{"id":12102,"date":"2016-05-15T10:49:14","date_gmt":"2016-05-15T02:49:14","guid":{"rendered":"\/\/m.iemloyee.com\/?p=12102"},"modified":"2016-05-15T17:01:49","modified_gmt":"2016-05-15T09:01:49","slug":"nature-communications%e5%b7%a7%e5%a6%99%e5%88%a9%e7%94%a8%e8%9b%8b%e7%99%bd%e8%b4%a8%e7%b2%be%e7%a1%ae%e5%bc%95%e5%af%bc%e5%af%8c%e5%8b%92%e7%83%af%e6%99%b6%e4%bd%93%e8%87%aa%e7%bb%84%e8%a3%85","status":"publish","type":"post","link":"\/\/m.iemloyee.com\/?p=12102","title":{"rendered":"Nature Communications:\u5de7\u5999\u5229\u7528\u86cb\u767d\u8d28\u7cbe\u786e\u5f15\u5bfc\u5bcc\u52d2\u70ef\u6676\u4f53\u81ea\u7ec4\u88c5"},"content":{"rendered":"

\"22-researchersc\"<\/p>\n

\u7f8e\u56fd\u8fbe\u7279\u8305\u65af\u5b66\u9662Gevorg Grigoryan\u548c\u4ed6\u7684\u5408\u4f5c\u4f19\u4f34\u7814\u7a76\u51fa\u4e00\u79cd\u795e\u5947\u7684\u4eba\u9020\u86cb\u767d\u8d28\uff0c\u591f\u751f\u4ea7\u51fa\u7eb3\u7c73\u5c3a\u5ea6\u7684\u65b0\u6750\u6599\u3002<\/p>\n

\u5bcc\u52d2\u70ef\uff08\u5373C60\uff09\u5177\u6709\u826f\u597d\u7684\u8010\u9ad8\u6e29\u548c\u8d85\u5bfc\u6027\u800c\u5e38\u5e38\u5728\u7eb3\u7c73\u6280\u672f\u4e2d\u53d1\u6325\u4f5c\u7528\uff0c\u4f46\u662f\u8fd9\u79cd\u5206\u5b50\u5f88\u96be\u4ee5\u7406\u60f3\u7684\u65b9\u5f0f\u7ec4\u5408\u5728\u4e00\u8d77\uff0c\u8fd9\u5927\u5927\u963b\u788d\u4e86\u5b83\u5728\u65b0\u578b\u6750\u6599\u53d1\u5c55\u4e2d\u7684\u5e94\u7528\u3002\u7814\u7a76\u4eba\u5458\u8fd1\u65e5\u5229\u7528\u86cb\u767d\u8d28\u4e0eC60\u590d\u5408\uff0c\u5e76\u6210\u529f\u5229\u7528\u86cb\u767d\u8d28\u7684\u5f15\u5bfc\u4f5c\u7528\uff0c\u4f7f\u5f97C60\u7ec4\u88c5\u6210\u8bbe\u8ba1\u7684\u4e09\u7ef4\u6676\u4f53\u7ed3\u6784\uff0c\u6240\u5f97\u7684\u6676\u4f53\u5177\u6709\u826f\u597d\u7684\u5bfc\u7535\u6027\uff0c\u800c\u8fd9\u4e00\u65b0\u7684\u7279\u6027\u662f\u86cb\u767d\u8d28\u6676\u4f53\u548c\u65e0\u5b9a\u578bC60\u90fd\u4e0d\u5177\u5907\u7684\u3002<\/p>\n

\u8fd9\u79cd\u86cb\u767d\u8d28\u4e0e\u5bcc\u52d2\u70ef\u7684\u590d\u5408\u5c1a\u5c5e\u9996\u6b21\uff0c\u7814\u7a76\u4eba\u5458\u6210\u529f\u7684\u8868\u5f81\u4e86\u5176\u6676\u4f53\u7684\u4e09\u7ef4\u7ed3\u6784\u5e76\u53d1\u73b0\uff0c\u86cb\u767d\u8d28\u5728\u539f\u5b50\u5206\u5b50\u6c34\u5e73\u5bf9\u5206\u5b50\u7ec4\u88c5\u7684\u826f\u597d\u7684\u5f15\u5bfc\u4f5c\u7528\uff0c\u662f\u4e00\u79cd\u80fd\u591f\u5b9e\u73b0\u5206\u5b50\u7ec4\u88c5\u5f97\u5230\u6240\u9700\u7684\u6750\u6599\u6027\u8d28\u7684\u65b0\u65b9\u6cd5\u3002<\/p>\n

\u3010\u6587\u732e\u5bfc\u8bfb\u3011<\/strong><\/p>\n

\u6458\u8981<\/strong>\uff1a\u7814\u7a76\u8bbe\u8ba1\u81ea\u7ec4\u88c5\u80fd\u591f\u901a\u8fc7\u8bbe\u8ba1\u4f7f\u5f97\u5206\u5b50\u7684\u7cbe\u786e\u88c5\u914d\uff0c\u4ee5\u83b7\u5f97\u5177\u6709\u5b9a\u5236\u7279\u6027\u7684\u6750\u6599\u3002\u6211\u4eec\u7684\u7814\u7a76\u8bc1\u5b9e\uff0c\u86cb\u767d\u8d28\u80fd\u591f\u5f15\u5bfc\u5bcc\u52d2\u70ef\uff08\u5373C60\uff09\u5f62\u6210\u6709\u5e8f\u7684\u8d85\u6676\u683c\u7ed3\u6784\u3002\u5148\u524d\u6240\u8bbe\u8ba1\u7684\u56db\u805a\u4f53\u87ba\u65cb\u675f\u4e0eC60\u5728\u6eb6\u6db2\u4e2d\u7ed3\u5408\uff0c\u4f7f\u5176\u5177\u6709\u6c34\u6eb6\u6027\u3002\u4e24\u4e2a\u56db\u805a\u4f53\u4e0e\u4e00\u4e2aC60\u8fde\u63a5\uff0c\u4fc3\u4f7f\u5176\u8fdb\u4e00\u6b65\u7684\u7ec4\u88c5\uff0c\u53cd\u6620\u5728\u4e00\u4e2a1.67\u00c5\u7684\u6676\u4f53\u7ed3\u6784\u4e2d\u3002\u5bcc\u52d2\u70ef\u57fa\u56e2\u5360\u636e\u4e86\u5468\u671f\u6027\u7684\u6676\u683c\u4f4d\u70b9\uff0c\u5939\u5728\u76f8\u90bb\u56db\u805a\u4f53\u7684\u916a\u6c28\u9178\u6b8b\u57fa\u4e4b\u95f4\u3002\u503c\u5f97\u6ce8\u610f\u7684\u662f\uff0c\u8fd9\u6837\u7684\u7ec4\u88c5\u8868\u73b0\u51fa\u9ad8\u7535\u8377\u5bfc\u901a\u6027\uff08\u5373\u5bfc\u7535\u6027\uff09\uff0c\u800c\u7eaf\u86cb\u767d\u8d28\u6676\u4f53\u548c\u65e0\u5b9a\u578b\u7684C60\u90fd\u662f\u7535\u7edd\u7f18\u7684\u3002\u7531\u4e8eC60\u6676\u4f53\u7ed3\u5408\u4f4d\u70b9\u800c\u4ea7\u751f\u7684\u4eb2\u548c\u6027\u636e\u4f30\u7b97\u5728\u7eb3\u6469\u5c14\u91cf\u7ea7\u8303\u56f4\uff0c\u5305\u542b\u4e0e\u5df2\u77e5\u86cb\u767d\u8d28\u6676\u4f53\u6676\u683c\u51e0\u4f55\u517c\u5bb9\u7684\u53ef\u7ed3\u5408\u7684\u6a21\u4f53\u3002\u7efc\u5408\u6765\u770b\uff0c\u8fd9\u4e9b\u53d1\u73b0\u8868\u660e\u4e00\u79cd\u65b0\u65b9\u6cd5\u7684\u53d1\u73b0\uff0c\u8fd9\u79cd\u65b9\u6cd5\u80fd\u591f\u5c06\u5bcc\u52d2\u70ef\u5206\u5b50\u7ec4\u88c5\u6210\u591a\u79cd\u591a\u6837\u7684\u6676\u683c\u7ed3\u6784\uff0c\u4ece\u800c\u5f97\u5230\u6240\u9700\u8981\u7684\u8bbe\u8ba1\u51fa\u7684\u65b0\u6027\u8d28\u3002<\/p>\n

\u5c0f\u7f16\u6ce8\uff1a
\n1\uff0c\u6a21\u4f53<\/strong>\uff1a\u5c5e\u4e8e\u86cb\u767d\u8d28\u7684\u4e8c\u7ea7\u7ed3\u6784\uff0c\u8868\u793a\u86cb\u767d\u8d28\u4e2d\u5177\u6709\u7279\u5b9a\u7a7a\u95f4\u6784\u8c61\u548c\u7279\u5b9a\u529f\u80fd\u7684\u7ed3\u6784\u6210\u5206\u3002
\n2\uff0cCOP<\/strong>\uff1aC60-organizing peptide, \u5373\u7ed3\u5408\u6709C60\u7684\u80bd\u3002\u4f5c\u8005\u901a\u8fc7\u8d85\u58f0\u5904\u7406\uff0c\u5c06C60\u6eb6\u89e3\u5728\u80bd\u7684\u6c34\u6eb6\u6db2\u4e2d\u5f97\u5230\uff0c\u6587\u4e2d\u5c06\u5176\u7b80\u79f0\u4e3aCOP\uff1b\u00a0C60Sol<\/strong>\uff1a C60\u5421\u54af\u70f7\u916e\u4e09\u7fa7\u9178\uff0c\u5373\u5728C60\u5206\u5b50\u4e0a\u4fee\u9970\u4e0a\u5421\u54af\u70f7\u916e\u4e09\u7fa7\u9178\uff0c\u5f97\u5230\u4e86\u4e00\u79cd\u6c34\u6eb6\u6027\u66f4\u597d\u7684C60\u7c7b\u4f3c\u7269\uff0c\u76f8\u5f53\u4e8e\u63d0\u9ad8\u4e86\u6c34\u6eb6\u6027\u7684C60\u7b49\u4ef7\u7269\u3002\u4e3a\u65b9\u4fbf\u63cf\u8ff0\u672c\u6587\u6cbf\u7528\u4f5c\u8005\u539f\u6587\u4e2d\u7684\u8fd9\u4e24\u4e2a\u7b80\u79f0\u3002<\/p>\n

\u6587\u732e\u56fe\u89e3<\/strong><\/p>\n

\"ncomms11429-f1\"<\/p>\n

\u56fe1 \u86cb\u767d\u8d28-C60\u7684\u8d85\u7ec4\u88c5<\/strong><\/p>\n

a\uff0c \u7a33\u5b9a\u4e14\u7edd\u7f18\u7684COP\u56db\u805a\u4f53\u901a\u8fc7\u8868\u9762\u7ed3\u5408\u4f4d\u70b9\uff08\u5305\u542b\u916a\u6c28\u9178\u6b8b\u57fa\u548c\u5176\u4ed6\u82b3\u9999\u65cf\u4fa7\u94fe\u7b49\uff09\u4e0eC60\u57fa\u56e2\u76f8\u4e92\u4f5c\u7528\uff0c\u5e76\u8fdb\u4e00\u6b65\u4e0e\u5bcc\u52d2\u70ef\u81ea\u7ec4\u88c5\u6210\u4e3a\u5171\u6676\u9635\u5217.
\nb\uff0c C60\/COP \u60ac\u6d6e\u6db2\u548c\u7eafCOP\u7684\u7d2b\u5916\u5438\u6536\u5149\u8c31\u663e\u793a\uff0c\u539f\u59cb\u7684\u5bcc\u52d2\u70ef\uff08\u7eff\u8272\u7ebf\uff09\u6eb6\u89e3\u5728\u4e86\u542b\u6709\u86cb\u767d\u8d28\u7684\u6c34\u76f8\u4e2d.
\nc\uff0c \u7eafCOP\u53ca\u5176\u4e0eC60\u6216C60Sol\u7ed3\u5408\u540e\u7684\u4f53\u79ef\u6392\u9664\u8272\u8c31\u56fe\uff08SEC\uff09\u66f2\u7ebf. \u4e0a\u4e0b\u4e24\u56fe\u663e\u793a\u5206\u522b\u5728340nm\u548c220nm\u5904\u7684\u5438\u5149\u5ea6. \u8f83\u4f4e\u7684\u5cf0\u5347\u9ad8\uff0c\u662f\u7531\u4e8eC60\u6216C60Sol\u7684\u52a0\u5165\u4ea7\u7269\u4e0eCOP\u516b\u805a\u4f53\u7684\u5206\u5b50\u91cf\u4e00\u81f4.
\nd\uff0c \u6bcf\u4e2aC60Sol-COP\u6676\u4f53\u4e2d\u7684COP\u56db\u805a\u4f53\u4e0e\u56db\u4e2a\u5bcc\u52d2\u70ef\u76f8\u8fde\uff08\u6bcf\u6761\u94fe\u4e00\u4e2a\uff09\uff0c\u6bcf\u4e2a\u5bcc\u52d2\u70ef\u6954\u5165\u4e24\u4e2a\u76f8\u90bb\u7684COP\u56db\u805a\u4f53\u4e4b\u95f4\uff0c\u6574\u4f53\u4e0a\u4e3a\u4e24\u4e2a\u5bcc\u52d2\u70ef\u5bf9\u5e94\u4e00\u4e2aCOP\u56db\u805a\u4f53.
\ne\uff0c C60Sol-COP\u6676\u4f53\u7acb\u4f53\u7535\u5b50\u5bc6\u5ea6\u56fe. \u663e\u793a\u4e86C60(\u6a59\u8272\u77ed\u68d2)\u7684\u7535\u5b50\u5bc6\u5ea6\uff0cC60\u5206\u5b50\u5939\u5728\u76f8\u90bb\u7684COPs\u7684\u03c0-\u03c0\u5806\u79ef\u7684\u916a\u6c28\u9178\u6b8b\u57fa\u4e4b\u95f4.
\nf\uff0c C60\u914d\u4f4d\u7684\u6b8b\u57fa\u7528\u77ed\u68d2\u548c\u6807\u7b7e\u6807\u793a.
\ng\uff0c \u4e0eC60\u914d\u4f4d\u4f4d\u70b9\u7684\u8868\u9762\u63cf\u8ff0\uff0c\u7528\u771f\u7a7a\u4e2d\u76f8\u5bf9\u7535\u52bf\u8868\u793a\uff08\u7ea2\u8272\u5230\u84dd\u8272\u8868\u793a\u6b63\u7535\u52bf\u5230\u8d1f\u7535\u52bf\uff09<\/p>\n

\"ncomms11429-f2\"<\/p>\n

\u56fe2 COP\u6676\u4f53\u7684\u53d8\u5316\u53ca\u4e0e\u5bcc\u52d2\u70ef\u7684\u7ed3\u5408. <\/strong><\/p>\n

a\uff0c COP\uff08\u7eff\u8272\uff09\u548cC60Sol-COP\u7684\u91cd\u53e0\u87ba\u65cb\u675f\u6ca1\u6709\u660e\u663e\u7684\u7ed3\u6784\u6539\u53d8.\u5728\u65b9\u6846\u4e2d\u6807\u51fa\u7684\u662f\u5bcc\u52d2\u70ef\u7ed3\u5408\u4f4d\u70b9\u9644\u8fd1\u7684\u4fa7\u94fe\u7684\u5dee\u5f02.
\nb\uff0c \u5728C60Sol-COP\u4e2d\u7684\u82b3\u9999\u65cf\u916a\u6c28\u91789\uff08Tyr9\uff09\u6b8b\u57fa\u4e4b\u95f4\u7684\u8ddd\u79bb\u53d1\u751f\u53d8\u5316\u548c\u8c03\u6574\uff0c\u4ee5\u7ed3\u5408\u5bcc\u52d2\u70ef.
\nc\uff0c \u4e0d\u540c\u89d2\u5ea6\uff08\u89c6\u89d2\uff09\u4e0b\u7684COP-\u5bcc\u52d2\u70ef\u6676\u683c
\nd\uff0c COP\u4e0eC60Sol-COP\u6676\u4f53\u7684\u6676\u683c\u7ed3\u6784\u7684\u663e\u8457\u53d8\u5316.\u4ece\u4e0a\u65b9\u770b\uff0cC60Sol-COP\u5f62\u6210\u4e00\u79cd\u8702\u5de2\u7ed3\u6784\uff08ii\uff09,\u800cCOP\u5f62\u6210\u56db\u805a\u4f53\u7acb\u65b9\u56fe\u6848.<\/p>\n

\"ncomms11429-f3\"<\/p>\n

\u56fe3 \u5bcc\u52d2\u70ef\u7684\u7ec4\u88c5\u4f7f\u5f97\u6676\u4f53\u5177\u6709\u7535\u5b50\u8f93\u8fd0\u7684\u80fd\u529b<\/strong><\/p>\n

a\uff0c \u4e09\u4e2a\u89d2\u5ea6\u4e0b\u7684C60Sol-COP\u6676\u4f53\u6676\u683c\u793a\u610f\u56fe
\nb\uff0c C60\u57fa\u56e2\u5728\u7ec4\u88c5\u4e2d\u4ee5\u87ba\u65cb\u65b9\u5f0f\u6cbf\u7740\u96a7\u9053\u5185\u90e8\u6392\u5217
\nc\uff0c \u96a7\u9053\u7684\u4fa7\u89c6\u56fe\u663e\u793a\u4e86\u5185\u5176\u90e8\u7684\u76f8\u90bbC60\u95f4\u7684\u6700\u8fd1\u8ddd\u79bb
\nd\uff0c \u534a\u5bf9\u6570\u7684\u7535\u6d41-\u7535\u538b\u7279\u5f81\u66f2\u7ebf\uff08\u5373\u5b89-\u4f0f\u7279\u6027\u66f2\u7ebf\uff09. C60Sol-COP\u8d85\u6676\u4f53\uff08\u7ea2\u8272\u5706\u70b9\uff09\uff1b\u65e0\u5b9a\u578b\u7684C60Sol-COP\uff08\u6a59\u8272\u83f1\u5f62\uff09\uff1b\u7eafC60\u7532\u82ef\u6eb6\u6db2\u84b8\u5e72\u5f97\u5230\u65e0\u5b9a\u578b\u7684C60\u8584\u819c\uff08\u7eff\u8272\u65b9\u5f62\uff09\uff1b\u6676\u4f53\u7f13\u51b2\u6eb6\u6db2\uff08\u84dd\u8272\u4e09\u89d2\u5f62\uff09\uff1bCOP-\u86cb\u767d\u8d28\u6676\u4f53\uff08\u7d2b\u8272\u65b9\u73af\uff09.<\/p>\n

\u539f\u6587\u53c2\u8003\u94fe\u63a5\uff1aResearchers create artificial protein to control assembly of buckyballs<\/a><\/p>\n

\u6587\u732e\u539f\u6587\u94fe\u63a5\uff1aProtein-directed self-assembly of a fullerene crystal<\/a><\/p>\n

\u6587\u732e\u8865\u5145\u56fe\u8868\u94fe\u63a5\uff1aSupplementary Information<\/a><\/p>\n

\u611f\u8c22\u6750\u6599\u4eba\u7f16\u8f91\u90e8\u5c09\u8c37\u96e8\u63d0\u4f9b\u7d20\u6750\uff01\u672c\u6587\u7531\u674e\u5353\u6574\u7406\u7f16\u8bd1\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"

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