{"id":116275,"date":"2017-12-11T14:00:30","date_gmt":"2017-12-11T06:00:30","guid":{"rendered":"\/\/m.iemloyee.com\/?p=116275"},"modified":"2017-12-09T16:31:10","modified_gmt":"2017-12-09T08:31:10","slug":"itamar-willner%e6%95%99%e6%8e%88adv-funct-mater-%ef%bc%9a%e5%9f%ba%e4%ba%8e%e6%a0%b8%e9%85%b8%e7%9a%84%e6%b0%b4%e5%87%9d%e8%83%b6%e6%b6%82%e8%a6%86%e7%9a%84mof%e7%ba%b3%e7%b1%b3%e7%b2%92%e5%ad%90","status":"publish","type":"post","link":"\/\/m.iemloyee.com\/?p=116275","title":{"rendered":"Itamar Willner\u6559\u6388Adv. Funct. Mater.\uff1a\u57fa\u4e8e\u6838\u9178\u7684\u6c34\u51dd\u80f6\u6d82\u8986\u7684MOF\u7eb3\u7c73\u7c92\u5b50\u7528\u4f5c\u523a\u6fc0\u54cd\u5e94\u7684\u53ef\u63a7\u836f\u7269\u91ca\u653e"},"content":{"rendered":"

\u3010\u5f15\u8a00\u3011<\/strong><\/p>\n

\u91d1\u5c5e\u6709\u673a\u6846\u67b6 (MOF)\uff0c\u51ed\u501f\u5176\u9ad8\u5b54\u9699\u7279\u5f81\u53ef\u7528\u4e8e\u591a\u79cd\u591a\u6837\u7684\u5e94\u7528\uff0c\u5982\u6c14\u4f53\u5438\u9644\u548c\u5206\u79bb\u3001\u4f5c\u4e3a\u50ac\u5316\u57fa\u4f53\u3001\u4f5c\u4e3a\u836f\u7269\u8f7d\u4f53\u7528\u4e8e\u53ef\u63a7\u836f\u7269\u91ca\u653e\u3001\u4f20\u611f\u5668\u7b49\uff0c\u5438\u5f15\u4e86\u7814\u7a76\u8005\u4eec\u6781\u5927\u7684\u5174\u8da3\u3002\u6b64\u5916\uff0cDNA\u7eb3\u7c73\u6280\u672f\u5f15\u5165\u4e86\u201cDNA\u5f00\u5173\u201d\u7684\u6982\u5ff5\uff0c\u5e76\u53d6\u5f97\u4e86\u76f8\u5e94\u8fdb\u5c55\u3002\u5176\u4e2d\u8d85\u5206\u5b50\u6838\u9178\u7ed3\u6784\uff0c\u5728\u5b58\u5728\u5408\u9002\u4fe1\u53f7\u548c\u9006\u4fe1\u53f7\u65f6\u53ef\u4ee5\u53d1\u751f\u53ef\u9006\u8f6c\u6362\uff0c\u56e0\u6b64\u53ef\u7528\u4e8e\u8bbe\u8ba1DNA\u673a\u5668\u91cd\u65b0\u8f6c\u6362DNA\u7eb3\u7c73\u7ed3\u6784\uff0c\u7528\u4e8e\u5408\u6210\u57fa\u4e8eDNA\u7684\u6c34\u51dd\u80f6\u53d1\u751f\u80f6\u72b6\u548c\u6db2\u4f53\u72b6\u6001\u7684\u53ef\u9006\u8f6c\u53d8\uff0c\u4e5f\u53ef\u7528\u4e8e\u5efa\u6784\u624b\u6027\u7b49\u79bb\u5b50\u6fc0\u5143\u7684\u7eb3\u7c73\u7c92\u5b50\u7684\u7ec4\u88c5\u3002\u56e0\u6b64\uff0c\u591a\u5b54\u7684MOF\u7eb3\u7c73\u7c92\u5b50\u8d1f\u8f7d\u836f\u7269\uff0c\u5e76\u8fde\u63a5\u53ef\u523a\u6fc0\u54cd\u5e94\u7684\u6838\u9178\u5c01\u7aef\u5355\u5143\uff0c\u63d0\u4f9b\u4e86\u4e00\u79cd\u901a\u7528\u65b9\u5f0f\u7528\u4e8e\u5f00\u53d1\u667a\u80fd\u836f\u7269\u8f7d\u4f53\u3002\u7136\u800c\uff0c\u6709\u5173\u6838\u9178\u529f\u80fd\u5316\u7684MOF\u7eb3\u7c73\u7c92\u5b50\u7684\u62a5\u9053\u975e\u5e38\u5c11\uff0c\u800c\u4e14MOF\u7eb3\u7c73\u7c92\u5b50\u5c01\u7aef\u8fc7\u7a0b\u4e2d\u5bfc\u81f4\u4e86\u5176\u8d1f\u8f7d\u91cf\u7684\u964d\u4f4e\u3002\u56e0\u6b64\uff0c\u63a2\u7d22\u51fa\u4e00\u4e9b\u65b0\u9896\u7684MOF\u7eb3\u7c73\u7c92\u5b50\u4e0e\u6838\u9178\u7684\u5c01\u7aef\u65b9\u6cd5\u4ece\u800c\u6709\u6548\u907f\u514d\u5176\u5c40\u9650\u6027\u81f3\u5173\u91cd\u8981\u3002<\/p>\n

\u3010\u6210\u679c\u7b80\u4ecb\u3011<\/strong><\/p>\n

\u8fd1\u65e5\uff0c\u4ee5\u8272\u5217\u8036\u8def\u6492\u51b7\u5e0c\u4f2f\u6765\u5927\u5b66\u7684<\/strong>Itamar Willner<\/strong>\u9662\u58eb<\/strong>(<\/strong>\u901a\u8baf\u4f5c\u8005<\/strong>)<\/strong>\u7b49\u4eba\u5728Advanced Functional Materials<\/strong>\u671f\u520a\u4e0a\u53d1\u8868\u4e86\u9898\u4e3a\u201cStimuli-Responsive Nucleic Acid-Based Polyacrylamide Hydrogel-Coated Metal\u2013Organic Framework Nanoparticles for Controlled Drug Release<\/strong>\u201d\u7684\u6587\u7ae0\uff0c\u6587\u4e2d\u4f5c\u8005\u5229\u7528MOF\u7eb3\u7c73\u7c92\u5b50\u8d1f\u8f7dDOX\u6297\u764c\u836f\u7269\uff0c\u5e76\u4e14\u6d82\u8986\u4e86\u4e00\u79cd\u53ef\u523a\u6fc0\u54cd\u5e94\u7684\u805a\u4e19\u70ef\u9170\u80fa\/DNA\u6c34\u51dd\u80f6\u3002\u8fd9\u79cd\u6c34\u51dd\u80f6\u7684\u4ea4\u8054\u662f\u901a\u8fc7\u542b\u6709\u6297ATP\u6838\u9178\u9002\u4f53\u7684\u6838\u9178\u53cc\u94fe\u4f53\u5728\u7b3c\u5f62\u6784\u9020\u4e2d\u5b9e\u73b0\u7684\u3002\u5f53\u5b58\u5728ATP\u65f6\uff0c\u8fd9\u79cd\u4ea4\u8054\u7684\u6865\u63a5\u5355\u5143\u56e0\u4e3a\u5f62\u6210ATP-\u6838\u9178\u9002\u4f53\u590d\u5408\u7269\u800c\u88ab\u5206\u79bb\uff0c\u8fdb\u800c\u5bfc\u81f4\u6c34\u51dd\u80f6\u58f3\u7684\u5206\u79bb\uff0c\u4ece\u800c\u91ca\u653e\u836f\u7269\u3002<\/p>\n

\u3010\u56fe\u6587\u7b80\u4ecb\u3011<\/strong><\/p>\n

\u56fe\u4e00\uff1a\u6c34\u51dd\u80f6\u6d82\u8986\u7684<\/strong>MOF<\/strong>\u7eb3\u7c73\u7c92\u5b50<\/strong>\u5408\u6210\u8fc7\u7a0b\u793a\u610f\u56fe<\/strong>\u53ca\u5fae\u89c2\u5f62\u8c8c\u8868\u5f81<\/strong><\/p>\n

\"\"<\/p>\n

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\uff08B\uff09\u6c34\u51dd\u80f6\u6d82\u8986\u7684MOF\u7eb3\u7c73\u7c92\u5b50\u901a\u8fc7\u5f62\u6210ATP-\u6838\u9178\u9002\u4f53\u590d\u5408\u7269\u91ca\u653e\u836f\u7269\u7684\u793a\u610f\u56fe\u3002ATP\u63a5\u89e6\u8be5\u590d\u5408\u7cfb\u7edf\u540e\uff0c\u4f1a\u5f62\u6210ATP-\u6838\u9178\u9002\u4f53\u590d\u5408\u7269\uff0c\u4ece\u800c\u9020\u6210\u6865\u63a5\u5355\u5143\u7684\u5206\u79bb\uff0c\u8fdb\u800c\u65ad\u88c2\u90e8\u5206\u6c34\u51dd\u80f6\uff0c\u5f15\u8d77\u836f\u7269\u91ca\u653e\u3002<\/p>\n

\uff08C\uff09MOF\u7eb3\u7c73\u7c92\u5b50SEM\u56fe\u50cf\u3002MOF\u7eb3\u7c73\u7c92\u5b50\u5448\u73b0\u51fa\u4e00\u79cd\u53cc\u91d1\u5b57\u5854\u7ed3\u6784\uff0c\u5e76\u4e14\u5c3a\u5bf8\u5728280-350 nm\u3002<\/p>\n

\uff08D\uff09\u6c34\u51dd\u80f6\u6d82\u8986\u7684MOF\u7eb3\u7c73\u7c92\u5b50SEM\u56fe\u50cf\u3002MOF\u7eb3\u7c73\u7c92\u5b50\u6bd4\u8f83\u5c16\u9510\u7684\u89d2\u6d88\u5931\u4e86\uff0c\u800c\u4e14\u7c92\u5b50\u7684\u8868\u9762\u8d8a\u6765\u8d8a\u5149\u6ed1\u3002<\/p>\n

\u56fe\u4e8c\uff1a\u6c34\u51dd\u80f6\u6d82\u8986\u7684<\/strong>MOF<\/strong>\u7eb3\u7c73\u7c92\u5b50<\/strong>\u5728<\/strong>ATP<\/strong>\u4f5c\u7528\u4e0b\u7684<\/strong>DOX<\/strong>\u91ca\u653e\u7279\u5f81<\/strong><\/p>\n

\"\"<\/p>\n

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\uff08B\uff09\u4e0d\u540cATP\u6d53\u5ea6\u4e0b\u7684DOX\u4ece\u6c34\u51dd\u80f6\u6d82\u8986\u7684MOF\u7eb3\u7c73\u7c92\u5b50\u4e2d\u91ca\u653e\u7684\u8367\u5149\u5149\u8c31\uff1aa) 0\u00d710-3<\/sup> M\uff1bb) 5\u00d710-3<\/sup> M\uff1bc) 10\u00d710-3<\/sup> M\uff1bd) 25\u00d710-3<\/sup> M\uff1be) 50\u00d710-3<\/sup> M\u3002\u4ece\u4e2d\u53ef\u4ee5\u770b\u51faDOX\u7684\u91ca\u653e\u53ef\u4ee5\u901a\u8fc7\u8c03\u8282ATP\u7684\u6d53\u5ea6\u63a7\u5236\uff0c\u4e14\u968f\u7740ATP\u6d53\u5ea6\u589e\u52a0\uff0c\u91ca\u653e\u91cf\u9010\u6e10\u589e\u52a0\u3002<\/p>\n

\uff08C\uff09\u6dfb\u52a0\u4e86a) ATP\uff0c0\u00d710-3<\/sup> M\uff1bb) TTP\uff0c50\u00d710-3<\/sup> M\uff1bc) GTP\uff0c50\u00d710-3<\/sup> M\uff1bd) CTP\uff0c50\u00d710-3<\/sup> M\u548c e) ATP\uff0c50\u00d710-3<\/sup> M\u540e\uff0cDOX\u4ece\u6c34\u51dd\u80f6\u6d82\u8986\u7684MOF\u7eb3\u7c73\u7c92\u5b50\u4e2d\u7684\u9009\u62e9\u6027\u91ca\u653e\uff0c\u9664ATP\u5916\u5176\u4ed6\u6838\u82f7\u4e09\u78f7\u9178\u4e0d\u80fd\u523a\u6fc0\u8d1f\u8f7d\u7269\u7684\u91ca\u653e\u3002<\/p>\n

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\u56fe\u4e09\uff1a<\/strong>\u6c34\u51dd\u80f6\u6d82\u8986\u7684<\/strong>MOF<\/strong>\u7eb3\u7c73\u7c92\u5b50\u5728\u5d4c\u5165\u4e0d\u540c\u7ec6\u80de\u4e0b\u7684\u5171\u805a\u7126\u663e\u5fae\u955c\u56fe\u50cf<\/strong><\/p>\n

\"\"<\/p>\n

\uff08A\uff09\u8d1f\u8f7dDOX\u7684\u6838\u9178\u5c01\u7aef\u7684MOF\u7eb3\u7c73\u7c92\u5b50\u8fdb\u5165I) MCF-10A \u4e73\u817a\u4e0a\u76ae\u7ec6\u80de\u548c II) MDA-MB-231\u4e73\u817a\u764c\u7ec6\u80de\u7684\u5171\u805a\u7126\u663e\u5fae\u56fe\u50cf\uff1b\u8d1f\u8f7dDOX\u7684\u6c34\u51dd\u80f6\u6d82\u8986\u7684MOF\u7eb3\u7c73\u7c92\u5b50\u8fdb\u5165III) MCF-10A \u4e73\u817a\u4e0a\u76ae\u7ec6\u80de\u548c IV) MDA-MB-231\u4e73\u817a\u764c\u7ec6\u80de\u7684\u5171\u805a\u7126\u663e\u5fae\u56fe\u50cf\u3002\u7ea2\u8272\u8367\u5149\u70b9\u8868\u793a\u4e86\u6e17\u900f\u8fdb\u5165\u7ec6\u80de\u7684MOF\u7eb3\u7c73\u7c92\u5b50\uff0c\u4ece\u4e2d\u53ef\u4ee5\u770b\u51fa\u53ea\u6709\u5c11\u91cf\u7684MOF\u7eb3\u7c73\u7c92\u5b50\u6e17\u900f\u8fdb\u5165MCF-10A\u4e73\u817a\u4e0a\u76ae\u7ec6\u80de\uff0c\u800c\u7531\u4e8e\u764c\u7ec6\u80de\u589e\u5f3a\u7684\u6e17\u900f\u548c\u4fdd\u7559\u6548\u5e94\uff0c\u66f4\u591a\u7684MOF\u7eb3\u7c73\u7c92\u5b50\u6e17\u900f\u8fdb\u5165\u4e86\u4e73\u817a\u764c\u7ec6\u80de\u3002<\/p>\n

\uff08B\uff09I) A\u4e2d(II)\u7684\u653e\u5927\u56fe\u50cf\uff0c II) A\u4e2d(IV)\u7684\u653e\u5927\u56fe\u50cf\u3002II\u4e2d\u6a21\u7cca\u7684\u533a\u57df\uff08\u9ec4\u5708\uff09\u662f\u56e0\u4e3a\u5728MOF\u7eb3\u7c73\u7c92\u5b50\u4e0a\u6d82\u8986\u7684\u6c34\u51dd\u80f6\u3002<\/p>\n

\u56fe\u56db\uff1a\u6c34\u51dd\u80f6\u6d82\u8986\u7684<\/strong>MOF<\/strong>\u7eb3\u7c73\u7c92\u5b50\u5bf9\u4e0d\u540c\u764c\u7ec6\u80de\u7684\u6bd2\u6027\u7814\u7a76<\/strong><\/p>\n

\"\"<\/p>\n

MOF\u7eb3\u7c73\u7c92\u5b50\u5bf9\u4e73\u817a\u764c\u7ec6\u80de\u548c\u6b63\u5e38\u4e73\u817a\u4e0a\u76ae\u7ec6\u80de\u7684\u6bd2\u6027\uff1a<\/p>\n

a) \u5bf9\u7167\u7ec4\uff1b<\/p>\n

b) \u7ec6\u80de\u88ab\u6838\u9178\u5c01\u7aef\u7684MOF\u7eb3\u7c73\u7c92\u5b50\u5904\u7406\uff1b<\/p>\n

c) \u7ec6\u80de\u88ab\u6c34\u51dd\u80f6\u6d82\u8986\u7684MOF\u7eb3\u7c73\u7c92\u5b50\u5904\u7406\uff1b<\/p>\n

d) \u7ec6\u80de\u88ab\u8d1f\u8f7dDOX\u7684\u6838\u9178\u5c01\u7aef\u7684MOF\u7eb3\u7c73\u7c92\u5b50\u5904\u7406\uff1b<\/p>\n

e) \u7ec6\u80de\u88ab\u8d1f\u8f7dDOX\u7684\u6c34\u51dd\u80f6\u6d82\u8986\u7684MOF\u7eb3\u7c73\u7c92\u5b50\u5904\u7406\u3002\u4ece\u4e2d\u53ef\u4ee5\u770b\u51fa\u6c34\u51dd\u80f6\u6d82\u8986\u7684MOF\u7eb3\u7c73\u7c92\u5b50\u5904\u7406\u540e\u7684MDA-MB-231\u4e73\u817a\u764c\u7ec6\u80de\u7684\u5b58\u6d3b\u7387\u6700\u4f4e\u3002<\/p>\n

\u56fe\u4e94\uff1a\u6c34\u51dd\u80f6\u6d82\u8986\u7684<\/strong>MOF<\/strong>\u7eb3\u7c73\u7c92\u5b50\u5bf9\u4e73\u817a\u764c\u7ec6\u80de\u7684\u6bd2\u6027\u7814\u7a76<\/strong>
\n <\/strong><\/p>\n

\"\"<\/strong><\/p>\n

\uff08A\uff09<\/strong>\u572824 h\u548c120 h\u540e\u51dd\u805a\u7ec6\u80de\u7684\u76f8\u5dee\u548c\u7ea2\u8272\u8367\u5149\u56fe\u50cf\uff08\u7ea2\u8272\u8367\u5149\u4ee3\u8868\u4e86\u7ec6\u80de\u7684\u51cb\u4ea1\uff09\uff1b<\/p>\n

\uff08B\uff09<\/strong>\u65f6\u95f4\u76f8\u5173\u7684\u4e73\u817a\u764c\u7ec6\u80de\u51cb\u4ea1\u66f2\u7ebf\u3002<\/p>\n

a) \u7ec6\u80de\u7528\u6ca1\u6709\u8d1f\u8f7d\u7684\u6c34\u51dd\u80f6\u6d82\u8986\u7684MOF\u7eb3\u7c73\u7c92\u5b50\u5904\u7406\u540e\uff0c<\/p>\n

b) \u7ec6\u80de\u7528\u8d1f\u8f7dDOX\u7684ATP\u54cd\u5e94\u7684\u6838\u9178\u5c01\u7aef\u7684MOF\u7eb3\u7c73\u7c92\u5b50\u5904\u7406\u540e\uff0c<\/p>\n

c) \u7ec6\u80de\u7528\u8d1f\u8f7dDOX\u7684ATP\u54cd\u5e94\u7684\u6c34\u51dd\u80f6\u6d82\u8986\u7684MOF\u7eb3\u7c73\u7c92\u5b50\u5904\u7406\u540e\u3002<\/p>\n

\u3010\u5c0f\u7ed3\u3011<\/strong><\/p>\n

\u672c\u6587\u4ecb\u7ecd\u4e86\u53ef\u523a\u6fc0\u54cd\u5e94\u7684\u57fa\u4e8e\u6838\u9178\u7684\u6c34\u51dd\u80f6\u6d82\u8986\u7684MOF\u7eb3\u7c73\u7c92\u5b50\u4f5c\u4e3a\u4e00\u79cd\u65b0\u9896\u7684\u590d\u5408\u836f\u7269\u8f7d\u4f53\u3002ATP\u54cd\u5e94\u7684\u805a\u4e19\u70ef\u9170\u80fa\u6c34\u51dd\u80f6MOF\u7eb3\u7c73\u7c92\u5b50\u76f8\u6bd4\u4e8e\u7528\u53cc\u94fe\u6838\u9178\u5355\u5143\u5c01\u7aef\u7684MOF\u7eb3\u7c73\u7c92\u5b50\u4f5c\u4e3a\u836f\u7269\u8f7d\u4f53\u7684\u6548\u7387\u5f97\u5230\u4e86\u5f88\u5927\u7684\u63d0\u5347\u3002\u6c34\u51dd\u80f6\u6d82\u8986\u7684MOF\u7eb3\u7c73\u7c92\u5b50\u7684\u8d1f\u8f7d\u91cf\u5f97\u5230\u4e86\u53ef\u89c2\u5730\u589e\u52a0\uff0c\u5e76\u4e14\u4ece\u8be5\u7cfb\u7edf\u4e2d\u8d1f\u8f7d\u836f\u7269\u7684\u6cc4\u6f0f\u91cf\u4e5f\u5f97\u5230\u4e86\u964d\u4f4e\u3002\u6b64\u5916\uff0c\u8be5\u590d\u5408\u836f\u7269\u8f7d\u4f53\u5bf9MD-MBA-231\u764c\u7ec6\u80de\u7684\u7ec6\u80de\u6bd2\u6027\u4e5f\u975e\u5e38\u9ad8\u3002\u56e0\u6b64\uff0c\u8fd9\u4e9b\u7ed3\u679c\u8868\u660e\u4f5c\u8005\u6210\u529f\u5f00\u53d1\u4e86\u4e00\u79cd\u6027\u80fd\u63d0\u5347\u7684\u53ef\u523a\u6fc0\u54cd\u5e94\u7684\u6c34\u51dd\u80f6-MOF\u7eb3\u7c73\u7c92\u5b50\u4f5c\u4e3a\u836f\u7269\u8f7d\u4f53\u3002<\/p>\n

\u6587\u732e\u94fe\u63a5\uff1a<\/strong><\/p>\n

Stimuli-Responsive Nucleic Acid-Based Polyacrylamide Hydrogel-Coated Metal\u2013Organic Framework Nanoparticles for Controlled Drug Release <\/a>(Adv. Funct. Mater. 2017, DOI: 10.1002\/adfm.201705137<\/a>)<\/p>\n

\u672c\u6587\u7531\u6750\u6599\u4eba\u7f16\u8f91\u90e8\u661d\u840d\u7f16\u8bd1\uff0c\u70b9\u6211\u52a0\u5165\u6750\u6599\u4eba\u7f16\u8f91\u90e8<\/a>\u3002<\/p>\n

\u6750\u6599\u6d4b\u8bd5\uff0c\u6570\u636e\u5206\u6790\uff0c\u4e0a\u6d4b\u8bd5\u8c37<\/a>\uff01<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"

\u3010\u5f15\u8a00\u3011 \u91d1\u5c5e\u6709\u673a\u6846\u67b6 (MOF)\uff0c\u51ed\u501f\u5176\u9ad8\u5b54\u9699\u7279\u5f81\u53ef\u7528\u4e8e\u591a\u79cd\u591a\u6837\u7684\u5e94\u7528\uff0c\u5982\u6c14\u4f53\u5438\u9644\u548c\u5206\u79bb\u3001\u4f5c\u4e3a\u50ac\u5316\u57fa\u4f53\u3001\u4f5c\u4e3a\u836f\u7269\u8f7d\u4f53\u7528\u4e8e\u53ef\u63a7\u836f\u7269\u91ca\u653e\u3001\u4f20\u611f\u5668\u7b49\uff0c\u5438\u5f15\u4e86\u7814\u7a76\u8005\u4eec…<\/p>\n","protected":false},"author":3094,"featured_media":116278,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[215],"tags":[75,33,245],"class_list":["post-116275","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-jiedu","tag-biomaterial","tag-nano","tag-mof"],"_links":{"self":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts\/116275"}],"collection":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/users\/3094"}],"replies":[{"embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=116275"}],"version-history":[{"count":6,"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts\/116275\/revisions"}],"predecessor-version":[{"id":116378,"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/posts\/116275\/revisions\/116378"}],"wp:featuredmedia":[{"embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=\/wp\/v2\/media\/116278"}],"wp:attachment":[{"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=116275"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=116275"},{"taxonomy":"post_tag","embeddable":true,"href":"\/\/m.iemloyee.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=116275"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}