{"id":121654,"date":"2018-01-17T14:00:38","date_gmt":"2018-01-17T06:00:38","guid":{"rendered":"\/\/m.iemloyee.com\/?p=121654"},"modified":"2018-01-15T22:23:31","modified_gmt":"2018-01-15T14:23:31","slug":"%e5%a4%a9%e5%a4%a7adv-funct-mater-%ef%bc%9a%e5%88%9a%e6%80%a7%e5%bd%a2%e7%8a%b6%e8%ae%b0%e5%bf%86%e6%b0%b4%e5%87%9d%e8%83%b6%e5%bc%b9%e7%b0%a7%e5%9c%88%e6%88%90%e5%8a%9f%e5%ae%9e%e7%8e%b0%e8%82%be","status":"publish","type":"post","link":"\/\/m.iemloyee.com\/?p=121654","title":{"rendered":"\u5929\u5927Adv. Funct. Mater.\uff1a\u521a\u6027\u5f62\u72b6\u8bb0\u5fc6\u6c34\u51dd\u80f6\u5f39\u7c27\u5708\u6210\u529f\u5b9e\u73b0\u80be\u52a8\u8109\u6813\u585e"},"content":{"rendered":"<p><strong>\u3010\u5f15\u8a00\u3011<\/strong><\/p>\n<p>\u52a8\u8109\u7624\u662f\u4e00\u79cd\u52a8\u8109\u58c1\u5185\u7684\u6c14\u7403\u72b6\u9686\u8d77\uff0c\u5176\u53d1\u75c5\u53ef\u5bfc\u81f4\u5371\u53ca\u751f\u547d\u7684\u51fa\u8840\u3002\u5728\u4e34\u5e8a\u75c5\u4f8b\u4e2d\u7ecf\u5bfc\u7ba1\u52a8\u8109\u6813\u585e\u672f\uff08TAE\uff09\u7531\u4e8e\u5176\u98ce\u9669\u4f4e\uff0c\u6210\u529f\u7387\u9ad8\u4ee5\u53ca\u5fae\u521b\u624b\u672f\u7b49\u4f18\u70b9\u88ab\u5e7f\u6cdb\u63a5\u53d7\u4e3a\u6cbb\u7597\u52a8\u8109\u7624\u7684\u6709\u6548\u65b9\u6cd5\u3002TAE\u6280\u672f\u901a\u5e38\u662f\u5229\u7528\u5bfc\u7ba1\u5c06\u91d1\u5c5e\u5fae\u7ebf\u5708\uff08\u4f8b\u5982\u94c2\u7ebf\u5708\uff09\u9012\u9001\u5230\u76ee\u6807\u8840\u7ba1\u4e2d\uff0c\u963b\u65ad\u8840\u6db2\u4f9b\u5e94\u5f15\u53d1\u7f3a\u8840\u6027\u574f\u6b7b\uff0c\u9632\u6b62\u52a8\u8109\u7624\u7834\u88c2\u3002<\/p>\n<p>\u4e34\u5e8a\u4e0a\u4f7f\u7528\u91d1\u5c5e\u5fae\u7ebf\u5708\u5b9e\u73b0\u7684\u6813\u585e\u6210\u529f\u7387\u901a\u5e38\u572815\uff05\u4ee5\u4e0b\uff0c\u5e76\u4e14\u9700\u8981\u91cd\u590d\u6cbb\u7597\uff0c\u8fd9\u5c31\u4e0d\u53ef\u907f\u514d\u5730\u5bfc\u81f4\u4e86\u52a8\u8109\u7624\u58c1\u7684\u518d\u6b21\u66b4\u9732\u548c\u6f5c\u5728\u7684\u7834\u88c2\u98ce\u9669\u3002\u968f\u7740\u7814\u7a76\u7684\u53d1\u5c55\uff0c\u76ee\u524d\u5e38\u7528\u7684\u91d1\u5c5e\u7ebf\u5708\u7684\u66ff\u4ee3\u7269\uff08\u5982\u53ef\u81a8\u80c0\u5f62\u72b6\u8bb0\u5fc6\u805a\u5408\u7269\u6d82\u5c42\u548c\u5fae\u7ebf\u5708\uff09\uff0c\u5728\u964d\u89e3\u671f\u95f4\u5176\u9010\u6e10\u81a8\u80c0\u53ef\u80fd\u5bfc\u81f4\u6cbb\u7597\u9885\u5185\u52a8\u8109\u7624\u8111\u79ef\u6c34\u53d1\u751f\u7387\u66f4\u9ad8\u3002\u8fd9\u4e9b\u65b0\u7814\u53d1\u7684\u751f\u7269\u53ef\u964d\u89e3\u805a\u5408\u7269\u6813\u585e\u6750\u6599\u7531\u4e8e\u968f\u65f6\u95f4\u63a8\u79fb\u4f1a\u53d1\u751f\u4f53\u5185\u8d28\u91cf\u635f\u5931\uff0c\u5e76\u4e0d\u9002\u5408\u4e8e\u6301\u4e45\u7684\u963b\u585e\uff0c\u56e0\u6b64\u7814\u53d1\u5b89\u5168\u548c\u6c38\u4e45\u7684\u52a8\u8109\u7624\u6813\u585e\u6750\u6599\u5bf9\u4e8e\u4e34\u5e8a\u5e94\u7528\u800c\u8a00\u662f\u4e2a\u6781\u5927\u7684\u6311\u6218\u3002<\/p>\n<p><strong>\u3010\u6210\u679c\u7b80\u4ecb\u3011<\/strong><\/p>\n<p>\u8fd1\u65e5\uff0c<strong>\u5929\u6d25\u5927\u5b66\u5218\u6587\u5e7f\u6559\u6388<\/strong>\u548c<strong>\u5929\u6d25\u5e02\u4e00\u4e2d\u5fc3\u533b\u9662\u7684\u51af\u5b66\u6cc9\u4e3b\u4efb\u533b\u5e08\uff08\u5171\u540c\u901a\u8baf\u4f5c\u8005\uff09<\/strong>\u56e2\u961f\u5728<strong>Adv. Funct. Mater.<\/strong>\u5728\u7ebf\u53d1\u8868\u4e86\u4e00\u7bc7\u9898\u4e3a\u201c<strong>Radiopaque Highly Stiff and Tough Shape Memory Hydrogel Microcoils for Permanent Embolization of Arteries<\/strong>\u201d\u7684\u6587\u7ae0\uff0c\u4ecb\u7ecd\u4e86\u4e00\u79cd\u5177\u6709X\u5149\u6210\u50cf\u529f\u80fd\u7684\u9ad8\u6a21\u91cf\u9ad8\u5f3a\u5ea6\u4f53\u6e29\u523a\u6fc0\u7684\u5f62\u72b6\u8bb0\u5fc6\u6c34\u51dd\u80f6\uff0c\u9996\u6b21\u5b9e\u73b0\u4e86\u9ad8\u5f3a\u5ea6\u6c34\u51dd\u80f6\u5bf9\u4e8e\u52a8\u8109\u8840\u7ba1\u7684\u6813\u585e\u3002\u4f5c\u8005\u6307\u51fa\uff0c\u8fd9\u79cd\u51dd\u80f6\u7f51\u7edc\u542b\u6709\u805a\u4e19\u70ef\u8148\u7684\u5076\u6781-\u5076\u6781\u76f8\u4e92\u4f5c\u7528\/\u805a\u4e19\u70ef\u9170\u80fa\u7684\u6c22\u952e\u7269\u7406\u4f5c\u7528\u53ca\u957f\u94fe\u805a\u4e59\u4e8c\u9187\u4e8c\u7532\u57fa\u4e19\u70ef\u9178\u916f\u7684\u5316\u5b66\u4ea4\u8054\uff0c\u5e76\u4e14\u5e7f\u89d2X\u5c04\u7ebf\u884d\u5c04\u3001\u5c0f\u89d2X\u5c04\u7ebf\u6563\u5c04\u7ed3\u679c\u8868\u660e\uff0c\u5076\u6781\u5bf9\u5f62\u6210\u7684\u7ed3\u6676\u758f\u6c34\u5fae\u533a\u5bf9\u4e8e\u63d0\u9ad8\u51dd\u80f6\u7684\u6c34\u73af\u5883\u7a33\u5b9a\u6027\u548c\u6a21\u91cf\u81f3\u5173\u91cd\u8981\u3002<\/p>\n<p><strong>\u3010\u56fe\u6587\u5bfc\u8bfb\u3011<\/strong><\/p>\n<p><strong>\u56fe1.\u00a0<\/strong><strong>\u6c34\u51dd\u80f6\u4e2d\u53cc\u91cd\u7269\u7406\u4ea4\u8054\u7ed3\u6784\u793a\u610f\u56fe<\/strong><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-121703\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2018\/01\/figures-1.jpg\" alt=\"\" width=\"600\" height=\"444\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2018\/01\/figures-1.jpg 600w, \/\/m.iemloyee.com\/wp-content\/uploads\/2018\/01\/figures-1-300x222.jpg 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/p>\n<p>\u6709\u673a\u51dd\u80f6\u7531\u6709\u673a\u76f8\u8f6c\u5316\u4e3a\u6c34\u76f8\u65f6\uff0c\u4f1a\u53d1\u751f\u53cc\u91cd\u7269\u7406\u4ea4\u8054\u800c\u5f62\u6210\u6c34\u51dd\u80f6\u3002<\/p>\n<p><strong>\u56fe2.<\/strong> <strong>PAN\u2013PAAm\u2013PEG3kDMA<\/strong><strong>\u6c34\u51dd\u80f6\u7269\u7406\u6027\u80fd\u8868\u5f81<\/strong><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-121705\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2018\/01\/figures-2.jpg\" alt=\"\" width=\"600\" height=\"691\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2018\/01\/figures-2.jpg 600w, \/\/m.iemloyee.com\/wp-content\/uploads\/2018\/01\/figures-2-260x300.jpg 260w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/p>\n<p>A\uff09 PAN\u2013PAAm\u2013PEG3kDMA\u6c34\u51dd\u80f6\u5206\u5b50\u7ed3\u6784\uff1b<\/p>\n<p>B\uff09 \u4e0d\u540cAN\uff08\u4e19\u70ef\u8148\uff09\u542b\u91cf\u7684PAN\u2013PAAm\u2013PEG3kDMA\u6c34\u51dd\u80f6\u7684\u5e7f\u89d2\u4e00\u7ef4\u884d\u5c04\u66f2\u7ebf\uff1b<\/p>\n<p>C\uff09\u6c34\u51dd\u80f6\u50a8\u80fd\u6a21\u91cf\uff08G&#8217;\uff09\uff0c\u635f\u8017\u6a21\u91cf\uff08G&#8221;\uff09\u548c\u635f\u8017\u56e0\u5b50\uff08tan\u03b4\uff09\u7684\u6e29\u5ea6\u4f9d\u8d56\u6027\u66f2\u7ebf\uff08R<sub>AN<\/sub> = 66 wt\uff05\uff0cC<sub>PLY<\/sub> = 25\uff05\uff0cR<sub>PEG<\/sub> = 12 wt\uff05\uff0c\u632f\u5e45\uff1a10 \u03bcm\uff0c\u9891\u7387\uff1a1Hz\uff09;<\/p>\n<p>D\uff09\u4e0d\u540c\u6e29\u5ea6\u4e0b\u7684\u6c34\u51dd\u80f6\u7684\u52a0\u8f7d\u5378\u8f7d\u5e94\u529b\u5e94\u53d8\u66f2\u7ebf\uff1b<\/p>\n<p>E\uff09\u54d1\u94c3\u5f62\u6c34\u51dd\u80f6\u6837\u54c1\u572825\u00b0C \uff08E1\uff09\u548c37\u00b0C\uff08E2\uff09\u6c34\u6d74\u4e2d\u7684\u62c9\u4f38\u8bd5\u9a8c\uff0c\u7ea2\u8272\u5706\u5708\uff1a\u6c34\u51dd\u80f6\u6837\u54c1\u7684\u9888\u7f29\u533a\u57df\uff0c\u800c\u572837\u2103\u65f6\u6ca1\u6709\u9888\u7f29\u73b0\u8c61\u3002<\/p>\n<p><strong>\u56fe3. \u6c34\u51dd\u80f6\u4f53\u5916\u5f62\u72b6\u8bb0\u5fc6\u5b9e\u9a8c<\/strong><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-121706 aligncenter\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2018\/01\/figures-3.jpg\" alt=\"\" width=\"600\" height=\"641\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2018\/01\/figures-3.jpg 600w, \/\/m.iemloyee.com\/wp-content\/uploads\/2018\/01\/figures-3-281x300.jpg 281w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/p>\n<p>B\uff09 \u663e\u5f71\u6c34\u51dd\u80f6\u7ebf\u5708\u7684\u5236\u5907\u793a\u610f\u56fe\uff1b<\/p>\n<p>C\uff09 \u65e0\u7ea6\u675f\u7684\u6c34\u51dd\u80f6\u5f39\u7c27\u5708\u7684\u5f62\u72b6\u8bb0\u5fc6\u8fc7\u7a0b\uff1b<\/p>\n<p>D\uff09 \u6c34\u51dd\u80f6\u5fae\u5f39\u7c27\u5708\u7ecf\u5bfc\u7ba1\u9012\u9001\u523037\u00a0\u2103\u6c34\u4e2d\u7684\u73bb\u7483\u7ba1\u5185\u7684\u5f62\u72b6\u8bb0\u5fc6\u8fc7\u7a0b\u3002<\/p>\n<p><strong>\u56fe<\/strong><strong>4. <\/strong><strong>\u6c34\u51dd\u80f6\u4f53\u5185\u6813\u585e\u8bc4\u4ef7<\/strong><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-121707\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2018\/01\/figures-4.jpg\" alt=\"\" width=\"600\" height=\"578\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2018\/01\/figures-4.jpg 600w, \/\/m.iemloyee.com\/wp-content\/uploads\/2018\/01\/figures-4-300x289.jpg 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/p>\n<p>A\uff09 TAE\u8fc7\u7a0b\u7684\u793a\u610f\u56fe\u3002\u521a\u6027\u7684\u6c34\u51dd\u80f6\u76f4\u6761\u5728\u51b7\u76d0\u6c34\u7684\u4fdd\u62a4\u4e0b\u7ecf\u5bfc\u7ba1\u88ab\u9012\u9001\u81f3\u76ee\u6807\u80be\u52a8\u8109\u4e2d\uff0c\u63a5\u89e6\u201c\u70ed\u8840\u201d\u540e\uff0c\u51dd\u80f6\u76f4\u6761\u8fc5\u901f\u8f6c\u53d8\u4e3a\u5f39\u7c27\u5f62\u72b6\u5e76\u7f20\u7ed3\u5728\u4e00\u8d77\uff0c\u963b\u65ad\u52a8\u8109\u8840\u6db2\u4f9b\u7ed9\uff1b<\/p>\n<p>B\uff09 \u53ef\u663e\u5f71\u6c34\u51dd\u80f6\u5f39\u7c27\u5708\u4f53\u5185\u5f62\u72b6\u8bb0\u5fc6\u8fc7\u7a0b\u7684X\u5c04\u7ebf\u5f71\u50cf\u56fe\uff08\u9ec4\u8272\u5706\u70b9\u4e3a\u5f39\u7c27\u5708\u8f6e\u5ed3\uff09\uff1b<\/p>\n<p>C\uff09 \u672f\u540e\u95f4\u9694\u4e0d\u540c\u65f6\u95f4\uff084\u5468\uff0c8\u5468\uff0c12\u5468\uff09\u7684\u590d\u67e5\u8840\u7ba1\u9020\u5f71\u56fe\u50cf\uff0c\u7ea2\u8272\u5706\u5708\u8868\u793a\u6c34\u51dd\u80f6\u5f39\u7c27\u5708\u7684\u4f4d\u7f6e\uff1b<\/p>\n<p>D\uff09 \u672f\u540e\u95f4\u9694\u4e0d\u540c\u65f6\u95f4\uff084\u5468\uff0c8\u5468\uff0c12\u5468\uff09\u5bf9\u732a\u8fdb\u884c\u89e3\u5256\u5f97\u5230\u7684\u80be\u810f\u56fe\u7247\uff08scale bar : 2cm\uff09\u3002<\/p>\n<p><strong>\u56fe<\/strong><strong>5. <\/strong><strong>\u4e0d\u540c\u5904\u7406\u7ec4\u80be\u810f\u75c5\u7406\u5206\u6790<\/strong><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-121708\" src=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2018\/01\/figures-5.jpg\" alt=\"\" width=\"600\" height=\"613\" srcset=\"\/\/m.iemloyee.com\/wp-content\/uploads\/2018\/01\/figures-5.jpg 600w, \/\/m.iemloyee.com\/wp-content\/uploads\/2018\/01\/figures-5-294x300.jpg 294w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/p>\n<p>A1-C1\uff09 \u6813\u585e\u672f\u540e4\uff0c8\uff0c12\u5468\u80be\u810f\u75c5\u7406\u5206\u6790\uff1b<\/p>\n<p>A2-C2\uff09\u6813\u585e\u5bf9\u4fa7\u80be\u810f\u7684\u75c5\u7406\u5206\u6790\u3002<\/p>\n<p><strong>\u3010\u5c0f\u7ed3\u3011<\/strong><\/p>\n<p>\u5229\u7528AN\uff08\u5076\u6781\u5355\u4f53\uff09\uff0cAAm\uff08\u6c22\u952e\u5355\u4f53\uff09\u548cPEG3kDMA\u7684\u7b80\u5355\u5171\u805a\u5408,\u7136\u540e\u76f4\u63a5BaSO<sub>4<\/sub>\u6c89\u6dc0\uff0c\u6210\u529f\u5236\u5907\u4e86\u4e00\u79cd\u4e0d\u900f\u5c04\u7ebf\u7684\u521a\u6027\u5f62\u72b6\u8bb0\u5fc6\u6c34\u51dd\u80f6\uff0c\u5e76\u5bf9\u6c34\u51dd\u80f6\u7684\u6e29\u5ea6\u54cd\u5e94\u884c\u4e3a\u8fdb\u884c\u4e86\u6df1\u5165\u7814\u7a76\u3002\u540c\u65f6\u5229\u7528\u732a\u80be\u810f\u6a21\u62df\u6813\u585e\u8fc7\u7a0b\uff0c\u5728\u4e09\u4e2a\u6708\u7684\u6813\u585e\u671f\u95f4\u6ca1\u6709\u89c2\u5bdf\u5230\u8840\u7ba1\u518d\u901a\uff0c\u6210\u529f\u5730\u5ef6\u957f\u4e86\u6813\u585e\u65f6\u95f4\u548c\u6813\u585e\u7684\u7a33\u5b9a\u6027\uff0c\u8fd9\u4e00\u7814\u7a76\u4e3a\u540e\u7eed\u4e34\u5e8a\u7528\u52a8\u8109\u7624\u6813\u585e\u6750\u6599\u7684\u76f8\u5173\u7814\u7a76\u63d0\u4f9b\u4e86\u65b0\u7684\u7814\u7a76\u601d\u8def\u548c\u65b9\u6cd5\u3002<\/p>\n<p><strong>\u6587\u732e\u94fe\u63a5\uff1a<\/strong><a href=\"http:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/adfm.201705962\/full\" target=\"_blank\" rel=\"noopener\">Radiopaque Highly Stiff and Tough Shape Memory Hydrogel Microcoils for Permanent Embolization of Arteries<\/a>\uff08Adv. Funct. 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