{"id":123979,"date":"2018-02-03T06:30:29","date_gmt":"2018-02-02T22:30:29","guid":{"rendered":"\/\/m.iemloyee.com\/?p=123979"},"modified":"2018-02-01T21:33:24","modified_gmt":"2018-02-01T13:33:24","slug":"%e8%a7%82%e7%82%b9%e4%b8%a8%e5%8c%96%e5%ad%a6%e5%8f%8d%e5%ba%94%e6%9c%89%e5%93%aa%e4%ba%9b%e5%a5%87%e8%91%a9%e7%9a%84%e5%8f%8d%e5%ba%94%e6%9d%a1%e4%bb%b6","status":"publish","type":"post","link":"\/\/m.iemloyee.com\/?p=123979","title":{"rendered":"\u89c2\u70b9\u4e28\u5316\u5b66\u53cd\u5e94\u6709\u54ea\u4e9b\u5947\u8469\u7684\u53cd\u5e94\u6761\u4ef6?"},"content":{"rendered":"<p>\u5929\u6c14\u8fd9\u4e48\u51b7\uff0c\u5148\u6765\u4e2a\u8001\u6897\u6696\u573a\u5427\uff0c\u5947\u8469\u7684\u53cd\u5e94\u6761\u4ef6\u5982\u4e0b\uff1a1\u3001\u610f\u5927\u5229\u9633\u5149\u7167\u4e00\u5e74\u4ea7\u7269\u5173\u73af\u4e86\uff0c\u66f4\u6709\u751a\u8005\u4e00\u4e2amodified\u7248\u672c\uff0c\u65f6\u95f4\u7f29\u77ed\u8fd1\u4e00\u534a\uff081\u5e74\u21926.5\u4e2a\u6708\uff09\uff0c\u770b\u6765\u897f\u6d77\u5cb8\u7684\u9633\u5149\u5c31\u662f\u6bd4\u5730\u4e2d\u6d77\u7684\u5145\u8db3\u554a\uff0c\u90a3\u4e48\u662f\u4e0d\u662f\u8dd1\u5230\u8d64\u9053\u9644\u8fd1\u5c31\u80fd\u5927\u5e45\u7f29\u77ed\u53cd\u6620\u65f6\u95f4\u5462\uff1f\u54c8\u54c8<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-123982\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2018\/01\/2-72.jpg\" alt=\"\" width=\"600\" height=\"319\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2018\/01\/2-72.jpg 600w, \/\/m.iemloyee.com\/wp-content\/uploads\/2018\/01\/2-72-300x160.jpg 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/p>\n<p>2.\u6709\u7684\u65f6\u5019\uff0c\u53cd\u5e94\u88c5\u7f6e\u7684\u5dee\u5f02\u4e5f\u4f1a\u9020\u6210\u4ea7\u7269\u7684\u5dee\u5f02\uff0c\u4f60\u770b\u7528\u5706\u5e95\u70e7\u74f6\u6216\u87ba\u7eb9\u76d6\u73bb\u7483\u5c0f\u74f6\u53ef\u4ee5\u5bfc\u81f4\u5bf9\u4e0d\u540c\u4ea7\u7269\u7684\u9009\u62e9\u6027\u3002<\/p>\n<p>The selectivity between ring-opening N-arylation and C-arylation was controlled by the choice of reaction vessel. While the C-2 arylated product (4aa) was the major product using Miura\u2019s condition, changing the reaction vessel from a round-bottomed flask to a screw-capped reaction vial shifts the preference from an arylation of the C-2 position to a ring-opening N-arylation.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-123986\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2018\/01\/1-68.jpg\" alt=\"\" width=\"600\" height=\"119\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2018\/01\/1-68.jpg 600w, \/\/m.iemloyee.com\/wp-content\/uploads\/2018\/01\/1-68-300x60.jpg 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/p>\n<p>3.\u5373\u4f7f\u6240\u7528\u5b9e\u9a8c\u88c5\u7f6e\u4e00\u6a21\u4e00\u6837\uff0c\u5728\u5c0f\u9f20\u8eab\u4e0a\u8fdb\u884c\u7684\u540c\u4e00\u4e2a\u5b9e\u9a8c\uff0c\u7537\u6027\u5b9e\u9a8c\u5458\u53ef\u80fd\u548c\u5973\u6027\u5b9e\u9a8c\u5458\u505a\u51fa\u7684\u7ed3\u679c\u4e0d\u540c\u5462\uff0c\u8be6\u89c1\uff1aSorge R E, Martin L J, Isbester K A, et al. Olfactory exposure to males, including men, causes stress and related analgesia in rodents[J]. Nature methods, 2014, 11(6): 629-632.<\/p>\n<p>4.\u50cf\u9f99\u867e\u58f3\u9ad8\u6e29\u78b3\u5316\u5236\u5907\u6c2e\u63ba\u6742\u6d3b\u6027\u70ad\uff0c\u62ff\u6765\u505a\u9ad8\u6027\u80fd\u7535\u50ac\u5316\u5242\uff1b\u6930\u5b50\u58f3\u70e7\u7684\u78b3\u5206\u5b50\u7b5b\u662f\u6700\u597d\u7684\u78b3\u5206\u5b50\u7b5b\uff1b\u7814\u7a76\u4eba\u5458\u80fd\u60f3\u5230\u7684\u78b3\u6e90\u6765\u505a\u8367\u5149\u78b3\u70b9\u7684\u57fa\u672c\u90fd\u6709\u7528\u8fc7\u00b7\u00b7\u00b7\u8fd9\u4e9b\u90fd\u5df2\u7ecf\u53f8\u7a7a\u89c1\u60ef\u4e86\uff0c\u53ef\u662f\u62ff\u86af\u8693\u6765\u505a\u53cd\u5e94\u50ac\u5316\u5242\u4e5f\u771f\u662f\u591f\u91cd\u53e3\u7684\u4e86\u3002\u4f60\u8fd8\u522b\u8bf4\uff0c\u4ea7\u7387\u8fd8\u633a\u9ad8\u3002Catalytic earthworms: in three-component cascade Mannich-Michael reactions<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-123994\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2018\/01\/1-69.jpg\" alt=\"\" width=\"600\" height=\"348\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2018\/01\/1-69.jpg 600w, \/\/m.iemloyee.com\/wp-content\/uploads\/2018\/01\/1-69-300x174.jpg 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/p>\n<p>5.\u770b\u5b8c\u86af\u8693\u5148\u8ba9\u770b\u5b98\u4eec\u7f13\u4e00\u7f13\uff0c\u6765\u4e2a\u5c0f\u6e05\u65b0\u7684\u5427\u3002\u67d0\u5b9e\u9a8c\u5ba4\u914d\u57f9\u517b\u57fa\u57f9\u517b\u83cc\u7684\u65f6\u5019\u9700\u8981\u6dfb\u52a0\u67d0\u79cd\u7279\u6b8a\u7684\u836f\u54c1\uff0c \u914d\u57f9\u517b\u57fa\u8981\u7528\u4e00\u79cd\u98df\u54c1\u7528\u7684\u516b\u79cd\u852c\u83dc\u6c41\u7684\u6613\u62c9\u7f50\u996e\u6599\uff0c\u6ca1\u9519\uff0c\u53ea\u8981\u96c6\u9f50\u516b\u79cd\u852c\u83dc\u7684\u6c41\u4f60\u5c31\u53ef\u4ee5\u53ec\u5524\u4f60\u8981\u57f9\u517b\u7684\u83cc\u4e86\uff0c\u91cc\u9762\u6709\u4ec0\u4e48\u82b9\u83dc\uff0c\u897f\u7ea2\u67ff\uff0c\u80e1\u841d\u535c\u4e4b\u7c7b\u7684\u516b\u79cd\u852c\u83dc\u6c41\uff0c\u57f9\u517b\u7684\u83cc\u53ea\u5728\u8fd8\u6709\u8fd9\u4e9b\u8425\u517b\u6210\u5206\u7684\u57f9\u517b\u57fa\u4e0a\u624d\u80fd\u957f\uff0c\u6709\u7684\u65f6\u5019\u505a\u5b9e\u9a8c\u8981\u8865\u5145\u4e00\u4e0b\u7ef4\u751f\u7d20\u5c31\u76f4\u63a5\u6765\u4e00\u7f50\uff0c\u542c\u8bf4\u4e00\u7f50\u8fd8\u4e0d\u4fbf\u5b9c\uff0c\u9999\u6e2f\u6765\u7684~ \u5c31\u662f\u8fd9\u4e2a\u4e1c\u897f~<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-124004\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2018\/01\/1-70.jpg\" alt=\"\" width=\"403\" height=\"594\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2018\/01\/1-70.jpg 403w, \/\/m.iemloyee.com\/wp-content\/uploads\/2018\/01\/1-70-204x300.jpg 204w\" sizes=\"(max-width: 403px) 100vw, 403px\" \/><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-124006\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2018\/01\/2-73.jpg\" alt=\"\" width=\"600\" height=\"600\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2018\/01\/2-73.jpg 600w, \/\/m.iemloyee.com\/wp-content\/uploads\/2018\/01\/2-73-150x150.jpg 150w, \/\/m.iemloyee.com\/wp-content\/uploads\/2018\/01\/2-73-300x300.jpg 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/p>\n<p>6.\u7528\u996e\u6599\u7684\u8bdd\u600e\u4e48\u80fd\u5c11\u4e86\u9152\u5462\uff1f14\u5e74Baran\u7684\u4e00\u7bc7Nature\u5c31\u4ee5\u9152\u505a\u6eb6\u5242\u8fdb\u884c\u53cd\u5e94\uff0c\u8fd8\u987a\u4fbf\u591a\u7b5b\u4e86\u51e0\u79cd\u9152\u5462\u3002Functionalized olefin cross-coupling to construct carbon\u2013carbon bonds\uff1a<\/p>\n<p>&nbsp;<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-124108\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2018\/01\/1-73.jpg\" alt=\"\" width=\"519\" height=\"597\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2018\/01\/1-73.jpg 519w, \/\/m.iemloyee.com\/wp-content\/uploads\/2018\/01\/1-73-261x300.jpg 261w\" sizes=\"(max-width: 519px) 100vw, 519px\" \/><\/p>\n<p>\u600e\u4e48\u6837\uff0c\u5927\u5e08\u559d\u70b9\u5c0f\u9152\u5c31\u80fd\u628a\u53cd\u5e94\u7ed9\u505a\u4e86\uff0c\u8f7b\u677e\u554a\uff01<\/p>\n<p>7.\u5f53\u7136\u6709\u4eba\u8f7b\u677e\u6709\u4eba\u60b2\u50ac\u4e86\uff0c\u6709\u7684\u5b9e\u9a8c\u6240\u9700\u8bd5\u5242\u6216\u4ea7\u7269\u7684\u6c14\u5473\u597d\u5c34\u5c2c\u7684\uff0c\u4f60\u770b\uff1a<\/p>\n<p>\u7eba\u7ec7\u5382\u6709\u4e00\u90e8\u5206\u7684\u7ea4\u7ef4\u9700\u8981\u5b9e\u9a8c\u5ba4\u8fdb\u884c\u5c0f\u91cf\u5408\u6210\u518d\u6269\u5927\uff0c\u5176\u4e2d\u4e00\u90e8\u5206\u9700\u8981\u7528\u5230\u4e59\u786b\u9187\uff0c\u8fd9\u662f\u4e00\u79cd\u5473\u9053\u5341\u5206\u7cdf\u7cd5\u7684\u7269\u8d28\uff0c\u4e0d\u80fd\u7528\u8bed\u8a00\u6765\u5f62\u5bb9\uff0c\u8981\u771f\u7684\u5f62\u5bb9\u7684\u8bdd\uff0c\u5927\u6982\u662f\u8fd9\u6837\u7684\uff1a\u6253\u5f00\u76d6\u5b50\uff0c\u5de8\u81ed\u4ece\u74f6\u76d6\u98d8\u51fa\u6765\uff0c\u7528\u9488\u7b52\u5c0f\u5fc3\u7ffc\u7ffc\u7684\u624e\u7834\u5185\u76d6\uff0c\u6b64\u65f6\u5473\u9053\u597d\u50cf\u4e00\u53ea\u6b7b\u4e86\u51e0\u5341\u5929\u7684\u8001\u9f20\uff0c\u53ea\u6709\u6076\u81ed\uff0c\u5e72\u51c0\u800c\u4e14\u4e0d\u505a\u4f5c\u3002<\/p>\n<p>\u771f\u5b9e\u6548\u679c\u662f\uff1a\u6ca1\u5e26\u9762\u7f69\u4f60\u4f1a\u88ab\u81ed\u5230\u5455\u5410\uff0c\u660f\u53a5\uff0c\u4f60\u611f\u89c9\u751f\u65e0\u53ef\u604b\uff0c\u4f60\u5c31\u6ca1\u95fb\u8fc7\u8fd9\u4e48\u81ed\u7684\u5473\u9053\uff0c\u597d\u50cf\u628a\u4e00\u53ea\u81ed\u4e86\u5f88\u591a\u5929\u7684\u8001\u9f20\u6d53\u7f29\u4e86\u4e00\u4e0b\uff0c\u7136\u540e\u6dfb\u4e00\u4e9b\u5927\u7caa\uff0c\u518d\u6d53\u7f29\u4e0b\uff0c\u7136\u540e\u52a0\u70b9\u786b\u5316\u6c22\u518d\u6d53\u7f29\u4e00\u4e0b\u3002\u4f60\u4f1a\u88ab\u718f\u5230\u6d41\u6cea\uff0c\u718f\u5012\u5728\u5730\u4e0a\u62bd\u6410\uff0c\u52a8\u4f5c\u7c7b\u4f3c\u4e8e\u4e00\u6761\u86c7\uff0c\u873f\u8712\u7740\u60f3\u722c\u51fa\u5b9e\u9a8c\u5ba4\u3002\u8863\u670d\u4e0a\u5168\u662f\u871c\u6c41\u5473\u9053\uff0c\u4f60\u4e0d\u6562\u547c\u5438\uff0c\u6bcf\u4e00\u6b21\u547c\u5438\u90fd\u5728\u6467\u6bc1\u4f60\u7684\u55c5\u89c9\u7ec6\u80de\uff0c\u4f60\u5fcd\u4e0d\u4f4f\u54c8\u4e86\u53e3\u6c14\uff0c\u95fb\u4e86\u95fb\u624b\uff0c\u4f60\u611f\u89c9\u53ef\u80fd\u7528\u624b\u73a9\u4e86\u5c4e\uff0c\u6700\u540e\u4f60\u770b\u4e86\u770b\u5b9e\u9a8c\u5ba4\uff0c\u611f\u89c9\u4f60\u7684\u4eba\u751f\u90fd\u88ab\u8fd9\u5473\u9053\u6bc1\u6389\u4e86\u00b7\u00b7\u00b7<\/p>\n<p>8.\u8fd8\u6709\u8fd9\u4e2a\uff0c\u8fd9\u4e2a\u4e5f\u5f88\u641e\u7b11\uff1a<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-124110\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2018\/01\/2-75.jpg\" alt=\"\" width=\"600\" height=\"359\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2018\/01\/2-75.jpg 600w, \/\/m.iemloyee.com\/wp-content\/uploads\/2018\/01\/2-75-300x180.jpg 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/p>\n<p>9.\u6700\u540e\u6765\u4e2a\u8111\u6d1e\u5927\u5f00\u7684\uff0c\u5565\u4e5f\u4e0d\u8bf4\u4e86\uff0c\u4e2d\u534e\u6709\u795e\u529f\u554a\uff0c\u770b\u5b98\u81ea\u5df1\u4f53\u4f1a\u5427<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-124111\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2018\/01\/1-74.jpg\" alt=\"\" width=\"600\" height=\"1067\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2018\/01\/1-74.jpg 600w, \/\/m.iemloyee.com\/wp-content\/uploads\/2018\/01\/1-74-169x300.jpg 169w, \/\/m.iemloyee.com\/wp-content\/uploads\/2018\/01\/1-74-576x1024.jpg 576w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/p>\n<p>\u672c\u6587\u8f6c\u8f7d\u81ea\u77e5\u4e4e\uff1a<a href=\"https:\/\/www.zhihu.com\/question\/61754141\" target=\"_blank\" rel=\"noopener\">https:\/\/www.zhihu.com\/question\/61754141<\/a>\u3002<\/p>\n<p>\u6750\u6599\u725b\u77f3\u5c0f\u6885\u7f16\u8f91\u6574\u7406\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u5929\u6c14\u8fd9\u4e48\u51b7\uff0c\u5148\u6765\u4e2a\u8001\u6897\u6696\u573a\u5427\uff0c\u5947\u8469\u7684\u53cd\u5e94\u6761\u4ef6\u5982\u4e0b\uff1a1\u3001\u610f\u5927\u5229\u9633\u5149\u7167\u4e00\u5e74\u4ea7\u7269\u5173\u73af\u4e86\uff0c\u66f4\u6709\u751a\u8005\u4e00\u4e2amodified\u7248\u672c\uff0c\u65f6\u95f4\u7f29\u77ed\u8fd1\u4e00\u534a\uff081\u5e74\u21926.5\u4e2a\u6708\uff09\uff0c\u770b\u6765\u897f\u6d77&#8230;<\/p>\n","protected":false},"author":2832,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[234],"tags":[],"class_list":["post-123979","post","type-post","status-publish","format-standard","hentry","category-guandian"],"_links":{"self":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts\/123979"}],"collection":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/users\/2832"}],"replies":[{"embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=123979"}],"version-history":[{"count":1,"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts\/123979\/revisions"}],"predecessor-version":[{"id":124112,"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts\/123979\/revisions\/124112"}],"wp:attachment":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=123979"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=123979"},{"taxonomy":"post_tag","embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=123979"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}