{"id":123993,"date":"2018-02-03T06:30:09","date_gmt":"2018-02-02T22:30:09","guid":{"rendered":"\/\/m.iemloyee.com\/?p=123993"},"modified":"2018-02-01T23:07:18","modified_gmt":"2018-02-01T15:07:18","slug":"nat-chem-%ef%bc%9a%e5%b7%a5%e7%a8%8b%e6%a8%a1%e5%9d%97%e5%8c%96%e7%94%9f%e7%89%a9%e6%9d%90%e6%96%99%e9%80%bb%e8%be%91%e9%97%a8%e7%94%a8%e4%ba%8e%e8%8d%af%e7%89%a9%e9%80%92%e9%80%81","status":"publish","type":"post","link":"\/\/m.iemloyee.com\/?p=123993","title":{"rendered":"Nat. Chem. \uff1a\u5de5\u7a0b\u6a21\u5757\u5316\u751f\u7269\u6750\u6599\u903b\u8f91\u95e8\u7528\u4e8e\u836f\u7269\u9012\u9001"},"content":{"rendered":"
\u3010\u5f15\u8a00\u3011<\/strong><\/p>\n \u8fd1\u5e74\u6765\u5728\u6cbb\u7597\u53d1\u5c55\u548c\u7ec6\u80de\u5de5\u7a0b\u65b9\u9762\u7684\u521b\u65b0\u5df2\u7ecf\u4ea7\u751f\u4e86\u6709\u529b\u7684\u624b\u6bb5\uff0c\u6765\u5bf9\u6297\u8d8a\u6765\u8d8a\u591a\u7684\u8870\u5f31\u548c\u5a01\u80c1\u751f\u547d\u7684\u75be\u75c5\u3002\u5c3d\u7ba1\u53d6\u5f97\u4e86\u4e0d\u9519\u7684\u8fdb\u5c55\uff0c\u4f46\u4e34\u5e8a\u5e94\u7528\u4ecd\u7136\u5b58\u5728\u4e00\u4e9b\u969c\u788d\uff0c\u7279\u522b\u662f\u5bf9\u4e8e\u672a\u77e5\u75be\u75c5\u90e8\u4f4d\u7684\u6cbb\u7597\u66f4\u662f\u4e00\u5927\u6311\u6218\u3002\u5229\u7528\u75be\u75c5\u76f8\u5173\u751f\u7269\u6807\u5fd7\u7269\u7684\u9776\u5411\u9012\u9001\u7b56\u7565\uff0c\u901a\u8fc7\u51cf\u5c11\u5242\u91cf\u9700\u6c42\u548c\u4e0d\u5229\u7684\u8131\u9776\u6548\u5e94\u53ef\u4ee5\u7528\u6765\u63d0\u9ad8\u6cbb\u7597\u6548\u7387\u548c\u529f\u6548\u3002\u6700\u5178\u578b\u7684\u662f\uff0c\u8fd9\u4e9b\u65b9\u6cd5\u4f7f\u7528\u57fa\u4e8e\u805a\u5408\u7269\u7684\u8f7d\u4f53\u6765\u4fc3\u8fdb\u9012\u9001\uff0c\u5e76\u4fdd\u62a4\u8f7d\u4f53\u514d\u53d7\u514d\u75ab\u8bc6\u522b\uff0c\u6e05\u9664\u548c\u975e\u7279\u5f02\u6027\u7ec6\u80de\u6444\u53d6\u3002<\/p>\n \u3010\u6210\u679c\u7b80\u4ecb\u3011<\/strong><\/p>\n \u8fd1\u65e5\uff0c\u534e\u76db\u987f\u5927\u5b66Cole A. DeForest\uff08\u901a\u8baf\u4f5c\u8005\uff09<\/strong>\u56e2\u961f\u7814\u53d1\u4e86\u4e00\u4e2a\u6a21\u5757\u5316\u7684\u5316\u5b66\u6846\u67b6\uff0c\u901a\u8fc7\u4f7f\u7528\u591a\u4e2a\u73af\u5883\u7ebf\u7d22\u6765\u89e6\u53d1\u64cd\u4f5c\u53ef\u7f16\u7a0b\u5e03\u5c14\u903b\u8f91\u7684\u53cd\u5e94\uff0c\u4e3a\u6c34\u51dd\u80f6\u63d0\u4f9b\u7cbe\u786e\u7684\u964d\u89e3\u54cd\u5e94\u3002\u901a\u8fc7\u5728\u7269\u8d28\u4ea4\u8054\u5242\u4e2d\u6307\u5b9a\u6b63\u4ea4\u523a\u6fc0-\u4e0d\u7a33\u5b9a\u90e8\u5206\u7684\u5206\u5b50\u7ed3\u6784\u548c\u8fde\u63a5\u6027\uff0c\u663e\u793a\u4e86\u5bf9\u51dd\u80f6\u6eb6\u89e3\u548c\u6cbb\u7597\u9012\u9001\u7684\u9009\u62e9\u6027\u63a7\u5236\u3002\u4e3a\u4e86\u8bf4\u660e\u8fd9\u79cd\u65b9\u6cd5\u7684\u591a\u529f\u80fd\u6027\uff0c\u5408\u6210\u4e8617\u79cd\u4e0d\u540c\u7684\u523a\u6fc0\u54cd\u5e94\u6750\u6599\uff0c\u8fd9\u4e9b\u6750\u6599\u5171\u540c\u4ece\u6d89\u53ca\u9176\uff0c\u8fd8\u539f\u5242\u548c\u5149\u7684\u8f93\u5165\u7ec4\u5408\u4e2d\u4ea7\u751f\u6240\u6709\u53ef\u80fd\u7684YES\/OR\/AND\u903b\u8f91\u8f93\u51fa\u3002\u4f7f\u7528\u8fd9\u4e9b\u6c34\u51dd\u80f6\uff0c\u56e2\u961f\u5c55\u793a\u4e86\u7b2c\u4e00\u987a\u5e8f\u548c\u73af\u5883\u523a\u6fc0\u91ca\u653e\u7684\u591a\u4e2a\u7ec6\u80de\u7cfb\u4ee5\u660e\u786e\u6750\u6599\u7684\u7ec4\u5408\u3002\u76f8\u5173\u6210\u679c\u4ee5\u9898\u4e3a\u201cEngineered modular biomaterial logic gates for environmentally triggered therapeutic delivery<\/strong>\u201d\u53d1\u8868\u5728\u4e86Nature Chemistry<\/strong>\u4e0a\u3002<\/p>\n \u3010\u56fe\u6587\u5bfc\u8bfb\u3011<\/strong><\/p>\n \u56fe1 \u5408\u7406\u8bbe\u8ba1\u7684\u4ea4\u8054\u4f53\u7cfb\u7ed3\u6784<\/strong><\/p>\n a\uff09YES\u95e8\u6750\u6599\u4ea4\u8054\u5242\u542b\u6709\u5355\u4e2a\u523a\u6fc0\u4e0d\u7a33\u5b9a\u90e8\u5206\uff08\u7ea2\u8272\uff09<\/p>\n b\uff09\u6216\u95e8\u4ea4\u8054\u5242\u542b\u6709\u4e24\u4e2a\u4e0d\u540c\u7684\u523a\u6fc0\u4e0d\u7a33\u5b9a\u90e8\u5206\uff08\u7ea2\u8272\u548c\u84dd\u8272\uff09<\/p>\n c\uff09\u4e0e\u95e8\u4ea4\u8054\u5242\u542b\u6709\u4e24\u4e2a\u4e0d\u540c\u7684\u523a\u6fc0\u4e0d\u7a33\u5b9a\u90e8\u5206\uff08\u7ea2\u8272\u548c\u84dd\u8272\uff09<\/p>\n d\uff09\u903b\u8f91\u95e8\u53ef\u4ee5\u5206\u5c42\u7ec4\u5408\u4ee5\u4ea7\u751f\u66f4\u9ad8\u9636\u7684\u903b\u8f91\u54cd\u5e94<\/p>\n 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\u8be5\u7814\u7a76\u9996\u6b21\u5f15\u5165\u4e86\u6a21\u5757\u5316\u65b9\u6cd5\u6765\u8bbe\u8ba1\u5177\u6709\u5b9a\u5236\u7684\uff0c\u7528\u6237\u6307\u5b9a\u7684\uff0c\u57fa\u4e8e\u903b\u8f91\u7684\u5bf9\u73af\u5883\u54cd\u5e94\u7684\u6750\u6599\u3002\u901a\u8fc7\u63a7\u5236\u79bb\u6563\u7684\u57fa\u4e8e\u80bd\u7684\u4ea4\u8054\u5242\u4e2d\u7684\u591a\u4e2a\u523a\u6fc0-\u4e0d\u7a33\u5b9a\u90e8\u5206\u7684\u5206\u5b50\u7ed3\u6784\u548c\u8fde\u63a5\u6027\uff0c\u901a\u8fc7\u5e03\u5c14YES\/OR\/AND\u95e8\u7684\u5206\u7ea7\u7ec4\u5408\u8d4b\u4e88\u751f\u7269\u6750\u6599\u524d\u6240\u672a\u6709\u7684\u8ba1\u7b97\u80fd\u529b\u3002\u671f\u671b\u8fd9\u4e9b\u5e73\u53f0\u5c06\u5728\u9776\u5411\u836f\u7269\u9012\u9001\u4e2d\u5177\u6709\u5f88\u5927\u7684\u5b9e\u7528\u6027\uff0c\u5176\u4e2d\u6cbb\u7597\u5242\uff0c\u86cb\u767d\u8d28\u548c\u7ec6\u80de\u7684\u91ca\u653e\u53ef\u4ee5\u9ad8\u5ea6\u9009\u62e9\u6027\u5730\u5b9a\u4e3a\u4e8e\u75be\u75c5\u90e8\u4f4d\uff0c\u53d7\u5230\u8be5\u7814\u7a76\u7684\u542f\u53d1\u76f8\u4fe1\u80fd\u66f4\u597d\u7684\u5e94\u7528\u4e8e\u8bca\u65ad\uff0c\u7ec4\u7ec7\u5de5\u7a0b\u548c\u518d\u751f\u533b\u5b66\u9886\u57df\u3002<\/p>\n \u6587\u732e\u94fe\u63a5\uff1a<\/strong>Engineered modular biomaterial logic gates for environmentally triggered therapeutic delivery<\/a>\uff08Nat. Chem.,2018,DOI:10.1038\/nchem.2917\uff09<\/p>\n \u672c\u6587\u7531\u6750\u6599\u4eba\u751f\u7269\u6750\u6599\u7ec4Allen\u4f9b\u7a3f\uff0c\u6750\u6599\u725b\u6574\u7406\u7f16\u8f91\u3002<\/p>\n \u6750\u6599\u725b\u7f51\u4e13\u6ce8\u4e8e\u8ddf\u8e2a\u6750\u6599\u9886\u57df\u79d1\u6280\u53ca\u884c\u4e1a\u8fdb\u5c55\uff0c\u8fd9\u91cc\u6c47\u96c6\u4e86\u5404\u5927\u9ad8\u6821\u7855\u535a\u751f\u3001\u4e00\u7ebf\u79d1\u7814\u4eba\u5458\u4ee5\u53ca\u884c\u4e1a\u4ece\u4e1a\u8005\uff0c\u5982\u679c\u60a8\u5bf9\u4e8e\u8ddf\u8e2a\u6750\u6599\u9886\u57df\u79d1\u6280\u8fdb\u5c55\uff0c\u89e3\u8bfb\u9ad8\u6c34\u5e73\u6587\u7ae0\u6216\u662f\u8bc4\u8ff0\u884c\u4e1a\u6709\u5174\u8da3\uff0c\u70b9\u6211\u52a0\u5165\u7f16\u8f91\u90e8\u5927\u5bb6\u5ead<\/a>\u3002<\/p>\n \u6b22\u8fce\u5927\u5bb6\u5230\u6750\u6599\u4eba\u5ba3\u4f20\u79d1\u6280\u6210\u679c\u5e76\u5bf9\u6587\u732e\u8fdb\u884c\u6df1\u5165\u89e3\u8bfb\uff0c\u6295\u7a3f\u90ae\u7bb1tougao@cailiaoren.com\u3002<\/p>\n \u6295\u7a3f\u4ee5\u53ca\u5185\u5bb9\u5408\u4f5c\u53ef\u52a0\u7f16\u8f91\u5fae\u4fe1\uff1aRDD-2011-CHERISH\uff0c\u4efb\u4e39\u4e39\uff0c\u6211\u4eec\u4f1a\u9080\u8bf7\u5404\u4f4d\u8001\u5e08\u52a0\u5165\u4e13\u5bb6\u7fa4\u3002
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