanotech.\uff1a\u9488\u5bf9RNAi\u6cbb\u7597\u7684\u6a21\u5757\u5316\u5e73\u53f0<\/strong><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-128574\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2018\/03\/8-3.jpg\" alt=\"\" width=\"600\" height=\"561\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2018\/03\/8-3.jpg 600w, \/\/m.iemloyee.com\/wp-content\/uploads\/2018\/03\/8-3-300x281.jpg 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/p>\n<p>\u5229\u7528\u5355\u514b\u9686\u6297\u4f53\uff08mAbs\uff09\uff0c\u5728\u5f00\u53d1siRNA\u9776\u5411\u9012\u9001\u8f7d\u4f53\u65b9\u9762\u53d6\u5f97\u4e86\u91cd\u5927\u8fdb\u5c55\uff0c\u4f46\u5176\u4e34\u5e8a\u8f6c\u8bd1\u5c1a\u672a\u53d1\u751f\u3002\u90e8\u5206\u539f\u56e0\u662f\u5927\u91cf\u7684\u5f00\u53d1\u548c\u751f\u4ea7\u8981\u6c42\uff0c\u4ee5\u53ca\u4f9d\u8d56\u4e8e\u5316\u5b66\u5171\u8f6d\u6280\u672f\u7684\u6279\u6b21\u95f4\u53d8\u5316\u6027\u8f83\u9ad8\u3002\u8fd1\u65e5\uff0c<strong>\u4ee5\u8272\u5217\u7279\u62c9\u7ef4\u592b\u5927\u5b66Dan Peer\uff08\u901a\u8baf\u4f5c\u8005\uff09<\/strong>\u7b49\u4eba\u63d0\u51fa\u4e86\u4e00\u4e2a\u81ea\u7ec4\u88c5\u7684\u6a21\u5757\u5316\u5e73\u53f0\uff0c\u53ef\u4ee5\u6784\u5efa\u7406\u8bba\u4e0a\u65e0\u9650\u5236\u7684siRNA\u9776\u5411\u8f7d\u4f53\u3002\u8be5\u5e73\u53f0\u7684\u81ea\u7ec4\u88c5\u57fa\u4e8e\u819c\u951a\u5b9a\u86cb\u767d\uff0c\u8be5\u8102\u86cb\u767d\u7ed3\u5408\u5230\u8d1f\u8f7dsiRNA\u7684\u8102\u8d28\u7eb3\u7c73\u7c92\u5b50\u4e2d\u3002\u7814\u7a76\u8868\u660e\uff0c\u901a\u8fc7\u4f53\u5185\u4e0d\u540c\u767d\u7ec6\u80de\u4e9a\u7fa4\uff0c\u516b\u4e2a\u4e0d\u540c\u5355\u514b\u9686\u6297\u4f53\u7684\u7b80\u5355\u5f00\u5173\u53ef\u91cd\u5b9a\u5411siRNA\u7684\u7279\u5b9a\u6444\u53d6\u3002\u8fd9\u4e2a\u6a21\u5757\u5316\u7684\u4ea4\u4ed8\u5e73\u53f0\u4ee3\u8868\u4e86\u7cbe\u5bc6\u533b\u5b66\u53d1\u5c55\u7684\u4e00\u4e2a\u91cc\u7a0b\u7891\u3002<\/p>\n<p>\u6587\u732e\u94fe\u63a5\uff1a<a href=\"https:\/\/www.nature.com\/articles\/s41565-017-0043-5\" target=\"_blank\" rel=\"noopener\">A modular platform for targeted RNAi therapeutics<\/a>\uff08Nat. Nanotech.\uff0c2018\uff0cdoi:10.1038\/s41565-017-0043-5\uff09<\/p>\n<p><strong>9. Angew. Chem. Int. Ed.\uff1a\u9ad8\u80bf\u7624\u79ef\u7d2f\u548c\u523a\u6fc0\u54cd\u5e94\u5feb\u901f\u6d88\u9664\uff0c\u7eb3\u7c73\u80f6\u56ca\u7684\u8fd1\u7ea2\u5916\u89e6\u53d1\u5206\u89e3<\/strong><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-128575\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2018\/03\/9-1.jpg\" alt=\"\" width=\"600\" height=\"544\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2018\/03\/9-1.jpg 600w, \/\/m.iemloyee.com\/wp-content\/uploads\/2018\/03\/9-1-300x272.jpg 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/p>\n<p>2018\u5e742\u67086\u65e5\uff0c<strong>\u590d\u65e6\u5927\u5b66\u8d75\u4e1c\u5143\u9662\u58eb\u548c\u674e\u6653\u654f\u535a\u58eb\uff08\u5171\u540c\u901a\u8baf\u4f5c\u8005\uff09<\/strong>\u5c55\u793a\u4e86\u8fd1\u7ea2\u5916\uff08NIR\uff09\u8bf1\u5bfc\u7684\u53ef\u5206\u89e3\u805a\u5408\u7269\u7eb3\u7c73\u80f6\u56ca\u3002\u57fa\u4e8e\u5076\u6c2e\u82ef\u5b98\u80fd\u5316\u805a\u5408\u7269\u548c\u4e0a\/\u4e0b\u8f6c\u6362\u7eb3\u7c73\u9897\u7c92\uff08U \/ DCNPs\uff09\u7684\u9010\u5c42\u5171\u7ec4\u88c5\uff0c\u5236\u9020\u4e86\u7eb3\u7c73\u80f6\u56ca\u3002\u5f53\u7eb3\u7c73\u80f6\u56ca\u66b4\u9732\u4e8e980nm\u5149\u65f6\uff0c\u7531U \/ DCNP\u53d1\u5c04\u7684\u7d2b\u5916\/\u53ef\u89c1\u5149\u5b50\u53ef\u89e6\u53d1\u6846\u67b6\u4e2d\u5076\u6c2e\u82ef\u57fa\u56e2\u7684\u5149\u5f02\u6784\u5316\u3002\u7eb3\u7c73\u80f6\u56ca\u53ef\u4ee5\u4ece\u5927\u5c3a\u5bf8\u5206\u89e3\u6210\u5c0f\u7684U \/ DCNP\u3002\u7531\u4e8e\u5176\u4f18\u5316\u7684\u539f\u59cb\u5c3a\u5bf8\uff08\u7ea6180nm\uff09\uff0c\u7eb3\u7c73\u80f6\u56ca\u53ef\u6709\u6548\u907f\u514d\u751f\u7269\u5c4f\u969c\uff0c\u63d0\u4f9b\u957f\u65f6\u95f4\u7684\u8840\u6db2\u5faa\u73af\uff08\u534a\u8870\u671f\u7ea65\u5c0f\u65f6\uff09\uff0c\u5e76\u5b9e\u73b04\u500d\u7684\u80bf\u7624\u79ef\u7d2f\u3002\u5b83\u53ef\u4ee5\u57281\u5c0f\u65f6\u5185\u5feb\u901f\u4ece\u80bf\u7624\u4e2d\u6d88\u9664\uff0c\u5e76\u4e14\u5728\u8fd1\u7ea2\u5916\u89e6\u53d1\u4e0b\u91ca\u653e\u88c5\u8f7d\u836f\u7269\u7528\u4e8e\u5316\u5b66\u7597\u6cd5\u3002<\/p>\n<p>\u6587\u732e\u94fe\u63a5\uff1a<a href=\"http:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/anie.201711354\/full\" target=\"_blank\" rel=\"noopener\">Near-Infrared Triggered Decomposition of Nanocapsules with High Tumor Accumulation and Stimuli Responsive Fast Elimination<\/a>\uff08Angew. Chem. Int. Ed.\uff0c2018\uff0cDOI: 10.1002\/anie.201711354\uff09<\/p>\n<p>\u672c\u6587\u7531\u6750\u6599\u4eba\u7f16\u8f91\u90e8\u751f\u7269\u6750\u6599\u7ec4Meadow\u4f9b\u7a3f\uff0c\u6750\u6599\u725b\u6574\u7406\u7f16\u8f91\u3002<\/p>\n<p>\u6750\u6599\u725b\u7f51\u4e13\u6ce8\u4e8e\u8ddf\u8e2a\u6750\u6599\u9886\u57df\u79d1\u6280\u53ca\u884c\u4e1a\u8fdb\u5c55\uff0c\u8fd9\u91cc\u6c47\u96c6\u4e86\u5404\u5927\u9ad8\u6821\u7855\u535a\u751f\u3001\u4e00\u7ebf\u79d1\u7814\u4eba\u5458\u4ee5\u53ca\u884c\u4e1a\u4ece\u4e1a\u8005\uff0c\u5982\u679c\u60a8\u5bf9\u4e8e\u8ddf\u8e2a\u6750\u6599\u9886\u57df\u79d1\u6280\u8fdb\u5c55\uff0c\u89e3\u8bfb\u9ad8\u6c34\u5e73\u6587\u7ae0\u6216\u662f\u8bc4\u8ff0\u884c\u4e1a\u6709\u5174\u8da3\uff0c<a href=\"\/\/m.iemloyee.com\/25127.html\" target=\"_blank\" rel=\"noopener\">\u70b9\u6211\u52a0\u5165\u6750\u6599\u4eba\u7f16\u8f91\u90e8<\/a>\u3002\u53c2\u4e0e\u751f\u7269\u6750\u6599\u8bdd\u9898\u8ba8\u8bba\u6216\u4e86\u89e3\u751f\u7269\u6750\u6599\u5c0f\u7ec4\u62db\u52df\u8be6\u60c5\uff0c\u8bf7\u52a0\u5165\u6750\u6599\u4eba\u751f\u7269\u6750\u6599\u4ea4\u6d41\u7fa4\uff08124806506\uff09\u3002<\/p>\n<p>\u6b22\u8fce\u5927\u5bb6\u5230\u6750\u6599\u4eba\u5ba3\u4f20\u79d1\u6280\u6210\u679c\u5e76\u5bf9\u6587\u732e\u8fdb\u884c\u6df1\u5165\u89e3\u8bfb\uff0c\u6295\u7a3f\u90ae\u7bb1tougao@cailiaoren.com\u3002<\/p>\n<p>\u6295\u7a3f\u4ee5\u53ca\u5185\u5bb9\u5408\u4f5c\u53ef\u52a0\u7f16\u8f91\u5fae\u4fe1\uff1aRDD-2011-CHERISH , \u4efb\u4e39\u4e39\uff0c\u6211\u4eec\u4f1a\u9080\u8bf7\u5404\u4f4d\u8001\u5e08\u52a0\u5165\u4e13\u5bb6\u7fa4\u3002<\/p>\n<p><strong>\u6750\u6599\u6d4b\u8bd5\uff0c\u6570\u636e\u5206\u6790\uff0c\u4e0a<a href=\"http:\/\/www.ceshigu.com\/\" target=\"_blank\" rel=\"noopener\">\u6d4b\u8bd5\u8c37<\/a>\uff01<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u6750\u6599\u4eba\u63a8\u51fa\u751f\u7269\u6750\u6599\u6210\u679c\u6c47\u7f16\uff08\u6708\u520a\uff09\uff0c\u62a5\u9053\u8fd1\u671f\u751f\u7269\u6750\u6599\u76f8\u5173\u91cd\u5927\u6210\u679c\u3002 1. Adv. Mater.:\u7f13\u89e3\u8c37\u6c28\u9178\u8bf1\u5bfc\u7684\u5174\u594b\u6027\u6bd2\u6027\uff0c\u751f\u7269\u53ef\u964d\u89e3\u7403\u4f53\u4fdd\u62a4\u521b\u4f24\u6027\u810a\u9ad3\u635f\u4f24 &#8230;<\/p>\n","protected":false},"author":721,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2],"tags":[2548,75],"class_list":["post-128565","post","type-post","status-publish","format-standard","hentry","category-keji","tag-2548","tag-biomaterial"],"_links":{"self":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts\/128565"}],"collection":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/users\/721"}],"replies":[{"embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=128565"}],"version-history":[{"count":4,"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts\/128565\/revisions"}],"predecessor-version":[{"id":128915,"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts\/128565\/revisions\/128915"}],"wp:attachment":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=128565"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=128565"},{"taxonomy":"post_tag","embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=128565"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}