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\u3010\u5f15\u8a00\u3011<\/strong><\/p>\n

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\u3010\u6210\u679c\u7b80\u4ecb\u3011<\/strong><\/p>\n

\u8fd1\u65e5\uff0c\u6d1b\u6851\u8054\u90a6\u7406\u5de5\u5b66\u9662Francesco Stellacci\uff08\u901a\u8baf\u4f5c\u8005\uff09<\/strong>\u56e2\u961f\u8bbe\u8ba1\u4e86\u6a21\u4effHSPG\u7684\u6297\u75c5\u6bd2\u7eb3\u7c73\u9897\u7c92\uff0c\u75c5\u6bd2\u4e0eVAL\u91cd\u590d\u5355\u5143\u7684\u7ed3\u5408\u6700\u7ec8\u4ea7\u751f\u4f7f\u75c5\u6bd2\u4e0d\u53ef\u9006\u53d8\u5f62\u7684\u529b\uff08\u301c190pN\uff09\u3002\u75c5\u6bd2\u68c0\u6d4b\uff0c\u7535\u5b50\u663e\u5fae\u955c\u56fe\u50cf\u548c\u5206\u5b50\u52a8\u529b\u5b66\u6a21\u62df\u90fd\u8bc1\u660e\u4e86\u6240\u63d0\u51fa\u7684\u673a\u5236\u3002\u8fd9\u4e9b\u9897\u7c92\u4e0d\u5177\u6709\u7ec6\u80de\u6bd2\u6027\uff0c\u5e76\u4e14\u4f53\u5916\u7eb3\u6469\u5c14\u4e0d\u53ef\u9006\u6d3b\u6027\u53ef\u4ee5\u5bf9\u6297\u5355\u7eaf\u75b1\u75b9\u75c5\u6bd2\uff08HSV\uff09\uff0c\u4eba\u4e73\u5934\u7624\u75c5\u6bd2\uff0c\u547c\u5438\u9053\u5408\u80de\u75c5\u6bd2\uff08RSV\uff09\uff0c\u767b\u9769\u70ed\u548c\u6162\u75c5\u6bd2\u3002\u76f8\u5173\u6210\u679c\u4ee5\u9898\u4e3a\u201cBroad-spectrum non-toxic antiviral nanoparticles with a virucidal inhibition mechanism<\/strong>\u201d\u53d1\u8868\u5728\u4e86Nature Materials<\/strong>\u4e0a\u3002<\/p>\n

\u3010\u56fe\u6587\u5bfc\u8bfb\u3011<\/strong><\/p>\n

\u56fe1 MUS\uff1aOT-NPs\u7684\u6297\u75c5\u6bd2\u6d3b\u6027<\/strong><\/p>\n

\"\"<\/p>\n

a\uff09MUS\uff1aOT-NPs\u4e0eMES-NPs\u76f8\u6bd4\u7684\u6297\u75c5\u6bd2\u6d3b\u6027<\/p>\n

b\uff09\u809d\u7d20\uff0cMES-NP\u548cMUS\uff1aOT-NPs\u75c5\u6bd2\u611f\u67d3\u6027\u66f2\u7ebf\u548c\u6297\u75c5\u6bd2\u6d4b\u5b9a<\/p>\n

c\uff09\u9488\u5bf9HPV-16\uff0cRSV\uff0cLV-VSV-G\uff08\u663e\u793a\u4e3aLV\uff09\u548cDENV-2\u75c5\u6bd2\u7684MUS\u5305\u8986\u7684NPs\u7684\u6297\u75c5\u6bd2\u6d3b\u6027<\/p>\n

d\uff09MUS\uff1aOT-NPs\u5bf9HSV-2\u7684\u75c5\u6bd2\u611f\u67d3\u6027\u5bf9\u65f6\u95f4\uff08\u5206\u949f\uff09\u7684\u6291\u5236<\/p>\n

\u56fe2 HSV-2\u53ca\u5176\u4e0eMUS\uff1aOT-NPs\u7684\u5173\u8054<\/strong><\/p>\n

\"\"<\/p>\n

a-c\uff09\u4f7f\u7528\u5e72\u71e5\u9634\u6027\u67d3\u8272\u7684TEM\uff08a\uff09\u6216\u672a\u67d3\u8272\u7684\u4f4e\u6e29-TEM\uff08b\uff0cc\uff09<\/p>\n

d\uff09\u4e0eHSV-2\u6709\u5173\u7684NPs\uff08MES\u6216MUS\uff1aOT\uff09\u7684\u767e\u5206\u6bd4\u548c\u5206\u5e03<\/p>\n

\u56fe3 \u5206\u5b50\u52a8\u529b\u5b66\u6a21\u62df<\/strong><\/p>\n

\"\"<\/p>\n

a\uff09\u78fa\u5316MUS\u7684\u9876\u89c6\u56fe\uff1aOT-NP\uff082.4nm\u6838\u5fc3\uff09<\/p>\n

b\uff09\u793a\u610f\u56fe\u8bf4\u660e\u4e86MUS\u578bNPs\u4e0eHSPG\u7ed3\u5408\u6b8b\u57fa\u7684\u5f3a\u591a\u4f4d\u70b9\u7ed3\u5408\u80fd\u591f\u5f15\u8d77\u4e0d\u53ef\u9006\u7684\u6539\u53d8<\/p>\n

\u3010\u5c0f\u7ed3\u3011<\/strong><\/p>\n

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\u6587\u732e\u94fe\u63a5\uff1a<\/strong>Broad-spectrum non-toxic antiviral nanoparticles with a virucidal inhibition mechanism<\/a>\uff08Nat. Mater., 2017, DOI:10.1038\/nmat5053\uff09<\/p>\n

\u6587\u7531\u6750\u6599\u4eba\u751f\u7269\u6750\u6599\u7ec4Allen\u4f9b\u7a3f\uff0c\u6750\u6599\u725b\u6574\u7406\u7f16\u8f91\u3002<\/p>\n

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\n <\/b><\/strong><\/p>\n

\u6750\u6599\u6d4b\u8bd5\uff0c\u6570\u636e\u5206\u6790\uff0c\u4e0a<\/strong>\u6d4b\u8bd5\u8c37<\/strong><\/a>\uff01<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"

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